LOCUS       NZ_CP012159            20978 bp    DNA     circular CON 02-MAY-2024
DEFINITION  Chondromyces crocatus strain Cm c5 chromosome, complete genome.
ACCESSION   NZ_CP012159
VERSION     NZ_CP012159.1
KEYWORDS    RefSeq.
SOURCE      Chondromyces crocatus
  ORGANISM  Chondromyces crocatus
            Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae;
            Chondromyces.
REFERENCE   1  (bases 1 to 11388132)
  AUTHORS   Zaburannyi,N., Bunk,B., Maier,J., Overmann,J. and Mueller,R.
  TITLE     Genome analysis of myxobacterium Chondromyces crocatus Cm c5 reveals
            a high potential for natural compound synthesis and the genetic
            basis for the loss of fruiting body formation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11388132)
  AUTHORS   Zaburannyi,N., Bunk,B., Maier,J., Overmann,J. and Mueller,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2015) Department of Microbial Natural Products
            (MINS), Helmholtz Institute for Pharmaceutical Research Saarland
            (HIPS), Campus E 8.1, Saarbruecken, Saarland 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Newbler v. 2.6, HGAP SMRTPortal v. 2.2.0
            Assembly Name                     :: Cm_c5_Newbler_HGAP3_v13
            Genome Coverage                   :: 366x
            Sequencing Technology             :: Illumina, PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001189295.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 07:18:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,280
            CDSs (total)                      :: 8,172
            Genes (coding)                    :: 8,124
            CDSs (with protein)               :: 8,124
            Genes (RNA)                       :: 108
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 96
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 4 of 48
            Pseudo Genes (incomplete)         :: 44 of 48
            Pseudo Genes (internal stop)      :: 3 of 48
            Pseudo Genes (multiple problems)  :: 2 of 48
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:43:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2091669
            Orig. end                         :: 2112647
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012159.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20978
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20978
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20978
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10978](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10978)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(743..758)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(1822..2538)
                     /locus_tag="CMC5_RS07840"
                     /old_locus_tag="CMC5_015860"
     CDS             complement(1822..2538)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013873.4"
                     /locus_tag="CMC5_RS07840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015860"
                     /product="isopentenyl transferase family protein"
                     /protein_id="WP_050429816.1"
                     /transl_table=11
                     /translation="MKAHCIVGATGTGKTARATSLARQTGAPVLVLDRFQVFEDLASGT
                     GRPLSREVAGTTRLYLGHRYMMDGELTRQDALLDFLRTVGKLAVDHDFIILEGGSISLN
                     EALIEESLLGTTGVTVERMRMTSVKAYEQGLRRRARMMLTPSAERPSMIEELARGWDNP
                     RLRAFLSSITGYDAIVDHCEQAGIEPAELAAGPVDPVLIDEVVLSHMKYAAKQTAAFNQ
                     LFPEQSSFPGCQPCTA"
     gene            complement(2535..2828)
                     /locus_tag="CMC5_RS07845"
                     /old_locus_tag="CMC5_015870"
     CDS             complement(2535..2828)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS07845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_015870"
                     /product="hypothetical protein"
                     /protein_id="WP_050429817.1"
                     /transl_table=11
                     /translation="MKKEASGLVEFGSFRRASDLAHALMGNAEIALATFVQLTLTSPQS
                     RHRMPEPDGFRGFAPQEGAHHCGSLATTTDSDHGVAPRSKLEQELFREGEGP"
     gene            3483..4367
                     /locus_tag="CMC5_RS07850"
                     /old_locus_tag="CMC5_015880"
     CDS             3483..4367
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS07850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_015880"
                     /product="hypothetical protein"
                     /protein_id="WP_050429818.1"
                     /transl_table=11
                     /translation="MRIAFVAFDFHRLHASGSKFDESIPLKEAFASRGASLEVIAAPDA
                     SVGWGRFDAVLPLGCWGYHEDVQGFLAWVESLEAAGARLINAPALLRWNVDKAYLLRLQ
                     ASGAHVAPFLHFEAHSRPDLGHAIEAEGWSRFVLKPTISANAWKTLVADAPPGSEATQL
                     AEDILRTSGLLVQPFFEEIPRHGELSILFFGGKLSHAVVKLPRAGDFRSQPSHGASVLR
                     AELPPTVLERAKAVLRAVPGEPVYARVDGFLRDGEFQLVELELIEPYLFLDGAPPEACG
                     RFCDAVLQHLQAR"
     misc_feature    3522..3540
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.01"
                     /tool="antismash"
     gene            complement(4378..5046)
                     /locus_tag="CMC5_RS07855"
                     /old_locus_tag="CMC5_015890"
     CDS             complement(4378..5046)
                     /EC_number="2.5.1.25"
                     /GO_function="GO:0016432 - tRNA-uridine
