LOCUS       NZ_KQ257877            25149 bp    DNA     linear   CON 02-JAN-2025
DEFINITION  Streptomyces stelliscabiei strain P3825 scf_652_123.1, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ257877
VERSION     NZ_KQ257877.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces stelliscabiei
  ORGANISM  Streptomyces stelliscabiei
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 158285)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Genome sequencing of plant-pathogenic Streptomyces species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 158285)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JUL-2014) Biosciences, University of Exeter, Geoffrey
            Pope Building, Stocker Road, Exeter, Devon EX4 4QD, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001189035.1-RS_2025_01_02
            Annotation Date                   :: 01/02/2025 01:49:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,536
            CDSs (total)                      :: 9,455
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 81
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 482
            CDSs (without protein)            :: 482
            Pseudo Genes (ambiguous residues) :: 0 of 482
            Pseudo Genes (frameshifted)       :: 129 of 482
            Pseudo Genes (incomplete)         :: 407 of 482
            Pseudo Genes (internal stop)      :: 20 of 482
            Pseudo Genes (multiple problems)  :: 69 of 482
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:19:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 123635
            Orig. end                         :: 148784
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ257877.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25149
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="2"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25149
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25149
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15149](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15149)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    241..255
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.19"
                     /tool="antismash"
     gene            535..1869
                     /locus_tag="IQ64_RS44765"
                     /old_locus_tag="IQ64_47805"
     CDS             535..1869
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005350.1"
                     /locus_tag="IQ64_RS44765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47805"
                     /product="ricin-type beta-trefoil lectin domain protein"
                     /protein_id="WP_192781637.1"
                     /transl_table=11
                     /translation="MRQGNNHHRWRAPIAVAIALLLAAAGISGIGLTSAAAAEAPSAAP
                     SAGCGKPPTLSSGPRSIQSSGRTRNYILRVPATYDNNRPYRVVFGFHWNGGTANDVDSG
                     GTSGYPWSYYGLRAISNDSAIFVAPQGLGNGWANSNGEDLTFVDDMIRQIDAGLCVDTN
                     QRFAGGFSYGGGMSFALACARPTVFRAVAVYAGGQLSGCNGGTQPVAYIGLHGLRDPVL
                     PIATGRSLRDRFVRNNGCTAQNPPEPARGSLTHVVTTYSGCRAGYPVAWAAFDAGHTPG
                     PVDGSPGDYEPGERSWTRAVVWNFFTQLDGADPTPPNPATFRLRNEGSGRCLDVNGASG
                     TNGTPMIIWDCHGNANQQFTQNGQALQVLGKCLNVPTDAAAGTRVQIQDCNGGANQQWA
                     LNSNGTIRNAQSGLCLDVNGASTANGSAVVVWSCHDGANQRWARA"
     misc_feature    595..597
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1928..3640)
                     /locus_tag="IQ64_RS44770"
                     /old_locus_tag="IQ64_47810"
     CDS             complement(1928..3640)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996110.1"
                     /locus_tag="IQ64_RS44770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47810"
                     /product="lectin"
                     /protein_id="WP_046914076.1"
                     /transl_table=11
                     /translation="MRRRPRTLLGGAATALATLVLLGQPHPVHAADTAYDVLVFSRTAG
                     FRHDSIPAGIQAIRELGTANNFTVTATEDGGQFTTGNLSRYEAVVFLNTTGDVLNDTQQ
                     SAFQSYIGSGGGFVGVHSAADTEYNWPFYGDLVGAYFASHPAVQRADVKVEGRAHAATA
                     HLPQTWTRTDEWYNFRTNPRTTARVLTTLDESSYSGGSMGADHPHSWCKTHSGGRAFYT
                     GGGHSQAAYAEPAFRAHLLGGFRYAAGRTKADCRPETGYTTLYNGSTTGWSQAGPGGFT
                     NTDATLASHGGMGMLWYSAKQFTNYSLKLDWKMSGDDNSGVVVGFPPTNDPQSALDNGY
                     EVQIDATDAPDRTTGSIYAVKAPDTAARDAALDPPGEWNTFEVLVEGERLQVWLNGVKI
                     NDFTDTNPARSLAGHVGIQNHGTGDDVSFRNVRIKDLGGSPPPTPGAGPIVGGAGKCLD
                     IRDGSSADGAAVQISSCTGAARQQWTVAPGSTVKALGKCLDVSGGSTADGARVVLWSCN
                     GGANQNWQASTDGSLRNPRSGKCLDVSGANSSDGTLVNLWSCHGGANQKWTLP"
     CDS             complement(3670..>3793)
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988451.1"
                     /locus_tag="IQ64_RS47395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_159392255.1"
                     /transl_table=11
                     /translation="GSLRNPRSGKCLDVSGANSSDGTLVNLWTCHGGTNQKWTLP"
     gene            complement(3670..>3797)
                     /locus_tag="IQ64_RS47395"
     assembly_gap    3798..3807
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<3808..6307)
                     /locus_tag="IQ64_RS44775"
                     /old_locus_tag="IQ64_47820"
     CDS             complement(<3808..6307)
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037552.1"
                     /locus_tag="IQ64_RS44775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47820"
                     /product="carbohydrate-binding protein"
                     /protein_id="WP_078907696.1"
                     /transl_table=11
                     /translation="MFMKINRAAVARWPAIGSTLLLVAAALVANLSGATPASAHPINAA
                     DFQQVQLARGVPEVGEPMSLAVLADRSVLHTARNGTVRRTDANGTTTVIGTIPVYAHDE
                     DGLQGIGIDPRFATNRHIYLYYAPPLSTPGGDAPTTGGNWSTWQGVNRLSRFTLNGDFT
                     INQSSKVDVLDVPADRGICCHAGGDIDFDAAGNLYLSTGDDTNPFESAGYAPLDERTNR
                     NPAFDAQRTAANTNDLRGKILRIKVKDDGSYSIPEGNMFAPGTARTRPEIYAMGLRNPF
                     RMSVDKATGIVYVGDYGPDAGATSARGPQGQVEFNRVTGPGFYGWPYCNGTNTNAETFA
                     EWDFATNTAGAKYNCSGGATNNSFRNTGLSTLPPAKAAWIRYGGDAGSPPAFGGGSESP
                     MAGPVYRYDPDLNSPTKFPQSFDGQFFATEFGRGWIKPIHLNADGSPGTIDSFPWTGKQ
                     VIDSAFGPDGSYYVLDYGAGLYQGDQYSALYRFDHVGGGNRAPTAVAGANRTSGAAPLT
                     VTFSSAGSSDPDGGALTYAWSFGDGTGSTAANPTKTYDTNGNYTATLTVRDPQGATGTA
                     DVRITVGNTAPTVTVDRPAAGEIFAFGDTVPFAITVTDPEDGTVDCAKVKMTYIVGHDS
                     HGHPVTSKTGCSGTITIPVDGEHDDAANIFGVFDAEYTDNAGLTTHTQHILQPKHRQAE
                     HHKTSSGISILDKSTAEGGKSVGDIENGDWIAFEPYRLSNATSFSARVSSAGAGGTLQV
                     RAGSPTGTVLGSATVPVTGSWTNFTTVNGSISGAPAGTTTLYLTFAGGSGYLFDVDAFT
                     FDTGGGPSAGPIVGGAGKCLD"
     misc_feature    6478..6498
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.67"
