LOCUS       NZ_KQ257870            22226 bp    DNA     linear   CON 02-JAN-2025
DEFINITION  Streptomyces stelliscabiei strain P3825 scf_652_97.1, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ257870
VERSION     NZ_KQ257870.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces stelliscabiei
  ORGANISM  Streptomyces stelliscabiei
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 341513)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Genome sequencing of plant-pathogenic Streptomyces species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 341513)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JUL-2014) Biosciences, University of Exeter, Geoffrey
            Pope Building, Stocker Road, Exeter, Devon EX4 4QD, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001189035.1-RS_2025_01_02
            Annotation Date                   :: 01/02/2025 01:49:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,536
            CDSs (total)                      :: 9,455
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 81
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 482
            CDSs (without protein)            :: 482
            Pseudo Genes (ambiguous residues) :: 0 of 482
            Pseudo Genes (frameshifted)       :: 129 of 482
            Pseudo Genes (incomplete)         :: 407 of 482
            Pseudo Genes (internal stop)      :: 20 of 482
            Pseudo Genes (multiple problems)  :: 69 of 482
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:19:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 144667
            Orig. end                         :: 166893
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ257870.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22226
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22226
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22226
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12226](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12226)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(489..509)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.59"
                     /tool="antismash"
     gene            1309..2637
                     /locus_tag="IQ64_RS31440"
                     /old_locus_tag="IQ64_33135"
     CDS             1309..2637
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973118.1"
                     /locus_tag="IQ64_RS31440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33135"
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="WP_046916037.1"
                     /transl_table=11
                     /translation="MQAEPKKSLVGEEYEVEVGPVAHGGHCIARTSEGQVLFVRHALPG
                     ERVVARVTDGEEGARFLRADAVSVLTASKDRVEAPCPYAGPGRCGGCDWQHAKPGAQRR
                     FKGEVIAEQLQRLAGLTPEEAGWDGTVMPAEGDKVPAGEVPAWRTRVQYAVDAEGRAGL
                     RRHRSHEVEPIDRCMIAAPGVSELGIEKRDWAGMASIDAIAATGSQDRQVILEPRPGAR
                     LPIVELDRPVSVMRVEEKDGGVHRVHGRPFVRERADDRTYRVGSGGFWQVHPKAADTLV
                     KAVMQGLLPRKGDMALDLYCGVGLFAGALADRVGDKGAVLGIESGKRAVEDARHNLAGF
                     DRVRIEQGKVDAVLPRTGIDKVDLIVLDPPRAGAGKKTVQHMASLGARRIAYVACDPAA
                     LARDLGYFKEGGYRVRMLRAFDLFPMTHHVECVAILEPASKAL"
     gene            complement(3216..4445)
                     /locus_tag="IQ64_RS31445"
                     /old_locus_tag="IQ64_33140"
     CDS             complement(3216..4445)
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124854.1"
                     /locus_tag="IQ64_RS31445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33140"
                     /product="flavin-containing monooxygenase"
                     /protein_id="WP_046916036.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-13, bitscore:
                     44.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSTPQRNLSAPTIVIGAGPHGLAAAALLNRSGEPAVILERSDRV
                     GASWAQRYDHLRLHTTPGTSSLPGLSLPRQAGPWVSRDDYVRYLESYVAHHRLDVRVTT
                     PVQRIERAEPGPGAQWLVHTPDGPVTADAVVVATGRCHTPNLPDWPGRSTFTGTLLHSA
                     HYRSPAPYRGQDVLVVGAGNSGTEIASVLAGAGAARVWIAVRTPPNILPRSSARWHAAG
                     RLTEILPLAWRDRTSLLTQRLAVPDLTSRGLPRPRTGLYTRNAREGVNPVLDHGFVDAV
                     RSGQVEPVAAVQAFDGPDVVLADGTRRRPDTVIAATGYRPNLHDLVGSLGVLNEDEQPL
                     AVGAQTHPEASHLYFTGYTNPLTGVLRQAGIEARAIAHALRRETVRVPLPSPRVGDRTT
                     DTLHRGHASS"
     gene            4846..5394
                     /locus_tag="IQ64_RS31450"
                     /old_locus_tag="IQ64_33145"
     CDS             4846..5394
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981441.1"
                     /locus_tag="IQ64_RS31450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33145"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_404819292.1"
                     /transl_table=11
                     /translation="MDLDVPAGTLVGVVGENGAGKSTLLQIAVGHLAPDCGTVARTGAV
                     GYCPQQALLNDAFTVGQHLRLFQVAYRLPTLERADELMELLALTGCRRQQVGELSGGTR
                     QKLNLLIALMHDPQLLVLDEPYQGFDWDTHQRFWALAADLRDQGRSIIVVSHLLHDLHH
                     FDAIAHLRQGRLHFEETER"
     gene            5391..6182
                     /locus_tag="IQ64_RS31455"
                     /old_locus_tag="IQ64_33150"
     CDS             5391..6182
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124852.1"
                     /locus_tag="IQ64_RS31455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33150"
                     /product="hypothetical protein"
                     /protein_id="WP_046916035.1"
                     /transl_table=11
                     /translation="MSLSWTAFTELLRCTLQGHLRNRLALALAVAFIPIWIFVARLCTS
                     DQVVRIWLDAISGHVSAPAGQVGQVASALGAITMVAGFVAFTETFQSREVDRRLLLAGY
                     PRLPILLAKLAAVALTAALLALYTTILLWISLPVRHAAPLALALAGAGLAYGGIGLLLG
                     SLVRGELEGFFLIIMLSLVDTGLQNPVFNTLMDVAGVSALPLYGVNQLALSSALTSQIP
                     WFHGLLSLIWSAATGALALLVLHTHRPSRSPWSRRTRAQAG"
     gene            6763..7107
                     /locus_tag="IQ64_RS31460"
                     /old_locus_tag="IQ64_33155"
     CDS             6763..7107
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ64_RS31460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IQ64_33155"