                     aminocarboxypropyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015875.4"
                     /locus_tag="CMC5_RS07855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015890"
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="WP_050429819.1"
                     /transl_table=11
                     /translation="MLRASVTDPLALLPGPPAIRTRRIPRCTACALPPPLCLCGELHAM
                     AVTPRTSVVLLMHHAELYKSTSTGRLLHRVIPSAHLRLRGAPEGPAPAPLLPERRLLLF
                     PDPSAPVISPELVNDEPVALLIPDGTWKQARRITQRDPAVLGAQRVNLPPGAPSRYGLR
                     RSPRPEALSSFEAAARALGVLEGEAIETRLMAAFDLWVERSREVREHGEQIAPSCRAGA
                     "
     gene            5119..5688
                     /locus_tag="CMC5_RS07860"
                     /old_locus_tag="CMC5_015900"
     CDS             5119..5688
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020741140.1"
                     /locus_tag="CMC5_RS07860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015900"
                     /product="hypothetical protein"
                     /protein_id="WP_050429820.1"
                     /transl_table=11
                     /translation="MKRRAVLASLSLAAAGGLAWKFLRFPPDTTPEGAYLRIARNIGRG
                     EPRVVFSYLEDRAQHAAYTIRDYRKKARDRVAETYPEPERERLLALYGPAADATDGADV
                     WVEMATRLGWITRLRRDLSGIAKVDLAGERATIETARGTRYPFRLRENGMWGTSLFTAE
                     LVAEAERAARDWDVVEQAALDYERAR"
     gene            complement(5737..6198)
                     /locus_tag="CMC5_RS07865"
                     /old_locus_tag="CMC5_015910"
     CDS             complement(5737..6198)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012233061.1"
                     /locus_tag="CMC5_RS07865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015910"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_050429821.1"
                     /transl_table=11
                     /translation="MNTIRRVSPAEAKKLIDEEGYIYVDVRSEPEYASGHPAGAKNLPF
                     QNVGPGGMQANQDFLPVVQALFPKDAKLILGCRSGQRSLRAAEALLGAGYTDVIDQRAG
                     FDGRRDMFGKLIEPGWSYAGLPVAQATPGGSYAELRREAGPQGAQLPSA"
     gene            6285..7013
                     /locus_tag="CMC5_RS07870"
                     /old_locus_tag="CMC5_015920"
     CDS             6285..7013
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012233062.1"
                     /locus_tag="CMC5_RS07870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015920"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_050429822.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-16,
                     bitscore: 59.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHGARIAVVLPARDEEAWIREAVSCVPDFVDQVIVVDDASRDRT
                     AAVAAAAGDERLRVSTHATCRGVGAAIVTGYRVALAQGAQVTAVMAGDAQMDPRDLPRV
                     VAPVALDRADYVKGNRLSHPDVWSAMPLGRLVGTATLAALTRRAAGLDALSDSQCGYTA
                     VSTRALEALDLDALWPRYGYPNDLIVSLAAAGMRIQEVPVRPVYRGEASGLRIGHLATI
                     LRVIVRSRQRASEARRSGIA"
     gene            7266..9641
                     /locus_tag="CMC5_RS07875"
                     /old_locus_tag="CMC5_015930"
     CDS             7266..9641
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012233063.1"
                     /locus_tag="CMC5_RS07875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015930"
                     /product="ATP-binding protein"
                     /protein_id="WP_245678342.1"
                     /transl_table=11
                     /translation="MTVGRGATVERMHGGGRGDEEAPIRADRGSGEGSAARVRAQPPLR
                     LRAAGSVSTPPTARSGVDTLSLQRMRPRSSFRLRVVAYAFGIELPFSLLVPVAYLRLLN
                     IDDLVEQTRVLTLIGALHLLKTGALIAVLMRMLRPIDRLRSFGAGMPTSRSDAAGRSSS
                     EPGSIPPSSLILNAGRAAYETPLAFGVLWAVSWALFYFPVTAALPMLAPSQGVAGPRLM
                     AALLLFSLALFAAAMPLGYSILGRLLSPAAGLISLAARERDLAVPGRSFSVAARLVLLG
                     VCLAVAPTSWMVAMVLMEVGRPAEPGGWISLVIFSIVAVSWAPVCAGFIAGALATPLRQ
                     VGAVIEKIIQRGDAERLERIPIHFKDEIGALAGGVNAMVDRLQESSARIRSYLAERERL
                     LEDEAQRAAQLQAILDNLVEGVMACDAEGKLTMVNASALRLLGLPTPGASGGVPSVPAC
                     SVEELHELARMSHRDGRAFSRDELPMIRSLAGETIAAEEQVLTDPGTQREVFLLTSAAP
                     IRGADGAILGAVTVARDVTESRELELVKDQFIRVGAHELKTPVAIMKGYALALLRAGAD
                     LPPARRQMLEAIDRGADRINRIVDDLLAISQITLDQFAVFQERVDLGRLVSSAVERVST
                     TAARHHIRLRLPAGKPIVARGDPERLRQVLASLLDNAVKYSPEGGEVEVSVAIAPRCSP
                     TDRTSDPARSGPGLEAIVSVRDHGIGIPSAKQDRIFQRFFRAHTDTTHDYGGMGVGLFL
                     ARDMITRQGGRMWFESEECQGSVFHFAVPLEEGELAHG"
     gene            9645..10013
                     /locus_tag="CMC5_RS07880"
                     /old_locus_tag="CMC5_015940"
     CDS             9645..10013
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012233064.1"
                     /locus_tag="CMC5_RS07880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015940"
                     /product="response regulator"
                     /protein_id="WP_050429823.1"
                     /transl_table=11
                     /translation="MTGKQAKKVLVIEDDQDLVALVSLLLQGDGYSVEIAGNGREALDA
                     LARELPDVILLDMKMPVMNGPEFARELEVRYGHQAPIIVLTAAADAHRRAAEVGADAWL
                     GKPFDPDVLLSTVRRYAG"
     gene            complement(10001..10978)
                     /locus_tag="CMC5_RS07885"
                     /old_locus_tag="CMC5_015950"
     CDS             complement(10001..10978)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.4"
