LOCUS       NZ_CP012159            17922 bp    DNA     circular CON 02-MAY-2024
DEFINITION  Chondromyces crocatus strain Cm c5 chromosome, complete genome.
ACCESSION   NZ_CP012159
VERSION     NZ_CP012159.1
KEYWORDS    RefSeq.
SOURCE      Chondromyces crocatus
  ORGANISM  Chondromyces crocatus
            Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae;
            Chondromyces.
REFERENCE   1  (bases 1 to 11388132)
  AUTHORS   Zaburannyi,N., Bunk,B., Maier,J., Overmann,J. and Mueller,R.
  TITLE     Genome analysis of myxobacterium Chondromyces crocatus Cm c5 reveals
            a high potential for natural compound synthesis and the genetic
            basis for the loss of fruiting body formation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11388132)
  AUTHORS   Zaburannyi,N., Bunk,B., Maier,J., Overmann,J. and Mueller,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2015) Department of Microbial Natural Products
            (MINS), Helmholtz Institute for Pharmaceutical Research Saarland
            (HIPS), Campus E 8.1, Saarbruecken, Saarland 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Newbler v. 2.6, HGAP SMRTPortal v. 2.2.0
            Assembly Name                     :: Cm_c5_Newbler_HGAP3_v13
            Genome Coverage                   :: 366x
            Sequencing Technology             :: Illumina, PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001189295.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 07:18:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,280
            CDSs (total)                      :: 8,172
            Genes (coding)                    :: 8,124
            CDSs (with protein)               :: 8,124
            Genes (RNA)                       :: 108
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 96
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 4 of 48
            Pseudo Genes (incomplete)         :: 44 of 48
            Pseudo Genes (internal stop)      :: 3 of 48
            Pseudo Genes (multiple problems)  :: 2 of 48
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:43:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6938370
            Orig. end                         :: 6956292
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012159.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..17922
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="24"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..17922
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..17922
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:12922](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..12922)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(203..218)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.61"
                     /tool="antismash"
     misc_feature    323..336
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            705..1520
                     /locus_tag="CMC5_RS25335"
                     /old_locus_tag="CMC5_051400"
     CDS             705..1520
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /locus_tag="CMC5_RS25335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_051400"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_050432828.1"
                     /sec_met_domain="Abi (E-value: 2.1e-11, bitscore: 42.9,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGGKSATVKQGVILWAGGALGGVAVLPYAFDLQRDALAKSSVAS
                     LGLPTLAAIAAGQTAVLMAIAVAVGLRAARSVGLRAPVSEALATRQPVRDVVHPFVGPA
                     LGLGLLGAVLMTILDLFVFLPALPALREAGKPMIEQFVPWKAALASLYGGISEEILTRL
                     LLLSGIAFLLRAALRRRDVPPQPAVMWTAIVVSAVLFGLGHLPATAAIVPLSGLVIARA
                     VLLNAAIAIPCGWLFWKHGLESAMLAHWLADIVIHILVPALTVAGVLAV"
     gene            1522..2523
                     /locus_tag="CMC5_RS25340"
                     /old_locus_tag="CMC5_051410"
     CDS             1522..2523
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="CMC5_RS25340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_051410"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_050432829.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.1e-17, bitscore:
                     62.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDDDRHLTRLILESFKTDDLDALCKDADLSPEQLQGLRDAFVSA
                     GAARIREIVQPSTWHQVGVTFDGLGLQRPLFFTGRFLEQVRTWLDDRTIDRFSFLDKSP
                     GLRLRFRMLRADFPERLSTFLQTCADEGELSGWVRRAYEAEVHQFGGEVGMDLAHEFFT
                     TESLAVLGHRALHLTGHASLSSTEFSLLLLHDLFQHLVEDRWELWDLWANLALADRSLT
                     LDDAERDDAIALAERARDAIVEILDARPSLLHRLTDPERALLPPYRDATHALAARLRAA
                     RDDGQLSHGLRQILPFWIVFHWNRMGFDADHQRRLAFVMAHLLDPKRAEPPR"
     gene            2520..5075
                     /locus_tag="CMC5_RS25345"
                     /old_locus_tag="CMC5_051420"
     CDS             2520..5075
