LOCUS       NZ_CP012159            21976 bp    DNA     circular CON 02-MAY-2024
DEFINITION  Chondromyces crocatus strain Cm c5 chromosome, complete genome.
ACCESSION   NZ_CP012159
VERSION     NZ_CP012159.1
KEYWORDS    RefSeq.
SOURCE      Chondromyces crocatus
  ORGANISM  Chondromyces crocatus
            Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae;
            Chondromyces.
REFERENCE   1  (bases 1 to 11388132)
  AUTHORS   Zaburannyi,N., Bunk,B., Maier,J., Overmann,J. and Mueller,R.
  TITLE     Genome analysis of myxobacterium Chondromyces crocatus Cm c5 reveals
            a high potential for natural compound synthesis and the genetic
            basis for the loss of fruiting body formation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11388132)
  AUTHORS   Zaburannyi,N., Bunk,B., Maier,J., Overmann,J. and Mueller,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2015) Department of Microbial Natural Products
            (MINS), Helmholtz Institute for Pharmaceutical Research Saarland
            (HIPS), Campus E 8.1, Saarbruecken, Saarland 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Newbler v. 2.6, HGAP SMRTPortal v. 2.2.0
            Assembly Name                     :: Cm_c5_Newbler_HGAP3_v13
            Genome Coverage                   :: 366x
            Sequencing Technology             :: Illumina, PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001189295.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 07:18:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,280
            CDSs (total)                      :: 8,172
            Genes (coding)                    :: 8,124
            CDSs (with protein)               :: 8,124
            Genes (RNA)                       :: 108
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 96
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 4 of 48
            Pseudo Genes (incomplete)         :: 44 of 48
            Pseudo Genes (internal stop)      :: 3 of 48
            Pseudo Genes (multiple problems)  :: 2 of 48
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:43:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3868938
            Orig. end                         :: 3890914
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012159.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21976
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="thioamitides"
                     /region_number="13"
                     /rules="((YcaO or TIGR03604) and TfuA)"
                     /tool="antismash"
     cand_cluster    1..21976
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and TfuA)"
                     /kind="single"
                     /product="thioamitides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21976
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11976](-)"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11976)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
     gene            616..7242
                     /locus_tag="CMC5_RS14495"
                     /old_locus_tag="CMC5_029410"
     CDS             616..7242
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015497.4"
                     /locus_tag="CMC5_RS14495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_029410"
                     /product="FG-GAP-like repeat-containing protein"
                     /protein_id="WP_082362493.1"
                     /transl_table=11
                     /translation="MPTQASRPQHALPSVSGCSFPSQRRRPLPPALLLLIAVLLVGACS
                     DAGSPLVWSSASQTLWDASPIPPIPPLLCLGPDEGPSPFPPDLAQGTTSAAGTLPGSFS
                     VTSTGEATYTIPVPTLPGRAGIEPSLAITYDSAQGEGLLGIGFHLQGLSSVERCPRNVA
                     QDGHIAPVRDAEDDALCLDGQRLVPVDPQPGRVAREYRTFPDSFTRVEADFAESEGWPA
                     ERGPKRLRAHSKAGLIYEYGGESSGRVLAREEVVRSWLLTRLSDRDGNTMEVVYRNDLH
                     AKGYTVEHAPQQITYTGHPSVPASRTVEFAYGPLESADVRVLYARGMELRRSLSLRSIQ
                     MFGPGHVLARELRFGYGHGPATGRLRLEAVRECGGDGTCKPPTRFTWHTAGAAGYRQQQ
                     TPVEVPLSERGTLMTMDVSGDGLDDLVTSDMVVEAGTEQPITRWSVTLNRSQELTPAFF
                     EAAVTGQEQPHFIDAEPPYQPELGTPLDYDHDGRMDLFLHDVHGQALTWEVLLSDGDGT
                     FTRRDTGVPRPFTMGMTPAGLRSPDASTHLVDVDGDGMVDLLQCYKSAHEQLWYLHRWT
                     AAAGGFEPHGDRVHALTPYPCHAELHAIDVDTDGRVDLVMQELVLVGSQVRAGSQYVAF
                     AYELSDGSWTRALMNLRLTPPGDRVFFLDVNGDGLPDAVQSNRDDEQLYTSMNTGAGFA
                     EPVPSLATPMLGAARFVRFASVLDHNADGRQDLLLAMSDGGSESLPAWKVLQATGEIGP
                     GTFEIVHPGLPMGVVLQQDELPTPDHPLTPRVTDVNGDGAQDLLYAFNNQVHVFENVLG
                     QEDLLAAVTDGMNAHDPEDAEYLPNVQIRYDHLIDRARTTAGFEDTTGIPSPEQRTYRT
                     LEHSDEDQCRYPVRCVVGHRRVVSGYVLNNGADRPRTFQVAYRNGRHHRLGRGFLGFGT
                     RIVRDLDTGAGTAEFYDNVTFDGAFQAFPFRGQVQRSWRWSPSLPLDAHSAEPVSVELL
                     TTRSYPVVIPTQAGTYFTLSLLEGKSRHQGTFLPGGGKGLEESVRDLEGDLSTRMSDTL
                     RTVSDFDLYGNILAEQTQTDGVDLELTVTRSFDNDPLSWRLGELTRETTCSKAAGETQC
                     RVMHRSYDGRGHVRMERVGGEPFDPEMQLDVWFSRDALGNIHNTRSRDGTGQVRASCIS
                     YDALGLMPHAHRNLEGHQSYTRYDPALGVLQASVDPNGLVSRWAYDGFGRVTLESLPGR
                     MPTAIRRTWTKDGGAAGNAWNLKIRTSSAGGQDETVQFDGLGREVRWWWQALDVGEEQA
                     PRMMQEVGFDARGEHLAWRSLPIAAPAPPGSMQVRETWQYDGMGRVLRHVTPWGAATTH
                     EYIGRDEVITAPGQAVTRIASDALGRPTAVGDPEGGVTRYTYGPFGGLRTVTTPAGATT
                     LTERDAFGRVRRQVSPDRGVSTAHYDGYGQKVSSLDAAGREVTTSYDTLGRITRQVDED
                     GVTEFRWDDAPHGVGQLALVVSPDGHRLRYGFDHLGRPATTTLELGGESFTSRLSYDLS
