LOCUS       NZ_CRAW01000002        21709 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptococcus pneumoniae strain SMRU702, whole genome shotgun
            sequence.
ACCESSION   NZ_CRAW01000002
VERSION     NZ_CRAW01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  AUTHORS   Informatics,Pathogen.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAR-2015) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001193635.1-RS_2024_12_12
            Annotation Date                   :: 12/12/2024 01:34:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,158
            Genes (coding)                    :: 1,981
            CDSs (with protein)               :: 1,981
            Genes (RNA)                       :: 44
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 177
            CDSs (without protein)            :: 177
            Pseudo Genes (ambiguous residues) :: 0 of 177
            Pseudo Genes (frameshifted)       :: 66 of 177
            Pseudo Genes (incomplete)         :: 114 of 177
            Pseudo Genes (internal stop)      :: 46 of 177
            Pseudo Genes (multiple problems)  :: 43 of 177
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:02:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 21709
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CRAW01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21709
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..21709
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21709
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[536:1709](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      537..1709
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            <1..90
                     /locus_tag="AK725_RS12115"
                     /pseudo=""
     CDS             <1..90
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="AK725_RS12115"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="FSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            158..406
                     /locus_tag="AK725_RS01005"
                     /pseudo=""
     CDS             158..406
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /locus_tag="AK725_RS01005"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVSSSGSEFQSGW"
     gene            537..1709
                     /locus_tag="AK725_RS01010"
                     /old_locus_tag="ERS020212_00201"
     CDS             537..1709
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /locus_tag="AK725_RS01010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00201"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_000151960.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 4.8e-09,
                     bitscore: 29.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSIA
                     PLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFARS
                     FEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAMLIT
                     QNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQKRYQL
                     TLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGNIYTGS
                     LFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLNKLNQRT
                     ALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1709..2983
                     /locus_tag="AK725_RS01015"
                     /old_locus_tag="ERS020212_00202"
     CDS             1709..2983
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /locus_tag="AK725_RS01015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00202"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_050265477.1"
                     /transl_table=11
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTVA
                     DQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFTAQ
                     VHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVEQIK
                     GEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSLVTAS
                     CRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIATGNDWR
                     AIEAGAHAFASRDGHYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPRVALSHD
                     LLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGASESEVAP
                     LVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3018..3983)
                     /locus_tag="AK725_RS01020"
                     /old_locus_tag="ERS020212_00203"
     CDS             complement(3018..3983)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /locus_tag="AK725_RS01020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00203"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_000226001.1"
                     /transl_table=11
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMRELG
                     YKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDSEK
                     EREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAGGVL
                     AAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKEMEIK
                     NILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQLATIK
                     QPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(3964..5418)
                     /locus_tag="AK725_RS01025"
                     /old_locus_tag="ERS020212_00204"
     CDS             complement(3964..5418)
                     /EC_number="3.2.1.26"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /locus_tag="AK725_RS01025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00204"
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="WP_050265476.1"
                     /transl_table=11
                     /translation="MKWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGLL
                     NDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDSHG
                     AYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPADSTD
                     HFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRTAYMM
                     ECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQLQNMD
                     YGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDDKLYQYP
                     VAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSINFDLVNGQ
                     VTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVFSGRVFPHA
                     DQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5471..5668
                     /locus_tag="AK725_RS01030"
                     /old_locus_tag="ERS020212_00205"
     CDS             5471..5668
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AK725_RS01030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ERS020212_00205"
                     /product="hypothetical protein"
                     /protein_id="WP_001147731.1"
                     /transl_table=11
                     /translation="MQAFYVKKEEKLSNDYHKINTGNQLNFYENVKDNEIKDFLTKVSN
                     LFFKEFLMKQSKTINLKLAH"
     gene            5795..7678
                     /locus_tag="AK725_RS01035"
                     /old_locus_tag="ERS020212_00206"
     CDS             5795..7678
                     /EC_number="2.7.1.211"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /locus_tag="AK725_RS01035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00206"
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="WP_001064542.1"
                     /transl_table=11
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVI
                     ENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEAAKQGNWFQRA
                     IRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVV
                     WSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPA
                     FIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATK
                     AILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGA
                     ATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLA
                     SILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAA
                     AKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGV
                     VYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKVAQGNKVKAGD
                     VLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIEVKI"
     gene            7827..8714
                     /gene="scrK"
                     /locus_tag="AK725_RS01040"
                     /old_locus_tag="ERS020212_00207"
     CDS             7827..8714
                     /EC_number="2.7.1.4"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008865 - fructokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scrK"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /locus_tag="AK725_RS01040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00207"
                     /product="fructokinase ScrK"
                     /protein_id="WP_000164302.1"
                     /transl_table=11
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKTI
                     EFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPMYF
                     TTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHYYVA
                     RHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYIAQAA
                     VNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAVAGNGS
                     ATLGNFVLAKEVSK"
     gene            complement(9034..9651)
                     /locus_tag="AK725_RS01045"
                     /old_locus_tag="ERS020212_00208"
     CDS             complement(9034..9651)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /locus_tag="AK725_RS01045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00208"
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="WP_000076185.1"
                     /transl_table=11
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQSK
                     ETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGIVI
                     GCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADFLCM
                     LAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10066..>10254)
                     /locus_tag="AK725_RS01050"
                     /pseudo=""
     CDS             complement(10066..>10254)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /locus_tag="AK725_RS01050"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS30 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GSNKNHNKFIHRWLPQGTKKTTTKEVAFIEKWINNYPKKCLNYKS
                     PREDFWMTNLNLKFSNN"
     gene            complement(10647..10838)
                     /locus_tag="AK725_RS12785"
     CDS             complement(10647..10838)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AK725_RS12785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_000836789.1"
                     /transl_table=11
                     /translation="MKSKEQTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVSN
                     YIYGKAKLTWFEEIFEEY"
     gene            10960..11853
                     /locus_tag="AK725_RS01060"
                     /old_locus_tag="ERS020212_00209"
     CDS             10960..11853
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /locus_tag="AK725_RS01060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00209"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000895292.1"
                     /transl_table=11
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIFH
                     SILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDAKE
                     VKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLDPVN
                     TELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQYGKT
                     RLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIATFDQQ
                     APTIDEIFKLESGVEV"
     gene            11850..13049
                     /locus_tag="AK725_RS01065"
                     /old_locus_tag="ERS020212_00210"
     CDS             11850..13049
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /locus_tag="AK725_RS01065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00210"
                     /product="ABC transporter permease"
                     /protein_id="WP_001245381.1"
                     /transl_table=11