                     /product="hypothetical protein"
                     /protein_id="WP_046916034.1"
                     /transl_table=11
                     /translation="MTATTAAATVQGGSQWVQTGPLAFNHPLTTTAERISEVPELTIPF
                     PGVWELTYHVRTSFSSGNQRALWIHTWLDKDGVRIEGSEARTAARARIPKRFRTRSDRR
                     SWSLSRSGRR"
     gene            complement(7482..7799)
                     /locus_tag="IQ64_RS31465"
                     /old_locus_tag="IQ64_33165"
     CDS             complement(7482..7799)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014132.5"
                     /locus_tag="IQ64_RS31465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33165"
                     /product="SCP2 sterol-binding domain-containing protein"
                     /protein_id="WP_046916033.1"
                     /transl_table=11
                     /translation="MVHEDIGSGLERHADEARKVDYQFHVVITGQGGGDWRVNPQAPKV
                     VQGDPGGADLTITMNSSTFAEFYDHPRQTLMTGSFAGKINMAGNQMAGEKFADLIELAK
                     K"
     misc_feature    7864..7877
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.74"
                     /tool="antismash"
     misc_feature    7950..7963
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.8"
                     /tool="antismash"
     gene            complement(8059..8382)
                     /locus_tag="IQ64_RS31470"
     CDS             complement(8059..8382)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ64_RS31470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="HNH endonuclease"
                     /protein_id="WP_050399290.1"
                     /transl_table=11
                     /translation="MEGQGRCGLHPVPLAEAWDSGGWRWTKAERVAYANNLDVEHHLIA
                     VTPRSNRQKADKDVTQWLPIEPARCRYVTEWVAVKRDNQLSVDESERQTLIDLPSQCPA
                     EVA"
     CDS             complement(8590..>9569)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=2
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="IQ64_RS31475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_159392208.1"
                     /transl_table=11
                     /translation="VVVTLAGTGWWVPESRHPRPGPGPPDRVGMGAVTCGMGALVWSII
                     QGPVRGWIDPAIGAGFILAVLAFALLPWWEKRHPAPLLPPRLFADRRFTAAVAALAWMF
                     FALFGSLFLLTLYLQTQLHYAPAQTGLRLLPLAAALGAGAGASLLIAPRWGDRLTVTTG
                     MLLVASGFGFLALAPPVSGYGPAVGYQLVAGFGAGLAAPPATEAVLGAVPGEQAGTGAA
                     VNDLVREVGGALGIAVLGSLLAAHHAQAGAPRGPLPHSPPAGPCAALPAAPSVTFMNGL
                     HTASWAAAAAALSAALIAAVGLPRHAGPAHPAAQPAHAPQLESEL"
     gene            complement(8590..>9571)
                     /locus_tag="IQ64_RS31475"
     assembly_gap    9572..9595
                     /estimated_length=24
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<9596..10070)
                     /locus_tag="IQ64_RS53710"
                     /pseudo=""
     CDS             complement(<9596..10070)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="IQ64_RS53710"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /product="MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPGSPRTAHPGRALAVLCTGLFLIGLDVTVMNVALPSLQSALDPG
                     PQGLLWIADAYTLALACCLLVAGVWSDTHGRRRAFTLGLALCGAASVAGGLATGTGQVV
                     AARWRWAAVRRC"
     gene            complement(10001..11128)
                     /locus_tag="IQ64_RS31485"
                     /old_locus_tag="IQ64_33190"
     CDS             complement(10001..11128)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="IQ64_RS31485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33190"
                     /product="terpene synthase family protein"
                     /protein_id="WP_050399291.1"
                     /sec_met_domain="T1TS (E-value: 3.5e-59, bitscore: 195.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPAELPEGFWTFYCPLEEEIGADAERLSANCAAWAQKFDLGRGD
                     PNLSALYGAGGATLITHAFPHASTNPDLAQVLADYSAWAFMADDFIVPDPDARADVLHA
                     VYRWARTMLCARSWESHTTHLDDALRNVFERLRACMSDVQYERFTTTQADWLHAELWER
                     ALSERGTPLTVNDYLAVRLGAVGVHATPGCLDAVEGTELTAQEWSSPLVKAATEAGLFA
                     AALDNDRYSFCKERDLTQVNYNLFGALQHEHPDWTLEQAMLEGIRIRDTMLALYLRLRE
                     QILPTASPDLRKYLTGVELVISGDITFGTTCMRYFAPEAAPDIRRTVMPPANLSDEPLP
                     YPTVAWWWEHIAPCQGPRVPRTRVGPWQCCALVCS"
     gene            complement(11204..12226)
                     /locus_tag="IQ64_RS31490"
                     /old_locus_tag="IQ64_33195"
     CDS             complement(11204..12226)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="IQ64_RS31490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33195"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_159026221.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-61, bitscore:
                     202.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADSPRDCETILAQTATLVRPLVRSRVHTLPPQIRHVAGLHFGWW
                     TDDSTVLKAPPVSKGVRPALALLACRAVGADPCAARAAAVAVELVHNASLLHDDVIDED
                     PLRRGRPALWAAKGVPAAILAGDALFFAAVQSVAEAPDAGRTVPVLLAAVQALIEGEYL
                     DTLMGSGTDVRADRAAEVAAGKTGALLACACELGATAGGAGPERAQLLHGFGRRLGIAY
                     QCVDDVLGIWGEEPVTGKPALSDLRSRKVTIPVAAAMAGHTPQARSLRALYSANGPLSE
                     EEAARARDLIEQTGAREATLRRARRHPADALHLLDQVRPEPVAAAELAALADLITHRDH
                     "
     gene            12704..13294
                     /locus_tag="IQ64_RS31495"
                     /old_locus_tag="IQ64_33200"
     CDS             12704..13294
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543124.1"
                     /locus_tag="IQ64_RS31495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33200"
                     /product="isochorismatase family protein"
                     /protein_id="WP_046917625.1"
                     /transl_table=11
                     /translation="MRRALIVVDVQKDFCEGGSIPVKGGAGRAVAIADLVRRADGKYAH
                     IVATRDHHIDPGAHFSEHPDFQNSFPEHCVVGGEGGEFHPGFAPAVTSGGVDEVFFKGA
                     YSASKSGFEGSAEDGTSLADWLRARHVSDLDVVGIATDHCVKATALDGVRAGFAVRVLL
                     NYTAGVAADTTSTAINELRQAGVKLSGKPVVLA"
     gene            complement(14159..14596)
                     /locus_tag="IQ64_RS49775"
                     /old_locus_tag="IQ64_33205"
