LOCUS       NZ_KQ257860            20936 bp    DNA     linear   CON 02-JAN-2025
DEFINITION  Streptomyces stelliscabiei strain P3825 scf_652_44.1, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ257860
VERSION     NZ_KQ257860.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces stelliscabiei
  ORGANISM  Streptomyces stelliscabiei
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 197184)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Genome sequencing of plant-pathogenic Streptomyces species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 197184)
  AUTHORS   Harrison,J., Sapp,M., Thwaites,R. and Studholme,D.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JUL-2014) Biosciences, University of Exeter, Geoffrey
            Pope Building, Stocker Road, Exeter, Devon EX4 4QD, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001189035.1-RS_2025_01_02
            Annotation Date                   :: 01/02/2025 01:49:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,536
            CDSs (total)                      :: 9,455
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 81
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 2, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 482
            CDSs (without protein)            :: 482
            Pseudo Genes (ambiguous residues) :: 0 of 482
            Pseudo Genes (frameshifted)       :: 129 of 482
            Pseudo Genes (incomplete)         :: 407 of 482
            Pseudo Genes (internal stop)      :: 20 of 482
            Pseudo Genes (multiple problems)  :: 69 of 482
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:19:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 145552
            Orig. end                         :: 166488
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ257860.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20936
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20936
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20936
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10936](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10936)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(738..751)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.23"
                     /tool="antismash"
     misc_feature    738..751
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(870..884)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     gene            898..1737
                     /locus_tag="IQ64_RS18525"
                     /old_locus_tag="IQ64_19525"
     CDS             898..1737
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474205.1"
                     /locus_tag="IQ64_RS18525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19525"
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="WP_005474205.1"
                     /transl_table=11
                     /translation="MLVNVSANGSGTPVRPGTPDRRTHDDAPDTATAFARLAAMDPGPE
                     RDHVRDELVRAWLPMAHRIASRFRNRGESLEDLRQVAAMGLVKAVDRYEPERGAFESYA
                     VPTITGEIKRHFRDRMWTLRVPRRVQDLRNKVRVARRELSQTSGGATEPSVADIAALAG
                     LTEEEVHAGMEALDSFSALSLDAEMSSGDDGYNLADTLGAPDAAYDVVVDREAVKQGLR
                     RLPERERAILYMRFFEDMTQNRIADRLGISQMHVSRLISRSCARVREEALGRTTPSS"
     gene            1796..2098
                     /locus_tag="IQ64_RS18530"
                     /old_locus_tag="IQ64_19530"
     CDS             1796..2098
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474203.1"
                     /locus_tag="IQ64_RS18530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19530"
                     /product="DUF5133 domain-containing protein"
                     /protein_id="WP_046916690.1"
                     /transl_table=11
                     /translation="MLMPHPATLRRLVEEYESLAAHEGEQSDPQATRRTQDLAYTLCVS
                     TGTRDIRQALEVARRQLAAAQATATAELCGKRVILSPEADSHGSRASGYAALHEQ"
     assembly_gap    2261..2280
                     /estimated_length=20
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <2281..2563
                     /locus_tag="IQ64_RS18535"
                     /old_locus_tag="IQ64_19540"
     CDS             <2283..2563
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020665579.1"
                     /locus_tag="IQ64_RS18535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19540"
                     /product="ATP-binding protein"
                     /protein_id="WP_233443456.1"
                     /transl_table=11
                     /translation="DLLLVVSELVTNAVRHGGGIAGFDVGLTPEGVWLSVRDNSAAVPV
                     DLHGHGALPRVHEGNGYGWPLINRLSREVRVECPAAGGKTISVLVPLT"
     gene            complement(2631..3065)
                     /locus_tag="IQ64_RS18540"
                     /old_locus_tag="IQ64_19545"
     CDS             complement(2631..3065)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005982.1"
                     /locus_tag="IQ64_RS18540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19545"
                     /product="ATP-binding protein"
                     /protein_id="WP_046916691.1"
                     /transl_table=11
                     /translation="MATESRREDKLPAEEIYDGHAAFDGELGDVTGARTAAEGFLGVLS
                     RTSPPVAVEHWDDILLVVTELAANAVQYAPGRFELTMRRTIDGVHVTLGDTSTTSPAPR
                     PFSPSKGGGGIGWYLIHTLCDEVSVVVHEHGKDVHVFLPW"
     gene            complement(3230..4957)