                     /locus_tag="CMC5_RS07885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015950"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_050429824.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.1e-07,
                     bitscore: 30.2, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-09, bitscore:
                     36.6, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGGAVLGGDRKLVDDASTLFGSSRFRALSDDTLKDEDNAAWVLD
                     LPDEARQAWLSRIHWIRLVDRLAENERFEPERRRFRSFLEGWRRLRQSDFIDPADPFHR
                     ELSSLRDAWLIPTRGDVGPPSKQLNPRVVAAWDAYLEALEEYHAPEVQVRTMVEHDEML
                     FRLSGRIFQLMPFLTTVHWDAAGEFGRLDQFFNNLRDLQEDAEHGICYLPVDLLRRFGV
                     AREEVLSGRCASTPAFRAMMRFWVGEHLAALRERARPFIEAEGVHPSLEIMRSWSLRRH
                     ARIERVLRTLDFDYRRFPTRYWAEVRRGLLVSRLRSSSACPQPA"
     misc_feature    complement(11175..11190)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.51"
                     /tool="antismash"
     misc_feature    11355..11373
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.25"
                     /tool="antismash"
     misc_feature    complement(11649..11664)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.35"
                     /tool="antismash"
     gene            complement(11704..12027)
                     /locus_tag="CMC5_RS07890"
                     /old_locus_tag="CMC5_015960"
     CDS             complement(11704..12027)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS07890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_015960"
                     /product="hypothetical protein"
                     /protein_id="WP_050429825.1"
                     /transl_table=11
                     /translation="MFTAWLSAFLFTQCVEMPIYARCARTGWGPAFGASALTHPIVWFV
                     MPELLPGNYWVMVAVAEAFAVVAEAVYLRFGFRLERALLWSLLANGASFSIGLLSRHAF
                     GWP"
     gene            complement(12041..12319)
                     /locus_tag="CMC5_RS07895"
                     /old_locus_tag="CMC5_015970"
     CDS             complement(12041..12319)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039620.3"
                     /locus_tag="CMC5_RS07895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015970"
                     /product="DUF5985 family protein"
                     /protein_id="WP_156338342.1"
                     /transl_table=11
                     /translation="MNEYISGASTLGYAVVAMFFLRFWRQTNDRLFFIFSAAFWLLALG
                     RIAVHAVQVADDHLHYLYLLRLLAYVLILYAIIDKNRRPSARQPLSG"
     gene            complement(12347..12637)
                     /locus_tag="CMC5_RS07900"
                     /old_locus_tag="CMC5_015980"
     CDS             complement(12347..12637)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015184457.1"
                     /locus_tag="CMC5_RS07900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_015980"
                     /product="DUF5985 family protein"
                     /protein_id="WP_050429827.1"
                     /transl_table=11
                     /translation="MAAAVYLLCALTSIACMVLLLRGYAKNRVRLLLWSGLGFAGFAVN
                     NILLFVDLVLLPTRISLAMPRNAFALLGLLLLLYGLLWDMREGTRERRGEP"
     gene            complement(12640..12993)
                     /locus_tag="CMC5_RS07905"
                     /old_locus_tag="CMC5_015990"
     CDS             complement(12640..12993)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CMC5_RS07905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CMC5_015990"
                     /product="hypothetical protein"
                     /protein_id="WP_050429828.1"
                     /transl_table=11
                     /translation="MHISSIELLEVLLLLRKSGEREWRPADVAREIGSSMMSIRDRLAN
                     LAARDLIATREVDDDLWYHYAPESEVRHVVDELARAYKERRLTIIDMIYARQLPGDIET
                     FSDAFLIRKKDGD"
     misc_feature    13085..13102
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            complement(13088..15274)
                     /locus_tag="CMC5_RS07910"
                     /old_locus_tag="CMC5_016000"
     CDS             complement(13088..15274)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012233894.1"
                     /locus_tag="CMC5_RS07910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMC5_016000"
                     /product="response regulator"
                     /protein_id="WP_063796236.1"
                     /transl_table=11
                     /translation="MSTPSGRPSGTRVPQSSAPSGAGPVDILIVDDKPDKLLALETILE
                     ELGQNIVRAMSGRDALRHVLQQEFAVILLDINMPGMDGFETAELIRQHRTSRHTPIIFV
                     TAFGEEPNALKSYSLGAVDYILAPVDPEVLKTKVGVFVELFKKTAEVKRQAEALQRRAA
                     QLNKLANASIAINASLSLDATLRAITESARDILEAKQAFSVATLGHPGERPRVAVSLAE
                     ELAPAFRGYRPALRSTRAPGTGLTRLHDVLYARNRPIRLTEAELKAHPEWQPDEPMGPP
                     LRGVLAAPLTEVTGRNMGFIQLSDRVQGEFTEDDEAILVQLAQLGSIALQNGLNLEARE
                     ANRLKDEFLATLSHELRTPLNAILGWTRLLQTSPMDPAKFERGFEVIERNVNAQVRMIE
                     DLLDISRITTGKMKLSVATVELGPLVEAVIDTLRPAAEARGVTLKAEIDGCEIQGDSER
                     LQQVISNLLSNAIKFTPRGGGVDVSLSLGEGEVTLVIHDTGEGINPDFLPFVFERFRQA
                     DSTSKRAQGGLGIGLALVRHIVELHGGSVLADSAGQGQGSTFTVRLPSIPSTARSADPA
                     LAKPSEDDANTLEGLYVVVVEDEDDTREMLGEVLRRHRAEVTTVASASEALQIISTRRP
                     HVLVTDVAMPNEDGFELIRQLRNLGPKAGGDVPALALTGYARKEDHARALAAGFQMHAS
                     KPIEPSELVAAIACLAGGSGIIRALGRPPRFTVP"