     CDS             complement(14159..14596)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ64_RS49775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IQ64_33205"
                     /product="hypothetical protein"
                     /protein_id="WP_192781752.1"
                     /transl_table=11
                     /translation="MIRIVLPVIFMEILLLRYGGPVTTRSLDRKSARTGAGEEGLSMDR
                     QSLPREENAGRRARSCRNWTGAAGRAVAKAHRVGETLAYEGVVQELIARSRSDFAQPSL
                     LVLETAWLIDRHGAKVATAGAATFTAAISARATDPRLASNS"
     gene            14565..15314
                     /locus_tag="IQ64_RS31505"
                     /old_locus_tag="IQ64_33210"
     CDS             14565..15314
                     /NRPS_PKS="Domain: PKS_KR (6-166). E-value: 1.9e-09. Score:
                     29.6. Matches aSDomain:
                     nrpspksdomains_IQ64_RS31505_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020661046.1"
                     /locus_tag="IQ64_RS31505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33210"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_046917627.1"
                     /sec_met_domain="adh_short (E-value: 3.2e-31, bitscore:
                     102.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMTGNTILITGGTSGIGLGLAVRLHEAGNKVIVAGRRKELLDEI
                     TAEHPGIDAVVLDVADPDSIARAREAVAASHPGLNVLVNNAGIQLLESVLDPAGLQVAE
                     DHVATNLLGTIRMTYAFLPLLVGKDDAVVMNVTSALAFVPFPITPTYSATKAALHSFSE
                     SLRIQLASADAGVQVIEVVPAGVRTTLMGQQDSEQSMPLDDFLTEVLDLLREKPDAKEL
                     VVEPARFIRDAVATGSYDDVLAMMTGS"
     misc_feature    complement(14566..14580)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.04"
                     /tool="antismash"
     CDS_motif       14583..14675
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IQ64_RS31505_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IQ64_RS31505"
                     /protein_end="37"
                     /protein_start="6"
                     /score="17.4"
                     /tool="antismash"
                     /translation="TILITGGTSGIGLGLAVRLHEAGNKVIVAGR"
     aSDomain        14583..15062
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IQ64_RS31505_PKS_KR.1"
                     /evalue="1.90E-09"
                     /label="IQ64_RS31505_PKS_KR.1"
                     /locus_tag="IQ64_RS31505"
                     /protein_end="166"
                     /protein_start="6"
                     /score="29.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TILITGGTSGIGLGLAVRLHEAGNKVIVAGRRKELLDEITAEHPG
                     IDAVVLDVADPDSIARAREAVAASHPGLNVLVNNAGIQLLESVLDPAGLQVAEDHVATN
                     LLGTIRMTYAFLPLLVGKDDAVVMNVTSALAFVPFPITPTYSATKAALHSFSESLR"
     gene            15819..16655
                     /locus_tag="IQ64_RS31510"
                     /old_locus_tag="IQ64_33215"
     CDS             15819..16655
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129253.1"
                     /locus_tag="IQ64_RS31510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33215"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_046917628.1"
                     /transl_table=11
                     /translation="MDKRELAAFLRHRRETLRPRDVGLVEGPRRRTQGLRREEVAQLAG
                     MSTDYYARLEQQRAPQPSVQITAALARALRLTLDERDHLFVLIGHNAPARFHRSDHVSP
                     TLMRVLDRLDDTPALVTTDLVDTLAMNPLAVALLGDQTRHTGLASSGYYRWFMDPAERL
                     VYPEETHESHGRAQAARLRAALTAGSDTPRAARILAELQEHSPEFVRMWELQEVARYGD
                     CKTLLHPEVGRIDVDVQLLYTENRAQTLVVLTTRPGTESHSKLELLSVIGRQQLTP"
     misc_feature    complement(16826..16839)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.37"
                     /tool="antismash"
     gene            16900..17493
                     /locus_tag="IQ64_RS31515"
                     /old_locus_tag="IQ64_33220"
     CDS             16900..17493
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474373.1"
                     /locus_tag="IQ64_RS31515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33220"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_046917629.1"
                     /transl_table=11
                     /translation="MSAGEQRGRKPRADVQRNRAALLETAQRHFLRHGIGTSLEAVAKE
                     AGVGPATLYRHFPTREALLAAVLQTRSEELVARRTGIEQLGDPAEALDQWLRAMEEYFS
                     AYSGLPEPLMAAARAQEPDSPLTIPCDILITATDQYVRAAQRAGHVRASVRGHDLFLAA
                     CSVAWIKGTGTEEESLDRLRTLIASGYRQRDTQA"
     misc_feature    17593..17608
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.94"
                     /tool="antismash"
     gene            17594..18331
                     /locus_tag="IQ64_RS31520"
                     /old_locus_tag="IQ64_33225"
     CDS             17594..18331
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474372.1"
                     /locus_tag="IQ64_RS31520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33225"
                     /product="NADPH-dependent F420 reductase"
                     /protein_id="WP_046917630.1"
                     /transl_table=11
                     /translation="MKITVIGAGAIGGNLAVKLSTAGHDVQVADARGPEAVRAEVLESG
                     ARAVDLADAVQGRDVIVLSIPFGVAGQLADLFASVPDETVVIDTANYYPGMLSEPIEAV
                     DNGQVESVYTAEQLGRPVVKAWNAALAETQRAKGVPAGAPGRLAIPVAGDNEQARRVAM
                     SLVDDTGFDPYDAGTLADSWRQQPNSPAYCTELTLAELPAALAAADRTKDAAIRDSLPE
                     RIAALGANLTVDDVVEMNRAAHR"
     misc_feature    complement(17595..17609)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.86"
                     /tool="antismash"
     misc_feature    17596..17609
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.79"
                     /tool="antismash"
     misc_feature    complement(17596..17611)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.07"
                     /tool="antismash"
     misc_feature    complement(18521..18535)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.32"
                     /tool="antismash"
     gene            18538..>18639
                     /locus_tag="IQ64_RS46355"
                     /pseudo=""
     CDS             18538..>18639
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512809.1"