                     GRLKRIEHPSAPGIGSFAVEREYDPYGRLRALKDAGSGAEFWRATAIDAGNRITGERFG
                     GGTASTLRTFDAARERVSRIATQAAGVPVQEFAYLWNDRRKLVERSDGIHANVERFRYD
                     LLDRLTCAQFGLINAALCPRPFIYGPDGNLLQKPGVGAYEYDPAQPHAVVRAGSAFYGY
                     DAVGNQTSRPGATIAYTAFDLPKQISLTSGDTVDIEYDGLQQRVRKTTATQEIVSFGEL
                     YERVTDVVTGNVEHRYHVHNDERVVSLVRRSTAQGTRTLHVHADHLGSIDVLTDGVTGS
                     VAEQRSYDAFGAPRHPDWGSGQTASPHELSSLGFTGHEADLDLGLVNMKGRIYDPKLGR
                     FLTPDPLVPRPLFGQSWNSYSYVLNSPLSLVDPSGFQEQPPATEDGCSQGCTIWVFGPP
                     REPKPPAPPKVVEGNLEEAAGAGSTQAPIDVGTSGVRGGWSPQLPATLQALGRGDAIAR
                     RIMDGVRIGMARMLLESAKLGVLGGTSRVYVAYTTITAAWNGYKESGLPGALDAVNPAS
                     QMVEAGVEAYDAAAAEDWESAGASLFKAGSIGMSILATAVGVGGAISATIGSTARTVGR
                     ASVGPTRGGGPGARPSQPFSKAGKDEVWKQNATKHSGVNKCENCGSDVIKPQQHTKGVT
                     PPTNEGHVDHVTARVKGGSGTPDNGQVLCRGCNLEKGAQ"
     gene            complement(8326..9162)
                     /locus_tag="CMC5_RS14505"
                     /old_locus_tag="CMC5_029430"
     CDS             complement(8326..9162)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS14505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_029430"
                     /product="hypothetical protein"
                     /protein_id="WP_050430981.1"
                     /transl_table=11
                     /translation="MLNTTRLEVDRQINVGNALGPILAAPRATPLQGATRTRGDAVIAS
                     TLALLNVRDVPPRAADQATDTVVTAFHRMLEAREEMLLDTLVPLGPAQREVLGQVRLLR
                     TRLFPKGTSFIRLPMEMELKHLTDLRQRLGEPEVDAAVTALGLEAEVLHLVTHVERYGR
                     SLGQDAGGAGRATELASVAWHEAFVRFAAQVVVDYEGNTAMQRELLGPYEGQRLQQRAA
                     ARAARRARAAAQGSSTPPLGGSPAKGLERGLDGIEEEEALDEEPPSMTGGATPAAG"
     misc_feature    complement(9172..9187)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.42"
                     /tool="antismash"
     misc_feature    9180..9194
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.94"
                     /tool="antismash"
     gene            complement(10001..10753)
                     /locus_tag="CMC5_RS14510"
                     /old_locus_tag="CMC5_029450"
     CDS             complement(10001..10753)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002616595.1"
                     /locus_tag="CMC5_RS14510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_029450"
                     /product="TfuA-like protein"
                     /protein_id="WP_050430982.1"
                     /sec_met_domain="TfuA (E-value: 1.9e-46, bitscore: 155.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVIFLGPTLSVTEASGVLEATYLPPAAQGDVYRAACERPAAIG
                     IIDGYFDHVPSVSHKEILWTMKEGIHVFGAASMGALRAAELATFGMEGIGDVYESFRRG
                     HIDADDEVATAHAPAEGGYRPLSVAMVDIRATLAGAVRDGVIGVDTQKKLIGLARSSFY
                     ADRSYPSLLGSASDAGLLDSEIAALRSYLPERRVDRKRLDALELLRTMDRRVKSGITPK
                     QVRYHFQHTEAWEQIAQGARRLRATDPA"
     gene            complement(10750..11976)
                     /locus_tag="CMC5_RS14515"
                     /old_locus_tag="CMC5_029460"
     CDS             complement(10750..11976)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012239732.1"
                     /locus_tag="CMC5_RS14515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_029460"
                     /product="YcaO-like family protein"
                     /protein_id="WP_050430983.1"
                     /sec_met_domain="YcaO (E-value: 2e-71, bitscore: 240.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAIKRHLAGTHRLVTPTETVERMRRMMPITGITRIADVTGLDTI
                     GIPVVMVVRPNARSLSVSQGKGMDLDAARASGLMESLELWHAEQIDRPLKLATFNELRF
                     THRLVGVAALPALLVGQFHQNYRTLWIEGTNLLDGASTWVPHEMVHMDYTLPLPSGSGS
                     FLMSSRGLASGNAPQEALAHALCELIEHDCTTLHRSSTEAIQRSRRVDPDTVDDAGCRE
                     LLGMYERAGVEVAIWDTTSDVGVAAFMCTIVDREPNPNRLIGPMGGLGCHLSRAVALSR
                     ALTEAAQSRLTLITGSRDDVLHQAPQSASRDVEAARRMTAALAAEPRTRHFHETPDRWN
                     ESFDDDLAQLLERLRAVGIEEVVAVDLTKDLFEIPVVRVIVPGLEPLSDVPGYRPGARA
                     RRRLLENVQ"
     gene            complement(12005..12511)
                     /locus_tag="CMC5_RS14520"
     CDS             complement(12005..12511)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS14520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156338594.1"
                     /transl_table=11
                     /translation="MIQPDPTHECLEGLGLAGMLIVESVTLTRDPAGDPETAEQTETAA
                     QLPLLVRGTITATYEEEGQTYETRTDVYVCTNNRCDPKKTMIVYGPDGEYWFIDMSTKN
                     QWSFASMESGPAEVGVLAHHGTVVSWVEPPAPRGVPSYFVTCFVLNMKALSQTIPAAHS
                     GPDGD"
     misc_feature    13093..13107
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    13453..13468
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.0"
                     /tool="antismash"
     misc_feature    complement(13454..13470)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.99"
                     /tool="antismash"
     misc_feature    13455..13469
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 24.27"
                     /tool="antismash"
     misc_feature    complement(13456..13471)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    14171..14187
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            14246..15697
                     /locus_tag="CMC5_RS14530"
                     /old_locus_tag="CMC5_029480"
     CDS             14246..15697
                     /EC_number="4.3.1.17"