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS25345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_051420"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_050432830.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.9e-12, bitscore:
                     45.0, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPSSPPAPRAPFSAQWFPLVLLRVPGVPRSHLATLGYHATLTQR
                     RAALAARAPLETAARALADRLHPLVPRVDDRHARRPLLAARRALFKLEPLPEGAWRDTV
                     RALDPALHDDLEAWRLQHATHITHLDRCDALFDEDAATSDRALWELLASKHLVAGLALL
                     NPSLSAHLARIPRCPLAELGVDDRKAIVQAFRYLLRAAMKPTPNGHLAGTFLAQIAPTP
                     APPPQDLGMRTTEFQLSRLVTDRLASVLLEKPAFRDHVSAHVSPCAFEEDGVVWVLHTD
                     PETGRERYQEVPEASALLPHLDQASWGCPSPCAHWGEKLTRATRDRLIETGFLQLSWTL
                     TEETTADDLHAIAQALHPSTEEAPELRPWLAFSQAIQQPLSDLQNAETDEQRHAALGTL
                     HSLLAPDPEQSTEGKTPLLGFDDAAGDARLHVPEHDLAPFLAEVALYGAGYLLPALLPE
                     EQALLALHHQLYPDAPSAPLLHFHRDYLRFCEAKRLGRNHFANLRSLGKHLDLPATDDP
                     AAPFHQGLLDAITRAERGEAHYRPDLSALSRWDTATRTRESLRFAPAPPGPAGPRFHLT
                     LWGGDRMSLFPRYLRRFPSTALTEPFRAWMAQWPAVVDMYGAFNKNPDLRPLTTARALH
                     IPGCPAPVASPSAAFIEPRALDVTRATGRLTLVERATGRPVDPVFLGVSGPHTRPGFAQ
                     FLDHLSGHRTSLLELLFRALNRIVGERIQRASAQVERLPAIVLGDHVLLASELFLVPVA
                     SLPLPRGPVDRAAFFRFHDWLADHGLPLRAQVRVNQRDPLWLDLAHPAGIQNLARLVHG
                     HTVCLVSPPLLDDDALWLRGLDGSYEVELGAEFIAGTAI"
     gene            complement(5001..7136)
                     /locus_tag="CMC5_RS25350"
                     /old_locus_tag="CMC5_051430"
     CDS             complement(5001..7136)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03975.1"
                     /locus_tag="CMC5_RS25350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_051430"
                     /product="RiPP maturation radical SAM C-methyltransferase"
                     /protein_id="WP_156338862.1"
                     /sec_met_domain="TIGR03975 (E-value: 2.5e-154, bitscore:
                     513.8, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-12, bitscore: 47.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIRISGLGSDKARVRAVPDGGKRACLVVMPFTSSWMPAMGASLL
                     KATLLQAGIATDLYYGAPDFFRHFTKGLPVEEALLDYNILASFNNLGDLFFADTLWGDR
                     SERVRHQIERIADIPNPNFSRERFARSVERIRGYLDGAAGYLERCLGARDWGAYDVIGF
                     SSTFSQNVACLTLARAIRARHPEVHIVFGGANCEGDMGVQLLRSFPYVDTVIQGEADTA
                     LPRFIERLRAGRATDDIPGIVFRKGGDVLRGAAVEPLDAMDSLPFADFSDYFEQMPAPI
                     LAHLRERREIAVPLETSRGCWWGAIQHCVFCGLNSATMRFRSKSPERALEETLAMRDRH
                     GVDYIYVVDNIIDLRYLRTFLPRLEGEGLRLFYETKSNLEEEDVHQFARAGVRLIQPGV
                     ESLDSAVLKLMKKGVKAYHNLEVLKWCSTYGVKPLWLYLYGFAHEPVEGYLRVIELIER
                     LVHLEPPKGPNPVLMDRYSPYFTQREALGFRNIRPLAGFELSYRGLDDEERFNLSYHFH
                     FDLPQGSPPYEKALLRAIEHWITAHRAGARFYQFKGERTTLLVDTRRAEPQAFLLSGVG
                     HRIHDHLRRAHGRAAIVEAWASASEAAALLSFSFTDLYLVHVAQALGAEMIASPEREEE
                     LDAFLAGLVERWIAIHVDDRWLGLSVDCTDEGEAARFGLVDVMRRLDVEAGGSDRRSSD
                     ELRAELDLVAAVESAEP"
     gene            complement(7248..7643)
                     /locus_tag="CMC5_RS25355"
                     /old_locus_tag="CMC5_051440"
     CDS             complement(7248..7643)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS25355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_051440"
                     /product="hypothetical protein"
                     /protein_id="WP_050432832.1"
                     /transl_table=11
                     /translation="MDKILEFQQSILNDPTARQALAANPAEYLKLRGIPVPAGTQLPNN
                     IPLEKIENRVSEVKDRLSKRGIAVDFKATTRTDSQKVLSDVFKDELWGAKRAGAGPAAL
                     MRDAEQQLPGETATVAVMAAVVLVVVV"
     misc_feature    7710..7728
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            complement(7745..9823)
                     /locus_tag="CMC5_RS25360"
                     /old_locus_tag="CMC5_051450"
     CDS             complement(7745..9823)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03975.1"
                     /locus_tag="CMC5_RS25360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_051450"
                     /product="RiPP maturation radical SAM C-methyltransferase"
                     /protein_id="WP_050432833.1"
                     /sec_met_domain="TIGR03975 (E-value: 1.6e-170, bitscore:
                     567.3, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.8e-14, bitscore: 52.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEQKAALKVALVYPPYGPAGLPSLGLGLLSAGIQQRGFACRTFH
                     WNLDVVTAMPGEHLEEKLRAYRLLNSRPMLPFNEWVFTRVLFGEREAMREEEARRLLDE
                     HFAGREIRYLRREHILHLRERASDLVEEMVDRLSPFDVIGISSTFFQNVAALALARRLK
                     ARWPEKQVVLGGANCEGEMGKALLEQFPFVDVVFSGESDSSFADYVERLSQGLSVPEHD