                     /locus_tag="IQ64_RS18545"
                     /old_locus_tag="IQ64_19550"
     CDS             complement(3230..4957)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474197.1"
                     /locus_tag="IQ64_RS18545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19550"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_046916692.1"
                     /transl_table=11
                     /translation="MSASSPDHVGRQPPGPAVRSPDGLPDLSDAGMYLVHDNGSIVSVN
                     ARAEELLGRTAAELVGHDAHDLLHRDHLGQTMTRSSCTMMRVLLSGRTGGGDREWFERG
                     DGTLLPVTWLVTPCRLDDGAAGVAVLFYESAAGNESLRSVDSTTLSQLDRLALLAETTT
                     RLTSTLDADEAIARLVRLVVPRLADWAVVDLITESDDVWRDTVATHHNGAVVRREELEG
                     PLPPVHEESFMPLSRALRGAASALAGPETYQGPPDSGITVAQQKLFQVTGLRSAAIAPI
                     RGPRAVLGALTLGLSDRPGSFTDTELSLLEDIARRAGLALENARLYQRQRHIAETMQRH
                     LLPQMPEVPGLKMAARYESASESSQVGGDWYDVFSLSDGATAVAIGDVVGHNIDAAAGM
                     AQVRNMLRAYAWALHEPPSIIVERLDQAVVNVAEASMATLIFGRVERDDEDWTLRWTNA
                     GHPPPLLITHDGRSRFLDEEHDHLLGTGLVRARSDTLTRLPPLSTLVLYTDGLIESPGQ
                     TLDRGLARLRQHAAALAHRPLHVFCDLLLERARPVDNDDDVALLVLRTPDGGGETGDL"
     gene            complement(5180..>5524)
                     /locus_tag="IQ64_RS50995"
                     /old_locus_tag="IQ64_19555"
                     /pseudo=""
     CDS             complement(5180..>5524)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138672.1"
                     /locus_tag="IQ64_RS50995"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19555"
                     /product="carboxylate--amine ligase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LGEPAAREWRAGQEPLPHSAGLLRLAAWRAARSGMSETLLDPATM
                     RPRPAAEVIHALLDHVEEALVDHGDAESARASVAELMARGNGARVQREVMERTGSLREV
                     VSACVRHTQA"
     assembly_gap    5525..5536
                     /estimated_length=12
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     CDS             complement(<5537..6218)
                     /EC_number="6.3.2.2"
                     /GO_function="GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042398 - modified amino acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=2
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009327894.1"
                     /locus_tag="IQ64_RS51000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19560"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_233443462.1"
                     /transl_table=11
                     /translation="MVDPETGEPRAQAAAVLARAAQEGTGQDVFEKELHDEQVEFATHP
                     QSSMADLGAEIIRCRKDAARHAEGLGSAVVALASSPLPVSPTITMNSRYLWMAREFGLP
                     TQVQLVCGCHVHVSVESDEEGVAVLDRMRPWLSVLTALSANSPFWQGRDSRYASYRTQV
                     WDMWPMAGPADLFGSAERYHRCVEDLISTEVVRDRGMIYFDARLSQRYPTVEIRVADVC
                     LHPDTA"
     gene            complement(<5537..>6220)
                     /locus_tag="IQ64_RS51000"
                     /old_locus_tag="IQ64_19560"
     assembly_gap    6221..6230
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     misc_feature    complement(6288..6303)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            6444..6677
                     /locus_tag="IQ64_RS18555"
                     /old_locus_tag="IQ64_19565"
     CDS             6444..6677
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474193.1"
                     /locus_tag="IQ64_RS18555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19565"
                     /product="hypothetical protein"
                     /protein_id="WP_046916693.1"
                     /transl_table=11
                     /translation="MTSPTEAGRVTGTADKDYNLIWSVEACLNNALRLETYIEDAEWEK
                     DTEVAELFRKAQADSRKGADLGKRLLHRRLSD"
     misc_feature    6706..6720
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            7002..8429
                     /gene="rox"
                     /locus_tag="IQ64_RS18560"
                     /old_locus_tag="IQ64_19570"
     CDS             7002..8429
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene="rox"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114714.1"
                     /locus_tag="IQ64_RS18560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19570"
                     /product="rifampin monooxygenase"
                     /protein_id="WP_046916694.1"
                     /transl_table=11
                     /translation="MIDVIVVGGGPTGLMLASELRLAGVGTVVLEKLTEPTGESRGQGL
                     HARSVEIMDQRGLLDRFLAVSETFRVGGLFGGIMKPWPDTLDTGHAYGVATPQPVTERL
                     LYERAVELGADIRRGSELVGLSQDPDGVSAELADGTRLRARYLVGCDGGRSAVRKLLGV
                     AFPGESATVETLLGDMAASEDPATITAVVEEVRKAELRFGLAPLEDGHYRVLVPAEGVA
                     EDRTAPPTLDEFRKQLRAFAGTDFGVHSPRWLSRFGDATRQAERYRVGRVLLAGDAAHI
                     HPPTGGQGLNLGVQDAFNLGWKLAAAVHGWAPEDLLDSYHAERHPVAARVLVNTRAQIT
                     LLASGPGPTALRQLLSELMDFEEVNRYITGMITAVDVRYDFGEGHDLLGRRMRDVRLKR
                     GRLYELMREGRGLLLDPTGTLSVEGWADRVDHVVDTAEDLDVPTVLLRPDGHVAWAGED
                     GRELLDRLPRWFGAATG"
     gene            8544..9194
                     /locus_tag="IQ64_RS18565"
                     /old_locus_tag="IQ64_19575"
     CDS             8544..9194
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005987.1"
