LOCUS       NZ_KQ257861            26637 bp    DNA     linear   CON 02-JAN-2025
DEFINITION  Streptomyces stelliscabiei strain P3825 scf_652_48.1, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ257861
VERSION     NZ_KQ257861.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces stelliscabiei
  ORGANISM  Streptomyces stelliscabiei
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 309170)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Genome sequencing of plant-pathogenic Streptomyces species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 309170)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JUL-2014) Biosciences, University of Exeter, Geoffrey
            Pope Building, Stocker Road, Exeter, Devon EX4 4QD, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001189035.1-RS_2025_01_02
            Annotation Date                   :: 01/02/2025 01:49:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,536
            CDSs (total)                      :: 9,455
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 81
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 482
            CDSs (without protein)            :: 482
            Pseudo Genes (ambiguous residues) :: 0 of 482
            Pseudo Genes (frameshifted)       :: 129 of 482
            Pseudo Genes (incomplete)         :: 407 of 482
            Pseudo Genes (internal stop)      :: 20 of 482
            Pseudo Genes (multiple problems)  :: 69 of 482
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:19:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 209513
            Orig. end                         :: 236150
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ257861.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26637
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26637
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26637
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16637]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16637
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(57..72)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.03"
                     /tool="antismash"
     misc_feature    854..868
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
     gene            1903..2196
                     /locus_tag="IQ64_RS19700"
                     /old_locus_tag="IQ64_20810"
     CDS             1903..2196
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010033765.1"
                     /locus_tag="IQ64_RS19700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20810"
                     /product="putative quinol monooxygenase"
                     /protein_id="WP_046916479.1"
                     /transl_table=11
                     /translation="MNKTLLAEFTAREGTEDEVGRLILDYAKKVREEEGNLVFDVYTKA
                     SHPRAFWIFEVYRDEAAFQAHIDAPYGGPFNTALTPLIEEDASVLTFLDPVT"
     gene            complement(2440..3828)
                     /locus_tag="IQ64_RS19705"
                     /old_locus_tag="IQ64_20815"
     CDS             complement(2440..3828)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998474.1"
                     /locus_tag="IQ64_RS19705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20815"
                     /product="DUF5685 family protein"
                     /protein_id="WP_050398588.1"
                     /transl_table=11
                     /translation="MFGIIRPCRHRLGDGMRTEWMAHLCGLCLALRGEYGQFARVATNY
                     DGLIVSVLTEAQSERTGDWRRGAGPCPLRGMRSADVAQGEGARLAATVSLVLAAAKIRD
                     HVADGDGLLGRRPVTLAARRIASGWNRAGAAGGERLGFDTAVLLAAVDRQTEIERSTGL
                     GGSLLTVTEPTETATAAAFAHTAVLADRPANAEPLAEAGRLFGRLAHLLDAVEDLDADE
                     ASGAWNPIAVTGVERAEVRRLCDDAVRGIRLALSDAEFVDARLVRALLGGELERAVDRA
                     FDPRHRHDRHHQDRPQARGARLLPWLGLRTATEPTSQTGTDPACGVGALAGAAPEGARM
                     ASGRPREGECRRCGRWRRLCGSCGLCPNCCTCDDEGPDDGEFQFGNDNRDGGSGRDGSG
                     GDGWSGGSGGGNSGGYSGGSGGGHGSGGHGSGGSGGSGGGSGDGCGCGGGCCNPCKCCC
                     DCCD"
     misc_feature    4127..4142
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.35"
                     /tool="antismash"
     gene            4225..4812
                     /locus_tag="IQ64_RS19710"
                     /old_locus_tag="IQ64_20820"
     CDS             4225..4812
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ64_RS19710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IQ64_20820"
                     /product="hypothetical protein"
                     /protein_id="WP_373560600.1"
                     /transl_table=11
                     /translation="MAGTVECVCPGCRGRRFRSEVLAVRYDGYDIAEVLAATVDEALTV
                     FRGVRQIAARLQRLSDVGLGYLPLGRPATTISGGEAQRLKLAKEVGRRATGRTLYLLDE
                     PTTGLHAADTARLLDVLQRLVDAGHSVVTIEHNLDVMRASDWIIDLGPAGGAGGGRVVA
                     EGTPEQVARAAEEEDGGGSRTGGFLRELEPDV"
     misc_feature    4837..4857
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.14"
                     /tool="antismash"
     gene            4898..6397
                     /locus_tag="IQ64_RS19715"
                     /old_locus_tag="IQ64_20825"
     CDS             4898..6397
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325038.1"
                     /locus_tag="IQ64_RS19715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20825"
                     /product="hypothetical protein"
                     /protein_id="WP_046917852.1"
                     /transl_table=11
                     /translation="MKHADVLSGLAANASLPPELVDRLIELAVADTDADFTDDLAKRPD
                     LTHAQALALYARVPESGPQLACEGRLTVADVDPAADPDTALALLGEGRGDPVWGRVLVA
                     DPDFWRRQRLARCVGLPPDVVETLAAGPDVRVVGELALWTTDRALATRLAGHPNAEVRK
                     YAAWNEATPPAVLAALLDDKGLPPVQRCSVCGVEETGCEVWAYDVCGGTHETAVHDVRH
                     GALSNPATPIEAAIPFADDPSELLRRALAERSDLPPEVSRRLATDPDVHIRACIAEKPA
                     GDDALMRVLAEDEYQDVRRRLAHNPNVPLDVLARLIATTKIGPTLLPRVEAASPAEVGK
                     LAHSADSTVRMLVALRRDLPAEIRDALATDPDAKVLKSIAPHPGLSEARLRAMVDRHGV
                     QVLAAVAANPDASGALLEHLAHDCPPVHQAFREIAAHPHATPRALLACLTDGQARPIAA
                     GHPALPPQVIVELLADDDGHVAKAAAGNASLPGAVMRNLVP"
     gene            complement(6429..6665)
                     /locus_tag="IQ64_RS51095"
     CDS             complement(6429..6665)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ64_RS51095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_225966988.1"
                     /transl_table=11
                     /translation="MNQVEIYFSVVQRKVVSPNDFTDLAQVGDRLGAFEDRYNATAQPF
                     QWKFTTSDLDDLLARLDRHTTDHHEESSAEPAT"
     gene            complement(6695..7276)
                     /locus_tag="IQ64_RS51100"
     CDS             complement(6695..7276)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1229: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ64_RS51100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_225966987.1"
                     /transl_table=11
                     /translation="MAQVKGLVCRLPAESGVPLARWSCPEPAREVVAQAIACWVSASTV
                     RRWLTDDALKPWQHQSWIFITDPGFRTKAERVLGLYARTWRGVRLGEDEYVISADEKTS
                     IQARCRCHPTLAPGQARAMRVNHTYGRGGALAYLAAYDVHAAKVSGRTEPRTGIDPFMN
                     LVAQVMSTEPYASAKRVFWIVDNPPPSPTR"
