LOCUS       NZ_KQ257863            27466 bp    DNA     linear   CON 02-JAN-2025
DEFINITION  Streptomyces stelliscabiei strain P3825 scf_652_52.1, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ257863
VERSION     NZ_KQ257863.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces stelliscabiei
  ORGANISM  Streptomyces stelliscabiei
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 812938)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Genome sequencing of plant-pathogenic Streptomyces species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 812938)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JUL-2014) Biosciences, University of Exeter, Geoffrey
            Pope Building, Stocker Road, Exeter, Devon EX4 4QD, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001189035.1-RS_2025_01_02
            Annotation Date                   :: 01/02/2025 01:49:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,536
            CDSs (total)                      :: 9,455
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 81
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 482
            CDSs (without protein)            :: 482
            Pseudo Genes (ambiguous residues) :: 0 of 482
            Pseudo Genes (frameshifted)       :: 129 of 482
            Pseudo Genes (incomplete)         :: 407 of 482
            Pseudo Genes (internal stop)      :: 20 of 482
            Pseudo Genes (multiple problems)  :: 69 of 482
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:19:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 312640
            Orig. end                         :: 340106
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ257863.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27466
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..27466
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="RiPP-like"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10216
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10216
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5216](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5216)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    1541..1556
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.48"
                     /tool="antismash"
     gene            complement(1858..4095)
                     /locus_tag="IQ64_RS21510"
                     /old_locus_tag="IQ64_22720"
     CDS             complement(1858..4095)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115096.1"
                     /locus_tag="IQ64_RS21510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22720"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_046912813.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.7e-38, bitscore:
                     126.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATEDTARPPTRGRRKAAPRKPPTPRGGQRAVRTPTVLQMEAVE
                     CGAASLAMVLGHYGRHVPLEELRIACGVSRDGSRASNVLKAARSHGLTAKGMQMDVAAL
                     AEVRAPAILFWEFNHYVVYDGMGRRLGRRGVHINDPGKGRRFVPMEEFDASFTGVVLVM
                     EPGDDFAEGGRRPGVLGAMPARMRGTAGTLPAAVLASLLLVAVGAAVPALSRTYIDMFL
                     IGGQTSLLGVLFGSMGACVLLTVLLTWLQQANLLRGRLISSTLSSARFLRHLLRLPVTF
                     FSQRSPADLVQRLQSNDAVAETLARDLAAAGVDAVVVVLYAVLLYTYDPQLTFVGIAVA
                     LLNVVAMRVVIRLRATRTAKLRADNARLTNTAYTGLQLIETMKATGGEEGYFRKWAGQH
                     ATTLEEQQRLGVPSAWLGVVAPTLATLNSALILWIGGMRAVEGHISVGLLVAFQALVTR
                     FTAPITRLNGVAGRIQDFAADVARLKDVENFRADPLYARPDAAGSTRRLQGHVELENIS
                     FGYSPLDKPLLTGFDLTVGPGQQVALVGGSGSGKSTVSRLLSGLYTPWEGVIRIDGRRL
                     EDIPRGALAASVSFVDQEVFLFEGTVRDNVALWDPSIPDEAVVEALRDAALYDVVTRRP
                     GGIHSRVEQDGRNFSGGQRQRLEIARALVRRPSILILDEVTSALDAETELTVMDSLRKR
                     GCACVVIAHRLSTVRDSDEIVVLRHGTIVERGRHEELLARGGAYAQLVRER"
     gene            complement(4092..4898)
                     /locus_tag="IQ64_RS21515"
                     /old_locus_tag="IQ64_22725"
     CDS             complement(4092..4898)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386622.1"
                     /locus_tag="IQ64_RS21515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22725"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_046912812.1"
                     /transl_table=11
                     /translation="MQFRQQALAKLQSPEELDLPVRFARPQGWLVLSVTVVAMAAASVW
                     AVTGSVASTVGAPAVLTHGQGSYILQSPVAGQVTAVLARQGERLPARAPVVKVATAGGE
                     TVVRSVAAGRVSALAATIGRIIRTGDDVAAIEKVAHADDPLWATVYVPAENAASIPEDA
                     PVDLTVQSAPTRRYGVLRGHVTKVDRAAQTPQSIGAFLGDSRLGEQFTAKGRPVAVTVR
                     LDRKASTESGYRWSSQDGPPFELASMTMATGSIRLADERPIDWLLP"
     cand_cluster    4728..27466
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    4728..27466
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[14727:17466](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(14728..17466)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     gene            complement(5001..5216)
                     /locus_tag="IQ64_RS21520"
                     /old_locus_tag="IQ64_22730"
     CDS             complement(5001..5216)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128984.1"
                     /locus_tag="IQ64_RS21520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22730"
                     /product="hypothetical protein"
                     /protein_id="WP_005484006.1"
                     /sec_met_domain="strepbact (E-value: 7.4e-37, bitscore:
                     121.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTPQVETAEISDAALDAVSGGLSVNAVGTVTGLVDGVAPVSGL
                     VNTAVGTVEGVTGLNTAPVTSLVAGL"
     misc_feature    complement(5187..5202)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.07"
                     /tool="antismash"
     misc_feature    complement(5808..5818)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    complement(5843..5855)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            5979..7421
                     /locus_tag="IQ64_RS21525"
                     /old_locus_tag="IQ64_22735"
     CDS             5979..7421
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994899.1"
                     /locus_tag="IQ64_RS21525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22735"
                     /product="S1 family peptidase"
                     /protein_id="WP_225966967.1"
                     /transl_table=11
                     /translation="MSHKRATKRKAFIAAGGVAALGAAALILPNAMASQTESKDAAPKT
                     LAASDASDLASQLREALGDAFAGAYYDSAEKQLIINVIDGLQIDGDDNDVIVQAQSAGA
                     EVREVENSWSELQKGAATLKAKASVPGTAWAIDPRTNKIQVTADSTVTGENWDTIESAT
                     KSLGTGMATIKKSAGTFKTFLEGGDAIFGGGARCSAGFNVVNAEGAPAFLTAGHCGVVE
                     AEWSEEEGGAPIATVDAATATFPGAGDFALVNYDDPATQAASTVDLGNGQTVDIKAAGE
                     AEVGLQVFRMGSTTGLADGQVTGLEATVNYPEGTVTGLIQTDVCAEPGDSGGSLFTEDG
                     QAIGLTSGGSGDCTVGGETFFQPVTTALAAVGATLGDAGAGAGEEAAGGAGDAAGAGEQ
                     ADGGAAAGAGQEEGAAAAGAGEEEGAAAAGAGEEQGVVGGAGDAGAAAGAGDDAGADQQ
                     HDQGVGDQGAEQQGAEQQGVRQ"
