LOCUS       NZ_CP012159            20942 bp    DNA     circular CON 02-MAY-2024
DEFINITION  Chondromyces crocatus strain Cm c5 chromosome, complete genome.
ACCESSION   NZ_CP012159
VERSION     NZ_CP012159.1
KEYWORDS    RefSeq.
SOURCE      Chondromyces crocatus
  ORGANISM  Chondromyces crocatus
            Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae;
            Chondromyces.
REFERENCE   1  (bases 1 to 11388132)
  AUTHORS   Zaburannyi,N., Bunk,B., Maier,J., Overmann,J. and Mueller,R.
  TITLE     Genome analysis of myxobacterium Chondromyces crocatus Cm c5 reveals
            a high potential for natural compound synthesis and the genetic
            basis for the loss of fruiting body formation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11388132)
  AUTHORS   Zaburannyi,N., Bunk,B., Maier,J., Overmann,J. and Mueller,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2015) Department of Microbial Natural Products
            (MINS), Helmholtz Institute for Pharmaceutical Research Saarland
            (HIPS), Campus E 8.1, Saarbruecken, Saarland 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Newbler v. 2.6, HGAP SMRTPortal v. 2.2.0
            Assembly Name                     :: Cm_c5_Newbler_HGAP3_v13
            Genome Coverage                   :: 366x
            Sequencing Technology             :: Illumina, PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001189295.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 07:18:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,280
            CDSs (total)                      :: 8,172
            Genes (coding)                    :: 8,124
            CDSs (with protein)               :: 8,124
            Genes (RNA)                       :: 108
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 96
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 4 of 48
            Pseudo Genes (incomplete)         :: 44 of 48
            Pseudo Genes (internal stop)      :: 3 of 48
            Pseudo Genes (multiple problems)  :: 2 of 48
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:43:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3644670
            Orig. end                         :: 3665612
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012159.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20942
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20942
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20942
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10942](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10942)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            216..1487
                     /locus_tag="CMC5_RS13625"
                     /old_locus_tag="CMC5_027610"
     CDS             216..1487
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS13625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_027610"
                     /product="hypothetical protein"
                     /protein_id="WP_050430822.1"
                     /transl_table=11
                     /translation="MLVECRFCGAPLDVSGTTPLVKCRYCEKTSQLRSLRTMVPRTPPN
                     WTPPPQWTPPPHLHFPTTKPLAYHHDFVRMQYVVVLGVMLLALVVGLLSSGGTSKKRPH
                     RGVKRETILSTPMRGGCVVAEASTHVSPDAKGEIHVEVDDDLVPRMTFQCSPEKVEPLQ
                     RISIHLRDARKHDARIQTRLRALFGRRFLQSSLSWEGASVQWLPELGLLTVDVKRTLDD
                     GSENPHRVQQIEALWGLAKELAFQAPATLDPQTVRDYLGGGYALSALATLDPKTPVERS
                     VSTLSARFRGLHTRTLGDLHGFVEEEQRLAIDHPWFGLATLRWDGRPGSPLKTISLFPP
                     TLLQGVYVQRGAIDCLTRLLGPPEAPSSRKSFSGQGAVFTWPGEGNYSVAALETSLVID
                     ARAASSAGFQRILNGLSACGQPVR"
     misc_feature    223..238
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.02"
                     /tool="antismash"
     gene            1647..2900
                     /locus_tag="CMC5_RS13630"
                     /old_locus_tag="CMC5_027620"
     CDS             1647..2900
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021509.4"
                     /locus_tag="CMC5_RS13630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027620"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_050430823.1"
                     /transl_table=11
                     /translation="MEQQAVTDRIPTEFRYWDNLSTPKAQRLRGILGALFGVDPKLTDE
                     TVRTYARSYYDADPLAESVVDEVYLPRGQAAGRRLFDQALACGVDAIPDAPPSLRRLFE
                     DLETPPPWLDEQRVALGARVFRRYGTHLYSFAGAITLEGYRESSVAKPLVLTGAYTGSS
                     ANRRFLETAAFWTDVSEPGGLDPGCRGRETALHVRMMHVFVRKRLLAHPQWQLGAWGVP
                     ISHGDALLTLLGGSFVPGYALKLLGYRTSREEIEAMMHFWRYVGHLMGVQPRWFPETVE
                     QALGLLFTSMIKGAQRSGDDGVLLARSYLASYAPTAADRWFTAWRKRWEHKLQLGYVSF
                     FLPPPSYALYGLPRPGLWRFHPLLQAPFVFARETARQHLPRLDDWLDERARRETRDWVD
                     ARLGPRRAEYRAAEPIRP"
     misc_feature    1728..1730
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2943..4934)
                     /locus_tag="CMC5_RS13635"
                     /old_locus_tag="CMC5_027630"
     CDS             complement(2943..4934)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS13635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_027630"
                     /product="hypothetical protein"
                     /protein_id="WP_050430824.1"
                     /transl_table=11
                     /translation="MAYTQFAPPLSGARGTFHASSDDYLYFLQTDGAGAGRIKKVLVPP
                     HAIVSEGAGAAFTVGTTLRLDEGSASLRRAGGSITRLNGALLCELEEPPPDLAHVDPEK
                     LRTCSYSSAPLTEDGQSERGRYYAVKTVRLGHHAIVRIYKDLVDGLTKADWVTYQLHRE
                     PMDVLSGLPGPRALTQHDGHHGVTLDSGALLYIPFDAQAPPGAHVLFDGMSSPHQIAAH
                     GDLLYVVDDAGIWQIDPRQRRSPSRIHAGIAQGVGLLVAADGETFYVAEQGQGGRLLRI
                     TGGRRAVLLEGLGDVGFLRWADPRRASLLLTRRSPANQLLRVSGLTGDEPHAEVLMDGA