     gene            complement(7188..7466)
                     /locus_tag="IQ64_RS51105"
     CDS             complement(7188..7466)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024940.5"
                     /locus_tag="IQ64_RS51105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_225966986.1"
                     /transl_table=11
                     /translation="MTGSWLSGAAWHAARGRSNARIARETGLDLDTVRCWRGRFVEHGP
                     AGLSDRERSGRPVVHRVAGGPGQGPGLPAASRERRAAGALVVPGTGP"
     gene            complement(7705..8850)
                     /locus_tag="IQ64_RS19725"
                     /old_locus_tag="IQ64_20835"
     CDS             complement(7705..8850)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014133807.1"
                     /locus_tag="IQ64_RS19725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20835"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_078907313.1"
                     /transl_table=11
                     /translation="MADHRSRGLTGLPPGSRSASIAPDPLGEPGTDPVGEPPRHGVTTG
                     FLARQLGVSPTTLRSWDRRYGLGPAVRAEGRQRRWSPEDVAMLQDMCRLTATGIPPAEA
                     ARAAMRRARGRAADVPADGAGTPSLDADASASPAKEHREHRVHREPGSYGGGSHSATAL
                     PLGDVRQECRGLARAAVRLDAAAVQEQLLTVVRTYGLVVAWEEVIAPTLRAVGRKWESS
                     GDRYVEVEHLLSWHISTTLRHLYAAAPQPQGDAPPVLLACLPDEHHTLPLEALSAALAE
                     SRVPALMLGGAVPADALDGAVRRTGPAAVALWAQSRRTAGLPLAQHTAATRWGVRGARR
                     QTPVLLCGPGWGRRTPEELLRPSGLRDAVAMLVALSTACRP"
     gene            complement(9000..10004)
                     /locus_tag="IQ64_RS19730"
                     /old_locus_tag="IQ64_20840"
     CDS             complement(9000..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007496674.1"
                     /locus_tag="IQ64_RS19730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20840"
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_046917853.1"
                     /transl_table=11
                     /translation="MSPRRPVRRGRYPLSLYRGPVAWERQRPTWREARPAVIARALKRA
                     QARPSGNWYVVGATRDLRDDRPLARTVAGREVVLWRDADGRLVAGPGVCPHLGAPLKDS
                     PVRCGTLVCHWHGLALPGTPFAGWEPLPAYDDGVLVWVRLDDVGGEAPLDAPVVPERPA
                     RAASVSAVYVGVGTCEPEDVVANRLDPWHGAWFHPYSFVDLTVADVPTGEEDAFVVDVS
                     FRLAGRLVVPVRAVFTAPEPRTVVMHITEGEGQGSVVESHATPLAPDDRGRPRTAVVEA
                     VVAASDRPGFAVARKAAPLLRPLMRAAAGRLWRDDLAYAERRWHLRSTGRFPG"
     gene            complement(10001..11053)
                     /locus_tag="IQ64_RS19735"
                     /old_locus_tag="IQ64_20845"
     CDS             complement(10001..11053)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971150.1"
                     /locus_tag="IQ64_RS19735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20845"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_078907314.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.2e-121,
                     bitscore: 397.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.2e-65,
                     bitscore: 213.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARELDAAGITEPALRDAYTRCRRLNARHGRTYFLATRLLPVER
                     RPAVHALYGFARWADDIVDSLDTNLPRHRRAADLTLLHERLERGLRDGDSTEPVVLALA
                     DTARRYAIDHQHFSDFMASMRSDLDVTDYPTYDALRAYMHGSAAVIGLQMLPVLGTVVP
                     REEAAPHAAALGLAFQLTNFLRDVGEDLDRGRVYLPADLLDAHGVDRDLLSWSRRAGHR
                     DPRITRALRAFEDLTRGVYREAAPGLAMLDPVARPCIRTAFVLYGGILDAVADDGYAVL
                     HRRAVVPRRRRAAVAADGLLRLTAARARMRAGARAGTRGTPPPSAPAPAAGHPRADVTA
                     APAPLHEEVA"
     gene            complement(11050..12594)
                     /gene="crtI"
                     /locus_tag="IQ64_RS19740"
                     /old_locus_tag="IQ64_20850"
     CDS             complement(11050..12594)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998479.1"
                     /locus_tag="IQ64_RS19740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20850"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_046917854.1"
                     /sec_met_domain="DAO (E-value: 1.8e-21, bitscore: 71.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRTVPGRTDHVVVVGAGLSGLAAALHLLGAGRRVTLVERDALPG
                     GRAGRLVRGGYRIDTGPTVLTMPELADEAFAAVGENLRDRVELVPLHPAYRALFADGSG
                     IDVHTDADAMEAEVERFAGAEEAAGYRRLRGWLEELYRAQMRRFIDTNFDSPLQLLTPD
                     LARLAALGGFGRLDARIGRHLRDERLRRVFSFQALYAGVPPERALAAYAVIAYMDTVAG
                     VYFPRGGMHALPQAMADAAAEAGADLRFGQEVTRLERSGDRVSAVVTAQEHIPCDAVVL
                     TADLPAVYGLLGRTPRRPLRIRHAPSAVVLHAGTDRTWPGLAHHTLSFGAAWRRTFDEL
                     TRTGSLMSDPSLLITRPTATDPTLAPPGHHLHYILAPCPNTDIGPDAAAWGDLAPRYRD
                     SILCELERRGFDGLADAVEEQALITPADWHAQGHAAGTPFSAAHTFAQTGPFRPRNLVR
                     GTTNAVLAGCGTTPGVGVPTVLLSGKLAAARITGGHAAPVPRRGRTARTAPEGLTS"
     gene            complement(12591..13916)
                     /locus_tag="IQ64_RS19745"
                     /old_locus_tag="IQ64_20855"
     CDS             complement(12591..13916)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020120223.1"
                     /locus_tag="IQ64_RS19745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20855"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_046917855.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-52, bitscore:
                     172.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPSDAKDHPVAASPPGSRAAPPGEPTTDAPCPGDHGPSAGTRHE
                     GRPHQPPGTSEPRGIDQDVPGAVRRVLESLLAERTERAAALDPVFAGDLAERVARFALD
                     GGKLMRPRFVWWALRACGGGAAEAEAALRIGAALELIQTCALVHDDVMDGSRLRRGRLS
                     LHADIAAQYTDGMAPADGARFGEAAAILAGDLALAWADDIVAATITAPGTDRVVRELWS
                     TMRTEMVAGQYLDIQGQATSSRSLARAIRAACLKSALYSVERPLALGAALAGADAARTR
                     ALCSAGRCVGIAFQLRDDLGDVFGGPRHTGKPTGGDIRAGKPTYLVAVAQARAEAAGDR
                     RAVTVLRQSLGDADLPESRLTEVVDVLVRTGARDLVEARIDRLVAQGLRHLESAPLEAE
                     GRLRLRELLHATAGSTPPFAARGPLDGIPVSLLPSAVEEVAR"
     misc_feature    14238..14254
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.5"
                     /tool="antismash"
     gene            14408..15034
                     /locus_tag="IQ64_RS19750"
                     /old_locus_tag="IQ64_20860"
     CDS             14408..15034
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998481.1"
                     /locus_tag="IQ64_RS19750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20860"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_046917856.1"
                     /transl_table=11
                     /translation="MTAQQAADRTHDSVALWAPVEDSVAQEELAAGFVAGDEECLTAAY
                     HRWGALVYTLARRSLGDAREAEDVRQSVFLAAWRGRAGYAPERGALGAWLVGITRRKIA
                     DALTARTRQAELVAAAGTRMAEAPVDRDTLPDAVLDRVLIGREFARIPAPQRRVLTLAF
                     YDDLTQAQIAEVTGWPLGTVKSHARRGLQRLSRSLQEGGADDHSA"
     gene            15399..16637
                     /locus_tag="IQ64_RS19755"
                     /old_locus_tag="IQ64_20865"
     CDS             15399..16637
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998482.1"
                     /locus_tag="IQ64_RS19755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20865"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_046917857.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 7.4e-105,