     gene            complement(7634..9778)
                     /locus_tag="IQ64_RS21530"
                     /old_locus_tag="IQ64_22740"
     CDS             complement(7634..9778)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115095.1"
                     /locus_tag="IQ64_RS21530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22740"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_046912811.1"
                     /transl_table=11
                     /translation="MSDVHASAGRTTVETGRVGHPLLSLALASMMDDVGAHSGAVYLLA
                     PDEPVLEMAVMAGLPRSFAAPWERVGLSAPVPVSEAVRGQRLVWVSGEEQMARRYPRIA
                     VVLPYPFALAALPVATRDTTYGAVFLTWPGSHPPELSERERDQLTSACDRLAKRLRRAE
                     EEGRPVLPEPDLSAPSATMVAGTLGTVEAARMVARLPYGMCALDLHGRITFANASTAEL
                     LGIPVSGLLGTQLWVSVPWLNDPAYEDRYRAALMSQHVTSFVALRPPSDWLSFRLYPGS
                     NGLSVRISRARAVAEAEHAARVEGDGPGRLVTIHHVLALASALTEAVGVQDVVELVADE
                     IVPAIGGQALVMYGSRAGRLHVLGHRGYADPHLVERFDGTPLTAPMPGAHALTTGVPAF
                     FESRQQLEHLYPVRQDTPDGLSAWAYIPLIASGRPVGTWVLGYAEPHPFPADERAVLTS
                     LSGLIAQALERALLYDAKHQLAHGLQQALLPHSLPSIPGIEAASRYLPATRGMDIGGDF
                     FDLVLSHGRASAVIGDVQGHNVTAAGLMGQIRTAVRAYTTVGHSPGEVMSSTNRLLIDL
                     GSELFASCLYLRLDPAHGTAVMARAGHPPPLLRRPDGKVRVLDLAGGPLLGIDASATYP
                     TTEVALTPGSVLVLYTDGLIESPGVDIEDALAALGERLSTAGERPLEWLADRLVRETEA
                     AEERADDVALLLLRATGAAG"
     gene            10081..>10581
                     /locus_tag="IQ64_RS21535"
                     /old_locus_tag="IQ64_22745"
                     /pseudo=""
     CDS             10081..>10581
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="IQ64_RS21535"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22745"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHDECLVRSVLAEWLRQEPDLMVHDASWRAAPGRVRSLRPDVCAA
                     DLDCADAVGIPPLGDLRGAGGPAPGLLVLAHAGRPGLLKRAAEAGALGYVDKKGSPRRL
                     VSAIREVARGQRFVDDSLGFGFLKAAEMPFTRRELSVLSLAAEGASVAEIAGSLHLSHG
                     TVRN"
     misc_feature    10504..10506
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10504..12477)
                     /locus_tag="IQ64_RS53395"
                     /old_locus_tag="IQ64_22750"
     CDS             complement(10504..12477)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115094.1"
                     /locus_tag="IQ64_RS53395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22750"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_318787727.1"
                     /transl_table=11
                     /translation="MGDRDERRRTDRPATGAGLPGQSFPPPGLPRRGLRFLRRRARVVV
                     TLVLWSVLEAVQTFLTGYALARALDEGFLAGRAGVGLGWLGVGAGAVVVGAFGTGRVYG
                     CVAGLVEPLRDRLVRGVVGRGVREADGGALSGLTQQVEIARDTFAGLVMVSRSFLFTAA
                     GALVGLFSLAPPLLLVVAPPLIAGVALFLATLRPLARRQETFLVADEALADRLGDVCPG
                     LRDITAAGAEDIVAADTGRRVDAEHRAARALARWGVVRVAALAIGGHLPVVLLLAATPW
                     LLARGVTAGALIGALAYVTQSLLPALQNLVHGLGTSGSRLAVVLRRLLPPGHPPHPPGP
                     PHTSPLPTPCAPSAPAGAPALSLSSVTFAYGSSATPVIDDLSLHIAQGTHLAVVGPSGI
                     GKSTLTGLAAGLLLPRRGTVRLCGEPVPGATARAHRVLIPQEAYVFGGSLAENLAELRP
                     KPVPEEELWGAAEAVGLTQVMVRLGGPAAEVDPRALSAGERQLIALGRAYLSPAPVVIL
                     DEATCHLDPEAEERAERAFARRPGTTLVVVAHRVSSARRADRVLVMDGRSVAHGEHGEL
                     LARSALYRDLVGAWSPVPAPPHPRGGRCSEPALPLRDPDGVDPVARPRLTGDGGHVVAH
                     GPVGKVQAAGDLGHRGTLGGQG"
     gene            complement(12477..14288)
                     /locus_tag="IQ64_RS21540"
                     /old_locus_tag="IQ64_22755"
     CDS             complement(12477..14288)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483996.1"
                     /locus_tag="IQ64_RS21540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22755"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_050398629.1"
                     /transl_table=11
                     /translation="MTTLSEAGAPGPAAASLSLPRSTLRHSGPRCAVLALVAMAATGAN
                     LSLPLALGRALDLLLAGDPGASRRVVWCAGLVLAVAALDAVETVLAGTTSARSTAWLRH
                     RTVGHVLAVGPRAVGRFGPGDLVARLVGNAAQAGTAPATVAALLAALAGPLGAVVALGL
                     IDPFLAVVFLVGAPLLALLLRALARDSSDCVARYQRAQGRIAGGLAEAVAGHRTIAAAG
                     IADRTVARVLGPLPELSREGHRMWRVQGRAAARAAAVAPLLQLSVVATAGVLVTRDRLS
                     VGELLAASRYAVLAAGIGVLVGLVSGLVRGRAGSDRLAEILAEAPTAYGERLLPPPGQG
                     APEGRLELRSVTVRRGGRAVLDGVDLVVPGGTTLAVVGRSGAGKSLLAAVAGRLTDPDE
                     GEVRLDGVPLPELDRRELRRAVTHAFERPALLGESVEDTIAFGVPRPSPARVREAARAA
                     HADAFLRRLPDGYATPCADAPLSGGEVQRLGLARAFARDSRLLVLDDALSSLDTVTERH
                     ITAALLRPTGGSRLIVAHRAATAARADAVAWLDGGRVRAVGPHAELWRTAAYRELFGEG
                     GEEGVSASPGAGGAKAAEDDTPPYGGS"
     gene            complement(14527..14643)
                     /locus_tag="IQ64_RS21545"
                     /old_locus_tag="IQ64_22760"
     CDS             complement(14527..14643)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483995.1"
                     /locus_tag="IQ64_RS21545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22760"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_005483995.1"
                     /transl_table=11
                     /translation="MALLDLQTMEADETTGTGGPSSLSVLSCVSAASITLCL"
     CDS_motif       complement(14584..14643)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQTMEADETTGTGGP"
                     /locus_tag="IQ64_RS21545_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14527..14583)
                     /prepeptide="core"
                     /locus_tag="IQ64_RS21545_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="14.10"
                     /molecular_weight="1627.9"
                     /monoisotopic_mass="1626.9"
                     /core_sequence="SSLSVLSCVSAASITLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQTMEADETTGTGGP"
                     /leader_location="[14583:14643](-)"
                     /alternative_weights="1646.0"
                     /alternative_weights="1664.0"
                     /alternative_weights="1682.0"
                     /alternative_weights="1700.0"
                     /alternative_weights="1718.0"
     gene            complement(14728..17466)
                     /gene="lanKC"
                     /locus_tag="IQ64_RS21550"
                     /old_locus_tag="IQ64_22765"
     CDS             complement(14728..17466)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483993.1"
                     /locus_tag="IQ64_RS21550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22765"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_046915801.1"
                     /sec_met_domain="micKC (E-value: 6.1e-202, bitscore: 668.3,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 9.4e-11, bitscore: 37.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.8e-07, bitscore:
                     25.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEAYALADRHFYETPDRLSAGDRAGAAAPGYATAGRAVPEG
                     WRAARIGDWLTLTPVDDGGRPRPGPTQGWKVHASATRGNADRIAAIVWDYCVPRGIPFK