     misc_feature    15283..15297
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.63"
                     /tool="antismash"
     misc_feature    complement(15512..15526)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(15529..15538)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    16108..16117
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    17006..17021
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.19"
                     /tool="antismash"
     misc_feature    complement(18074..18090)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.28"
                     /tool="antismash"
     misc_feature    20696..20711
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.32"
                     /tool="antismash"
ORIGIN
        1 tcgctgagcg acattgccta cggcgccgag ggacgtcttc tcatgctcct ggggagccgc
       61 ctggagagct accggcggat cggcctccgg gccgtgctgg atcgccagtg ggaactcgaa
      121 gggtacggca tgacgacgct ccatcagggg cggctcgtcg ccgtgaagtg cgtcgaggga
      181 gaccgtgacg gcatcacgct ctacgggttc gatggggcga cgttgcggcg tcttgcgcgc
      241 gtccgcgcga acgcgggtgt gctcttcggc agcgacgagc gcgtgttctt cgagcacaac
      301 ggggccgagg cggagctcta cgagctgacg gggacgggcg cgctgctcga cgccctggaa
      361 ggccgcccca cgtcctttgc cgagatcccg gtgaccgtgc gcttcgatcc ttcggatgtc
      421 cagggcgcgg agagcgaggc gaagggcctc agcgacgagg cgcctctcga agatctggtg
      481 gcggaggacg aagaagacga cgagcaggaa gggggagccc cgaagaagcc gcaagacttc
      541 gtactcgagc ccgctccagg ccggatcggc gttcggttcg tgggcgcgaa gagtccagtg
      601 cggcgctcgc gtgaagaggc catcccgaag gaggtgcgtg ccctgttcgg cgcccggagc
      661 aacgtctcca aggcgggtga aggggacctg tacttcggct ggaagaagga caagcgcagt
      721 gcgttccgct tcgcaattgc gcgggacggg gcggtgaccg agaccgagct caagtcgagc
      781 gccccctcga cgctgatcac gctggtggcg ggtgagccga cggcgctcgt ggccacggac
      841 gacgacagca agctgtggaa ggtggcgctg gatacgggca aagcgagcct ggtctgggat
      901 ttcagccggg agcgagacga gaaggagatc tacgtcctcc aggggctggc ccacggccgc
      961 gtcctggtcg ggacggcctc cgagacctgg atcttctcgc tggcaggacc acagcccacc
     1021 gtcgaggtgc gagggcagct ggacacgcgc gaggcagacc ccttctgcgg ggggcgtgtg
     1081 gtcgtcctgc aagcgcggaa cggtcgaccg ctgcggctgt ggggcatctt tccggccggg
     1141 atcaagacgc tggctggcct cagggtgcgg ccggcgagcg tgcacacgtc ggagggaaag
     1201 ctctacgtga gcgcagaggc ggagctgggc tggttcgaga tcctcaacgt ggaggacgcc
     1261 tggactgctg ccgagcgtga tgtcgaaggg acgcgctacc cgcacgtgga tctcgttcgc
     1321 gccgttgctc ccgaggaaga cgaggtgggt gacgaggacg acgaggacga cgacgacgag
     1381 agcgaggacg cggaagagaa ggacgaagac agcgagagct acgacggcgg cgacgacgag
     1441 gacgacgacg agaacgacga cgacgacgac gacgacgacg acgattgagg tcgggaagcg
     1501 agccgcagtg cccccgcgcc tcgcttcgtg ccgcggggag tcccgatctc gagccacgcg
     1561 ctggatcgcc gcgtgacggc gtgagcgacg ccttgccgac gaggcgatgc gtcgctcggt
     1621 ggcatcacat tcgacgtctg gggtgggcgt actggacggc gcgaggtcgc acgggcattc
     1681 cgcgccggac cgggctcgtc tcgaagcgct ccggctcggg tgaggcgcgc cctggggtgg
     1741 cccgaggccg cagccgcgag cggcgcgcca acctcgaaag ccggcctgtt cgagcgaagc
     1801 tcctgctcgt gatgtcgcgc gtcaagcggt gcatggctgg catcctggga agctggactg
     1861 ctccggaaag agctggttga aggccgcggt ctgcttcgcc gcatacttca tgtgcgagag
     1921 aacgacctcg tcgatgagca ccgggtcgac agggccagcg gcgagttcgg cgggctcgat
     1981 gccagcctgc tcgcagtggt ccacgatggc gtcatagccc gtgatggacg agaggaaggc
     2041 tcgcagccgc gggttgtccc agccgcgcgc gagctcctcg atcatggaag ggcgctcggc
     2101 gctcggggtg agcatcatgc gcgcgcggcg acggagaccc tgctcgtacg ccttcacgct
     2161 ggtcatgcgc atccgctcga cggtgacacc ggtcgtgccg agcaagctct cctcgatcag
     2221 cgcctcgttc agggagatcg aacctccttc gaggatgatg aagtcgtgat cgacggccag
     2281 ctttcccacc gtgcgaagga agtcgaggag ggcgtcctgc cgcgtgagtt ccccgtccat
     2341 catgtagcgg tgaccgaggt agagccgcgt cgttccagcc acctcgcgcg agagcggccg
     2401 gcctgtcccc gacgcgagat cttcgaagac ctggaatcga tccagcacca ggaccggagc
     2461 ccccgtttgc cgcgccagcg atgtggctcg cgccgtcttg ccggtgcctg tcgccccgac
     2521 gatacaatgt gctttcatgg cccctcccct tcacgaaaca gctcctgttc gagcttcgaa
     2581 cgaggtgcga ctccgtgatc cgaatcggtt gtcgtcgcca agctgccgca gtgatgcgcg
     2641 ccttcttggg gggcaaagcc tcgaaagccg tctggctcgg gcatccggtg tcgagattgc
     2701 gggctcgtca gggtgagctg cacgaacgtc gcgagcgcga tctcggcatt tcccatcagg
     2761 gcatgcgcga gatcgctagc acgacggaac gagccgaatt cgacgaggcc gctggcctct
     2821 ttcttcatgg ctaccccccc cggagtatcg atgaagcaga ccgtggttcg accctgccga
     2881 tcgccacgga tgcctgacaa cttctaggct gccacgattc cctatgtctg ggaacaggga
     2941 agttcaccca ggaccgagcc cgacctcgca cgtcatcaac cactccgatg tcgtcatcga
     3001 catccgcgag gggtgtcgac ctcgactcgt cgtgggtcaa tctcccttca ttgaacgcct
     3061 ctacaccatt gttccgtgct ggttgctcga cccgcgcggc ccacgcttgg ctcagctcat
     3121 agttcgatgc tttgcacagg gttcgatcaa cctgtgggtt ggaacgggag cggctcgtcg
     3181 agcgcgcaac gagatttgcg gtgccacgag acgtgaggct gcgctcggag tcggaccccg
     3241 ggatgagtcc acgcttctca atgcgctgcc accatacgct tccgcgtcat caagggctgt
     3301 ctccaggctg cggacataac gactccggtc gtgatgccct gtcgaacgtc tggcgacctt
     3361 ggcgggttgc ctcggtctcc tttcgaagcg cgaactcctc aggaggcacg gcatgcatgg
     3421 tctccggcac ccttcggggc ctgcttgctc cccgtggcgc ccctctgcta gcaggatgtc
     3481 ccgtgcgcat cgccttcgta gcattcgatt ttcatcgact tcatgcgagc gggtcgaagt
     3541 tcgacgaatc gatccccctg aaggaggcct ttgcctctcg aggggcctcc ctcgaagtga
     3601 ttgcagctcc cgacgcctcc gtgggctggg gacggttcga cgccgtcttg cccctgggat
     3661 gctggggcta ccacgaggat gttcagggct ttctcgcctg ggtggagtcg ctcgaggccg