                     bitscore: 345.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEADVAIVGAGAAGLSLAHRLSRGAPAGPRLSVLLIDAPPGPLR
                     PPVRTWCFWEEGAGPYDAALSAVWRRLRVRTPEGRLLEEDIAPLAYKMIRSDDFEDLVS
                     RELAHSDVVRRIEAAVETVDGVTEGAEIRARTGQGVPVAVRARWVFDSRPLGSLPTART
                     TLLQHFHGWYVRAGRPVFDHGTVEFMDFRVPQPSGGLAFGYVLPTDSRRALVEYTEFSR
                     AVLAPEAYDTALRHYTEKVLGLGDFQVVSTETGVIPMTDARFDRRSGPSVFRIGAAAGA
                     TRPSTGYTFSAIQRQTRAVAGALRAGRHPLPPPAHRARSRAMDAVLLRALDSGRVDGAA
                     FFARLFSRVPAERLLRFLDGETRLHEDLALGLRTPVLPMLRSAAELSWLPRRPAPPADP
                     GMPFPGHRPGGHP"
     gene            16726..17454
                     /locus_tag="IQ64_RS19760"
                     /old_locus_tag="IQ64_20870"
     CDS             16726..17454
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998483.1"
                     /locus_tag="IQ64_RS19760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20870"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_046917858.1"
                     /transl_table=11
                     /translation="MTLLRDEDLAAAFDHASRSYDTLVAANPGYHAHLRRSARRLGLPR
                     PGTGLRVLDLGCGTGASTAALGAVLPGAEITAVDASAGMLERAARKPWRDGVSFVRAPA
                     ERLVEAGVEGPFDAVFAAYLFRNVADPDAVLSTVREVLAPHGRLAVHEYTLSGRATHRA
                     VWTGVCRGMVLPVATLLGDGDLYRHLWRSVVDFDTADTFAARVRAHGFDTVRVLPLPGW
                     QTGITHTIVARRAAASGDGR"
     gene            17451..19016
                     /locus_tag="IQ64_RS19765"
                     /old_locus_tag="IQ64_20875"
     CDS             17451..19016
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998484.1"
                     /locus_tag="IQ64_RS19765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20875"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_046917859.1"
                     /sec_met_domain="DAO (E-value: 1.2e-13, bitscore: 45.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAGRTDPMRHGRDRRARRLDPVPGAPRFTSGRPPSTAVVGGGI
                     AGLAAATALAERGTRVTLHEREASLGGRLAGRSTVLSDGTTVTMSRGFHAFFRQYYNLR
                     GLLRRTDPALARLRALPDYPLRHSDGLHDSFRHVPRTPPWSALGFVALSPSFGLRDLLR
                     MNPVAALPLLDVRVPEIHDRFDDVSARDFLDAIRFPEAAQHLAFEVFSRSFFADPRELS
                     AAEMVLMFHIYFLGSAEGLLFDVPAEPFPTALWDPLAGYLRGHGADLRTGTPVETVEPT
                     PDGGFLVVADGEERRHDAVVLALDTDGLRSLVERSPRLADAVWRERVASLRTAPPFLVS
                     RLWLDRPVAADRPGFLGTSGYGTLDNISVLDRWEGEAARWAARTGGSVVELHAYALSER
                     SPHDVEEKRLLEQLHRVYPETREATVLDQRHEWRADCPLFPVGGYHDRPTVRTGDPGLV
                     LAGDLVRTGLPVALMERAATSGFLAANALLERWGVRGQTLWTVPDQGRGPLLRRLARLE
                     RLTT"
     gene            19153..19653
                     /locus_tag="IQ64_RS19770"
                     /old_locus_tag="IQ64_20880"
     CDS             19153..19653
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998485.1"
                     /locus_tag="IQ64_RS19770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20880"
                     /product="hypothetical protein"
                     /protein_id="WP_046917860.1"
                     /transl_table=11
                     /translation="MTSPHEEAEGPDRSHRRPEGLSDATVEALGSLSKALETTERARGH
                     LFSFHQLTGTADLELDRATSLLREAGHHEWARRVETEVLGRNVIPGHWTFQIVEAYDQT
                     YYQAFKALERDAVDQLAAGRDHLYEAEMKESRRTHDHPDHTPTPDSPNTRNPTAPFDRR
                     PRP"
     misc_feature    complement(20066..20078)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.33"
                     /tool="antismash"
     gene            20179..20871
                     /locus_tag="IQ64_RS19775"
                     /old_locus_tag="IQ64_20885"
     CDS             20179..20871
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025382.5"
                     /locus_tag="IQ64_RS19775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20885"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_046917861.1"
                     /transl_table=11
                     /translation="MAYTARSRRTRRTTAVLAVLSLGIITLTACKGDAEADASGPGTAA
                     SPSASDGGKDADKPDKPSTAGQGGDDGGSGDASGGSDSTPASSEPGADDDQDGGVGMCE
                     TTDLTYKVTVASKLVNHALLAATNNSGDPCLLPANDLVITIPGLDGAAEHMGPEGKDWI
                     MKAGETAYAGILFSRADTAGGKSADKVEVALTASESPATVTIADGPVTVNDGQVTSFFG
                     TAEDALTY"
     gene            21034..21747
                     /locus_tag="IQ64_RS19780"
                     /old_locus_tag="IQ64_20890"
     CDS             21034..21747
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998487.1"
                     /locus_tag="IQ64_RS19780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20890"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_046917862.1"
                     /transl_table=11
                     /translation="MTAPLYVRIRREIEAGIRAGELPPGARLPTEKDLSTRYGVSRATA
                     QRVLNDLAEAGLAIRRRRHGTFVADVTRQINLLNFVTPATAAKGTPGRHDVVSARVVRA
                     ADAVLRLPGAAADTAVVELVRRKLDVHEKPQSVERHVVLFAAAPDLLSENLEHLVTLPY
                     LRRGGVPVDTIRLYLDPVTLDEHDAALLDSEIGTPALMRRRELRTDDGSTVEVVTTLVR
                     PGTAEFFLELPVPAM"
     misc_feature    complement(21815..21829)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
     misc_feature    complement(21816..21831)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.12"
                     /tool="antismash"
     misc_feature    21819..21834
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            21820..22986
                     /locus_tag="IQ64_RS19785"
                     /old_locus_tag="IQ64_20895"
     CDS             21820..22986
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998488.1"
                     /locus_tag="IQ64_RS19785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20895"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_046917863.1"
                     /sec_met_domain="DAO (E-value: 1.9e-43, bitscore: 143.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIIIGAGVLGVSVARHLAVAGEDVLLLDRRGAGTGTSATTFAW
                     TNSSRKPDPAYHRLNLAGMEEHARLAGRLRGAPSYFPSGALQWADAANERRLADNVARL
                     RSLGYAAEWVTADEAVRIAGDLSVPAAITALAHFPGEGYVLPDLFVRTLLADAVRHGAT
                     YLTGEVETIDDRPDGVTVTLAGGRVHTGDRVVLAAGRWTRRLAARAGIDVPMVTDTGRG
                     AQTVGLLGYARHPRLDLRCVVHSPGLNLRPAADGHTVLQALDLNADVDPADPPSADGDI
                     ADALARRFRAVLPDPAVTPRIDLRVGIRSLPADGHTIAGYASARSRVYCLVTHSGVTLA
                     PILGRLAAAEITTDLEQDLLGAFRPTRFTGAARSDTEVDQRAVGLGEQ"
     misc_feature    21821..21835
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     gene            complement(23069..>23464)
                     /locus_tag="IQ64_RS19790"
                     /pseudo=""
     CDS             complement(23069..>23464)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327492.1"
                     /locus_tag="IQ64_RS19790"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF1062 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="CTPCETPRALLERMPVRSVRPELLDRLHANDHGLTAELLQDPVVR
                     RRNRVALDWDDAWRLDTGGVDHLDREAIDVAVRFAARIPVRPVRLIAEGCGLSRAEVER
                     LVTEGKAVSTVRLSGKLSGDFTFTLKR"
     gene            23686..24633
                     /locus_tag="IQ64_RS19795"