                     FVPGPHLLHLRNAKYAARDSSGKFVTVYPGDEEQLHLVLRELGDLLKGHDGPYILTDLR
                     WNEGPLYVRYGAFARSFVVDERGTLVPAVRDGAGTLVPDQRKPTFHVPEWVTLPAFLEP
                     QLAARNTTTVGDLPYRIDKALHFSNGGGVYVGTDTRDGRRVVLKEGRPHAGLAADGADA
                     VTRLEREKDALERLAGLGVVPEVRDWFTLGDHRFLVMDFVEGRPLNSCVAERHPLLAPD
                     PQPDAVTAYTAWALHVHRAVEEAVAAVHSRGIVFNDLHVFNIMVAPDDRSVSLLDFEAA
                     APAEDDGRQTVAHPGFLAPPDRTGPDVDRYALACLRLALFLPVTSLFVVEREKAAHLAT
                     VIAEQFPEVPSAFLDEAVAEITRAGGDAGPRLAGTRAPAGDWPLAGPGDWPYSRDSMVK
                     AILASATPERDDRLFPGDVAQFSDGGGLGLAHGAAGVLYTLAEVGAERYEEGERWLLDH
                     TAPVPIGTPLGLYDGLAGVALTLDRLGHRQRALDLVERILAEKWHRLSSDLRGGLAGLG
                     LVLDELARTTGESGLRERAAEAARLLVDRLAEPRPAPPRRRAGLLRGASGPALFLLRRY
                     EATGDPALLASAGEALRQDLECLVEQTNGGLAVDEGWRTMPYLGDGSVGVGMVLDDYTA
                     AAATATDGSRTDGSWTADPRAGASAAAVSGAEDTTAEGTLGVESFAEGFARIRAGVLTA
                     ATYRFYAQPGLFEGRAGMILHLARTGAPRETLTEQIAALGWHSMPYEGQLAFPGNHLMR
                     LSMDLGTGTAGCLLALGAAHADADDATAHLPFLPPLRRRPQ"
     gene            17718..20138
                     /locus_tag="IQ64_RS21555"
                     /old_locus_tag="IQ64_22770"
     CDS             17718..20138
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998776.1"
                     /locus_tag="IQ64_RS21555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22770"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_046915800.1"
                     /transl_table=11
                     /translation="MVSAGAAERGTRTLRAELALKSLGGHLDPHERLHAILEQVLVFTS
                     ASVAAVYLPDGEGQALLLAGSAGVPRNLYGLRDSYPAAGTTPVAEVCRSGRRRWLPSAD
                     LQHDADVRRAHAEEFSLGVLPLRERGCLVAVGDGADAFGPEDRQCLDLLAEAVTSSAPA
                     PPAGPGASFDLAMDSGRVEVDEGLLELFGMGPDDFDGRVETLIALTVPEDLPALMSVVE
                     ADHMSIGDRELEFRILQPSGEQKWLRLRGRILPGGEDRPARLVGTVADASTLRTGRGDV
                     ARIQRLAASLATAGTVRDVSQAVVTALRKPLRADRIALAELEGDRLVVTVLDPPQPEVW
                     PEVWRSEWRSEWPDAPVRTMPTLATALREGRAGIWPAGADLEPALAEVGPGGLAVLPLP
                     AGGRMAGACLIGWDNPHDFGPEERALLTAASGLAGQALMRAHAFDAEHELVGMLQRTLL
                     PRRLPQLPGAVAVARYLPTTAGLEVGGDWYDVIPLPDNHVALVIGDVQGHNAGAATLMG
                     QMRTALRAYAVEGHPPDVVVSHANRLLMDMETDLFATCCYVDIDMEEGSAWYVRAGHIP
                     PVVRHPDGSTEISESEGGPPLGVVMRADFPMSPLRLAPGSLLALTTDGLVESADVDVED
                     GLDHLAAELAAADPAHLGVVADTLLGGANRDDDVALLLVRYDGMALRPQRENWSVWRVP
                     QAVGQARRYTRRVLRRWGVESTADTVLLVVSELVTNALVHTDGRVRLDLTLLADRLRVA
                     VADSSPRTPAKPTVIGWEATGGRGILLVEAVSAAWGTVPVSGGKQVWAEIPLD"
     gene            20302..20817
                     /locus_tag="IQ64_RS21560"
                     /old_locus_tag="IQ64_22775"
     CDS             20302..20817
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430695.1"
                     /locus_tag="IQ64_RS21560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22775"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_046915799.1"
                     /sec_met_domain="Metallophos_2 (E-value: 5.4e-29, bitscore:
                     96.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLLLTTDTHLPQRAKALPERLLAEIAEADVVVHAGDWVDEDTLD
                     LLETRARRLIAVYGNNDGPALRARLPEVAHAELAGLRLAVVHETGPAQGREPRCAARFP
                     GTDVLVFGHSHIPWDTTTATGLRLLNPGSPTDRRRQPHCTYMTATAQDGGLTDVRLHRL
                     PPRTRPSS"
     gene            complement(20839..21978)
                     /locus_tag="IQ64_RS21565"
                     /old_locus_tag="IQ64_22780"
     CDS             complement(20839..21978)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483988.1"
                     /locus_tag="IQ64_RS21565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22780"
                     /product="XdhC family protein"
                     /protein_id="WP_046915798.1"
                     /transl_table=11
                     /translation="MREVLPALGAWYAAGSPFGLATVVAVSRSTPRGPGAAMAVGPGDE
                     VVGGVSGGCVEGAVFELAREVVASGEARLETFGYSDEDAFAVGLTCGGEITLLVRRVTV
                     AEDPAFGRVAESVGTGHPVTVATVVDGPAPRGATLAVWPDAAPDGSPAHGTVGTLGSAG
                     LDVAVAADARGELAQGVTGQRHYGPHGERREDSVTVFLHSFAPQPRMLVFGAIDYAAAV
                     ARIGDFLGYRVTVCDARPVFATPKRFPAAVEVVVDWPHRYLRGTATDDRTVICVLTHDP
                     KFDGPLLQEALRRPAAYVGAMGSRRTHDDRARRLREAGLGAAELSRLRSPVGLDLGART
                     PEEVAVSVAAEIVALRWGGSGVPLTATTGVIHPPPDPSR"
     misc_feature    complement(22067..22078)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.03"
                     /tool="antismash"
     gene            22201..>23895
                     /locus_tag="IQ64_RS21570"
                     /old_locus_tag="IQ64_22785"
     CDS             22201..>23895
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483987.1"
                     /locus_tag="IQ64_RS21570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22785"
                     /product="elongation factor G"
                     /protein_id="WP_233443483.1"
                     /transl_table=11
                     /translation="MSRTLNLGILAHVDAGKTSLTERLLHTVGVIDEIGSVDEGSTRTD
                     TLALERRRGITIKSAVVSFAIDDLTVNLIDTPGHPDFIAEVERVLDVLDGAVLVVSAVE
                     GVQAQTRVLMRTLRRLRIPTLIFVNKIDRRGARHQDLLESIAARLTPGIVPMGEVAGLG
                     TPEAHFLPYDPLPPRLLELLAEYDDDLLAAYVDDGTAVPETRLRAALAARTGGSLVHPV
                     FHGSAITGSGIAELVDGIRELLPSTDADHGGDTAGGGDGEAAAPPSGTVFKVERGPAGE
                     KIAYVRMFDGTVRVRDRLAFRDGAREGKVTAISVFEGGADVRATAVSAGRIARLWGLAD
                     IRIGDTVGVPRERAAAAHGHHFAPPTLETVVLPARAEDGAALHLALTQLAEQDPLIGLR
                     HDELRREISVSLYGEVQKEVVQATLADEYGLDVTFRETTTICVERLAGVGAAVEFNKKD
                     GNPFLATVGLRVEPAPAGSGVAFRLEVELGSMPYAFFKAVEDTVRETLEQGLHGWRVPD
                     CTVTMTHSGYSPRQSHAHQGFDKSMSSTGADFRGLTPLVLTDALRRGG"
     misc_feature    complement(22248..22266)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.4"
                     /tool="antismash"
     assembly_gap    23896..23920
                     /estimated_length=25
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <23921..24192
                     /locus_tag="IQ64_RS51230"
                     /pseudo=""
     CDS             <23925..24192
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483987.1"
                     /locus_tag="IQ64_RS51230"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="GTP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="PVLAALRAVPRETRTSGAAVRLEGLVPAAGVHALEQRLPGPTNGE
                     GELETAFDHYAPVGRAAVPSRPRTDLNPLDRKEYLLHLTRRTGV"
     misc_feature    24331..24342
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.28"
                     /tool="antismash"
     gene            24418..26283
                     /locus_tag="IQ64_RS21575"
                     /old_locus_tag="IQ64_22795"
     CDS             24418..26283
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380311.1"
                     /locus_tag="IQ64_RS21575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_22795"