                     /locus_tag="IQ64_RS46355"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="NAD(P)-binding domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKIGILGTGNIGKTLTRRLSAAGHEVKAANWPGP"
     misc_feature    complement(18580..18595)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.61"
                     /tool="antismash"
     gene            complement(19338..>19535)
                     /locus_tag="IQ64_RS46360"
                     /pseudo=""
     CDS             complement(19338..>19535)
                     /GO_process="GO:0030638 - polyketide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.5"
                     /locus_tag="IQ64_RS46360"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ester cyclase"
                     /pseudo=""
                     /sec_met_domain="PF07366 (E-value: 1.3e-11, bitscore: 38.5,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DLPGIPATGRPITMTATVIHRIENGKLAEKRSSKDLLGLLQQLGV
                     IPTPGGASGWSRPAAIRADL"
     misc_feature    complement(19629..19642)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.01"
                     /tool="antismash"
     misc_feature    complement(19638..19653)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(19638..19653)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.33"
                     /tool="antismash"
     misc_feature    19993..20005
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.16"
                     /tool="antismash"
     gene            complement(20121..20906)
                     /locus_tag="IQ64_RS31530"
                     /old_locus_tag="IQ64_33235"
     CDS             complement(20121..20906)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978033.1"
                     /locus_tag="IQ64_RS31530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_33235"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_046917632.1"
                     /transl_table=11
                     /translation="MPADAKSPKKLRNNRAALTHKVGYALRHPGRVAPYLSRAGRDAWL
                     RLKHPDHVGYYRAVMASDTRRNPEAAVGSQTHDRWLALGQMQFDYLTEHGLRPEHRMLD
                     IGCGNLRGGWRFIDHLDAGHYYGIDISPDILIAAKRTLAERHLQDKLPHLTITGDLTLD
                     FLPSDHFDVIHAHSVFSHSPLDVIEECLAHVGRVLTDTGFFDFTFDRTEGAEHQVLRED
                     FYYRTETLLALTRKHGLHACFMDDWEERPHGQSKIRVSR"
     gene            complement(21001..21987)
                     /locus_tag="IQ64_RS31535"
     CDS             complement(21001..21987)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978034.1"
                     /locus_tag="IQ64_RS31535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transporter"
                     /protein_id="WP_046917633.1"
                     /transl_table=11
                     /translation="MNGSLRTGSLWHGSLWLAWRQQRVLAGVGAAALATAAAIAAYNRS
                     GMLDALHSGLFDHCGTGPLYCTQSDTGVPLLLDIEPLKYLGTLNIVLPVIIGVFWGAPL
                     LGRDRELGTHRMVLAQGVSRGRWFASRMALAAVTTVAVSGVLAGLFAWWWQPAADRSYG
                     LFWYENTALSGSGPSVVAAALFGLAAGTLLGLLARRVLAAMGLTLLVTGATTLLLQWTH
                     RTRLLVPPHTYTSAGSIPKPPMDEKWSTGHYGLITASGRYDDVMNCPFPSSAQLKECMA
                     QHGYVARFYEANPASDYWTFQWTDTALLGGLALLLTAVTMLLLRRRV"
ORIGIN
        1 ggtggccgcc gccgtcttcg gggacggcac gttcctcttc gtcgtgctgg ccgccgccac
       61 cgccctcgtg ctgttcctgg ccgccaacac cgcctacaac ggcttcccgc tgctcggttc
      121 gatcctcgcc caggaccgct acctcccgcg ccaactgcac acccgcggcg accgcctcgc
      181 cttctccaac ggcatcgtgc tgctggccgg cgccgccgtg ctcctggtgt ggatctacgg
      241 cgccgactcc acgcgtctga tccagctgta catcgtcggg gtgttcgtct ccttcacgct
      301 cagccagacc ggcatggtcc ggcactggaa ccgccatctg cgcaccgaga aggacccggc
      361 caagcggcgc cacatggtcc gctcccgcgc gatcaacacc ttcggcgcct tcttcaccgg
      421 cctggtcctg atcgtcgtcc tcggcaccaa gttcacgcac ggggcctggg tcgccctgct
      481 cggcatggtg atcttctacg cgacgatgac ggccatccgt aagcactacg accgggtcgc
      541 cgcggagatc gccgcgccgg agggcccgag cgacgacgtc gtccgcccgt cgagggtcca
      601 ctccgtggtg ctgatctccc ggatccaccg ccccaccctg cgggccctcg cctacgccaa
      661 gctgatgcgc tcgcacaccc tggaggcgct cagcgtcaac gtcgacccgg tcgagaccaa
      721 ggccctccag gaggagtgga cgcggcgcgg catcgacgta ccgctgaagg tcctcgactc
      781 gccctaccgc gaggtcaccc ggccggtcat cgagtacgtc aaggggctgc gcaaggagtc
      841 gccgcgcgac gcggtgtcgg tgatcatccc cgagtacgtg gtcggtcact ggtacgagca
      901 cctgctgcac aaccagagcg cgctccggct caagggccga ctgttgttca cgcccggtgt
      961 catggtcacc tccgtgccgt accagctgga gtcctccgag gtcgccaagc ggcgggcgcg
     1021 caagcggcag gagtggagcg cgccgggctc ggtacggcgc ggaccggcgc acgagcggcc
     1081 gaaggaatcc tcggccaagg cgtcggccaa ggcgtcgggc aaggcaccgg acaagccgtc
     1141 gggaacgtcg tcggccgacc acggctgacc cgctcccggg ccgacgcgcg cccgggccac
     1201 gcgctccccg gccgacgttc gtggtcaacg gtcggacggc acccacgtag actggtgggc
     1261 tgttgtccgg ccgttgtcgc gttccccatc ttctggagtc accccaccat gcaggcagaa
     1321 ccgaagaaat cgctggtggg agaggagtac gaggtcgagg tcggccccgt cgcccacggc
     1381 ggccactgca tcgcgcgtac gtccgagggc caggtcctct tcgtccggca cgcgctgccg
     1441 ggcgagcggg tcgtggcgcg ggtgaccgac ggcgaggagg gggcgcgttt cctgcgggcg
     1501 gacgcggtct cggtcctcac ggcctccaag gaccgtgtcg aggccccctg cccctacgcc
     1561 ggccccggcc gctgcggcgg ctgcgactgg cagcacgcca agcccggcgc ccagcggcgc
     1621 ttcaagggcg aggtcatcgc ggagcagctg cagcggctcg cgggcctcac gcccgaggag
     1681 gcgggctggg acggcacggt catgccggcc gagggcgaca aggttccggc gggcgaggtt
     1741 ccggcgtggc gcacgcgcgt gcagtacgcg gtggacgccg agggccgggc cgggctgcgc
     1801 aggcaccgct cgcacgaggt cgagccgatc gaccgctgca tgatcgccgc gccgggcgtc
     1861 tccgaactgg gcatcgagaa gcgcgactgg gcgggcatgg cctccatcga cgcgatcgcc
     1921 gccaccggtt cgcaggaccg ccaggtgatc ctcgaacccc ggccgggcgc gcgcctgccg
     1981 atcgtcgagc tggaccggcc ggtgtcggtg atgcgggtcg aggagaagga cgggggcgtg
     2041 caccgcgtgc acggccgccc cttcgtgcgc gagcgcgcgg acgaccgtac gtaccgggtc
     2101 ggcagcggcg gcttctggca ggtccacccc aaggccgccg acaccctcgt caaggccgtc
     2161 atgcagggcc tgctgccgcg caagggcgac atggcgctgg acctctactg cggggtgggc
     2221 ctcttcgcgg gcgccctcgc cgaccgggtc ggcgacaagg gcgccgtgct cggcatcgag
     2281 tccggcaagc gcgcggtcga ggacgcgcgg cacaacctcg ccggcttcga ccgggtgcgg
     2341 atcgaacagg gcaaggtcga tgcggtactg ccgcgcacgg gtatcgacaa ggtcgacctc
     2401 atcgtcctgg acccgccgcg cgccggggcg ggcaagaaga ccgtccagca catggcgtcg