     3721 caggtgcgcg tctgatcaat gcgccagccc tcctgcgctg gaacgtggac aaggcctacc
     3781 tccttcgcct ccaggcttcc ggcgcccacg tcgcgccgtt tctccatttc gaggcgcaca
     3841 gccgtcccga cctcggacac gcgatcgagg cggaggggtg gtcgcgcttc gttctgaagc
     3901 cgaccatctc cgcgaatgca tggaaaacgt tggtggcaga tgcgcctcca gggtcagagg
     3961 ccacgcagct cgccgaggac atcctccgca cctcgggtct tctcgtgcag cccttcttcg
     4021 aggagattcc gcgtcacggt gagctgtcga tcctgttctt cgggggaaag ctgagccacg
     4081 ccgtcgtcaa gctccctcgg gctggtgatt tccgttcgca acccagccat ggagcctcgg
     4141 tcctccgagc cgagctgccc ccgaccgtgc tggaacgagc caaggcggtg ctgcgcgccg
     4201 tccctggtga gccagtttat gcgcgcgtgg atggcttcct ccgcgacggg gagtttcagc
     4261 tcgtggagct ggagctcatc gagccgtacc tcttcctcga cggagccccc ccggaggcct
     4321 gcggtcgctt ctgtgacgcc gtgctgcagc acctgcaagc gcgctgaggc gtcagaacta
     4381 ggccccagct cggcatgacg gagcgatctg ctccccatgc tctcggactt ccctggagcg
     4441 ctccacccag aggtcgaacg cagccatgag gcgagtctcg atggcttccc cttccagcac
     4501 ccccagtgcg cgagcggcgg cctcgaagct ggagagcgcc tcggggcgtg ggctgcgccg
     4561 gagcccgtag cgactcgggg cgcccggtgg gaggttcacc cgctgggcac cgaggaccgc
     4621 cgggtcgcgc tgggtgatcc ggcgcgcctg cttccacgtc ccatcgggga tgagcaacgc
     4681 gacgggttcg tcgttgacca gctcgggcga gatcacgggc gccgagggat ccggaaacag
     4741 caggaggcgg cgctccggga ggagaggggc cggggctggg ccctcgggcg ccccgcgcag
     4801 gcgcaagtgc gcgctcggga tcacccggtg gagcaggcgc ccggtgctgg tgctcttgta
     4861 cagctccgcg tggtgcatca gcaggaccac ggaggtgcgg ggcgtgacgg ccatcgcgtg
     4921 gagctcgccg cacaggcaca gcgggggtgg cagcgcgcaa gcggtgcagc gcgggatccg
     4981 gcgtgtccgg atggccggtg ggcctggaag gagggcgagc gggtcggtca cagaggcccg
     5041 cagcatgcca cgggacgccc gtcgatcgtg gctgtcccgg cagggtgtgg tacggatgcg
     5101 ccctccctcg ctcgaccgat gaagcgccgc gccgtcctcg cctccctctc ccttgccgcc
     5161 gccggaggac ttgcgtggaa gttccttcgt tttcccccgg acaccacccc ggaaggcgcc
     5221 tacctgcgca tcgcccgcaa catcggccgc ggtgagccgc gggtggtgtt ctcctatctg
     5281 gaagaccggg cacagcacgc ggcgtacacc atccgcgact accgaaaaaa agcgcgtgac
     5341 cgcgtcgccg agacctaccc cgagccggag cgagaacgtc tgctcgccct ctacggaccg
     5401 gccgccgatg ccaccgatgg tgccgacgtc tgggtggaga tggcgacacg cctcggctgg
     5461 atcaccaggc tgcgccggga cctctcgggc atcgccaagg tcgacctcgc aggcgaacgc
     5521 gcgaccatcg agacggcccg agggacgcgc taccccttcc gcttgcgaga gaacggcatg
     5581 tgggggacct ctctcttcac ggccgagctc gtggccgagg cggaacgagc cgcgcgcgac
     5641 tgggatgtcg ttgagcaggc ggcgctggac tacgagcgtg cgcgttgagc cgcatggccg
     5701 ggccgggccc cttcctccgg agcccaacct ggcgtttcag gccgatggaa gttgcgcgcc
     5761 ctgggggccg gcttcccggc gcagctcggc gtacgagcca cctggtgtgg cctgcgccac
     5821 cggcaacccc gcgtagctcc agccgggctc gatgagcttg ccgaacatgt cacgccgccc
     5881 atcgaagccc gcgcgctgat cgatgacgtc ggtgtacccg gcgccgagca aggcctctgc
     5941 cgcgcggagc gagcgctgac cggagcggca cccgaggatg agcttcgcgt ccttcggaaa
     6001 cagggcctgc accacgggaa ggaagtcctg gttcgcctgc atccccccgg gccccacgtt
     6061 ctggaagggc aggttcttcg ccccagccgg gtgtcctgac gcgtactcag gctcgctgcg
     6121 aacatccacg tagatgtaac cctcctcgtc gatcagcttc ttggcctccg caggtgagac
     6181 gcgccggatg gtgttcatgg cggacgattt aacccgtccg ggtgggcctc gccaaccaac
     6241 cctcccgctt gccagccacg aggaggcgcg gtagcggagc ccccgtgctg catggagcgc
     6301 gcatcgccgt ggtcctcccc gcgcgcgacg aggaggcgtg gatccgcgaa gcggtgagct
     6361 gcgtccctga tttcgtggat caggtgatcg tggtggacga tgcaagccgc gatcgcacgg
     6421 cggccgtcgc tgccgcggcg ggcgacgagc ggcttcgcgt ctcgacccac gccacctgtc
     6481 gaggcgtcgg agccgccatc gtgaccggct accgggtcgc cctggcgcag ggggcacagg
     6541 tcaccgcggt catggcgggc gatgcccaga tggatccgcg cgacctgcca cgcgtcgtcg
     6601 ctccggtcgc gctggatcgg gccgactacg tcaaggggaa ccggctgtcc catccggacg
     6661 tctggagcgc catgcccctc ggacgtctcg tcggcacggc cacccttgcc gccttgaccc
     6721 gccgagcggc tggcctggac gctttgtcgg acagccagtg tggctatacg gccgtctcga
     6781 cgcgcgcgct ggaggcgctc gacctggacg cgctgtggcc gcggtacggc taccccaacg
     6841 atctgatcgt atcgctcgcc gctgccggga tgcggatcca ggaggtcccc gtgcggcccg
     6901 tgtaccgagg cgaagcgagc gggctgagga tcggccatct cgcgaccatc ttgcgggtga
     6961 tcgttcggag caggcagagg gccagcgagg cgcgtcgctc aggaattgcc tgaggcagga
     7021 ccccgagctt caggaaaggc ccgaactgtc cccttccatg tcgccctgta ccgacctgac
     7081 gcccctggcc cccttccagg gagatggcac gctgagcgtg cccgtggttt caggtttccc
     7141 tcctcctcgg agccctgttt gccagcagtg ccctggggtc gcgcaaaggg agcgcccgag
     7201 cgggctgccg catcatctta gggaggcagt tcgtcgcggg gagcgacgcg ctcgcgaaga
     7261 ggggggtgac ggtgggcagg ggggcgacgg tggagcgcat gcacgggggg ggtaggggcg
     7321 acgaggaggc cccgatccgc gccgaccggg gcagcggcga ggggagcgct gcgcgggtgc
     7381 gtgcccagcc ccccttgcgc cttcgagccg cagggagcgt ctcgaccccg ccgacggcgc
     7441 ggtccggggt cgataccctc tctttgcagc gaatgcggcc gcgctcctcc tttcgtctcc
     7501 gcgtcgtggc gtacgcattc ggcatcgagc ttcctttcag cttgctcgtc ccggtcgcgt
     7561 acctccggct gctcaacatc gacgatctcg tcgagcagac ccgggtcctg acgctcatcg
     7621 gggccctcca tctcctgaag accggagccc tcatcgcggt cctgatgcgt atgctccggc
     7681 cgatcgatcg gctccgcagc ttcggagcgg ggatgccgac gagccgttcc gacgctgcgg
     7741 gtcggagcag cagcgagcca ggtagcatcc ccccctcctc gctgatcctg aacgccggac
     7801 gcgccgctta cgagacaccg ctcgcgttcg gtgtcctctg ggcagtgagc tgggcgctgt
     7861 tctatttccc ggtgaccgcg gcgctcccca tgctcgcgcc gagccagggg gtggcggggc
     7921 ctcgcctcat ggcggccctc ctcctgttct ccctggccct cttcgcagcg gcgatgcccc
     7981 tcggctacag catcctgggg aggctgctct ctcccgcagc cgggctgatc tcgctcgcgg