                     GIYARRGKRSLLAVQGAPPLFDLDGLPIPDFDDFVEQRGRLGIGEFEALCLPLESSRGC
                     WWGAKQHCTFCGLNGGGMVYRQKSRDRFCAEIEAIVARYGTRFLFMTDNILSMKYYGEF
                     AEWAKARQLGVNFFYEIKANVSRSQVQRLADAGINAVQPGIESFNSNVLALMSKGTTGI
                     QNIAFLKYAREFGVLPVYNILAGFPGEDPADYERTATELPKLFHLKPPNSVPEIEYHRF
                     SPYHQAPERYGIKLRPSHKYAQLYPFPEEVLRRMAYFFDRDDEGAEVPRPYLEPLRHEV
                     RRWHEHYREEECQLTWRRSGQDIVIDDRRPGFPRRLYRLKDHAASLIELLDAPKALKHL
                     LVEAPEASKKTPLDGDGDDASAAQETGPSLDAENDRDASDALLDLLFGLAPALPTAPDV
                     EEEIIAWSRAEFSSDPDGALRQLVGRGLVYAEDGRYLSLSVAEDRRDVVAEWMRLGV"
     gene            complement(9816..10853)
                     /locus_tag="CMC5_RS25365"
                     /old_locus_tag="CMC5_051460"
     CDS             complement(9816..10853)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="CMC5_RS25365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_051460"
                     /product="radical SAM protein"
                     /protein_id="WP_050432834.1"
                     /sec_met_domain="Fer4_12 (E-value: 2.4e-05, bitscore: 23.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.6e-10, bitscore: 40.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIETIVLHYTDRCNIECAHCCVSSGPKRTTKFEPAAARDLIQQAA
                     ALGIGAVKFTGGESLLFPEEILELTRLAGSLGLEVGVVTNGFWAPTVEAGKAFLEPFVA
                     SGLRELDVSVDVWHWKFLDPGQVGHAIAAARSFPELLVRMYRVLKADESPTDPAFYAAY
                     GLDLEALRFESCNANDMLRRRLDGAANGVTVRWTYASRIGRAKSLPLADTRTVPVAEVA
                     PARCTEVTMAPIAYPDGTLYACCSGKVPRPLVAGNLRETSLAELQGRMERNALLQFIAT
                     FSPKELHDALVARGVELPKNCDSVCHICKSALSKVDDALLQEVATEEWNRNVLSQLLGS
                     EILHG"
     gene            complement(10850..12922)
                     /locus_tag="CMC5_RS25370"
                     /old_locus_tag="CMC5_051470"
     CDS             complement(10850..12922)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03975.1"
                     /locus_tag="CMC5_RS25370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_051470"
                     /product="RiPP maturation radical SAM C-methyltransferase"
                     /protein_id="WP_050432835.1"
                     /sec_met_domain="TIGR03975 (E-value: 2.3e-158, bitscore:
                     527.2, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 9.7e-12, bitscore: 44.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAEAPREKRVCLVVMPFTPVVMPGLGVSTLKATLAQAGIASDIY
                     YAALDFFRVFTDGIDHYDAIFDYELIAVSYDLGNVFFANALWGGCLDDVRKEVMSLRDV
                     DNPSIAAEDIAQGVERILRYVEGAGEYVERCYRARDWRQYDIVGFSSTFSQNVGSLALA
                     RLLKERHPELCIVFGGANCEGDMGAEMLRSFPQVDVVIQGEADFSFPRFIEAQRQGLST
                     ADIPGIVFRDGGEVRTGPESVPLQAMDALPMPDFDDYFEQLPPVVQHLRASGRLSLPFE
                     TSRGCWWGAIQHCVFCGLNSSAMGFRSKSPERALEEIRWLGERHRVTQFYAVDNIISKR
                     YFKEVLPKLEEDGLNIFYETKSNLSEEEVYQFARSGIRRIQPGIEGLSSEILELMKKGV
                     KGYRNVELLKWCAMGGVTPVWFYLYGFPNEPHAPYFRDVALLPRLVHLPPPRSPNPVLM
                     DRFSPIFTRREEYGYKNVRPLPRANLYYRGLSEEGRFNISYHFAAELPQGNGLPYQERL
                     WIEVRGWQNRYVDGARFYQFQGVRTTLLVDTRRDERRAYLLSGDGHWLHDGMRRARTRE
                     NLTERWRKRPSADAALAFSLDDLYLVAIAGAFAAETIPSPETEADLDGWLEALVERWIV
                     LPMDDRYLALAVDCTSAQEAEKFGLPVAARRAPSGGRDAEEIRRLPILQGEEASP"
     gene            complement(12922..13989)
                     /locus_tag="CMC5_RS25375"
                     /old_locus_tag="CMC5_051480"
     CDS             complement(12922..13989)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="CMC5_RS25375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_051480"
                     /product="radical SAM protein"
                     /protein_id="WP_050432836.1"
                     /sec_met_domain="Fer4_12 (E-value: 9.8e-09, bitscore: 34.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.4e-15, bitscore: 56.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.7e-06, bitscore: 25.4,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTDRKIELGLMYSRTCNIACKHCGILSSPENKETMRFEDAKRFI
                     REATEIPVIRKVNFTGGEPFLFQKEHAEMFEICKAAGLKTRVVTNGFWAKNFDRGLEFL
                     SRMKEAGLTELNFSADKYHLEFQDPKILRNALECTRRLDFLRILGYVHPGEGDPLDALS
                     DLYGLPREDLVDLRKLLDAREDLQNWKHKILVNAAGLIGLGRAAEYPEELRYFPMSVFP
                     SEGCHEIVNKPVIYPDGDLQACCCAGGKIAGFTVGNLHKESLATLVERMTERAHFKFIN
                     DHGPKELYLAVGRSRQDRKRRPGHTSICEVCVRACDGVSAQEMDEIAERASFQKAFAWL
                     LPEATTSATPAAEVE"
     misc_feature    complement(14088..14102)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     misc_feature    14237..14253
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.21"
                     /tool="antismash"