                     /old_locus_tag="IQ64_20905"
     CDS             23686..24633
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998489.1"
                     /locus_tag="IQ64_RS19795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20905"
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_046917864.1"
                     /transl_table=11
                     /translation="MSTQDRTPDAPDAVDLPDMPAPRVREFAARSIGGGLALLLGLVGL
                     AAGVGLVVLGAVTTASGAKAALIVGGILLGLAAFLAMCGLNTVAPGEARVVQLFGRYRG
                     TIRTDGLRWVNPFTSRVKISTRVRNHETAVLKVNDAYGNPIELAAVVVWKVEDTAQASF
                     EVDDFLEFVSTQTEAAVRHIAIEYPYDAHDEEGLSLRGNAEEITEKLAVELHARVEAAG
                     VQIIESRFTHLAYAPEIASAMLQRQQAGAVVAARRQIVDGAVGMVEAALARIAEQGIVE
                     LDSERKAAMVSNLMVVLCGDRAAQPVLNTGSLYQ"
     gene            24630..24923
                     /locus_tag="IQ64_RS19800"
     CDS             24630..24923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998490.1"
                     /locus_tag="IQ64_RS19800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_046917865.1"
                     /transl_table=11
                     /translation="MTPPSPEGGPGDGQAPKRSAAQRKQVLLRLDPLVHDALARWAGDE
                     LRSTNAQIEFLLRRALSDAGRLPGAAGPLPRRGRPPKSSGDDEDAKQPGEDV"
     gene            complement(24953..25360)
                     /locus_tag="IQ64_RS19805"
                     /old_locus_tag="IQ64_20915"
     CDS             complement(24953..25360)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639900.1"
                     /locus_tag="IQ64_RS19805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20915"
                     /product="SgcJ/EcaC family oxidoreductase"
                     /protein_id="WP_078907325.1"
                     /transl_table=11
                     /translation="MNTETAELSDIKAIEEVVATVERTQRAKDAEGFLALFHPEALWTT
                     GHGKVLIGFEAIAEFTRAVLPTADWDGAVTYEAVHIQFLRPDVAAVKVRQVYHSAKGDT
                     EGAPLYVMTRQTDGTWLLHACQNTEVRFEQA"
     misc_feature    complement(25316..25330)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(25599..26144)
                     /locus_tag="IQ64_RS19810"
                     /old_locus_tag="IQ64_20920"
     CDS             complement(25599..26144)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455591.1"
                     /locus_tag="IQ64_RS19810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_20920"
                     /product="AAA family ATPase"
                     /protein_id="WP_046917867.1"
                     /transl_table=11
                     /translation="MLTVKVGTERTRLIVLRGNSASGKSSVADGLRERFGRGLALVGQD
                     NLRRTVLREHDRPGAANIGLIDLTARYALDAEYHVVVEGILYADRYGDMLARLRADHRG
                     PTHAYYLDVPFAETVARHATKPIADEIDERSLRDWYRPRDLLPDGSETVIGAHSALHET
                     VDRVLRDTGLAHLPPRDL"
ORIGIN
        1 gctcagcgag ttcggcccgg ccggcgccac gggcggcgtg tgggagtgcc ccgacctgtt
       61 ccccctcgcc gtcgacgggg acaagaacac catcaagtgg gtgctggtcg tcaacatcaa
      121 ccccggcggt atcgcgggcg gttcggcagc ccagtacttc atcggcgact tcgacggcac
      181 gaagttcacc gccgaggacg acggcgtcta caccccgccc gccgggacgg tcgtgcagga
      241 cttcgagggc accggcttcg gttcgtggac cgccacgggc accgcgttcg gcccgggacc
      301 cgcggccggg acgctcgacg ggcagcagac cgtctccggc ttcgacggca agggcctcgc
      361 caacagcttc cactccgggg acgccaccac cggcaccctc acctcgccct ccttcaccgt
      421 cgacagcccc tacctgaact tcaagatcgg tggcggccgg cacccgcacc agcccgggaa
      481 ggtcctcgcc ggcttcgagg gcggcaccta cggcgactgg acgacgaccg gcgatgcctt
      541 cggcccggca ccggccaccg gcaccctccc cggccagcag caggtctccg gcttccaggg
      601 cagcggcctg gtcaacacct tcctgaacgg cgacggcggc accggcaccc tcacctcacc
      661 cgagttcact atcgacaagc gctacgtcaa cttcctcatc ggcggcggca accaccccgc
      721 cggctccgcc gaccccaccg ccctggaact cctcgtcgac ggccaggtcg tccgcagcgc
      781 caccggcaag gacgcggagg aactggagac cgcgtcctgg gacgtccacg acctcgtcgg
      841 caagaaggca cggatcaggg tggtcgatga caacaccggc ggctggggcc acctcaacgt
      901 cgaccagatc acgctgtccg acacccaggc ccagcccggc gcccaggaga cctccgtcag
      961 tctgatcgtc gacggccagg tcgtccgcag cgcgaccggc gccgacagcg aaaccctgga
     1021 ctgggcctcc ttcgacatgc gcccctatct cggcaggaag gcgcagatcc agctcgtcga
     1081 catgaacacc ggcggctggg gccacatcct cgccgaccgg ttcaccgccg ccgacgctcc
     1141 cgccctctcc gtcctgcggc gcgcccactg ggccgactac ggcaaggact actacgcggc
     1201 cgtttcctgg gagaacaccc cgggcagcaa gcggcacatg atcggctgga tgagcaactg
     1261 ggactacgcc ggagccaccc ccacctcccc ctggcgcgga gcacagagca tcccccgcga
     1321 gatggcgctg cgcaccgtcg acggccgcgt ccggctgacc agcgagccgg tgaacagcgt
     1381 gaagtccctg cggcaggaac ctccggcgac cgcgaccgcg ggaaccgtga cgaacacctc
     1441 gaaggcactg atcggccccg ccgccgacgg caaggcgctc gacatcgaag ccaccttctc
     1501 cctcaaggac gccgaacgct tcgggctcaa ggtacgcacc ggcaccgcgg gcgaggaaac
     1561 cgtcatcggc tacgacacca cgacccagga actctacgtc gaccgcaccc gctccggcgc
     1621 cgtgaacttc aacagcacct tccccggcat ccagaccgca cctctgaagg cggcgaacgg
     1681 aaagatcaga ctgcggatcc tcgtcgactg gtcgtccgtc gaggtcttcg gcggcgacgg
     1741 cgaggccgtg atcaccgacc agatcttccc cgaccccgcc agccagggag tccaggtctt
     1801 cgccgagaac ggctcggtga agctggacaa ggccaccgtc tggcacctca cctccgccca
     1861 cgactgatcc cgacccaccc ccgacaccga aggcaccaca tcatgaacaa gaccctgctc
     1921 gccgagttca ccgcccgcga gggcacggag gacgaggtgg gccgcctgat cctggactac
     1981 gccaagaagg tgcgcgagga ggaaggcaac ctcgtcttcg acgtctacac caaggcgtcc
     2041 cacccccgcg ccttctggat cttcgaggtg taccgggacg aggccgcctt ccaggcccac
     2101 atcgacgccc cctacggcgg cccgttcaac accgccctca ctcccctgat cgaggaggac
     2161 gcgtcggtgc tgacgttcct cgacccggtg acctgagggc ccccacgcgg ccggcggcat
     2221 cggacccgcg aggggctgcc ccggggcttc ggtcccgggg cagcccccga accgacgcgc
     2281 cagccctcgg cgtcctcacc cgtggcaccg cccgacgcca ccggaacctc tgcactccgt
     2341 cgggctccca ggaccggggg gcgccccgct gacaagcagc tcgacccgct gctcagcacc
     2401 gcgctccctc gcgcacgtat ccccgacggt cacatgctct cagtcacagc agtcgcagca
     2461 gcacttgcac gggttgcagc agccgccacc gcagccgcag ccgtcacccg agcctcctcc
     2521 ggagccaccc gaaccgccgg acccgtgacc gccggaccca tgaccgccgc ccgaaccgcc
     2581 tgagtagcca cccgagttgc cgccacccga gccgccggac cagccgtcgc ccccggaacc
     2641 gtcgcggccc gagccgccgt cgcggttgtc gttgccgaac tggaattccc cgtcgtccgg
     2701 gccctcgtcg tcgcaggtac agcagttggg gcacagcccg caggatccgc acaggcggcg
     2761 ccaccggcca caccgtcggc actccccctc tcgcggccgg ccagacgcca tccgagcgcc
     2821 ctcgggggcc gcgcccgcga gcgcgccgac gccgcaggcg gggtccgtgc cggtctgcga
     2881 ggtgggttcc gtcgccgtgc gaaggcccag ccagggcagc aggcgcgcgc cccgcgcctg
     2941 ggggcggtcc tgatggtgac ggtcgtgacg gtgccggggg tcgaaggcgc ggtcgacggc
     3001 gcgctccaac tcaccgccca gaagcgcccg taccagacgc gcgtcgacga actcggcgtc
     3061 ggacagggcg agtcggatgc ctcggacggc gtcgtcgcag aggcggcgta cctcggcgcg
     3121 ctcgacgccg gtcacggcga tggggttcca cgcgccggac gcctcgtccg cgtccaggtc
     3181 ctccaccgcg tccagcagat gcgccagccg accgaagaga cggcctgctt ccgcgagcgg
     3241 ttcggcgttg gccggacggt cggcgagcac agccgtgtgc gcgaaagcgg cggcggtcgc
     3301 cgtctccgtg ggctccgtga ccgtgagcag cgagcctccg aggcccgtcg accgctcgat
     3361 ctccgtctgt cggtccaccg ccgcgagcag cacggcggtg tcgaaaccga gccgttcgcc
     3421 gccggcggcg cccgcgcggt tccagccgga ggcgatccgt cgcgccgcca gagtgaccgg
     3481 gcggcgcccc aacaggccgt ctccgtcggc cacgtggtca cgtatcttcg ccgcggccag