                     /locus_tag="IQ64_RS18565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19575"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_046916695.1"
                     /transl_table=11
                     /translation="MTSPPAVRPYRPGDADALHEICIRTAHNGGDSRPFHSDPDVFPAT
                     FATPYAHLEPELTFVLDDGRGRAVGYILGTADTPAFVDAFRAQWLPLVAERFPAPLGPP
                     TTPDEVIAELLHRPERMVLPELAPYPAHLHIDILPAQQGRGHGRALLRTFLRALRARGV
                     PAVHLSMVTANTPARAFYDRMGFHGIAVPDPGPVTYLGRATTENEEPPGGTRS"
     gene            complement(9212..9865)
                     /locus_tag="IQ64_RS18570"
     CDS             complement(9212..9865)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474174.1"
                     /locus_tag="IQ64_RS18570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_078907292.1"
                     /transl_table=11
                     /translation="MTVRQVSTCLQLTSPEETTPGLREQIADCWEAVANAGGAVLATEF
                     PPLPVSAHDVAPVVDSLVHELHPARGRLLVAVVGDSLAGWLIVRREPHPLGAHCGTVNH
                     VQTHPRFRGRCIGVAPMHRVHGIARDEMGPERLSLSTRGGASLAEDWDSWWSGAAGDPE
                     LAPFLTRGDDGARPRCEGNDLTLSGHVALLREAGFEHVGAVWQVGPSHVLAAVR"
     gene            complement(10001..10936)
                     /locus_tag="IQ64_RS18575"
                     /old_locus_tag="IQ64_19585"
     CDS             complement(10001..10936)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474173.1"
                     /locus_tag="IQ64_RS18575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19585"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_046916696.1"
                     /sec_met_domain="phytoene_synt (E-value: 1e-27, bitscore:
                     90.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-14,
                     bitscore: 47.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTWKQSLDAAGVREPESRRDYDRQRDLVARARRTSYLAARLLLP
                     RALLPHVVAATAMMHHSDDLLDTGPKQSRVSAWASWEREVREALETGVSTDPLIRALLN
                     SAAARPELRVAVERYLDTATVDLEFTGFTTEADYQAYVDAYSLPAFMLVASLLGPEGDD
                     GRFRAACRTLMEGSQRLDFVNDLAEDLPEGRLGIPAETLKRFSVTAEDLAEGRESSGVR
                     ELVEDQIEAARVRLRAARALPVLTQGPGGVLLRTVIDIELLTADAAFARGARLLRGSAS
                     PPVPATARTLLGARREARGMRGPRGTLGAR"
     gene            11104..12102
                     /locus_tag="IQ64_RS18580"
                     /old_locus_tag="IQ64_19590"
     CDS             11104..12102
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467906.1"
                     /locus_tag="IQ64_RS18580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19590"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_050398564.1"
                     /transl_table=11
                     /translation="MIGTVFRSEDVPAEDRFDFWRELLGTTRASEAISPHSADFWGELR
                     LMELGPVTVWPASFLPSRYRRDQRMVRRSDPELYHLTLLLDGGLALDHADRCDTFGPRD
                     LHLADSSRPYDIRSADGGGTGVIKGVGVDFPKALFPLPPHQVRELLGRGLSGREGLGAL
                     LADFLIGLERQADSLQPSDAARLGTVVLDLLSAWFAHALEAEAALSPETRLHALTRRIQ
                     AFIRQNLHDPELAPPVIAAAHHISLSYLHRVFQQQTDGETVAAWIRARRLEGAGRDLAD
                     PSLRTTPIHVIAARWGMPRASDFTRAFRTAHGIAPSEFRLRALSDVDERGH"
     gene            12112..12570
                     /locus_tag="IQ64_RS18585"
                     /old_locus_tag="IQ64_19595"
     CDS             12112..12570
                     /NRPS_PKS="Domain: Polyketide_cyc2 (1-150). E-value:
                     6.8e-08. Score: 25.0. Matches aSDomain:
                     nrpspksdomains_IQ64_RS18585_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557388.1"
                     /locus_tag="IQ64_RS18585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19595"
                     /product="SRPBCC family protein"
                     /protein_id="WP_046920149.1"
                     /transl_table=11
                     /translation="MYATRVSRHVNAARADVYRALVDPDAIARWRVPDGMSGEVHEFDA
                     REGGRFRVSLTYDTPAGTGKSASHTDTYHGHFARLVPDEEVVEVLRFESDDPALRGTMT
                     MTTRLTDADGGTEVLVVHEGIPDAVPAADNETGTRMALENLARLVEGS"
     aSDomain        12115..12561
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IQ64_RS18585_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="6.80E-08"
                     /label="IQ64_RS18585_Polyketide_cyc2.1"
                     /locus_tag="IQ64_RS18585"
                     /protein_end="150"
                     /protein_start="1"
                     /score="25.0"
                     /tool="antismash"
                     /translation="YATRVSRHVNAARADVYRALVDPDAIARWRVPDGMSGEVHEFDAR
                     EGGRFRVSLTYDTPAGTGKSASHTDTYHGHFARLVPDEEVVEVLRFESDDPALRGTMTM
                     TTRLTDADGGTEVLVVHEGIPDAVPAADNETGTRMALENLARLVE"
     gene            12962..13351
                     /locus_tag="IQ64_RS51005"
     CDS             12962..13351
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025587.5"
                     /locus_tag="IQ64_RS51005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-oxoglutarate and iron-dependent oxygenase
                     domain-containing protein"
                     /protein_id="WP_225966595.1"
                     /transl_table=11
                     /translation="MTELQTFVLPPVVDGSDVDKALGQALIAAWQADGIFQIQATPEQE
                     AATERALDASRGFFGRPFEEKSGHVSDLTYSGYVASGEEETAGEKDGSEIYTVCPDIPE
                     DDARAVDKWPCHGPAPWPSEQYAAP"