                     /translation="MRNMWVVIKETYLRHVKSWSFFFMVISPFLFLGISVGIGHIQGSS
                     MAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSVLK
                     AVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEAKEN
                     KKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYARMMA
                     LFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISLFMYVV
                     LAAFLGSMVSRPEDSGKALSPLMILIMGSFFGVTALGAAGDNLLLKIGSYIPFISTFFM
                     PFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTFKRALSYK
                     "
     gene            complement(13462..14229)
                     /locus_tag="AK725_RS01070"
                     /old_locus_tag="ERS020212_00211"
     CDS             complement(13462..14229)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498765.1"
                     /locus_tag="AK725_RS01070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00211"
                     /product="membrane protein"
                     /protein_id="WP_000498765.1"
                     /transl_table=11
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALVGIQTQGFKNLPYQE
                     SQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITAKL
                     IGAFIWSLISTSVLLLCIYIILLSTNSNEVQLSTLLSFVGEHFTGFSLTVLSFLLNTIS
                     GILCIYLAISIGQLFNEYRTALAVAAYIGIQIVVGFIEVFFNTSTNFYINSLAGFNDNF
                     YMGASIGIVEELIFIAIFYLGTYYILRNKVNLL"
     misc_feature    complement(14188..14203)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            complement(14246..14941)
                     /locus_tag="AK725_RS01075"
                     /old_locus_tag="ERS020212_00212"
     CDS             complement(14246..14941)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /locus_tag="AK725_RS01075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00212"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000054201.1"
                     /transl_table=11
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTTL
                     IKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYKDF
                     NLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPAARA
                     YILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESGESID
                     QLFRQEFKA"
     gene            complement(14946..15311)
                     /locus_tag="AK725_RS01080"
                     /old_locus_tag="ERS020212_00213"
     CDS             complement(14946..15311)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /locus_tag="AK725_RS01080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00213"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_000119153.1"
                     /transl_table=11
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEAG
                     VNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTHFG
                     YEKEELPGVVSDYIKGV"
     gene            15451..15924
                     /gene="nrdR"
                     /locus_tag="AK725_RS01085"
                     /old_locus_tag="ERS020212_00214"
     CDS             15451..15924
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /locus_tag="AK725_RS01085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00214"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_001203672.1"
                     /transl_table=11
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVE
                     ERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQ
                     SEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15925..17094
                     /locus_tag="AK725_RS01090"
                     /old_locus_tag="ERS020212_00215"
     CDS             15925..17094
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /locus_tag="AK725_RS01090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00215"
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="WP_000802387.1"
                     /transl_table=11
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISFW
                     DNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQDFL
                     EHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKKVAN
                     DFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVISTKR
                     MREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQQMAGL
                     GLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRERGQKAKT
                     QKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            17095..17991
                     /gene="dnaI"
                     /locus_tag="AK725_RS01095"
                     /old_locus_tag="ERS020212_00216"
     CDS             17095..17991
                     /codon_start=1
                     /gene="dnaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /locus_tag="AK725_RS01095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00216"
                     /product="primosomal protein DnaI"
                     /protein_id="WP_000446531.1"
                     /transl_table=11
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEELN
                     RSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAAIK
                     NRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGVGKS
                     FMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILDDIGA
                     EQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEARRVME
                     RIRYLAEETRLEGVNRR"
     gene            17988..18701
                     /locus_tag="AK725_RS01100"
                     /old_locus_tag="ERS020212_00217"
     CDS             17988..18701
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /locus_tag="AK725_RS01100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00217"
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="WP_000140849.1"
                     /sec_met_domain="PF00881 (E-value: 9.7e-23, bitscore: 74.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQS
                     YSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVEGL
                     LISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMALGVP
                     NQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQFGQA
                     EPSSTRKNLEQKKLL"
     gene            18715..20025
                     /gene="der"
                     /locus_tag="AK725_RS01105"
                     /old_locus_tag="ERS020212_00218"
     CDS             18715..20025
                     /EC_number="3.6.5.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="der"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /locus_tag="AK725_RS01105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00218"
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="WP_050120298.1"
                     /transl_table=11
                     /translation="MALPTIAIVGHPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYAT
                     GEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVA
                     RKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENL
                     PNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDG
                     QEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGF
                     AHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLP
                     EMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFV
                     NEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     misc_feature    20080..20091
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.14"
                     /tool="antismash"
     gene            20114..20449
                     /locus_tag="AK725_RS01110"
                     /old_locus_tag="ERS020212_00219"
     CDS             20114..20449
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /locus_tag="AK725_RS01110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00219"
                     /product="hypothetical protein"
                     /protein_id="WP_000400493.1"
                     /transl_table=11
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFYS
                     LFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQELG
                     KSKGGRH"
     gene            20589..20924
                     /locus_tag="AK725_RS01115"
                     /old_locus_tag="ERS020212_00220"
     CDS             20589..20924
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /locus_tag="AK725_RS01115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00220"
                     /product="hypothetical protein"
                     /protein_id="WP_044727721.1"
                     /transl_table=11
                     /translation="MEHLFKMVILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLYA
                     LFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRELG
                     KSKGGRH"
     misc_feature    complement(21454..21466)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.78"
                     /tool="antismash"
ORIGIN
        1 ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgattgct
       61 ggtattatca atcatgaact aggattctag ttttgcagga agtctactac tttccttatt
      121 gtctgtaaat ctactgacct tgttgtttat cccagtcatg gtttctagtt cgggctcaga
      181 gtttcaaagt ggatggtaag agcatcaatt gattgctgag aaggttagta aaacacttga
      241 caagacattt gataaggatg tcagagaaat tccgaccagt cagttttatc aaaaatttgt
      301 agatgagatg ggaaggactt actcaggaaa tttgatcctc caggagctga taactgtgaa
      361 tggagcttat aaagctactt atatcggtga actctctagc aactaatcat tctttaaaat
      421 gatgaccaat aagaggcttg atttggtgaa tcaagtcttt tttctctctt ttactgccat
      481 ttgtgataaa atagtataga acgatttttt acatgaatga taaaacagag gtaaatatga
      541 caatcggtat tgataagatt ggttttgcga ccagtcaata tgtcttgaaa ttacaagact
      601 tagcagaagc gaggggaatt gaccctgaaa aattaagtaa aggactctta ctcaaggaat
      661 tgagtattgc gcccctaact gaggatatcg tgaccttggc ggccagtgct agtgactcta
      721 ttttaactga gcaagaaaga caagaagttg acatggtcat tgtggcgacc gagtcaggaa
      781 ttgaccagag taaggctgcg gccgtctttg tgcatggctt gctgggcatc cagccctttg
      841 ctcgtagttt cgagattaaa gaagcctgct atggggcgac agctgccctc cattatgcca
      901 aattgcatgt ggaaaattct ccggagtcca aggtcttggt cattgccagt gatattgcca
      961 aatatggtat tgaaactccg ggagaaccca ctcagggtgc cggaagtgtg gctatgttga
     1021 ttacacaaaa tccacgcatg atggccttta ataatgacaa tgtagctcag acccgtgaca
     1081 tcatggattt ctggcgacca aattactcga caactcctta tgtaaatggt gtctattcta
     1141 cccaacaata cttggatagt ttgaaaacga cttggcttga atatcaaaaa cgctaccagc
     1201 ttactctgga tgattttgcg gctgtttgtt tccacttgcc ttatcctaaa ttagcgctaa
     1261 aaggcttgaa aaaaatcatg gataagagcc tgcctcaaga gaaaaaagac ctcttacaaa
     1321 agcattttga ccagtctatt ctctacagtc aaaaggtggg gaatatctac acaggttcac
     1381 ttttccttgg acttttgtct ctcttggaaa atacagatag cttgaaagct ggggataaaa
     1441 tcgcccttta tagttacgga agtggagctg tggctgagtt cttcagtggt gaattggttg
     1501 aaggatatga agcttatttg gataaagacc gcttgaacaa gctcaaccaa cgaactgccc
     1561 tatccgttgc agactatgaa aaggtctttt ttgaggaagt aaacttggat gaaacaaact
     1621 ctgcccagtt tgctggctat gaaaatcaag attttgcctt ggttgaaatt cttgaccacc
     1681 aacgccgtta tagcaaggtt gaaaaataat gaagataagt tggaatggat tttctaaaaa
     1741 atcataccaa gagcgcctcg agctgctaaa agctcaggcg ctccttagtc ctgagagaca
     1801 agctagtctg gagaaggatg aacagatgag tgtgactgtg gcagaccagc tgagtgagaa
     1861 tgtggtggga actttttctc tgccttattc gctggttccg gaggtacttg tcaacggtca
     1921 ggaatacacc gttccctatg tgacagaaga accctctgtg gttgcggcgg ccagctatgc
     1981 cagcaaaatc atcaagcgtg caggtggttt tactgcacaa gtccatcagc gccagatgat
     2041 tgggcaggta gccctttatc aagttgctaa tcctaaacta gcgcaagaga agattgccag
     2101 caagaaagcg gagctcttgg agcttgccaa tcaagcctat ccttctatcg ttaaacgtgg
     2161 gggtggggcg cgtgatctgc atgtcgagca gataaaaggc gaaccagact ttctcgttgt
     2221 ttatattcat gtcgataccc aggaagccat gggtgccaat atgctcaaca ccatgctgga
     2281 agccttgaaa ccagtcttag aagaactcag tcagggacag agtctcatgg gaatcctgtc
     2341 caactacgcg actgattctc tggtgactgc aagctgtcgc atcgcctttc gctacttgag
     2401 ccgccaaaag gatcaaggac gagagattgc ggagaaaatt gcgttggcta gtcagtttgc