                     /tool="antismash"
     misc_feature    complement(6488..6502)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            <6730..>6855
                     /locus_tag="IQ64_RS48370"
                     /pseudo=""
     CDS             6730..>6855
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142650.1"
                     /locus_tag="IQ64_RS48370"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="ferrochelatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRRTAVERGDHVAPCALGALGASHHLCPAGCCPARAPRPAAA"
     gene            complement(7102..8490)
                     /locus_tag="IQ64_RS44780"
                     /old_locus_tag="IQ64_47830"
     CDS             complement(7102..8490)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004952186.1"
                     /locus_tag="IQ64_RS44780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47830"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_046914049.1"
                     /transl_table=11
                     /translation="MSYNVRFWDIRERLDRRKPFMVRWTVNGREKSESFMTVGLAESRR
                     AKLMTAAREGEPFDQHTGLPASELRAIKQRTTWYDLAHEYLDQRWDRTPGNTRRTLADA
                     FATITPALVRPGVTYPEPRVLRRALYSWAFNKKAWEKEPAEEWRQALDWMKRNSLPVSA
                     LAEADVLRRALDALCLKLDGKEAAAKTARRKRAAFNEVLNVAVEKGYFTENPLNGLRWK
                     APVVNEEVDPAAVPNPAQVARLLTAVARQRGRGPHLEAFFGCMYYAAMRPAEVIHLRLE
                     QCHLPDSGWGMLNLSGGVVTSGKEWTDSGSVHEVHSLKRRAATATRPVPVPPQFVRMLR
                     SHIERFGVAPDGRLFRNQAGNYVDAAAYGTTWARARKYVLTRTELASKLAKRPYDLRHA
                     GISFWLYSGVDPAECARRAGQSIEVLFRHYAKFLDGVREQANRLIEQSMQEWDRVSQGP
                     ESEG"
     gene            complement(8487..8684)
                     /locus_tag="IQ64_RS52870"
     CDS             complement(8487..8684)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979375.1"
                     /locus_tag="IQ64_RS52870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_078907685.1"
                     /transl_table=11
                     /translation="MARPPVLKLAEVLAEIRMSPSAFYRMRARGEAPRMIKLPNGELRC
                     RRPDLDAWWDKCERDSDTWR"
     misc_feature    8684..8694
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(8937..8954)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.77"
                     /tool="antismash"
     CDS             complement(10001..>10890)
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319709.1"
                     /locus_tag="IQ64_RS47405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_208613840.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.1e-28, bitscore:
                     94.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ADAASRAGTSPARLADAVERYRAAGRTALDASPEGWHQVNIEFAD
                     YPTAEQTFRAYLLPSLRGAPVGAWWFLRKYPCWRLRVHPSPGTPAEEVIAHVTEALDSA
                     VSWSVVKNWCPYLYEPESVAFGGPDGMMITHRVFHTDSMGVLDYHQHAAGETDGVLDAK
                     ATSLLVTTLFLRAAGLEWGEQGDVWGQIEAKRPLPEDVPADRVSAMADTMRQLLLLDAG
                     PAINDGPLASLQSWVTGMEHGGRALADIARDGRLGLGLRSVVSRHVLFHWNRMGFTARQ
                     QAIWSRAAREAVLGC"
     gene            complement(10001..>10892)
                     /locus_tag="IQ64_RS47405"
     assembly_gap    10893..10907
                     /estimated_length=15
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(10984..12129)
                     /locus_tag="IQ64_RS44790"
                     /old_locus_tag="IQ64_47845"
     CDS             complement(10984..12129)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447324.1"
                     /locus_tag="IQ64_RS44790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47845"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_046914048.1"
                     /sec_met_domain="LANC_like (E-value: 7.4e-41, bitscore:
                     133.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAPPITDTTIATRQSLARGPLGSALLHIERAHRGLTPWRDVHQ
                     QLAGIRPLIDGDTAGLFLGAPAMTYVLHLAAADSDRYAGALHTLDRIVAAHTRRRLDAA
                     HARIDQGGYTAFAEYDLFRGLAGLGSLLLRRQPEGPELRGVLEYLVRLTQPIAGANGEQ
                     LPGWWVAHSPASKTITQGGHANAGLAHGISGPLALLALAKRRGITVDGHDTAMAGICRW
                     LDGIRQSDHRGTRWPRWISEVGPSPVLPATPSWCYGTPGLARAQQLAAVALGDEDRKRM
                     AERALLYCLDDAHQLDKLSNRGLCHGVGGVLRTVQRFAEDAETPHAFTVRLPLLRQRFL
                     AADLPEGAGFLEGEAGAVLAFQSAEQEAGPVTDWDACLLLS"
     gene            complement(12126..15149)
                     /locus_tag="IQ64_RS44795"
                     /old_locus_tag="IQ64_47850"
     CDS             complement(12126..15149)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319705.1"
                     /locus_tag="IQ64_RS44795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47850"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_046914047.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.2e-183,
                     bitscore: 603.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 7.5e-24,
                     bitscore: 77.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.4e-34, bitscore:
                     113.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYHTVDAGMIRASVFPMAAPLPPWPTLVGEESADTDLWREWITQV
                     WADDIRAAAIEFAAPRLADSIREVAAGQCQRSRAVRRTAISLARYVLRMQYRATPFGLF
                     AGPAPIRIGAASHVDWGTEHRAFVHADAEWLNDVITTLERDPDVLRNVPVVANSRCIVR
                     GSRIALLFQPGAEGPTETTLRRTPAVETVLALARTPITVSTLAAKLRSDYPDTPDEQIH
                     AMLHSLVEHRVLLTSLHAPMTCGDALGHLVEQLDTTSVAPAKADELRQARTLLTRHDEA
                     PQRAQRTLRAKATAKMNALTGITDRSLVVNLRPDCDIVLPDTVTREAEHALQVITRLTP
                     FPNGSAAWQDYRTRFLERYSMGTIVPLRDLTDPDTGLGFPAGYRGTVLKRPVLATTLRD
                     EHLLTLAQDAALNDQRTVDLTEADIEALALGRPTQVPAHVALSFTVLARSLNDVEDGGF
                     ALVIKGLSLSVGITTGRFLTMLEAADFDRMAAAYSTLPTLTAGADLGQVSSPPLRVRTR
                     NVGRAPALMPNVLSVGEYNPDATLDVDHLGVVADARRLYLVSLSTGQVIEPMVMNAVEL
                     TNATHPLVRFVSELHRSHTATLIPFAWGAAARLPFLPEVRVGRTILSPASWRLRTADLV
                     DGGNWASALSDWRARRRVPRTVYVGNDDQRLRLDLDLPAHHQLLRAELDRHPTVMLREA
                     PPEDAFGWLGRAHEVTVPFISDQRPAPAAVRRTAAVVGRDSGRLPGASPWTYLKLYGNA
                     ARVPELLTAHVPLLLGEVEPLEWWFIRYADPDSHVRLRLRLPSPDAFGNTAQRVATWAA
                     ELRAEGLLQRVRWDTDEPETGRYGTGAALEAAERFFAADSDAALTQIALPLPDSHRQAV
                     TAASFVDIATAFLGTPEAGRAWLTANFPQSDGATALPRDVQALVVRLTSAEHHCPIQEI
                     QAGDAVAQAWATRQAALLAYRTVLEATGIDPASVLGSLLHMHHNRATGIAPDAEATCRR
                     LARAAALSWTIRTEGAKR"
     misc_feature    complement(14397..14399)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(14427..14690)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IQ64_RS44795_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="1.30E-24"
                     /identifier="RREFam001.1"
                     /label="IQ64_RS44795"