     2461 ctgggcgccc gccgcatcgc ctacgtggcc tgcgacccgg cggcgctggc gcgggatctc
     2521 gggtacttca aggagggcgg gtaccgggtt cggatgctgc gggcgttcga tctgttcccg
     2581 atgacgcacc atgtggagtg cgtggcgatt ctcgagccgg cttcaaaggc gctctgacct
     2641 gcgattttct tggactgctc aggtgcgtcg aggtgtgccc gacctgttcc ccgaaataca
     2701 cgacgtggaa cgtgtcctgg tgccggggaa tgggtttgat ctgcggcttc gtggggcgtc
     2761 tcgcgaggtg atgggcgcgt tcccctccgt ccatgggggc gtatgggaaa ccgtcctgac
     2821 gctcatttga cgctgtttcc gacggagcgt caggtgggtg gctgctcctg cgggtgcgta
     2881 ggaagaagaa tcgtgtatca gagcgtcatc aacgggacga ggcgccgagg ttgcggttgg
     2941 acctccacct acgtctccga ggagcatccg caccctttcc cgcgtcggga cagttgacct
     3001 tctcctcgcc gggacgacct ccacccgctg cagggcatgg gccgatccac cggccgcctc
     3061 cttctcgtca gcggcccgtc gccgtcagct gacgagaagg aggccgacag gtcctggccg
     3121 acggcctagg aacaagggac tgtgtcgccg taggcgcgac gccatccact cgccctgcgg
     3181 ggcacgccgc tgaaggaccg agcttccgag gctcgtcaac tcgaagcgtg ccctctgtgg
     3241 agcgtgtcgg tcgtgcggtc gccgacgcgc ggggagggaa gggggacccg caccgtctcg
     3301 cgtcgtagcg cgtgcgcgat ggcgcgcgct tcgatgccgg cctgacggag gacacccgtg
     3361 aggggattgg tgtatccggt gaagtacagg tgcgaggctt cgggatgggt ctgtgcgcct
     3421 acggcgaggg gttgctcgtc ctcgttgaga acacccaggg acccgaccag gtcgtgcagg
     3481 ttgggccggt acccggtggc ggcgatgacc gtgtcggggc gccgtcgggt gccgtcggcc
     3541 agtaccacgt cggggccgtc gaacgcctgg acggctgcga ccggctcgac ctgcccggac
     3601 cggactgcgt ccacgaagcc gtggtcgagc acggggttga ccccttcgcg ggcattgcgg
     3661 gtgtacaggc ccgtgcgggg ccgggggagt ccccgtgagg tcaggtcggg caccgcgaga
     3721 cgttgcgtga gcagggaagt gcggtcgcgc cacgcgagcg ggaggatctc cgtcagccgg
     3781 ccggccgcgt gccatcgggc gctggagcgg ggcaggatgt tgggtggggt acggactgcg
     3841 atccataccc gtgcggcccc ggccccggcc aggacgctcg cgatctccgt tccgctgtta
     3901 ccggcgccga ccaccaggac gtcctgcccg cggtaggggg ccggagagcg gtagtgggcc
     3961 gagtggagca gggtgccggt gaaggtcgaa cgtccgggcc agtcggggag gttcggggtg
     4021 tggcagcggc cggtggccac cacgaccgca tcagcagtca ccgggccgtc gggggtgtgg
     4081 accagccact gggctcctgg acccggctcg gcccgttcga tgcgctgcac cggggtcgtc
     4141 acccggacgt cgagtcggtg atgggcgacg tagctctcca ggtatcgcac atagtcgtcc
     4201 cggctcaccc acgggcccgc ttggcgcggc agcgacaggc cggggaggct cgaggtgccg
     4261 ggagtggtgt gcaggcgtag atggtcatag cgctgcgccc agctcgctcc cacccggtcc
     4321 gatcgttcca ggatcacggc cggctctccg gagcggttca gtagcgcggc ggccgccagg
     4381 ccgtgggggc cggctccgat cacgatcgtg ggagcgctga ggtttcgctg cggtgtcgag
     4441 ggcatcgcct cctacaacgg cggaccgcgg agcgggtcac gctcgacggg gaggcgcaaa
     4501 gcctgtgaag tggtggtgtc ggctgctcaa cggacagcgg gtggctgccg ttacaccagc
     4561 ggtacggact cgttggacac cgggcagcag cgcggcggat cggtccgccg agggcaagac
     4621 cgtcgggact gtccggccgg gcgcggctga gcggtcatga gccgggcagg ccaggggaca
     4681 tgagcctgcg cggcctcggc ctgtgcggcg ggctccgggt cggctcgctc cacctgtccg
     4741 atctttcgag gggctcatgt gcaggcagta acgacgtgcc accggccacg gctgcggatc
     4801 agcggagtct gcaaggcgta cggcggcagg cagatcctgc gcgatgtgga tctcgacgtg
     4861 cccgccggga cgctggtggg agtcgtcggc gagaacggcg cgggcaagag caccctgctg
     4921 cagatcgccg taggccacct tgcgcccgac tgcggaacgg tggcacggac cggggcggtc
     4981 gggtactgcc cacaacaggc gctgctcaac gatgcgttca ccgtcggaca gcatctgcgg
     5041 ttgttccagg tggcctaccg gctgccgacg ttggagcggg ccgacgagct gatggagctg
     5101 ctggcgctga ccggctgccg gcgccagcag gtcggcgagc tcagtggcgg aacgcgacag
     5161 aagctgaacc tgctgatcgc tctcatgcac gatccgcagt tgctggtcct ggacgagccc
     5221 taccagggtt tcgactggga cactcatcag cggttctggg ccctggccgc cgatctgcgt
     5281 gatcagggcc ggtcgatcat cgtggtttcg cacctgctgc acgacctgca ccacttcgat
     5341 gcgatcgctc atctgcgcca gggccgtctg cacttcgagg agaccgagcg ttgagcctct
     5401 cctggacggc attcaccgaa ctgctgcgct gcactctgca gggccacctg cgcaaccggc
     5461 tggccctggc tctggcggtc gcgttcatcc ccatctggat tttcgtggcg cgcttgtgca
     5521 cctccgacca agtggtgcgt atctggctgg acgccatcag cggccacgtc tccgctccgg
     5581 ccggccaggt gggccaggtg gccagcgcgc tgggcgccat caccatggtc gccggcttcg
     5641 tcgccttcac cgagaccttc caatcgcggg aggtggaccg ccgtctgctg ctggcgggct
     5701 acccccggct gccgatactg ctggccaaac ttgctgccgt cgccctcacc gccgctctgc
     5761 tggccctcta caccacgatc ctgctgtgga tctccctgcc cgtacgccac gcagcacccc
     5821 tggcgctggc ccttgcgggc gccggcctcg cctatggcgg catcggtctt ctgctcggtt
     5881 ctctggtccg tggcgagttg gagggcttct tcctcatcat catgctcagc ctggtcgaca
     5941 ccggcctgca gaatcccgtc ttcaacacgc tcatggatgt ggcgggcgtg tccgcgcttc
     6001 ctctgtacgg cgtgaaccag ctggcgctga gctcagccct gacctcgcag atcccctggt
     6061 ttcacggcct gctctccctc atctggtccg cagcgaccgg cgccctggcg ctgctcgtcc
     6121 tccacaccca ccgaccttcc cgctccccgt ggtcccgcag gacgagagcc caggcagggt
     6181 gatcactgtg cggacggtcc tcctgcggga ttctgcttgg cccgaggact gtcccatcag
     6241 cggtgtgagt gggttgccgg tggcggctca ccccttgtcc gcgaatagtg cgcgcggcat
     6301 ttcgcgtcat tactgctgtg ccgcaggggg tgtgcgcagg gcaaccatgg cgacgtcgtc
     6361 gttgtcgctc gggcggacct ggtccagcag ggagttgcag aagcccgtga acctgccgcc
     6421 gtcgatttga cctggtggta ttggacgcaa ggcgagccag gtctgcgtcc agtacgccgg
     6481 cccgcacgac ctcgctgccg gtcagcacat gaagttcgct tacgggcagg acgacttgcc
     6541 ggcccgtgtc gcccgctacg tctcgttcga ggagtaccga gagccccaga acgtcacccc
     6601 tgactcgccg agtgtgcagc tgcaacatcc gccgcatcta cggcccggag aaggaggctc
     6661 cgggcttgct tctgaaccgg cttgcgcttc ctgaccactc gacgggtggg tttgccagga
     6721 cgatgcttct tactctgtgt gaccaaagct accgttttag tcatgacagc tacgacggct
     6781 gcggccaccg tccagggcgg ctcgcaatgg gtacagaccg gaccgctcgc cttcaaccac
     6841 ccgctcacca ccaccgcgga gcgcatctcc gaggtgccgg aactcacgat ccccttcccg
     6901 ggggtgtggg agctcaccta ccacgtccgc acctcgttca gctccggcaa tcagcgggcg
     6961 ctgtggatcc acacctggct ggacaaggac ggcgtgcgca tcgagggcag tgaagcacgc
     7021 acggccgcca gggcccggat accgaagcgg ttcaggacac ggtcggacag gcggtcctgg
     7081 tcgctctcca ggtcggggag acggtgacgc tccacggccg ctacgccgga gagggcaacg
     7141 cctccgttct cagcaacgac ggcggacgca cctcggtcgt ggcgcactgg gcgagcccag
     7201 ggttctgatc gccaccgcga ctgtgggtgg ggcggggcag cacggctcac ccacagtcgc
     7261 ggtcagcggc tcggcctgca cggggggcaa cgcatggccc gagggatcgg gtacgcggga
     7321 tcagtctgaa cctcgctggc ggcgtgcccc gagacggtcg cggccctccc gtggccggtg