     3541 caccagggac accgtcgccg cgagtcgcgc gccctcgccc tgcgccacgt ccgccgaccg
     3601 catcccgcgc agcgggcacg gaccggcgcc ccgccgccag tcgccggtgc gctccgactg
     3661 cgcctcggtc agtacggaga cgatcaggcc gtcgtagttg gtggccaccc gcgcgaactg
     3721 cccgtactcg ccgcgcagcg ccaggcacag cccgcacagg tgcgccatcc actcggtccg
     3781 catgccgtcg cccaggcgat gccggcacgg tctgatgatt ccgaacaccg atgttctccc
     3841 ccgcagatac agctacccgg gcacagccag acgcacggct cacggacgcg accgcccgaa
     3901 ccgcccgaga ggcacggcca cgcgtgacat cgacgcgcgg ccgacatcct aaatggtcga
     3961 ttccgtgcgg tgtctgcagt ggcgggaacg agacgaatcc agaatcgttg cgtgacgaac
     4021 ggccgcctgg acaccgtggc tgcaccaggg ctactgcgag gcgactcggt gcctcggtgc
     4081 ctcggtgcct cggtgcctcg gtgcgatagt gagcgtccag ccgggcttgc ctaagtggtc
     4141 ggctccgtaa gcccttcggg ggttgacgtc ggaggcagtt ctgtgtctgg cgtctgctca
     4201 ggtgtcgggg gcggcgaggt ggagatggca ggcacagtcg agtgcgtctg tccgggctgc
     4261 cggggccgcc ggttccggag cgaggtcctc gcggtgcgct acgacgggta cgacatcgcg
     4321 gaggtgctgg ccgcgacggt ggacgaggcg ctgaccgtct tccggggcgt acggcagatc
     4381 gcggctcggc tgcaacggct ctcggacgtg ggcctcggct atctcccgct gggccggccc
     4441 gccaccacca tctccggcgg cgaggcccaa cgcctcaagc tggcaaagga ggtggggcgc
     4501 cgtgcgaccg gccgcaccct ctacctcctc gacgagccga ccaccggcct gcacgccgcc
     4561 gacaccgccc gcctgctcga cgtactccaa cgcctcgtgg acgcgggtca ctcggtcgtc
     4621 acgatcgagc acaacctcga cgtcatgcgc gcctcggact ggatcatcga cctcggcccg
     4681 gcgggcggcg ccgggggagg gcgggtggtg gccgagggga caccggagca ggtcgcgcgg
     4741 gcggcggagg aggaggacgg gggcggttcc cggacgggtg ggtttctgcg cgagttggag
     4801 cccgatgtct gaggccgatg tctgagtcca cactgcttcg attcggcggg acaattaatg
     4861 cctgaaggcc agggcctgtt gcggtcacaa tgctcctgtg aagcatgccg atgtcctgag
     4921 cgggcttgcc gccaacgcct cccttccgcc cgaactcgtc gaccgtctga tcgaactcgc
     4981 ggtcgccgac accgacgccg acttcaccga tgacctcgcc aaacgccccg acctcaccca
     5041 cgcgcaggcg ctcgcgctgt acgcacgcgt cccggagagc ggcccacagc tcgcgtgcga
     5101 gggccggctg accgtcgccg acgtcgatcc ggcagccgat ccggacaccg ctctcgcgct
     5161 gctcggcgag gggcgcggcg atccggtgtg gggccgggtc ctcgtggcgg acccggattt
     5221 ctggcgtcgg cagcggctgg cccggtgtgt gggcctgccg cccgatgtcg tcgagacgct
     5281 cgccgccggt ccggatgtgc gggtggtggg ggaactcgcc ctgtggacga cggatcgggc
     5341 gctggccacg aggctcgcgg ggcatccgaa cgccgaggtc cgcaagtacg cggcctggaa
     5401 cgaggcaacg ccaccagccg tactggcggc actcctcgac gacaagggac tgcctcccgt
     5461 acagcggtgc tcggtctgcg gcgtcgagga gaccggctgc gaggtgtggg cgtacgatgt
     5521 ctgcggcggc acgcacgaga ccgccgtgca cgacgtacgg cacggggccc tgagcaaccc
     5581 cgccaccccc atcgaggccg cgatcccctt cgccgacgac ccgtcggagc tcctgcgccg
     5641 ggccctcgcc gagcgctccg acctgccccc ggaggtgagc cgacggctcg ccacggaccc
     5701 ggacgtgcac atccgggcct gcatcgccga gaagccggcc ggcgacgacg ccctgatgcg
     5761 cgtactggcc gaggacgaat accaggacgt acggcgccga ctcgcgcaca accccaacgt
     5821 gcccctcgac gtcctcgctc gcctcatcgc caccacgaaa atcggcccca ccctgctacc
     5881 ccgcgtcgag gccgcgtccc cggccgaggt cgggaaactg gcccactcgg ccgactcgac
     5941 cgtgcggatg ctcgtggccc tgcgccgcga cctgcccgcc gagatacgcg acgccctcgc
     6001 caccgacccc gacgcgaagg tgctcaagag catcgccccg caccccggcc tctccgaggc
     6061 gcgactgcgg gccatggtcg accggcacgg agtccaggtc ctggcggcgg tggcggccaa
     6121 cccggacgcg tccggggcac tcctggaaca cctcgcccac gactgtccgc cggtgcacca
     6181 ggcgttccgc gaaatcgccg cccaccccca cgcgaccccg cgggccctgc tcgcctgcct
     6241 gacggacggc caggcgaggc ccattgccgc gggccatccg gccctcccgc cccaggtgat
     6301 cgtggagttg ctcgccgacg atgacggtca tgtggcgaag gcggcggcgg gcaatgcttc
     6361 gctgccgggt gcggtgatgc gaaatctggt gccttagcgg tcggctccgt aagcccttcg
     6421 ggggttgatc atgtagctgg ctcggcggag gattcttcgt ggtgatcggt ggtgtgccgg
     6481 tcgagcctgg ccagcagatc gtccaggtcg gaggtggtga acttccactg gaacggctgt
     6541 gctgtggcgt tgtagcggtc ttcgaaggcc ccaagccggt cgccgacctg ggcgaggtcg
     6601 gtgaagtcat tgggtgagac gaccttgcgc tgtacgacgg agaagtagat ctccacctgg
     6661 ttcaaccacg aagcatgcac gggggtgtgg accatcaccg cgttggggaa ggcggcgggt
     6721 tgtccacgat ccagaacacg cgcttcgcgc tggcgtaggg ctcggtgctc atgacctggg
     6781 cgaccaggtt catgaacggg tcgatgccgg tgcgtggctc ggtgcggccg gacactttcg
     6841 cggcgtggac gtcgtaggcg gcgaggtagg ccagggcgcc gccgcgtccg taggtgtggt
     6901 tgacgcgcat cgcgcgggcc tggccggggg cgagggtggg gtggcagcgg cagcgggcct
     6961 ggatggaggt cttctcgtcc gcgctgatga cgtactcgtc ctcgccgagc cggacgcctc
     7021 gccaggtgcg ggcgtacaag ccgagcaccc gctcggcctt ggtccggaag ccgggatcgg
     7081 tgatgaagat ccaggactgg tgctgccagg gcttgagcgc gtcgtcggtg agccagcggc
     7141 gcacggtgga ggcggagacc cagcaggcga tcgcctgggc gacgacctca cgggccggtt
     7201 ccgggcacga ccagcgcgcc agcggcacgc cgctctcggc tggcagccgg cagaccaggc
     7261 ccttgacctg ggccacctgc aacgcggtga acgacgggcc gccctgaccg ctcgcggtcg
     7321 gacagaccgg ccggaccgtg ctcgacgaac cggccgcgcc agcagcggac cgtgtccaga
     7381 tccagccccg tctcacgggc gatgcgcgcg ttggagcgtc cgcgtgcggc gtgccacgct
     7441 gccccagaga gccaggagcc tgtcatcgtg tcttccgcat cccagagccg accgtgggac
     7501 gttcaccggc tgcggtctgc ccagggccgg accttcctgt tcaccggggg taacgccggg
     7561 atcggctact tcgccgcgga gcagctcgcc gccaccggag ccgtcgtcgt actcggcagc
     7621 cgggacggcc gttccattct gctgcctgtc gagcgtggca agccgccgcc caggggccgc
     7681 ccccgtgtcg cgaccgcggc accgtcaggg tctgcacgcg gtggagagcg cgacgagcat
     7741 ggccaccgcg tcgcgcagcc cggacggccg gagcagttcc tcgggcgtac ggcggcccca
     7801 gcccgggccg cacagcagga cgggggtctg tctgcgtgcg ccgcggaccc cccaccgggt
     7861 cgcggcggtg tgctgggcca gcggcaggcc ggcggtgcgc cgcgactggg cccacagggc
     7921 gaccgcggcc gggccggtgc gtcggacggc tccgtcgagc gcgtcggccg ggaccgcgcc
     7981 gccgagcatc agcgccggta cgcgcgactc cgccagcgcg gcgctgagcg cctccagtgg
     8041 cagggtgtgg tgctcgtcgg gaaggcaggc cagcagtacg ggcggcgcat ccccctgcgg
     8101 ctgcggcgcg gccgcgtaca ggtgccgcag cgtggtggag atgtgccagg acagcaggtg
     8161 ctcgacctcc acgtaccggt cgccggagga ctcccacttg cggccgaccg cgcgcagggt
     8221 gggcgcgatc acctcctccc acgcgacgac gagcccgtag gtacggacca ccgtcaggag
     8281 ctgctcctga acggccgccg cgtccagccg gacagcggca cgggccagac cccggcattc
     8341 ctggcgtaca tcgcccagcg gcagggcggt ggccgagtgg gaaccgccgc cgtacgaccc
     8401 gggctcccgg tgtacccgat gctcccggtg ttccttggcc ggggatgcgg acgcgtcggc
     8461 gtcgagcgaa ggtgtgcccg ccccgtcggc gggcacatcg gcggcgcgtc cccgcgctcg
     8521 ccgcatggcg gcgcgggcgg cctccgccgg aggtatgccg gtggccgtca gccggcacat
     8581 gtcctgcagc atcgccacgt cctcgggcga ccagcggcgc tggcggccct cggcccgtac
     8641 ggcgggtccc agcccgtagc ggcggtccca ggaccgcagc gtggtcggtg acaccccgag
     8701 ctggcgtgcg aggaagcccg tcgtcacccc gtgccggggc ggctcaccga ccgggtccgt
     8761 gcccggttcg ccgagcgggt ccggtgcgat cgacgcggaa cggctgcccg gaggaaggcc
     8821 ggtgagcccc cgcgagcggt ggtccgccat gggttccgcc tccttccgcc tgccgcgggc
     8881 ccgggtggac cacgcggcat cacttccggc ggacccgggt gaacggatgc acgcgaggac
     8941 caccgcgcgt cgaaggcctg gtgcccgcgt cccggccacg gcggcacggc cgcatcgcct
     9001 cagccgggga agcgccccgt ggagcgcagg tgccagcgcc gctccgcgta ggcgaggtcg
     9061 tcgcgccaca gccggcccgc ggccgcccgc atgagtggcc gcagcagcgg agccgccttg
     9121 cgtgccacgg cgaaaccggg ccggtccgac gccgccacga ccgcctccac caccgccgtc
     9181 cggggccggc cccggtcgtc gggggccagc ggcgtcgcat ggctctccac gaccgacccc
     9241 tgtccctcgc cctcggtgat gtgcatgacg accgtgcgcg gttcgggcgc ggtgaacacc