     gene            complement(14699..15631)
                     /locus_tag="CMC5_RS25385"
                     /old_locus_tag="CMC5_051500"
     CDS             complement(14699..15631)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS25385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_051500"
                     /product="hypothetical protein"
                     /protein_id="WP_050432838.1"
                     /transl_table=11
                     /translation="MAITLSPAQQAVLVQTRALDTPAQFEALLAAARPEIDQVVQEVMA
                     PAQAIDDILIELRDLYLTVIEQSAALATVGYGQGRREAFCAAIQLLDTGHLWFGEGART
                     GAYRTLNVEDLVALSRPYRARLKAYGAQAFVFEPKVAALFADVNRSRTVAEEIADLRVL
                     VNEARARQARLVTVGVTEAFLVEGEELLRTAESRDLLGILGIRHQDEAILLRNEILTYA
                     VMLGREARAAGVNACFHEPKVRVRFEGASFRQALRRLRPKRRKQDGEVDEVDEVQPPGS
                     CGVPVATSPTTSPTTSARSFEPAPDSVAG"
     misc_feature    complement(15617..15619)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15687..15702)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    15730..15745
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    15731..15747
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.48"
                     /tool="antismash"
     misc_feature    15735..15749
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.75"
                     /tool="antismash"
     misc_feature    complement(15736..15749)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.28"
                     /tool="antismash"
     misc_feature    complement(16628..16641)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
ORIGIN
        1 agcgccgccc agcgcgaaag ccgagccctc cagtcaccac caggagcact ccgaagacga
       61 gcgccgcgcc cctcgggaag ccgtcgagca ggaacagcgc cagcagcgcg acgagccctc
      121 ccagtgccgc acagaacagc gcgtccccac ccccacgcag gtgctgcttc agtgcctgct
      181 ctcgacgccg accccgttct cgaatcgtct cgacctctgc cttggtgggc aagcgcatct
      241 cgcggcggaa ttcatccacg cgcggaatct accccagccc tgtcgacatc ggtgctcgac
      301 gggagctccc ggtccggggc gatggatcgg gtgcaaatcc gcaccaagcg gaatccaccg
      361 atcgacctgc cttgttgaca cctccagctc gcgctctcgc ggtgcgatca gcgcccgcgt
      421 caccaccgca acccgacagg tcaccgcacc gccatcgcac gcgatgacga cctcgcgctg
      481 cggagcgacc cgcatcgacc gtcgaaacgg agggcagcgc ccttgcatcc cttccttgat
      541 gatgtcagtc gcagaccgac ggctggaaac cgcgactcga ccatgggcag cggagcgacc
      601 gatccatgga tccgacgatc acgctgcggt gtgcaccgac gcatacgcag ccgtcgcgtc
      661 ctggaccgtt cacgaagggg agtggtaggg tgaatcgcca gcgcatgacg ggtgggaaga
      721 gcgcgaccgt gaagcaggga gtgatcctct gggcaggcgg cgcgctcgga ggcgtcgccg
      781 tccttcctta cgccttcgat ctacagcgtg acgcgctcgc gaagagctcg gtggcgagcc
      841 tcggcttgcc gacgctggcc gccatcgcgg cgggccagac ggcggtcctc atggccatcg
      901 ccgtcgccgt cggcctccgc gcagcgcgca gcgtcggcct ccgcgccccc gtcagtgaag
      961 ccctcgcgac acgtcagccg gtgcgcgacg tcgtccaccc gttcgtgggt ccagcgctcg
     1021 gcctcggtct cctcggcgcg gtgctgatga ccatcctcga cctcttcgtc ttcctccccg
     1081 cgctgcccgc gctgcgggaa gcggggaagc cgatgatcga gcagttcgtc ccctggaagg
     1141 cggcgctcgc ctccctctac ggcggcatct ccgaggagat cctcacgcgg ctcctgctcc
     1201 tgagcggcat cgcgttcctc ctgcgggcgg cgctccgacg gcgggacgtg cctccgcagc
     1261 cggccgtgat gtggacggcc atcgtcgtct cggcggttct cttcggtctc gggcatctcc
     1321 ccgcgaccgc ggcgatcgtc ccgctcagcg gcctggtgat cgcacgcgcg gtgctgctga
     1381 acgccgccat cgccatcccc tgcggctggc tgttctggaa gcacggcctg gagtccgcca
     1441 tgctcgcgca ctggctcgcg gacatcgtga tccacatcct cgtcccggcg ctcaccgtcg
     1501 ccggcgtcct cgccgtctga cgtgcgcgac gacgatcgcc acctcacgcg cctcatcctc
     1561 gaaagcttca agaccgacga tctcgacgcg ctctgcaaag acgcggacct ctcgcccgag
     1621 cagctccagg gcctgcggga cgccttcgtc agcgccggcg ctgcgcgcat ccgcgagatc
     1681 gtccagccga gcacctggca ccaggtcggc gtcaccttcg acggcctcgg cctccagcgc
     1741 cccctcttct tcaccggccg cttcctcgag caggtccgca cctggctcga cgaccgcacc
     1801 atcgatcgct tctcgttcct cgacaaatcc cccggcttgc ggctccgctt ccgcatgctc
     1861 cgggccgatt tcccggagcg cctgtccacc ttcctccaga cctgcgccga cgaaggcgaa
     1921 ctctccggct gggtgcgccg cgcgtacgag gccgaagttc accagttcgg cggcgaggtc
     1981 ggcatggacc tcgcgcacga gttcttcacc accgaaagcc tcgccgtcct cggccaccgg
     2041 gcgctgcacc tcacggggca cgcctccctg tcctcgaccg agttctcctt gctcctcctc
     2101 cacgacctct tccagcacct cgtcgaagac cgctgggaac tctgggatct ctgggcaaac
     2161 ctcgcgctgg ccgaccgaag cctcacgctc gacgacgccg aacgcgacga cgccatcgcc
     2221 ctcgccgagc gcgcccgcga cgccatcgtc gagatcctcg acgcccgccc ctcgctcctt
     2281 caccgcctca ccgatcccga gcgcgcgctg ctccccccct accgcgacgc gacccacgcc
     2341 ctcgccgccc gcctgcgcgc cgcccgcgac gacggccagc tctcccacgg cctccgccag
     2401 atcctcccct tctggatcgt cttccactgg aaccgcatgg gcttcgacgc cgatcaccag
     2461 cgccgcctcg ccttcgtcat ggcccacctc ctcgacccca agcgcgcgga gcccccacga
     2521 tgagcccctc gtcccctcct gcaccgcgcg ctcccttctc ggcgcagtgg ttccctctcg