                     /product="endoglycosylceramidase"
                     /protein_id="WP_225966968.1"
                     /transl_table=11
                     /translation="MSRLRTRLLGVLVLVTGFLTTAGPTQPASALTDDLWFDSQAAATL
                     TVEGGRFKDGLGREVVLRGYNVSGETKLKENNGLPFASVADARKSATALRALGGGNSVR
                     FLLSWAYAEPVRGQVSTSYLAAATAQMGAFLDAGIRVYPDFHQDLYSRWLFDSDSWYTG
                     DGAPKWAVDLGNYPDEYCGICPFWGQNITSNAAVTKSTYDFWHNTYGVQDSFLDTAQKT
                     MAYVKSNLTSAQFQGVVGFDPWNEPHPGVLDSGQTSRTWEKDVLWPFYVKFRSRMDAAG
                     WQAKPAFVEPNLFWNANIDFQKQEGGLLDAGTIGPRYVFNTHFYDQKAISGVFMWGKAE
                     NGQYVNDFGTVRDRAAAGGTTAVVSEFGHPLSGSVSDKAPTVYKAMYQALDSRVKGVDW
                     WTKPASSGPVLSGSQWQWDIYWGRHHELMNDNPDKVQAEADGWNGEDLSAVRVDDSGTA
                     VLRQDARMLDRIYPSATAGSTVAFTYEDRSRDGSTTLTWNPVPSSLPNVSSLVGSGQYS
                     LLVWRSDGSTEPTELHLPASFPTASTTVVSDLGVTAAPPAYTTSTPIAAAKEPGGTGSR
                     RLLLTAADTGKLHYALVTNGATAPSAAQLGAARTELSNWLTARFS"
ORIGIN
        1 cccagcacgg tgttgaggtt cttgatcccg ccgaccttct gctgcagctc ccggctgcgc
       61 gcgaactcgc ccgcccaggc cgcgtacgcg tagttctcgg cggcggccac ccgcagcttc
      121 ggcaggcccc gcagggtctg gtacgcctgg ttgttcagct tgttgcccag caccaccaga
      181 tggcgctgcc agcggacctg ccacaggccg aggcccagga acacggcggc cacgatcacc
      241 agcatgccga tcgccgccag ggccatcggc acgctgaacc agagcagcag accgaggttc
      301 acggcaccga tcgtcaccga ctgcgcgacc accgggccga ccccggccag ggtgcggcgg
      361 atcgcgctga tgcccatggc cgcgccggcc agctcaccgg tcgaacgcga ggcgaagaac
      421 gtcgtgggga gccgcaacag gcggtcccag acggcgggtt ggagcgtcgc ctcgatccgg
      481 ccctccatcc ggaggatcgt caggttctgg agcagcagga acgcggccga caccacactc
      541 gcgagcatga tcgccagaca gacccgcacg atcaggtcct cctgcgcctt cggcacgtac
      601 tcgcccagga tcgtgccggt cgcgaccggc acgagcgagc cgagcacgac cgtcaccagg
      661 ccgctcagca gcaggcccgt cagatcgcca ccggtgccgt ggaggctgaa ccgcatcagc
      721 cgcagcgggg tcagcgcccg ttcgggcaga ggccggtaga acatcacggc acgcggctcg
      781 aactccgccg cgttcgcctt ctcgaccggc gtctcccggc cggacgacgg ctgcacggcc
      841 acatagcccc cgcgccgcca cagcagcgcc accggcgcgc cggacagggc gcgatgcccg
      901 accagcgggc ccacgttctc ccgccaccag ttcccggcga gacggacggc acggacccgg
      961 acccgggaag cgagcgcgat acgttccacc gggtcgagcc ggtcgctctc ggtgccgctc
     1021 tgcgccggct ccgagagcgt gatgccggcc gtccgcgcga cgagcacaca ggccgcgtac
     1081 gtggcgtcgg cgtcggcggc cgtggcgggc cgcttcgcgg aggacctgcc gatggaggcg
     1141 agcagcgtgc ggtcggcctg ggcgcgcacc gcctcaccgg ccttgatccc ggcggccgta
     1201 cggtcctcgt gggtgcgctc cagctgctcg atccagcggt ccagcgtggc cagcagccgg
     1261 aactgctggt cgaccatgct ctgccagacc cccgggtcca tcagcaggtc ggccgccgcc
     1321 tgcgcgccgt acaacgatcc gtactggacg ctgccgggcg gcacccgcat ccagaacacg
     1381 tcgtcgtcgg tgggcgccgc ggcctgctcg gtggccatcg gcgcctggaa gaggatggac
     1441 aggccccggc cgacgcccag ggcgagggcg tgttcgaggg ggctcgtccg gggaggcacg
     1501 agctgcggat tgccccacgc gtcgtacgac caggtctcgg tgcccccttg ggggtacagc
     1561 tcacgcaggc cgatgcgccg taccacgcag tcgcgcgacg gccgggccac cagggtgtgc
     1621 tggggcccgg cgaccggacc gagcagcagc gcgcccgctt cgagacggcc caggtggtgc
     1681 cagtggccct gccggccggc gtcgaccgcg aacaggtcca gcgcgccgga cgccaccagc
     1741 cacagggtct gcgggccttc gaggtcgagc cgggtgtggc cggcgcagtc gaggggcgtg
     1801 cccagcgcgc cgagcgcgcc gaggacgagg tcgccctcct ggggtacggc ggtcatctca
     1861 tcgctccctg accagttggg cgtacgcgcc gccgcgtgcc agcagttcct cgtgccggcc
     1921 ccgctccacg atcgtgccgt gccgcaggac gacgatctcg tcgctgtcgc ggaccgtgct
     1981 gagccggtgg gcgatcacca cacaggcgca gccgcgcttg cgcagactgt ccatgacggt
     2041 cagctcggtc tccgcgtcca gcgcgctggt cacctcgtcg aggatgagga tgctgggtct
     2101 gcggaccaac gcccgcgcga tctccagccg ttggcgctga ccgccggaga agttccgtcc
     2161 gtcctgctcg accctgctgt ggatgccgcc cggacggcgg gtcaccacgt cgtacagggc
     2221 cgcgtcccgc agcgcctcca cgacggcctc gtccgggatc gaggggtccc acagggccac
     2281 gttgtcgcgg accgtgccct cgaagaggaa gacctcctgg tcgacgaagg agaccgaggc
     2341 ggccagtgct cccctcggga tgtcctccag acgccggccg tcgatccgga tcaccccctc
     2401 ccagggggtg tacaggccgg agagcagccg ggacaccgtc gacttgccgc tgcccgagcc
     2461 gccgaccagc gccacctgct gaccggggcc gacggtgagg tcgaagccgg tgagcagggg
     2521 cttgtcgagg gggctgtagc cgaaggagat gttctccagc tccacatgcc cctgcagcct
     2581 gcgggtggac ccggcggcgt ccgggcgggc gtacagcggg tcggcccgga agttctcgac
     2641 gtccttgagg cgggccacgt ccgccgcgaa gtcctggatg cggcccgcga cgccgttgag
     2701 acgggtgatc ggcgcggtga accgggtgac cagggcctgg aaggccacca gcaggcccac
     2761 ggagatatgg ccctcgaccg cccgcatgcc gccgatccag aggatgagcg cgctgttgag
     2821 cgtggcgagg gtcggggcga cgacccccag ccaggcgctc ggcacaccga gccgctgctg
     2881 ttcctccagc gtggtggcgt gctgcccggc ccacttgcgg aagtagccct cctcgccgcc
     2941 ggtcgccttc atcgtctcga tcagctgcag accggtgtac gccgtgttgg tcagccgggc
     3001 gttgtcggcg cgcagcttcg ccgtacgggt cgcgcgcagc cggatcacca cccgcatcgc
     3061 caccacgttc agcagcgcca ccgcgatgcc gacgaaggtg agctgcgggt cgtaggtata
     3121 gaggagtacg gcgtagagga cgacgacgac cgcgtccacg ccggcggcgg cgaggtcgcg
     3181 ggccagggtc tcggcgaccg cgtcgttgga ctgcagccgc tggacgaggt cggcggggct
     3241 gcgctgggag aagaaggtga cgggcagtcg cagcaggtga cgcaggaagc gggcgctgga
     3301 cagggtggag gagatcagac ggccgcgcag caggttggcc tgttgcagcc aggtcagcag
     3361 gaccgtcagc agcacgcacg cgcccatcga cccgaacagc acacccagca gggaggtctg
     3421 gccgccgatc aggaacatgt cgatgtaggt gcggctcagc gcgggcaccg cggcgccgac
     3481 cgccaccagc agcaggctgg cgaggacggc ggcgggcagg gtgccggccg tgccgcgcat
     3541 ccgggcgggc atggcgccga ggacaccggg tctgcggccg ccctcggcga agtcgtcgcc
     3601 gggctccatc accaggacga ccccggtgaa ggaggcgtcg aactcctcca tgggcacgaa
     3661 ccggcgcccc ttgccggggt cgttgatgtg cacaccgcgt cggccgaggc ggcgccccat
     3721 gccgtcgtag acgacgtagt ggttgaactc ccagaagagg atcgccggcg cccgcacctc
     3781 ggcgagggcg gccacgtcca tctgcatgcc cttggccgtc agcccgtgac tgcgggccgc
     3841 cttcaggacg ttgctggcac gggagccgtc ccgggagaca ccgcaggcga tgcgcagttc
     3901 ctccagcggt acgtgccgtc cgtaatggcc gaggaccatg gcgagggagg cggcgccgca
     3961 ctccacggcc tccatctgca ggacggtcgg ggtgcgcacg gcccgctgcc cgcccctggg
     4021 tgtcgggggc ttgcgcgggg cggccttgcg tctgccgcgc gtcggcggcc gggcggtgtc
     4081 ctcggtcgcg gtcacgggag cagccaatcg atcggacgct cgtcggccag ccggatcgaa
     4141 cccgtggcca tggtcatgga ggccagctcg aacggcggcc cgtcctgcga ggaccacctg
     4201 tagcccgact ccgtcgaggc cttccggtcc agccgtacgg tgacggccac cggccggccc
     4261 ttcgcggtga actgctcgcc cagccggctg tccccgagga acgcgccgat cgactgcggg
     4321 gtctgcgcgg cgcggtccac cttcgtcaca tggccgcgca gcacgccgta ccggcgggtg
     4381 ggcgccgact gcacggtcag gtccacgggg gcgtcctcgg ggatcgaggc ggcgttctcg
     4441 gcggggacgt acaccgtcgc ccagagcggg tcgtcggcgt gggcgacctt ctcgatcgcc
     4501 gcgacgtcgt cgccggtgcg gatgatccgg ccgatcgtcg cggcgagcgc ggagacccgg
     4561 ccggccgcga cggaccgtac gacggtctcg ccgccggcgg tggcgacctt gacgacgggg
     4621 gccctggcgg gcagccgctc gccctgtcgc gcgagcacgg cggtgacctg gccggccacc
     4681 gggctctgca ggatgtagct gccctgcccg tgggtgagga cggcgggagc gccgaccgtg
     4741 gaggcgacgg aacccgtgac ggcccacacg gacgcggcgg ccatggcgac caccgtcacg
     4801 gacagcacca gccagccctg cgggcgggcg aaacgcaccg gcaggtcgag ttcctccggt