     2461 gcaggctgat ccttaccgag ctgctactca taataaagga atttttaatg gtattgatgc
     2521 gattttgatt gccactggta atgactggcg tgccatcgaa gctggggccc atgcctttgc
     2581 cagtcgagat ggacactatc aaggtcttag ctgctggacg ctggaccttg aaagagaaga
     2641 attggtcggt gagatgaccc tgcccatgcc tgtagcgact aagggtggct ctatcggcct
     2701 caacccacgt gtagctctca gtcatgatct actaggaaat ccttctgcca gagaattagc
     2761 ccagattatc gtgtccatcg gtcttgctca aaattttgca gccctcaaag ccttggtaag
     2821 tacgggcatc cagcaaggcc acatgaaact acaggccaaa tccctagctc tcctagctgg
     2881 ggctagtgaa tctgaagttg ctcccctagt agagcgcctc atctcagata aaacctttaa
     2941 cctagagaca gcccagcgct atctcgaaaa tttaagatca taaaaactca gacgaatcgg
     3001 tctgagtttt cttgtgttta aatacttttt cctggtaata gtgtaactgg taagaagtaa
     3061 ccagttgtgg cgacttcctt gccttcaatc ttttgcaaga gaagatcaat agtgagacaa
     3121 gcaatctctt ccaaaggttg cttgatagta gccaattgag ggtagtaatt ttcgataaag
     3181 taggtcccat catagccgat gaccttgagc tcttttggga cagaaatgcc caattcttga
     3241 gcgattttaa tgaccagaat agctgtcaaa tcatccgaag caaaaatggc atctggtttt
     3301 tcccgggtca agatattctt gatttccatt tcttttctga cgggagaaaa gtcactggaa
     3361 acattgataa taggagcttt tgggagtacg gatgcaaaac cagcgtggcg cagtccggtt
     3421 ggcgaattgg aattgtcatt ccctgtaatc atgatgatag actgggcacc tgtcttgacc
     3481 aaggtttggg cagcaagaac cccaccagca tagttgtcag aggagacaac agggatgtct
     3541 ggcgataggt ttcggtcaaa ggaaataatc ggcgctgtca cacgattgta gtcttcgatt
     3601 cctaggttgt gactaccaga aatgatgccg tctacctgat tggcttccaa catttcgatg
     3661 tattcgcgtt ccttctcaga atcatgttca ctgttgcaga tgatggtctt gtaaccattt
     3721 ttgaagagtt ggtgttccaa tttatcaatc aattctgcat agaaaacatt ggaaatattg
     3781 gggaaaatca agccgattaa cttagctgat tttccttgca gactacgagc caggttgttg
     3841 ggtttatagc ccaattctcg catggcttca ttgacttttt ggatggtttt ctcagataga
     3901 tacccttttt tattgataac ccgagaaacg gtagtaggac tgacgcctgc aagtttggcg
     3961 acatcagtta gttttgcgac cataatctaa ttcatagtaa gttccagttg ggtttccaga
     4021 tttgatcagg ataccatttt ggtccgcatg tgggaagaca cgaccagaaa atactttttc
     4081 tcctttattg atgaaaattt caaagacaga gttatcgatg aagattgtag cagtagtagc
     4141 ctgattctcg atagggcaag aacgagttgt cccaaattct tgggcatact gttctccagc
     4201 ctggctacga tccactgtca cttgaccgtt tacaaggtca aagttgattg aaagtccctt
     4261 accttcttta tcagcaagta agacaatctc gctctggcta ttagcttcca agttgagttc
     4321 aagttcgtaa gtgttcttgg tttgggaacg gtttgagaag gcttcttcag aagcacgaag
     4381 gtccttaata gcagcgactg gatactggta gagcttgtcg tctttgatag tgagttcctt
     4441 gaccaaagag aaggttcctt ggtggtcaaa acggtcagat gggtaagaaa catctggcaa
     4501 accaagccag ctaactgcta gagcacgccc atcaggagcg ttgaaggctt gagttgcata
     4561 ggcttcgaaa ccgtaatcca tgttttgaag ttgagacaca tctaccattt tggcattttt
     4621 agggtcaaag gaagccccaa tcttatacat atttggaaag atattatcgt agtctagaac
     4681 tttcttatcc aatccttgtg gacagtagag aaggacaggc tgttcctcta caaagaccag
     4741 attaggacat tccatcatgt aggcagtacg atcgttagca aagtcaaggt cgccaactgc
     4801 ttgccagttt gtgtagtcgt tattgacagc cttgtagaga cggacgaagc cttttttctc
     4861 caagtcctgt ccaccgacga cagcatagta ttgaccttta aagttaaaaa tttgtggatc
     4921 gcggaagtgg tcagtagagt ctgctggctg gtcaatcaag atcttgtcaa tctttgtaat
     4981 cttaccctcc ttgtccatca aagcaccgat ttggtatggg tgacggatcc agttttcatc
     5041 gcgaacattt cctgtataaa ataggaataa gttatcgcca aattgcatgg cagaaccaga
     5101 gtaggcaccg tggctatcta atggagtatc tggtaaaact ttgattccag tttctttaaa
     5161 gtgaaccaaa tcatcacttt ctagctgtgc ccaagatttc aaaccgtggg ctgcaccaaa
     5221 aggaaaattc tggtaaaaga ggatccactt gccatcaaag taagaaaagc catttgggtc
     5281 gttgagaagt cctgtttttg gctcaacatg gtaatgagta tgccatggag attgtgccat
     5341 attttccttt atatgttgaa tttcttcttg cgtccaatct tgataaagtc tgtaacgacg
     5401 ctcagttgtc catttcattc attcctccaa aaatcttatc acttttaata gtaactgttt
     5461 tcgataaaaa atgcaagcct tttatgttaa aaaagaggaa aaactatcaa acgattatca
     5521 taaaataaat acaggaaatc aattaaattt ttacgaaaat gtgaaagata atgaaataaa
     5581 agacttttta accaaggttt caaacttatt tttcaaggaa ttcctgatga aacagtcaaa
     5641 aacaatcaat ctaaagcttg cccattaagt ggatagaata ttttttatgc aaaacgcttg
     5701 acatattttt aaaacatgat aaaataatag tcgtaagggc gaataaaatc gctttcaaac
     5761 aagaacaaaa tgttatataa ggagattttt gcaaatgaac aatcaggaaa ttgcaaaaaa
     5821 agtcatcgat gccttgggcg gacgtgaaaa tgtcaatagt gttgcccact gtgcgactcg
     5881 tctacgtgtc atggtcaaag atgaagagaa aatcaataaa gaagtgattg agaacttgga
     5941 aaaagttcaa ggtgctttct ttaactcagg gcaataccaa attatctttg gtacaggtac
     6001 agttaacaaa atgtacgatg aagttgttgt acttggctta ccaacatcat ctaaggatga
     6061 catgaaagca gaagctgcta aacaagggaa ctggttccaa cgtgctatcc gtactttcgg
     6121 tgatgttttc gttccaatca tcccagttat cgtagcgaca ggtctcttca tgggtgtgcg
     6181 tggtcttttc aacgctcttg aaatgccact tccaggtgac tttgcaactt acacacaaat
     6241 cttgacagat acagccttca tcatcttgcc aggtttggtt gtgtggtcaa ccttccgtgt
     6301 atttggtgga aatcctgccg ttggtatcgt tcttggtatg atgcttgtct ctggctcact
     6361 tccaaacgct tgggcagttg ctcaaggtgg tgaagtaaca gcgatgaact tctttggttt
     6421 catccctgtt gttggtttgc aaggttccgt tcttccagcc ttcatcatcg gggttgtcgg
     6481 agctaaattt gaaaaagctg tccgcaaggt tgttccagat gtcattgacc tcttggtaac
     6541 accattcgtg acacttttgg tcatgtctat ccttggactc tttgtcattg gaccagtttt
     6601 ccacgttgtt gaaaactaca tccttattgc tacaaaagcg attcttagca tgccatttgg
     6661 tcttggtggt ttcttgattg gtggggttca ccaattgatc gtcgtgtcag gtgtgcacca
     6721 catcttcaac ttgcttgaag tgcaattact tgctgctgac catgctaacc cattcaacgc
     6781 tatcatcaca gctgctatga cagctcaagg tgctgctact gttgcggttg gtgttaaaac
     6841 aaaaaatcca aaactgaaaa cacttgcttt cccggctgct ctttctgcct tcctaggtat
     6901 tacagagcct gctatcttcg gggtgaactt gcgcttccgt aaaccattct tcctttcatt
     6961 gattgctggt gcaatcggtg gtggattggc ttctatcctt ggacttgctg gtactggtaa
     7021 tggtatcacc atcatccctg gtacaatgct ttatgttggt aacggacaac ttccacaata
     7081 ccttcttatg gtagctgtat catttgccct tggttttgct cttacttaca tgtttggtta
     7141 cgaagatgaa gtagacgcaa ctgcagctgc aaaacaagct gaagtggctg aagaaaaaga
     7201 agaagttgcg ccagcagctc ttcaaaatga aacacttgta actcctatcg tcggtgatgt