                     /locus_tag="IQ64_RS44795"
                     /protein_end="241"
                     /protein_start="153"
                     /score="77.7"
                     /tool="antismash"
                     /translation="VVANSRCIVRGSRIALLFQPGAEGPTETTLRRTPAVETVLALART
                     PITVSTLAAKLRSDYPDTPDEQIHAMLHSLVEHRVLLTSLHAP"
     gene            complement(15221..15409)
                     /locus_tag="IQ64_RS44800"
     CDS             complement(15221..15409)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="IQ64_RS44800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_046914046.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 5e-15, bitscore:
                     48.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPRSTGTTLKSGTDFAMHGGSDFDLSIETVASAPVIGALLNDTG
                     DGCGQTCQSACSNSTCE"
     gene            complement(15474..16700)
                     /gene="fxlM"
                     /locus_tag="IQ64_RS44805"
                     /old_locus_tag="IQ64_47860"
     CDS             complement(15474..16700)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009334866.1"
                     /locus_tag="IQ64_RS44805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47860"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_046914045.1"
                     /sec_met_domain="PCMT (E-value: 2.5e-43, bitscore: 141.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTENSDKSPASEQELRDRMVKQLIELGAARSPRVVAAFRSVPRHL
                     ATPDEDMAKVYEPETATITKTDATGTQVSSVSAPRIQAMQIEQADIRPGMKVLEIGSGG
                     VNAAYLAELVGDGGHVVTLDIDPDITRRAKDFLKATGYSNVTVITADGEYGAPDHQPYD
                     RIIITVQAADIPPAWIHQLAEGGRLVVPLRMRGMTRTVAFVRDGQHLVSDGVELCGFVP
                     MQGVGENRMRLAVLHDVEGEEIALRLDDHPEPDAEALRAALRSPRAEEWSGVTLAGDES
                     KEQLDLWLASALHNLPLMAATPAARQRGLVAARTPLGVPTLVDGDSFAYRTVRATEDPD
                     RFELGAAGHGPQGKEVAERLVEEFQVWNGEHRRQRAHIEVHPAGTPDEQLPVGRVIDRR
                     HTRVTISWS"
     gene            complement(17348..17896)
                     /locus_tag="IQ64_RS44810"
                     /old_locus_tag="IQ64_47865"
     CDS             complement(17348..17896)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039764.4"
                     /locus_tag="IQ64_RS44810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47865"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_046914044.1"
                     /transl_table=11
                     /translation="MTALNERAPVDAHTIRETYTVGLDVWGTCPPELVKLKTLLGRLRG
                     HVQLLVPEVTAIAARMRGEMRHAAVYVIVRAHRLLEEGAGKSQVAKACHAQDLAVISRA
                     LLTLFENPGPLGPSTGTSDIEEAIRGRICGACSQLIASGESYERVLFASEASGGIHGYR
                     HTDSCVVVAEERRAQLRAI"
     gene            complement(17893..18393)
                     /locus_tag="IQ64_RS44815"
     CDS             complement(17893..18393)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="IQ64_RS44815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_050399737.1"
                     /transl_table=11
                     /translation="MADLLELPAVPATGVRATTRSKSGHLEIDLDVTSEAVPIIRTVVR
                     AHLELWGLSGLIDSAALTVTELLTNVLRHTDPLPGTGTRGARLTVTRLTGILNVCVRDF
                     DPALPKLSYDAADAECGRGLLLVASFADDCGCSEFTGGKDVWANFLVRGDEASDSGRAR
                     GAS"
     gene            18555..19955
                     /locus_tag="IQ64_RS44820"
                     /old_locus_tag="IQ64_47875"
     CDS             18555..19955
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378988.1"
                     /locus_tag="IQ64_RS44820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47875"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_078907689.1"
                     /transl_table=11
                     /translation="MPQPEKELNPDASPQAWFGAELRHWRKRQPGLRAAQLGPMVQVSP
                     DVISKIEKGSYRCRRDLAERLDDVLETGGVLTRAWGMVFGDADKRRRDADSARRGPVEG
                     TIQVHQGRMLGTDPSAPLSESLTSVDRRAFLAATSLAAFAPIELARLVAPTAPPELPKR
                     IRPTELDQLRLIADSIHRWDNAQGGGGLVGDFASRSMEWAVRLLFVACPEQLRPDLLSS
                     IARLGIVVGATHFDAYAHGEARVAFKVASECAEEAGDWWLRAKTFSFLSRQATWLGDPD
                     EGLTYAEKGLVRADRLTPTIQAMMHSARARAFGKMNDVQGTMAAVGAADDAFARSNPAK
                     DPAWMHYYDEAQHHGDTAHALFDLSIHAEQDPGRAAQRFTTAVVGHGDDYARSRGISRT
                     KLASLLMAKGDPMQAITIGHQALNDVGRLTSRRAADDLRELRRFAGQHRTLEEAAQLRQ
                     RITATLQA"
     gene            19952..20833
                     /locus_tag="IQ64_RS44825"
                     /old_locus_tag="IQ64_47880"
     CDS             19952..20833
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031333.1"
                     /locus_tag="IQ64_RS44825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47880"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_078907690.1"
                     /sec_met_domain="APH (E-value: 2.1e-22, bitscore: 73.6,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNSVAPARAVLEEACARASFDPAGAEPVRLAENEIWRLPDQVIV
                     RIARAGQWDAAVREVRVARWLADNELPAVRALPVEQPVEAAGRPATFWAELPRHEIGTV
                     RDVVVLLKQLHPLPLPGFPLDRLDPFVRVAERIEAATSLSEDDRAWLRHRHAELREWWE
                     HRPMGLPECLVHGDAWVGNVARTAAGPILMDFERASIGPPEWDLVSTAVKLTTTGTVTE
                     SEYAEFCQAYGRDVTEWEGYELLAGARELRMTTYAAQHAATRPEWQAEAQYRVDCLRGR
                     AEARPWRWKGIM"
     gene            complement(20941..22350)
                     /locus_tag="IQ64_RS44830"
                     /old_locus_tag="IQ64_47885"
     CDS             complement(20941..22350)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000002.1"
                     /locus_tag="IQ64_RS44830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47885"
                     /product="amidase family protein"
                     /protein_id="WP_050399738.1"
                     /transl_table=11
                     /translation="MNTSYPDLPAHAQLNALQQGAISNRDLLDLHLERIQASTLNAVIT
                     LDIEAAQRAADASDTRRTRGEPVGLLDGLPLTIKDSFETAHLRTTCGSEDLRHHIPEQD
                     ADAVARLRHAGAVIMGKTNVPAYCQDLHTDNTLFGTTHNPHDPTRTPGGSSGGAAAAIA
                     AALTPLELGSDLAGSLRLPAHYCGVYALRPTQGLVSARGHIPRPPGWLTTSDMLTPGPL
                     ARHPRDLALMLTALTTPTPDEHTPWRLSLPEPPRQLDDFRIAIWPSDPGCPVDDATAAT
                     LELLTRQLGATGAHITATRGPVGFTDASQLFEQLLHANASLAGSDDAFTADLTSARQLC
                     EDDTSLRATALRHRTQPHRSWLIAREERARQRAAWTAFFEHHEVLLTPAAPTPAIPNGS
                     RTLQINGHERSFFDQTGWANLISHIGLPAVIVPVGTNDQGLPIAVQLIGAPYADRTLLA
                     LAMHLESFDLL"
     gene            complement(22347..23318)
                     /locus_tag="IQ64_RS44835"
     CDS             complement(22347..23318)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042915.1"
                     /locus_tag="IQ64_RS44835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MAB_1171c family putative transporter"