     4861 gactggagct tggcgagggc ctgttggcgg aactgcacgg gacttccctc acctgcgcga
     4921 ctcgggagga ggacgttcga gcaccggaga gtcccggaac ctgtcaggtg gttccgggac
     4981 tcagcggcac aggggctcga tcagagaccg gcgaccaggc tcgtgaccgg ggcggtgttc
     5041 agaccggtga caccctcgac ggtgccgacg gccgtgttca ccaggccgga gaccggagcg
     5101 acgccgtcca ccaggccggt gacggtgccg acggcgttga cggacaggcc accggaaacg
     5161 gcgtcgaggg cggcgtccga gatctcggcg gtctcgacct ggggggtgga gttcatgggg
     5221 gaacttccct tcgtatagct cttcataggg gggagcggcc cccttctggg gacagaacga
     5281 cggccgcgca cggggatgcc cgctctcgtc tccgagagtc cggcggcccc cgcggtgcga
     5341 tggactaaag cagatcgccg ccgcgcatct ccaatcaaca tggcccccca ccagcgcact
     5401 tggtgaccat ggcggtttat ccgtgcaggg ccgcgcacgt gttggggcca gcttcttcac
     5461 accgatcccg gcatcgtcat aggtcgttca tggcccgccg gaaagcgaaa gggacagtcc
     5521 cgccccaaag gcacggcacc cgcgccggcc ctgtgcagaa ccgtcgtcga ccgtgacccc
     5581 gccgagtatt cggtgtggag attcgccgaa gccggtttcc ggtccgacat cgacgacgga
     5641 gggccaccgg ccggtcgccg aatgtgcggg gccgggcagt cggccgcccc gcccgcgacg
     5701 gatcgcgaaa gtgcgtccga ggagggccgg aggggtccgg aggagggctg cagccgtcgc
     5761 cgcggagggg ctccgcggcc tcgacgggcc cgtgcgtgcg ggaagtcgtg acatggcggg
     5821 cgaactgggg gcgtagcgcg ctttgcgaaa tggaagaccg gaatcttttt gcggagcgtt
     5881 gaacacccca ccggaaccat ccgtaccaac tggcaaccag gcgcccccag ttcacccgca
     5941 cgacggcggt acggaccccg tccccaggag gtcaagagtt gagtcacaaa cgagccacca
     6001 agcgtaaggc gttcatagcc gcaggcggcg tggcggcgct cggcgcggca gccctcatcc
     6061 tgcccaacgc gatggcgtcc cagacggagt cgaaggacgc cgccccgaag acgctcgccg
     6121 cgagtgacgc ctcggacctc gcctcccagc tccgggaggc actcggtgac gcgttcgcag
     6181 gcgcgtacta cgactcggcc gagaagcagc tcatcatcaa cgtcatcgac ggcctccaga
     6241 tcgacggcga cgacaacgac gtgatcgtcc aggcccagtc ggccggtgcg gaggtccgtg
     6301 aggtcgagaa cagctggtcc gagctgcaga agggcgcggc gacgctgaag gcgaaggcca
     6361 gcgtccccgg caccgcctgg gcgatcgacc cccgcaccaa caagatccag gtcaccgccg
     6421 actccacggt cacgggcgag aactgggaca ccatcgagtc ggccaccaag tcgctcggca
     6481 cgggcatggc gaccatcaag aagtccgccg gcaccttcaa gacgttcctg gagggcggcg
     6541 acgccatctt cggcggcggc gcgcgctgct cggccggctt caacgtcgtc aacgccgaag
     6601 gcgccccggc cttcctgacc gccggtcact gcggagtcgt cgaggccgag tggtccgagg
     6661 aggagggcgg cgccccgatc gccacggtgg acgccgcgac cgccaccttc cccggcgccg
     6721 gtgacttcgc cctggtcaac tacgacgacc cggcgaccca ggcggccagc acggtcgacc
     6781 tcggcaacgg ccagacggtc gacatcaagg cggccggcga ggccgaggtc ggcctccagg
     6841 tcttccgcat gggcagcacc accggtctcg ccgacggcca ggtgaccggt ctcgaagcca
     6901 cggtgaacta ccccgagggc acggtcaccg gtctcatcca gaccgacgtc tgcgccgagc
     6961 ccggcgacag cggcggctcg ctgttcaccg aggacggcca ggccatcggc ctgacctccg
     7021 gcggcagcgg cgactgcacg gtcggcggcg agaccttctt ccagccggtc accaccgccc
     7081 tcgcggcggt cggcgcgacc ctcggcgacg cgggcgcggg cgccggtgag gaggccgccg
     7141 gcggtgccgg tgacgccgcg ggtgccggcg agcaggccga cggcggtgcc gccgccggtg
     7201 ccggtcagga agagggcgcg gccgccgcgg gcgcaggcga ggaagagggc gcggccgcgg
     7261 ccggtgcggg cgaggagcag ggcgtcgtgg gcggtgccgg tgacgccggc gccgcggccg
     7321 gtgccggtga cgacgccgga gcggaccagc agcacgacca gggtgtcggc gaccagggcg
     7381 ccgagcagca gggtgccgag cagcagggcg tccggcagta ggcggacacc ccccgcacgt
     7441 ggacgacggc ccgggctcag cggccactga cccccggccc gtcaccccac gacccgcctg
     7501 ccggccccac cccagcggtg cggccggcag gtggaacggt ccggccctcc ggcgggaggg
     7561 ccggaccgct ttcgtccgtc cgccgcgctt tcgtccgtac ggcgaagacc cccgacccgc
     7621 ggcacgcggg cggtcacccg gcggcgcccg tggcccgcag caacagcagg gccacgtcgt
     7681 ccgctcgctc ctccgccgcc tccgtctccc gtacgagacg gtcggcgagc cattccaggg
     7741 gccgctcccc ggccgtcgac agccgctccc cgagagcagc cagcgcgtcc tcgatgtcca
     7801 ccccgggcga ctcgatcagc ccgtcggtgt acaggaccag caccgacccc ggtgtcagcg
     7861 ccacctcggt cgtcggatac gtcgccgacg cgtcgatgcc gagcagcgga ccaccggcga
     7921 ggtccagcac ccgcaccttc ccgtccggcc ggcgcagcaa cggcggcgga tgccccgccc
     7981 gcgccatgac ggccgtcccg tgcgccgggt cgagccgcag atacagacag ctcgcgaaca
     8041 gctccgaacc caggtcgatc agcagccggt tggtgctgct catcacctcc cccggtgagt
     8101 gcccgacggt cgtgtacgcg cggaccgccg tacggatctg ccccatcagg cccgccgccg
     8161 tcacgttgtg cccctgcacg tccccgatca cggcggaggc ccgcccgtgc gagaggacca
     8221 ggtcgaagaa gtcgccgccg atgtccatgc cccgggtggc gggcagatag cgggaggcgg
     8281 cctcgattcc cgggatcgac ggcagcgagt gcggcagcag ggcctgctgc agaccgtgcg
     8341 cgagctggtg cttggcgtcg tacagcagcg cccgctccag ggcctgggcg atcagcccgc
     8401 tgaggctggt cagcaccgcg cgctcgtcgg cggggaaggg atgcggctcc gcgtacccga
     8461 gcacccaggt acccaccggc cgccccgagg cgatcagcgg gatgtacgcc caggcgctga
     8521 gcccgtccgg ggtgtcctgc cgcaccgggt acaggtgctc cagctgctgc cgggactcga
     8581 agaaggccgg caccccggtg gtcagggcgt gcgccccggg catcggcgcg gtgagcgggg
     8641 tgccgtcgaa gcgttccacg aggtgcgggt cggcgtagcc gcgatggccg agcacatgca
     8701 gccgcccggc acgcgagccg tacatcacga gggcctgccc gccgatggcc gggacgatct
     8761 cgtcggcgac cagttccacc acgtcctgca cgcccaccgc ctcggtgagc gcgctcgcca
     8821 gcgccagtac gtggtggatg gtcaccaggc ggcccggccc gtcgccctcc acccgcgcgg
     8881 cgtgctcggc ctcggcgacc gcgcgggccc gcgagatccg tacgctcagc ccgttcgacc
     8941 ccgggtacag ccggaacgac agccagtcgc tcggtggccg gagcgccacg aacgacgtca
     9001 cgtgctgact catcagcgcc gcccggtacc ggtcctcgta cgccggatcg ttgagccacg
     9061 gcaccgacac ccacagctgg gtgcccagca gaccgctcac cgggatgccg agcagttcgg
     9121 ccgtggacgc gttggcgaag gtgatccgcc cgtgcaggtc gagcgcgcac atgccgtacg
     9181 gcagccgcgc caccatccgc gccgcctcca ccgtgccgag cgtccccgcg accatggtcg
     9241 ccgacggcgc cgacaggtcc ggctccggca gcaccgggcg gccctcctcc tccgcgcgcc
     9301 gcagccgctt ggcgagccgg tcgcaggccg aggtcagctg gtcccgctcg cgttcgctca
     9361 gctccggcgg gtgggagccg ggccaggtga ggaagacggc gccgtaggtg gtgtcgcggg
     9421 tcgccaccgg cagcgcggcc agggcgaacg gatagggcag gaccacggcg atccggggat
     9481 agcggcgggc catctgctcc tcgccgctga cccacaccag acgctgtccc cgcaccgcct
     9541 cggagacggg gacgggggcg ctcagcccca cccgctccca cggcgcggcg aacgacctcg
     9601 gcagtcccgc catgaccgcc atctccagga ccggctcgtc cggcgccagc agatacaccg
     9661 ccccggagtg ggccccgacg tcgtccatca tcgaggccag cgccagggag agcagcggat
     9721 ggccgacacg gcccgtctcc acggtcgtcc gccccgcgga cgcatggacg tcggacatgc
     9781 ccaccacctc ctcgcacggc cgcgcgacgg ttccagggtc caggctcctc ctagggggcc
     9841 gcccacgcac ggcgagcgcc cgcccggacg aaccgccgta ccccctcccg cccggcccat
     9901 gccccctcgc ctgatgcgcg cgctcgcgca cgggcgccgc gagtgcgccc ccgcgccccc
     9961 caatggctgg ttctccgtgc cctggcgtgt ggtcggggac gccgacaatg ggcacgcgct
    10021 tggggcggag gacatcggtg ggccgggagg cggagggcga acgtgatcgg ggtactgctc
    10081 gtgcacgacg aatgtctggt caggtcggtc ctcgcggagt ggctgcgcca ggaacccgac
    10141 ctgatggtgc acgacgcgtc ctggcgcgcg gcgccgggcc gtgtccggtc cctgcggccg
    10201 gacgtctgcg cggcggacct ggactgcgcc gacgcggtcg gcatcccgcc cctcggcgac
    10261 ctgcgcggcg cgggcggccc cgcccccggg ctgctggtcc tggcccacgc gggcagaccc
    10321 ggcctgctga agcgcgcggc ggaggccggg gccctcgggt acgtggacaa gaagggctcg
    10381 ccccggcggc tggtgtcggc gatacgcgag gtcgcccggg ggcaacgctt cgtcgacgac
    10441 tccctcggct tcggattcct caaggccgcc gagatgccgt tcacgcgccg cgagctgagc