     7381 cgctgaccgg ccctgctcaa tctcgccggg attgcctgtg cgtcaactgc tcacaccggg
     7441 atgagcctgc gcgagccctt gccatcccag gtctgtcgcg tctacttctt ggcgagctcg
     7501 atcaggtcgg cgaatttttc ccctgccatc tgattgccag ccatgttgat ctttccggcg
     7561 aaagacccgg tcatgagggt ctggcgcggg tggtcgtaga actcggcgaa ggtcgaggag
     7621 ttcatcgtga tggtgaggtc ggcgccaccc gggtctcctt gcacgacctt cggggcctgc
     7681 gggttgaccc gccagtcccc gccgccctgg cctgtgatga cgacatggaa ttggtagtcg
     7741 accttgcgtg cttcgtcggc gtggcgttca agaccggagc cgatgtcttc gtgaaccact
     7801 tctgcacgtc gacagccatc cgttctcctc tgggtgcttg ggcatagctg gacgattcac
     7861 cctgtcacgc tgggtgtccg cccgtatgcg gacaggcgga agatcactct tcggggggag
     7921 cgaaggggtg ccgccctgcg gccagctccg gcacatacgt tcgcgtgcgg ccgcaacgag
     7981 gttgacggcg ccgcgtcggc tgggcagctc tggcagggcg gctgggccgc cggccgtccc
     8041 agccggtgcg cgggtaggtc aggccacttc tgcggggcac tggctgggga ggtcgatgag
     8101 agtctgccgt tcgctctcgt cgacgctgag ctggttgtcg cgtttcacgg cgacccattc
     8161 ggtgacgtac cggcagcgtg ccggctcgat gggaagccac tgggtgacgt ccttgtcggc
     8221 tttttgccgg ttggaccgcg gggtgaccgc gatcaggtga tgctcgacgt cgaggttgtt
     8281 ggcgtacgcg acgcgttcgg ccttggtcca ccgccagcca ccggagtccc acgcttcggc
     8341 gagcgggact gggtgtagac cgcagcggcc ctgtccctcc acgcccgcat ccgcccttca
     8401 tgacctttcg ctgtcatgta ggtagcgccg gcgggggatc tcgccgcatg gataccgcac
     8461 cggctcacct gtgtgaacgg cgccgttcac acactcgctc ctgaccagcc tgctggcggg
     8521 accgctgcgt cggcaaacgc tgctgtccgg gctgggagtc cgagggccgt tccagaaggc
     8581 gtgctcagct cacagttcac tctccagctg cggtgcgtga gcaggctgcg cggcagggtg
     8641 cgcaggccct gcatggcggg gcagccctac ggcggcgatg agcgctgcgg acagggcggc
     8701 cgccgcggcg gcccaggaag cggtgtgcag gccgttcatg aacgtcaccg agggcgcagc
     8761 ggggagggcg gcgcaggggc ctgccggtgg ggaatgcggc aatggtcccc gaggggcgcc
     8821 ggcttgtgcg tggtgtgcgg cgaggaggga gccgaggacg gcgatgccga gggctccgcc
     8881 gacctcgcgg accaggtcgt tgacggcggc cccggtgccg gcctgttcgc cgggcaccgc
     8941 tccgaggact gcctcggtgg cgggtggagc cgcgagtcct gcgccgaagc cggcgaccag
     9001 ctggtagccg acagcgggac cgtatccgga aacgggcggg gccagggcca ggaaaccgaa
     9061 tccggacgcg accagcagca tccccgtggt gacggtcagt ctgtcgcccc agcgcggtgc
     9121 gatcagcagc gacgcgcctg cccccgcgcc cagggccgcg gccagcggca gcagccgcag
     9181 cccggtctgg gcgggggcgt agtgcagctg ggtctggagg tagagggtga gcaggaacag
     9241 ggagccgaag agagcgaaga acatccaggc cagcgcggcc acggcggcgg tgaaccgacg
     9301 gtcggcgaag agccttggcg gcaggagcgg tgcgggatgg cgcttctccc accacgggag
     9361 gagggcgaac gccaggacag cgaggatgaa tccggctccg atggcggggt cgatccagcc
     9421 gcggaccggg ccctggatga tcgaccacac cagggccccc atcccgcaag tgaccgcccc
     9481 cattccgacc cggtccgggg ggccggggcc ggggcggggg tggcgggatt cgggaaccca
     9541 ccacccggtc cccgccaggg tcacgacgac cnnnnnnnnn nnnnnnnnnn nnnnnaggcc
     9601 gccgatcacc gggccggcca gcgccccgag gccggccacg aacgcccaca ccgcgacggc
     9661 cttgcggcgg ccggccggat cggggaacac cacggtgatc aacgagagag tggagggcat
     9721 cagcagcgcc gcaccgcagc ccatcgccag cgcgccgcga cgacctgccc ggtgccggtg
     9781 gccagccccc cggccaccga cgccgccccg cacagggcca ggcccagagt gaaggcgcgg
     9841 cgccggccgt gcgtatcgct ccacactccg gcaaccaaga ggcagcaggc cagtgcgagg
     9901 gtgtaggcgt cggcgatcca cagcaggccc tgcgggcccg gatccagagc agactggaga
     9961 ctgggcaggg ccacgttcat gacagtgacg tcgaggccga tcaggaacag accagtgcac
    10021 agcactgcca gggccctacc cgggtgcgcg gtacgcgggg accctggcat ggggcgatgt
    10081 gctcccacca ccaggcgacg gtcgggtaag gcagcggctc gtcactcaag tttgcggggg
    10141 gcatgacggt gcgccggatg tccggggcgg cttcgggggc gaagtagcgc atgcaggtgg
    10201 taccgaaggt gatgtcgccg ctgatcacca gctccacgcc ggtgaggtac ttgcgcaggt
    10261 ccgggctggc agtgggaaga atctgctcgc gcaggcggag atacagggcg agcatggtgt
    10321 cgcggatccg gatgccctcg agcatggcct gttcgagggt ccagtcggga tgttcgtgct
    10381 ggagtgcgcc gaagaggttg tagttgacct gcgtcaggtc ccgctccttg cagaaggagt
    10441 agcggtcgtt gtccaacgcg gcggcgaaga gacctgcttc ggttgctgct ttcaccaggg
    10501 gcgaggacca ttcctgagcg gtgagttcgg tgccttcgac cgcgtcgagg cagccgggtg
    10561 tggcgtggac gccgacggcg ccgaggcgca cggccaggta gtcgttgacc gtcagagggg
    10621 tgccgcgttc gctcagggcc cgctcccaga gctccgcgtg cagccagtcg gcctgtgtgg
    10681 tggtgaaccg ttcgtactgg acatcgctca tgcaggcgcg caggcgctcg aagacgttgc
    10741 gcagcgcgtc gtcgaggtgg gtggtgtggc tctcccagga gcgtgcgcac agcatggtgc
    10801 gcgcccagcg gtacacggcg tgaagaacgt cggccctggc gtccgggtcg ggcacgatga
    10861 agtcgtcggc catgaacgcc caagcgctgt agtcggccag cacctgggcc aggtcagggt
    10921 tcgtgctggc gtgggggaag gcgtgggtga tcagggtggc ccctcccgcc ccgtacagcg
    10981 cggacaggtt cggatcgccg cgccccaggt cgaacttctg cgcccacgcg gcgcagttgg
    11041 cactcaggcg ttccgcatcg gcgccgattt cctcttcgag cgggcagtag aaggtccaga
    11101 acccctcggg gagttctgca gggtgcattt ctgagttctc cctgttcgga tcgaacggcg
    11161 tggcatcggt gggggctgcg ggaacggcgt tgccccagaa gggtcagtgg tcgcggtggg
    11221 tgatcaggtc ggccagggcc gccagttcgg cggctgccac cggctccggc cgcacctggt
    11281 caaggaggtg cagggcatcg gcggggtggc ggcgggcgcg gcgtagcgtg gcctcccgtg
    11341 cgccggtctg ctcgatcagg tccctggccc gcgcagcctc ctcctcactc agcggcccgt
    11401 tcgcgctgta gagagcgcgc agggaccggg cttgtggagt gtggccggcc atggcggctg
    11461 cgacgggaat ggtgaccttg cgcgagcgca ggtcggacag ggcgggcttg cccgtcaccg
    11521 gctcctcccc ccagatgccg agaacgtcgt cgacgcactg gtaggcgatg cccagacgcc
    11581 gtccgaaacc gtgcaggagc tgggcgcgct ctgggccggc gccacccgcg gtcgcgccga
    11641 gctcgcaggc gcaggccagc agcgcgccgg tcttgccggc cgcgacctct gcggcccggt
    11701 ccgcacggac gtctgtaccg gatcccatga gggtgtcgag gtactcgccc tcgatcagcg
    11761 cctgcacggc ggccagcagc accggcaccg tccggcccgc gtccggcgcc tcagccacgc
    11821 tctggacggc agcgaagaac agagcgtcgc ccgcaaggat cgccgccgga actcccttcg
    11881 ccgcccagag cgcgggccgg ccacggcgca gcggatcctc gtcgatgacg tcgtcgtgga
    11941 gcaggctggc gttgtgcacc agttccaccg ccacggccgc cgcccgcgcg gcacacgggt
    12001 ctgcgcccac cgcacggcac gccagcaggg caagggccgg acgcacgccc ttgctgacgg
    12061 gcggcgcctt caggaccgtg ctgtcgtcgg tccaccagcc gaaatgcagc cccgcgacat
    12121 gcctgatctg aggaggcagg gtgtgaacgc gagaccggac caacggccgc accaaggtcg
    12181 cggtttgcgc gaggatcgtc tcgcagtcac gaggtgagtc agccactcga accccttcca
    12241 gggatcaggc catgtccacg ccagaatcaa ggtgcaagcg gggggagggg cagggtgtga
    12301 cgaccagcgc ccgacgcaca cccctggccc actccactcc cgtgcacgac acactgcgcc