     8041 cccgagagcg cgacctggcc gtccctggac gcagcttctc cgtcgccgcg cggctggtct
     8101 tgctcggcgt ctgcctcgca gtcgcgccga cgagctggat ggtcgcgatg gtgctgatgg
     8161 aggtgggccg cccggcagaa cccggtggct ggatcagcct ggtgatcttc tcgatcgtgg
     8221 ccgtgagctg ggcgcccgtg tgcgcgggct tcatcgctgg agccctcgcc acgcccctgc
     8281 ggcaggtcgg cgccgtcatc gagaagatca tccagcgcgg tgacgcggag cggctggagc
     8341 ggataccgat ccacttcaag gacgagatcg gagccctcgc cggtggcgtc aacgccatgg
     8401 tcgaccgcct gcaggagtcg agcgcccgca tccggagcta cctcgccgaa cgagagcgct
     8461 tgctggagga cgaagcgcag cgcgccgcgc agctccaggc catcctcgac aacctggtcg
     8521 agggcgtcat ggcctgcgac gcggagggga agctcaccat ggtcaacgcc tctgcgttgc
     8581 gcctcctcgg cctcccgacg cctggcgcga gcggcggcgt gccctccgtc ccggcgtgct
     8641 ccgtcgagga gctgcacgaa ctcgcgcgga tgagccacag ggacggccgc gccttctccc
     8701 gcgacgagct ccccatgatc cgctccctcg cgggcgagac catcgcggcc gaagagcagg
     8761 tcctgaccga ccctgggacc cagcgcgagg tcttcctcct gaccagcgcc gcccccatcc
     8821 gcggcgccga cggagccatc ctcggcgccg tcaccgtggc gcgtgacgtc accgagtccc
     8881 gcgagctgga gctcgtgaag gaccagttca tccgcgtggg agcccacgag ctgaagacgc
     8941 cggtcgcgat catgaaaggg tatgcgctcg ccttgctccg cgcgggcgcc gatctccccc
     9001 ccgcgagacg gcagatgctg gaggccatcg accgaggcgc cgatcgcatc aaccgcatcg
     9061 tcgacgacct gctcgccatc tctcagatca ccctcgatca gttcgcggtc ttccaggagc
     9121 gcgtcgacct cgggcgcctc gtctccagcg ccgtcgagcg cgtctccacg accgccgcgc
     9181 gtcaccacat ccggctacgc ctccccgctg gcaagccgat cgtcgccagg ggagacccgg
     9241 agcgactccg ccaggtgctc gcgagcctcc tcgacaacgc cgtcaagtac tcccccgagg
     9301 gcggtgaggt cgaggtgagc gtcgccatcg ccccccggtg ttcaccgacc gaccgaacgt
     9361 ccgatcccgc ccggagtggc cctgggctcg aagcgatcgt ctccgtccgc gatcatggaa
     9421 tcgggatccc gagcgccaag caggatcgca tcttccagag attcttccgc gcccacaccg
     9481 acaccacgca cgactacgga gggatgggcg tcggcctgtt cctggccagg gacatgatca
     9541 cccgtcaggg agggcgcatg tggttcgaga gcgaggagtg tcagggcagc gtgttccact
     9601 tcgccgtacc cctcgaagag ggggagctgg cccacgggta ggtcatgacg ggcaagcaag
     9661 ccaagaaggt cctggtgatc gaagacgacc aggatctcgt cgcgctggtc tctctgctcc
     9721 tccaaggcga tggctacagc gtggaaattg cgggcaacgg acgtgaggcg ctggatgcgc
     9781 tcgcccgtga gcttcccgac gtgatcctgc tcgacatgaa gatgcccgtc atgaacgggc
     9841 ccgagttcgc ccgggaactg gaggtccgct acggccacca ggctccgatc atcgtgctca
     9901 ccgcggccgc cgacgctcat cgccgcgccg ccgaggtcgg cgccgacgcc tggctgggca
     9961 agcccttcga ccccgatgtc ctgctgtcga cggtgcgccg ctatgcgggc tgaggacacg
    10021 ccgacgacga gcggagccgg ctgaccagga gaccgcgccg cacctcggcc cagtaccgcg
    10081 tcggaaagcg acgatagtcg aagtcgaggg tccgcaagac gcgctcgatg cgtgcgtgcc
    10141 gccgcagcga ccagctgcgc atgatctcga gcgaggggtg cacgccttcg gcctcgatga
    10201 acggacgagc ccgctcccgc aaggcggcga ggtgctcacc cacccagaag cgcatcatgg
    10261 ccctgaaggc cggcgtcgag gcacagcgac ccgagagcac ctcctcgcgc gccaccccga
    10321 aacgacggag gagatcgacc gggaggtaac agatgccgtg ctcggcatcc tcctgcagat
    10381 cccgcaggtt gttgaagaac tgatcgagcc gcccgaactc tccagcggca tcccagtgga
    10441 ccgtcgtgag gaacggcatg agctgaaaga tcctgccgct caggcggaac agcatctcgt
    10501 cgtgttcgac catcgtccgg acctgcacct cgggcgcgtg atactcctcg agcgcctcga
    10561 ggtaagcatc ccaggcggcc acgacgcgcg ggttcagctg cttcgaggga gggcccacgt
    10621 ctcctcgcgt cgggatgagc cacgcgtcgc ggaggctcga cagctcgcgg tgaaacgggt
    10681 ccgccggatc gatgaagtca ctctggcgca ggcgccgcca cccctccagg aaggagcgga
    10741 atcgtcgcct ctcgggctcg aaacgttcat tctccgcgag ccgatcgacc agacggatcc
    10801 agtgaatgcg agagagccac gcctgcctcg cctcgtccgg cagatccagc acccacgcgg
    10861 cgttgtcctc gtctttcagc gtatcgtccg atagcgcgcg aaaacgagaa gagccgaaga
    10921 gcgtcgaagc atcgtcgacg agcttccggt ctccgccgag caccgcgcca ccacgcatcg
    10981 ccggccctcg cgccgctcga catgggggca caggggcagc cgaagccggg ctgtccgact
    11041 gagcatcccg gtgtcgcccc gggaccatga taccaaccga ggcttgcgtg gaatccagcg
    11101 tcataggctc gctcaggtca aagtggtcac tgaaacggcg tgagatgcca atcgtctcaa
    11161 atccgtgccc gtcaggtaat gcgtatcatc acagcagtga gcgatttttt cgtgggccag
    11221 cgttgctggc ttcatcgctt ttccgggcgc gtaagtgctc gccctgccca ggtactctgt
    11281 ttgcctgatt atccttatgc tgtcggatcc gctcggagtc gaaccctcca gggaggcacc
    11341 gctgtgcgca ttcgattcag aaggcctcga aatgacgagg taaatatctc ctaatcgggc
    11401 gcccctgcca ttccaggtac gggccatgga cgggcccctg tccgaattgg cctgaccatc
    11461 atagcgtgct tccctcctga cggcgcaacc ccatcgccct cacgatgtaa aggaaagtcg
    11521 tgaccgctgt ggggcggatc cctcgaatgc gcgttggtcg tctgttcctc gccccgtgaa
    11581 tgagcgcatt acggtgtgga cagcgagggt atgctgacga cggtccgaaa tcgtcgaagg
    11641 caatgcgggt gaagaagacg cgaaagcgct gatgtcctca gtgcgcccga ggatcggggc
    11701 ccctcagggc cacccgaaag cgtggcggct gagcagaccg atgctgaagc tcgccccatt
    11761 cgcgagcagg gaccagagga gcgcgcgctc cagacgaaac ccgaagcgga gatagaccgc
    11821 ctctgccacg acggcgaagg cctccgcgac ggccaccatg acccagtaat tgcccggcaa
    11881 cagctcgggc atcacgaacc agacgatcgg atgcgtgagc gcgctcgctc cgaacgcagg
    11941 cccccacccc gtcctggcgc accgagcata gatgggcatc tccacgcact gggtgaagag
    12001 gaaagcggag agccaggcag tgaacatctc ctgcccgggc tcacccggag agcggctggc
    12061 gagcgctcgg gcgtcggttc ttgtcgatga tggcgtacag gatgagcacg taagccagga
    12121 ggcggagcag gtacaggtag tggagatggt catccgccac ctggacggcg tggacggcga
    12181 tcctgcccag cgccagcaac cagaatgcgg ccgagaagat gaagaagagc cgatcgttcg
    12241 tctgcctcca gaaccggagg aagaacatgg ccaccaccgc gtagcccagc gtggatgcgc
    12301 cggagatgta ctcgttcacg gctcccacct cgcgacgttc atgcgctcac ggttctcctc