    10501 gtgttatccc tggccgccga gggtgcctcg gtggccgaga tcgccggcag cctgcacctt
    10561 tcccacggga ccgtgcgcaa ctacatggcc gccatcaccc gtaagacggg ggcgcgcaac
    10621 aggatcgacg ccatccggat ctcgcagggg gagggctggc tctgaacagc gcccgccgcg
    10681 cgggtgcggc ggggccggta cgggggacca ggcgccgacc aggtcccggt agagcgccga
    10741 gcgggccagc agctcaccgt gctccccgtg ggcgacggac cgcccgtcca tgaccagcac
    10801 ccggtcggcg cggcgggccg agctgacgcg atgggcgacc accacgaggg tcgtgcccgg
    10861 ccgccgggcg aaggcccgtt ccgcgcgctc ctccgcctcc gggtccaggt gacaggtcgc
    10921 ctcgtcgagg atcacgaccg gcgccggcga caggtacgcc cgaccgagcg cgatgagctg
    10981 ccgctccccg gcggacagcg cgcgcgggtc gacctcggcg gccggaccgc ccagccggac
    11041 catcacctgg gtgagcccca cggcctccgc ggcgccccac agctcctcct cgggcacggg
    11101 tttcggccgc agttcggcga gattttcggc gagggatccc ccgaagacgt acgcctcctg
    11161 cggaatgagc acccggtgtg cacgcgctgt ggcgccgggt accggctccc cgcacaagcg
    11221 gacggtgccg cgccggggga gcagcagacc cgcggcgagc cccgtgaggg tggacttgcc
    11281 gatgccgctg gggccgacga cggccaggtg cgtgccctgg gcgatatgga ggctgaggtc
    11341 gtcgatgacg ggggtggcgg aggagccgta ggcgaaggtg accgaggaga gggagagggc
    11401 gggagcgccg gcgggagcgg acggggcgca cggggtgggg aggggcgagg tgtgcggcgg
    11461 gccgggaggg tggggcgggt ggcccggcgg aagcaggcgg cgcagtacca ccgcgagccg
    11521 ggagccgctg gtgccgaggc cgtggaccag gttctggagg gcgggcagga gcgactgggt
    11581 gacgtaggcg agggcgccga tcagggcgcc cgcggtgacg ccccgggcca ggagccaggg
    11641 tgtggcggcc agcagcagga cgacgggcag gtggccgccg atcgcgaggg cggcgacgcg
    11701 tacgacgccc cagcgggcca gcgcgcgggc ggcccggtgc tcggcgtcga cgcgacggcc
    11761 ggtgtcggcg gcgacgatgt cctccgcgcc ggccgccgtg atgtcgcgca gcccggggca
    11821 gacgtcgccg agccggtcgg cgagcgcctc gtcggcgacg aggaaggtct cctgccggcg
    11881 ggccagcggc ctgagcgtcg ccaggaagag ggccacgccg gcgatcagcg ggggcgccac
    11941 cacgagcagc agcggcggcg ccagtgagaa gagtccgacg agcgccccgg cggcggtgaa
    12001 caggaacgag cgcgagacca tcaccagccc ggcgaaggtg tcccgggcga tctccacctg
    12061 ctgggtgagc ccggacaggg caccgccgtc cgcctcccgc accccccgcc cgaccacccc
    12121 gcgcaccagc cggtcccgca acggctccac cagccccgcc acacacccgt acacccgccc
    12181 ggtgccgaac gccccgacga ccaccgcccc cgccccgacc ccgagccacc ccagcccgac
    12241 gcccgcccgc ccggccagga acccctcgtc gagggcccgc gccagcgcgt accccgtcag
    12301 aaacgtctgc accgcctcca gcacggacca cagcaccagc gtgacgacga cccgcgcccg
    12361 gcgccggaga aagcggaggc cgcgacgggg gaggccgggt ggggggaagg actgtcccgg
    12421 caggccggct ccggtggccg gccggtcggt cctacgacgt tcgtcccggt cgcccatcac
    12481 gaaccgccgt acggaggcgt gtcgtcctcg gcggccttcg ccccgcccgc gccgggcgag
    12541 gcggagacgc cctcctcgcc cccctctccg aacagctccc ggtacgccgc cgtccgccac
    12601 aactcggcgt ggggccccac cgcccggacc ctccccccgt ccagccaggc caccgcgtcc
    12661 gcgcgggcgg ccgtggcggc gcggtgggcg acgatcaggc ggctgccgcc ggtggggcgc
    12721 agcagcgcgg cggtgatgtg gcgttcggtg acggtgtcga ggctggagag cgcgtcgtcg
    12781 agcacgagga gacggctgtc gcgggcgaac gcccgggcga gaccgaggcg ttggacctcc
    12841 ccgcccgaca ggggggcgtc ggcgcacggg gtggcgtagc cgtcggggag gcgccggagg
    12901 aaggcgtcgg cgtgcgcggc gcgggcggct tcccggacgc gggcggggga gggccggggg
    12961 acaccgaagg cgatggtgtc ctccacggac tcgcccagca gggccgggcg ttcgaaggcg
    13021 tgggtgaccg cccggcgcag ctcccggcgg tccagttcgg gcaggggcac cccgtcgagc
    13081 cgtacctctc cctcgtccgg gtccgtgagc cgccccgcga cggccgcgag cagcgacttg
    13141 cccgccccgg accggcccac gacggccagg gtggtcccgc ccggtacgac gagatcgacc
    13201 ccgtccagca cggcgcgccc cccgcgccgg acggtcacgg agcgcagttc cagccgcccc
    13261 tcgggggcgc cctgccccgg cggcgggagc agccgttcgc cgtacgcggt cggagcctcg
    13321 gccaggatct cggcgagccg gtccgacccc gcccggccgc ggacgaggcc cgagacaagg
    13381 ccgaccagga cgccgatgcc cgcggccagc accgcgtagc gggacgcggc gagcaactcg
    13441 cccacggaca gacggtcccg ggtcaccagg acgcccgccg tggcgacgac ggagagctgc
    13501 agcaggggtg ccacggcggc cgcccgcgcg gcggcccggc cctggacccg ccacatccgg
    13561 tgcccctcac gggagagttc gggcaggggg ccgaggacgc gggcgacggt ccggtcggcg
    13621 atgcccgcgg cggcgatcgt gcggtgtccg gcgacggcct cggccagacc gcccgcgata
    13681 cgcccctggg cccgctgata acgcgcgacg cagtcggagg agtcccgggc gagcgcgcgc
    13741 agcagcagcg cgagcagcgg cgctccgacc aggaacacca ccgcgaggaa cgggtcgatc
    13801 aggcccaggg ccaccacagc gcccaacggc cccgcgagcg ccgcgagaag cgcggcgacg
    13861 gtggcgggcg ccgttcccgc ctgggccgcg ttcccgacga gccgggccac caggtccccc
    13921 ggcccgaacc ggccgacggc ccgcggcccc accgccagga cgtgtccgac cgtgcggtgg
    13981 cgcagccagg cggtggaccg ggcgctcgtg gtcccggcga ggacggtctc gaccgcgtcc
    14041 agggcggcga cggcgagaac cagcccggcg caccacacca cccggcgcga ggcgcccggg
    14101 tcgccggcca gcagcagatc cagggcccgc ccgagggcga gcggcagcga caggttcgcc
    14161 cccgtcgcgg ccatggccac gagtgccagg accgcacaac gggggccgga gtgccggagg
    14221 gtggagcgcg gcagggagag ggacgcggcg gccgggccgg gggcgccggc ttcggagagg
    14281 gtcgtcatac ccgtcctgac gtgggatgac cgggtgaccg ggtgaccggg atgaccggac
    14341 gaaggggcgg aggcggaggc gtggacggag gtcgcgcgac cgccgtgtgg cagtggcgcg
    14401 gaggtgagtg agccccggac ggcccctccc caggcagggg agaggaaccg tccggagccg
    14461 tcggcgcggc tcagccgccg tgccggtccg acggacgccc gggatcaccc ggacgccccg
    14521 gccgggtcag aggcagagcg tgatgctggc cgcgctcaca caggacagaa cgctcaggga
    14581 gctgggcccg ccggtgccgg tcgtctcgtc ggcttccatc gtctgcaggt cgaggagtgc
    14641 catgtcgatt cctttcggtc gtggcccgtt caggggcctt ggggacgggg gtgttgcgtc
    14701 acgactccgc cgggtggcgg aaccgcgtca ttggggccgc cgtcggagcg gcggcaggaa
    14761 cggaaggtgt gccgtggcgt cgtcggcgtc agcgtgtgcc gcgccgagcg ccagcaggca
    14821 acccgccgtc ccggtaccga ggtccatgga gagccgcatc aagtggttgc cggggaaggc
    14881 cagttgcccc tcgtacggca tcgagtgcca gccgagcgcc gcgatctgtt ccgtcagcgt
    14941 ctcgcggggg gcgcccgtcc gggcgaggtg caggatcatc ccggcgcggc cctcgaacag
    15001 ccccggctgc gcgtagaagc ggtaggtcgc ggcggtcagg acgcccgcac ggatccgggc
    15061 gaagccctcc gcgaagctct ccacaccgag ggttccctcg gccgtggtgt cctccgctcc
    15121 ggagacggcc gccgcggagg cgcccgcccg ggggtcggca gtccacgagc cgtcggtcct
    15181 ggagccgtcc gtcgcggtgg cggccgcggc cgtgtagtcg tcgagcacca tgccgacgcc
    15241 cacgctcccg tcgccgagat acggcatcgt ccgccatccc tcgtcgacgg ccagaccgcc
    15301 gttcgtctgc tcgaccaggc actccaggtc ctgccgcagc gcctcaccgg ccgaggcgag
    15361 cagcgcggga tcgcccgtcg cctcgtaccg gcgcagcagg aacagggcgg gcccgctcgc
    15421 gccgcgcagc aggccggcgc ggcggcgggg cggagccggg cggggctcgg cgagacggtc
    15481 gacgaggagg cgcgcggcct cggccgcccg ctcgcgcagc cccgactcac cggtggtccg
    15541 cgccagctcg tcgagcacca ggccgagccc tgccagaccc ccgcgcaggt cggacgacag
    15601 ccggtgccac ttctcggcga ggatccgctc gaccaggtcc agggcccgct gccggtggcc
    15661 cagccggtcc agggtcaggg ccacgcccgc gagcccgtcg tacaggccga gcggggtccc
    15721 gatcggcacc ggggcggtgt ggtcgagcag ccagcgctcg ccctcctcgt aacgctccgc
    15781 gccgacctcc gcgagcgtgt acaggacgcc cgccgctccg tgcgcgaggc cgagtccgcc
    15841 gccgtcggag aactgggcga cgtccccggg gaagagccgg tcgtcgcgct ccggcgtggc
    15901 cgaggccagg atcgccttga ccatcgagtc acggctgtac ggccagtccc cgggcccggc
    15961 gaggggccag tcgcccgccg gggcgcgtgt cccggccagc cgggggccgg cgtcgccgcc
    16021 cgcgcgggtg atctccgcga ccgcctcgtc gaggaacgcg ctcggcacct ccgggaactg
    16081 ctcggcgatc accgtggcca gatgggcggc cttctcccgc tccaccacga acagggacgt