     9301 gcccgcaccg gcacgacgag ccgccctgcg agccggaagg acacgtcgac gacgaaggcg
     9361 tcctcctccc ccgtgggtac gtcggcgacg gtcaggtcga cgaaggagta cgggtggaac
     9421 caggcgccgt gccaggggtc cagccggttg gcgaccacgt cctccggctc acaggtgccg
     9481 actcccacgt agaccgccga caccgacgcc gcacgggccg gccgctccgg caccaccggg
     9541 gcgtcgagcg gcgcctcgcc gcccacgtcg tccagccgca cccacaccag cacgccgtcg
     9601 tcgtacgcgg gcaggggctc ccagccggcg aacggggtcc cgggcagggc gagtccgtgc
     9661 cagtggcaga cgagcgtgcc gcagcgcacg gggctgtcct tcagcggcgc gcccagatgg
     9721 gggcagacgc cgggaccggc gaccagccgg ccgtccgcgt cgcgccagag gaccacctcc
     9781 cggccggcga ccgtgcgggc caggggccgg tcgtcgcgga ggtcccgagt cgcgccgacg
     9841 acgtaccagt tgcccgacgg gcgtgcctgc gcgcgcttga gggcacgggc gatcacggcc
     9901 gggcgggcct cgcgccaggt gggccgctgt cgttcccagg ccaccgggcc gcggtacagg
     9961 gacaaggggt accgtccgcg gcggacgggg cgtcgggggc tcacgcgacc tcctcgtgca
    10021 gcggggccgg tgcggcggtc acgtcggccc gcgggtgtcc ggcggcgggc gccggggcac
    10081 tcggcggtgg tgtcccccgc gtcccggcac gcgccccggc acgcatgcgg gcccgtgccg
    10141 ccgtcaggcg caggagcccg tcggcggcga cggccgcccg ccgccgccgg gggaccacgg
    10201 cccgccggtg cagcaccgcg tagccgtcgt cggccacggc gtccaggatg cctccgtaga
    10261 gcacgaacgc ggtgcggatg cagggacggg cgaccgggtc gagcatggcg aggccgggag
    10321 cggcctcgcg gtagacgccc cgggtgaggt cctcgaaggc ccgcagggca cgggtgatcc
    10381 gcgggtctcg gtggcctgcg cggcggctcc acgacagcag gtcgcggtcc acgccatggg
    10441 cgtccagcag gtcggcgggc aggtagacgc ggccccggtc gaggtcctcg cccacgtcgc
    10501 gcaggaagtt ggtcaactgg aaggcgagcc ccagggcggc ggcgtgcggg gccgcctcct
    10561 cgcgcgggac caccgtgccc aggacgggca gcatctgcag cccgatgacg gcggcggagc
    10621 cgtgcatgta ggcgcgcagg gcgtcgtagg tcggatagtc cgtgacgtcc aggtcgctgc
    10681 gcatggacgc catgaagtcg ctgaagtgct ggtggtcgat ggcgtaccgg cgggcggtgt
    10741 ccgccagggc gaggaccacg ggctcggtgc tgtcgccgtc gcgcaggccg cgttccaggc
    10801 gctcgtgcag gagggtcagg tccgccgcgc ggcggtgccg gggcaggttc gtgtccaggg
    10861 agtcgacgat gtcgtcggcc cagcgggcga agccgtagag cgcgtgcacg gcgggacggc
    10921 gttccacggg cagcagccgg gtggcgagga agtaggtcct gccgtgccgg gcgttgaggc
    10981 ggcggcagcg cgtgtaggcg tcacgcaggg ccggctcggt gatgcccgcc gcgtcgagtt
    11041 cgcgggcggt catgaggtga gtccttccgg tgcggtccgc gcggtgcgcc cgcgcctggg
    11101 gacgggggcc gcgtgccctc cggtgatccg ggcggcggcg agcttgccgg acagcaggac
    11161 ggtcggcacg ccgacgcccg gtgtggtgcc gcagcctgcg agtacggcgt tcgtggtgcc
    11221 gcgcacgagg ttgcggggcc ggaacgggcc ggtctgcgcg aacgtgtggg cggccgagaa
    11281 gggggtgccc gccgcgtggc cctgggcgtg ccagtcggcc ggggtgatca gggcctgttc
    11341 ctccacggcg tcggcgaggc cgtcgaagcc gcgccgttcc agctcgcaca ggatgctgtc
    11401 gcggtagcgg ggagccaggt cgccccatgc tgcggcatcg ggtccgatgt cggtgttcgg
    11461 gcagggggcg aggatgtagt ggaggtgatg gccgggcggg gcgagggtcg ggtcggtggc
    11521 ggtgggacgg gtgatcagca gcgacgggtc gctcatcagg ctgccggtgc gggtgagttc
    11581 gtcgaaggtg cgccgccacg ccgccccgaa ggacagcgtg tggtgcgcga gcccgggcca
    11641 ggtccggtcg gtgccggcgt gcaggacgac cgccgacggc gcgtgccgga tccgcagcgg
    11701 gcggcgcggc gtgcggccga gcaggccgta gacggcgggc aggtcggcgg tgaggacgac
    11761 ggcgtcgcag gggatgtgtt cctgtgcggt gaccacggcg ctgacgcggt cgccggagcg
    11821 ttccagccgg gtgacctcct gcccgaagcg caggtcggcg cccgcctcgg cggccgcgtc
    11881 cgccatggcc tgcgggagag cgtgcatgcc gccgcggggg aagtacacgc cggccaccgt
    11941 gtccatgtac gcgatcacgg cgtaggcggc gagcgcccgc tcgggcggca cacccgcgta
    12001 cagcgcctgg aaggagaaga cgcggcgcag gcgttcgtcg cgcaggtgac ggccgatccg
    12061 cgcgtccaac cgtccgaagc cgccgagcgc ggcgaggcgc gcgaggtcgg gggtgagcag
    12121 ttggaggggg gagtcgaagt tggtgtcgat gaagcgccgc atctgtgccc ggtacagctc
    12181 ctccagccac ccgcgcagcc gccggtagcc ggcggcctcc tcggcgcccg cgaagcgttc
    12241 gacctccgcc tccatggcgt cggcgtcggt gtgcacgtcg atgccgctgc cgtcggcgaa
    12301 cagggcccgg taggccgggt gcagggggac cagttcgacc cggtcgcgca ggttctcccc
    12361 gaccgcggcg aaggcctcgt ccgccagctc gggcatggtc agcacggtgg gtccggtgtc
    12421 gatgcggtag ccgccgcgca ccaggcgtcc ggcgcgcccg ccgggcagcg cgtcccgttc
    12481 gacgagggtg acccggcggc ccgcaccgag caggtgcagt gcggccgcca ggccggagag
    12541 tccggcgccg acgaccacga cgtgatccgt acgcccggga acggtccggt tcaacgagcc
    12601 acctcctcga cggcgctggg cagcagcgag accgggatgc cgtccagagg accgcgcgcg
    12661 gcgaagggcg gcgtgctgcc ggccgtggcg tgcagcagct cccgcaggcg cagtcggccc
    12721 tccgcctcca gcggggcgga ctccagatgg cgcaggccct gggcgaccag ccggtcgatc
    12781 ctggcctcga cgaggtcacg tgcgccggtg cgcacgagga cgtcgacgac ctcggtgaga
    12841 cggctctccg gcagatcggc gtcgcctagc gactgccgca gcacggtgac ggcgcggcgg
    12901 tcgccggccg cctcggcccg ggcctgggcg acggcgacca gataggtggg cttgcccgcc
    12961 cggatgtcgc ccccggtggg tttgccggtg tgccgagggc cgccgaagac gtcaccgagg
    13021 tcgtcccgga gctggaaggc gatgccgacg caccggcccg ccgagcacag ggcccgggtc
    13081 cgcgcggcgt ccgcgcccgc cagcgccgct ccgagggcca gcggacgctc cacggagtac
    13141 agggcgctct tcaggcaggc ggcgcggatg gcgcgggcca gcgaccggga cgaggtggcc
    13201 tggccctgga tgtccaggta ctgcccggcc accatctcgg tgcgcatggt gctccacagc
    13261 tcacggacga cgcgatcggt gcccggcgcc gtgatggtcg ccgcgacgat gtcgtccgcc
    13321 caggccaggg ccagatctcc ggcgaggatc gccgcggcct cgccgaagcg cgccccgtcc
    13381 gccggggcca tgccgtcggt gtactgcgcg gcgatgtcgg cgtgcaggga gagccgtccg
    13441 cggcgcagcc gggagccgtc catgacgtcg tcgtgaacca gcgcgcaggt ctggatcagt
    13501 tcgagcgcgg cgccgatgcg cagcgcggcc tccgcctccg cggcaccgcc cccgcacgcg
    13561 cgcagggccc accacacgaa gcgcgggcgc atgagtttgc cgccgtccag ggcgaatcgc
    13621 gcgacgcgct cggccaggtc ccccgcgaac accgggtcga gcgcggcggc acgttcggtg
    13681 cgctccgcca gcaggctctc cagtacgcgc cgcacagccc ccggcacgtc ctggtcgatg
    13741 ccgcgcggct cgctcgtgcc gggcggctga tgcgggcggc cttcgtgccg cgtaccggca
    13801 gagggaccat ggtcccccgg gcagggggcg tcggtcgtgg gctcccccgg tggcgccgcg
    13861 cgggatccgg gcggtgacgc agccacaggg tggtccttcg cgtcgctggg gcccatcacg
    13921 gttccttccg tcgcaaacac agcggtcctg cctcaacgct ttccgcggca gaggcgtccg
    13981 cggatgcgcc ggaggagtga aaaggtgcgg cccgtgcgcc gccggagggc catccgtgca
    14041 ccaggcgggg ccgtccgcgc accgcctggg gccgtccgtg cgacggtccg gcaccgtccg
    14101 cacaagggcg cggcaccgtc cgagcgatag cgcggcacca tccgtacgac ggcacggcac
    14161 cgtccgagcg acggcgggca tcgtccgtac gacggcacgg caccgtccgg cgcaaaacgc
    14221 tgcgcccgcg caaagcgctg cacaggcgat gcaagttgtc ccctcttccc tcgtcctccc
    14281 agggtggagg agttgcagga gccgagcgac gcgcgcccga cacggacggg acgggtgccc
    14341 ccacgagccc gcccgtcacc caccgggcgc aacggacaca gcccgcatcg cacaaggagc
    14401 agacgccatg actgcacagc aggcagcaga caggacccac gacagcgtcg cgctctgggc
    14461 cccggtggag gactccgtgg cgcaggagga actggccgcc gggttcgtcg caggtgacga
    14521 ggagtgtctg accgccgcct accaccggtg gggcgcgctc gtgtacaccc tggcccggcg
    14581 ctctctcggc gacgccaggg aggcggagga cgtcaggcag tcggtgttcc tcgcggcatg
    14641 gcgcggacgt gccggctacg cgccggagcg cggcgccctc ggcgcctggc tcgtcggcat
    14701 cacccgccgc aagatcgccg acgcgctgac ggcacggaca cggcaggccg aactcgtggc
    14761 ggcggccgga acacgcatgg ccgaggcgcc cgtggaccgc gacacgctgc ccgacgccgt
    14821 gctcgaccgg gtgctgatcg gccgcgagtt cgccaggatt ccggcccctc agcgccgggt
    14881 gctcaccctg gccttctacg acgacctgac acaggcccag atcgccgagg tcaccggctg
    14941 gccgctgggc accgtcaaga gccacgcccg gcgcggtctg cagcgactga gccgcagcct
    15001 gcaggaggga ggcgccgacg atcactcggc gtgatgcgga gcacggccgc ggcacggccg