                     TQDPWSAEELTPGQWFVASQEGIGRLETAPPADFGFGIGLVPFQCVVPSGEHEGKADTS
                     HLMGAPFKVENVAFGGTLVVTLDHLRARQAGAHYYRVSLAEGAALVRHDGSPELKRDAT
                     ASWVATDIPVHCVGGQSHLHALRREEDGWQSLSLAARIDSTRVPNGMATLRVELFDERG
                     VAFAAASRRLRIDNARCDAGFEGMLLNGTAAQTHCGCVGYHDKQGDTVTLRFTAAHPTR
                     PVPYTLRFYRGHAHLPSLLTSGMTAVDTVQQVTLPLHKLMNSCDVASVDVHLVVPSRVT
                     DGMSMLSHLHGEARWTCMLVPDAVLLGG"
     misc_feature    complement(4905..4907)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5597..5608
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.02"
                     /tool="antismash"
     gene            complement(5803..6879)
                     /locus_tag="CMC5_RS13640"
                     /old_locus_tag="CMC5_027640"
     CDS             complement(5803..6879)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024039.4"
                     /locus_tag="CMC5_RS13640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027640"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_050430825.1"
                     /transl_table=11
                     /translation="MSVRRPSLTTSAIHVGKLVRYAAARGIEPRVLCERVHLRPDELKS
                     IERRIPLQAYADLLAYLARTFDDPGLPVHVAQGMRLEELHVMGFVIATSKSGREALERL
                     TRYAVLLSDNASWQLDDPSGPNEATIHATAASTFSLGERLAAELSLCSCLHCFRESSTP
                     SLTPTRVTFRHPAPRDVSAHERFFGTTIEFGAPTDSFSFDRALLAKTPRGADAALSAFF
                     VNHAEELRRRTRAATALPDRVRDAIALEMNAGEPTTDTIARRLGTSERSLRRHLAAEGV
                     SFRDLLDEVRRESAEQLLREGKIAIPDVAFLLGFSDVSTFTRAFKRWCGIPPGKYRERA
                     TAQRDGSSRSSPSSPPPG"
     gene            complement(7027..7638)
                     /locus_tag="CMC5_RS13645"
                     /old_locus_tag="CMC5_027650"
     CDS             complement(7027..7638)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS13645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_027650"
                     /product="hypothetical protein"
                     /protein_id="WP_050430826.1"
                     /transl_table=11
                     /translation="MHRTIRHALPLVALSLGLCALTACSSSDDGQGKTTGGQPEPEPDL
                     TGAAIFPCDDSDMIFPGAFAGPGYDPTNGGFTEPPQERYIASSTLVSIPADQMNRFFGL
                     MTPLTNQLADQPGLIGYQLALSQSCGYGRTISVWKDEESMMAFVVTDAHIAAMSEANTV
                     TSAGLVTSWELGADQIPVPWETVKAQTAKATISYGSVLTK"
     gene            complement(7691..8227)
                     /locus_tag="CMC5_RS13650"
                     /old_locus_tag="CMC5_027660"
     CDS             complement(7691..8227)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS13650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_027660"
                     /product="hypothetical protein"
                     /protein_id="WP_050430827.1"
                     /transl_table=11
                     /translation="MKRPRSPRHERLLLGLAAAAASLAALVSLQPTPFASADPSATTPP
                     SAPREAPLAPDGTSPDAPARASLSSPSPDAPARASLSSPSPDGANPLGALERTPADGAP
                     STGRVEERITTGSYVYHAVRRDDGDLVWIVSLGAGHPTGTPVKLRSMGRRTDFRSNRLQ
                     RTFPELLFGIVSRRD"
     gene            8391..10016
                     /locus_tag="CMC5_RS13655"
                     /old_locus_tag="CMC5_027670"
     CDS             8391..10016
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012321.4"
                     /locus_tag="CMC5_RS13655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027670"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_050430828.1"
                     /transl_table=11
                     /translation="MASPALALSIVLDQRGLLPATPVQAHLVAELRALGGGVERARPPL
                     SVIFAIDVSGSMVGPPLEHAARSIERLVELLEPTDRVGVAAFSDEASEVVPVARLDAEA
                     RRSISGQVHKLEAGGGTNVEAGLSLARSMMPPRGVHERQLILLLSDGAPNRGRVAVEEL
                     AAVTRGFRPEVVVSTLGYGAHHHEDVLARIADAGAGRYHFIADPAVCSVELAQALGVQG
                     DVAAEAIELSLSPGEGVELSRFHGSRELRFGASGVRVAVPDLLHGGRAVTVAELSLTPP
                     REAGVWKPLLATVTFRRAGERETQTIAATLEVPVGVTVTGPNPEARAEVLIAQADEARV
                     EARRQADRGQFEGAAAVLRGMIGTIEAEPGRGRGDGSALDEALEQLVDEAVAMERKPSR
                     EAYCAFRKAQVQSRSLAEGAESYASSPMSARMVESVAGALPRASLVVVEGDEPGKRFPL
                     SQPRNTIGRTQAAQVRIVDVNVSRMHAMIVGQEGKFFVSDLGSTNATWLNGEVLEKPVP
                     LGPGDVLRIGDVELRYEEGAQSSL"
     gene            complement(10001..10942)
                     /locus_tag="CMC5_RS13660"
                     /old_locus_tag="CMC5_027680"
     CDS             complement(10001..10942)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="CMC5_RS13660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027680"
                     /product="hypothetical protein"
                     /protein_id="WP_050430829.1"
                     /sec_met_domain="T1TS (E-value: 6.9e-78, bitscore: 261.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METNGRPLLSYPFPPALHPLAEPINRATIDWTHRVGIMPTEPAAQ
                     RRHEEYGWFGGRIYPTASEEQLDLASCFLAWLFLADDQLDETLLGRETTQVAHLHTRFD
                     SILGGAHARPDDVPLVHALEDILVRLAKLASAPLLERFCRDVSAYFEANRWECENRRRH
                     NVPCVAEYVAMRPFTGAVIPCFDLIYLTNQVDLPERLHAHPLVQATQLAANRVICYSND
                     ILSLGKEIRHGDVNNLVILIQHEQRCSLNDALHRAAALHDAELATYLSLERSLTAFEEP
                     VASHLARLTAGLRSWMRANGDWSERAARYKDD"
     misc_feature    complement(10935..10950)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     misc_feature    complement(11073..11085)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    complement(11088..11101)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.37"
                     /tool="antismash"
     gene            11149..12879
                     /locus_tag="CMC5_RS13665"
                     /old_locus_tag="CMC5_027690"
     CDS             11149..12879
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012236323.1"