    16141 gaccggcagg aacagcgcga ggcgcagaca cgccagggcg tagcggtcga cgtccgggcc
    16201 ggtgcggtcc gggggcgcga ggaagccggg gtgggcgacg gtctggcggc cgtcgtcctc
    16261 ggcgggcgcc gccgcctcga agtcgaggag ggagaccgac cgatcgtcgg gcgcgaccat
    16321 gatgttgaag acgtgcaggt cgttgaagac gatcccgcgc gagtgcaccg ccgccaccgc
    16381 ctcctccacg gcccggtgca cgtgcagcgc ccaggccgtg tacgcggtga ccgcgtccgg
    16441 ttgcgggtcc ggggccagca gggggtgccg ttcggcgacg caggagttca gcgggcggcc
    16501 ctcgacgaag tccatgacga ggaagcggtg gtcgccgagc gtgaaccagt cgcgcacctc
    16561 gggcaccaca cccagcccgg ccagccgctc cagcgcgtcc ttctcccgct ccagccgggt
    16621 caccgcgtcg gccccgtcgg cggccagccc ggcgtgcggg cgtccctcct tgaggacgac
    16681 ccggcggccg tcacgggtgt ccgtgccgac gtacaccccg ccgccgttgg agaagtgcag
    16741 ggccttgtcg atgcggtacg gcagatcgcc gacggtggtc gtgttgcgcg ccgccagctg
    16801 tggctccagg aacgcgggca gggtcaccca ctcgggcaca tggaaggtcg gcttccgctg
    16861 gtccggcacc agggtgcccg cgccgtcgcg gacggccggg acgagcgtgc cgcgctcgtc
    16921 gacgacgaag gagcgggcga aggcgccgta gcggacgtac agcggtccct cgttccagcg
    16981 caggtccgtg aggatgtacg gcccgtcgtg gcccttgagg aggtcgccca gctcgcgcag
    17041 gacgaggtgc agctgctcct cgtcgcccgg gtagaccgtg acgaacttgc cgctgctgtc
    17101 gcgggccgcg tacttggcgt tgcgcagatg cagcagatgc gggcccggca cgaacttgaa
    17161 cgggatgccg cggggcacgc agtagtccca cacgatcgcc gcgatccggt ccgcgttccc
    17221 ccgagtggcg gaggcgtgca ccttccatcc ctgggtgggt ccgggacggg gccgcccgcc
    17281 gtcgtcgacc ggtgtcagcg tcagccagtc cccgatccgg gcggcccgcc agccctcggg
    17341 aaccgcgcgc ccggcggtcg cgtaaccggg agccgccgcg ccggcgcggt cgccggccga
    17401 gagccggtcc ggtgtctcgt agaagtgtct gtcggcgagc gcgtacgcct cgtaccgctt
    17461 gtccatgccg gttcccccgg gtcgtgtgcc gtcgctccct gggccaagtg acgacgagcc
    17521 ttccagcccg ccggggcgcc cgacagtcac ggctgtcacc agaaacccgt cacggctgtc
    17581 acgcgctcac cgtgcggaac gcacgcgtaa agatgtgttc gacgttcttc gaaacgggca
    17641 gcccgcggcg ggcccccggc ccggcggaac ggtcccaggg gctgcgcgac cgtgccggaa
    17701 gcgctgtaat tgcggacgtg gtcagtgcag gcgctgcgga acgcggaacg aggacgctgc
    17761 gtgccgaact cgcgctcaag tcgctcggcg gccatctcga tccgcacgag cggctgcacg
    17821 ccatcctcga acaggtgctc gtgttcacga gtgcgagcgt cgccgccgtg tacctcccgg
    17881 acggcgaggg ccaggcgctg ctgctggccg gctccgccgg cgtcccgagg aacctgtacg
    17941 ggctccgaga cagctatccg gcggcgggga ccaccccggt cgccgaggtg tgccgttcgg
    18001 gccggcggcg ctggctcccc tccgccgacc tccagcacga cgccgacgtc cgccgggccc
    18061 acgccgagga attctcactg ggcgtgctgc cgctgcgtga acgtggctgc ctcgtcgccg
    18121 tcggcgacgg cgcggacgcc ttcgggcccg aggaccggca gtgcctcgac ctgctcgccg
    18181 aggcggtcac cagctccgca cccgcgccgc ccgccggacc cggcgcctcg ttcgacctgg
    18241 ccatggacag cgggcgggtg gaggtcgacg aggggctgct ggagctgttc ggcatgggtc
    18301 cggacgactt cgacggccgg gtggagaccc tgatcgcgct caccgtgccc gaggacctgc
    18361 ccgcgctgat gtccgtcgtg gaggcggacc acatgtcgat cggcgaccgg gagctggagt
    18421 tccgcatcct gcagccctcc ggggagcaga agtggctccg gctgcgcggc cggatcctgc
    18481 ccggcggcga ggaccggccc gcccgtctcg tcggcaccgt cgccgacgcc tccaccctgc
    18541 gcaccggccg cggcgacgtg gcccgcatcc agcgcctcgc cgcctccctg gccaccgccg
    18601 gcacggtccg tgacgtcagc caggccgtgg tgaccgccct gcgcaagccg ctgcgggccg
    18661 accggatcgc cctcgccgag ctggagggcg accgcctggt cgtcaccgtc ctcgatccgc
    18721 cgcagccgga ggtctggccc gaggtgtggc gctccgaatg gcgctccgag tggcccgacg
    18781 cgcccgtgcg caccatgccg accctcgcca ccgcgctgcg cgagggacgg gccgggatct
    18841 ggcccgccgg cgccgatctg gagcccgccc tcgccgaggt cggccccggc ggcctggccg
    18901 tcctccccct gcccgccggg ggccggatgg ccggggcctg tctgatcggc tgggacaacc
    18961 cccacgactt cggccccgag gagcgcgccc tgctcaccgc cgcctcgggc ctcgccgggc
    19021 aggccctgat gcgggcccac gccttcgacg ccgaacacga actcgtcggc atgctccagc
    19081 gcaccctcct gccgcgccgg ctgccccagc tgccgggcgc ggtcgccgtc gcccgctatc
    19141 tgcccaccac cgccggtctg gaggtcggcg gcgactggta cgacgtcatc ccgctcccgg
    19201 acaaccacgt cgccctcgtc atcggcgacg tccagggcca caacgcgggc gccgccaccc
    19261 tcatgggcca gatgcgcacc gccctgcgcg cctacgccgt cgaggggcac cccccggacg
    19321 tcgtggtctc gcacgccaac cggctcctca tggacatgga gaccgacctc ttcgccacct
    19381 gctgctacgt cgacatcgac atggaggagg ggtccgcctg gtacgtgcgc gccggacaca
    19441 tcccgccggt ggtgcgtcac ccggacggct ccaccgagat cagcgagtcg gagggcggac
    19501 cgccgctcgg cgtcgtcatg cgcgccgact tcccgatgag ccccctgcgg ctggcccccg
    19561 gctcactgct ggccctcacc acggacggcc tcgtggagtc cgccgacgtc gacgtggagg
    19621 acggcctcga ccatctcgcc gccgaactgg ccgccgccga ccccgcccac ctcggcgtgg
    19681 tcgccgacac cctgctcggc ggcgccaacc gcgacgacga cgtggccctg ctcctcgtgc
    19741 gctacgacgg catggccctg cgcccccagc gcgagaactg gagcgtctgg cgagtccccc
    19801 aggcggtcgg ccaggcccgc cgctacaccc ggcgcgtcct gcgccgctgg ggcgtggagt
    19861 ccacggccga caccgtgctc ctcgtcgtct ccgaactcgt caccaacgcc ctcgtccaca
    19921 ccgacggccg tgtacgcctc gacctcaccc ttctggccga ccgtctgcgc gtcgcggtcg
    19981 ccgactcctc cccgcgtacg ccggcgaagc ccacggtcat cggctgggag gccaccggcg
    20041 gtcgcggcat tctcctcgtc gaggccgtgt ccgcggcctg gggcaccgtc cccgtcagcg
    20101 gcgggaagca ggtgtgggcg gagatccccc tcgactgagg cgggtaccgc ccggaccggc
    20161 cggcgggtcg gtgtgcgggc cgatacgcgg ccggggccgg gtgccggtgc cggtgcgggt
    20221 gccgtcgcgt gacgcgcgct cggccggtag ctccggcgcc gccgacggcg taccgcccac
    20281 gccggatgcg accctgtctc cgtgcgcctc ctgctgacga ccgacaccca cctgccccag
    20341 cgcgccaagg cgctgcccga gcggcttctc gccgagatcg cggaggccga cgtggtcgtc
    20401 cacgccggcg actgggtcga cgaggacacc ctcgacctcc tggagacccg cgcacgccgg
    20461 ctgatcgccg tgtacggcaa caacgacggc cccgccctgc gcgcccgcct ccccgaggtc
    20521 gcccacgccg aactggccgg tctgcgcctc gccgtcgtcc acgagacggg ccccgcccag
    20581 ggccgcgagc cgcgctgcgc cgcccgcttc cccgggaccg acgtcctcgt cttcggccac
    20641 agtcacatcc cctgggacac gaccacggcc accggtctgc gcctgctcaa ccccggctcc
    20701 ccgaccgacc gccgccgcca gccccactgc acctacatga cggcgacggc gcaggacggc
    20761 ggactgacgg acgtccggct gcaccgactg ccgccccgga cccgaccgag cagctgaccg
    20821 aggcgctcgc tcccgggctc accgggacgg gtccggcggg ggatggatca ccccggtcgt
    20881 cgccgtcagg ggcaccccgc tgccgcccca cctcagcgcg acgatctccg ccgccacgga
    20941 cacggccacc tcctccggcg tacgggcgcc gaggtccagg ccgaccgggg agcgcagccg
    21001 ggacaactcg gccgcgccga gccccgcctc ccgcagccgc cgtgcccggt cgtcgtgcgt
    21061 acggcggctg cccatcgccc cgacgtacgc ggccggccgg cgcaacgcct cctgcagaag
    21121 cggcccgtcg aacttggggt catgggtgag gacgcagatc accgtgcggt cgtcggtcgc
    21181 ggtgccccgc agatagcggt ggggccagtc gacgaccacc tcgacggcgg cggggaagcg
    21241 cttcggggtg gcgaacaccg ggcgggcgtc gcacaccgtg acgcggtagc ccaggaagtc
    21301 gccgatacgg gcgacggccg ccgcgtagtc gatcgcgccg aacaccagca tgcggggctg
    21361 tggcgcgaag gagtgcagga agacggtgac cgagtcctcg cgccgctcgc cgtgcggccc
    21421 gtagtgccgc tgaccggtga caccctgggc cagctcaccc cgcgcgtcgg cggcgacggc
    21481 cacgtccagc cccgccgaac cgagggtgcc gacggtgccg tgcgcggggg acccgtcggg
    21541 cgcggcgtcc ggccacacgg cgagggtggc gccgcgcggg gccggaccgt cgaccacggt
    21601 ggccacggtc accgggtgcc cggtgcccac ggactccgcg acccgcccga acgccgggtc
    21661 ctcggccacc gtcacccgcc gcaccagcag cgtgatctcc ccaccacacg tcagccccac
    21721 cgcgaacgcg tcctcgtcgc tgtaaccgaa ggtctccagc cgcgcctccc cggacgccac
    21781 gacctcccgg gccagctcga acaccgcgcc ctccacacat cctccggaga caccgcccac