                     /protein_id="WP_159026162.1"
                     /transl_table=11
                     /translation="MPADRSLPHVLSHWSSAADRARQMSRYWLGSGAAVITALFVLFFL
                     LTPAVQRPTDFTLYYAHDHIYAAYLTVYISAYTLAEVYLSVASWRLASRSPRTAVRVGL
                     RTVAVGAAVTLGYSAVRIGNVTAAALGTSLTGWEDFAWICGDLGTILTLVGWLIPTLTA
                     QTRHATYQWDLRRAHRQLHPLWLVFYRAVPEIALTPNDSTADDRSHTRGIPFQVYRRVV
                     EIRDGQTAVRPYLDHHIRQASEERHRAAGLTGDELHAAVTADQIRAALTAHTEGTLPAQ
                     PTDFADQNIESWHPIEDLPALRAIARHFARHDQPTAPEAVST"
     gene            complement(23285..23932)
                     /locus_tag="IQ64_RS53845"
     CDS             complement(23285..23932)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018259.5"
                     /locus_tag="IQ64_RS53845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TniQ family protein"
                     /protein_id="WP_078907691.1"
                     /transl_table=11
                     /translation="MNNVKWPTGAGVHAFVRRGRRKSLRRTRKWEGAALAAVHVLARHT
                     IPQVPARSPVAVPRARRLPVVPKPVSGEAFSSWVDRVAGTLSAPPGRAAHALGLECSEG
                     AAITRPVFFGVILTPESLSGLRDATGLPVRTLQAMQLARYDGTALDFAGLEPSDRTSMR
                     LVALREWMLTTSSRACPCCLAERPVWPLWWRLGIAAVCPVHRCLLIDLCPTS"
     misc_feature    complement(24019..24034)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.09"
                     /tool="antismash"
     misc_feature    complement(24063..24074)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.29"
                     /tool="antismash"
     gene            24181..>24293
                     /locus_tag="IQ64_RS52875"
                     /pseudo=""
     CDS             24181..>24293
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014043973.1"
                     /locus_tag="IQ64_RS52875"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVPYSAALDLPHALAEWVTVTMLIVTREGDRRCKLPP"
     misc_feature    complement(24221..24235)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     assembly_gap    24294..24303
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <24304..24940
                     /locus_tag="IQ64_RS44840"
                     /old_locus_tag="IQ64_47900"
                     /pseudo=""
     CDS             <24304..24940
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014043973.1"
                     /locus_tag="IQ64_RS44840"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="IQ64_47900"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="RALVGLVYLRRHDTLAQIAAGFGISVGTAHAYTASVIDLLADRAR
                     PAPCPA"
     misc_feature    24712..24714
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 tcaacggcgg ctgctgcttc gactacggca acagcgagac gacccgggcg gccgacgcgg
       61 ccggggcgat ggacgcgatc aacttcagca cccagtgctg gttcggcggg tgcgccggca
      121 gaggtccctg ggtccaggcc gacctcgaat gggggctcta ctccggcggg agtcagagct
      181 ggaacacgaa ccagcgggcc ttcaccggca agttcgtgac ggcgatgctg aagaacaacg
      241 ggacgagccg tttcgcgctc aggggtgccg acgcccagac cgggagcctg accacgctgt
      301 gggacggcgc gctgccgccc ggctacagcc ccatgaagaa gcagggcgcc atcatcctcg
      361 gcagtggtgg tgactgctgc aagcccggcg gcggcgcgaa cctcagcgcc ggcaccttct
      421 acgagggcgc gatggtgtcc ggctacccgt ccgacgcgac cgacaacgcg gtacaggcga
      481 acatcgtcgc cgccggatac cgctgagttg ctcatccatg aagggagaaa cgtgatgcga
      541 caaggcaaca atcatcaccg atggcgcgca ccgatcgccg tggccatcgc cctgttactc
      601 gccgcggccg gcatcagcgg catcggactg acgtccgccg ccgcggccga ggccccctcc
      661 gccgccccga gcgccggatg cggcaagccg cccacgctgt cgagtggtcc gcgctcgatc
      721 cagagcagcg gcaggacgcg gaactacatc ctgcgggtgc ccgccaccta cgacaacaac
      781 cgcccgtacc gagtggtctt cggcttccac tggaacggcg gcaccgccaa tgacgtcgac
      841 tcgggcggaa ccagcggata cccctggtcg tactacggcc tgcgggcgat ctcgaacgac
      901 agcgcgatct tcgtcgcgcc ccagggcctc gggaacggct gggccaactc caacggcgag
      961 gacctgacct tcgtcgacga catgatcagg cagatcgacg cgggcctgtg tgtcgacacg
     1021 aaccagcgct tcgccggggg tttcagctac ggcggcggca tgagcttcgc cctcgcgtgc
     1081 gcccggccga ccgtgttccg cgcggtcgcc gtgtacgcgg gcggccagtt gagcggatgc
     1141 aacggcggta cccagccggt cgcgtacatc ggactgcacg gtttgcggga cccggtgctc
     1201 ccgatcgcca cgggacgttc gctgcgtgac aggttcgtcc ggaacaacgg ctgcactgcc
     1261 cagaacccgc cggagccggc ccggggcagc ctcacgcatg tcgtcacgac ctactcgggg
     1321 tgccgcgccg gctaccccgt ggcatgggcc gcgttcgacg cgggccatac tccgggtccc
     1381 gtcgacggat cgcccggcga ctacgaaccg ggtgagcggt cgtggacccg ggcggtggtg
     1441 tggaacttct tcacgcagct cgacggcgcg gatcccaccc cgccgaaccc ggccacgttc
     1501 cggctgcgca acgagggttc gggccggtgc ctggacgtca acggcgcgag cgggaccaac
     1561 ggcacaccga tgatcatctg ggactgccac ggcaacgcca accagcagtt cacgcagaac
     1621 ggtcaggcgc tgcaggtgct gggcaagtgc ctgaacgttc ccaccgacgc cgccgccggc
     1681 acgcgggtcc agatccagga ctgcaacggt ggcgccaacc agcagtgggc cctcaacagc
     1741 aacggcacga tccgcaacgc gcagagcggg ttgtgcctgg acgtcaacgg agcgagcacc
     1801 gccaacggct ccgcggtcgt cgtgtggagc tgccacgacg gcgccaacca gcgctgggcg
     1861 cgcgcctagc agcacgagag ggccacctcc ccccggggag gtggcccttt cggcgtgccg
     1921 cgtcagctca gggcagggtc catttctggt tggcgccgcc gtggcaggac cacaggttca
     1981 cgagggtgcc gtccgaggag ttggcgcccg acacgtccag gcacttgccc gaccgcgggt
     2041 tccgcagcga tccgtccgtg gaagcctgcc agttctggtt ggcgccgccg ttgcaggacc
     2101 acaggacgac tctcgccccg tccgccgtac tgccaccgct gacgtccaga cacttgccca
     2161 acgccttgac cgtcgagccc ggcgccaccg tccactgctg cctcgccgca cccgtacacg
     2221 acgagatctg caccgccgcc ccgtccgccg aactaccgtc acggatatcc aggcacttgc
     2281 ccgcgccccc cacgatcgga cccgcgcccg gggtgggtgg cgggctgccg cccaggtcct
     2341 tgatccggac gttgcggaac gacacgtcgt cccccgtgcc gtggttctgg atgccgacgt
     2401 ggccggcgag cgagcgggcg gggttcgtgt cggtgaagtc gttgatcttc acgccgttga
     2461 gccagacctg gagccgctcg ccctccacca gcacctcgaa ggtgttccac tcgcccggtg
     2521 ggtcgagcgc cgcatcccgg gcagccgtgt ccggggcctt gacggcgtag atggagccgg
     2581 tcgtgcggtc gggtgcgtcg gtggcgtcga tctggacctc gtagccgttg tccagtgccg
     2641 actgcgggtc gttcgtcggt gggaagccca cgaccacgcc ggagttgtcg tcgccggaca
     2701 tcttccagtc gagcttgagg gagtagttgg tgaactgctt ggcgctgtac cagagcatgc
     2761 ccatgccgcc gtgcgaggcg agggtggcgt ccgtgttggt gaagccgccc gggccggcct
     2821 gcgaccagcc ggtggtggag ccgttgtaga gggtcgtata gccggtttcg gggcggcagt
     2881 cggccttggt cctgcctgcc gcgtaccgga agccgccgag caggtgcgcc cggaacgccg
     2941 gctccgcgta cgccgcctga ctgtgcccgc cgccggtgta gaaggcccgg ccgcccgagt
     3001 gggtcttgca ccagctgtgc gggtggtcgg cacccatcga gccgcccgag tacgacgact
     3061 cgtccagcgt ggtgagcacg cgcgcggtgg tgcgggggtt ggtccggaag ttgtaccact
     3121 cgtcggtgcg ggtccaggtc tgcggcaggt gggcggtcgc ggcgtgcgcc cgtccctcca
     3181 ccttgacgtc ggcccgctgg acagcggggt gcgaggcgaa gtaggcgccg accaggtcgc
     3241 cgtagaacgg ccagttgtac tcggtgtccg cggccgagtg gacgccgacg aagccgccgc
     3301 ccgagccgat gtacgactgg aacgccgact gctgggtgtc gttcaggaca tcgccggtgg