                     /GO_function="GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009063 - amino acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013938158.1"
                     /locus_tag="CMC5_RS14530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_029480"
                     /product="L-serine ammonia-lyase"
                     /protein_id="WP_050430986.1"
                     /transl_table=11
                     /translation="MAISVFDLFKIGIGPSSSHTVGPMRAARSFALALHEAGLLDRTAA
                     VRSELFGSLGATGRGHGSDKAVILGLLGETPDEVDVERVDDMVTEVRRGGALRLLGRRV
                     VAFREPAHLALVRRSLPHHPNGMRFTALDETGASVLSRVYYSVGGGFVVDAPEPVDEAG
                     STSSRSPTALQGARDAEDSSLPHPFHTGAQLLARCQASELSISQLMLANERVTRSDAEI
                     RAGLDRIWQVMQTCVQRGCRTEGILPGGLKVHRRAPALYRKLMDHPEAGLRDPLTALDW
                     VSLYALSVSEENAGGGRVVTAPTNGAAGIIPAVLHYYRRFVPTATDEGVQRFLLTAAAI
                     GVLYKENASISGAEVGCQGEVGSACSMAAGALCEVMGGSPAQAENAAEIAMEHNLGLTC
                     DPIGGLVQVPCIERNAMAAIKAINAARMALHGNGQHFVSLDKVIRTMRITGEDMKDKYK
                     ETARGGLAVRFVEAPADVSVGLPEC"
     misc_feature    14252..14266
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            15877..17394
                     /locus_tag="CMC5_RS14535"
                     /old_locus_tag="CMC5_029490"
     CDS             15877..17394
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /locus_tag="CMC5_RS14535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_029490"
                     /product="PAS domain-containing protein"
                     /protein_id="WP_082362494.1"
                     /transl_table=11
                     /translation="MPHSLHSLCCVAVATAGHKLSWEDCLMTTTEAAPAKSIRSVELDQ
                     TMLTWETDSGLLGHHGRRSAMFWLEPSLFQLLAPLVEELGVPLFRLTVAYHASLGARDD
                     HRISIANEGACFPEVLEGWGRSVEVCGWGKFELKWFDEEACRALVRVHHPWELAVQRAA
                     KERWGSPFLFGKLVGLFSLVSGFNCWADEMEGEDENGVPIVDFLLYRSDRTIEEELKIL
                     RREHDEEARRPLRQKMQELWESKERQRAVLASLGEVVLTVDRGGRITSFHVPRDQAAFH
                     PSPELAIGKRLEEALPPDVAAALGEAVQQVLGGEPHLPASYEIAAAGEVRGYSAKLTSI
                     HDAAGAVVGVTVLARDLTERLRIERALETQLAVIEQQQEAIRMLSTPVLQVWDGVVALP
                     IIGGVDERRVADITATLLDTVARTQARYAILDVTGVDAIDRRTADHFTRIRRAVTLLGA
                     ECLLCGMRPGVAQAMVATGVEMDQDRGPRARNFGTMQAALQAVIGRR"
     gene            17439..18188
                     /locus_tag="CMC5_RS14540"
                     /old_locus_tag="CMC5_029500"
     CDS             17439..18188
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445419.1"
                     /locus_tag="CMC5_RS14540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_029500"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_050430988.1"
                     /transl_table=11
                     /translation="MHYVEHPPAPALREVVRCLWSHEGVTGSVPFHVLPDGCLDLVWDG
                     VALKVAGPDTRPFLTTLPEGYAITGLRFHPGVAPTALGVPASALRDSRVALEDLWGVEA
                     VRLAEALGEAPSTDAKEALLASALARRVVSAPAPDRLVKALVGRFMRVVGEASAPPPSV
                     ELLADELGVSSRQLLRRCTDAVGYGPKVLLRVLRFQEFLRQARAQPALPLARLAVSCGY
                     TDQAHLAHEAMALGGKTPGALRGVVDG"
     gene            18279..19214
                     /locus_tag="CMC5_RS14545"
                     /old_locus_tag="CMC5_029510"
     CDS             18279..19214
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545413.1"
                     /locus_tag="CMC5_RS14545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_029510"
                     /product="hypothetical protein"
                     /protein_id="WP_050430989.1"
                     /transl_table=11
                     /translation="MRHLDLSALEAAERFVWLSGRVLERLRFAHLFRHGDAARVLSALR
                     PYQNPDGGFGEAIEPDFRGPVSQPLSVDFALHIVDEVGGFEDPMVGAALGYLASITCED
                     GGVPNVLPDVPRYPHAFWWAPAPGPLVGSLLPTASIAGLLHKHRVAHPWLERATSFCWE
                     AIEGLPARVAVAEGRIPRLQIAYETRAALVFLEHAPERARAAQTARALGELLLGRGGFI
                     AAGEGTAGEMSLLDVVSRPGSPARAWFSDAQVEQHLDALLAEQGKEGGWSVSWPAWTAA
                     AGLEWMPIQTVERLKTLKAYGRLTLPAAGG"
     misc_feature    19372..19385
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     gene            19474..19773
                     /locus_tag="CMC5_RS14550"
                     /old_locus_tag="CMC5_029520"
     CDS             19474..19773
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012233075.1"
                     /locus_tag="CMC5_RS14550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_029520"
                     /product="CsbD family protein"
                     /protein_id="WP_050430990.1"
                     /transl_table=11
                     /translation="MSNESKRAEGAAEELGGKIKKGIGQLIGNEQMEAEGAAKELKGEA
                     KQEAAKAAERVKGAIEEATGAIKNRVGHLIDNEQMQAEGRARELKGEARQKANE"
     gene            20160..20912
                     /locus_tag="CMC5_RS14555"
                     /old_locus_tag="CMC5_029530"
     CDS             20160..20912
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020737570.1"
                     /locus_tag="CMC5_RS14555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_029530"
                     /product="hypothetical protein"
                     /protein_id="WP_245678440.1"
                     /transl_table=11
                     /translation="MQEQTIGGWSADFMRELPEKPSAHREDAILRAARDNRLAPITWME
                     VTSKKNNRTVVLFVSADALRLGDEHASVRVTVSARTTQRIADALGCVLPTTKICDLIWE
                     QAAVKLAPCIQSPDKAMGYTSRMIQHHDRVEKARAGRPGLIENVGKHWVLTNRLASKRD
                     ASANYGWYDHRAPYLSGKHRVWQPLGLAHNLDHVDYSQVVRLVQQCCLVDGEERDLKEV