    21841 gacctcgtca ccgggcccga ccgccatggc ggcccccggc ccgcgcggcg tgctccggct
    21901 gaccgcgacc accgtggcca gtccgaaggg ggaacccgcc gcgtaccagg cgccgagcgc
    21961 cggaagaacc tcacgcacgg acccgctcct ctcgccgccg ccccgtgcct ccagcgtccg
    22021 ccgactcggc ccgcaccgcc cgccggacca acgccccggg gccgaggaaa ccgtttgcga
    22081 ccgcgcaaac cgctctgctt cactgcgaag gaacccccag cgatcaagga gagcccccga
    22141 tgcgcgcagc gtccatgtcc caccaggaag gaatgcaccc catttcgaag gacatgacgc
    22201 ttgtcacgca cgctcaacct cggcatcctc gcgcacgtcg acgcaggtaa gaccagcctg
    22261 accgaacgcc tgctgcacac cgtcggagtc atcgacgaga tcggcagcgt cgacgagggc
    22321 agcacccgca cggacaccct cgccctggaa cggcgacgcg gcatcaccat caagtccgcc
    22381 gtcgtctcgt tcgcgatcga cgatctcacc gtcaacctca tcgacacccc cggccacccc
    22441 gacttcatcg ccgaggtgga acgcgtgctc gacgtcctcg acggcgcggt cctcgtcgtc
    22501 tcggccgtcg aaggggtcca ggcgcagacc cgggtcctga tgcgcaccct gcgacgcctg
    22561 cgcatcccca cgctgatctt cgtcaacaag atcgaccgcc ggggcgcgcg ccaccaggac
    22621 ctgctggaga gcatcgcggc acgcctcacc ccggggatcg tccccatggg cgaggtcgcc
    22681 ggactcggca cacccgaggc ccacttcctt ccctacgacc ccctcccgcc ccggctcctc
    22741 gaactcctcg ccgagtacga cgacgacctg ctcgccgcct acgtcgacga cgggacggcc
    22801 gtccccgaga cccggctgcg cgcggccctc gccgcccgga ccggcgggtc cctggtccac
    22861 ccggtgttcc acggctcggc gatcacagga tcggggatcg ccgaactcgt cgacggcatc
    22921 cgggagttgc tgccctcgac cgacgcggac cacgggggcg acacggcggg cggcggagac
    22981 ggagaagcgg ccgccccacc ctccggcacc gtcttcaagg tcgagcgcgg cccggcgggc
    23041 gagaagatcg cctatgtgcg gatgttcgac ggaaccgtac gcgtccgcga ccgactggcc
    23101 ttccgtgacg gcgcccgcga aggcaaggtc accgcgatca gcgtcttcga aggcggcgcg
    23161 gacgtgcgcg cgacagccgt gtcggcgggc cggatcgcac ggctgtgggg cctcgccgac
    23221 atccggatcg gcgacaccgt cggcgtgccc cgggagcggg cggcggcggc ccacgggcac
    23281 cacttcgccc cgcccaccct cgaaacggtc gtcctccccg cccgcgccga ggacggcgcc
    23341 gccctgcacc tcgccctcac ccaactcgcc gagcaggacc cgctgatcgg tctgcgccac
    23401 gacgaactcc ggcgggagat ctcggtgtcg ctgtacgggg aggtgcagaa ggaggtggtg
    23461 caggcgacgc tcgccgacga gtacggcctc gacgtcacct tccgcgagac gacgaccatc
    23521 tgcgtcgagc gtctcgccgg ggtcggcgcg gccgtcgagt tcaacaagaa ggacggcaac
    23581 ccgttcctcg cgacggtcgg gctgcgggtg gaaccggcgc cggccggctc cggggtcgcc
    23641 ttccggcttg aggtggagct ggggtccatg ccgtacgcct tcttcaaggc cgtcgaggac
    23701 accgtccggg agacgctgga gcaggggctg cacggctggc gggtccccga ctgcacggtc
    23761 acgatgacgc actccggcta ctcgccccgg cagagccacg cccaccaggg cttcgacaag
    23821 agcatgtcga gcacgggcgc ggacttccgc gggctgaccc cgctggtgct gacggacgcc
    23881 ctgcggcggg gcggcnnnnn nnnnnnnnnn nnnnnnnnnn tgccggtgct cgccgcgctg
    23941 cgtgccgtac cccgggagac ccggacgagc ggggcggccg tacggctgga ggggctggtg
    24001 cccgctgccg gggtgcacgc gctggagcag cggctgcccg gaccgaccaa cggggagggt
    24061 gagctggaga cggcgttcga ccactacgcg cccgtcggcc gcgcggccgt cccctcccgg
    24121 ccgcgtaccg acctcaatcc cctcgaccgc aaggagtacc tgctgcacct gacccgccgg
    24181 acgggtgtct gagcggcggc gcgggagggg cgtgggggag tcccgggaca ggagcggcta
    24241 ggggtctcta tcgggtcccc gcgcgggcgc acaagggccc tccgggtcgt acagggcaaa
    24301 gaatcggtcg gggaaggtga actgtcctgc gaaaacgggt acttactcgt gcgtcagttg
    24361 ctattgacgg cccgcctgac cattgggacg gtagtgcaca tgtcgaatgt ggcggacatg
    24421 tcaagattgc gcactcgtct gctcggtgtc ctggtactcg tcaccggctt cctgaccacg
    24481 gcaggcccca cccagcccgc ctccgctctc actgatgatc tctggttcga ctcgcaggcc
    24541 gcggccaccc tcaccgtcga gggcggccgc ttcaaggacg gactcggccg cgaggtcgtc
    24601 ctgcgcggct acaacgtctc gggtgagacg aaactcaagg agaacaacgg gctgcccttc
    24661 gcctccgtcg ccgacgcgag gaagtcggcg accgcgctcc gggcactggg tggcggcaac
    24721 tccgtccgct tcctgctctc ctgggcgtac gcggagccgg tgcgcgggca ggtgagcacc
    24781 tcctacctcg cggcggccac cgcgcagatg ggcgcgttcc tggacgcggg gatcagggtc
    24841 tatcccgact tccaccagga cctgtactcc cgctggctgt tcgactccga cagctggtac
    24901 accggcgacg gcgcccccaa atgggccgtg gacctcggca actaccccga cgagtactgc
    24961 gggatctgcc cgttctgggg ccagaacatc acctccaacg cggcggtgac gaagtcgacg
    25021 tacgacttct ggcacaacac ctacggtgtc caggactcct tcctggacac cgcgcagaag
    25081 acgatggcgt acgtgaagtc caacctcacg tccgcccagt tccagggcgt cgtcggcttc
    25141 gacccgtgga acgagccgca tcccggcgtc ctcgactcgg ggcagaccag caggacgtgg
    25201 gagaaggacg tcctgtggcc gttctacgtc aagttccgct cccggatgga cgcggcgggc
    25261 tggcaggcca agccggcctt cgtcgagccg aacctcttct ggaacgccaa catcgacttc
    25321 cagaagcagg agggcggact gctcgacgcg ggcaccatcg gaccgcgcta cgtcttcaac
    25381 acccacttct acgaccagaa ggcgatctcc ggcgtcttca tgtggggcaa ggcggagaac
    25441 ggccagtacg tgaacgactt cgggaccgtg cgcgaccggg ccgccgccgg gggcaccacg
    25501 gccgtcgtca gcgagttcgg acacccgctc agcggctcgg tctccgacaa ggcgcccacg
    25561 gtctacaagg ccatgtacca ggcgctggac tcccgggtga agggcgtcga ctggtggacg
    25621 aagccggcct cctccggccc ggtcctctcc ggctcccagt ggcagtggga catctactgg
    25681 ggccgccacc acgagctgat gaacgacaac cccgacaagg tgcaggccga ggccgacggc
    25741 tggaacggtg aggacctctc cgccgtacgt gtcgacgact ccggtacggc cgtgctccgc
    25801 caggacgccc ggatgctgga ccggatctac ccgagcgcca cggcgggcag cacggtcgcc
    25861 ttcacctacg aggaccgctc gcgggacggt tccacgaccc tgacgtggaa cccggtgccc
    25921 agctcgctgc cgaacgtctc ctcgctcgtc ggctccggcc agtactccct gctggtctgg
    25981 cgctcggacg gcagtacgga gccgaccgag ctgcacctgc cggcgtcctt ccccaccgcg
    26041 tccaccacgg tggtgtccga cctcggggtg acggcggcgc cgccggcgta caccacgtcc
    26101 acaccgatcg ccgccgcgaa ggagccgggc ggcaccggca gccgccgtct gctgctgacc
    26161 gccgccgaca cgggcaagct ccactacgcc ctggtcacca acggcgcgac agccccgtcc
    26221 gccgcgcaac tgggcgcggc acggacggag ctgtcgaact ggctgaccgc caggttcagt
    26281 tagccgaggg tccggtccag tcggcgggca cctgtgccac gcgcacccgc tgggggtggt
    26341 cgccgactgc gacggacacg gtcttcttcc cggtggcgaa gtcgatcgcc gtgacctggt
    26401 cggcgccgct ctcggagacc acacaggact tgccgtcacc gctgacggtc gaccagtacg
    26461 gcttggagac ggggacgagc gggccctcct ggaaggtcgc gcggtccacg acgaccgcgt
    26521 agtcgtccat cgtgccggcg atgcacagct tcgtgccgtc cggcttcatg gtgaggccgt
    26581 ggtggcgcga gtcgttgacg aaggtggtgc ggtcgtcgct gacgcccggg gacttcggca
    26641 gggtcttggt gcgggtgatc ttgtcggtgg cgatgtcgta ctcgaagaag ccgttgaaga
    26701 acgacacctg gaagtacagc ttcgtctcgt cgggcgagaa ggcggcggga cggacggcgt
    26761 ccgagtagtc gctcagcccg atggcgtcga gccgcgcgcg catgtcgatc accttgacct
    26821 gctggaaggt gttcgcgtcg gcgaccgtga tcttgcggtc gcccttcgtc cagtccagcc
    26881 agggcgcgtc gctctgggtg ttgacgtccc cgatcgccat gttccagatg tacttgccgt
    26941 ccttggtgaa gatgttctcg tgcggcttgt cgccggtctt gaacgacccg agctgcttgc
    27001 cggtgacgat gtccagcacg tgcacggtgt tgccggtcga cgccgacacc gccacgcgct
    27061 tgccgtcggg ggagaccgcc atgtggtcgg agcggtaacc cgacaccggg aagcgccagt
    27121 tgatggcgcc ggtcctgacg ttgatggaga ccacgtcggc gaagctcggg cgggagacga
    27181 ccatggagga gccgtcgggc gtggagtaca tgtcgtcgac gtactggtcg tggccctcgc
    27241 ccacgctgtt gcggatcgtc atgtaggcga tccaccggat cgggtcggcg ttgatctccg
    27301 ccatccgggc ggccttgtcg gggatgacgt tgatccggcc gatcttggcg aagtcgccgg
    27361 aggccttgat gacgtccgcg gtgccctccc agttgttgcc cacgaacatc acctcccgca
    27421 ggtcggccgc ggcactcgcg ggtccggcgg tcgccacggc tgtggc
//