     gene            13348..14004
                     /locus_tag="IQ64_RS51010"
     CDS             13348..14004
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015150.5"
                     /locus_tag="IQ64_RS51010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2OG-Fe(II) oxygenase family protein"
                     /protein_id="WP_225966594.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 2.7e-22, bitscore:
                     72.8, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYMGAVGDIGERLLRLVALGLGLDDMDHFTKLTEDGWHHMRVL
                     RFPRADATSERGIGSHTDYGLLVIAVQDDVGGLYIRPPVPGETRGRNWLADESMAGRYE
                     NEEPWTFVTPVPSVFTVFPGDIMQFITGGTLLSTPHKVRLADRERYTIAYFHEPSFQAV
                     ARPLEGSAPDEFIHYGTHFTNMFMRCYPDRAATARIENEDRLAVLERLRKEALNS"
     gene            complement(14077..14946)
                     /locus_tag="IQ64_RS18595"
                     /old_locus_tag="IQ64_19605"
     CDS             complement(14077..14946)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006005.1"
                     /locus_tag="IQ64_RS18595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19605"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_179860213.1"
                     /transl_table=11
                     /translation="MTLTSPPVPDDDRQVKRGVQALRDTAGVDLAFGGVVVRGRHAQLT
                     EFTGNDTNALSGLTLGFGMGLGGKVVALHRPIAVNDYANCKQISHHYDLMVAAEGIHAV
                     VAAPVVVNRTVRAVMYGAVRRSVALGDRTVDSVMRAARDLEQSLAVRDEVMRRLDGLRA
                     SSERAEGSERPTSPRWETIREAYAELRILAQRLPDDEARDRVVGVCDKLAGAGTGAPAS
                     HPPSALSARELDVLSCVALGRTNADVADELGLRAETVKSYLRSAMRRLGCHTRMETVMT
                     ARRLGLLP"
     misc_feature    complement(14881..14883)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15181..15194
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            15403..16269
                     /locus_tag="IQ64_RS18600"
                     /old_locus_tag="IQ64_19610"
     CDS             15403..16269
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474167.1"
                     /locus_tag="IQ64_RS18600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19610"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_046920147.1"
                     /transl_table=11
                     /translation="MLPAEDSEEAAAARAAVLALRRESGMSVAGVAWVVGPGQLRIGET
                     SGVRSRDRRGLSVPAGAGLIGKVLTTGRPAAVSDYRSARRISHEYDSFVSAEGVRAMAA
                     APVIVGTTVRAVLFVGSRDAVRLGDRVLTAVTRAARDLEQFLACQEQVHRLLSEARAGR
                     VGTAPRDDTAWERVHEAHADLLELTAALDDGHLKERFHEVCRLLERGCCSEGPGESVPE
                     RPSRLSPRELDVLTAVAAGCTNLDISARLDIGLETVKGHLRSVMRKLGTTTRFEAVTAA
                     RRAGLLP"
     gene            complement(16347..17888)
                     /locus_tag="IQ64_RS18605"
     CDS             complement(16347..17888)
                     /EC_number="2.7.11.-"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="IQ64_RS18605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_050398565.1"
                     /sec_met_domain="Pkinase (E-value: 1.7e-48, bitscore:
                     158.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPGHGDDQTATRAQHGAERLIAGRYLLHEVLGRGGMGTVWRAHD
                     QLLDRPVAAKELHILTHGDEEHRVRMRRAVREARAVARVPHPHVVGIHDLVEAEDRLWI
                     VMELVAGPSLAGRIAQGGPLTPRHAAALGLQMLAALEAVHAAGALHRDVKPANVLLRRD
                     DDAVLTDFGIAALDDGEFLTGTGQLVGSLEYMAPERVTGTESGPASDLWSLGATLATVC
                     GGQSPFRRPGGPATLHAVAYEEPVLPERLGPLRPVVEALLRKSPGERPSAAGVRAALGR
                     VAAGETDAGPLPSATVRVPRPFASSADADTVTGGQGRPVRAGRTVPTAGHASSPAPSPR
                     PAGRKGLWWALAGTAVLAAGGAGGLFLSGLLPLEKEPTTTTVSHVVQSATGWQPVTGVA
                     VRRGDRVTVRFVSGEWTADHRNMPMTGPAGYDAATNARLDGAKDCKVKAAAPFGTLLAV
                     LTGDRKFPVHTVARKLTFVATGDGTLHLGMNDAAGSCSEDNRGTLIVRVAVTHRS"
     misc_feature    17896..17911
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            complement(18124..19161)
                     /locus_tag="IQ64_RS18610"
                     /old_locus_tag="IQ64_19620"
     CDS             complement(18124..19161)
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0071704 - obsolete organic substance
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474166.1"
                     /locus_tag="IQ64_RS18610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19620"
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="WP_050398566.1"
                     /transl_table=11
                     /translation="MPLKNHRGTACLAASLAGVTAFGGLVASPASAAPAAPHHASPPPV
                     SEFRGVNWADPRDNYADDAVVPSGLSTTDGYATTYAKSKAIIGGFSKLGANTVRLPVNP
                     TSVNGPFWKSYRGAIDAATAKGFKVVLGYWEADNAKDGKIDDQATWDRMWRRITSAYGH
                     NGQVYFEPMNEPFGYTSQEWRDVAARWLDKHRSIPRDRVLIGGYKYSEDVKPVCADKRL
                     DGTRIALHNYGFWHTDWTSVDQWKADFKERIGTCASRTILDEFGASMTTGLDYNGPVNG
                     SNEVAYIQAATDVIRELRLGSVYWPGLRNGDTYSLTTLQGTGTRLSLKVNNQSGLDRLH
                     WAWKK"
     gene            complement(19297..20559)
                     /locus_tag="IQ64_RS18615"
                     /old_locus_tag="IQ64_19625"
     CDS             complement(19297..20559)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474164.1"
                     /locus_tag="IQ64_RS18615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ64_19625"