     7261 tgtcgctctt gctgatgtca atgacccagt cttctcaagt ggagctatgg gacaaggtat
     7321 cgctgtgaaa ccaagtcaag gcgtggtcta tgcactagct gatgctgaag tttcaattgc
     7381 ctttccaaca gggcacgctt ttggtttgaa aacaagaaat ggtgctgaag ttttgattca
     7441 cgttggtatt gacactgtat ctatgaacgg tgacggtttt gaagcaaaag ttgctcaagg
     7501 taataaggtg aaagctggcg atgttcttgg aacatttgac tcaaacaaaa tcgctgcagc
     7561 tggacttgat gatacaacaa tggttatcgt tacaaataca gctgactacg cttcagtagc
     7621 tccagtcgca acaggttcag tttcgaaggg ggatgctgtg atcgaagtga aaatctaatc
     7681 aatcctctct aatgtgaaaa cgaacaaatg acatgtttgt tcgtttttat tagatagtaa
     7741 gatttacaga ggaaaatcta aaaaatagag acatttagac tttcgaagta tgctataata
     7801 aagaaaataa aaacaagagg tttatcatga caaaattata tggaagcttg gaagcgggcg
     7861 gtacaaagtt tgtctgtgct gtcggtgatg aaaactttaa cgttgtagaa aaaacacaat
     7921 ttccaacaac aactccaatc gaaacaatcg ataaaaccat tgagttcttc tcaaaattcg
     7981 ataaccttgc tggtcttgca gttggttcat ttgggccgat tgatattgac aaaaactcaa
     8041 aaacttatgg ctttatcacg acgactccaa aaccaaactg ggcaaatgta gacttgcttg
     8101 gtgcccttcg tcgcgcccta aacgtgccaa tgtacttcac aacagacgta aacagctctg
     8161 cttacggtga aatggttgcc cgtaacaatg ctggtggtcg tatcgaaaac ttggtttact
     8221 acacaatcgg tacaggtatc ggtgcaggcg tcatccaacg tggtgagttt atcggtggtg
     8281 tgggtcaccc tgaaatgggt cattattatg ttgctagaca cccaatggat attgaaaaag
     8341 agtttaaggg tgtttgtcct ttccataagg gatgtctaga aggttatgca gctggtccaa
     8401 gtttggaagc tcgtacaggt gtacgtgggg aaactattga actcaacaac cctgtttggg
     8461 atgttcaagc ctactatatc gctcaagctg cggttaatgc gacagtgact ttccgcccag
     8521 acgtgattgt ctttggtgga ggggtcatgg ctcaacaaca tatgctggac cgtgtccgtg
     8581 agaaatttac atctcttctt aatggttacc taccagtacc agatgtgcgt gactatatcg
     8641 tgacgccagc agtcgcagga aatggttctg ccacacttgg gaactttgtt cttgcaaaag
     8701 aagtttcaaa ataaagcaca aaatccgctt gggaaaccaa acggattttg tggttgaaaa
     8761 caatattttt gagcctttcc ttaagtgatt acggacggta gcgactttct tcgaaattcc
     8821 atacctaaac tttgagacac taggctcaaa gtttccgaat acctgaaacc attagatttc
     8881 aggtgtttct atcacggcgg aaaggctagg taagtcctcg cctcactatc gaaaaatatg
     8941 catgatttcc ataccaaagt atatttagta tcaagctata gttaatctac gctttaaaaa
     9001 tccacttggg aaaccaaacg gattttttac gtgtcaaagc atttgccaga aaaagtcaat
     9061 aatataggtc agaccgtagg tataaaccac gagggtaaag ggtttggtca gaatgatgat
     9121 ggtcatgtag cgcttgaaac tcatcttggt cagggcagcc agcatacaga gaaagtcagc
     9181 tgggctaatg ggccaaatca tcataaaaat aaagaagcgg tcaaaacgat tgcccttatc
     9241 tagccagccg atgtacttgt cgtaggtgcg cttgctgacg acagactgga caaaggcagc
     9301 tccgtatagg cgcactagat aaaagataat ggcacagcca atcacgatgc cgatatagtt
     9361 gtagatagtc ccgatgatgt gcccgtagat aaagacccca gccaccgagg tcaaggcccc
     9421 tggaatgata gggacgacag tctgtaaaat ctgtaaaaag ataaagagag gtggacccca
     9481 gatgcctgcc tgctggataa aggcagagag ggtttccttg gattgtaaaa tcccagcctg
     9541 ataagcccaa atacagaaaa tcaaactccc aaccccaccg acaatcgatg agatattgat
     9601 aactcgctgc agaaggggag aaacagcttt catttgttta tcctgtgaca tgtaaactcc
     9661 tcatagatag tatatttcta ctataccata ttttggagga gaaaggggga atgagtcttt
     9721 tttgataagg aatagaaagt aaatagccct tcgagactta gaataggtct gtcaactaaa
     9781 ggttatatgc attctaggtt tcgaataatc gcaattccat aaatttaaaa gcattctaag
     9841 tttcgaatag cttatctgag ataattttga ggcattcgcg ctttcgaata gtcatttttc
     9901 ctaaagttta gatgtattct gaagctagaa agactaaaat ctaaaagtag taagagtctc
     9961 tctctgatgg acgtaattta tggctagtat gaatcctttg aattgttagt taattttaat
    10021 attaatcagt tctgaaataa ttactaaata tagttagatg gtgaattaat tattgctaaa
    10081 tttcaagttc aagttagtca tccagaagtc ttctctgggg gacttgtagt tcaagcattt
    10141 tttaggatag ttgttaatcc acttttcgat gaatgcgact tcctttgtag tcgttttctt
    10201 agttccctga ggtaaccatc tatgaatgaa cttgttgtga tttttattag atcctatagt
    10261 ggtgtgcata atagatataa tagattgaaa ctagaatagt acgcatctac ttctaaaaca
    10321 ttgttagaaa tcgatttgac tgtcccgatc tatttgtcct gtttttattt cattttgcta
    10381 tataatcctt agaaaacata tcggacaagc ggttgaattc cgttccgtcc attagtagat
    10441 aaaggattac tccttcttga aatgacagat gaacttgttt cttataaaaa tgttgtctga
    10501 aactattcgc ttttttccag aagttttaga ggaagaaaac tttatgagga aaaaggagtt
    10561 actcaaataa caattcagga ttaaaaatag acagttgagg agcggaaggt ataaattaag
    10621 tttgctactg tataatggat ttatcactaa tactcttcga aaatctcttc aaaccacgtc
    10681 agcttcgcct tgccgtagat atagttactg acttcgtcag ttctatccac aacctcaaaa
    10741 cagtgttttg agctgacttc gtcagtttta tctgcaacct caaagctgta ctttgagcag
    10801 cctacggcta gcttcctagt ttgctctttg cttttcattg agtataaaag tgctccaggc
    10861 catattttac acagcaatag tcttctaaaa atggacaaaa acattgtaaa ggctatcaaa
    10921 aaggagtata atgagtgcaa gaaatttcgg aggtgaaaga tgctagaagt aagaagtcta
    10981 gagaaaagtt ttggatccaa gcaagttttg tttggtattg actttcaagc gcgaccaggt
    11041 cgtattttgg gactagtcgg aaaaaatggt gctggaaaaa caacgatttt ccatagtatt
    11101 ttaaaattcc tagaatatca gggagaaatc ggtctggatg gtcaggatat tcgtcaggag
    11161 acctatgctc ggattggtta tctgcctgaa gaacgcagtc tcatgcctaa attgacagtt
    11221 cttgaacaag ttcgctactt ggcgactcta aaaggcatgg atgccaaaga agtcaaagaa
    11281 aaactccctc aatggatgaa gaggttggaa gtgaaaggaa agctgacaga taaaatcaag
    11341 agtctgtcaa aaggaaatca gcagaagatt cagctcatta ttactctgat tcatgaacca
    11401 gacctgatta tcttggatga gccttttagt ggattggacc cagttaatac agaattgctc
    11461 aaacaagtca tttttcagga aaaagagcgc ggagcaacca ttatcttttc tgaccatgtc
    11521 atgaccaatg ttgaggaact ttgtgacgat attctgatga tccgagatgg ccgtgtggtc
    11581 ttgcacggac cagttcagga tgtccgcaat caatacggga aaacgcgtct ctttgtttca
    11641 agtgaacgaa gcaaggaaga attggaaaat cttcctcatg tcaaacaggt gagcttgacc
    11701 aaacaaggca gttggaaatt gattttggag gatgagagcg ctggaaggga actcttccca
    11761 atcttgactc aaggtcaata tatcgcaaca tttgaccaac aagcgccaac tatcgatgaa
    11821 atctttaaac tagaatcagg agtggaagta tgagaaatat gtgggttgta atcaaggaaa
    11881 cctatcttcg acatgtcaag tcatggagtt tcttctttat ggtgatttcg ccgttcctct
    11941 ttttaggaat ctctgtagga attgggcata tccaaggttc ttctatggct aaaaataata
    12001 aagtggcagt agtgacaaca gtgccatctg tagcagaagg actgaagaat gtaaatggtg