     2581 tgctcctccg cgtccctggc gtgccccgct cgcacctcgc cacgctcggc taccacgcca
     2641 ccctcaccca gcgccgggca gcgctggctg ctcgcgcccc cctcgaaact gcggcccggg
     2701 ccctcgccga tcgcctccac cccctcgtcc cccgggtcga cgaccgccac gcgcgccgcc
     2761 ccctcctcgc cgcccgcagg gccctcttca agctggagcc gctccccgag ggcgcctggc
     2821 gcgacaccgt ccgcgccctc gatcctgccc tccacgacga cctcgaagcg tggcgcctcc
     2881 agcacgccac gcacatcacc cacctcgacc gctgcgacgc cctcttcgac gaggacgcgg
     2941 cgaccagcga tcgtgcgctg tgggagctcc tcgcgtcgaa gcatctcgtc gccggccttg
     3001 cgctgctgaa cccctccctc tcggcgcacc tcgcacgcat cccccgctgc cctctcgccg
     3061 agctcggcgt cgacgatcgc aaggccatcg tccaggcctt ccgctacctg ctccgcgccg
     3121 cgatgaagcc cacgccgaac ggccacctcg ccgggacctt cctcgcccag atcgctccga
     3181 ccccggcgcc accgccgcag gatctcggca tgcgcaccac ggagttccag ctgagccgcc
     3241 tcgtcacgga ccgcctcgcc agcgtgctgc tggagaagcc cgcgttccgc gatcacgtca
     3301 gcgcccacgt ctccccctgc gccttcgagg aggacggcgt ggtctgggtg cttcacaccg
     3361 atccggagac tggacgcgaa cgctaccagg aggtccccga ggccagcgcg ctcctccctc
     3421 acctcgacca ggcctcctgg ggatgcccct ccccctgcgc ccactggggc gagaagctca
     3481 cacgggccac acgcgaccgc ctcatcgaga cgggcttcct ccagctctcc tggaccctca
     3541 ccgaggagac gacggcagac gacctccacg ccatcgcgca ggcgctgcac ccgtcgaccg
     3601 aagaagcccc tgaacttcga ccgtggctgg cgttcagcca ggcgatccag cagcccctga
     3661 gcgacctcca gaacgccgag accgacgagc agcgccacgc tgccctcgga acgctccaca
     3721 gcctcctcgc ccctgacccc gagcagagca cggagggaaa gaccccgctg ctcgggttcg
     3781 acgacgcagc cggcgacgca cgcctccacg tgcccgagca cgacctcgcg cccttcctcg
     3841 ccgaggtggc cctctacggc gccggctacc tcctccccgc cctcttgccc gaagagcagg
     3901 cgctgctcgc cctgcaccac cagctctacc ccgacgcgcc cagcgccccc ttgctccact
     3961 tccaccgcga ctacctgcgc ttctgcgaag cgaagcgcct cggccgcaac cacttcgcca
     4021 acctccgctc gctcgggaag cacctcgacc tccccgccac cgacgatcca gccgcccctt
     4081 tccaccaggg cctgctcgac gccatcaccc gcgcagagcg cggcgaggcc cactaccgcc
     4141 ccgatctctc cgcgctctcc cgctgggaca ccgccacgcg cacccgcgaa agcctccgct
     4201 tcgcccccgc gccgcctggt cccgcgggcc cccgcttcca cctcaccctc tggggcggcg
     4261 accggatgtc cctcttcccc cgctatctcc gccgcttccc gagcaccgcg ctgaccgaac
     4321 ccttccgcgc atggatggcc cagtggcccg ccgtggtcga catgtacggc gccttcaaca
     4381 agaaccccga cctgcgcccg ctcaccaccg cgcgcgcact ccacatcccc ggctgccccg
     4441 cgcccgtcgc ctcccccagc gccgccttca tcgagccccg cgccctcgac gtcacgcgcg
     4501 ccaccggccg gctcaccctc gtcgaacgcg ccaccggccg ccccgtcgat cccgtcttcc
     4561 tcggcgtctc cggcccccac acgcgcccgg gcttcgccca gttcctcgat cacctctcgg
     4621 gccaccgcac cagcttgctg gaactcctct tccgcgcctt gaaccgcatc gtcggcgagc
     4681 gcatccagcg cgcttccgcc caggtagagc gcctccccgc catcgtcctc ggcgaccacg
     4741 tcctcctcgc gtccgaactc ttcctcgtcc ccgtcgcctc ccttcccctc ccgcgcggcc
     4801 ccgtcgatcg cgccgccttc ttccgcttcc acgactggct cgccgaccac ggcctccccc
     4861 tccgggcgca ggtccgcgtg aaccagcgcg acccgctctg gctcgacctc gcgcatccgg
     4921 ccggcatcca gaacctcgcg aggctcgtcc acggccacac cgtctgcctc gtctcgcccc
     4981 ccctcctcga cgacgacgcc ctatggctcc gcggactcga cggcagctac gaggtcgagc
     5041 tcggcgcgga gttcatcgct ggaacggcga tctgaacccc cggcctcgac gtcgagccgc
     5101 cgcatcacgt cgaccagccc gaaccgcgcc gcctcgccct cgtccgtgca gtccacggaa
     5161 agccccagcc accgatcgtc cacgtggatc gcgatccacc gctcgaccaa ccctgccagg
     5221 aacgcgtcca gctcctcctc gcgctcgggc gaagcgatca tctcggcccc gagcgcctgg
     5281 gccacgtgca ccaggtacag atccgtgaac gagaacgaca ggagcgctgc cgcctcgctc
     5341 gccgaagccc acgcctccac gatcgccgcg cgcccatgcg ctcgccggag atgatcgtgg
     5401 atgcggtgcc ccacccccga cagcagaaac gcttgcggtt ccgcccttcg cgtatcgacg
     5461 agcagcgtcg tcctctcccc cttgaactga tagaaccgcg cgccggcccg gtgtgccgtg
     5521 atccagtgct cgatcgcgcg caagagcgcc ttctcgtacg gcggcgaccc ttgcggcaga
     5581 tcgaaatgga agtggtacga gaggttgaac cgctcctcgt cgtcgagccc ccggtacgac
     5641 agctcgaacc ccgcgagcgg ccggatgttg cggaagccga gcgcctcccg ctgcgtgaag
     5701 tacgggctgt agcgatccat cagcaccggg ttcggcccct tgggcggctc cagatggacc
     5761 aggcgctcga tcagctcgat cacgcgcagg tagccctcga ccggctcgtg cgcgaaacca
     5821 tagaggtaga gccagagcgg cttgaccccg tacgtgctgc accacttcag cacctcgagg
     5881 ttgtggtacg ccttgacccc cttcttcatc agcttgagca ctgccgagtc caggctctcg
     5941 acccctggct ggatgagccg cacgccagcg cgcgcgaact gatggacgtc ctcctcttcg
     6001 aggttcgact tggtctcgta gaagagacgg agcccctcgc cctccagccg cggcaggaac
     6061 gtgcgcaggt agcggaggtc gatgatgttg tcgaccacgt agatgtaatc gaccccgtgc
     6121 cggtcgcgca tcgcgagcgt ctcttccagt gcgcgctcgg ggctcttgct gcggaagcgc
     6181 atcgtcgccg agttcagccc gcagaacacg cagtgctgga tcgcccccca ccagcagcca
     6241 cgtgacgtct ccagcgggac cgcgatctca cgacgctcgc gcaggtgcgc caggatcggc
     6301 gccggcatct gctcgaagta atcgctgaag tcggcgaagg gcagcgagtc catcgcgtcg
     6361 agcggctcca ccgccgcccc tcgcagcacg tcaccgcctt tcctgaagac gatcccgggg