                     /locus_tag="CMC5_RS13665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027690"
                     /product="cation:proton antiporter"
                     /protein_id="WP_050430830.1"
                     /transl_table=11
                     /translation="MPHNLDLIFTLTGGLTAALVLGFITHRLRLSPIVGYLLAGIAVGP
                     FTPGYVAHGGIAEQFAELGVILLMFGVGLHFHLKELLAVRRVALPGAIVQSAAATALGV
                     VVAQFAGWGTAAGVVFGLAISVASTVVLLRVLADYDVLHTPAGHVAVGWLVVEDVFTVL
                     VLVMLPVVTGPEASGDLKGILLSVGAAILKIGVLMAFTLIVGQWVIPRLLGYVAKTRSR
                     ELFTLTVLVLALGIAVGSAKLFGASMALGAFLAGMVVGQSALSSRAASEVLPLRDAFAV
                     LFFVSVGMLFNPAEVGAHLGLVVGTLAVILIGKPVAAFVVVVLLGYPMKKAVTVAVALA
                     QIGEFSFILATLGRSLGVLPEQAMPALVVASVISITLNPMIFRYVEPVSRWLETRWGNK
                     RKDDEPMADIKHADPAHRAVVVGYGPVGRTLTKLLRENEIDPTVIELNHETVHRLNQEG
                     IRAVYGDAAQPEILERAGIKEASSLVFAASGSPADAVILTARSMNPDIQVLARTAFLRE
                     VQALKDAGASVVTVAEAEVALAMTEHLLTQLGATVEQLDRARERVRTDLGSLVGVKVGA
                     "
     misc_feature    11162..11176
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.93"
                     /tool="antismash"
     misc_feature    complement(11168..11188)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.17"
                     /tool="antismash"
     gene            13069..14472
                     /locus_tag="CMC5_RS13670"
                     /old_locus_tag="CMC5_027700"
     CDS             13069..14472
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010685891.1"
                     /locus_tag="CMC5_RS13670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027700"
                     /product="DNA topoisomerase IB"
                     /protein_id="WP_082362465.1"
                     /transl_table=11
                     /translation="MRVDRRHARSFASRGRRSEPRTRKARRGKKALALPPVQVLPVASA
                     EEAGLRYVTDAMSGLRRMRAGRGFYYVGVSGQPVRDKAELARIQALGIPPAWTDVWICP
                     FRDGHLQATGRDARGRKQYRYHVRFREVRDETKYHRLLSFAAALPGIRRRVEEDLARSG
                     LCRERVLATVVRLLEKTLIRVGNDEYARSNESFGLTTLRDEHVEVQGPELRFSFRGKSG
                     RDHAIGVRDARLARIVKRCQDLPGEELFQYVDEAGAQRVIHSGDVNQYLREISGQEFTA
                     KDFRTWAGTVLAAQELSRVGPASTVAQSKRNVVAAIDAVAARLGNTRAVCKRCYVHPLL
                     LEVYAEGKLPVPSTGAATGEGAATAEVRRAVIAVENALPPHEVWVVELLEARLRAAADA
                     PSLEAQLVKSVRVTRVKATRRGSGRSVEKGEGRGRASKGQAVAKSRATAKGRASTKGVS
                     GTSRGTRRP"
     gene            complement(14438..15793)
                     /locus_tag="CMC5_RS13675"
                     /old_locus_tag="CMC5_027710"
     CDS             complement(14438..15793)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS13675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_027710"
                     /product="hypothetical protein"
                     /protein_id="WP_050430831.1"
                     /transl_table=11
                     /translation="MGTAGRLVMIGLPAISITLAAAVMLGPGRVRVVTGITAWGSPSPG
                     GEVLALRLHALQRRLGIDEPAPDLPLTVTARAAGTSLGTWTGPTNQDGIVEASLPAPRG
                     LASPLHVTIAQHERILLDAELPLSPPPALPAPPPPFAGQRSGDIHLELTLAHGALAAPF
                     PAQLRVRALGPDQRPLPDIPIEARATGAVFPLAVDPLITSTDSNGDATIGLNPHAPLFE
                     LTITARKEPLTGTLEATLPVVPGAFWLIPLGDPPRGLRILAPAPRRHAYLSFLGPHGRH
                     AGAIVPLVAARGGFPQGELPIDFPLPSPLWIVVASDPDERGAATLAWPIPVTTPAVPAP
                     PIALLADGMPRVEAHEQQRAAHARRLGLLILVVAAVTEALLTLALARRARRHLTAHLQE
                     ASERGFSEPLPLADQRRLLGATGGIDQTLWVLVLAALTALAFTAVASLATFR"
     gene            15862..16596
                     /locus_tag="CMC5_RS13680"
                     /old_locus_tag="CMC5_027720"
     CDS             15862..16596
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020738985.1"
                     /locus_tag="CMC5_RS13680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027720"
                     /product="hypothetical protein"
                     /protein_id="WP_050430832.1"
                     /transl_table=11
                     /translation="MAADKPTKRKRKSPGTAADVGGAFLRQRSDPRKERRFENSSSVGA
                     VLTMVGGSLAALALGAGVFGQWFRGDGTTPHPYALHLLGAGVAFAIAILLFGQWGSLPV
                     RVGDAGVAVERGTEVERLGWHDVQGVLLGGGALTFRGAGMSIVIPLRSQPEAAARALAE
                     ARTRIPARVKEIDEKALPAPSDAAGQVLSLEPPQIAGLRCKSSDKLISFERDARLCGRC
                     GELYHKDDVPRRCVTCDAPLLG"
     gene            complement(16664..17557)
                     /locus_tag="CMC5_RS13685"
                     /old_locus_tag="CMC5_027730"
     CDS             complement(16664..17557)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020738984.1"
                     /locus_tag="CMC5_RS13685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027730"
                     /product="HD domain-containing protein"
                     /protein_id="WP_082362466.1"
                     /transl_table=11
                     /translation="MEALEYAAVRAERGPENQVVRASTADFKAATTLYLPDVRKMLDRV
                     MMSSDAEAGLDALLECGALAAMLPEVEAMVGFGDGEWRHKDVWKHTKQVVRQAVPRLEV
                     RWAALLHDIGKLKTRSISPNGEVHFFGHAEVGARMFDRIDRRLPLFARDEALKSTVRLL
                     ILHHLRASQYDASWTDSAVRRFTKEMGDLLKDLLDLSRADITTKRPEKKRRGLRQISEL
                     SDRVEKLAVEDAVIPPLPGGIGDAIMSAFCIPPSRRIGELKKALEAAVESGELQPHQPS
                     EFYVNFLREQADRFDL"
     gene            complement(17757..18653)
                     /locus_tag="CMC5_RS13690"
                     /old_locus_tag="CMC5_027740"
     CDS             complement(17757..18653)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020738983.1"
                     /locus_tag="CMC5_RS13690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027740"
                     /product="hypothetical protein"