    15061 gagacagcgg tgctccatcg gcgctccatc gggcactcca cgggcgctcc acgggtgcgc
    15121 tgtcgggtcg gcggtcggcg cttcatcggc gttccgtcgg tacacatcgt tgcggtatcg
    15181 gtgcggacgc agcgccgcga ctcagaaccc tgcatgcctc gtccctgggc agacggaacc
    15241 catgcgttac gcacccgctg gcccccgcaa ttcgccgtcc acccggccga caatccggcc
    15301 gagcctgcat ccgccgcggc cgccggggcg gaaagctggc gagacgccgg tggccgcaca
    15361 cgttccgccg gtgcggtcgg acagggaggg agccgtaggt gctggaagct gacgtggcca
    15421 tcgtgggcgc cggagcggcc ggactgtccc tcgcccaccg gctgtcccgt ggcgcccccg
    15481 ccggccctcg cctgtcggtc ctcctgatcg acgccccgcc cggcccgctg cgtccgccgg
    15541 tccgtacgtg gtgcttctgg gaggaggggg cgggcccgta cgacgccgcc ctcagcgccg
    15601 tctggcggcg actgcgggtg cgtacgcccg agggccggct ccttgaggag gacatcgcgc
    15661 ccctggcgta caagatgatc cgctccgacg acttcgagga tctcgtctcg cgcgaactgg
    15721 cccacagcga cgtggtccgc cgtatcgagg cggccgtgga gacggtggac ggcgtgaccg
    15781 agggcgccga gatccgggcc cgcaccggcc agggcgtccc cgtggcggta cgcgcccgct
    15841 gggtcttcga ctcccggccc ctcggaagcc tgcccaccgc ccgcaccacc ctgctgcagc
    15901 atttccacgg ctggtacgtc cgcgccgggc ggccggtgtt cgatcacggc acggtggagt
    15961 tcatggactt ccgggtcccg cagccgtccg gcgggctcgc cttcggctat gtcctgccca
    16021 ccgacagccg ccgggcgctc gtcgagtaca ccgagttctc ccgcgccgtc ctggcccccg
    16081 aggcctatga caccgcgctg cgccactaca ccgagaaggt gctggggctc ggcgacttcc
    16141 aggtcgtctc aaccgagacc ggggtgatcc ccatgaccga cgcgcgcttc gaccgccggt
    16201 cgggaccgtc ggtgttccgc atcggcgcgg ccgccggcgc cacccggccg tcgacgggct
    16261 acaccttctc cgcgatccaa cggcagacac gggccgtcgc cggcgcgctg cgcgccggcc
    16321 ggcacccgct gcctccccct gcccaccggg cgcgctcccg cgcgatggac gccgtcctgc
    16381 tcagggccct ggacagcggc cgggtcgacg gcgccgcctt cttcgcacgg ctgttctcgc
    16441 gggtgccggc ggagcggctg ctgcgcttcc tggacggtga gacccgcctc cacgaggacc
    16501 tcgccctggg cctccgcacg cccgtgctgc cgatgctccg ctccgccgcc gaactgtcct
    16561 ggctgccccg cagacccgcg ccgcccgccg accccggcat gcctttcccg ggccaccgtc
    16621 ccggcggcca cccatgaatg ccacggacac ctccgtgcgc cccgcctccg cccaccccgc
    16681 ctccgtccac tccgcctccg tccactccgc ctgaggagac accgcatgac cctgctccgc
    16741 gacgaggacc tggccgccgc gttcgaccac gcctcgcgca gctacgacac gctggtggcc
    16801 gccaaccccg gctaccacgc ccatctgcgc cgctcggcgc gccgcctcgg gctgccgcgc
    16861 cccggtaccg gcctgcgcgt cctggacctc ggctgcggca ccggtgcgtc caccgccgcg
    16921 ctcggcgccg tgctccccgg tgccgagatc accgccgtgg acgcgtcggc gggcatgctg
    16981 gagcgggcgg cccgcaaacc ctggcgcgac ggggtgagct tcgtacgcgc gcccgccgaa
    17041 cgcctggtgg aggccggtgt ggaggggccg ttcgacgcgg tgttcgcggc ctacctcttc
    17101 cggaacgtcg ccgaccccga cgccgtcctg tcgaccgtgc gcgaggtact ggcaccgcat
    17161 ggccgcctgg cggtgcacga gtacaccctc agcggccggg ccacccaccg agccgtgtgg
    17221 acaggggtgt gccgcggcat ggtcctgccc gtcgccaccc tcctcggcga cggtgacctg
    17281 taccgccacc tgtggcgcag cgtggtggac ttcgacaccg cggacacctt cgccgcccgg
    17341 gtccgcgccc atggcttcga caccgtgagg gtgctgccgc tgcccgggtg gcagaccggc
    17401 atcacgcaca cgatcgtcgc gcgccgagcg gccgcctccg gggacggccg atgagggccg
    17461 ccgggcgcac cgacccgatg cggcacggca gggaccggcg ggcccgcaga ctggaccccg
    17521 tgccgggcgc cccgcgcttc acgagcggtc gtccgccgtc caccgccgtc gtcgggggcg
    17581 gcatcgccgg actggccgcc gcgacggccc tcgccgaacg cggcacacgg gtcacgctcc
    17641 acgaacggga ggcgtccctc ggcggacgcc tggccgggcg gtccaccgtc ctgtcggacg
    17701 gtacgaccgt caccatgagc cgtggctttc acgcgttctt ccgccagtac tacaacctgc
    17761 gagggctgct gcggcgcacc gacccggctc tcgcgcgcct gcgggcactg cccgactacc
    17821 ctctgcggca ctccgacggg ctccacgaca gtttccggca cgtcccgcgc accccgccgt
    17881 ggagcgcgct cggcttcgtc gccctgagcc cctccttcgg cctgcgggac ctactgcgta
    17941 tgaacccggt cgccgcgctg ccgctgctgg acgtccgggt cccggagatc cacgaccgtt
    18001 tcgacgacgt cagcgcccgc gacttcctcg acgcgatccg gttccccgag gccgcgcagc
    18061 acctcgcgtt cgaggtgttc tcccgcagct tcttcgccga cccccgtgag ctgtcggcgg
    18121 ccgagatggt cctcatgttc cacatctact tcctcggctc ggcggaaggg ctcctgttcg
    18181 acgtacccgc cgagcccttc cccaccgccc tgtgggaccc cctcgccggc tatctgcgcg
    18241 gtcacggagc cgacctgcgc accggaaccc cggtcgagac ggtcgagccc acccccgacg
    18301 gcggcttcct cgtcgtcgcc gacggggagg agcggcggca cgacgccgtc gtcctggccc
    18361 tggacacgga cggcctccgc tcgctcgtcg aacgctcccc ccggctggcc gacgcggtgt
    18421 ggcgcgagcg ggtggcgtcc ctgcggaccg cgccgccgtt cctggtgtcc cgcctctggc
    18481 tggaccggcc ggtcgccgcc gaccgtcctg gattcctggg caccagcggc tacggcacgc
    18541 tggacaacat cagcgtgctg gaccgctggg agggcgaggc ggcgcgctgg gccgcccgca
    18601 cgggcggatc cgtggtggaa ctccacgcct acgccctgtc cgagcgctca ccccacgacg
    18661 tcgaggagaa gcgtctgctg gagcaactgc accgtgtcta ccccgagacc cgcgaggcga
    18721 ccgtcctgga ccaacggcac gagtggcggg ccgactgccc gctgttcccg gtcggcgggt
    18781 accacgaccg ccccaccgtg cgcaccggcg atcccggcct ggtgctggcc ggggatctgg
    18841 tccgcaccgg cctcccggtc gccctcatgg agcgcgcggc gacgagcggg ttcctcgccg
    18901 ccaacgcgct gctcgaacgg tggggggtga ggggccagac cctgtggacc gtgccggacc
    18961 aggggcgcgg ccccctgctg cgccgcctcg cgcgactcga acggctcacg acataggcgg
    19021 gcggcagtgg gcacccgccg ggagcggcgc cggtcggggc cccacggccg tggaccggcg
    19081 tggcagcgtt cgcggtggcc cgggtggctg ccacgctcgt cacccgtcac acacgaaagg
    19141 ggccggccga ccatgacaag cccgcacgag gaggctgagg ggcccgacag gtcgcatcgg
    19201 cgtccggaag gcctcagtga cgcgacggtc gaggcgctcg gttcgttgtc caaggcgctg
    19261 gagaccaccg aacgtgcccg aggacacctg ttctccttcc accagctgac cggcacggcg
    19321 gatctcgaac tcgaccgggc cacgtccctg ctccgcgagg ccggccacca cgagtgggcc
    19381 cgccgcgtcg aaacggaggt cctgggacgc aacgtcattc cgggccactg gacgttccag
    19441 atcgtcgagg cctacgacca gacctactac caggcgttca aggccctgga gcgagacgcg
    19501 gtggaccaac tcgccgcagg acgcgaccac ctgtacgagg cggagatgaa ggaatcccgc
    19561 cgcacccacg accacccgga ccacaccccc acacccgaca gcccgaacac ccgcaacccg
    19621 acggctccgt tcgaccgtag gccgagaccg tgaccgtgct tccattcctc catgccccct
    19681 cacggcaggg ctacggcgct gcagtcgtcg gcgcacgaat aggtgaagct gctgcccggc
    19741 gcgccgggcg ggaggttcat ggcgccgtag tggaagtggt tcagggtcgt gtcgctgcgc
    19801 tccagccgga cgtcctcggc gtactcctgc gcgccgccct ggttcaggca cgatgtccgc
    19861 ggactgcgcg gcgtggaatc cccggccgac gcgaagatca gctgcaggcc gccggccgtg
    19921 cggtcggcgg agaggactac ggcgaagaac tcgtcgctgt agcgggagat tccgatgcag
    19981 ggcgcgcggc agcgcgaacg gcgcgcggac gtatcgatgc acgcgacgtc gcgctccccg
    20041 tcaggacgcc cccgtcatgg cgcccgtcac agtgtcacaa atccgttcga agacggttct
    20101 ctctcgatat cagcgggttc cggcgccgct gccgtgcggc actatcaccc cgacattccg
    20161 tttcccgggg ggcttctcat ggcttacaca gctcgttcac gccgcacacg ccgcaccacc
    20221 gccgtactcg ccgttctctc gctcggcatc atcaccctga ccgcctgcaa gggcgacgcc
    20281 gaggcggacg cctccggccc gggcacggca gcgagcccgt ccgcctcgga cggcggcaag
    20341 gacgccgaca agcccgacaa gccctcgacg gccggccagg gcggcgatga cggcggcagc
    20401 ggggacgcgt ccggcggctc cgacagcacc ccggcatcct cggagcccgg ggcggacgac
    20461 gatcaggacg gcggcgtcgg catgtgcgag acgaccgacc tgacctacaa ggtcaccgtg
    20521 gcgtccaagc tcgtcaacca cgccctgctg gccgcgacca acaacagcgg tgacccctgc
    20581 ctgctgccgg ccaatgacct ggtgatcacg attccggggc tcgacggcgc cgccgagcac
    20641 atgggcccgg aggggaagga ctggatcatg aaggcgggcg agaccgccta cgccgggatc
    20701 ctgttctccc gcgccgacac cgcgggcggc aagagcgccg acaaggtgga ggtcgcactc
    20761 accgcttccg agagcccggc gaccgtgacg atcgccgacg gccccgtgac ggtcaacgac
    20821 ggccaggtca ccagcttctt cggcacggcc gaggacgcgc tcacctactg atcggcattc