     6421 atgtcgtccg tggcccgccc cgcgcgcaga cgctcgatga accgaggcag cgccgtgtcg
     6481 gcctcaccct ggatgacggt gtccacgtac gggaacgacc gcaggagctg cacacccatg
     6541 tctccctcgc agttcgcccc accgaagacg atgtgcacct cggggtgccg cgcccggatc
     6601 gcccgcgcga gcgtcaagca cgcgacgttc tgcgagaacg tcgacgagaa cccgatcacg
     6661 tcgtacgccc cccagtcacg cgccccgagg caccgctcca gataccccgc tgccccgtcc
     6721 aggtagccgc ggatgcgctc cacggatcga gcgaaccgct cgcgggagaa attggggttc
     6781 gggatgtcgg cgatccgctc gatctggtgg cggacccgct cgctccgatc cccccagagc
     6841 gtgtcggcga agaagagatc gcccaggttg ttgaagctcg cgaggatgtt gtagtcgagc
     6901 agcgcctcct cgacgggcag ccccttggtg aagtggcgaa agaaatccgg cgcgccgtaa
     6961 tagagatccg tggcaatgcc cgcttgcagg agcgtggcct tgagcaagct ggcccccatc
     7021 gcaggcatcc agctcgacgt gaacggcatc acgaccaggc aggcccgctt cccaccgtcc
     7081 ggcaccgcgc gcacgcgcgc cttgtccgac ccgaggcccg atatcctgat caacatgaac
     7141 gccacctctc cagcaccgtc cacgcgggca ccaccgcgcg gcagggagtc gaccgggggc
     7201 cggccttcac aggagccagc cccacggcga cggttcaggg ggggaactca gaccacgacg
     7261 acgagcacca cggccgccat gacggcgacc gtcgcggtct caccggggag ctgctgctcc
     7321 gcatcccgca tgagcgccgc gggcccagcg ccggcccgct tcgcgcccca cagctcgtcc
     7381 ttgaagacgt ccgagagcac cttctgcgag tcggtccggg tcgtggcctt gaagtccacc
     7441 gcgatgccgc gcttggacag ccgatccttc acctcgctga cccggttctc gatcttctcc
     7501 agcgggatgt tgttggggag ctgcgtgcca gcaggcaccg ggatcccgcg cagcttcagg
     7561 tactcggcgg ggttggcggc gagcgcctga cgcgccgtgg gatcgttcaa gatgctctgc
     7621 tgaaactcca gaatcttgtc catgacagtc tcctcgtgct gacgggcgca ttcgcgcccg
     7681 tcgatccttc acgctcttca ctcgtgaaca ttgcgcgcgg ttctccactc tcctttccac
     7741 cccgtcagac gcccaggcgc atccattccg ccacgacgtc gcgacgatcc tcggcgactg
     7801 acagggagag gtatcgccca tcctcggcat agacgaggcc acgcccgacg agctgcctca
     7861 gtgcgccatc cggatcagac gagaattcag cacggctcca cgcgatgatc tcctcctcca
     7921 cgtccggcgc cgtgggcagc gcgggcgcga ggccgaagag gagatccagg agcgcatcac
     7981 tcgcatcacg gtcattctcg gcgtcgagag aaggcccggt ttcctgagcc gcgctggcat
     8041 cgtcaccatc gccgtcgaga ggcgtcttct tcgatgcctc cggcgcctcc accagcaagt
     8101 gcttcaaggc cttcggcgca tccagcagct cgatcaacga cgccgcgtga tccttcagcc
     8161 gataaaggcg ccgtggaaac ccgggacgtc gatcgtcgat gacgatgtcc tgccccgagc
     8221 gccgccaggt gagctgacac tcctcctcgc ggtaatgctc gtgccaccgc cgcacctcgt
     8281 gccgcagcgg ctccaggtat ggccgcggaa cctcggcccc ctcgtcgtcg cggtcgaaga
     8341 agtacgccat cctccgcagc acctcctcgg ggaagggata aagctgcgcg tacttgtgac
     8401 tcggccgcag cttgatcccg tagcgctccg gcgcctgatg gtacgggctg aagcggtggt
     8461 actcgatctc cggcaccgag ttcggcggct tcaggtgaaa gagcttcggc agctccgtcg
     8521 ccgtccgctc gtaatccgcc ggatcttcgc caggaaagcc cgccaggatg ttgtagaccg
     8581 gcaggacacc gaactcccgc gcgtacttca ggaacgcgat gttctggatg cccgtcgtcc
     8641 ccttgctcat caacgcgagc acattcgaat tgaagctctc gatgccgggc tgcaccgcgt
     8701 tgatcccggc gtccgcgagc cgctgcacct ggctccgtga gacgttcgcc ttgatctcgt
     8761 agaagaagtt gacgccgagc tgccgggcct tcgcccactc ggcgaactct ccgtagtact
     8821 tcatcgacag gatgttgtcg gtcatgaaga ggaagcgcgt gccatagcga gcgacaatcg
     8881 cctcgatctc cgcgcagaag cgatcccggc tcttctgccg gtacaccatg cctccaccgt
     8941 tcagcccgca gaacgtgcag tgctgcttcg ctccccacca gcacccgcgc gacgactcga
     9001 ggggcaagca cagcgcctcg aactcaccga tcccgagccg acctcgctgc tccacgaaat
     9061 cgtcgaagtc gggaatcggc agcccgtcga gatcgaagag cggcggcgcc ccctgcaccg
     9121 cgaggagcga gcgcttccca cgccgcgcat agatgccgtc gtgctccggc accgagagcc
     9181 cctgcgagag ccgctcgacg taatcggcga acgaggaatc ggactctccc gagaacacca
     9241 cgtcgacgaa cgggaactgc tccagcagcg ccttgcccat ctcgccttcg cagttcgccc
     9301 cgccgagcac gacctgcttc tccggccacc gcgccttgag gcgccgcgcc agcgccagcg
     9361 ccgccacgtt ctggaagaac gtggagctga tcccgatcac atcgaacggc gacagccggt
     9421 ccaccatctc ctccacgaga tccgacgcgc gctcgcgcag gtggaggatg tgctcccgcc
     9481 gcagataccg gatctcccgc cccgcgaagt gctcgtcgag cagccgccgc gcctcttctt
     9541 cgcgcatcgc ttcccgctcg ccgaagagca cccgcgtgaa cacccactcg ttgaacggca
     9601 gcatcggacg gctgttcagc agccggtacg cgcggagctt ctcttccaga tgctcgccgg
     9661 gcatcgcggt gacgacgtcg aggttccagt ggaacgtccg acacgcgaat ccacgctgct
     9721 ggatgcccgc cgagagcagc ccgagtccca ggctcggcag ccccgctggc ccgtacggcg
     9781 gatagaccag cgccaccttc agcgccgctt tctgctcaac catggaggat ctcgctcccg
     9841 agcagctggc tcagcacgtt tcggttccac tcctccgtcg ccacctcctg gagcagcgca
     9901 tcgtccacct tcgacagcgc cgacttgcag atgtggcaga ccgagtcgca gttcttcggc
     9961 agctccaccc cccgcgcgac gagcgcatcg tgcagctcct tgggtgaaaa cgtcgcgatg
    10021 aactggagca gcgcattccg ctccatccgg ccttgaagct ccgcgaggga cgtctcgcgc
    10081 aggttgccag ccacgagcgg ccgcgggacc ttccccgagc agcaggcgta cagcgtaccg
    10141 tcggggtacg cgatcggcgc catggtcacc tccgtgcagc gcgctggtgc gacctcggcg
    10201 acgggcaccg ttcgcgtatc ggcgagcggc agcgacttcg cccgcccgat ccgtgacgca