                     /protein_id="WP_082362467.1"
                     /transl_table=11
                     /translation="MVFPFAHPPYLAQGLGGTRARSTSESSAGRLTRRGGKGTALAPRV
                     SPAAIRLPDPRALPFEIRFPPGYPRIFVHEGARQAMARRLELATRCPVLLSVTDNFREM
                     LSSSREGGVLRARVHHMFLDAPAPVQEALVRYLVDQDREGSLVVGQYIDQNGYRIRACR
                     PVSTPVRTQGKTHDLLQLYQKVNHTYFGGTMDALITWGRRGKAQKPRRTIKLGSYSAVE
                     RLIRIHPALDRPWVPRYFVSYVIYHEMLHHVIPCGQEHGRRILHPPEFLARERMFRHFE
                     RAIAWEKAHVSRLLRAA"
     misc_feature    complement(18732..18746)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.65"
                     /tool="antismash"
     gene            complement(18848..19390)
                     /locus_tag="CMC5_RS13695"
                     /old_locus_tag="CMC5_027750"
     CDS             complement(18848..19390)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020738982.1"
                     /locus_tag="CMC5_RS13695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027750"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_050430834.1"
                     /transl_table=11
                     /translation="MRLYVMRHGPAEDRSATGRDADRALTAEGKGRVQAVALHLQGQRG
                     STSTLRILSSPLRRARETAEIMAGVLQEAERVGASELGPELREELALDADLPQTLRLAS
                     EALGTGVDTLLVGHAPTVDHLLRSLAPGDGQKPPATVAGGFCTAMVVALEPHEAAPRWR
                     MVDMIDPRTFRDTENHR"
     gene            complement(19394..20539)
                     /gene="recA"
                     /locus_tag="CMC5_RS13700"
                     /old_locus_tag="CMC5_027760"
     CDS             complement(19394..20539)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /gene="recA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020738981.1"
                     /locus_tag="CMC5_RS13700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_027760"
                     /product="recombinase RecA"
                     /protein_id="WP_050430835.1"
                     /transl_table=11
                     /translation="MSEEKNSKQKHAALELAIASVEKEYGKGAIMRLKEGQSLHDEVPA
                     ISSGSLSLDIALGIGGYPRGRIVEIYGPESSGKTTLTLHAIANIQKNGGTAAFIDAEHA
                     LDVNYAKKLGVKTDELLISQPDYGEQALEIADMLVRSNAVDVIIVDSVAALVPKAEIEG
                     DMGDSHVGLQARLMSQALRKLTGTVSRSQCLLVFINQIRMKIGVMFGSPETTTGGNALK
                     FYSSVRLDIRRVGQIKEAVAGGKDPAVVGNRTKVKVVKNKMAPPFREVEFDILYGHGIS
                     HSGDVIDLATEASIVEKSGSWYSFQGERIGQGRENARSFLEQHPAMLEKVEQLVLAKHG
                     IHRRPGNGADAAPAAPAPQGKGREAAAPAAEGGKRQTPKAN"
ORIGIN
        1 ctccgcggcg accagaagac ctaccgcttc cgcgtcgcga gcggcggcag cgtcgacgtc
       61 ttcgaggcca tggtcaccgt ccagctcgct cacgcctcga agtcgcccat gtcgaccgcc
      121 gatttccagc gtctccttcg cggcttcgac gcttgcggca agacgtcggg ctgagcaccc
      181 ggcctcgcag cgcgccgtgg tagcttgctc ccgtcatgct ggtcgaatgc aggttctgcg
      241 gtgctcctct cgatgtctcc ggcaccacgc cgctcgtgaa gtgccgttac tgcgagaaga
      301 ccagccagct ccgctccctg cgcacgatgg tcccccggac ccctccgaac tggacgccac
      361 cgccgcagtg gacgccgcct ccccacctgc acttcccgac caccaagccg ctcgcatacc
      421 accatgattt cgtccggatg cagtacgtcg tcgtgctcgg cgtcatgctc ctcgccctgg
      481 tggtcggcct gctgtcgtcc ggaggcacca gcaagaagcg cccgcacagg ggcgtgaagc
      541 gcgagacgat cctcagcacg ccgatgcgtg gcggatgcgt cgtggccgag gcgagtaccc
      601 atgtttctcc ggatgcgaag ggagagattc atgtcgaggt cgacgacgac ctcgtgccac
      661 ggatgacgtt ccagtgctcc ccggagaagg tcgagcccct gcagcgcatc tcgatccacc
      721 tgcgcgacgc ccggaagcac gacgcgcgca tccagacgcg gctccgcgca ctcttcggac
      781 gccggttctt gcagtcctcg ctctcgtggg aaggagcgag tgtgcagtgg ctccccgagc
      841 tgggcttgct gaccgtcgat gtcaaacgga cgctggacga cggcagcgag aaccctcacc
      901 gcgtccagca gatcgaagcc ctctgggggc tcgccaagga gctcgcgttc caggcgcccg
      961 cgacgctcga tccgcagacc gtgcgcgatt acctcggcgg aggctacgcg ctgagcgccc
     1021 tcgccacgct ggatccgaag accccggtcg agcgcagcgt gagcaccttg agtgctcgtt
     1081 tccgcggcct ccacacgagg accctcggcg acctccacgg cttcgtcgag gaggagcagc
     1141 ggctcgccat cgaccacccc tggtttggac tggccacctt gcggtgggat ggccgtccag
     1201 gcagcccctt gaagaccatc agcttgttcc ctcccacgct ccttcagggg gtgtacgtcc
     1261 agcggggcgc catcgactgc ctgacccgcc tgctcggccc accggaggca cccagcagcc
     1321 gcaagtcgtt ctcgggtcag ggagctgtct tcacctggcc gggcgaggga aactacagcg
     1381 tggcggcgct ggagacgtcg ttggtgatcg acgcgcgcgc agcctccagc gccgggttcc
     1441 agcgcatcct gaatggcttg agcgcctgcg gccagcctgt gcgctgagcc ctacttcgcc
     1501 caccctccag cccctcgcgc ccaccctcca gcccctcgcg cccacctcgt cgccaacgcc
     1561 cagcgcggga tgctctcccc gcgcagagca ttgaccgctc gtgtccgcgc ctgcactgtg
     1621 gagatccacg gaccgggggg cgcagcgtgg aacagcaagc cgttaccgat cgaattccta
     1681 cggaatttcg ctactgggac aacctctcga cgccgaaggc gcagcggtta cgaggcatcc
     1741 tcggcgcgct cttcggggtc gaccccaagc tcaccgacga gacggtgcgt acctacgccc
     1801 gctcgtacta cgacgccgat cccctcgccg agtccgtcgt cgacgaggtg tacctcccgc
     1861 gcggccaggc cgccggccgg cgcctcttcg accaggccct cgcctgcggt gtcgacgcca
     1921 tcccggacgc gcccccctcg ctccggcgcc tcttcgagga cctggagact ccacccccct
     1981 ggctggacga gcagcgcgtc gcgctgggcg cccgcgtctt ccgtcgctat ggcacccacc
     2041 tctactcgtt cgctggcgcc atcaccctcg aaggctaccg agagagttcg gtcgccaagc
     2101 cgctcgtgct caccggcgcc tacaccggca gctccgccaa ccgccgcttc ctggagaccg
     2161 ccgccttctg gaccgacgtc tccgagcctg gcggcctcga tcctggatgc cgcggccgcg
     2221 agacggccct ccacgtgcgc atgatgcacg tcttcgtccg caagcgcctc ctcgcccatc
     2281 cccagtggca gctcggggcc tggggcgtcc ccatcagcca cggcgacgcc ctcctgaccc
     2341 tcctcggcgg cagcttcgtg cccggctacg ccctcaagct gctcggctac cgcacctcgc
     2401 gcgaggagat cgaggcgatg atgcacttct ggcgctacgt cggccacctc atgggcgtgc
     2461 agccccggtg gttccccgag accgtcgagc aggccttggg cctgctgttc acctcgatga
     2521 tcaagggcgc ccagcgctcc ggggacgacg gcgtgctcct cgcccgctcc tacctcgcct