    12361 gacgctcgcg cgtgccctcg cgcatgtccc agagcagccc atagagaagc aggagcaacc
    12421 cgagcagcgc gaaggcgttc cgcggcatgg ccaggctgat ccgagtgggc aaaagaacga
    12481 gatcgacgaa tagaaggatg ttgttgacgg cgaaccctgc gaacccgagc ccgctccaca
    12541 ggagcaggcg cacccggttt tttgcatacc ctcgaaggag aagcaccatg catgcgatgc
    12601 tcgtcagcgc gcacagcagg taaaccgcgg ccgccatgtt cagtcgccgt ctttcttgcg
    12661 tatgaggaat gcgtcagaaa acgtctcgat gtctccgggc agctgcctcg catagatcat
    12721 gtcgatgatg gtcaggcggc gctccttgta ggctctggcc agctcgtcca cgacatgccg
    12781 cacctcgctc tcgggagcgt aatgatacca gaggtcgtca tcgacctcgc gcgtcgcgat
    12841 caggtcccga gccgcgaggt tcgcgagccg gtcccggatc gacatcatgc tcgagccgat
    12901 ctctcgcgcc acgtccgccg ggcgccactc tcgctctccg ctcttccgca acagcagcag
    12961 cacctcgagc agctcgatgg aggagatgtg catcgccacg aatcgttgca ctgcgtccgg
    13021 gactccactt gtcactacct tccctcacca ttggagattc cattcccgca tcccgtggtg
    13081 cgtgtcgtta tggaaccgtg aagcggggag ggcgcccgag cgcgcggatg atgccgctcc
    13141 caccggccag acaggcgatg gcggcgacga gctcggaagg ctcgatgggc ttggaagcat
    13201 gcatctggaa gcccgcggcc agcgcccggg cgtgatcctc tttccgggcg tagcccgtga
    13261 gcgccagggc gggcacatcg ccgccggcct tgggccccag gttgcggagc tggcggatca
    13321 gctcgaagcc gtcctcgttg ggcatcgcga catcggtcac gagcacgtgg ggccggcgcg
    13381 tcgagatgat ctggagcgcc tcgctcgccg aggccacggt cgtcacctcg gcccggtggc
    13441 ggcgcagcac ctcacccagc atctcgcggg tatcgtcctc gtcctcgacg acgacgacgt
    13501 agagcccctc gagggtattg gcgtcgtcct cgctcggctt cgccagcgcc gggtctgcgc
    13561 tccgcgccgt cgacgggatc gaaggcaagc gaacggtgaa cgtcgacccc tgtccctgac
    13621 cggcgctgtc ggccagcacc gaaccaccgt gcagctccac gatgtggcgc accagcgcca
    13681 ggccgatgcc cagaccgcct tgcgccctct tgctcgtgct gtccgcctgc cggaagcgct
    13741 cgaagacgaa cggcaagaag tccgggttga tcccttcgcc cgtgtcgtga atgaccagcg
    13801 tgacctcccc ctcgccgagg gacaggctga catcgacacc gcccccacgc ggcgtgaatt
    13861 tgatcgcatt ggacagcagg ttggaaatga cctgctggag ccgctccgaa tcgccctgga
    13921 tctcgcaccc atcgatctcg gctttgagcg tcaccccgcg cgcctccgcc gccgggcgga
    13981 gtgtatcgat cacggcctcg acgagcggac cgagctccac cgtcgcaacg gagagcttca
    14041 tcttgcccgt ggtgatccgg gagatgtcga gcaggtcctc gatcatccgg acctgcgcgt
    14101 tcacattgcg ctcgatcact tcgaaccccc gctcgaactt cgccggatcc atcgggctcg
    14161 tctgcaagag acgggtccag ccgaggatgg cgttcagcgg cgtgcgcagc tcgtgcgaga
    14221 gcgtcgccag aaactcgtcc ttcagccgat tggcctcgcg tgcctccagg ttcagaccgt
    14281 tctggagcgc gatcgatccg agctgcgcga gctggaccag aatggcctcg tcgtcctccg
    14341 tgaactcacc ctggaccctg tcggagagct ggatgaagcc catgttgcgg cccgtcacct
    14401 cggtgagcgg cgcggccagc accccgcgca ggggtggccc catgggctca tcgggctgcc
    14461 actcggggtg cgccttgagc tcggcctcgg tgagccggat ggggcgattg cgcgcgtaga
    14521 gcacatcgtg caggcgcgtg agccccgtcc ctggcgcccg tgtcgaccgg agcgccggcc
    14581 ggtagccacg aaacgccggg gcgagctcct cggccagaga gaccgccacg cgcggccgct
    14641 ccccggggtg cccgagcgtc gccaccgaga acgcctgctt cgcctccagg atgtcgcgcg
    14701 ccgactccgt gatcgccctc agcgtcgcgt ccagcgacag cgaggcgttg atggcgatcg
    14761 acgcgttggc cagcttgttg agctgcgccg cgcggcgctg gagcgcctcg gcttgccgct
    14821 tcacctccgc cgtcttcttg aacagctcca cgaagacgcc gaccttggtc ttcagcacct
    14881 ccggatccac cggcgccagg atgtagtcga cggcgcccag cgagtagctc ttcagcgcgt
    14941 tgggctcttc cccgaaggcg gtcacgaaga tgatcggcgt gtgacgcgac gtccgatgct
    15001 gccggatcag ctctgccgtc tcgaacccat ccatgcccgg catgttgatg tcgagcagga
    15061 tcaccgcgaa ctcctgctgg agcacatggc ggagcgcgtc gcgccccgac atggcccgca
    15121 cgatgttctg ccccagctct tcgaggatcg tctccagagc gagcagcttg tccggcttgt
    15181 catccacgat gaggatgtcc accggcccgg ccccgctcgg ggcggaagac tggggcaccc
    15241 tcgtgccgct gggtcgaccg ctcggcgtgc tcatcggtgc aaccacaacc tgagggcggc
    15301 gagcagctgc tcggtgtcca ccggcttgga gatgtagtcg ttcgcgccgg cctccaggca
    15361 cttctctcga tcgcccttca tggccttggc cgtcagcgcg atgatcggca gcgcgtggaa
    15421 cctgggctcc gcgcggatcg cgcgcatcgt gtcgtagccg tccatctccg gcatcatgat
    15481 gtccatgagc acgacgtcga catcgggtgt ctggccgagc acctcgatcg ccgccttccc
    15541 cgtctccgca tagactgtct tcatctgatg cgcctccagc agcgtggtca tggcgaagat
    15601 gttgcggatg tcgtcatcga cgatgagcac cttctttccc acgataacct tgttcgactg
    15661 atgaagctct gcgagcagct cttgcttgga cccgggtagc gccggcagcg ggagatgcaa
    15721 gaagagcgac acctcgtcga gcagccgctc tggtgagcgg acgtgcttca agacgagcga
    15781 ctgcccgagc cgcgcgatcc gctcttcatc gctgagcgac agctccccgg gcgtgtacag
    15841 gacgaggggc cgctccttct gcccttctcg ccgagccatc cgatcgaaca gctcgaacgc
    15901 gcgcatgtcc gacagatcca gccgggtgac caccacctcg ggtgacgcgc tctccagcgc
    15961 gttcatcgcg ctgccacccg tctccacgtg ctgcacctcg accccgtcga tcccgagcag
    16021 cttcgtcagg gccgcgcgct ccccctcgtc gggctccacg agcaacaccc tgcgcttcgg
    16081 cgccttcatg aactgaatga gctgctcgaa ggcggcgtcc agctcgtcgc gcgccttgag
    16141 cggcttgtgg agcaccccac gcgcgcccag ccggagcgcc cgctcccgat cctcgtccgt
    16201 cgtgatcacg tggacgggga tgtgccgcgt ctccagatcg tgcttcatcc tggccagcac
    16261 gcgccacccg tccacatcgg gcaagttcag gtccagcgtg accgcccccg gacgccgctc
    16321 ccgggcgagc gccagcgccg tcgagccccg gtacgccagc agcaccttga gcccgtgctc
    16381 tcgcgcgacg tccatcagat accgcgcgaa gttcacgtcg ttctcgacga tcagcaccac
    16441 ctgatccccg gcctcgatcg acgtcctgtc atcgatgatc tggttgatca ggtgcgacgg
    16501 cggctccggc ggcgcccgga gggcgagctc tgcgctgacc agcggttgag acggtctcga
    16561 ctcggagacc ggctccttcc ccttgcgccc cttcgccggc gcatagctga gtggcagcag
    16621 cagcgtgaac gtgctgcctt ccccgggcac gctccgcagc ttcagctccc cgccgagcag