                     /product="DUF2993 domain-containing protein"
                     /protein_id="WP_046913686.1"
                     /transl_table=11
                     /translation="MRSPHRTDPHEPALDRSTAPRNPYDELGTLDDGPLEATSLEDFFD
                     EDTTRAPTGQGDEREPEWTPPVHRRGGRRRRGRGRFTGLPLAVKAVVGMVVLASFVTLA
                     DRWAVLYAEHRAADTLEDRLDLAAAPEVEIGGFPFLTQLAGKRLDSVRVTVPDVAADRV
                     SLAKVSATAHDVRLDADGLTSVRGARVPRLDGDVLLSFADLNRELGASQVTFTGDGRDR
                     VRARGTLPVAGRDLRLRAEATIQREGERGIATRIGGMRLDIGDLATYRPGTRASDGLHL
                     TPKAAAGLARETRRAKALLSVPAIVKRLGVSDATARAALSDDGELAEVTGSPRFARQAR
                     SLNLIDLALDNPALLRDLGLDPNLLNALSRLTRPVLADQLSLSFQLPEPERGSMRLRDV
                     RVEEDGIRVRLTGSELAVGGP"
     misc_feature    20612..20627
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.73"
                     /tool="antismash"
ORIGIN
        1 gacgccttgc gcgcctcgat gacctcctcc tccgacagcg acatcagctc ggacagctca
       61 cgtgtcgtcg gcatccggcc cagccgggac tgcagctcgt ccgtcgcgcg ggccagctcc
      121 acccgcgcct cctgcagccg ccgcggcaca tgcaccgccc agctcgtgtc ccggaagaac
      181 cgcttgatct cgccgacgat gtacggcacg gcgaacgtgg tgaactccac ctcccgggac
      241 agctcgaacc ggtcgatggc cttgatcagc ccgatcgtgc ccacctggac gatgtcctcc
      301 agggagtcct cgcgtccgcg gaagcgcgag gccgcgtacc gcacgaggga caggttcatc
      361 tcgatgagcg tgttgcgcac gtactgatac gcgtgcgtgc cctcctccag cacggccagc
      421 cggtcgaaga actgccgcga catcgcccgt gcgtccttgg gcctgacctg tgacgggtcc
      481 tcgatcagcg ggaggtccac ttcctccgac atgaccctcc cccgtgccgt ggccgtagta
      541 agtgccgtca cggctgccat gctgtccacc cctctcgccc agagcctcgt tgccaaccca
      601 cgcttgcccc caaagccgcg actcagtccc cctcggaccc gaaaggggcc gtgtcgctcc
      661 ccactctggc caaaagtcgc cgtcggcccc ggagacgggc ggatccggag ccgagccgct
      721 gcgtcaccat gaatacgcga accgttgttt gtccacggaa tcgcggggca atcggagttc
      781 cacgcctccg gatcggaggt cggtcggcgg gagcggtcgt ccgcgcacgg acttggtcgc
      841 ccattcaccg ttccccgccg cgaagtccct gaaagcgtcg ttcaggagcg atttcccatg
      901 ctggtcaatg tgtccgcaaa cggttcaggc acccccgtac gtcccggtac gcccgacagg
      961 aggacgcacg acgacgcccc cgacaccgcc accgccttcg cccggctcgc cgccatggac
     1021 ccggggccgg aacgcgacca cgtccgggac gaactcgtcc gcgcctggct gcccatggcc
     1081 caccgcatcg cgagccgctt ccgcaaccgc ggcgagtcgc tggaggacct gcgccaggtc
     1141 gccgcgatgg gcctggtcaa ggcggtggac cgctacgagc ccgagcgggg ggcgttcgag
     1201 agctacgccg tgcccaccat caccggcgag atcaagaggc acttccgcga ccggatgtgg
     1261 acgctgcgcg tcccccggcg ggtccaggac ctccgcaaca aggtacgggt ggcgcgccgc
     1321 gaactcagcc agacctccgg cggcgccacc gagccctcgg tcgccgacat cgccgccctg
     1381 gcgggactca cggaggagga ggtccacgcg gggatggagg cgctcgacag cttcagcgcc
     1441 ctgtcgctgg acgccgagat gtcctccggc gacgacggct acaacctcgc cgacaccctc
     1501 ggcgcaccgg acgccgcgta cgacgtggtg gtggaccgcg aggcggtcaa gcagggcctg
     1561 cgccgactgc ccgagcgcga gcgcgccatc ctctacatgc gcttcttcga ggacatgacg
     1621 cagaaccgta tcgccgatcg cctgggcatc tcgcagatgc atgtctcccg cctcatcagc
     1681 cgcagctgcg cccgcgtccg tgaggaggcc ctcggccgca ccacgccgtc ttcctgaccc
     1741 tcgccgcccc acccgtgtcc ccctgccgtc atcggatcac ccaggagcga aacagatgct
     1801 gatgccccac cccgcgaccc tgcgcaggct cgtcgaggag tacgagtcac tggcggcaca
     1861 cgagggtgag cagagcgatc cccaggccac gcggcgcacg caggacctgg cctacacgct
     1921 gtgcgtgtcc acgggcaccc gcgacatacg ccaggccctc gaagtggcac gcaggcagct
     1981 cgccgcggcc caggccaccg cgacggcgga gttgtgcggg aagcgggtga tcctctcccc
     2041 ggaagccgac agccatggtt cgcgcgcgag cgggtacgcg gcgctgcatg aacagtgacc
     2101 agccgggccc ttgcgagtcg tcgaccccgc acgtcccgtg atgccggggg agcgccaccg
     2161 cctcaccgac cacgacgtcg gccccgcgga ggaaccgccc ggccggccgg tgggaccccc
     2221 ggtcgcgatc accaccgccg gggcggcccc ccgccccgtg nnnnnnnnnn nnnnnnnnnn
     2281 cgatctcctg ctcgtcgtgt cggaactggt cacgaacgcg gtccggcacg gcggcgggat
     2341 cgccggtttc gacgtcggcc tcacccctga gggggtgtgg ctgagcgtgc gggacaacag
     2401 cgccgccgtg cccgtggacc tccacgggca cggcgcgctg ccgcgtgtcc acgagggcaa
     2461 cggctacgga tggccgctga tcaaccggct gtcccgcgag gtccgcgtcg agtgccccgc
     2521 ggccggcggc aagacgatca gtgtgctggt gccgctgacc tgacgcggca cctcgcccat
     2581 gttccctgtc ctctccctct ggcctcttcg cgtgtccttc tcgcgccgcc tcaccagggc
     2641 aggaagacgt gcacgtcctt gccgtgctcg tgcaccacca cgctcacctc gtcgcacagt
     2701 gtgtggatca gataccagcc gataccgccg ccgcccttgc tgggactgaa ggggcgcggc
     2761 gccggcgacg tcgtgctcgt gtccccgagc gtcacatgga ccccgtcgat ggtgcggcgc
     2821 atcgtcagct cgaagcgccc aggtgcgtac tgcaccgcgt tggcggccag ctccgtgacc
     2881 accagcagga tgtcgtccca gtgctcgacc gccaccggcg gcgaggtgcg ggagagaacg
     2941 cccaggaacc cttcggcggc cgtacgggcg cccgtcacgt cgcccaactc tccgtcgaag
     3001 gcggcgtgtc cgtcgtagat ctcctcggca ggcagtttgt cttccctacg tgactctgtt
     3061 gccaacttgt cttcccccgc tcggcttctt gaggcggacg tgatgtctcg tccccctccg
     3121 acgctcgtgt ttcccgtggg tggagtggct acgcgtgcga aagcgtaggg atgtgtgggg
     3181 ccttggggaa gagagtggct ctccggtgcc catggtgagc gtcggcgcac tagaggtcac
     3241 cggtctcacc gcccccgtcc ggtgtccgca ggacaagcag ggccacgtcg tcgtcgttgt
     3301 cgacgggacg ggcgcgctcc agcagcaggt cgcagaagac gtgcaggggc cggtgggcga
     3361 gggccgcggc atgctggcgc agccgggcca ggccccggtc gagcgtctgc cccggcgact
     3421 cgatcagacc gtccgtgtac agcacgagcg tggacagcgg cggcagccgc gtgagggtgt
     3481 cggagcgcgc ccggaccagg cccgtgccga gcaggtggtc gtgttcctcg tccaggaacc