     2581 cgtacgcgcc caccgccgcc gaccgctggt tcaccgcctg gagaaagcgc tgggagcaca
     2641 agctccagct cggctacgtc agcttcttcc tcccgccccc cagctacgcc ctctacggcc
     2701 tcccgcgccc cggcctctgg cgcttccacc ccttgctcca ggcccccttc gtcttcgccc
     2761 gcgagactgc gcgccagcac ctccctcgcc tggacgactg gctcgacgag cgcgcgcgcc
     2821 gcgagacccg cgactgggtc gacgcgcgcc tcggcccccg ccgcgccgag taccgcgccg
     2881 ccgagccaat ccggccgtga gccgagctgc tccggccggc gttcggtcgc gtggcgggac
     2941 gatcagccgc ccagcagcac agcgtccggg accagcatgc aggtccaccg cgcctcaccg
     3001 tggaggtggc tcagcatgct cattccatcg gtcacccggc tcgggacgac gaggtggacg
     3061 tcgacgctgg cgacgtcgca gctgttcatc agcttgtgca atggcagcgt cacctgctgc
     3121 accgtgtcga cggcggtcat cccgctcgtg agcagcgagg gcaggtgcgc atggccacga
     3181 tagaagcgga gcgtgtaggg gacgggtctc gtggggtgcg cggcggtgaa ccggagggtc
     3241 accgtatcgc cctgcttgtc gtggtagccc acgcagccgc agtgggtctg cgccgccgtg
     3301 ccattgagca gcatcccctc gaacccggcg tcgcaccgcg cattgtcgat gcgcaggcgc
     3361 cgcgaggccg cggcgaatgc aacgccacgc tcgtcgaaca gctcgacgcg cagcgtggcc
     3421 attccattcg gcacccgcgt cgagtcgatc ctcgcggcga gggacaggct ctgccagcca
     3481 tcctcctccc tgcgcagggc gtggaggtgc gactgcccgc cgacgcagtg gaccgggatg
     3541 tccgtcgcca cccagctcgc ggtcgcgtcg cgcttgagct cggggctacc gtcgtgcctc
     3601 accagggccg cgccctcggc gagggacacg cggtagtaat gggcaccggc ctgccgcgcc
     3661 cggaggtgat cgagcgtgac gaccagcgtg cccccgaagg cgacgttctc gaccttgaac
     3721 ggagcgccca tcaggtgcga cgtgtccgcc tttccctcgt gctctccgct cgggacgacg
     3781 cattgaaatg ggacgagccc gatgccgaag ccaaagtcgg cggggggggc ggtctcgagg
     3841 cggccaatgc cctcctggct ggcgacgaac cactgacctg gtgtgagttc ctcggcgctc
     3901 caggggtcct gggtcgcgcc gtccatgagc acctcggcgt gaggctcgtc cccggtcaac
     3961 ccgctcacgc ggaggagctg gttcgcaggg ctgcgccgcg tgagcaggag gctcgctcga
     4021 cgcgggtctg cccagcgcag gaagcccacg tcccccaggc cttccaggag gaccgcgcgc
     4081 cggcctcccg tgatgcgcag caagcgcccg ccctggcctt gctcggcgac atagaaggtc
     4141 tcgccgtccg ccgcgacgag cagcccgacc ccctgcgcaa tgcctgcatg aatgcggctc
     4201 ggcgagcgcc gctggcgcgg atcgatctgc cagatgcccg cgtcgtccac cacgtagagc
     4261 agatccccgt gcgcggcgat ctggtgcggg ctgctcatgc cgtcgaagag cacgtgggca
     4321 cctggcgggg cctgcgcatc gaaaggaatg tagagcagcg ccccgctgtc gagcgtcacc
     4381 ccgtggtgcc cgtcgtgctg cgtcagcgcg cgaggaccag gtagccccga caggacatcc
     4441 atcggctcgc ggtggagctg ataggtcacc cagtccgcct tcgtgaggcc gtcgacgaga
     4501 tccttgtaga tccggacgat ggcgtggtgc ccgaggcgca cggtcttcac cgcgtagtac
     4561 cgccctcgct ccgattgccc gtcctcggtg agcggcgccg agctgtagct gcacgtccgc
     4621 agcttctccg ggtcgacgtg ggcgaggtcg ggcggtggct cctcgagttc gcagagcagc
     4681 gcgccgttca gccgggtgat gctcccaccc gcgcggcgga ggctcgcgga cccctcgtcg
     4741 agccggaggg tcgtgcccac ggtgaacgcc gcgccagcgc cttcggagac gatggcgtgc
     4801 ggagggacga ggaccttctt gatcctcccc gcgccagcgc cgtcggtttg caggaaatag
     4861 agatagtcgt cgctggaagc atggaatgtc ccgcgcgcgc ccgataacgg cggcgcgaac
     4921 tgcgtgtacg ccatggtggt ccccccccga gtccgctgaa gtcgacaggc tctcgatgcg
     4981 ccgatggttc tggatccatg ccgcgagcgc ctgggggcgc acacgacggc gctgtgccgt
     5041 cacgtcatgg ccacgatgcc tcccctcatc gtgaacgctt cagtgtaggt cgtgcaggcg
     5101 gttgctcaat gtcgagggaa tcggagtcga cccgattgtt cggccatcga ggacggtggg
     5161 gcaggtgagc tgggtgaggc catggtcttc ctggacccgc cgcggagcct gaaggaggcg
     5221 aaactgggtg cgtcagcggc cgacggtcgc ggtgccggag cgaaacgagg ggggcggcgg
     5281 ccgacgaccg gggtgctgga gcgaaactgg ggccgtcggc gggacagggg aagtttcgct
     5341 cgtcaactgg gtcggtcggc gggcgacgcc cccagtctcg ctccggaact gtcggtcgca
     5401 acgggggacg acgccccccg tggagaggtg aaactcccct cgtcgggggg tgatggtcgg
     5461 cgttgtgtcg gggaactcac cccgtcggcg tcgcccaggg gagtttcctg gcgaaactgg
     5521 gtgcgtcggc gttgccaggt cgggttgcac ggtgaaactg ggtgcgtcgg cggccgtcgg
     5581 gcgcaggagg agaggtgaaa acgccatcgt cgacggaatg tcagtggccg tctccgagcg
     5641 aaactcacga cgtcggcgag cgatgcacgc gtgcgaaggg gctgaccgcc agcggttggc
     5701 acgcggggtg atgaacgggg gcggttggta cgggagtgaa agacggaggg ctgctggcag
     5761 agcggtgggt gagccggtgg gtgagtgtgc tggtgtgagt cgctacccgg gaggtgggga
     5821 ggagggggac gagcggctcg acccgtcgcg ctgggcggtg gcgcgctcgc ggtacttgcc
     5881 cggggggatg ccgcaccagc gcttgaaggc gcgggtgaag gtgctcacgt cggagaagcc
     5941 gaggaggaag gcgacgtcgg ggatcgcgat cttgccttcg cggaggagct gctcggcgct
     6001 ctcgcggcgg acctcgtcga gcaggtcgcg gaagctcacg ccttcggcgg cgaggtggcg
     6061 gcggaggctg cgctcgctgg taccgaggcg gcgggcgatg gtgtccgtgg tgggctcgcc
     6121 ggcgttcatc tccagggcga tggcgtcgcg gacgcgatcg gggagggcgg tcgcggcgcg
     6181 ggtccgacgg cgcagctctt cggcgtggtt cacgaagaag gcggagaggg cggcgtcggc
     6241 gccgcgcggg gtcttggcga ggagcgcgcg gtcgaacgag aagctgtccg tgggggcgcc
     6301 gaactcgatg gtggtgccga agaagcgctc gtgcgcggag acgtcccgag gggcagggtg
     6361 ccggaaggtg acccgggtgg gggtgaggct gggagtggac gactcgcgaa agcagtggag
     6421 gcaagagcag agggagagct cggcggcgag gcgctctccg aggctgaagg tggaggccgc
     6481 cgtggcgtgg atggtggctt cgttggggcc gctgggatcg tcgagctgcc agctcgcgtt
     6541 gtcggagagc agcacggcgt agcgggtgag gcgttcgagg gcttcacggc cgctcttgct
     6601 ggtggcgatg acgaagccca tcacgtgcag ttcttcgagc cgcatcccct gcgcgacgtg
     6661 gacggggagg ccagggtcgt cgaacgtgcg cgcgaggtag gcgagcagat cggcgtaggc
     6721 ctggagggga atgcggcgct cgatggactt gagttcgtcg ggccggaggt ggacgcgctc
     6781 gcagaggacc cgtggctcga tgcctcgcgc tgcggcgtag cggacgagct tgccgacgtg
     6841 gatcgccgac gtggtgagcg agggccggcg cacgctcatg gtcgcgccac gctaccacgc
     6901 acggccggga gggacctcgg gcggagcgag ggagcacgat gtcgaccctc cgtagatgca
     6961 ggaatccggg gacgcaggaa aagagaaggt cgcgccccga ggtgcgcggt gtgcgcaggc
     7021 cgccgcttat ttcgtgagca ccgagccgta ggagatcgtg gccttggcgg tctgcgcctt
     7081 cacggtctcc caggggacgg ggatctggtc ggcgccgagt tcccagctcg tgacgaggcc