     3361 tgttgaggaa gaccaccgcc tcgtagcggc tcaggttgcc ggtggtgaac tggccgccgt
     3421 cctccgtggc cgtcaccgtg aagttgttcg ccgtgccgag ctcgcggatg gcctggatcc
     3481 ccgccgggat cgagtcgtgc cggaaaccgg ccgtcctgga gaacacgagg acgtcgtagg
     3541 ccgtgtccgc ggcatggacg gggtggggct ggccgagaag gaccagggtg gcgagtgccg
     3601 tggcggcccc gccgagcagg gtccggggtc gtctgcgcat gtgcgtcact cccttcttgg
     3661 tgaccgacat cagggcaggg tccatttctg gttggtgccg ccgtggcagg tccacaggtt
     3721 cacgagggtg ccgtccgagg agttggcgcc cgacacgtcc aggcacttgc ccgaccgcgg
     3781 gttccgcagc gatccgtnnn nnnnnnncat ccaggcactt gcccgcgccc cccacgatcg
     3841 gccccgcgga cggacctccc ccggtgtcga aggtgaacgc gtcgacgtcg aagaggtatc
     3901 cggagccgcc ggcgaaggtc aggtagagcg tggtggtgcc ggccggtgcc ccggagatcg
     3961 agccgttgac cgtggtgaag ttcgtccacg agccggtgac cgggacggtg gcggagccga
     4021 ggacggtgcc ggtcggcgag ccggcccgga cctgcagcgt gccacccgcg ccggctgacg
     4081 acacccgggc actgaacgac gtggcgttgc tcagcctgta cggctcgaac gcgatccagt
     4141 cgccgttctc gatgtcaccg acggacttgc cgccctcggc tgtcgacttg tccaggatgc
     4201 tgatgccgga cgacgtcttg tggtgctcgg cctgccggtg cttcggctgc aggatgtgct
     4261 gggtgtgcgt ggtgagcccg gcgttgtcgg tgtattcggc gtcgaagacc ccgaagatgt
     4321 tcgccgcgtc gtcgtgctca ccgtcgaccg ggatggtgat cgtgcccgag caaccggtct
     4381 tcgaggtgac cgggtggccg tggctgtcgt gaccgacgat gtacgtcatc ttcaccttgg
     4441 cgcagtcgac ggtgccgtcc tccggatccg tcacggtgat ggcgaacggc acggtgtcgc
     4501 cgaaggcgaa gatctccccc gcggcgggtc tgtcgacggt cacggtcggc gcggtgttgc
     4561 cgacggtgat ccgcacgtcg gcggtgccgg tggcgccctg cggatcacgc acggtcagcg
     4621 tggcggtgta gttcccgttc gtgtcgtacg tcttcgtcgg gttggcggcg gtggaaccgg
     4681 tgccgtcacc gaagctccac gcataggtca gtgccccacc gtcgggatcg gacgagccgg
     4741 ccgaggagaa ggtcacggtc agcggcgccg cgccggacgt ccggttcgcg ccggccaccg
     4801 ccgtgggcgc cctgttgcct ccgccgacgt ggtcgaagcg gtacagggcg gagtactggt
     4861 cgccctggta cagcccggca ccgtagtcca gcacgtagta ggagccgtcc gggccgaacg
     4921 ccgagtcgat cacctgcttg ccggtccagg ggaagctgtc gatggtgccc ggggagccgt
     4981 ccgcgttgag gtggatcggc ttgatccagc cgcggccgaa ctccgtggcg aagaactgcc
     5041 cgtcgaacga ctgggggaac ttcgtgggcg agttgaggtc ggggtcgtac cggtacaccg
     5101 ggcccgccat cggcgactcc gagccgccgc cgaacgccgg agggctgccg gcgtcgccgc
     5161 cgtagcggat ccaggcggcc ttggcgggcg gcagcgtgct caggccggtg ttgcggaacg
     5221 agttgttcgt cgccccgccc gagcagttgt acttcgcgcc cgccgtgttg gtggcgaagt
     5281 cccactcggc aaacgtctcg gcgttcgtgt tcgtgccgtt gcagtacggc cagccgtaga
     5341 agcccgggcc cgtgacgcgg ttgaactcga cctggccctg gggcccgcgc gccgaggtgg
     5401 ccccggcgtc gggaccgtag tcgccgacgt agacgatgcc ggtggccttg tccacgctca
     5461 tccggaacgg gttgcgcagg cccatcgcgt agatctccgg ccgggtcctg gccgtgccgg
     5521 gcgcgaacat gttgccttcc gggatcgagt acgacccgtc gtccttcacc ttgatccgta
     5581 ggatcttgcc gcgcaggtcg ttggtgttgg cggcggtgcg ctgcgcgtcg aacgccgggt
     5641 tgcggttggt ccgttcgtcg aggggggcat acccggcgga ctcgaacggg ttggtgtcgt
     5701 cgccggtgga caggtacagg ttgcctgccg cgtcgaagtc gatgtctccg ccggcgtggc
     5761 agcagatgcc gcggtcggcc ggcacgtcga ggacgtccac tttgctggac tggttgatcg
     5821 tgaagtcgcc gttgagcgtg aaccgggaga gcctgttgac accctgccac gtcgaccagt
     5881 tgccgccggt ggtcggtgcg tcgcctcccg gagtggacag cggcggggcg tagtagaggt
     5941 agatgtgccg gttggtggcg aaacgcgggt cgataccgat gccctgcagg ccgtcctcgt
     6001 cgtgcgcgta gacggggatg gtgccgatga ccgtggtggt gccgttggca tcggtgcggc
     6061 gcacggtccc gttgcgagcg gtatgcagca ccgaccggtc ggcgagcacc gccagcgaca
     6121 tcggctcacc gacttccggc acccctcggg ccagttggac ctgctggaag tcggcggcgt
     6181 tgatcgggtg cgccgaggcc ggcgtcgcgc cggacaggtt cgcgacgaga gcggccgcga
     6241 ccaggagcag agtcgaaccg atggccggcc aacgtgcgac tgcagccctg tttattttca
     6301 tgaacatgac agtgccgtcc ccttcctgaa cagatgactg ccaggcttgg ggcgcgcgct
     6361 gccgcgccga tgccgtagcg gaaatcgcct cttcggcccg caggtgtgct tcagcgggcc
     6421 actacgccga gcgagggcaa ccgctcggaa acagcaggag tcgatggcta ccgcgctgtc
     6481 gggtcacatc gacgactgtg atggtccgtc agcaaggcta ggagacttca gcccgacgtg
     6541 tccacacttc cctccggacc ggccagactt agggctagtt gtggagaatg tcacgaaggg
     6601 cccgagccct gtcgggactc ggtgccatct ccgagccgga ctggcgggac gcagacggtg
     6661 gcgcgatctc cgtcgcccgc cccgacgacc gggccgagcc ccggccacac cttcgccgac
     6721 cacgaacaca cccggcgcac cgccgtcgag cggggcgacc acgtcgcacc ctgcgccctc
     6781 ggcgcactcg gcgcgagcca ccacctgtgc ccggccggct gctgcccggc ccgcgccccc
     6841 cgacccgccg ccgcggttcc ggggctcgcg agcgcggtac caccagcaga ccaagaacct
     6901 tctggtgtcg tattcgccga agaagctggg cttcttctag aggcacgaaa aaaggcgcct
     6961 gacctgggct tttgcccgcc aggcgccttc ctctcggccc gccaagagca gggaccgact
     7021 tacgtcataa ctcccagttc ctcccaccgc tgtcccgctc ctgaccagta cttccggacc
     7081 agtcacggac caaaccccga ctcacccctc agactccggg ccctggctga cgcggtccca
     7141 ctcctgcatg gactgctcga tgaggcggtt ggcctgctct cggacgccgt ccaggaactt
     7201 ggcgtagtga cggaagagga cctcgatgct ctggcccgcg cgacgagcgc actcggcggg
     7261 gtccacaccg gagtacagcc agaacgagat cccggcgtgc cggagatcgt agggccgctt
     7321 ggccagcttg gaggcgagtt ctgtacgggt cagaacgtac ttccgtgccc gcgcccacgt
     7381 tgtgccgtat gcagctgcgt ccacgtagtt gccagcctgg ttccggaaca gtcggccgtc
     7441 cggcgccacg ccgaagcgtt cgatgtgtga acggagcatg cgtacgaact gcggcgggac
     7501 aggcacaggc ctggttgcgg tagccgcgcg gcgcttgagg gagtgcacct cgtgcaccga
     7561 gccactgtcc gtccactcct tgcctgaggt gacgacgcca cccgaaaggt tgagcatccc
     7621 ccatccggag tcgggcagat ggcactgttc gagccggaga tgaatgacct ctgcaggccg
     7681 cattgccgcg tagtacatgc agccgaagaa cgcctccagg tgagggccgc gaccacgctg
     7741 ccgggcaacc gccgtgagta gccgggcgac ctgggcggga ttgggaacgg cagccgggtc
     7801 cacctcctcg ttgaccacag gagccttcca cctgagcccg ttgagggggt tctccgtgaa
     7861 gtaacctttc tccacagcaa cattgaggac ttcgttgaac gcagcccgct tgcgccgtgc
     7921 cgtcttggca gcagcctcct taccgtccag cttgaggcac aaggcgtcca gtgcccgccg
     7981 cagcacatcg gcttccgcga gagcgctgac gggcagggag ttccgcttca tccagtccag
     8041 cgcctgccgc cattcctcgg ctggctcttt ctcccatgcc ttcttgttga atgcccagga
     8101 gtacaaggct cgccgcagga cccgcggctc tggataggtc acgccagggc gcacaagggc
     8161 aggcgtgatg gtggcgaatg cgtcggccag tgtgcggcgg gtgtttcccg gcgtgcggtc
     8221 ccaacgctgg tcgaggtatt cgtgcgcaag gtcgtaccat gtcgtccgct gcttgatagc
     8281 tcgcagttcg gacgctggca gccctgtgtg ctgatcgaag ggctcacctt cacgcgctgc
     8341 cgtcatcagc tttgcgcgtc tgctctcggc gagcccgacg gtcatgaatg actctgactt
     8401 ttcgcgccca ttgaccgtcc acctgaccat aaacggcttg cgccgatcga ggcgctcccg
     8461 tatgtcccag aagcggacat tgtaactcat cgccaagtgt cagaatctct ttcgcacttg
     8521 tcccaccagg catccaggtc aggacgacga cacctgagtt caccattggg caacttgatc
     8581 attcggggtg cttccccgcg agcgcgcatt cgatagaacg ccgacggact catacggatc
     8641 tccgcgagaa cctcggcgag cttcagcacc ggagggcgag ccatgcaata tcaccttcgt
     8701 gtcgagaaag gcttcatgcc ggaaatccag gcgcgcatca atacgcagaa gagctcccca
     8761 tttctgcacg gctgccgccc cggagtgaac gacgagacgc agccaggcat cacgcatcga