                     LVDRELSPLVSNEGPLKFTRLPGVKLDA"
ORIGIN
        1 gccggttccg gcgaacttcg tggtacttcg acgcaacgcg tacggtgatt ttgttcagcc
       61 aacgctcggg ccgagcgcgc cgcgggtcgt agctctggaa gctctggtgc gccgcgagca
      121 aaacgtcctg ccgtgcgtcg tcgcggtccg ttgaagggac accgagccga gcgagccatg
      181 ccttcacggc gcatcgtgtc ctcgggtcga agatggcggt gtaggccatt cgtctttcct
      241 gctcccaggt tccggagcgt gcgccttgga ctcgtcgcat cggggctcga gaggccattg
      301 tgacgacgag gcctgctcga tgtggaaatc gacggccgat gcatggatgc tcacgctaca
      361 ggagcgaatc gtcggcatgc aggagggcgc gcaggggcgt catgctgggc atgaggcgtt
      421 ccgcgcggtg gatgctggac ggcacccatc gaatcggtgc gtcgtgcagg gagccagtca
      481 cgcagcgatg accgagtaac tcgtgattct cggcatcgcg gcacgtgcgt cgtggcgagg
      541 tgagactcgt cggtcgatta ggatgcgagg catgtctcat cgggcttcat tggcctgcca
      601 ggagatagcg cgcccatgcc gacacaggcc tcccgccctc agcacgcctt gccctccgta
      661 tcgggttgtt ctttcccctc gcaacgacgc cgtcccctcc ctccagcgtt gctcctcctc
      721 atcgccgtgc tcctcgtcgg cgcgtgcagc gacgctggct cacccctggt ctggtccagc
      781 gcctcccaga ccctctggga tgcgtcaccg atcccgccaa tccccccgct cctgtgcctc
      841 ggtcccgacg agggtccttc cccgttccca cctgaccttg cgcagggcac cacatccgcc
      901 gcaggcaccc ttccaggctc cttctcggtc acgagcacgg gcgaggcgac gtacacgatc
      961 ccggttccca cgctgccagg ccgcgccggc atcgagcctt cgctggcgat cacctacgac
     1021 agcgcgcagg gcgaggggct cctcggcatc ggcttccacc tgcaaggcct ctcgtccgtc
     1081 gagcgatgtc cgcggaatgt ggcgcaggat ggtcacatcg cgccggtccg ggatgccgag
     1141 gacgacgcgc tgtgccttga tgggcagcgg ctcgtccccg tggacccgca gccggggcgc
     1201 gtggcgcggg agtaccgcac attcccggac agctttacgc gcgtcgaggc cgacttcgcg
     1261 gagagcgagg ggtggccagc ggagcgtggg ccgaagcggc tgcgggcgca tagcaaggcg
     1321 gggctgatct acgaatacgg tggagaatcg tcgggaaggg tgctcgcacg ggaggaggtg
     1381 gtgcggtcct ggctgctgac gcggctcagc gaccgggatg gcaacacgat ggaggtggtc
     1441 taccggaatg acctccacgc gaagggctac acggtcgagc atgcgccgca gcagatcacg
     1501 tacaccgggc atccgagcgt gccggcgtca cgcacggtgg agttcgcgta tgggccgctg
     1561 gagtcggcgg acgtgcgtgt gctctatgcc cgggggatgg agctgcgccg ctcgctgagc
     1621 ttgcgctcga tccagatgtt cgggccggga cacgtgctcg cgagggagct gcgcttcggt
     1681 tacgggcatg ggccggcgac gggtcgcttg cgactggaag ccgtccggga gtgcggggga
     1741 gatgggacgt gcaaaccgcc gacgcgcttc acctggcaca cggctggagc ggctggctac
     1801 aggcagcagc agacgcccgt ggaggtgcca ctgtcggaac gcgggacgct gatgacgatg
     1861 gacgtcagcg gcgatggcct cgacgacctg gtgacgtccg acatggtggt ggaggccggc
     1921 acggagcagc cgatcacccg ctggtcggtc acgctcaacc ggagccagga gctgacgccg
     1981 gcgttcttcg aggcggccgt cactgggcag gagcagccgc atttcatcga cgcggagccg
     2041 ccgtaccagc cggagctggg gacgccgctc gactacgacc acgatggccg gatggacctg
     2101 ttcctgcacg atgtgcacgg gcaggcgctg acgtgggagg tgctgctgtc ggatggggat
     2161 gggacgttta cgcggcggga tacgggggtg ccgcgaccgt tcacgatggg catgacgccg
     2221 gcgggactgc gcagcccgga tgcgtcaacg cacctggtgg atgtcgacgg cgatgggatg
     2281 gtggatctgc tccagtgcta caagagcgcg cacgagcagc tctggtactt gcaccgctgg
     2341 acggcggcgg caggaggctt cgagccgcac ggggatcggg tgcatgcgct gacgccgtac
     2401 ccgtgccacg ccgagctgca tgcgatcgat gtcgatacgg atgggcgggt ggacctggtg
     2461 atgcaggagc tggtcctcgt cggcagtcag gtgcgggcgg ggtcgcagta cgtggcgttc
     2521 gcgtacgagc tgtccgatgg atcgtggacg cgtgcgctga tgaacctgcg gctgacgcca
     2581 ccgggtgacc gggtgttctt tctcgacgtc aacggggatg ggctgcccga tgcggtgcag
     2641 agcaaccggg acgatgagca gctgtacacg tcgatgaaca cgggcgccgg tttcgcggag
     2701 ccagtcccga gcctggcgac gccgatgctc ggggctgcga ggttcgttcg cttcgcgtcg
     2761 gtgctcgatc acaacgccga tgggcggcaa gacctgctgc tggccatgag cgacgggggc
     2821 tcggaatcgc tgcccgcgtg gaaggtgctt caagcgacgg gggagatcgg gccggggaca
     2881 ttcgagatcg tccatcccgg gctgccgatg ggcgtggtgc tccagcagga tgagctgccc
     2941 acgcccgacc atccgctcac gccgcgcgtc accgatgtga atggggatgg ggcgcaggat
     3001 ctgctctatg cgttcaacaa ccaggtccat gtcttcgaga acgtcctcgg ccaggaggac
     3061 ctgctcgcgg ccgtgacgga cggcatgaac gcgcacgatc cggaggacgc cgagtacctg
     3121 cccaacgtgc agatccggta cgaccacctg atcgatcgtg cgcggacgac ggcgggcttc
     3181 gaggacacga cgggaatccc gtcacccgag cagcggactt accgaaccct ggagcacagc
     3241 gatgaggacc agtgccgcta tccggtgcgg tgcgtggtcg ggcatcggcg ggtggtgagc
     3301 ggctatgtgc tcaacaatgg cgcggatcgg ccgcgcacat tccaggtggc ctaccgcaac
     3361 ggccgtcatc accgcctggg ccgaggattt ctggggtttg ggacgcggat cgtgcgtgac
     3421 ctcgacaccg gcgcgggcac ggcggagttc tacgacaacg tcacgtttga tggcgccttc
     3481 caggcctttc ccttccgagg acaggtgcag cgctcgtggc gctggagccc gagcttgccg
     3541 ctggatgcgc acagcgcgga gccggtgtcc gtcgagctgc tgacgacgcg gagctacccg
     3601 gtggtgattc ccacgcaggc ggggacgtac ttcacgctct cgctcctgga ggggaagagc
     3661 cgtcatcagg gcacgttctt gccaggaggt gggaaggggc tcgaagagag cgtgagggat
     3721 ctggagggcg atctctcgac acggatgagc gacacgctgc gtaccgtcag cgacttcgac
     3781 ctctacggga acatcctcgc cgagcagacg cagaccgacg gcgtcgacct cgagctcacg
     3841 gtcacacgca gcttcgacaa cgacccgctc tcctggcgcc ttggagagct gacgcgagag
     3901 acgacgtgca gcaaggcggc cggcgagacg cagtgccggg tgatgcaccg gagttacgac
     3961 gggcgcgggc atgtccgcat ggagcgcgtt ggaggagagc ccttcgaccc cgagatgcag
     4021 ctcgatgtct ggttctcccg ggatgcgctg ggcaacatcc acaacacccg ctcgcgcgac
     4081 gggaccgggc aggtgcgcgc gagctgcatc agctacgacg cgctgggctt gatgcctcat
     4141 gcgcatcgca atctggaggg ccaccagagc tacacacgct acgacccggc gctgggcgtg
     4201 ctgcaggcgt cggtggatcc caatggcctg gtgagtcgct gggcctacga tggcttcggg
     4261 cgggtgacgc tggagagcct cccggggcgc atgcccaccg ccatccggcg cacgtggacg
     4321 aaggacggtg gagcggctgg caacgcctgg aatttgaaga tccgcacgtc ctcggcgggg