     7141 ggccgacgtg acggtgttgg cctcgctcat cgcggcgatg tgggcgtcgg tgacgacgaa
     7201 ggccatcatg gactcttcgt ccttccagac gctgatggtg cgtccgtagc cgcacgactg
     7261 ggagagggcg agctggtagc cgatgaggcc cggctggtcg gcgagctggt tggtgagcgg
     7321 cgtcatcagc ccgaagaagc ggttcatctg gtcggcaggg atcgagacca gggtgctgct
     7381 ggcgatgtag cgctcctgcg ggggctccgt gaagccgccg ttcgtcgggt cgtagccggg
     7441 gccggcgaag gcaccgggga agatcatgtc gctgtcgtcg cacggaaaga tggccgcgcc
     7501 ggtgaggtcg ggctcgggct cgggttgccc gccggtcgtc ttgccctgac cgtcgtcgct
     7561 ggagctgcag gcagtgaggg cacagaggcc gagcgagagg gcgacgagcg ggagtgcgtg
     7621 gcggatggtg cggtgcatgc gggtcctcgg gggtgttggg tctgcggtgc ggaacatcgc
     7681 ggcgatgcga tcagtcgcgg cgcgagacga tcccgaagag cagctcgggg aacgtgcgct
     7741 ggaggcggtt ggatcgaaaa tcggtgcgtc ggcccatgct gcggagcttc acgggcgtgc
     7801 cggtgggatg gccggcgccg agggagacga tccagacgag gtcgccgtcg tcacggcgga
     7861 cggcgtggta gacgtacgag ccggtggtga tgcgctcctc gacgcggccg gtgctcggcg
     7921 cgccgtcggc aggggtgcgc tcgagggcgc cgaggggatt ggcaccgtca ggcgatgggc
     7981 tgctcagcga tgcccgcgct ggcgcgtcag gcgatgggct gctcagcgat gcccgcgctg
     8041 gcgcgtcagg cgatgtgccg tccggtgcga ggggcgcctc gcgcggtgcc gaggggggcg
     8101 tggtggcgct gggatcggcg ctggcgaagg gggtcggctg gaggctgacg agcgcggcga
     8161 gagaggccgc ggcagcagcg agcccgagca gcagtcgctc gtggcgcggt gagcggggtc
     8221 gcttcatacg ccgggaaacc taggccgtac gcgcggcctg aaccttcacc ggagcggcca
     8281 agctctttgc agttccggcc acgccgaggg ggtcgatcgg tcgccgtgtg cggcgtgggg
     8341 cgcagggggt gcgcttggga ggggtcgggt cttggggtaa cctgattctc atggcctctc
     8401 ctgccctcgc tctgtcgatc gtcctggatc agcgcggtct tctcccggcg acgcccgtgc
     8461 aggcacacct cgtcgcagag ctgcgcgcgc tggggggcgg ggtggagcgc gcgaggccgc
     8521 cgctgtcggt gatcttcgcg atcgacgtgt cgggctcgat ggtcgggccg ccgctggagc
     8581 acgccgcgcg gtcgatcgag cggctggtgg agctgctgga gcccaccgat cgggtggggg
     8641 tggcggcgtt ctcggacgag gcgagcgagg tcgtgccggt cgcgcggctc gacgcggagg
     8701 cgaggcggtc gatcagcggg caggtgcaca agctcgaagc gggcggcggg acgaacgtgg
     8761 aggcgggcct gtcgctggcg cggtcgatga tgccgccccg aggcgtccac gagcggcagc
     8821 tcatcctgtt gctgagcgat ggcgccccga accgggggag ggtggccgtg gaggagctgg
     8881 ctgcggtgac gcgcgggttc cggcccgagg tggtggtctc gacgctcggc tacggggcgc
     8941 atcaccacga ggacgtgctg gcgcggatcg cggacgcggg cgcggggcgc taccacttca
     9001 tcgcggatcc ggcggtgtgc tcggtcgagc tggcgcaggc gctcggggtg caaggggacg
     9061 tggccgcgga ggcgatcgag ctgtcgctgt cgccgggaga aggggtggag ctgtcgcggt
     9121 tccacgggag ccgggagctg cggttcgggg cgagtggggt gcgggtcgcg gtgccggatc
     9181 tgctgcacgg ggggagggcg gtgacggtgg ccgagctgtc gctcacgccg ccgcgggagg
     9241 cgggggtctg gaagccgctg ctggcgacgg tgacgttccg gcgcgcaggg gagcgggaga
     9301 cgcagacgat cgcggcgacg ctggaggtgc ccgtgggggt gacggtgacg gggccgaacc
     9361 cggaggcgcg ggccgaggtg ctgatcgcgc aggcggacga ggcgcgggtc gaggcgcggc
     9421 gtcaagcgga ccggggtcag ttcgagggag cggcggcggt gctgcggggg atgatcggca
     9481 ccatcgaggc ggagccgggg cggggacgcg gggatggctc tgcgctcgac gaggcgctgg
     9541 agcagctcgt ggacgaggcg gtggcgatgg agcgcaagcc gagccgcgag gcgtactgcg
     9601 cgttccggaa ggcgcaggtg cagagccggt cgctggccga gggggccgag tcgtacgcgt
     9661 cgtcgccgat gagcgcgagg atggtggaga gcgtggccgg ggcgctcccc agggcgtcgc
     9721 tggtggtggt cgagggcgat gagccgggca agcggttccc cctttcgcag ccgcgcaaca
     9781 ccatcggtcg gacgcaggcg gcgcaggtgc ggatcgtcga cgtgaacgtg tcacggatgc
     9841 acgcgatgat cgtggggcaa gaggggaagt tcttcgtgtc cgatctgggg agcacgaacg
     9901 cgacgtggct gaacggggag gtgctggaga agcccgtgcc gctcggccct ggcgacgtgc
     9961 tgcggatcgg tgacgtggag ctgcggtacg aggaaggcgc tcagtcgtcc ttgtagcgag
    10021 cggcacgctc ggaccagtcg ccgttcgcgc gcatccacga gcgcaggccg gcggtgaggc
    10081 gggcgaggtg cgaggccacg ggctcctcga aggccgtgag gctgcgttcg agggagaggt
    10141 aggtggcgag ctcggcgtcg tgcagcgcgg cggcgcggtg gagggcgtcg ttcagggagc
    10201 agcgctgctc gtgctggatg aggatcacca ggttgttcac gtcgccgtgg cggatctcct
    10261 tgcccaggga gaggatgtcg ttggagtaac agatgacccg gttggccgcg agctgagtgg
    10321 cctgcacgag ggggtgcgcg tggagccgct ccggcaggtc gacctggttg gtgaggtaga
    10381 tgaggtcgaa gcaggggatg acggcgccgg tgaacgggcg catggccacg tactcggcaa
    10441 cgcaggggac gttgtgtcgg cggcggttct cgcactccca gcggttggcc tcgaagtagg
    10501 cgctgacgtc acggcagaag cgctcgagca gcggcgcgga ggcgagcttc gcgaggcgga
    10561 cgaggatgtc ctccagggcg tggacgagcg ggacgtcgtc gggccgagcg tgcgctccgc
    10621 cgaggatgct gtcgaagcgc gtgtgcaggt gcgccacctg ggtggtctcg cgtccgagca
    10681 gggtctcgtc gagctggtcg tctgcgagga agagccacgc gagaaagcaa gaggcgagat
    10741 cgagctgctc ctcggaagcc gtgggataga tgcgcccacc gaaccaccca tactcctcgt
    10801 ggcgtcgctg tgcggccggc tcggtgggca tgatgccgac ccggtgcgtc caatcgatgg
    10861 tggctcgatt gatcggctca gcgagcgggt ggagcgcagg agggaaggga tagctcaaca
    10921 ggggccggcc gttggtttcc atgggttgac tgcatgagca gttatcccag gtatttccct
    10981 cgaaaaggcg agatctcgac gccgcgaacg tcgttgtttc gacgagatgt gtaggcgcca
    11041 accgaaacgg gtcgagccgc tgtcctcggc ggatgacagt gtcaccccaa aagagtgttt
    11101 ggcccgtccg cccgcggaag gtagaccatt caaccggtag agcgaacgat gccgcacaac
    11161 ctggatctca tcttcacgct gacgggaggg ctcaccgccg ctctggtgct gggcttcatc
    11221 acccaccgac ttcggctctc gccgatcgtg ggatacctgc tcgccgggat cgcggtgggc
    11281 cccttcacgc cggggtacgt ggcccacggt ggaatcgccg agcagtttgc ggagctgggg
    11341 gtgatcctgc tcatgtttgg cgtggggctg cacttccacc tgaaggagct cctggccgtg
    11401 cgtcgggtgg ccctcccggg tgcgatcgtg cagagcgccg cagcgacggc actcggggtg
    11461 gtggtggcgc agttcgctgg ctggggtacg gcggcgggtg tggtgttcgg tcttgccatc
    11521 tcggtggcga gcaccgtcgt cttgctgcgc gtgctggcgg actacgacgt gctccacacg
    11581 ccagccgggc acgtggccgt cggctggctg gtcgtcgagg atgtgttcac cgtgctcgtg
    11641 ctggtgatgc tgcccgtcgt caccggcccc gaggcgagcg gcgatctgaa ggggatcttg
    11701 ctctccgtgg gggcggcgat cctgaagatc ggcgtgctca tggccttcac gctgatcgtg