     8821 tgcagcggat gatttcctca ctgcgcacaa gcgagcggtc cggaaggaga ccttgcgtag
     8881 cgagcagcag tggccgtggg catgaaagtg tgtggtcatt gatgtaccag cagctggcaa
     8941 cagccaccca acatctcctc tcgaatgcgt acggctctgc caactgggtc cgccacggct
     9001 ccaccgccaa gcacagccga atgcgaacac catcaatgct ctggaagatc cccggtttcg
     9061 gtaaccgggg atctgctgct atacatcgcc ctgcactacg acggcctgct cgtcgcgcct
     9121 gtttccgcct aggtcacgag gccaggcggt acgagcggag ggccgggggg cacaatccgt
     9181 gacgagcacg ggcagcctgt agccggtgag ccggtcgagg tttcgcgccc ctacaccctc
     9241 aagtgccaac aacccaggca ccgtggcgcg ttgctgcgct gcggtgcgca tcgaggtacg
     9301 taaagacctc tcggccacgg cgatagccgc gttacagcag atcctcgcca atcaattctg
     9361 gcgcgcagat ctcctgggga gtccaggcgt tcgcggcgcg agcgggacag ggcgcgtgat
     9421 gggggcgagt cggaaggcgg gactcgacag gtggacctcc tcggagcggg acgcggtagt
     9481 ggggcccggc agcgcgggac gcgtactgac atagcggcca accctctgta ggcgggcctt
     9541 caatgccgcg ccccgcggct gacctggtgt tttccgggtc gctgtacgtt gacatgatcc
     9601 cggacggggt tccagtcccg tgggccactt tctcgtctgc cgtgggcgaa tccggcagcg
     9661 cgactgaggc aacctcgcag ggcattggca gtagtttgtg agaaggacgc cggctccccc
     9721 cgctgcgcgg cagtcatggt cggatcggca tcttccggaa aagagctgcg ggatgggtgc
     9781 ctttacggca catcactggg cctgagcggg ctcaaggagc tcaaaatctc gaccgttagc
     9841 gatcaggctg caggaagacg gagcgtgccc cgaatccctg cccaattctt ctactgcgtg
     9901 gtgtaggagg tggcgctcta gtcgtccccg gagaagccgt cgaggttagt gtggaagagc
     9961 tggacggcga agcacgacag tggctcgggc cacctgccca tcagcagccc aaaaccgctt
    10021 cccgggcggc acgcgaccag atggcctgtt gccgggcggt gaaacccatg cggttccagt
    10081 gaaagaggac gtgccgggac acgacgcttc ggaggccgag cccaagccgc ccgtctcgcg
    10141 caatgtccgc cagggcacgc cctccgtgct ccatgccggt cacccaactc tgtaacgacg
    10201 cgagcgggcc gtcattgatt gcagggccgg cgtcgagcag gagtagctgc cgcatcgtgt
    10261 ccgccatggc gctgaccctg tcggcgggaa cgtcttcggg caacggccgt ttggcctcga
    10321 tctgccccca cacgtcgccc tgctcacccc attccagccc ggcggctcgc aggaacaggg
    10381 tggtgacgag cagagaggtg gccttcgcgt cgaggactcc gtcggtttcg ccggcggcgt
    10441 gctggtggta gtcgagtacg cccatgctgt cggtgtggaa cacacggtga gtgatcatca
    10501 tgccgtctgg gccgccgaag gcgacgcttt ccggctcgta caggtacgga caccagttct
    10561 tcaccacgct ccaggacacc gcgctgtcga gggcttcggt tacgtgcgcg atgacctcct
    10621 cggccggtgt gcccgggctg gggtgaacgc gcaggcgcca gcaggggtac ttacgcagga
    10681 accaccacgc tccgacgggt gcaccgcgca gggagggcag gaggtaggcg cggaaggttt
    10741 gttcggcggt ggggtagtcg gcgaactcga tgttcacctg gtgccagccc tcggggctgg
    10801 cgtcgagcgc agtccggcca gcagcgcggt accgctcgac cgcgtcagcg agccgagcgg
    10861 ggctcgtccc cgctcggctc gctgcgtccg cgnnnnnnnn nnnnnnntcg gcattccgcc
    10921 gagaacggac cagatggcgt cctctgccgg gctgatgtcg tgctcgtgca ctgtgccgtc
    10981 ccttcagctc aagagcaggc aggcatccca gtcggtgact gggccggctt cttgttcagc
    11041 gctctggaac gccaggactg ccccggcctc cccttcgagg aatccggccc cctcaggcag
    11101 gtcggcggcg agaaagcgct gcctgagcag gggaaggcgg acggtgaacg cgtgcggggt
    11161 ctctgcgtcc tccgcgaacc gctgcaccgt gcgcaggacg ccgccaacgc cgtggcacag
    11221 gccgcgattg gagagcttgt cgagctggtg cgcgtcgtcc aggcagtaca gcagggcgcg
    11281 ctcggccatc cgtttgcggt cctcgtcgcc gagggctacg gcggcaagct gctgtgcgcg
    11341 ggcaaggccc ggcgtgccgt agcaccagga cggggtggcg gggaggacgg gcgaagggcc
    11401 gacttcgctg atccaccgag gccagcgggt tccgcgatgg tcgctctgtc ggatcccgtc
    11461 gagccagcgg cagatcccgg ccatggcggt gtcgtggccg tccacggtga tgccgcgccg
    11521 tttcgccagg gcgagcagag cgaggggacc gctgatgccg tgcgcgagcc ccgcgttggc
    11581 gtggccgccc tgtgtgatgg tcttgctggc aggcgagtgg gcgacccacc agccgggcag
    11641 ctgttccccg ttggccccgg cgatcggttg ggtgagccgg accaggtact ccaacacgcc
    11701 gcgcagttcg gggccctccg gctgtcggcg caggaggagg gaaccgaggc cggccagccc
    11761 acggaacagg tcgtactcag cgaaggcggt gtagccaccc tggtcgatgc gcgcgtgggc
    11821 ggcgtccagg cgacgccggg tgtgcgcggc cacgatgcgg tcaagggtgt gcagggctcc
    11881 ggcataccgg tcgctgtctg cggccgcgag gtgaaggacg tacgtcatgg cgggggctcc
    11941 gaggaacagg ccggccgtgt ctccgtcgat cagcgggcgg atgccggcga gttgctggtg
    12001 gacgtcgcgc catggggtga ggccgcggtg agcgcgttcg atgtggagca gggcggagcc
    12061 gaggggaccg cgagcaagag actgccgtgt ggcgatggtg gtgtcggtga tgggcggggc
    12121 ggtggtcacc gcttggctcc ttcggtgcgg atggtccagg acagggcggc agcgcgggcg
    12181 aggcgtcggc aggttgcttc ggcgtcgggg gcgatcccgg tagcgcggtt gtggtgcata
    12241 tgcagcaggg acccaaggac tgacgccgga tcgatgccgg ttgcttcgag caccgttcgg
    12301 taggcgagca gggcggcttg gcgtgtggcc cacgcctgcg caacggcgtc tccggcttgg
    12361 atttcttgga tcgggcagtg gtgctcagcg ctggtgaggc gtacgacgag ggcttgtacg
    12421 tctcggggca gggcggtggc gccgtcgctc tgggggaagt tcgccgttag ccatgcccgg
    12481 ccggcctccg gtgttccgag gaaggcggtg gcgatgtcga cgaagctggc ggcggtgact
    12541 gcctgccggt ggctgtcagg gagaggcaag gcgatctgtg tcagggcggc atcggagtcg
    12601 gctgcgaaga acctttcagc ggcctccagg gcggccccgg tgccgtagcg cccggtttcc
    12661 ggctcgtcgg tgtcccaccg cacccgctga agcagcccct cggcccgcag ctcagccgcc
    12721 caggtggcaa cgcgctgggc agtgttcccg aacgcgtccg gggacggaag ccgcaaccgc
    12781 aggcgcacgt ggctgtcggg gtccgcgtag cggatgaacc accactccag cggttcgact
    12841 tcccccagca ggagtggcac gtgcgcggtg agcagttcgg gtacccgtgc cgcgttgccg
    12901 tacagcttca ggtacgtcca cggggaggcg cccggcagtc ggccggagtc ccggcccacg
    12961 acggccgctg tccggcggac cgcggccggg gcgggccgct gatcggagat gaagggcacg
    13021 gtgacctcat gggcgcggcc cagccagccg aacgcgtcct ccggcggtgc ctcgcgcagc
    13081 atcacggttg ggtggcggtc cagttcggct cgcaggagtt ggtggtgggc cgggaggtcg
    13141 aggtccaggc gcagccgctg gtcgtcgttg ccgacgtaca ccgtgcgggg cactctgcgg
    13201 cgggcgcgcc agtcagacaa ggcggatgcc cagttgccgc cgtcgacgag gtcggccgtg
    13261 cggagccgcc aggaggcagg ggacaggatg gtacggccga cgcgtacctc gggcaggaac
    13321 ggaagccggg ccgccgcgcc ccacgcgaac gggatcaggg tggccgtgtg cgagcggtgc
    13381 agctcggaga cgaagcgaac cagaggatgg gtggcgttgg tcaactccac ggcgttcatg
    13441 accatcggct cgatcacctg gcctgtggac agcgacacca ggtagaggcg ccgtgcgtca
    13501 gcgacaacac cgaggtggtc cacgtcgagc gtggcgtccg ggttgtactc gcccacggag
    13561 agcacgttcg gcatgagggc gggggcgcgg ccgacgttgc gggtacgcac gcgcagcgga
    13621 ggactggaca cctgtcccag gtcggcaccg gcggtgagcg tcggcagtgt ggagtacgcg
    13681 gcggccatgc ggtcgaagtc ggctgcctcc agcatcgtca ggaagcgtcc cgtggtgata
    13741 ccgacgctca gggacagtcc tttgatgacc agtgcgaacc cgccgtcttc cacatcgttc
    13801 agggagcgcg cgagcaccgt gaaggacagt gcgacgtgcg cgggcacctg ggtgggccgg
    13861 ccgagggcca gggcctcgat gtctgcttcc gtgaggtcga ccgtgcgctg atcgttcagg
    13921 gcggcgtcct gggcgagggt gaggaggtgc tcgtctcgaa gggtcgtggc cagcaccggc
    13981 cgtttgagga ccgtgccgcg gtagccggcg ggaaaaccga ggccggtgtc cgggtcggtg
    14041 aggtcgcgca ggggcacgat ggtgcccatg ctgtagcgct ccagaaagcg cgtgcggtag
    14101 tcctgccagg ccgctgagcc gttcgggaac ggcgtcagcc gggtgatgac ctgtagggca
    14161 tgctccgcct cgcgggtcac ggtgtcgggt agaacgatgt cgcagtccgg gcggagattg
    14221 accaccaggc tgcggtcggt gatgccggtg agggcgttca tcttcgccgt ggccttggcg