     4381 ggccaggacg agaccgtgca gttcgatggt ctcgggcggg aggtgcgctg gtggtggcaa
     4441 gcgctcgacg tgggggaaga gcaagcgccg cggatgatgc aggaggtcgg cttcgatgcg
     4501 cggggcgagc acctcgcctg gcgttcgctg ccgatcgcgg ctcctgcgcc accaggctcg
     4561 atgcaggtgc gagagacgtg gcagtacgac gggatggggc gggtgctccg gcacgtcacg
     4621 ccgtgggggg cggcgacgac gcacgagtac atcgggcggg acgaggtcat cacggcgccc
     4681 gggcaagcgg ttacccgcat cgccagcgac gctctcggca ggcccacggc ggtgggcgat
     4741 cctgaaggtg gagtcacccg ctacacctac ggtcccttcg gcggtctgcg gacggtgacc
     4801 acgcctgctg gcgctaccac gctgaccgag cgcgatgcgt ttggccgggt gcgacggcag
     4861 gtgagcccgg accggggggt ctctactgcg cactacgatg gctacgggca gaaggtctca
     4921 tcgctcgacg cggcaggccg tgaagtcacg accagctacg acacgctggg tcggataacc
     4981 aggcaggtcg acgaggacgg cgtcaccgag ttccggtggg acgatgctcc gcatggcgtc
     5041 gggcagctcg cgctggtggt cagtccggat ggccatcggc tgcgctacgg gttcgaccac
     5101 ctcgggcgac cagcgacgac gacgctggaa ctcggcgggg agagcttcac cagccggctg
     5161 tcctacgatc tgagcgggcg gctcaagcgg atcgagcacc cgagcgcgcc agggatcggc
     5221 agcttcgctg tcgagcggga gtacgatccc tacgggcggc tgcgggcgct gaaggacgcg
     5281 gggtccggcg cggagttctg gcgggcgacg gccatcgatg cggggaaccg gatcacgggg
     5341 gagcgcttcg gtggagggac cgcctccacg ctccgcacgt tcgatgcggc acgagagcgg
     5401 gtgagccgca tcgcgacgca ggcggcgggc gtgcctgtcc aggagttcgc ctacctctgg
     5461 aacgatcgcc gcaagctcgt cgaacgctcc gatggcatcc acgccaacgt cgagcgcttc
     5521 cggtacgacc tgctggaccg actcacctgt gcgcagttcg ggctgatcaa cgccgccctc
     5581 tgcccgcgac cgttcatcta cggacccgat ggcaacctgc tccagaagcc cggcgttggc
     5641 gcctacgagt acgaccccgc gcagccccat gccgtcgtcc gagctggtag cgcgttctac
     5701 ggctacgacg ccgtgggcaa ccagacctcg cgaccaggcg cgacgatcgc ctacaccgcg
     5761 ttcgacctac cgaaacagat ctccctcacc agcggcgaca ccgtcgacat tgagtacgac
     5821 ggcctccagc agcgggtgcg caagaccacc gcgacccagg agatcgtctc cttcggcgag
     5881 ctgtacgagc gcgtgaccga tgtcgtcacg gggaacgtcg aacaccgcta ccacgtccac
     5941 aacgacgagc gggtcgtctc gctggtgcgg cgctcgacag cacagggcac gcgcacgctg
     6001 cacgtccatg ccgaccacct cgggtcgatt gacgtgctca ccgacggtgt gaccgggagc
     6061 gtcgccgagc agcgcagcta cgacgccttc ggcgcgccac gccaccccga ctggggttcg
     6121 gggcagacgg cgtcacccca cgagctgtcc tcgctgggct tcaccgggca cgaggccgac
     6181 ctcgaccttg gcctcgtgaa catgaagggc cgtatctacg acccgaagct cggccggttc
     6241 ctcacgccgg atccgctcgt gccgcgacct ctcttcgggc agagctggaa cagctactcc
     6301 tatgtgctca acagcccgct gtcgctggtc gatcccagtg ggtttcagga gcagccacct
     6361 gcgacagagg acggatgctc gcagggctgc accatctggg tgttcggtcc tccgcgcgaa
     6421 cccaagccgc ctgcgccacc caaggtcgtc gagggcaacc tggaggaggc cgcgggcgct
     6481 ggttcgacgc aggcgccgat cgacgtcggg acctcaggcg tgcgcggtgg gtggagtcca
     6541 cagctcccag ccacgctgca ggccctgggc cgtggcgacg ccatcgccag gcgcatcatg
     6601 gatggcgttc gcatcgggat ggccaggatg ctgctggagt ctgccaagct cggggtgcta
     6661 ggtggcacca gccgtgttta cgtcgcgtac accacgatca ccgctgcctg gaatggttac
     6721 aaggagagtg ggctgcccgg tgctctcgat gccgtcaatc ccgccagcca gatggtggaa
     6781 gccggcgtgg aggcctacga cgccgccgcc gcagaggact gggaatccgc gggggccagc
     6841 ttgttcaagg cgggctcgat cgggatgtcc atcctcgcca ccgctgtcgg ggtggggggc
     6901 gccatctccg cgaccatcgg atcgacggca cgcaccgtgg gaagggcgtc tgtcggacct
     6961 acaaggggcg gtgggccggg agcccgcccg agtcagccct tttcgaaggc cgggaaggac
     7021 gaagtatgga aacagaacgc gacgaagcac agcggcgtca acaagtgcga aaactgcggc
     7081 agcgacgtca tcaaacctca gcagcataca aagggggtca ctcccccaac caacgaggga
     7141 catgtcgacc acgtcaccgc gcgtgtgaag ggtggttcag gaacgcctga taatggccaa
     7201 gtgctttgtc gcggctgcaa tctggagaag ggagcccagt gatttctgct ttcaacgaga
     7261 atccccgcct cggagtcttg accactgctc cagttttggc tggagcgccc atcatgatgg
     7321 tctctcacga cgccgatgat ggggggtggc aattcctgtg tggcacaaca actgaccctg
     7381 cagacgggcg tatcgttcac ttgcaagaga ttgtggacat ggacccgtct ctcactgtgc
     7441 tggcggacct tccgagcgga tgggttgcct ttcgcaccag cgtcgatggt gagtggacga
     7501 gggaacgctg ttgaaatttt gcctcgaaaa ataaccagga ctgtcagcga ccgttcacct
     7561 acggacccga tggcaacctg ctccagaagc ccggcgtcgg cgcctacgag tacgaccccg
     7621 cgcaacccca cgtcgtcgtc cgagctggca gtgctttcta cggctacgac gccgtcggca
     7681 acaagacgtc gcgaaggcac tggacgacat cgagggcgcg accggtacac gtccccgatt
     7741 tcacccttac aactgagagc aaccatggga catcaggtga atttctacgt cacgccggcg
     7801 gacgtcacac agctgcacct gcgcatcagt gagatcgaac cgatgcgcat tctccacgat
     7861 cgttcagcca cggccgaacc acgggaagtg cgcagtctca acttggtaga agagacgcaa
     7921 cccttgcttt tctacttcct ggtgcgtgag cgcgacctgg caaagtcgtc accgagcaca
     7981 ttcctgcaca ggggtgctcg acggtggact acctacgatc cccagtcgtc cagttcaaca
     8041 gctgctactt cgacggcaaa atccttcggc gcggcgggtg gagtccgcaa ctcctggcca
     8101 cgcagcaggc cctggaccgt ggcgacgcca tcgcctggcg catcctggat ggcgtccgca
     8161 tcgcaatgac cagaatgctg ctggagtccg caaagctcgg catcctgcgc ggcactcccg
     8221 cgagccgaag tctgcctcct cggcgatgaa cagcgcgccc gtcctcccga ggcaggcgag
     8281 gacgggcgcc ttcattctca cgagcggcct actggccctc gtgcatcacc ccgcggccgg
     8341 cgtcgctccc cccgtcatcg acggcggctc ctcgtccagc gcctcctcct cctcgatccc
     8401 atcgagcccc ctctccagcc ccttggccgg agagcctccc agcggcggcg tcgacgaccc
     8461 ttgcgctgcc gcccgcgccc tccgcgctgc ccgggccgct gcgcgctgct ggagccgctg
     8521 cccctcgtag ggccccagca gctcccgctg catcgccgtg ttcccctcgt agtcgacgac
     8581 cacctgcgcc gcgaagcgca cgaacgcctc gtgccacgcc acgctcgcca gctccgtcgc
     8641 gcgccctgcg ccgccggcgt cctggcccag cgaacgcccg tagcgctcca cgtgggtcac
     8701 gaggtgcagc acctcggcct ccagccccag cgcagtgacc gcagcgtcga cctccggctc