    12061 ttaacttcga ctataaagac gaagcaagtg ccaaagaagc aattaaagaa gaaaaattaa
    12121 aaggttattt gaccattgat caagaagata gtgttctaaa ggcagtttat catggcgaaa
    12181 catcgcttga aaatggaatt aaatttgagg ttacaggtac actcaatgaa ctgcaaaatc
    12241 agcttaatcg ttcaactgct tccttgtctc aagagcagga aaaacgctta gcgcagacaa
    12301 ttcaattcac agaaaagatt gatgaagcca aggaaaataa aaagtttatt caaacaattg
    12361 cagcaggtgc cttaggattc tttctttata tgattctgat tacctatgcg ggtgtaacag
    12421 ctcaggaagt tgccagtgaa aaaggcacca aaattatgga agtcgttttt tctagcataa
    12481 gggcaagtca ctatttctat gcgcggatga tggctctgtt tctagtgatt ttaacgcata
    12541 ttgggatcta tgttgtaggt ggtctggctg ccgttttgct ctttaaagat ttgccattct
    12601 tggctcagtc tggtattttg gttcacttgg gagatgctat ctcactgaat accctgctct
    12661 ttattttgat cagtcttttc atgtacgtag tcttggcagc cttcctagga tctatggttt
    12721 ctcgtcctga ggactcaggg aaagccttgt cgcctttgat gattttgatt atgggtagtt
    12781 tttttggagt gacagctcta ggtgcagctg gtgacaatct cctcttgaag attggttctt
    12841 atattccctt tatttcgacc ttctttatgc cgtttcgaac gattaatggc tatgcggagg
    12901 gagcggaagc atggatttca cttgctatta cagtgatttt tgcggtggta gcaacaggat
    12961 ttatcggacg catgtatgct agtctcgttc ttcaaacgga tgatttaggg atttggaaaa
    13021 cctttaaacg tgccttatct tataaataga agagccttgc gaaagcgagg tttttaaagg
    13081 tgaaaagggt ggaatcacga acctaattat gtacacatta tgtaaacagg ttgcttgaaa
    13141 actcaattgt atagtgaact gaatctggaa taggataata ttacttctaa aacattctta
    13201 taaattgatt tgaattccaa aatcccatcg ttccgttctt atttcatttt gcgatatagt
    13261 gaaaggaaat aagtcagctc acaaaaaacg catattacca aggttcttat gaactgcccc
    13321 ccaaaagtta gacagaaaaa atctaacttt tggggggcag tacatattca acacctgata
    13381 ctatgcgttt tctaatttta aagacttttt gcctggtctc ttttgttcta tgagtatgtt
    13441 acatatctag gtaaaaatta tttaaagcaa attaacctta tttctcaaga tgtagtaggt
    13501 tccgagataa aagatagcta tgaatatgag ttcttcaaca atgcctatgc ttgctcccat
    13561 atagaaatta tcattaaatc ctgcaagtga attaatatag aagttagtac tggtattgaa
    13621 gaagacttca ataaagccaa cgacgatttg gataccaatg taggctgcaa cagcgagtgc
    13681 tgtacggtat tcattgaaca gttgtccaat ggaaatggcc aagtagatgc agaggattcc
    13741 tgaaatagta tttagtagga aggataagac agtaagacta aagccggtaa aatgttctcc
    13801 aacaaatgac agaagagtag aaagttgaac ttcattagaa tttgttgaca ataagataat
    13861 atagatacat aggagtaaga cagaggtgct aatcaatgac cagataaagg caccgattag
    13921 tttggctgtg atgatatggt gttcagaaac tggcaaggtc aaagtcagat agccttgtcg
    13981 gtcgtagaca ctacctttga agcgtttaat aatcaagaaa atggttgaaa tcgcaagtgt
    14041 aagcatcaag ccaccaaaga ctgtagctag aaaaagtagc atagtagcct gactttcttg
    14101 gtaaggtaga tttttaaagc cttgtgtctg tattccgacg agggcagaaa ggactagcac
    14161 ggctgcgtag agggctaaat accacttgtt aacattttta aattcgtagc gaactaaatt
    14221 ccaaaacata aataatctcc tttgcttagg ccttaaattc ctgacggaag agttggtcaa
    14281 tggattcacc tgactcgtag cgaatatcat ctacatttcc ttgacggacg acttttccgt
    14341 cttttaggaa gacaatttca tccaagattg gctcgatatc agaaatcaag tgggtagaaa
    14401 tcaaaacggt agaagttggt gagtagttgt tgataatggt attgaggata taagcacgtg
    14461 ctgctggatc caccccacca atgggttcat ccaaaacata gagacgagca tcacggctca
    14521 taaccaaaat cagttgaacc ttttctttgt ttccttttga tagtttcttg agacgactat
    14581 tttcatcaat gcccaggtct gcaagtagat gatgggcgcg ttcaagattg aaatctttat
    14641 agaaggtctt gaagtaggtt agggcttctt tgaccttcat ttgctcattg agataggtcg
    14701 tatcaggcaa ataagctaca acggccttgg ttgctgggct tgggtccatg tcgttgatga
    14761 ggacacgtcc ttgatctggt tgtaagaggc cattaattag tttaatcagg gttgtttttc
    14821 ctgagccgtt tggcccaaga aggccgacaa tttttccagc tggaatgtca agagaaacat
    14881 tttcaagggc tggtgttgct ccatatgatt tggatacatt ttcaaatgct agtaatgaca
    14941 taggcttaaa ctcctttaat ataatcactg actacgcctg gtagttcttc tttttcatag
    15001 ccaaaatggg tcatggagga aacgaagtgt tccaattctt cttctgataa ttgtttgcgt
    15061 gactgggcga ttagctcctt atccttagtc acaaatcgtc cagttgttcg cttgctgtag
    15121 acaaatcctt ctcgttcaag gtctgataag gctctttgga tggtattggg attgacacca
    15181 gcctcactag ctagctccct cacggttgga agttgttgat tgggttccag tgtatgggaa
    15241 acaatctgaa gcttgatttt ctccataatc tgtaaataga tgggtttttt gttgtcaaat
    15301 gtccaggaca tcttagtctc ctttctctta cccttttgtc ttaattaaat aatacaacaa
    15361 aacaaaaaac ttgtcaagca aaaagaagaa ttgttttggg aatcgcttaa aaaatggtat
    15421 aatgaaaaga aaacgataag gagggaaagg atgcgttgtc caaaatgtgg ggctaccaag
    15481 tcaagtgtta tcgatagtcg ccaagcagaa gaagggaaca ccattcgtag aagacgagag
    15541 tgcgacgagt gccaacaccg ttttacaacc tacgaacgag tagaagaaag aaccttagtg
    15601 gttgttaaaa aagatggcac acgggaacaa ttctccagag ataaaatctt taatgggatt
    15661 atccgctcag cccagaaacg tcctgtgtca agtgatgaaa tcaacatggt agtcaatcgt
    15721 atcgaacaga aactccgtgg tcgaaatgaa aatgaaattc aaagtgagga cattggttca
    15781 ctcgtcatgg aggagttggc tgaattggac gagattacct atgtacgttt tgctagtgtc
    15841 tatcgtagtt ttaaggatgt cagtgagtta gagagcttgc tccaacaaat cacccagtcc
    15901 tctaaaaaga aaaaggaaag ataaatgaag ccaattgacc gtttttctta tctaaagaat
    15961 aatcgggtgt cgcaagatac ctcatctctg gtacagtgct acctcccgat tatcggtcag
    16021 gaggcactga gcctttatct ttatacaatc agtttttggg ataatggtag aaaggaatat
    16081 cttttttcaa gtatcctcaa tcatctcaac tttgggatgg atagactgat aaaatcattg
    16141 aaaatcttat ctgcttttaa tctcttgacc ctctatcaaa agggggatgt ttatcagcta
    16201 gccctccatg ctcctctatc tagtcaagac ttcttggagc atcctgttta tcgcagactc
    16261 ttagagaaaa agattggcga ctctgctgtg gaggatttga aagttgaaag tgctgatggt
    16321 gaagaaatac ctgtctcact caatcaagtc tttccagaat tggcagaact aggcagtcaa
    16381 gaagaccttg gtctcaagaa gaaagtggcc aatgattttg acttggaaca ttttcgccag
    16441 ctgatggctc gagatggact tcgttttgcg gatgagcagt ccgatgtctt aaacctcttt
    16501 gctattgccg aggagaagaa atggacttgg tttgaaacct atcaattggc caagtcaaca
    16561 gctgtttctc aggttatttc aaccaaacgc atgcgtgaaa aaattgctca aaaaccagtt
    16621 tcctctgact ttagtcttaa ggaaacaacc attatcaaag aagccaaaag taaaactgcc
    16681 ctgcagttct tggcagaaat caagcaaaca cgcaagggaa ccattaccca aacagaaaga
    16741 gaactcttgc aacagatggc tggcttgggc ttgctggacg aagtcatcaa tatcattctt
    16801 ttattgacct ttaataaggt cgattcggca aatatcaatg agaaatatgc catgaaggta
    16861 gccaatgact atgcctatca aaagattcat tcggcagaaa aggcagtctt gcgcatccgt