    20881 cgcctccctg gcggagcggg gtcgcgcatc gagcacggca ccggcgcgcc ggaccccgtg
    20941 ggccagcctc caggcaattg accggtcaat tgaagaattg tacggtctaa tggcacgcca
    21001 cactgccctg cctcgcgacc tcacggaccc cctatgaccg caccgttgta cgtacgcatc
    21061 aggcgggaga tcgaagccgg gatccgcgcc ggggagctgc cccccggcgc gcggctgccg
    21121 accgagaagg acctcagcac ccggtacggc gtcagccgcg ccacggccca gcgcgtcctc
    21181 aacgacctgg cggaggcggg gctggcgatc cgccgacgcc gccacggcac gttcgtcgcc
    21241 gacgtcacgc ggcagatcaa cctgctgaac ttcgtcaccc ccgcgacggc cgccaagggc
    21301 accccgggca gacacgacgt cgtctccgcg cgggtcgtca gggccgccga cgccgtcctg
    21361 cgcctccccg gcgccgccgc ggacaccgcc gtggtggagc tggtccgccg caaactcgac
    21421 gttcacgaga agccgcagtc ggtcgagcgg catgtcgtgc tgttcgccgc cgcccccgac
    21481 ctgctgagcg agaacctcga acacctggtc accctgccgt atctgcggcg cggaggcgtt
    21541 ccggtcgaca cgatccggct ctacctcgac ccggtgaccc tcgacgagca cgacgccgca
    21601 ctgctggaca gcgagatcgg tacgcccgcg ctgatgaggc gcagggagtt gcggaccgat
    21661 gacgggagca ccgtcgaggt ggtcacgacc ctggtccgtc cgggaaccgc cgagttcttc
    21721 ctggagcttc cggtcccggc catgtgagcg gcgtgccgtc cgtgagcagc gtgccgtccg
    21781 tgagcagcgt gtcgttcccg gaaaggagat acgcagacaa tgaaggtcat catcatcggc
    21841 gccggcgtcc tgggcgtgag tgtcgcgagg catctcgccg tcgccggcga agacgttctc
    21901 ctgctcgatc ggcggggcgc gggcaccggc acgtccgcga ccaccttcgc ctggaccaac
    21961 tccagccgga agcccgatcc ggcctaccac cggctgaacc tcgcggggat ggaggaacat
    22021 gccaggctcg ccgggcgact gcgcggcgcg ccgtcctact tccccagcgg ggccctgcag
    22081 tgggcggacg ccgcgaacga gcggcgactc gccgacaacg tggcacggct gcggtccctc
    22141 ggctacgccg cggagtgggt cacggccgac gaggccgtcc ggatagcggg cgacctgagt
    22201 gttccggcgg ccatcaccgc actcgcgcac ttccccggcg agggatacgt cctgccggac
    22261 ctcttcgtcc ggaccctgct ggcggatgcc gtccggcacg gcgccacgta cctgaccggc
    22321 gaggtcgaga ccatcgacga caggccggac ggagtcaccg tcaccctggc cggaggccgg
    22381 gtccacacgg gcgaccgcgt cgtcctggcg gcaggccgct ggacgcgacg gctcgccgca
    22441 cgggccggga tcgacgttcc catggtgacg gacaccggtc gcggggcgca gaccgtcggc
    22501 ctgctcggat acgcccggca cccgcggctc gacctgcggt gtgtggtcca cagccccggg
    22561 ctcaacctcc gccccgccgc tgacgggcac accgtcctcc aggccctcga tctcaacgcc
    22621 gacgtcgatc cggcggaccc tccgtccgcc gacggtgaca tcgccgacgc tctcgcgcga
    22681 cggttccgcg cggtgctgcc cgaccccgcc gtcacaccga ggatcgatct gcgcgtcggc
    22741 atccggtcgc tgcccgcgga cggccacacc atcgccggct acgcctccgc gcggtcccgc
    22801 gtctactgtc tcgtcacgca cagcggggtg accctggcgc cgattctggg gcgcctggcc
    22861 gcggccgaga tcaccaccga cctggaacag gacctcctcg gggccttccg gcccacccgg
    22921 ttcaccggcg cggcccgctc ggacaccgag gtggaccaac gcgccgtcgg gctgggtgag
    22981 cagtagccga cggcatccgc gacggggcct gtccggcggc tcccgccggg caggcccctc
    23041 gtccggtaca ggcccgtggt ccgggggctc agcgtttgag cgtgaaggtg aaatcgccgg
    23101 agagcttgcc gctcagccgt accgtcgaga cggccttccc ctccgtgacc agcctttcga
    23161 cctcggcccg cgaaagaccg catccttcgg cgatcagtcg caccggccgg accggaatcc
    23221 gcgccgcgaa gcggacggcg acgtcgatcg cctcgcggtc caggtgatcg accccgccgg
    23281 tgtccagccg ccaggcgtcg tcccagtcca gggcgacgcg attgcggcgc cgcacgaccg
    23341 ggtcctggag caactccgct gtcaggccat ggtcgttggc atgcagccgg tccagcagtt
    23401 caggccgtac ggagcgcaca ggcatccgct ccagcagcgc tcggggggtc tcacacggtg
    23461 tacaacggca cgtcctttcg cggacgactc ggcccggaag cacggtagtt gcgcacaggg
    23521 ccgccgctcc accgctttca cttcgacgaa taaagtgata tcactatgct agatggcgag
    23581 gccggcgacc cgtcgggaac gaacccggga acagatcccc gggggcggac ccaccggaaa
    23641 cgcccctcgc ccaccactca ggccactcgc atcggggagc acaccatgag cacacaggac
    23701 cgcacgccgg acgcaccgga cgcagtcgac ctccccgaca tgccagcgcc gcgcgtgcgc
    23761 gagttcgccg cccgctccat cggcggcggg ctcgcgctgc tgctcggact ggtgggcctg
    23821 gccgccggcg tcggcctcgt ggtgctcgga gcggtgacca ccgcgtccgg cgcgaaggcg
    23881 gcgctgatcg tcggcggcat tctgctgggc ctcgccgcgt tcctggccat gtgcggcctc
    23941 aacacggtgg ccccgggcga agcccgcgtc gtccagctgt tcggacgcta ccgggggacg
    24001 atccgcaccg acggcctgcg ctgggtcaac ccgttcacgt cccgggtcaa gatctcgaca
    24061 cgggtccgca accacgagac cgcagtcctc aaggtgaacg acgcctatgg caacccgatc
    24121 gaactcgccg cggtcgtggt ctggaaggtc gaggacaccg cgcaggcgtc cttcgaggtg
    24181 gacgacttcc tggagttcgt ctcgacccag accgaggcgg ccgtacggca catcgccatc
    24241 gagtacccct acgacgcgca cgacgaggag ggtctctcgc tgcgcggcaa cgcggaggag
    24301 atcaccgaga agctcgccgt cgagctccac gcacgggtgg aggctgcggg ggtacagatc
    24361 atcgagtccc gcttcaccca cctcgcgtac gcacccgaga tcgcctcggc gatgctgcag
    24421 cggcaacagg ccggtgccgt cgtggcggcc cggcggcaga tcgtcgacgg ggcggtcggc
    24481 atggtcgagg ccgcgctcgc ccggatcgcc gaacagggca tcgtcgaact cgactcggag
    24541 cggaaggccg cgatggtgtc gaacctgatg gtggtgctgt gcggggaccg ggccgcgcag
    24601 cccgtgctca acaccgggtc gctctaccag tgacgccccc ttcccccgag ggtgggccgg
    24661 gtgacggcca ggccccgaag cggtcggccg cacagcgcaa gcaggtgctg ttgcggctcg
    24721 acccgctggt ccatgacgcg ctggcccggt gggccggaga cgaactgcgg tccaccaacg
    24781 cgcagatcga gttcctgctg cgcagggcgt tgtccgatgc cggacggctg cccggtgcgg
    24841 cggggccgct cccccgccgg gggcgtccgc cgaagtcatc gggtgacgac gaggatgcga
    24901 agcagcccgg agaagacgtg tgatccgctt cgcgagcgcc cgaccggccc gactaggcct
    24961 gctcgaagcg gacttcggtg ttctggcagg cgtgcagcag ccaggttccg tcagtctgcc
    25021 tggtcatgac gtagagcggg gcgccctccg tgtccccctt cgccgagtgg tagacctgcc
    25081 ggaccttgac ggccgccacg tcggggcgca ggaactggat gtgcaccgcc tcgtaggtga
    25141 ccgcgccgtc ccagtcggca gtcggcagca cggcgcgggt gaactcggcg atggcctcga
    25201 agccgatcag gaccttgccg tggccggtcg tccacagggc ctcggggtga aagagcgcga
    25261 ggaagccctc ggcgtccttc gcgcgctggg tacgttcgac ggtggccacg acctcttcga
    25321 tggccttgat gtctgagagt tccgcggttt cggtgttcat gcggatcact ctgcgacctc
    25381 aagcggactt gaggtcaagg ccgcagaacg cggtgcgtcc gaggccttcg gcgatgccga
    25441 cgggacatgg tcggccgacg cctggcgtgg tcggcgctgc ggtaggaccg cattcggtct
    25501 cccgggcgtt cggagggcgg cacgcagcgc gcggtagacg tcgtccgacg tcggcgtccg
    25561 ctgctcctcc cacgcggacc tgtggtccgt cccgcaggtc agaggtcccg tggcggcagg
    25621 tgggccaggc cggtgtcgcg caggacgcgg tcgacggtct cgtgcagggc gctgtgggcg
    25681 ccgatgacgg tctcgctgcc gtcgggcagc agatcacggg gccggtacca gtcgcgcagg
    25741 ctcctctcgt cgatctcgtc ggcgatcggc ttggtggcgt ggcgggcgac ggtttcggcg
    25801 aacggcacgt ccaggtagta ggcgtgggtc gggccgcggt ggtcggcgcg aagccgggcg
    25861 agcatgtcgc cgtatcggtc ggcgtacagg atgccctcga ccacgacgtg atactcggcg
    25921 tcgagcgcgt agcgggctgt caggtcgatc aggccgatgt tcgccgctcc cggccggtcg
    25981 tgctcgcgga gcacggtgcg gcggaggttg tcctgaccga ccagggccag accccggccg
    26041 aacctctcgc gcagcccgtc cgcgacggac gactttcccg aggcgctgtt gccgcgcagc
    26101 acgatcagcc gggttcgttc ggtgcccacc ttcacggtga gcactttagc gatctccgcc
    26161 cctgccgatc gcctctgccg atcggtgggc gataccccgc cgggtggctg gacctgcggc
    26221 tccgtgcgcg accagagctg ttcggggctc tagggtcgtg tcggcacggt ggggcggcag
    26281 ggacgacggt gagagtgagc gcgcgtgatc cgggttgtgg tggtggacga cgaggctctg
    26341 gtccggtcgg gtttcgggct gatcctgggc gcgtccgagg acatcgaggt cgtcgcgacc
    26401 gcgagcggcg gcgaggccgt ggcgaccgtg cggcgggagc ggcccgacgt ggtgctgctg
    26461 gacatccgga tgccggacgt cgacgggctc accgtgctgc gtgagctgcg gacgaggccg
    26521 gacgctccgg tcgtggcgat gctgacgacc ttcgacgccg acgagtacat cctcaccgcg
    26581 ctgcactcgg gcgcggccgg tttcctgctc aaggacaccg aacccgacca actggcc
//