    11761 gggcagtggg tgatcccgcg tctgctcggg tacgtggcga agacgcgttc gcgcgagctg
    11821 ttcacgctca cggtgctggt gctggcgctc ggcatcgccg tcggatcggc gaagctgttc
    11881 ggcgcgtcga tggcactcgg tgcgttcctc gcggggatgg tggtcggcca gtcggcgctc
    11941 agctccaggg cggcgtcgga ggtgctgccg ctgcgtgacg cgttcgcggt gctgttcttc
    12001 gtgtcggtcg gcatgctgtt caacccggca gaggtggggg ctcacctcgg cctcgtcgtt
    12061 ggcacgctgg cggtgatcct gatcggcaag ccggtggccg cgttcgtggt ggtggtgctg
    12121 ctcggctacc ccatgaagaa ggcggtcacg gtcgccgtcg cgctggcgca gatcggtgag
    12181 ttctccttca tcctggccac gctcggtcgc agcctgggcg tgctgcccga gcaggcgatg
    12241 ccggcgctcg tggtggcgtc cgtgatctcc atcacgctga acccgatgat cttccggtac
    12301 gtcgagccgg tctcgcgctg gctggagaca cgctggggga acaagcggaa ggacgatgag
    12361 ccgatggccg acatcaagca cgcagacccg gcgcaccggg cggtggtcgt cggctacggt
    12421 ccggtgggcc gcacgctgac caagctgctg cgcgagaacg agatcgatcc cacggtgatc
    12481 gagctgaacc acgagacggt ccaccggctg aaccaggagg ggatccgtgc agtctacggc
    12541 gacgcggcgc agccggagat cctggagcgc gctggcatca aggaggcgtc gagcctcgtg
    12601 ttcgccgcgt cgggctcacc ggccgatgcg gtgatcctga cggcgcgctc gatgaacccg
    12661 gacatccagg tgctcgcgcg gacggcgttc ctgcgcgagg tacaggcgct gaaggatgcc
    12721 ggggcgtcgg tggtcaccgt cgcggaggcg gaggtggcgc tggcgatgac ggagcacctg
    12781 ctcacccagc tcggcgcgac ggtggagcag ctcgatcggg cgcgtgagcg cgtgcgcacc
    12841 gatctggggt cgctggtggg cgtgaaggtc ggcgcctgat cgcggtctgc ggtgaggggg
    12901 ggccacgcgc gtcggggggc gcgcggtggg gggacgcgcg gcgggcaggg ggaatgaccg
    12961 gctgaacggg cgctgcccgg gggggcgacc cggggcgcag cggcagcgca ggctgtgccg
    13021 gctgcgagca gctccgcgcg gcgcgaggct tgcctcagcc ggtggtcgat gagggtcgac
    13081 cgccgtcacg cccgttcttt cgcctcgcgg gggcgcaggt ccgagccgcg cacccggaag
    13141 gcgcggcgcg gcaagaaggc gctggcgctg ccgcctgtgc aggtgctgcc cgtggcctcg
    13201 gcagaggagg ccgggctccg ctacgtgacc gacgccatgt ccgggctccg gcggatgcgg
    13261 gcaggccggg gcttctacta cgtgggggtg agcggtcagc cggtgcggga caaggcggag
    13321 ctggccagga tccaggcgct ggggatcccg cccgcatgga ccgatgtctg gatctgtccc
    13381 ttcagggacg ggcacctcca ggcgacgggc cgcgatgcgc gggggcgcaa gcagtaccgc
    13441 taccacgtgc gcttccgtga ggtgcgggac gagacgaagt accaccggct gctgtcgttc
    13501 gcggcggcgt tgccggggat ccggcggcgg gtggaggagg atctggcgcg gtcggggctg
    13561 tgccgtgagc gggtgctcgc gacggtggtg cggttgctgg agaagacgct gatccgggtg
    13621 gggaacgatg agtacgcgcg gagcaacgag tcgttcgggt tgacgacgtt gcgggacgag
    13681 cacgtggagg tgcaagggcc agagctgcgg ttctcgttcc gggggaagtc ggggcgcgat
    13741 catgcgatcg gggtgcgcga cgcgcggctg gcgaggatcg tgaagcgctg ccaggacctg
    13801 cccggggaag agctgttcca gtacgtcgac gaggctggag cccagcgcgt gatccactcg
    13861 ggggacgtga accagtacct gcgggagatc tcggggcagg agttcacggc gaaggatttc
    13921 cggacctggg cggggacggt gctggctgct caggagctgt cccgggtggg gccagcgtcg
    13981 acggtggcgc agagcaagcg gaacgtggtg gcagcgatcg acgcggtggc ggcgcggctg
    14041 ggcaacacgc gggcggtgtg caagcgctgc tatgtgcacc cgctgctgct ggaggtgtac
    14101 gcggaaggaa agctgccggt gccgtcgacg ggcgccgcaa cgggggaagg ggcggcgacg
    14161 gcagaggtgc gtcgggcggt gatcgcagtg gagaacgcgc tgccacctca cgaggtgtgg
    14221 gtggtggagc tgctggaggc gcggttgcgt gcggcggcgg atgcgccgtc gctggaggcg
    14281 cagctcgtga agagtgtgcg ggtgacgcgg gtgaaggcga cgcgaagggg gtcggggagg
    14341 tcggtggaga agggggaggg aaggggacgg gcgtcgaagg ggcaggcggt cgcgaagtcg
    14401 cgagcgacgg cgaagggacg ggcgtcgacg aaaggcgtca gcggaacgtc gcgagggacg
    14461 cgacggccgt gaaggcgagc gcggtgagcg ctgccaggac gaggacccag agggtctggt
    14521 cgatgccgcc ggtcgcgccg aggagccggc gctgatccgc gagggggagg ggctcggaga
    14581 agcctcgctc gctggcttcc tggaggtgcg cagtgaggtg gcgtcgagcg cggcgcgcga
    14641 gggcgagcgt gagaagcgct tcggtgacgg ctgccaccac gaggatgagc aggccgaggc
    14701 gtcgggcgtg ggcggcgcgc tgctgttcgt gggcttcgac gcggggcatg ccgtccgcga
    14761 gcagggcgat ggggggcgca ggaacggccg gggtggtcac ggggatcggc caggcgaggg
    14821 tggcagcgcc gcgctcgtcg ggatcgctgg cgacgacgat ccagaggggg ctgggcaagg
    14881 ggaaatcgat ggggagctcg ccttgaggga aaccgccgcg ggcggcgacg agggggacga
    14941 tggcgccagc gtggcggccg tgggggccga ggaaagagag gtaggcgtgg cggcgagggg
    15001 ccggcgcgag gatgcggagg cctcgagggg ggtcgccgag ggggatgagc cagaaggcgc
    15061 cagggacgac ggggagggtg gcttccaagg tgccggtgag gggctccttg cgggcggtga
    15121 tcgtgagctc gaacaggggg gcgtgggggt tgaggccgat ggtggcgtcg ccgttgctgt
    15181 cggtgctggt gatcagtggg tcgacggcga gggggaagac ggcgccggtg gcgcgggctt
    15241 cgatggggat gtcagggagg gggcgctgat cggggccgag ggcgcggacg cggagctgtg
    15301 cggggaacgg ggccgcgagc gcgccgtgag cgagggtgag ttcgaggtgg atgtcgccgc
    15361 tccgctggcc ggcgaaggga gggggaggag cagggagcgc ggggggagga gagaggggaa
    15421 gctccgcgtc gaggaggatg cgttcgtgct gggcgatggt gacgtggagc ggggaagcga
    15481 gtccgcgggg cgcagggagt gaggcttcga cgatgccgtc ctggttcgtg gggccggtcc
    15541 aggtgccgag ggaggtgccg gcggcgcgcg cggtcacggt gaggggcagg tcgggtgctg
    15601 gctcgtcgat gccgaggcga cgctggaggg cgtgaaggcg cagggcgagg acttcgcctc
    15661 ccggggaagg ggagccccag gcggtgatgc ccgtgacgac gcggacgcgc ccggggccga
    15721 gcatgacggc cgcggcgagc gtgatggaga tggcagggag gccgatcatc accaggcgtc
    15781 cagcggtgcc catgccgaga gcatagccgg tgctggtcga tgcctttgcg ttccggcgct
    15841 gcctccgata ggaagccgag catggcagcc gacaagccga ccaagcgcaa gcgcaagagc
    15901 cccgggaccg ccgccgacgt cggaggggcg ttccttcggc agcgcagcga tcctcgcaag
    15961 gagcggcgct tcgagaactc gtcgtcggtg ggggcggtgc tgacgatggt cggcggttcg
    16021 ctcgccgcgc tggcgctcgg cgccggggtg ttcgggcagt ggttccgagg tgatgggacg
    16081 acgcctcatc cctatgcgct ccacctgctg ggggcgggtg tggcgttcgc catcgcgatc
    16141 ttgctgttcg gtcagtgggg ttcgctgccc gtccgtgtcg gtgacgctgg cgtggcggtg
    16201 gagcgcggca ccgaggtgga gaggctgggc tggcacgatg tccagggagt tctcctcggc
    16261 ggtggtgcgc tgacgttccg gggggcgggc atgagcatcg tcatcccgct gcgctctcag
    16321 ccggaagcag cggcgcgggc gctggccgag gcgcgcacgc gcatcccggc gcgggtgaag