    12361 gcacgcgccc ggcccatacc ggccagccag cacacacgta agggcgcggg ttcggctcta
    12421 cgcaccccac agagggggaa ctctgcagtt gcaggcccag tcgaggtcga cttccttggg
    12481 ctgtcaggct gacgacccca tagttctgaa gccggccgat ctaccgatgc gccggacagc
    12541 ggacaaccgc atgggctgtg tcaggtgcgc gtttctcggc caggtgctcg accctttcac
    12601 caagtgcgtc cctatcgggt gagtgctggc gagtaatgcg tcagctcacc gaccgaggga
    12661 gcgaccatac cggcagtgtg ttcttccgaa ggaaagggtc tccgtgcgcc gtgcattgat
    12721 cgttgttgat gtgcagaagg acttctgcga gggcggcagt attccggtga agggcggcgc
    12781 gggcagggct gtggccatcg ccgacctggt gcggcgtgcc gacggaaagt acgcgcacat
    12841 cgtcgccacc cgtgaccacc acatcgaccc gggggcccac ttctccgagc acccggactt
    12901 ccagaactct ttccccgagc actgcgtcgt cggcggcgag ggaggcgagt tccatcccgg
    12961 cttcgctccc gctgtcacct ctggtggcgt ggacgaggtg ttcttcaagg gggcgtactc
    13021 cgcctcgaag agcggtttcg agggctctgc cgaggacggc acgtcgctgg ccgactggct
    13081 gcgtgcccgc cacgtcagtg atctcgacgt cgtcggcatc gctaccgacc actgtgtgaa
    13141 ggccaccgcg ctcgacggtg tacgggcggg cttcgccgtc cgggtcctgc tcaactacac
    13201 cgccggcgtt gccgccgaca ccaccagcac cgcgatcaat gagctacgcc aagccggtgt
    13261 gaagttgagc ggcaagccag tcgtcctcgc ctgagaacaa cggtcgcctt tcgccacagg
    13321 acctgcccgc aacaggcgca ccggccgtgt cacgagtccc ggagcctcca gtggccgtca
    13381 tccgactggc cgtggaggcc cgcccccgga ccgggagacg acggatcagg ggcgcacttc
    13441 ccgaacgtgg cgtggctgct gggggcctac ccgttgatca gcatcacgcc ggggccgccg
    13501 tcgccggcca agccgaacag agccatctgc atggctgggc acagccgccc tcttcggggc
    13561 aagggcgaac tggaggggaa gggcgcggcg cccggccact tccggggccg gtgttgcgcc
    13621 gtcccgtgcc caggccggcc gggccagttg ggagaaccgc cgtgaacgag tcgaggcagc
    13681 ctgacctgtc tctccatagg aagggatggg ttgtcggcca tgacgctcgt ttgacgctcc
    13741 gggcgcccgc aggcggtaca gcgggccaca aaatggcctc tgacctgcaa ctttccggat
    13801 cccgctgaag ccgacatctt gccgatgacg caccacgtgg agtgcgtggc gattctcgag
    13861 ccggcttcaa aggcgctctg acctgcgatt ttcttggact gctcagatgc gtcgaggtgt
    13921 gcccgacctg tttccctcag tccatcgcgt ggagtgcgtc gcaggctcgc gccacatgcc
    13981 tcacctgctg cttcgaagag cggggtgcgg gcgatgaacg ctctgcccca gcttcgtgag
    14041 ggggcggtgg gggaggtgtc ttgacgctcg ttcgacgctg cttctgatgg ggcgtcacga
    14101 ggctcgtgcg cctgaaacag cagcgaggtc aatgatcaaa ctcagactgc acgcgggctc
    14161 aggagttgga cgccaggcgc gggtcggtag cgcgtgctga gatagcagcc gtaaaagtcg
    14221 ccgcgcccgc cgtcgccacc ttggcgccgt gccggtcgat caaccaggcg gtctcgagga
    14281 cgagcaggct cggctgcgcg aagtcgctgc gtgagcgcgc gatgagctcc tggacgacgc
    14341 cctcgtaggc gagcgtttcg ccgacgcgat gcgccttcgc gactgctcgg ccagcggccc
    14401 ccgtccagtt tctgcaggac ctggcccgac ggccggcgtt ctcttcacga ggcagagact
    14461 gccgatccat ggacaaacct tcctctcccg cccctgtgcg ggcgctctta cggtcgaggc
    14521 tgcgggtggt caccggcccg ccgtaccgaa ggagcaagat ctccatgaag atgactggca
    14581 acacgatcct gatcaccggc ggcacctctg gcatcggtct cggcctggcg gtgcgtctgc
    14641 acgaggctgg caacaaggtg attgtcgccg gccggcgcaa ggaactcctt gacgagatca
    14701 cggccgagca cccgggtatc gacgcggtcg tcctcgatgt cgcggaccct gactcgattg
    14761 cccgggcccg tgaggccgtg gcggcgagcc acccggggtt gaacgtcctg gtcaacaacg
    14821 ccggcattca gctgctggag agcgtccttg acccggcagg actccaggtc gccgaggatc
    14881 acgtcgcgac caatctgctc ggcacgatcc ggatgacgta cgccttcctg ccgctgctgg
    14941 tgggcaagga cgacgcggtc gtcatgaatg tcacctccgc gctggcgttc gtaccgttcc
    15001 cgatcacgcc gacctacagc gcgaccaagg ccgcgctgca ctccttctcc gagagcctgc
    15061 gtatccagct cgccagtgct gacgccggtg tccaggtgat agaggtggtc ccggcgggcg
    15121 tgcgcacgac cctgatgggc cagcaggaca gcgagcagtc catgccgttg gacgacttcc
    15181 tcaccgaggt cctcgatctg ctgcgtgaga agcccgacgc gaaggagctg gtcgtcgagc
    15241 ccgcaaggtt catccgcgac gcggtggcca ccggctccta cgacgacgtc ctcgccatga
    15301 tgaccggtag ctgaccgacc tgtagtgacc gacgcggaac cagcagcacg cgggcgggtc
    15361 ctgtggggcc acatgaggga cgaacgcgag cgggacccgc ttcggggtgg tcctcaccga
    15421 ggatgcggaa cggtaaggaa gcgtcttcgg cttcgccccg gtcgtcgcac gagagggggc
    15481 cggctgcgtc ctgagggccg acgggcacgc gagcgcccgg cacggtgaac atcgtcgggc
    15541 cggccgggcc gggcgacgag gcccgggacc ggtcccaagc gggcgtcctt gacgggggac
    15601 cgtcgccgca ggccgtcttc cgtaccggcg gcctgcggcg cactgccggg gcggcgcatt
    15661 gcccagcggg tcatgcacgt ccggtgacca tcgagacttc tcgctgcgag tgcctcgacg
    15721 tcggccgacc gagtgggctt gcgcaggcgg gaagggactg ctcagccatg gatcggcggt
    15781 ctctggatag ccgggcggga tgccacgagg atgagggcat ggacaagaga gaactggcgg
    15841 cattcctgcg ccaccggcgc gagacgctac ggccccgcga cgtcgggctg gtcgaggggc
    15901 cgcgcaggcg tacgcagggg ctgcgccgcg aggaggtcgc gcagctcgcc ggcatgtcca
    15961 ccgactacta cgcccggctg gagcagcagc gtgctccgca gccctccgta cagatcaccg
    16021 cggcgctcgc ccgggcgctg cggctgaccc tggatgaacg cgatcatctc ttcgtcctca
    16081 tcggccacaa cgccccggcc cgtttccacc gctccgacca cgtcagcccg acactgatgc
    16141 gggtcctgga ccgcctggac gataccccgg ccctggtaac caccgacctg gtcgacaccc
    16201 tcgcgatgaa ccccttggcc gttgcgctgc tcggcgacca gacccgtcac accggtctgg
    16261 ccagcagtgg ctactaccgc tggttcatgg acccggccga gcgcctggtg tatcccgagg
    16321 agacccacga aagccacggc cgtgcccagg cggcacgcct acgggccgcg ctgacagccg
    16381 gcagcgacac cccccgagcc gcccgaatcc tcgccgaact ccaggaacac agccccgagt
    16441 tcgtccgcat gtgggaattg caggaggtcg cccgctacgg cgactgcaag accctcctcc
    16501 atcccgaagt cggccgcatc gacgtcgacg tccagctcct gtacaccgag aaccgcgccc
    16561 agactctggt ggtgctgacc acccgccccg gcacggagag ccacagcaaa ctcgaactgc
    16621 tctccgtcat cggacgccag cagctcaccc cctgacgtcc cggaccgggg accgggccgg
    16681 ttcgtgctgc aggggccgga caagggcacc ctggaatggt gcagccggca cggcttctgc
    16741 cctgcgctct gcggccagat atgtcggccc ctgcacttcc gggctcccgt ggtcgggccg
    16801 ccggtttgac cggatgccgc ctccgtttta gtctcgaatg catacggagg cagcatccgt
    16861 tttgatgcgt ccgcaggacc acggcaggca ggagggcgca tgagtgccgg tgaacagcgg
    16921 ggccgcaagc cgcgcgcgga cgtccagcgc aaccgcgcgg ccctcctgga gaccgcgcag
    16981 cggcacttcc tgcggcacgg gatcggcacc tccctcgaag cggtggccaa ggaggcgggc
    17041 gtcgggcccg ccaccctgta ccggcacttt cccacccggg aggcgctgct cgcggccgtg
    17101 ctacagaccc gctccgagga actcgtggcc cgccggacag gcatcgagca actcggcgac
    17161 cccgccgagg cgctggatca atggctgcgg gcgatggagg agtacttcag cgcctacagc
    17221 ggcctgccgg aaccgctcat ggccgcggcc cgcgcacagg agccggacag cccgctcacg