     8761 cccgagccgc tgccgcagat cggtcaggtg cttcagctcc atctccattg gcagccggat
     8821 gaagctcgtc cccttgggaa acaggcgcgt ccgcagcaac cgcacctgac ccagcacctc
     8881 gcgctgcgcc ggacccaggg gaacgagcgt gtcgagcagc atctcctcgc gcgcttcgag
     8941 catccggtga aacgccgtca ccaccgtgtc ggtggcctga tcggcggccc tcggcgggac
     9001 atcccgcaca ttcaagagcg ccagcgtcga agcgatgacg gcatctccac gggtccgtgt
     9061 cgcgccttgg agcggtgtgg ctcggggcgc tgccaggatg gggcccagcg cattcccgac
     9121 gttgatctga cggtccactt ccagacgggt cgtattcagc atgtctaaaa gcctcatggt
     9181 tctcattcgg tgaaattccg taaataagga aagctccgga ggcccctaac ctggatcctg
     9241 gagagcctcc gcgcaaggcg gacaagcacg gccagatgaa aaataggtag cacaaggtgg
     9301 gtaaacgtct gctggagctg ccgaggccat ggcatcgcca gcgtacccgt cgcgccgcgt
     9361 gggccaccgg atgcagaccg ctcgaagaag ctcgaatcta ttggcttttc ttgctgccac
     9421 cgtgcggtgg cgctcgcgga cgtcggaagc tcgcggaggt tccctgacac gcgtcggaag
     9481 ctcgcggagg ttccctgaca cgcgtcggaa gctcgccgag gttccccgac acgcgttgga
     9541 agctcgcgga ggttccctga cacgcgttgg aagctcgccg aggttccccg acacgcgtcg
     9601 gaagctcgcg gaggttcccc gacacgcgtc ggaagctcgc ggaggttccc caacacgcgc
     9661 tggaagctcg ccgaggttcc ccgacacgcg tcggaagctc gcggaggttc cccggcgcat
     9721 gctgtgtagt ccagttcacc gattgcatga agccggaggg gttgaaccat cacccgcacg
     9781 tctgggtccg tcagaatctc tgctcggctc gcgaggcgct tgggccttcg tgcttcacgt
     9841 cggcgtgaag tgccgcgttt cgtggcggtg ctgttccccc gtccatgcct cccgaagctg
     9901 gcgaagcgcc ttccatgtcg ctcgtacgcc gtcgatgtcg ggatgccctg cgcgacaggt
     9961 gatcgcgtcg catgcgaggc gctccagccg cagagagcgc tcaggcaggg tctgtcgccc
    10021 gcagacgacg cgccccctgc gcaatctgct cccacgcctc ggtatgctgg aagtgatagc
    10081 ggacctgttt gggcgtgatg cccgacttca cccgccgatc catcgtgcgg agcagttcga
    10141 gcgcgtccag tcttttccga tcgacgcgcc gctcgggcag atagctacgg agcgccgcga
    10201 tctcgctgtc cagcaggccc gcatcgctcg cgctcccgag cagcgacggg tagctccggt
    10261 ccgcatagaa agacgatctg gcgagcccga tgagcttctt ctgcgtatcg acaccgatca
    10321 cgccatcgcg aaccgcaccc gcgagcgtcg cgcggatgtc gaccatggcc accgacagcg
    10381 gtcgatagcc gccctcggcc ggcgcgtggg ccgtggcgac ctcgtcgtcg gcgtcgatgt
    10441 ggccgcggcg gaaggattcg tagacgtctc cgatgccctc catgccgaat gtcgccagct
    10501 cggcggcgcg cagggcgccc atgctcgccg cgccgaacac gtggatgccc tctttcatgg
    10561 tccagaggat ttccttgtgg gagacggacg ggacatgatc gaaatagccg tcgatgattc
    10621 cgatcgctgc gggtcgttcg cacgcggcgc gatagacgtc tccttgcgct gccgggggca
    10681 ggtacgtggc ctccagcacg ccgctcgcct cggtgacgga gagcgtgggc ccgaggaaaa
    10741 tgaccacctt cattgcacgt tctccaggag gcgcctccgc gctcgcgcgc ctggcctgta
    10801 cccgggcaca tcgctcaaag gttcgaggcc cgggacgatc acccgcacga ccgggatctc
    10861 gaagaggtcc ttggtcaggt ccacggccac cacctcctcg atgccgacgg cgcgcagccg
    10921 ctccaggagc tgtgccaggt cgtcgtcgaa ggactcgttc cacctgtctg gcgtctcgtg
    10981 aaagtgtcgc gtgcggggct cggcggcgag cgcagccgtc atcctccgcg ccgcctcgac
    11041 gtcgcggctg gcgctctgcg gggcctgatg aagcacatcg tcgcgtgagc ccgtgatgag
    11101 cgtgaggcgg ctctgggcgg cttcggtgag ggcgcgcgag agtgccaccg cgcggctgag
    11161 gtgacagccg aggccaccca tcgggccgat gaggcggttc gggtttggct ctcggtcgac
    11221 gatggtgcac atgaacgccg ccacgccgac gtcggaggtg gtgtcccaga tggccacctc
    11281 gacgcccgcg cgctcgtaca tgccgagcag ctcgcgacag ccggcatcgt ccacggtgtc
    11341 gggatcgacc cggcggctcc gctgaatcgc ttccgtcgag ctccgatgca gcgtcgtgca
    11401 atcgtgctcg atgagttcgc acaaggcgtg agccagcgcc tcctgagggg cgttcccgga
    11461 ggccaggccg cgggagctca tcaaaaagga cccgctcccc gaaggaagtg gcagcgtgta
    11521 gtccatgtgc accatctcgt gaggcaccca cgtcgacgcg ccatcgagca ggttcgtccc
    11581 ttcgatccac agcgtgcggt agttctggtg aaactggccg accaggagcg ccggcagggc
    11641 ggcgacgccg accagccggt gggtgaaccg cagctcgttg aaggtggcga gcttgagggg
    11701 ccggtcgatc tgctcggcgt gccagagttc gagcgactcc atgaggcccg aggccctcgc
    11761 ggcgtccagg tccatgccct ttccctggga aacagagagc gaacgcgcgt tgggccggac
    11821 gaccatcacc acgggaatgc cgatcgtatc gagccccgtg acgtcggcga tccgggtgat
    11881 gcccgtgatg ggcatcatcc gtcgcattcg ttccaccgtc tcggtcgggg tcacgaggcg
    11941 gtgggtgcca gcgagatgac gcttgatggc gggcatggat ccattccttg ggatgcgcag
    12001 ggcgtcagtc gccgtccggt cccgagtgtg cggctggaat ggtctgactc agcgctttca
    12061 tgttcagcac gaagcacgtg acgaagtaac tgggaacgcc gcgcggggct gggggctcga
    12121 cccagctcac gaccgtccca tggtgcgcca gtacgcccac ttcggctgga ccgctctcca
    12181 tcgaggcgaa gctccactgg ttcttcgtgc tcatgtcgat gaaccagtac tcgccatccg
    12241 ggccatacac gatcatcgtc ttcttcggat cgcatcgatt gttcgtgcac acgtacacat
    12301 cggtcctggt ttcgtacgtc tgaccttctt cttcgtaggt cgccgtgatg gtcccccgga
    12361 cgaggagggg aagctgcgct gctgtctccg tctgctctgc cgtctccgga tcccccgctg
    12421 gatcacgcgt cagcgtgacc gattccacga tcaacatccc ggccagaccc agaccctcca
    12481 ggcattcatg ggtcggatcc ggttggatca cgctgtattc gacgtcaatg gccgtgcctt
    12541 caccctcgcc tgcaacgcga ggaaagacga cgtcccatcg ggccttgacg cttctggtgg
    12601 acaggtcgcc gttgcatccc gtcgacagag aagccctcag tggtatgcct tgcccctcct
    12661 ggctcaatcg aacgatggcg ttcgtcgggt cgatgttcag ctcgggtctg gggtaaaaac
    12721 agccgtctcg gcatggttcg atctcgattc ctggtttgcc atcacgtgct ctccttccaa
    12781 tgagtggttg acgggtccac cacgctttca tgcctcggag attgcgatgc gtgacgtctc
    12841 cggcgagcgc agggagagca ccgcctcttc cgtgcagctc cagagagcgg caatgcgtaa
    12901 ggcggcgctc ggcggaacga ccgcagctct ctgcgccatc gacatcacac cattccccgc
    12961 gtcgcgtcgt gatggtttcg ctgcgctcgg gcctcacgtc cagtgaagag cctcgatcgc
    13021 ttcaggacca gccgtatcag gcacacatgg gcacgccaag agtgcgcgtc gtcgccctga
    13081 tcccgctact ggatcatcga tctcggtcgt gacgtcatgg cattgcctcg ctcgctttgg