    14281 cggagcgtgc gctgggctcg ctgtggggcc tcgtcgtggc gggtgaggag cgtgcgggcc
    14341 tgacgcagtt catcggcttt ggcgggcgcg acgctggtgg tgtcgagttg ctcgactaag
    14401 tgcccgagtg cgtcaccgca cgtcatgggt gcgtggaggc tggtcaggag cacgcggtgc
    14461 tcgacgaggc tgtgcagcat ggcgtggatc tgctcgtccg gggtgtcggg gtagtcgctg
    14521 cggagcttgg cggcgagagt gctgacggtg atcggtgtgc gggccagggc taggacggtc
    14581 tccacggcgg gggtgcgacg cagcgtggtt tcggtggggc cttcggcgcc cggctggaag
    14641 aggagggcaa ttcgcgaacc gcggacgatg catctggaat tggcgacgac gggtacgttc
    14701 cgcagcacgt ccgggtcacg ttccagtgtg gtgatgacgt cgttcagcca ctcagcgtcg
    14761 gcgtggacga aggcacggtg ctcggtgccc cagtccacgt gactggcagc gccgatgcgg
    14821 atgggggccg gcccggcgaa cagcccgaac ggggtggccc ggtactgcat gcgcagcacg
    14881 tagcgggcca gggagatggc ggtgcgccgt acggcccgcg agcgctggca ctggccggcc
    14941 gccacttccc ggatggagtc ggcgaggcgg ggggcagcga attcgatcgc ggcggccctg
    15001 atgtcgtcgg cccacacctg ggtgatccat tcccgccaca gatcagtgtc tgctgactcc
    15061 tcgccgacca gtgttggcca tggaggcagc ggcgctgcca tgggaaacac cgacgccctg
    15121 atcatgcccg cgtcaacagt gtgatacatg gctgtacccc cttgggtctc gcggtggggg
    15181 ccaggccggt aaggaacggc ccggcccccg acttctgttg ttactcgcag gtgctgttgg
    15241 agcaggcgga ctgacaggtc tggccgcagc cgtcgccggt gtcgttcagc agcgcgccga
    15301 tgaccggcgc ggacgcgacg gtctcgatgc tgaggtcgaa gtccgaccct ccgtgcattg
    15361 cgaagtccgt gccggacttc agggtcgtgc cggtgctcct cggtgccatc tcgttctcct
    15421 ctacagaggt gggtggatgt gctcttaccg gcctggtcgc gacgccggcg gcgttacgac
    15481 caggagatcg tgacccgggt gtgccggcgg tcgatgaccc ggccgacggg gagttgctcg
    15541 tccggcgtcc cggcggggtg aacctcgatg tgcgcacgct gtcggcggtg ttcgccgttc
    15601 cagacctgga actcctcgac cagacgctcg gcgacctcct tgccctgcgg cccatggccg
    15661 gcggcgccca gctcgaaacg gtcggggtcc tcggtggcgc gcaccgtccg gtaggcgaag
    15721 ctgtcgccgt ccaccagggt cggcacaccg agcggcgtcc tggcggcgac gaggccgcgt
    15781 tgccgggcgg cgggtgtcgc tgccatgagg ggcaggttgt gcaacgcgct cgccagccac
    15841 aggtccagct gctccttgga ctcgtcacca gcgagcgtca cccccgacca ctcctcggca
    15901 cgaggcgagc gcagcgcggc ccgcagagcc tcggcatcag gctcggggtg atcgtccagg
    15961 cgaagggcga tctcctctcc ctcgacgtcg tggaggacag ccagacgcat gcggttctca
    16021 ccgacaccct gcatcggcac gaacccgcac agctccaccc cgtcgctgac caggtgctgg
    16081 ccgtcgcgga cgaacgcgac ggtgcgggtc atgccgcgca tccgcagcgg gacgaccagc
    16141 cggccgccct cggcaagctg gtgaatccag gcgggtggga tgtcggcggc ctgcacggtg
    16201 atgatgatgc ggtcgtacgg ctggtgatcc ggcgcgccat attcaccgtc ggcggtgatc
    16261 actgtgacgt tgctgtagcc ggtcgccttc aaaaagtcct tggcgcgccg ggtgatatcg
    16321 gggtcgatgt cgagggtgac gacgtggccc ccgtcaccga ccaactctgc gaggtaggcg
    16381 gcgttgacgc cgccggagcc gatctccagg accttcatcc ccggccgaat gtcagcctgc
    16441 tcgatctgca tggcttggat gcgcggcgcg gacacggagc tgacctgcgt gccagtggcg
    16501 tcggtcttgg tgatcgtggc ggtctcgggc tcgtaaacct tggccatgtc ctcgtcaggc
    16561 gtggcgaggt ggcggggaac cgaacggaag gctgccacga cgcggggact gcgcgcggca
    16621 ccgagttcga tcagctgctt caccatcctg tcgcgcaact cctgctcaga ggcagggctc
    16681 ttgtcgctgt tctcagtcat gccggggacg tttgtcacga gcagtctcct tctcggcgcc
    16741 cgcgcgccga ggtggtcggg agcggataat tggggtcggg ctaggagggt ctggacacgt
    16801 cggttgcctc cgggaggcgg tgatctgtcg cgcggcgctt cccttcgtaa gatgccggcg
    16861 agctgccgcc catgaagtag gtgagtgcct gcgccttgag tcggttaagg cagtcctcgc
    16921 acgtcatgaa cggtgcatgc tggccgtccc actgcaccgg gccgagccag gtaaccggca
    16981 ggtcggtacg cgtgcacccg agccagcagt cgcctgtgac ccatcgggag ctcaggcatg
    17041 tggtcatgtc acatctcccc tccctggaga ccgcaaccga gcggcaccgg aggcggccgc
    17101 gaatacgagg acacccgtga tcgagtcgag cagtcggcac gcgggagtgc tctgagacgc
    17161 gtccaggaac gagggcaaag ggctgtggct cgtcatgttc cttctcgtca acatctaggt
    17221 aggccccagc caccccggaa cgagcggccg aggggccaag ctcactcttc agccggagag
    17281 cgccggaagg aggtgcaatg ccgcgcccgc tccgggctcg ccggtcatcc gaaggcaggg
    17341 cggcagctca gatcgcgcgt agctgggccc gacgttcctc ggcgacaaca acgcaactgt
    17401 ccgtgtggcg atagccatgt atgccgccgc tcgcctccga tgcgaacagc acgcgttcgt
    17461 aggactcccc agaggcgatc agctgggagc atgcgccgca gattcgcccc cgtatggcct
    17521 cctcgatatc gctcgtgccc gtcgacggcc cgagcgggcc ggggttctcg aacagcgtca
    17581 gcagtgcacg agagatgacc gcgaggtcct gcgcatggca tgccttcgcc acctgcgact
    17641 tgccggcacc ctcctccagg aggcgatgag cgcgcactat gacgtagacc gctgcgtggc
    17701 gcatctcccc tcgcatacgg gcggcgatgg cagtgacctc cgggacgagg agctgtacat
    17761 gcccgcgcag ccgaccgaga agggtcttca gtttcacgag ttccggtggg caggtgcccc
    17821 atacgtcgag gccgacggtg tacgtctcgc ggatcgtgtg cgcgtcgacc ggcgcgcgct
    17881 cgttcaaagc ggtcacgacg ccccccgcgc tcgtccactg tcgctcgcct cgtcgccacg
    17941 aaccaggaag ttggcccaca cgtctttgcc gcccgtgaac tcggagcaac cgcagtcgtc
    18001 ggcgaagctc gccacgagga gcaagccccg gccgcactca gcgtccgcgg cgtcgtagga
    18061 gagcttgggc aatgcgggat cgaagtcgcg cacgcagacg ttgagtatgc ccgtcagacg
    18121 cgtgaccgtg agtcgcgcgc ccctcgtccc ggtgccggga agaggatctg tgtgccgcag
    18181 gacgttggtc agcagctccg taaccgtcag ggctgcactg tcgatcaggc cggatagacc
    18241 ccaaagctcc aagtgggccc gaactacggt cctgatgatg ggcacggcct ctgaggtcac
    18301 gtcgaggtct atctccaggt gccccgactt gctgcgcgtc gtcgcgcgta cgccggttgc
    18361 tggcacggcg ggcagttcca agaggtcggc catcaaagat ccaattcggt ctggcgaatc
    18421 ctcaccaatg aggtttgact gcggtgtgta ctggtgtgga accggtcagc aaccattcag
    18481 tcaggtcgcg agacccacgt gcatatccgg atgcggagac ctgagatatc cgcatcacga
    18541 cccaggggac gctgatgccg cagcccgaga aggagctcaa ccccgacgcc tcgccacagg
    18601 catggttcgg cgctgaactg cgccactggc gtaagcgtca accaggtctg cgggctgccc
    18661 agttggggcc gatggtgcag gtcagcccgg atgtgatctc caagatcgaa aagggctcgt
    18721 accggtgccg acgtgacctg gcagagcgtc tggacgatgt ccttgagacg ggcggagtcc
    18781 tcacccgcgc gtgggggatg gtgttcggcg atgcggataa aaggcggcgt gatgcggata
    18841 gtgcccgccg aggaccggtg gaggggacga ttcaggtcca tcaagggcgc atgctgggca
    18901 cagacccgtc agccccgcta tccgagagcc ttacctcagt ggaccgacgc gctttcctgg
    18961 ctgccaccag ccttgccgcc ttcgccccga tagaactcgc ccgactcgtc gcgccaaccg
    19021 caccgccgga gcttccgaag cggattcgcc ccacggagct ggatcagctg cgcctcatcg
    19081 ccgacagcat ccaccgctgg gacaacgcgc agggtggtgg gggtctggtc ggtgacttcg
    19141 cgagtcgctc gatggagtgg gccgtacggc tactcttcgt cgcctgcccg gagcagctcc
    19201 gcccggatct tctcagcagc atcgcgcggc tgggcatcgt ggtcggcgcc actcacttcg
    19261 acgcctatgc tcacggcgag gcgagggtcg ctttcaaggt cgcttccgaa tgcgcggagg
    19321 aggccggcga ctggtggctt cgcgccaaga cgttttcctt cctctcccga caagcgactt
    19381 ggctcggcga tcctgacgaa ggtctcacgt acgcggagaa ggggcttgtc cgcgccgacc
    19441 ggctcacccc gaccattcag gccatgatgc acagcgcacg cgcacgagcc ttcggcaaga
    19501 tgaacgacgt ccagggcacg atggccgcag taggtgcggc cgacgatgcc tttgcacgct
    19561 cgaatccggc caaggacccg gcgtggatgc actactacga cgaggcccag caccacggcg
    19621 acacagccca tgcgctgttc gacctgtcca ttcatgccga gcaggacccg gggcgggcgg