    16681 ccgcgcaatc tcgcggctga tcgccagccc cagccccgtc cccccgtact tcctgctcgt
    16741 ggagccgtcc gcctgctgga acgcctcgaa gatgatctgc tgcttgtccg gctggatccc
    16801 gatccccgtg tccgtgaccg ccatcgagat cgctgccccc gcgcgctgga gcgtctcgtt
    16861 ctccggatcc cagcccgagc ggatcatgcc gacctggaac gccaccttgc ccttgtccgt
    16921 gaacttgaac gcattcgaca gcaggttctt gatcacctgc tggacccgct tcgcgtccgt
    16981 gtagaccgcc cgcggcaggt tgccgtcgaa ctccagctcg aagcccagcc gcctcgactc
    17041 cgccacgtgg cggaacgccc gctcgacata gtcgtgcagg tccatgaacg acacctccgt
    17101 gacgtccacc accaccgtgc ccgactcgat cttcgacaga tcgaggatgt cgttgatcag
    17161 cgccagcagc tcggcccctg acgagtggat cgtccgcgcg aagtcgacct gccgcccgga
    17221 caggttgcct tccatgttct tcgagagctg gtccgagaga atcagcaagc tgttcagcgg
    17281 cgtccgcagc tcgtgcgaca tgttcgccag gaactcggac ttgtacttcg acgtcagcgc
    17341 cagctggtgc gccttctcct cgagcgcctg acgcgcgtgc tcgacctcct ggttcttccg
    17401 ctccacctcc gcgttctgct ccgcgagcag ccgcgccttc tctcccagct ccgcgttcgt
    17461 ctgctgcagc tcctcctgct ggctctgcag ctcccgggcg agggactgcg actgcttcag
    17521 cagatcctcc gtccgcatgt tcgcctcgat cgtgttcagc acgatcccga tcgactccgt
    17581 gagctggtcg aggaacgcct ggtgcgtcgg gctgaagcgc tcgaaggacg ccagctcgat
    17641 caccgccttc acctgcccct cgaacagcac gggcatcacg atgatgttga ccggcggcgc
    17701 ctcccccagc ccgctcgtga tcgtgatgta gtccggcggc gcgttcacca gcaggatctt
    17761 ctccttctcc agcgcgcact gcccgaccag cccctcgccc agcttgaact ggttgtcgac
    17821 gttcttccgc tgcttgtacg cgtagctcgc gagcagcttc aggcgcggct cctccttcgt
    17881 cgtgtccatc gtgtagaaca cgccctgctg cgcgccgacc acgggtgcca gctccgacag
    17941 gatcagccgc cccacggtga gcagatcctt ctgcccctga agcatgcgcg agaacttcgc
    18001 gaggttggtc ttcaaccaat cctgctcgct gttcttcagc gtcgtgtcct tcaggttgcg
    18061 gatcatctcg ttgatgttgt ctttgagcga cgccacctcg ccctgcgctt ccacgcggat
    18121 cgagcgggtc agatcgccct tcgtcaccgc cgtggccacc tcggcgatgg cgcgcacctg
    18181 cgtcgtcagg ttcgccgcga gctggttcac gttgtcggtg aggtccttcc acgttcccgc
    18241 cgcaccgggc acgctcgcct gaccgccgag cttcccctcg acaccgacct cgcgcgccac
    18301 cgtggtcacc tgatccgcga acgtcgccag cgtgtcgatc atcccgttga tcgtgtccgc
    18361 cagcgccgcg atctccccct tcgcatccac cgccagcttc tgcttcaggt caccgttggc
    18421 gaccgccgtc acgaccttgg cgatgccgcg cacctggttc gtcaggttgc cacccatcga
    18481 attcacggag tcggtcaggt ccttccaggt cccagcgacc cccggcacgc tggcctgccc
    18541 accgagcttc ccttcggtgc cgacctcccg cgccacgcgc gtcacctccg atgcgaacgc
    18601 gctgagctga tccaccatcg tgttgatggt gttcttcagc tccaggatct ccccccgcac
    18661 atccacggtg atcttcttcg agaggtcacc gtttgccacg gccgtcgtca ccgccgcgat
    18721 gttgcgcacc tgggccgtca ggttcgacgc catcgagttc acggagtcgg tgaggtcctt
    18781 ccacgtcccc gcgaccccgg gcacgctggc ctgcccaccg agcttccctt cggtgccgac
    18841 ctcccgcgcc acacgggtca cctccgacgc gaacgaccgg agctgatcca ccatcgtgtt
    18901 gatggtgtcc ttcagctcca ggatctcccc ccgcacatcc acggtgatct tcttcgaaag
    18961 gtcaccgttg gcgaccgccg tcgtcaccgc ggcgatgttg cgcacctggg ccgtcaggtt
    19021 ccccgccatc gagttcacgg agtcggtcag gtccttccag gtccctgcga cccccggcac
    19081 gctggcctgc ccaccgagct tcccttcggt gccgacctcc cgcgccacgc gcgtcacctc
    19141 cgacgcgaag gcgctgagct gatccaccat cgtgttgatg gtgttcttca gctccaggat
    19201 ctcccccttc acgtcgacgg tgctcttccg cgacaggtct ccccgcgcga ccgccgtcgt
    19261 cacctcggcg atgttgcgca cctgcgccgt caagttcgac gccatcgagt tcacggagtc
    19321 ggtcaggtcc ttccacgtcc cggcgacccc tggcacgctg gcctgcccac cgagctttcc
    19381 ttcggtgccg acctcccgcg ccacgcgcgt cacctccgac gcgaacgacc ggagctgctc
    19441 caccatcgtg ttgatggtgt tcttcagctc catgatctcg cccttggcat cgacggtgat
    19501 cttcttcgag agatccccgt tcgccacggc cgtcgtcacc gcggcgatgt tgcgcacctg
    19561 ggccgtcagg ttcgacgcca tcgagttcac ggagtcggtc aggtccttcc aggtccccgc
    19621 gacccccttc acctccgcct gcccacccag ctccccttcg gtaccgacct cccgcgccac
    19681 gcgcgtcacc tcggctgcga acaggctgag ctgatccacc atcgtgttga tgacgttctt
    19741 gatctgcagg atctcgccac gcacatcgac ggtgatcttc tgcgtcagat ccccgttcgc
    19801 gatggccgtt gccaccttcg acacgtcacg gagctgcacc gtcaggttgg accccatcga
    19861 gttcacggag tcggtcaggt ccttccacgt ccccgcgacc cccttcacct ccgcctgccc
    19921 accgagcttt ccttcggtgc cgacctcccg cgccacacgg gtcacctccg ccgcgaagga
    19981 gctgagctga tccaccatcg tgttgacgac gttcttgatc tgcagaatct cgccacgcac
    20041 atcgacggtg atcttctgcg tcagatcccc gtttgcgatg gccgtcgcca ccttcgacac
    20101 gtcacggagc tgcaccgtca ggttggaccc catcgagttc acggagtcgg tcaggtcctt
    20161 ccacgtcccg gcgacccccc ggacctcggc ctgcccaccg agctttcctt cggtgccgac
    20221 ctcccgcgcc acacgggtca cctccgccgc gaaggagttc agctgatcca ccatcgtgtt
    20281 gatggtgttc ttcagctcca ggatctcccc tttgacgtcg acggtgatct tctgcgtcag
    20341 atccccccgc gcgaccgccg tcgtcaccgc ggcgatgttg cgcacctggg ccgtcaggtt
    20401 cgacgccatc gaattcacgg agtcggtcag atccttccac gtcccggcga ccccccggac
    20461 ctcggcctgc ccaccgagct ttccttcggt gccgacctcc cgcgccacgc gcgtcacctc
    20521 cgacgcgaag gagttcagct gatccaccat cgtgttgatg gtgttcttca gctccaggat
    20581 ctccccccgc acatccacgg tgatcttctt cgaaagatca ccattcgcga ccgccgtcgt
    20641 caccgccgcg atgttgcgca cctgcgacgt caggttgccg gccatcgaat tcacgttgtc
    20701 cgtcaggtcc ttccaggtcc cggcgactcc aggcacgctc gcctgcccac cgagcttccc
    20761 ttccgtaccg acctcgcgcg ccacgcgcgt cacctccgac gcgaacgacc ggagctgatc
    20821 caccatcgtg ttgatggtgt ccttcagctc caggatctcc ccccgcacat ccacggtgat
    20881 cttcttcgac agatccccat tggccacggc cgtcgtcacc gtggcgatgt tgcgcacctg
    20941 cgccgtcaag ttcgacgcca tcgagttcac ggagtcgg
//