    17281 attccctgcg acatcctcat caccgccacc gaccagtacg tgcgagcagc acagcgcgcg
    17341 ggacacgtgc gtgcctcggt gcgggggcac gacctgttcc tcgcggcctg ctccgtggcc
    17401 tggatcaagg gcaccggtac cgaggaggag tcgctcgacc ggctccgcac cctcatcgcg
    17461 agcggctacc gccagcggga cacccaggcg tagaccgcca ggcgccccgc ccccgcaacg
    17521 ccaggcggca ccaccgcacg gccatcacct cgcgctgccc tcaggggcgg cacaacccct
    17581 caagggacaa ataatgaaaa ttactgtcat aggcgccggt gccatcggcg ggaacctcgc
    17641 tgtcaagctc agcacggctg gtcatgacgt ccaggtggcc gatgcccgcg gccccgaggc
    17701 cgtccgggcg gaggtgctgg agtccggggc tcgcgcggtg gacctcgccg acgccgtcca
    17761 gggccgggat gtcatcgtcc tgtcgatccc gttcggggtg gcgggccagc tggcggacct
    17821 gttcgcgtcg gtgcccgacg agacggtggt catcgacacc gcgaactact accccggcat
    17881 gctcagcgag ccgatcgagg cggtcgacaa cggccaggtg gagagcgtgt acaccgccga
    17941 gcagctgggc cgccccgtgg tcaaggcatg gaacgccgcc ctggcagaga cccagcgggc
    18001 caagggtgtt ccggccggag cacccggccg cctcgccatc cccgtcgccg gtgacaacga
    18061 gcaggcgcgg cgcgtggcca tgagcctggt ggacgacacc ggcttcgacc cctacgacgc
    18121 cgggacactg gccgactcct ggcgccagca gcccaacagc cccgcctact gcaccgagtt
    18181 gaccctcgcc gagctgcccg cggccctggc cgcggccgac cgcaccaagg acgccgccat
    18241 ccgcgacagc ctcccggaac gcatcgccgc cctcggtgcc aacctcaccg tcgacgacgt
    18301 cgtcgagatg aaccgcgccg cccaccgctg agacacccgg cgccgctctc gtccaggcaa
    18361 cgacacgaga gcggcaacgc cggcgcgccg cgaacacaca cgacgaacac gaagaacggc
    18421 gctcacttcg gcaaggccgc cattactcac ccgcaccacc gcgtccgcgg ccggcccgca
    18481 gccccgagaa ccccggtcac agacaccggg gttccgtttc ggacaaggag tttcaccatg
    18541 aagatcggca ttctcggcac cgggaacatc ggcaagacgc tgaccaggcg gttgagcgcg
    18601 gccgggcacg aggtgaaggc ggccaattgg ccgggaccgg ctccgaggcc gcggtcacca
    18661 tcttcatgat cgcctggtag ttggcgggca gcgcgctctc gtccatgccc ggctcgcggt
    18721 gcgggaccag tcgcatcccg cgcgcgcccg gagtcgtcac ccgctccaac tcctcggcca
    18781 cgtccgggtc gtcggcctgc ccgctccgct cggcctcaat gaactgcccg atcaccatct
    18841 cggcggcttc cagccggacc acctcggcat cgatctcggc gagctccttg cgaagccgtt
    18901 cggcgcgatc ggccagcacc actctccgct gcatcaccca gaccagtatg tccgccacca
    18961 gcagccccct tcccacccgg ctctcctcgg agcctgcgag gcactcccaa ccccacatcg
    19021 cgattccggc gaaccggcaa cgcgtcggat gatcacctgc taccgatcac acccccgacc
    19081 ggcacgagca cctcagtctc cgcccacacc atccccacga ccagcgaact cagtttgagc
    19141 aacgctcaat ggcagttgcc ggctagcccg caacccctgc cacagcgcgc ctcgaagacc
    19201 ccccccgctg ctgtcctgcc cccgcgccgg taagaggttg cggagccagc ggtgcatcaa
    19261 gcaacgttcg ccctgttcac atctcgcgta gccggaccga gggcggcgcg ttgcagggcg
    19321 ccaccaaacg tcctgtctca caggtccgct cggatcgcag caggtcggga ccatcccgat
    19381 gccccgccgg gcgtcgggat gacgccgagc tgctgaagga ggccgaggag atccttgctc
    19441 gaccgctttt cggcgagctt gccgttctcg atgcggtgaa tcaccgtcgc ggtcatcgtg
    19501 atcggcctgc cggtggcagg gatgcccggg aggtccctct catggttcgc acctggtcgc
    19561 gggactcaag caggtgttcc gtctgttctg ggaggccaca cccggaaccc acgagatcga
    19621 agaccagatc gcggagggtg acaaagtcgt gacccggctg agggcccgag gactgcacag
    19681 gcgccttcgg gggcgaggac cgtcaccggc gccagccgcc gcagaaggcg cacacgccag
    19741 gtcagtgcct gcgcgcagcc ctcgtccggc acgtccagaa cggccagcgg acgtggccgt
    19801 cgggtcagga gctcgccata ggcctgcagc gccccccagg gccaggggtt gaccatcgct
    19861 ggtagcagct gcgttctgcg tgcctctctc aggaggcgac cgctccgctc ccgggcaagg
    19921 gagatcacca cacacggcac agcgaggtgt ccgccctggc ggcatcggcc cgtccgcacg
    19981 gttcgtcctc gatcgcggta tgcaaggcga gtgtccgcgg gaagcgccgt acgtctccgt
    20041 gttcttgcat cgtctcgcgt gtttcctcgt tcttctcagg gtgtcagggc gagccttctc
    20101 cgcgcgcgcg aggccagagg tcagcggctg acgcgtatct tcgactggcc gtgcgggcgt
    20161 tcctcccagt cgtccatgaa gcaggcatgc aggccgtgct tgcgggtcag ggccaggagg
    20221 gtctcggtgc ggtagtagaa gtcctcgcgc agaacctggt gttcggcgcc ctcggtgcgg
    20281 tcgaaggtga agtcgaagaa cccggtgtcg gtcagcaccc ggccgacgtg ggcgaggcac
    20341 tcctcgatga cgtccagcgg cgagtgggag aagacgctgt gcgcgtggat gacgtcgaag
    20401 tggtcgctgg gcaggaagtc cagggtgagg tcgccggtga tggtcaggtg cggcagcttg
    20461 tcctggaggt ggcgctcggc gagagtcctc ttggcggcga tcaggatgtc gggcgagatg
    20521 tcgatgccgt agtagtggcc ggcgtcgagg tggtcgatga agcgccagcc gccgcgcagg
    20581 ttgccgcagc cgatgtcgag catgcggtgc tcggggcgca gcccgtgctc ggtgaggtag
    20641 tcgaactgca tctgcccgag cgccagccag cggtcatggg tctgactgcc gaccgcggct
    20701 tcggggttgc ggcgggtgtc ggaggccatg acggcccggt agtagccgac gtggtcgggg
    20761 tgcttcaggc gcagccaggc gtctcggccg gcccggctga ggtatggggc gacgcggccg
    20821 gggtggcgca gggcgtagcc gaccttgtgg gtgagggcgg cgcggttgtt gcgcagtttc
    20881 ttcggtgact tggcgtctgc gggcatggcg aagcgacctc cgtgcaaagg ggccccgggt
    20941 gaggggatga aggggtgcgg gacgaaaggg gtatggggtg ttacaggtga cgcagcatgg
    21001 tcagacgcgg cggcgcagga gcagcatggt gacggccgtg agcaggaggg cgaggccgcc
    21061 gagaagggct gtgtcggtcc actggaaggt ccagtagtcg ctggccgggt tggcctcgta
    21121 gaagcgggcg acgtagccgt gctgggccat gcactccttg agctgggcgc ttgaggggaa
    21181 ggggcagttc attacgtcgt cgtagcggcc ggaggcggtg atcagcccgt agtggccggt
    21241 cgaccacttc tcgtccatgg gtggcttggg gatgctgccg gcgctggtgt aggtgtgcgg
    21301 cgggaccagc aggcgggtcc tgtgcgtcca ctgcagcagg agggtcgtcg cccctgtcac
    21361 caggagggtc agacccatcg cggccagcac ccggcgggcc agcaaaccca gcagtgtgcc
    21421 ggccgccagg ccgaacaggg cggctgcgac gacactcggg cccgagccgc tcagggcggt
    21481 gttctcgtac cagaacaggc cgtaactccg gtccgcggcc ggttgccacc accacgcgaa
    21541 cagccccgcg agcacgccgg agacggccac cgtggtcacc gcggcgagcg ccatccggga
    21601 ggcgaaccac cggccgcggc tcacgccttg ggcgaggacc atgcggtgcg tgcccagttc
    21661 ccggtcgcgg cccagcaggg gcgcgcccca gaagacgccg atgatgacgg gcagcacgat
    21721 gttcagcgtg ccgaggtact tcagcggctc gatgtccagc agcaggggca cgccggtgtc
    21781 ggactgcgtg cagtacagcg gtccggtgcc gcagtggtcg aacagtccgc tgtgcagggc
    21841 gtccagcatg cccgagcggt tgtacgcggc gatcgccgcg gcggtggcca gtgcggccgc
    21901 gccgacgccg gccagcactc gctgctgacg ccaggcgagc cagagggagc cgtgccagag
    21961 agagccggtt cggagggagc cgttcacgcc gccgcctccg tccgcccggc gccggccggg
    22021 cgcagcgtgt cgttggcctg gaggtagccg atcaggatgt cctccagcgt gggccgctcg
    22081 gcgtgccagt cgccgcgcag tggtccctgc tgtcgtatca gggcggtcag ctgtcggcca
    22141 ccggcgcggc ggtggacgac ggtgtgccgt gcggccaggg cgtcggcctg gtcggcgtgt
    22201 cctgtcagta cggtgtggtt ctcgcg
//