     3541 gggaccggcc gtcgtgcgtg atcagcagcg gcggcggatg cccggcgttg gtccaccgca
     3601 gggtccagtc ctcgtcgtcg cgctccacgc ggccgaagat cagggtggcc atggacgcct
     3661 cggccacgtt caccacggcc tggtccagcc gttccacgat gatgctcggc ggctcgtgca
     3721 gggcccaggc gtaggcccgg agcatgttgc ggacctgcgc catgcccgcg gccgcgtcga
     3781 tgttgtgccc gacgacgtcg ccgatggcca ccgccgtggc accgtccgac aacgagaaca
     3841 cgtcgtacca gtcgccgccg acctgggagg actccgacgc cgactcgtag cgggcggcca
     3901 tcttcaggcc cggaacctcc ggcatctggg gcagcagatg gcgctgcatg gtctccgcga
     3961 tgtgccgctg gcgctggtac aggcgcgcgt tctccagtgc cagcccggcc cggcgtgcga
     4021 tgtcctccag cagggacagc tcggtgtcgg tgaaggaacc cggccggtcg ctgaggccca
     4081 gggtgagggc gccgagcacc gcgcgcggcc cgcggatggg cgcgatcgcc gccgagcgca
     4141 gacccgtgac ctggaacagc ttctgctgtg cgaccgtgat cccggaatcg ggcggcccct
     4201 ggtaggtctc cggcccggcg agggccgacg ccgccccgcg cagggcccgg gacagcggca
     4261 tgaacgactc ctcgtgcacc ggcggcagcg ggccctccag ctcctcgcgc cgcaccacgg
     4321 caccgttgtg gtgggtcgcc accgtgtccc gccagacgtc gtcgctctcg gtgatcaggt
     4381 ccacgacggc ccagtccgcc agccgcggta cgaccagccg gaccaggcgc gcgatcgcct
     4441 cgtcggcgtc cagcgtcgag gtcagccggg tcgtcgtctc ggcgagcagc gccagccggt
     4501 ccagctggga cagcgtcgtc gaatcgacgg accggagcga ctcgttcccc gcggcggact
     4561 cgtagaagag gacggcgacg ccggccgccc cgtcgtcgag ccggcacggg gtcaccagcc
     4621 aggtcaccgg cagcagtgtg ccgtcgccgc gctcgaacca ctcgcggtcc ccgccgcccg
     4681 tacggccgct gaggagcacc cgcatcatcg tgcacgacga ccgggtcatc gtctgtccga
     4741 ggtggtcgcg gtgcagcagg tcgtgggcgt catggccgac gagttcggcg gccgtgcggc
     4801 cgagaagttc ctccgcgcgg gcgttcaccg agacgatgga gccgttgtcg tgcaccagat
     4861 acatgcccgc gtccgagaga tcgggcagcc cgtccgggga ccgcacagcc gggccgggcg
     4921 gctgccggcc gacgtgatcc ggactcgacg cgctcatgtt cgggctcctc ctgctccggt
     4981 cgtggacggg actgtagtac gcctcggcgg gcgtgtccgt cctgcgtgcc tcacgcagta
     5041 ccccgctccc cggcccccta cgcgcaaaag gtcccagaca gcaggtcaaa ggccccgccg
     5101 acggctgtcg cggcggtgcg cggtgtgtgc ggtgtgcggc aggccgtggg cgacggcccc
     5161 gtcacccagg cctgccacct caggcttggg tgtgccgtac gcacgccgag acgacctcgc
     5221 gcaggctccc cgtgcgctcc atcacctcac gctgcacccg ggccccgttg ccgcgcgcca
     5281 tcaactccgc gacggacgcg cgggccgact cggcgtcacc gtggtcgacg agggcctcct
     5341 cgacatggtc gaggagcgcg tggatcacct cggcggcggg ccggggccgc atcgtcgcgg
     5401 ggtccaggag ggtctccgac ataccggagc gggcggcccg ccaggcggcc agccgcagca
     5461 gcccggcact gtgcgggaga ggttcctgac cggcccgcca ctcgcgggcc gcgggctccc
     5521 cgagnnnnnn nnnnnngcgg tgtcggggtg cagacagacg tccgcgaccc ggatctcgac
     5581 ggtcgggtac cgctgggaga gccgagcgtc gaagtagatc attccccggt cgcgtacgac
     5641 ctccgtggag atcagatcct cgacgcaccg gtggtatcgc tccgccgaac cgaagaggtc
     5701 ggcgggcccg gccatcggcc acatgtccca cacctgggtg cggtagctgg cgtaccggct
     5761 gtcgcggccc tgccagaacg gggagttcgc gctcagggcc gtcaggaccg acaaccacgg
     5821 ccgcatacgg tccaggacgg cgacgccctc ctcgtcggac tcgaccgaca catggacatg
     5881 gcagccgcac acgagctgca cctgggtggg cagaccgaac tcccgcgcca tccacagata
     5941 ccggctgttc atggtgatcg tcgggctcac cggcaacggc gacgaggcca gcgccacgac
     6001 cgcgctgccg agcccctccg catggcgcgc cgcgtccttg cggcagcgga tgatctcggc
     6061 ccccagatcg gccatcgacg actgcggatg ggtggcgaac tccacctgct cgtcgtgcag
     6121 ctccttctcg aacacgtcct ggccggtgcc ctcctgcgcg gcccgcgcga gcaccgccgc
     6181 ggcctgtgcc cgcggctcgc cggtctcggg gtcgaccagc nnnnnnnnnn ggagttcctc
     6241 ttccactccg acggtacgca cgtcatcagg ccctttcgcg ctaggtggtg acagccgtgt
     6301 gccctcggac gacggcggaa cacctcaccg gccgacgtcc gggccggatc cgtgtacgcg
     6361 gtgtcgccac gggtacccgg gcggagcttc tggggtcgtg ccgggcaggc acggcgccct
     6421 gtccgccgcg acaggaggag aacgtgacca gccccaccga ggccggccga gtgaccggta
     6481 ccgccgacaa ggactacaac ctgatctggt ccgtcgaggc ctgtctgaac aacgcgctgc
     6541 gcctggagac gtacatcgag gacgcggagt gggagaagga caccgaggtg gccgagctgt
     6601 tccgcaaggc acaggccgac agccgcaagg gcgccgacct cggcaagcgg cttctgcacc
     6661 gacgcctgag cgactgacgg cccgacccgg gccgcccgcg gtgcgggaga ccatcggaca
     6721 gtccgttccc tgcatgcgcc attgtgggca cggccggggc cctcacgcga accggccgga
     6781 gcggtggcgc cgggaatgga cgtccgcccc gcgggccgcg gcttccccgg gcagagagac
     6841 cggaagcgac gaggcgcgga gagtccggaa acgacagagg caaggagtcc acgactcctt
     6901 gccacgctca acttatagcg caccgggggg cttgcggcaa gaccccgccc gtgccgcaga
     6961 atcgccgacc gaaacgcgaa tccgcgcaca tgggggtagt gatgatcgac gtgatcgtcg
     7021 tcggcggcgg gccgaccggg ctgatgctgg cgagcgaact gcggctggcc ggagtgggca
     7081 cggtcgtgct ggagaagctg accgagccga ccggcgagtc ccgcgggcag ggactgcacg
     7141 cgcgcagtgt cgagatcatg gaccagcgcg gactgctgga ccgcttcctc gcggtcagcg
     7201 agacgttccg ggtgggcggc ctcttcggcg ggatcatgaa accctggccc gacacactgg
     7261 acacgggcca cgcgtacggc gtggccactc cgcagccggt caccgagcgt ctgctctacg
     7321 agcgcgccgt cgaactcggc gccgacatcc ggcggggcag cgaactggtc ggactgagcc
     7381 aggacccgga cggcgtgagc gccgagctgg ccgacggcac acggctgcgc gcccgctatc
     7441 tcgtcggctg cgacggcggc cgcagcgcgg tgcgcaaact cctcggtgtc gccttccccg
     7501 gcgagtccgc cacggtggag acactgctgg gcgacatggc cgcgtccgag gatccggcga
     7561 cgatcaccgc tgtcgtcgag gaggtacgca aggccgagct gcggttcggt ctcgcccccc
     7621 tcgaagacgg gcactaccgc gttctcgtgc cggccgaggg ggtggcggag gaccggacgg
     7681 ccccgccgac cctcgacgag ttcagaaagc agctgcgggc gttcgcgggc accgacttcg
     7741 gggtgcactc accgcgctgg ctctcccggt tcggcgacgc cacccggcag gccgagcgtt