    10261 taggtccagc gcaccgtcac accgttcgca gcgccgtcga ggcgccgccg cagcatgtcg
    10321 ttcgcgttgc acgactcgaa gcgcagcgcc tcgagatcga ggccgtacgc cgcgtagaac
    10381 gccggatccg tcggcgactc gtccgccttg agcacgcggt acatccggac gagaagctcc
    10441 ggaaagctgc gcgccgccgc gatggcgtgc cccacctgcc ccggatcgag gaacttccag
    10501 tgccagacgt cgaccgacac atccagctcc cgcagccctg acgccacgaa cggctccagg
    10561 aacgccttcc ctgcctccac cgtcggcgcc cagaagccat tcgtcaccac gccgacctcg
    10621 agccccagcg accccgcgag ccgggtcagc tccaggatct cctccgggaa cagcagcgac
    10681 tccccccccg tgaacttgac cgccccgatc cccagcgccg ccgcttgctg gatcagatcc
    10741 ctcgccgcag ccggctcgaa cttggtggtc ctcttcggcc cggagctgac gcagcaatgc
    10801 gcacactcga tgttgcagcg atccgtgtaa tggaggacga tcgtctcgat cacgggctcg
    10861 cctcctcacc ctggagaatg ggcaacctgc ggatctcctc cgcatcgcga cccccgctcg
    10921 gcgcacggcg tgcagcgacc ggaagcccga acttctccgc ctcctgcgcg ctcgtgcagt
    10981 cgaccgccag cgccaggtag cgatcatcca tgggcaggac gatccaccgc tccaccagcg
    11041 cctccagcca gccatcgaga tccgcctcgg tctccggaga agggatcgtc tcggcggcga
    11101 atgcccccgc aatcgccacc aggtagagat cgtccagcga gaacgccagc gccgcgtccg
    11161 ccgagggccg cttcctccag cgctcggtca ggttctcccg cgtgcgcgcg cggcgcatcc
    11221 cgtcatggag ccagtgacca tccccggaga gcaggtacgc gcggcgctcg tcgcgccggg
    11281 tgtccacgag cagcgtcgtc ctcaccccct ggaactgata gaagcgcgcg ccgtcgacgt
    11341 accggttctg ccacccgcgc acctcgatcc agaggcgctc ctgatacggc agcccattgc
    11401 cctgcggcag ctccgccgcg aagtggtacg agatgttgaa gcgcccctcc tccgagaggc
    11461 cgcggtaata gaggttcgca cgagggagcg ggcggacgtt cttgtagccg tactcctcgc
    11521 gtcgcgtgaa gatcgggctg aaccggtcca tgagcaccgg gttcgggctg cgcggcggcg
    11581 gcaggtggac gaggcgcggc aagagcgcca catcccggaa gtacggcgcg tgcggctcgt
    11641 tcgggaagcc atagaggtag aaccagaccg gcgtgacgcc gcccatcgcg caccacttga
    11701 gcagctcgac gttgcgatac cccttcaccc ccttcttcat cagctccagg atctcggacg
    11761 acagcccctc gatgcccggc tggatccggc gaatgccgct gcgcgcgaac tggtagacct
    11821 cttcctcgct gaggttcgac ttcgtctcgt agaagatgtt cagcccatcc tcttcgagct
    11881 tcgggaggac ttccttgaag tatcgcttgc tgatgatgtt gtcgaccgca tagaactggg
    11941 tcacccggtg gcgctcaccg agccaccgga tctcctccag cgcgcgctcc gggctcttgc
    12001 tgcggaaccc catcgcgctg gagttcagcc cgcagaagac gcagtgctgg atcgcgcccc
    12061 accagcaccc acgcgacgtc tcgaaaggca acgacagcct cccggacgca cgcaggtgct
    12121 gcacgaccgg cgggagctgc tcgaagtaat cgtcgaagtc cggcatcggg agcgcatcca
    12181 tcgcctggag tgggacggac tcgggccccg tgcgcacctc gccgccgtcg cggaagacga
    12241 tccctggaat gtccgcggtc gagagcccct gccgctgcgc ctcgatgaac ctggggaacg
    12301 agaaatcggc ctcgccctgg atgacgacat cgacctgcgg aaacgagcgc agcatctccg
    12361 cgcccatgtc cccctcgcag ttcgcgcccc cgaacacgat gcacagctcg gggtgccgct
    12421 ccttcagaag ccgcgccagc gccagcgacc cgacgttctg cgagaacgtc gaagagaacc
    12481 cgacgatgtc gtactgacgc cagtcgcgcg cgcgataaca ccgctcgacg tattcccctg
    12541 ccccctcgac gtaccggagg atgcgctcca ccccttgcgc gatgtcctcc gcagcgatgc
    12601 tcgggttgtc gacatcgcgc aggctcatca cctccttgcg gacgtcgtcg aggcacccac
    12661 cccacagcgc gttcgcgaag aagacgttgc cgagatcata gctgacggca atcagctcgt
    12721 aatcgaagat ggcgtcgtaa tgatcgatgc cgtccgtgaa gacgcggaag aaatccagcg
    12781 ccgcatagta gatgtcggac gcgatccccg cctgagcgag cgtggccttc agcgtgctca
    12841 ccccgagccc cggcatgacc accggcgtga acggcatgac caccagacag acccgcttct
    12901 ccctcggtgc ttcggccccc atcactcgac ctccgcggca ggcgtcgcgc tggtggtggc
    12961 ctccgggagc agccacgcga atgccttctg aaatgacgcg cgctcggcga tctcatccat
    13021 ctcctgcgcg ctcaccccgt cgcaagcccg gacgcacacc tcgcagatgg aggtatgacc
    13081 aggtcgccgc ttccgatcct gccggctccg ccccacggcc aggtacagct ccttggggcc
    13141 gtggtcgttg atgaacttga agtgagcgcg ctcggtcatc cgctcgacga gcgtggccag
    13201 cgactccttg tggaggttgc ccacggtgaa ccctgcgatc ttgccgcctg cgcagcagca
    13261 cgcctggagg tcaccatccg ggtagatgac cggcttgttg acgatctcgt ggcacccctc
    13321 cgacgggaag accgacatgg ggaagtagcg cagctcctcg gggtactccg cagcgcggcc
    13381 gaggccgatg agccctgccg cattgaccag gatcttgtgc ttccagttct gcaggtcctc
    13441 gcgcgcgtcg aggagcttgc gcagatcgac gaggtcctct ctcggcagcc cgtacaggtc
    13501 gctcagggcg tcgagcggat cgccctcccc cgggtggacg tagccgagga tgcgaagaaa
    13561 atcgaggcgg cgcgtgcatt cgagcgcatt acgaaggatc ttcggatcct ggaactccag
    13621 gtgatacttg tcggcgctga aattgagttc cgtgagacct gcctccttca tgcgcgacag
    13681 gaattcgagg ccgcggtcga agttcttggc ccagaaaccg ttggtgacga cgcgcgtctt
    13741 caggcctgcg gccttgcaga tctcgaacat ctcggcgtgc tccttctgga agaggaaggg
    13801 ctcgccgcca gtgaaattca ctttccggat gaccgggatc tcggtcgcct cgcgaatgaa
    13861 tcgcttggcg tcctcgaagc gcatcgtctc cttgttctcg ggactcgaca gaatgccgca
    13921 gtgcttgcac gcgatgttgc acgtgcgcga gtacatcaat ccgagctcga tctttcgatc
    13981 cgtattcatg gaaggtcctc caccgcggca gcgacggcca cacgctcgga atcggctcac
    14041 cccatccatc agcacagcgc gtcaaggtga gcgcgcggct gtacccgatc gccatcaagg