    16921 gagcgaggac agaaagcaaa aacacaaaaa cagaatcaga ctgccccagt aaaaaccaat
    16981 gttcctaaat ggagtaatcc tgaatataag aatgaaacca gcgaggaaac tcgtctggaa
    17041 ctagaacgta agaagcaaga actattagct cgattagaaa aaggaggaga ttagatggaa
    17101 agtgtcggag acgtactcaa acgtcaaccc agccgttttt attatcaaga tttggtccag
    17161 aaaatcatga aggaccctga tgttgcggct tttatccagc aagaatcctt gactccagag
    17221 gaattaaatc gcagtatctc caagtttaat cagtacatca ccgagcgtga caagtttctc
    17281 cgtggggata cggattatat tgccaaaggc tacaagccga ttttggttaa gaatcatggc
    17341 tatgcagatg tttcatatga agaaactcct gagctaatcg cggctgaaaa agaagcggct
    17401 attaagaacc gtctcaagtt aatcaatcta ccagccagtc tcaagaaagc tagtttggct
    17461 caagttgact tggatgattt ggggcgctta ccagtttttg aaaagctact agccttcgtg
    17521 gagcaatatc cagctattcg aaaaggtctt tacttatatg gagactttgg tgtgggtaaa
    17581 agtttcatgg tggcggcctt agctcatgat ttatcagaaa aacgtggtgt ttcatcaact
    17641 ctcctccact atcctagctt tgtcattgat gtcaaaaatg ctatcagtga tggcaatgtt
    17701 aagaccttgg tggatgagat taagctgtct gaggtcctga ttttagatga tattggcgcc
    17761 gagcaatcaa ccgtttgggt gcgtgacgaa atcctgcagg tcattctcca atatcggatg
    17821 caggaaaatt taccgacctt tttcacatcc aacttcaact ttgaagattt ggagaagcat
    17881 tttgcgaaag tgaaacatgg aaatgacgaa acctgggaag ccagacgggt catggaacgc
    17941 atccgttatt tggctgagga gactcgttta gaaggagtaa accgtcgatg acagaaacca
    18001 ttaaattgat gaaggctcat acttcagtgc gcaggtttaa agagcaagaa attccccaag
    18061 tagacttaaa tgagattttg acagcagccc agatggcatc atcttggaag aatttccaat
    18121 cctactctgt gattgtggta cgaagtcaag agaagaaaga tgccttgtat gaattggtac
    18181 ctcaagaagc cattcgccag tctgctgttt tccttctctt tgtcggagat ttgaaccgag
    18241 cagaaaaggg agcccgactt cataccgaca ccttccaacc ccaaggtgtg gaaggtctct
    18301 tgattagttc ggtcgatgca gctcttgctg gacaaaatgc cttgttggca gctgaaagct
    18361 tgggctatgg tggtgtgatt atcggtttgg ttcgatacaa gtctgaagaa gtggcagagc
    18421 tctttaacct acctgactac acctattctg tctttgggat ggcactgggt gtgccaaatc
    18481 aacatcatga tatgaaaccg agactgccac tagagaatgt tgtctttgag gaagaatacc
    18541 aagaacagtc aactgaggca atccaagctt atgaccgtgt tcaggctgac tatgctgggg
    18601 cgcgtgcgac cacaagctgg agtcagcgtc tagcagaaca gtttggtcaa gctgaaccaa
    18661 gctcaactag aaaaaatctt gaacagaaga aattattgta gaaagtgaga aattatggcc
    18721 ctaccaacta ttgccattgt aggacatccc aatgttggga aatcaaccct atttaatcgg
    18781 atcgctggtg agcgaatctc cattgtagaa gatgtcgaag gagtgacacg tgaccgtatt
    18841 tatgcaacgg gtgagtggct caatcgttct tttagcatga ttgatacagg aggaattgat
    18901 gatgtcgatg ctcctttcat ggaacaaatc aagcaccagg cagaaattgc catggaagaa
    18961 gcagatgtta tcgtctttgt cgtgtccggt aaggaaggaa ttaccgatgc agacgaatac
    19021 gtagcccgta agctttataa gacccacaaa ccagttatcc tcgcagttaa caaggtggac
    19081 aaccctgaga tgcgaaatga tatctatgat ttctatgccc tcggtttggg tgaaccactg
    19141 cctatctcat ctgtccatgg tatcggtaca ggggatgtgc tagatgcgat cgtagaaaat
    19201 cttccaaatg aatatgagga agaaaatcca gatgtcatta agtttagctt gattggtcgt
    19261 cctaacgttg gaaaatcaag cttgatcaat gctatcttgg gagaagaccg tgttattgct
    19321 agtcctgttg ctggaacaac tcgtgatgcc attgataccc actttacaga tacagatggt
    19381 caagagttta ccatgattga tacggctggt atgcgtaagt ctggtaaggt ttatgaaaat
    19441 actgagaaat actctgttat gcgtgccatg cgtgctattg accgttcaga tgtggtcttg
    19501 atggtcatca atgcggaaga aggcattcgt gagtacgaca agcgtatcgc aggatttgcc
    19561 catgaagctg gtaaagggat gattatcgtg gtcaacaagt gggatacgct tgaaaaagat
    19621 aaccacacta tgaaaaactg ggaagaagat atccgtgagc agttccaata cctgccttac
    19681 gcaccgatta tctttgtatc agctttaacc aagcaacgtc tccacaaact tcctgagatg
    19741 attaagcaaa tcagcgaaag tcaaaataca cgtattccat cagctgtctt gaacgatgtc
    19801 atcatggatg ccattgccat caatccaaca ccgacagaca aaggaaaacg tctcaagatt
    19861 ttctatgcga ctcaagtggc aaccaaacca ccaacctttg tcatctttgt caatgaagaa
    19921 gaactcatgc acttttctta cctgcgtttc ttggaaaatc aaatccgcaa ggcctttgtt
    19981 tttgagggaa caccgattca tctcatcgca agaaaacgca aataaaaaag tagaatctgg
    20041 aatgacagtt ccggattttt ttgatataat aaaataatag aaaacgctat caaaagaagg
    20101 ggggatgtcg gtgatggaac atttgtttaa attcttactt ttagcaccgt acttttattt
    20161 tgataactgg attgaaaagg ccaacagaaa tagtaagttt tttccaattt tttattattt
    20221 ttactggttt tacatcccct tctattctct ttttagcctt gcttggacag ttgtttcagt
    20281 tctgtttttc aataccgtct tgagaaatgt gacagatatc aagttatggg gcatttggtt
    20341 tctttttatt ctgctagcta ttggtatgaa ttggttaact tattcctgtt tcaaagaaat
    20401 gtttcgcttg agacaggaac tagggaagtc taagggtgga aggcattgat ttatatcggt
    20461 ttctatttgt aggaggtggc ttatggtacc tctaaaatca tttattacac gctattccaa
    20521 ggtttatatt ggtaataaca tttaatagaa cgaaactaaa aaaaacaatt taaaaaagga
    20581 ggcttgtgat ggaacacttg tttaaaatgg taatcttatt accctgtttt tactttttca
    20641 gctggattga caaggataat agagaaagta aatttttccc aattttttac tatttttact
    20701 ggatttacat caccctctat gctcttttta gccttgcttg gacagttttt tcagttctgt
    20761 ttttcaatat cgtcttgaga aatttgacag atatcaagtt atggggtatt tggctattat
    20821 tactacttat cgcttttgct agtgattggt tagcctatgt ctttttcaaa aaaatgattc
    20881 gcttgaggcg ggaactaggg aaatctaaag gcggaaggca ttgatttata ctcttcgaaa
    20941 atctcttcaa accacgtcaa cgtcgccttg gattatatat gtaactgact tcgtcagtct
    21001 tatctacaac ctcaaagcag tgctttgagc aacttgcggc tagtttccta gtttgctctt
    21061 tgattttcat tgagtattat attactttct atttgtagga ggtggcttat gaagattcct
    21121 ctcttaactt tggcaaggca taaatttgtt tatgtcttac ttactttgct ttttcttgct
    21181 ttggtttatc gtgatgtttt gatgacttat ttcttttttg atattcatgc gcccgatcta
    21241 gctaaattcg atggacaagc aattaaaaat gacttattaa aatcagcatt agattttcgt
    21301 attctccagt tcaatctagg tttttatcaa tcatttatta ttccaatcat cattgttttg
    21361 ctaggttttc aatatattga gctgaaaaat aaagttttac gattgagtat tggaagagaa
    21421 gtgagctatc aagggttaaa aagaaagttg actttgcaag ttgcaagtat cccttgtttg
    21481 atatatttag tgactgtgct gataattgca attataacct atttccttgg gactttttct
    21541 cctcttggat ggaattctct attttctgat ggaagtggtt tacaaagact cctagatgga
    21601 gagataaaaa gctatttgtt ctttacttgt gtcctactaa tcggtatttt catcaatgca
    21661 atctattttt tacaaatagt tgattatgtg gggaatgtga ctcgttcgg
//