     7801 accgcgtcgg ccgggtgctg ctggccggcg acgcggcgca catccatccg ccgaccggcg
     7861 gacaggggct gaacctcgga gtgcaggacg cgttcaacct cggctggaag ctggccgccg
     7921 cggtccacgg ctgggcgccg gaggacctgc tggacagcta ccacgccgag cggcatccgg
     7981 tggccgcccg cgtgctggtc aacacccgcg cgcagatcac cctcctggca tccggccctg
     8041 gcccgaccgc gctgcggcag ctgctgtcgg agctgatgga cttcgaggag gtgaaccggt
     8101 acatcaccgg gatgatcacc gccgtcgatg tccgctacga cttcggtgag ggccatgacc
     8161 tcctcggtcg gcgcatgcgg gacgtgcggc tgaagcgggg ccgcctgtac gagctgatgc
     8221 gcgagggccg cggcctgctg ctcgacccga ccggcaccct ctcggtcgag ggctgggcgg
     8281 accgggtgga ccacgtcgtc gacaccgccg aggacctgga cgtccccacg gtgctgctgc
     8341 gccccgacgg ccatgtggca tgggccggtg aggacggccg ggaactcctc gaccggctcc
     8401 cgcggtggtt cggggccgcc accggctgag cccggtcgcg cgggaggcga ggtcgtacgc
     8461 ggcgggtgcc gaaggggcgg gccgcacgac cggccgccgg cggaccgttg ccgggaccgt
     8521 cccgcaccgc gcaggatgct gcgatgacct cgcctcccgc cgtacgcccg taccgccccg
     8581 gggacgccga cgccctccac gagatctgta tccgtaccgc ccacaacggc ggcgacagcc
     8641 ggcccttcca ctcggacccc gacgtcttcc cggcgacctt cgccacgccg tacgcccatc
     8701 tggaaccgga actgaccttc gtgctggacg acggccgcgg gcgggccgtc ggctacatcc
     8761 tcggcaccgc ggacaccccc gccttcgtgg acgccttccg cgcgcagtgg ctccccctgg
     8821 tcgccgagcg cttcccggcg cccctcggtc ctcccaccac ccccgacgag gtgatcgccg
     8881 agctgctgca ccgtcccgaa cgcatggtcc tgcccgaact cgccccgtat ccggcccact
     8941 tgcacatcga catccttccc gcccagcagg gccggggcca cggccgggcc ctgctgcgca
     9001 cgttcctgcg ggccctgcgc gcccgagggg tgccggccgt ccatctctcc atggtcaccg
     9061 ccaacacacc ggcccgtgcc ttctacgacc gcatgggctt tcacgggata gcggtcccgg
     9121 accccggccc ggtgacctac ctggggcgcg cgacgacgga gaacgaggag ccgccgggcg
     9181 ggacacgctc ctgactccgg ccccgcgcgg ctcaccgcac ggcggccaga acgtggctgg
     9241 gacccacctg ccagaccgct ccgacgtgct cgaagcccgc ctcgcgcaac agcgcgacat
     9301 ggccggacag agtcagatcg ttgccctcgc agcggggacg tgcgccgtcg tcgccacgcg
     9361 tgaggaaggg tgccagctcc gggtcgccgg ccgcgccgga ccaccaggag tcccagtcct
     9421 cggcgaggga ggcgccgccc cgggtggaca gggagagccg ctccgggccc atctcgtccc
     9481 gggcgatgcc gtggacgcgg tgcatcggcg cgacgccgat gcaccggccg cggaagcgcg
     9541 gatgggtctg gacatggttg acggtgccgc agtgcgcgcc gagcggatgc ggctcccggc
     9601 ggacgatgag ccagccggcg agcgagtccc cgacgacagc gacgagcagt ctgccgcgcg
     9661 cgggatgcag ctcgtggacg agtgagtcga ccacgggtgc gacgtcgtgg gcgctcaccg
     9721 gaagaggagg gaactcggtc gcgaggaccg cgccaccggc gttcgccacg gcctcccagc
     9781 agtcggcgat ctgctctctg agccccgggg tggtctcctc cgggctggtc aactgcaggc
     9841 acgtggagac ttgacgcacc gtcatgtcac tcaggctggc acaggcgccg ccggccgccg
     9901 ggattctgcc tgctccaggg ggtgagtcgt actcctccag gcggacggct tcggcgccgc
     9961 cgtcgccatg ccgccgcgac accaccgccc agcgcgggtc ctaccgggct ccgagcgtac
    10021 cccggggccc gcgcatgccc cgggcttcgc gtcgcgctcc cagcagcgtc cgtgccgtgg
    10081 ccggcacggg cggggacgcc gagccgcgca gcagcctcgc acctcgcgcg aacgccgcgt
    10141 cagcggtgag cagttcgatg tcgatgaccg tccgtagcag cactccaccg gggccctgcg
    10201 tgagcaccgg cagagccctc gccgcccgca ggcggacacg ggccgcctcg atctgatcct
    10261 ccaccaactc ccgtacgccc gacgactcgc ggccctccgc gagatcctcc gccgtgaccg
    10321 agaagcgctt cagcgtctcc gccgggatgc ccaggcgtcc ttccgggagg tcctcggcca
    10381 ggtcgttgac gaagtccagc cgctggctgc cctccataag cgtccggcag gccgcgcgga
    10441 accggccgtc gtcgccctcg gggcccagca gcgacgcgac cagcatgaac gcgggcagcg
    10501 agtaggcgtc cacataggcc tggtagtcgg cctcggtggt gaaaccggtg aactccagat
    10561 ccacggtcgc ggtgtccaga taccgctcca ccgccacgcg cagttccgga cgggccgccg
    10621 cactgttcag cagcgcgcgg atcaagggat cggtgctcac tcccgtctcc agcgcctcac
    10681 gcacctcccg ctcccacgac gcccacgccg agacccgcga ctgcttcggg ccggtgtcca
    10741 agaggtcgtc gctgtggtgc atcatcgccg tcgccgccac gacgtgcggc aacagcgccc
    10801 gcggcaacag caaccgggcg gcgaggtagg aggtgcgccg ggcacgcgcc accaggtccc
    10861 gctgtcggtc gtagtcccgc cgcgactccg gctcccgcac acctgctgcg tccaggctct
    10921 gcttccacgt gctcatacgc cgatcgtagg cggcacgccg aggcacgtcc gatgcccgcg
    10981 gacctgcccc ttcggctctt gcgcgagacg gtgcgcggga gcggaggcgc cgcgaccgcg
    11041 gtgatccgcg cgtgtaagga tgtcggcgcg aagacccggc ggggacatcg gagatgggac
    11101 gcaatgatcg ggaccgtgtt ccgcagtgag gacgtgccgg cggaggacag attcgacttc
    11161 tggcgagaac tgctcggcac gacacgggcg agcgaggcga tcagccctca ttcggcggac
    11221 ttctgggggg agttgcgcct gatggagctg ggcccggtga ccgtgtggcc ggcgtcgttc
    11281 ctgccctcgc gctaccggcg tgaccagcgg atggtgcgcc ggtccgaccc cgagctgtac
    11341 cacctgacac tgctgctgga cgggggcctg gccctcgacc acgccgaccg gtgcgacacg
    11401 ttcggcccgc gcgatctgca cctggccgac agttcgcggc cgtacgacat ccggtcggcg
    11461 gacggcgggg ggaccggggt catcaagggg gtgggcgtcg acttccccaa ggcgctgttt
    11521 ccgctgccgc cgcaccaggt ccgggagttg ctcggccggg ggctgtcggg ccgggagggc
    11581 ctgggcgccc tgctggcgga cttcctcatc ggcctggagc ggcaggccga ctccctccag
    11641 ccgtccgacg cggcacggct cggcacggtc gtcctcgacc tgctgtcggc ctggttcgcc
    11701 cacgcgctgg aggccgaggc ggccctgtcc ccagagacgc gtctgcacgc gctgacgcga
    11761 cgcatccagg cgttcatccg gcagaacctg cacgacccgg aactggcgcc accggtgatc
    11821 gccgccgcac accacatctc tctcagctac ctccaccgcg tcttccagca gcagacggac
    11881 ggcgagaccg tggccgcctg gatccgcgcc cggcgtctgg agggcgcggg ccgcgacctg
    11941 gcggacccgt ccctgcgcac cacaccgatc catgtcatcg ccgcccgctg gggcatgccc