    13141 agaagctccg gtctctcgtg cattggttcc cgtaatgcct ttccgggagg tgccgattgc
    13201 tggctcgacg tgggcaccct cgtgagcgac gcgcaggtgc tccgcgcgct cgcgcgctcg
    13261 ctcacgagct gatgccacac ttcggtgagc tcagtggctc ctcgctcacc tcaggcgtga
    13321 ggggtcgaca gcaacaggcc cggaccgatc gacgcgacgg tcaacgctgc gcagggtttc
    13381 gtctaccatc tcctaccaac acctgcctgc gtcatcctcc acggacgttg gaggcctggt
    13441 gggcacaggg catttgaaat tcaatttcaa tcgtgacggc cgcgcgccag gcggaggtgc
    13501 cttgtgccca ggacgacatc gtttcgtgac ggtggtgcga tctcatcgat gtctccccga
    13561 gctggagcct cggcttcgcg tgccacccgt acgccgtggc ggtcgagctg tcctgaggct
    13621 cggcgctctc gatactcgga gcgccgtcgc gatcctgagc cgtgagcgcc gtcgcgatcc
    13681 tgagccgtga gtgccatcgc gatcctgagc catgagcgcc gtgcgcgggt ccgtgtccac
    13741 gtgctgagcg cagatccgcg tccacggctg agcgcagatc cgtgtccacg tgctgagcgc
    13801 agatccgcgt ccacgtgctg tccgtgagcc ctgcgcgatg cggaaatcag cggccggtgc
    13861 gcggtcgctc acaccaccgg agcgcgcagc agggttgcac ggagagcgcg caggcgggtc
    13921 atgctgggca gaagcctccc gtatggcgca cgcatggcgc acgcgtgacg ctcgcgcggg
    13981 atgcacgcag gggcgataag ccccgcgcgc tccgcgagcg tgacgagcgc tggggcgaag
    14041 agtcccgcac gaggggcgtg cctcggtgcc ccctggtgag gtatgcgggg tgcatcgtgt
    14101 cccgggtgtc gcgcatgctg gactgcgcca gttgaagcgg tgcgtcgagc tgcgcatcgg
    14161 gcgtcggcgg atgcccacga cctgcaaccc gtgagaccgg agagcagccc gtttgcggcg
    14221 ggcgcgctat cctggagggg acttcatggc catcagcgtc ttcgatttgt tcaagatcgg
    14281 catcggaccg agcagctctc acaccgtcgg ccccatgcgc gcggcgcgct cgttcgctct
    14341 tgcgctgcac gaggcgggct tgctggaccg gacggcggcg gtgcgctcgg agctgttcgg
    14401 atcgctcggg gcgacggggc gggggcacgg cagcgacaag gccgtcatcc tcggcctgct
    14461 cggcgagacg ccggacgagg tggacgtgga gcgggtggac gacatggtca ccgaggtgcg
    14521 gcgcggcggg gccctgcgtc tcctcggtcg ccgcgtggtg gccttccgtg agccggcgca
    14581 tctcgcgctg gtgcggcgga gcttgccgca tcaccccaac gggatgcgct tcacggccct
    14641 ggacgagacg ggggcgtcgg tgctgtcgcg cgtctactac tcggtcgggg gaggcttcgt
    14701 cgtggacgcg ccggagccgg tcgacgaggc cgggtcgacg tcgtcgcgct cgcccaccgc
    14761 cctgcaaggc gcgcgggatg cggaggactc gtcgctgccg cacccgttcc ataccggggc
    14821 gcagctcctc gcgcgttgcc aggcgtcgga gctctccatc agccagctca tgctcgccaa
    14881 cgagcgcgtc acgcgctccg acgcggagat ccgcgccggc ctggaccgca tctggcaggt
    14941 gatgcagacg tgcgtccagc ggggctgccg caccgagggc atcctgccgg gagggctgaa
    15001 ggtgcaccgg agagcgcccg cgctgtaccg caagctcatg gatcacccgg aggcagggct
    15061 ccgtgacccg ctcaccgcgc tggactgggt gagcctctat gcgctctccg tcagcgaaga
    15121 gaacgccggg ggagggcggg tcgtcacggc gccgaccaat ggggcggcgg ggatcatccc
    15181 tgcggtgctc cactactatc gacgcttcgt gcccaccgcc acggacgagg gcgtgcagcg
    15241 gttcctgctc accgcggcgg cgatcggcgt gctttacaag gagaacgcgt ccatcagcgg
    15301 cgccgaggtg gggtgtcagg gcgaggtggg atcggcatgc tccatggccg ccggggcgct
    15361 gtgcgaggtg atggggggct cacccgcgca ggccgagaat gccgcggaga ttgcgatgga
    15421 gcacaacctc ggcctcacct gcgatcccat cggggggctg gtgcaggtgc cgtgcatcga
    15481 gcgcaatgca atggccgcca tcaaggccat caatgctgcg cgcatggcat tgcatggcaa
    15541 cggccagcat ttcgtgagcc tcgacaaggt gatccggacg atgcggatca cgggtgagga
    15601 catgaaggac aaatacaagg agacggcccg cggtgggctc gccgttcgtt tcgtggaggc
    15661 gcccgccgac gtgagtgtcg gattgccgga gtgctgagcg cacgacgtcg gacggggtgc
    15721 aacctcgaca ccatttcgcc accattccgt cggatgtgaa aagcgcgggg tgtgtgtcct
    15781 gcccctctgt gcaatttctt ccactgagcc agactctcgg gcgctcatgg attcatctcg
    15841 tgaggcgtat gtggtgtcag cccacaatac gcgttcatgc cccattcctt gcattcgctt
    15901 tgctgtgtcg ccgtcgcgac ggctgggcat aagctgagct gggaggattg tcttatgacg
    15961 actaccgaag cggctccggc gaagtcgata cgctcggttg aactggacca gaccatgctg
    16021 acctgggaga cggacagcgg tctgctgggc caccacggcc gccgctccgc catgttctgg
    16081 ctggagccct cgctgttcca gcttctcgcg ccgctcgtcg aagagctcgg ggtcccgctc
    16141 tttcgcctca ccgtcgcgta ccacgcgagc cttggcgctc gggacgatca ccgcatcagc
    16201 attgcgaacg agggggcctg tttcccggag gtgctggagg ggtgggggcg ctcggtggag
    16261 gtctgcggct ggggaaaatt cgagctgaag tggttcgacg aggaggcgtg tcgcgcgctg
    16321 gtgcgggtgc atcacccgtg ggagctggcg gtgcagcgcg ccgcgaagga gcggtggggg
    16381 agcccatttc tgttcggcaa gctggtgggc ctgttttcgc tggtgagcgg gttcaattgc
    16441 tgggccgacg aaatggaagg ggaggacgag aatggcgtgc ccatcgtcga ctttctgctc
    16501 taccgctcgg accgcaccat cgaggaggaa ctgaagattc tgcggcgcga gcacgatgag
    16561 gaggcgaggc ggccgctgcg gcagaagatg caggagctgt gggagagcaa ggagcggcag
    16621 cgggcggtgc tcgcgtcgct gggggaggtg gtgctgacgg tggaccgggg gggaaggatc
    16681 acgagcttcc acgtcccgcg ggatcaggcg gcgtttcacc cgtcgccgga gctggcgatc
    16741 ggcaagaggc tcgaggaggc gctgcctccg gacgtggccg cggccctcgg ggaggcggtg
    16801 cagcaggtgc tgggggggga gccgcacctg ccggcgagct acgagatcgc ggccgcgggg
    16861 gaggtgaggg gctacagcgc gaagctgacc tcgatccacg atgccgctgg tgcggtggtg
    16921 ggggtgacgg tgctggcgcg cgatctgacg gagcggctcc ggatcgagcg cgcgctggag
    16981 acgcagctcg cggtgatcga gcagcagcag gaggcgatcc ggatgctgtc cacgcccgtt
    17041 ctccaggtgt gggatggggt ggtggcgctg ccgatcatcg gcggggtgga cgagcggcgg
    17101 gtggccgaca tcacggcgac gctgctggac acggtggcgc ggacgcaggc gcgctacgcg
    17161 atcctcgacg tgaccggggt ggacgcgatc gaccggcgga cggcggatca cttcacccgg
    17221 atccggcggg cggtgacgct gctcggcgcc gagtgcctgc tctgcggcat gcggccgggc
    17281 gtggcgcagg cgatggtggc gacgggcgtg gagatggatc aggatcgcgg gccccgtgcg
    17341 cggaacttcg gcaccatgca ggcggcattg caggctgtga tcggtcggcg gtgacccctc
    17401 ctgccgaggt gtcgcggcgg ggtcggagcc ggagcctcat gcactacgtc gagcatcccc
    17461 ctgcgccagc ccttcgcgag gtcgtgcgct gtctctggag ccacgagggc gtgacgggga
    17521 gcgtgccctt ccacgtgctc cccgacggtt gcctggacct ggtgtgggac ggcgtggcgc