    19681 cgcagcggtt cacaacagcg gtcgtcggcc acggcgacga ctacgcccgc tcgcgcggta
    19741 tctcccgaac gaaactggcg tcgctcctca tggccaaggg cgaccctatg caagcgatta
    19801 ccatcgggca ccaggcgctc aacgacgtcg gcaggctcac ctctcggaga gctgcggacg
    19861 acctcaggga actccgccga ttcgccgggc aacaccgcac gctggaagag gcggcgcagc
    19921 tgcgccaacg gatcacagct accttgcagg catgacgaac tcggttgccc ccgcccgcgc
    19981 cgtactggaa gaagcctgcg cccgcgcaag cttcgacccg gcaggcgccg agcccgttcg
    20041 cctcgccgag aacgagatat ggcgcctccc ggatcaggtg atcgtccgca tcgcccgcgc
    20101 cggccagtgg gatgcggccg tgcgagaggt ccgcgtggcc cgctggcttg ccgacaacga
    20161 gctaccggct gtccgcgcgc taccggtcga acaaccggtg gaggccgcgg gccgcccggc
    20221 gacgttctgg gctgagctcc cacggcatga gatcggcacg gttcgggatg tggtcgtgct
    20281 gctgaaacag ctccacccgt tgcctctgcc tggcttcccc ctcgaccggc tcgacccgtt
    20341 cgtacgggtt gccgagcgga tcgaggcagc gacatccctg tcggaagatg atcgagcgtg
    20401 gctgcgacat cgacacgcag aactccgcga gtggtgggag cacagaccca tgggcctgcc
    20461 cgagtgtctt gtgcatgggg acgcctgggt cggcaatgtc gcgcgcaccg ctgccggccc
    20521 gatcctgatg gacttcgagc gggcctctat cgggccgccg gagtgggatc tcgtctcgac
    20581 agcagtcaag ctcacgacga ccggcacggt caccgagtcc gagtacgccg agttctgcca
    20641 ggcgtacgga agggacgtca cggagtggga ggggtacgaa ctccttgccg gggcacgtga
    20701 gttgcgtatg accacttacg cagcccagca tgcagccacg cgacccgagt ggcaggccga
    20761 agcgcagtac cgcgtggact gtctgcgggg tcgtgcagaa gcacgtccgt ggcgctggaa
    20821 agggatcatg taacgcccat cggaaccctt caagtagtgg acgtgctcct cagctccgcc
    20881 gacagccagc caacatgctt cgcgacctct tctgtgccgg agaacctttg aaggtcccgg
    20941 tcatagcaga tcaaaggact ctagatgcat ggccagggcg agaagggtac ggtcggcgta
    21001 cggtgcgccg atcaactgga ctgcaatggg caggccctgg tcgtttgtgc cgacggggac
    21061 gatgacggcg ggcaggccga tgtggctgat gaggttggcc cagccggtct gatcgaagaa
    21121 gctgcgttcg tgcccgttga tctgaagggt tcggctgccg ttcgggatgg cgggggtcgg
    21181 ggcagcaggg gtgaggagca cttcgtggtg ctcgaagaac gccgtccacg cagcgcgttg
    21241 acgggcgcgc tcttcacggg cgataagcca gctgcggtgg ggctgggtgc gatggcgcag
    21301 ggcagtggct cgaagagagg tgtcgtcctc gcatagttgg cgtgcgctgg tcaggtctgc
    21361 tgtgaacgcg tcgtcgctgc cagctaggga ggcgttggcg tggaggagct gttcgaagag
    21421 ttgcgatgcg tcagtgaagc caaccgggcc gcgggttgcg gtgatgtgcg ctccggtggc
    21481 gcccagctgg cgggtgagca gttcgagcgt cgcggccgtg gcgtcatcga cggggcagcc
    21541 agggtcgctt ggccagatgg cgatgcggaa gtcatcgagc tgtcggggcg gttcgggcag
    21601 gctcagtcgc catggtgtgt gttcatccgg ggtgggcgtg gtgagtgccg tgagcatgag
    21661 ggccaggtcg cgggggtgtc gggcgagagg gccgggggtg agcatgtcgc tggtggtcag
    21721 ccagccgggt ggtcggggaa tgtgtcctcg ggcagagacg agtccttggg tggggcgcag
    21781 ggcgtagacg ccgcagtagt gggccggcag gcggagggag ccggcgaggt cgctgccgag
    21841 ttcgaggggg gtcagtgcgg cggcgatggc tgctgcggcg ccgccggagg agccgccggg
    21901 ggttcgggtg gggtcgtggg ggttgtgggt ggttccgaag agggtgttgt cggtgtggag
    21961 gtcctggcag taggcgggga cgttggtttt gcccatgatc acggcgccgg cgtggcggag
    22021 tctcgcaacg gcatcggcgt cctgctcggg gatgtggtgg cggaggtctt cgcttccgca
    22081 ggtggtgcgc aagtgggcgg tttcgaagga gtccttgatc gtgagcggca gcccgtcgag
    22141 caggccgacg ggttcgcctc gggtccggcg tgtgtctgag gcgtcggctg ctcgttgggc
    22201 ggcttcgatg tcgagggtga tgacggcgtt gagggtgctg gcctggatcc gttcgaggtg
    22261 gaggtcgagc aggtctcggt tggagatcgc gccttgttgg agtgcgttga gctgggcgtg
    22321 ggccgggagg tccgggtagc tggtgttcat gtgctgacgg cctcgggggc tgtgggttgg
    22381 tcgtgccggg cgaagtgtcg agcgatggca cgcagggccg ggaggtcctc gatggggtgc
    22441 caggactcga tgttctggtc ggcgaagtcg gtgggctggg caggcagcgt gccctctgtg
    22501 tgagcggtga gtgcggcgcg gatctggtcg gcggtgaccg ccgcgtggag ttcgtctccc
    22561 gtgaggccgg cggcccggtg ccgttcttcg ctggcctgcc gtatgtggtg gtcgaggtag
    22621 ggacgcactg cggtctgtcc gtcgcggatc tccacgaccc ggcggtacac ctggaagggg
    22681 atgccgcggg tgtgcgatcg gtcgtcggcc gtggagtcgt tgggggtgag ggcgatctcg
    22741 gggacggcgc ggtagaagac gagccacagt ggatgcagct ggcggtgagc acgtcggagg
    22801 tcccactggt aggtggcgtg ccgtgtttgg gcggtgagcg tggggatgag ccagccgacc
    22861 agggtgagga tcgttccgag gtcaccgcag atccaggcga agtcctccca gccggtcagg
    22921 gaggtgccca gggctgcggc ggtcacgttc ccgatgcgca cggcactgta gccgagggtc
    22981 acggccgcgc cgacggcgac ggtgcgcaga ccaacgcgta cggccgtgcg cgggctgcgg
    23041 ctggccagac gccagctcgc cacgctcaag tagacctcgg cgagtgtgta ggcgctgatg
    23101 tagaccgtca ggtaggccgc gtagatgtgg tcgtgcgcgt agtacagggt gaagtccgtg
    23161 ggccgctgga cggcgggggt cagcaggaag aacagcacga acagtgcggt gatgacggcg
    23221 gcgccggagc cgagccagta ccgggacatc tggcgggccc ggtcggcggc tgaactccag
    23281 tggctcagga cgtggggcag agatcgatca gcaggcaacg gtggacgggg catactgccg
    23341 cgatcccaag acgccaccac agcggccata ccggtctctc tgcaaggcag cacgggcagg
    23401 cccgacttga cgtggtcaac atccattcac gaagagcgac aagccgcatc gacgtccggt
    23461 cgctcggctc caggcccgcg aagtcgagtg cggtcccgtc ataccgggcg agctgcatgg
    23521 cctgaagcgt tcggaccggc aaccctgtcg catcgcgcag gccgctgagg ctctcagggg
    23581 tgagaatgac tccgaaaaac acgggccgag tgattgccgc gccttcggaa cactccaacc
    23641 ccagtgcgtg ggcagcccgg ccgggaggag cgctcagcgt gcccgcaaca cgatctaccc
    23701 aggaggagaa agcctcgccg ctaaccggct tcgggacgac aggaagccgg cgggcacggg
    23761 gtacggcaac aggactacgc gcaggcactt gtgggatcgt gtgtctcgca agcacgtgca
    23821 ctgccgccaa tgccgccccc tcccacttgc gcgtccgtct caggctcttt cggcggcctc
    23881 tcctgacgaa cgcgtgaaca ccggccccag taggccactt gacgttattc attccccgat
    23941 gtccacgacg agaacccgtc tgaggtagtg gcctcgcacg cggtggccgt cgcctttgag
    24001 gtagaccatt cggtatggcg gacgaggcgg tcaaccaatg cagtccgaga ccccgcctgt
    24061 cagtgagcgt tttcagctcg gccactgatc gggtgacgct ggtggtgtgc gcaacgcacg
    24121 aggctcccgt gccgttgggg gaggtgttcg aagtctcaac ccaaaggcac aggagccgcg
    24181 ttggttccgt attctgccgc gctcgacctg cctcacgccc tggccgagtg ggtcaccgtc
    24241 accatgctca tcgtcacccg cgagggtgac cgccgctgca aactcccgcc gcannnnnnn
    24301 nnncgtgccc tggtcggtct ggtgtacctg cgtcggcacg acactctggc gcagatcgcg
    24361 gccgggttcg gcatatccgt cggcaccgcc cacgcctaca cggcctctgt catcgatctg
    24421 ctcgccgacc gggcccggcc tgctccgtgc cctgcgtgaa gccgacccgg agtacgtcct
    24481 gctggacggc accctcgcgg agtgcgaccg ggtcggcgac agccgagccg actattccca
    24541 caaacaccgc cgacacgggg tgaacgtgca gatggtcact gatccagact gccagctgct
    24601 gtggatctca cccgcactcc ccggccgcgc ccacgacctg acggcggcgc gcaaccaccg
    24661 gatcatccgg atctgcgaac gccaaggcgt cccagtcctc gctgaccggg cttacatggg
    24721 agctggctca tgggtgacga cacccctcag gcgcccgccg ggccgcgagc tcacaccgac
    24781 ccagcaaacc gtcaaccgcg cgctgtccgc agcccgggcc ccggtcgagc gcggcgtcgc
    24841 acggctgaag tcctggcgca tcttccgccg gtcccgctgc agcccgaatc gaatgacgtc
    24901 aattgccgct gccgtcctca cgccggagcg gcaacgctga aagagctcaa tcaccccgat
    24961 cacgaccgac cggccaattg cccgttactg acccacgctc ctagccctcg gcctcggcgg
    25021 ggttctcctc gcccagctcg gcccagaccg tcttgccttg cctggcatgg cgcgttcccc
    25081 agcgctcggc aagctgggcg acgagaaaca ggccgcgtcc tccctcgtcg aagacccggg
    25141 cccggcgca
//