    16381 gagatcgacg agaaggcgct accggcgccc agcgacgcag ccggtcaggt gctctccctc
    16441 gagcctccgc agatcgcagg gctgcgctgc aagtcgagcg acaaactgat ctccttcgag
    16501 cgggacgcgc gcctgtgcgg tcgctgcgga gagctttacc acaaggatga cgtgcctcgg
    16561 cgctgtgtga cctgcgacgc gccgctgctc ggctgaacgt tccagtcgtg ggggtaggga
    16621 gctgaggcga cgcgggcggg ggcgcgtgcc cctgccgcgg gactcacaga tcgaagcgat
    16681 cggcctgctc gcgcaggaag ttcacgtaga actccgaagg ctggtggggc tggagctcgc
    16741 cagactccac cgccgcttcg agcgccttct tgagctcccc gatgcggcgg gaggggggaa
    16801 tgcagaacgc ggacatgatc gcgtcgccga tgccgcccgg gagcggaggg atgaccgcgt
    16861 cctcgacggc cagcttctcc acgcgatcgg aaagctcgct gatctgccgc aggccccggc
    16921 gcttcttctc ggggcgcttg gtggtgatgt cggcgcggga gagatcgagg aggtccttga
    16981 gcaggtctcc catctccttg gtgaagcggc ggacggcact gtcggtccac gaggcgtcgt
    17041 actggctcgc gcgcaggtgg tgcaggatga gcagccggac ggtgctcttg agggcttcgt
    17101 cgcgcgcgaa gagggggagg cgccggtcga tccggtcgaa catgcgcgcg ccgacctcgg
    17161 cgtgtccgaa gaagtggacc tcgccgtttg gcgagatgct cctggtcttg agcttgccga
    17221 tgtcgtggag cagcgcggcc cagcggacct cgaggcgagg gacggcctga cgcacgactt
    17281 gcttcgtgtg cttccagacg tccttgtggc gccactcccc gtcaccgaag ccgaccatgg
    17341 cctcgacctc ggggagcatg gcggcgaggg cgccgcactc gaggagggcg tcgaggcccg
    17401 cctcggcgtc ggacgacatc atcacccggt cgagcatctt ccggacgtcg gggagataga
    17461 gcgtggtcgc ggccttgaaa tcggccgtgg acgcccggac gacctggttc tcgggccctc
    17521 gctcggcgcg caccgccgcg tactcgaggg cttccatggc ccgcgcgggg cttgcttcgt
    17581 tcttgggaag gtcctgcact gcagccctcg cgtcgctcgc gggtggtggt tcttgcccga
    17641 gggagaccgg ctgtttaatc gttccccagc gggaatcaac cctggtccgc gcgggcgagc
    17701 ggggtgggcc cgaggcgctg accgacgcgg ggccgaggag tttgcggggc ggcgcgtcag
    17761 gcggcgcgga gcaagcggct cacgtgcgct ttctcccagg cgatggcccg ctcgaagtgg
    17821 cggaacatgc gctcgcgggc gaggaactcc ggggggtgca agatccgccg gccgtgctcc
    17881 tgcccgcagg ggatcacgtg gtgcagcatc tcgtggtaga tgacgtacga cacgaagtac
    17941 cgcgggaccc agggccgatc gagcgccggg tggatgcgga tcaagcgctc cacggcggag
    18001 tagctcccca gcttgatggt gcgccgcggc ttctgggctt tccctcggcg accccacgtg
    18061 atgagggcgt ccatggtccc gccgaagtag gtgtggttga ccttctggta gagctgcaag
    18121 aggtcgtgcg tcttgccctg ggtgcgtacc ggcgtgctca ccggccgaca ggcgcggatg
    18181 cggtagccgt tctggtcgat gtactgaccg acgaccagcg acccttcccg atcctgatcg
    18241 acgaggtagc ggacgagtgc ctcctgcacg ggggcggggg cgtccaggaa catgtggtgg
    18301 acgcgcgcgc ggaggacacc accttctcgc gaggacgaga gcatctcccg gaagttgtcg
    18361 gtgaccgaga ggaggaccgg gcagcgggtg gccagctcga gccgccgcgc catcgcctgc
    18421 cgggccccct cgtgaacgaa aattcgcgga tagccgggcg ggaagcggat ctcgaacggg
    18481 agcgctcgag ggtcggggag ccggatcgca gcgggtgaga cgcggggcgc aagcgccgtg
    18541 cctttgccgc cgcgccgcgt cagccggcca gcggaggact cggacgtcga acgagccctg
    18601 gtgccaccca gcccctgagc aagatagggg gggtgagcga agggaaagac catctgtccc
    18661 gtcatcctca gcctccggat cgggcgtatt cccggggggg atccttgtca atgcgcgggt
    18721 ccaacgccat gaaatgattc aaaattattg ctggctgggc ccgacggcgc gccgggccga
    18781 ggcgccgcgg agcggagaca cggagtgggc ggcgccattt ctgtatttgt tgtctgattt
    18841 ccggcggtta ccgatggttc tcggtgtccc ggaacgtccg cgggtcgatc atgtcgacca
    18901 tccgccagcg cggtgcagct tcatgaggtt ccagggcgac gaccatggcg gtgcagaagc
    18961 cgcccgcgac ggtggccggt ggcttctggc cgtcacccgg ggcgaggctg cggaggagat
    19021 ggtcgacggt cggcgcgtgt ccgacgagca gcgtgtccac gccagtgccg agggcctccg
    19081 aggcgaggcg cagcgtctgc ggtaggtcgg catcgagcgc cagctcttcg cgaagctcgg
    19141 ggccgagctc ggaggcgccg actcgctcgg cctcttgaag gactccagcc atgatctcgg
    19201 ccgtctcacg ggcgcggcgg agggggctgg agaggatgcg cagggtggac gtgcttcccc
    19261 gctgaccttg cagatggagg gcgaccgcct ggacccggcc tttgccctcg gcggtcagcg
    19321 cccggtcggc gtcacggccc gtcgcggacc gatcctccgc cggaccgtgg cgcatcacgt
    19381 agagccgcat gacctagttg gccttggggg tctggcgctt tcccccctcg gcagcagggg
    19441 ccgccgcttc acgacctttc ccctggggag ccggtgcggc cggtgcagca tcggcgccgt
    19501 tcccggggcg acggtggatg ccatgcttgg ccagcacgag ctgctcgacc ttctccagca
    19561 tggccggatg ctgctccagg aaggagcggg cgttctctcg gccctgtccg atgcgctctc
    19621 cctggaacga gtaccaggag ccgctcttct ccacgatgct cgcctcggtg gccaggtcga
    19681 tgacgtcgcc gctgtggctg atcccgtgac cgtagaggat gtcgaactcc acctcccgga
    19741 aggggggggc catcttgttc ttcaccacct tcaccttggt ccggttaccg accacggccg
    19801 ggtccttgcc gcccgccacg gcctccttga tctggccgac gcggcggatg tcgaggcgca
    19861 ccgaggagta gaacttgagg gcgttgccgc cggtcgtggt ctcggggctg ccgaacatga
    19921 cgccgatctt catgcggatc tggttgatga agaccaggag gcactgggac cgggagacgg
    19981 tgccggtgag cttgcggagc gcctggctca tcaggcgggc ctgcaggccg acgtggctgt
    20041 cgcccatgtc gccttcgatc tcggccttgg gaacgagggc ggccacggag tcgacgatga
    20101 tgacgtcgac ggcgttggac cggaccagca tgtcggcgat ctccagcgcc tgctcgccgt
    20161 aatcgggctg ggagatgagc agctcgtccg tcttcacccc gagctttttc gcgtagttga
    20221 cgtcgagcgc gtgctcggcg tcgatgaagg ctgccgtgcc gccgtttttc tggatgttgg
    20281 cgatggcgtg cagggtcagg gtcgtcttgc cgctcgactc cgggccgtag atctccacga
    20341 tgcggccgcg cgggtagccg ccgatgccga gggcgatgtc caggctgagc gagcccgagg
    20401 agatggccgg cacctcatca tggagggatt gcccctcctt gaggcgcatg atggcgccct
    20461 tgccgtattc cttctccacg ctcgcgatgg cgagttccag ggcggcgtgc ttctgcttgc
    20521 tgttcttttc ttccgacatg gggacctcgg ggcggtgaga gggggcgcgc ggtcagctga
    20581 tgcgggaact gtttactggc cggctgttca ggaagcaaga tgcccgcatc caggctgaga
    20641 cagggaatga ccgagcgccg ggcgtgatga acgggaaggt gcggacaggg cgaagaggcc
    20701 acggggttcc tggtggagcc cccggatggg gaggctgccc cacgttggac agggcgccgg
    20761 gaaccctggc acggggctca gaatagaccg atcgagaact ggaaggcgcc gaagtcttcc
    20821 cagggccgtc ggagcaggtt gatgccgtag tcgagggcga gcgggccgat gggggtgccg
    20881 atgcgcaggc ctgcgccggc ggcatagcgc aaggcgaaga ggtcgaactc gcgcgggtcc
    20941 gc
//