    17581 tgaaggtggc gggcccggac acgaggccct ttctgacgac gctgccggag gggtacgcga
    17641 tcacgggact gcgctttcat ccaggggtgg cgccgacggc gctgggggtg cctgcgtcgg
    17701 cactgcgtga cagccgggtg gcgctggagg atctgtgggg cgtcgaggcg gtgcgtctgg
    17761 ccgaggcgct gggcgaggcg ccgtcgacgg acgcgaagga ggcgctcctg gcctcggccc
    17821 tcgcgcgacg ggtggtgagt gcgccggcgc ccgatcgcct cgtgaaggcg ctcgtggggc
    17881 ggttcatgcg cgtcgtgggg gaggccagcg ccccgcctcc ctcggtggag ctgctggcgg
    17941 acgagctggg ggtgagctcg cggcagctcc tgcgccggtg cacggacgcg gtgggttacg
    18001 ggccgaaggt gctgctgagg gtgctccgct tccaggagtt tctccggcag gctcgtgcgc
    18061 agccggcact cccgctggcc cggctcgccg tgagctgcgg gtacacggat caagcgcacc
    18121 tcgcccacga ggcgatggcg ctcggaggga agacgcccgg cgcgctgcgc ggggtcgtgg
    18181 acgggtgagg cctggtcgct ggctgctgcg cgagggcgtc gatggggggc gtccgattct
    18241 tacaagcgag gggcgaggga gggcggcacg ctgggggcat gcgacacctc gatctttcgg
    18301 ccctcgaggc ggccgagcgg ttcgtctggc tctccggtcg tgtgctggag cggttgcgct
    18361 tcgctcacct gttccgtcat ggcgacgcgg cgcgcgtgct ctccgcgctg cggccgtacc
    18421 agaacccgga cgggggtttc ggtgaggcga tcgagcccga cttccggggg ccggtgagcc
    18481 agcctctctc cgtggacttc gcgctgcaca tcgtcgacga ggtgggcggg ttcgaggatc
    18541 cgatggtcgg cgcggcgctc ggctacctgg cctccatcac ctgcgaggac ggcggggtgc
    18601 ccaatgtgct tccggacgtg ccgcgctacc cgcacgcctt ctggtgggcg ccggcgcctg
    18661 ggccgctcgt gggatcgttg ctcccgacgg cgtcgatcgc ggggctgctc cacaagcacc
    18721 gggtggcgca cccgtggctc gagcgggcga cgtcgttctg ctgggaggcc atcgaggggc
    18781 tgccggcgcg tgtggcggtg gcggaggggc gcatccctcg gctccagatc gcgtacgaga
    18841 cgcgggccgc gctggtgttt ctggagcacg cgccagagcg agcgcgggcg gcgcagacgg
    18901 cgcgggcgct gggcgagctg ctgctgggtc ggggagggtt catcgcggcc ggcgagggga
    18961 cggcggggga gatgtcgttg ctcgatgtcg tgtcgcgccc gggctctcca gcgcgcgcgt
    19021 ggttctccga tgcgcaggtg gagcagcacc tcgacgcgct gctggccgag caagggaaag
    19081 agggcgggtg gtcggtgagc tggccggcat ggacggcggc ggcagggctg gagtggatgc
    19141 cgatccagac ggtggagcgt ctgaagacgt tgaaggcgta cgggcgcttg acgctgcccg
    19201 cggcgggcgg gtgagtgcag gaggagctgc gggggcgcct gacggcatcg tcgtcacatg
    19261 ccttcgtggc gggcagaagc ggcacagcgg cgtggtgcgt tgcaggcagg tctggctccg
    19321 aaggggacag acggggcgac gaggtgtccc cggcacagcc agacagaccc cggcatatgg
    19381 cttgctccac gtgagggggc tccacgagag aggcggagcc aaccgggccg agcgcccggt
    19441 aaatccctgt caattcacga agaggagact gtcatgagca acgaaagcaa gcgcgccgag
    19501 ggagcagcgg aggaactcgg gggcaagatc aagaagggga tcggtcagct catcggcaac
    19561 gagcagatgg aagccgaagg cgccgccaag gagctgaagg gcgaggccaa gcaggaggca
    19621 gccaaggcgg ccgagcgcgt caagggggcc atcgaggagg ccacgggggc gatcaagaac
    19681 cgcgtggggc acctgatcga caacgagcag atgcaggcgg aggggcgcgc gcgtgagctg
    19741 aagggcgagg cgcgccagaa ggcgaacgag tagctcgcct tctcatcgac gtcgcggcgc
    19801 ggggttcggc ctttactggt cgagccccgc ggccgtttcg acggtcggat ggcgcgtcgg
    19861 tcggaggggg cgtcggtccg gtggcggggt cgggtctgtc gcactctggc cgaggaaggc
    19921 ctacaggctg gcggggctcg cgggggtcgc ggcggtcggg agggggtgga gatcgcggag
    19981 gacgcggagg acgcggagga cgcggcgatc acgggcaagc gagcgacggt gcggcgctca
    20041 tcggtcgggg accatcggtc ggggaccatc ggtcgggtga cggtgtcgtc gtcgtgcgcg
    20101 aacggcagcg cgtggctgtt cgtcgctgta tcctgcaagg tcgagagagg gaggcctttg
    20161 tgcaggaaca gacgatcggc ggatggagcg cggatttcat gcgggagctg ccggagaagc
    20221 cgagcgcgca ccgcgaggac gccattcttc gggcagcccg cgacaatcgc ctggcgccca
    20281 tcacctggat ggaggtgacg agcaagaaga acaaccgcac ggtggtgctg ttcgtgagcg
    20341 ccgatgcgct gcggctgggc gacgagcacg cgtcggtgcg ggtcacggtg agcgcgagga
    20401 cgacgcagcg gatcgccgat gcgctgggct gcgtgctgcc gacgacgaag atctgtgacc
    20461 tcatctggga gcaggcagcg gtgaagctcg cgccctgcat ccagtcgccc gacaaggcga
    20521 tgggctacac gtcgcggatg atccagcacc acgaccgcgt ggagaaggcg cgcgcggggc
    20581 gccctgggct gatcgagaac gtgggcaagc actgggtgct cacgaaccgg ctggcgagca
    20641 agcgcgatgc gtcggcgaac tacggctggt acgaccaccg ggcgccgtac ctctcgggca
    20701 agcaccgcgt gtggcagccg ctcgggctgg cgcacaacct ggatcacgtg gattactcgc
    20761 aggtggtgcg gctggtgcag cagtgctgtc tggtggacgg ggaggagcgg gatctcaagg
    20821 aggtgctggt cgaccgggag ctctcgccgc tggtgtcgaa cgaggggccg ctgaagttca
    20881 cgcggttgcc aggggtcaag ctcgacgctt gatgggcgtg cgcgctgcgg cggcaaaagt
    20941 gcagcgatga ggccggttcg gtggtgccac ggtgggtcgt gcgccttgct cgccgcgctc
    21001 gctcttgtat ggtgctcccg aggagcgagc ggggagcggg ctcagggagg cgccggagat
    21061 ggttgtgacg ccgggttcca tcgtgggagg gaagtaccgc atcgagcggc ctctctcgcg
    21121 cggtgggatg ggagcggtct gggcggcgcg gcacgttctc ctgggctctc cggtcgcgct
    21181 caagctgatg gatcagtcgt tcgcgtcgtc tccggcgttc gtcgcgcggt tcgagcgcga
    21241 ggcgcggacg gcggcgcagc tcgagagccc ccacgtggtg cgcgtcgcgg actacggcgt
    21301 ggaggacggc acgccgtacc tcgtgatgga gctgctcgaa ggggaagact tgagcgcgcg
    21361 gctcaagcgc gtggggcggc tgtcgttgat cgaggcgacg gagatcgtcg cgcaggccgg
    21421 gaaggccgtc cgacgggccc acgccgcggg gctggtgcac cgcgatctca agccggggaa
    21481 cctgttcctc gcgcaggtcg acgagggcga gatcgtcaag gtgctcgact tcgggatcgt
    21541 gaaggagacc cggggacaga tcctcggcga ggtgacgcgc acgggagagg tgctgggatc
    21601 gccgcacttc atgagccccg agcagatccg gggggagcga aatgtggatc accggagcga
    21661 tctctggtcg ctcggcgtca tcctctaccg ggcgttgacc ggcgtgctgc ccttcggtgg
    21721 tgatcagctc ggggcggtga tggcgaagat cctgatcgat cccttcaccc gggcgacgca
    21781 gctcgtcccg gagctgccgc cgcagatcga tgagttcttc cagcgggcgc tcgcgcgcga
    21841 tcggctcgtg cggttccagt cggtccggga gatgatcgag gagctgcagc gcatcgccgg
    21901 ggtgcccagt cagctcggcg ccggggactc gtacgggcac agcatggtcc cggtcggcgc
    21961 gacgacgacc ctgggg
//