    14101 atacggtcca ctaaccacgg ttcaatcgaa tttcgtccga gcggcatacc agtgccgcgc
    14161 cgttcaccgc tgaatgatgg tcatttcgcg tcgtattgcg ctgatccgac cgatgcgacg
    14221 cgcattctcc gggttcatcc ccggatgggg tgttcacgcg cgctggcgga ggtgcacagg
    14281 gatgcgcgcg ttcgatgaag gggtgaatgc attgaccgtg caggccatcg cacgcccggg
    14341 caaggcgatg gccatggcgg ggacatggac gatctgggag atcggacgga cgaccctggt
    14401 ggggccgctg cgcggcgggg gcggggcgcg gcagtgtcgc ttcacggcgg ggcaccaggt
    14461 ggggaccatg acggaggctg cgccagtcga ggtccggtcc accagggagg acgccatcgg
    14521 tccgcgagag ggcggtcgcg cgctcgtcct gctcgtcctg cacgaggcgg ccgtgcagcg
    14581 ggaccgggta ccacgacggc acccgatccc ggcgcatgga tcatcccctc gacctccccg
    14641 gagggcggct cccttgctgg cgcaccgcct ccgaggcgtc gctctcggcg accttcgctc
    14701 agcccgcgac gctgtcgggc gctggctcga aggaccgcgc gctcgtcgtc gggctcgtcg
    14761 tcgggctcgt ggcgacgggg acaccgcagc tcccgggcgg ctgcacctcg tccacctcgt
    14821 ccacctcgcc atcctgcttg cgccgcttcg gccgcagccg ccgcagcgct tgccggaacg
    14881 aggcgccctc gaagcgcacc cgcaccttcg gctcgtggaa gcaagcgttc acgccggccg
    14941 cgcgggcctc gcgcccgagc atcacggcgt aggtcaggat ctcgttgcgc agcaggatcg
    15001 cctcatcctg atgccggatc cccaggatgc cgagcagatc gcgcgactcc gcggtccgca
    15061 gcagctcttc cccttcgacg aggaacgcct cggtcacgcc gacggtgacg aggcgagctt
    15121 gccgagcgcg cgcctcgttc acgagcacgc gcaggtcggc gatctcctcg gcgacggtgc
    15181 gcgagcggtt cacatcggcg aacagcgccg cgaccttcgg ctcgaagacg aacgcctgcg
    15241 cgccgtaggc cttgagccga gcacggtagg gccggctcag cgcgacgaga tcctcgacgt
    15301 tcagcgtgcg gtaggcgccg gtgcgggccc cctcgccgaa ccagaggtgc ccggtgtcga
    15361 gcaactggat ggccgcacag aacgcttctc gacgaccctg gccatagccg acggtcgcca
    15421 gggcagccga ctgctcgatg acggtgaggt acagatcgcg cagctcgatc aggatgtcgt
    15481 cgatggcctg agcaggcgcc atcacctcct ggaccacctg gtcgatctcg ggacgtgccg
    15541 cggcgagcag cgcctcgaac tgggccgggg tgtcgagcgc ccgggtctga acgaggacgg
    15601 cctgctgtgc gggagataac gtaattgcca tggttcccct cctccttttt ggttggtcct
    15661 aaacgggagt ttccggttag gggggatttt tcaggtataa atccgcaccg agcggagtca
    15721 accaaccgac ctgcattttt ttgacatttc cagacggcgc cctggaggct ggaggcggcc
    15781 cggcgcctcg ggcccggggt gccaggcggg agcggccacg caggccgcga tgctcacgca
    15841 ctgggcggca gacatcgtgc tccacatcct cgtgccgtcg ctcgtcctgg cggggatttt
    15901 cggcatagcg cgccgcagga tcatcgtcgt cgcggccgac gtcgccccgg gaagccgcgc
    15961 gcggccgaag gcctggagcg ggccacgacc ccgagccggc gctggcacgc gcggcatgcc
    16021 tggcccctcc agcacgagcg gcatgcctcg ctctcccacc cagcctgcat gccgtggtgc
    16081 cgtgccagca gctcggggcg ccgtaccagc agcccggggg gccatgccag cgccccgggg
    16141 cggtgtgtca acaagtcgcg ggaccgttgc cagcagggcg aggtcgcgtt tcagcgcgcc
    16201 gggggacgtc gccagcagcg cggggtcggc ctccagcatg tccaggtgct cgcccgcacg
    16261 tgctggcatg ggcccacggg ctgctggcac gacgccacgg gctgctggca cggcgccacg
    16321 ggctgctggc atggcgccac gggttgctga atcattctgc aagcgagtgg cacgtggcaa
    16381 cgacgtgcgg gctcgatgac gcgcggtaca tggtttgaat caattgaatc aaagtcgcac
    16441 gtgacctgcc ccggatctac ccaacgggag atcgggcaga attcctccga gaagctcacc
    16501 cggccctcag tcgcacacgc gggacgtcag ggcactcgct gtcgctcgaa gcgaaagccg
    16561 ctcaccggcc atccaacatc gatctggcct gcactatcag tagccccctc ctagcccagg
    16621 ccaatccttg catccggtcc actgtccatt gatgcatctc ttccagcccg agcaccagtt
    16681 gaccatacaa tccacgctgg gggtgacctc ctgcatgcag gtctgcttgt caggatcgca
    16741 tgcaccacca agggccaggt catctacgca cttccagcaa cagggtctgg catctcctac
    16801 ctcgcaaaca ggtggagggc agccctcgtc caccacgcca tcgcagtcgt tgtccaggcc
    16861 atcgccacac acctcggcca tgttcggcct tcgctggctc ctggtgtcgt cacagtcgcc
    16921 cgcgttgctc acataccctg gaggtgcagc gcacgcctga atggactgcg ccgggttccc
    16981 gaagccatcg ccatcagcat cccggtagta cgtattgccc gctgcccctt cgtcgatgga
    17041 tccatcacag tcgttgtcct tgccgtcgca gacctcgggc gacggcaagt acaagggggc
    17101 gcactcgatc gcgccgctgg tgcaataggt cactccctcg gcgcagacgc cgagcttccc
    17161 ggggaccgag cagccgaatg tcccgccggg gttgtcgtcg tcgacgacgc cattgcagtc
    17221 gttgtcgagg ccatcacaga cttcggcgga gggctggttg accgcgtgac acgccagcat
    17281 gccctggatg cagctctgcg tgcccacccc gcagacgccc agcgctccgg tcgcgcaggt
    17341 gccaccgctc tcggggttgc cttcgtcgat ctcaccgtcg cagtcgtcgt cgaggccgtt
    17401 gcacagctcg tcggcgtcgg gcgagatcgc cggatcgtag tcgtcgcagt cgtccgcgtt
    17461 gtccacgtac ccgtagggcg ccgtgcatgc attgaagtac tgccatgcgt cgccatggcc
    17521 atcctcgtcg aaatcgtaga agaacgtgcg cagcacggag gtttgctgtg cgcgcgtctg
    17581 cggcgtctgc tccgcgatcc ccagcccgag ctggccctgg gtgttctggc cccaggccca
    17641 caccgggcag ccgctcgaca aggccacccc atggttggca cctgccgaga ggccgatgac
    17701 ctgcgtgagg tgaggtgtcg agacggggct cgggcggttc gccgtggtct cgtcgccgag
    17761 ctggccgaag ttgttctggc cgaaggagag cacctgaccg ctcggcccgg agagaacgag
    17821 ggagaaggcg ttccccgcgg cgatgagcga tgcgtcgccg aggaagggaa tctgctgggg
    17881 cgtggagacc gggctggtcg tgtgcccgag ccccagctgg cc
//