    12001 cgtgcctccg acttcacccg cgccttccgt accgcccacg gaatcgcacc cagcgagttc
    12061 cggctgcggg cgttgtccga cgtcgatgag cgcggacact aggttgggtc catgtacgcg
    12121 acgcgggtct ccagacatgt gaacgcggca cgtgcggacg tgtaccgggc gctggtggac
    12181 ccggacgcga tcgcgcgatg gcgggtcccg gacggcatga gcggcgaggt gcacgagttc
    12241 gacgcccgtg agggaggcag gttccgtgtc tccctcacct acgacacgcc ggccgggacc
    12301 ggcaagtcgg cgtcccacac cgacacctac cacggccact tcgcgcggct cgtgcccgat
    12361 gaggaggtgg tcgaggtcct ccggttcgag tcggacgacc ccgcgctgcg cggcacgatg
    12421 acgatgacca cccggctcac cgacgcggac ggcggcaccg aggtcctcgt cgtgcacgaa
    12481 ggcatccccg acgccgtgcc ggccgccgac aacgagacgg gcacccgcat ggcactggag
    12541 aacctggccc ggctggtcga gggttcctag tcgcccgccg ggccggttcg ccgcctgcgc
    12601 ggcgaacggt cgtcatcggc cggacccgtg cgggaaaccg ctcctgttcc tctccgcccg
    12661 gcagccgtac gaccgtgacg agccccaccg agatcgtcga actcacccga accgcgacgc
    12721 gatgctcgcc cggctccgac gtcgaacgcg ccaccggttc ggggcgtgcc ctctccacct
    12781 ccgcgtggga ggccgagcgc cgaagtccgg gcccgccagt tccccgacga ggtcgggcgg
    12841 acctgaaccg ccgtgctgct ccagctcgga cacagccgat cccgcccccg cgcggcatcg
    12901 cgagtggcgc tcccctcaga cgggggtagt ggatcgaaag gctccggttc agggttgggg
    12961 catgacagaa ctgcagacct tcgtactgcc cccggtggtt gacggcagtg acgtggacaa
    13021 ggcactgggc caggcgctga tcgccgcctg gcaggcggac ggcatcttcc agatccaggc
    13081 gaccccggaa caggaagccg ccaccgagcg ggccctcgac gcctcccggg gcttcttcgg
    13141 ccgcccgttc gaggagaagt cagggcacgt gtccgacctc acctacagcg gctacgtcgc
    13201 ctcgggcgag gaggagacgg ccggggagaa ggacggctcg gagatctaca ccgtctgccc
    13261 cgacatcccc gaggacgacg cccgggcggt cgacaagtgg ccgtgtcacg gccccgctcc
    13321 ctggccttcg gagcagtacg ccgcgccatg aaggactaca tgggcgccgt gggcgacatc
    13381 ggcgagagac tgctccgcct ggtcgccctg ggcctcggtc tggacgacat ggaccacttc
    13441 acgaagctca ccgaggacgg ctggcaccac atgcgggtcc tgcgcttccc gcgggcggac
    13501 gccacctccg agcggggcat cggctcgcac accgactacg gtctgctggt catcgcggtc
    13561 caggacgacg tgggcggcct ctacatccgc ccgccggtac ccggcgagac ccgcggccgc
    13621 aactggctgg ccgacgagtc catggccggg cggtacgaga acgaggagcc ctggaccttc
    13681 gtcaccccgg tcccctcggt gttcaccgtc ttccccggtg acatcatgca gttcatcacc
    13741 ggcggtaccc tgctctccac cccgcacaag gtgcgcctgg ccgaccgcga gcggtacacc
    13801 atcgcgtact tccacgagcc gtccttccag gcggtcgcgc ggcccctgga agggagcgcc
    13861 ccggacgagt tcatccacta cgggacgcac ttcaccaaca tgttcatgcg ctgctacccc
    13921 gaccgcgccg ccaccgcgcg catcgagaac gaggaccgcc tcgccgtcct cgaacgcctc
    13981 cgcaaggagg ccctcaactc ctgaacggcg tagcgaggaa gccgtccggc acgtgccgga
    14041 cggcttcctc gggcgtccgc gccggtttcc ccgccgtcag ggcagcaggc ccagacggcg
    14101 ggccgtcatg accgtctcca tccgggtgtg gcagccgagc cggcgcatcg cgctgcgcag
    14161 atagctcttc accgtctcgg cgcgaaggcc gagttcgtcc gccacgtcgg cattggtgcg
    14221 tcccagcgcg acgcaggaca gcacgtcgag ttcgcgtgcc gagagagcgc tcggggggtg
    14281 ggaggcgggg gccccggtgc cggcgccggc cagtttgtcg cacactccga cgacccggtc
    14341 gcgcgcctcg tcgtccggga gtcgctgggc gaggatgcgc agctccgcgt aggcctcgcg
    14401 gatcgtctcc caccgggggg acgtgggacg ctcggacccc tcggcacgct ccgaggaagc
    14461 gcgcaggccg tcgaggcggc gcatcacctc gtcccgcacc gcgaggctct gctccagatc
    14521 gcgggcggcc cgcatgaccg agtcgacggt ccggtcgccg agggccacgg accggcggac
    14581 cgcgccgtac atgaccgcgc gcaccgtccg gttcaccacg acgggcgcgg ccacgacggc
    14641 gtggatgccc tccgccgcga ccatgaggtc gtaatggtgg ctgatctgct tgcagttcgc
    14701 gtagtcgttg acggcgatgg ggcggtgcag ggccaccacc ttgccgccga gccccatgcc
    14761 gaatccgaga gtcagtccgg acagggcatt ggtgtcgttc cccgtgaact cggtgagctg
    14821 cgcgtgccgg cccctgacga cgacgccgcc gaaggcgagg tccactccgg cggtgtcccg
    14881 taacgcctgg acaccgcgtt tgacttggcg gtcgtcgtcc ggaacggggg gtgatgtcag
    14941 tgtcattgcg gctacctcga tctgcccggg ggcagaagta cgccccctgc ccgcgtcgtg
    15001 cgcgggcctc gtgcgggagt ggtgcggtgt ggcgactgat gtgagcgtgt acctgggtgc
    15061 tgtccaagaa caaggagcgg acaacggccc cgcgtccaca gggccttggg ccaccatgag
    15121 ggagagcggg tccgtccagc tacccccgtg tgaggggggt gcgcaggcga catacccatg
    15181 tgtaccgggt cgaagtcgag ccgggaacaa cacggtccgg cagggttgcg accgtccggg
    15241 ggtgtgcgtg cacgtgtcac cgccggactg tgctgacgct tcgtcaacta cgttttcctc
    15301 ggaggctctt gacgtacttg agacttctac agaactgttc ttccgacgac gggggagtcg
    15361 gcgcgttccc cactgtcggt cagacaagga gtcgacccgg tcgtgctacc ggcggaagac
    15421 agcgaagagg cggcggccgc ccgcgccgcg gtcctggctc tgcgcaggga gagcgggatg
    15481 tccgtcgccg gggtggcctg ggtcgtcggg ccggggcagc tccggatcgg cgagacgagc
    15541 ggggtgagat cacgggaccg ccgggggctg tccgtgccgg cgggtgccgg actgatcggc
    15601 aaggtgctga cgaccggccg gccggcggcg gtgagcgact accggtcggc tcggcggatc
    15661 agccatgagt acgactcctt cgtctcggcc gagggggtgc gggcgatggc ggcggcaccc
    15721 gtgatcgtgg gaaccacggt ccgggcggtg ctcttcgtcg gatcgcgcga cgcggtacgc
    15781 ctcggcgacc gggtgctgac ggcggtgacg cgggcggcgc gcgatctgga gcagttcctc
    15841 gcgtgccagg agcaggtcca ccggctgctg tcggaggcca gggccggccg cgtcggcacc
    15901 gcgccccgcg acgacaccgc ctgggaacgc gtccacgagg cccatgcaga cctcctggaa
    15961 ctcaccgccg ccctcgacga cggacacctc aaggagcgtt tccacgaggt gtgccgtctg
    16021 ctggagcggg gctgctgctc cgaggggccc ggggaatcgg tgccggagag gccgtcgcgg
    16081 ctgtctcccc gggaactcga cgtcctcacc gcggtcgccg cgggctgcac caacctcgac
    16141 atctccgccc ggctcgacat cggcctggag accgtgaagg gccatctgcg ttcggtcatg
    16201 cgcaaactgg gcaccaccac ccgcttcgaa gcggtcaccg cggcgcggcg cgctggcctg
    16261 ctgccgtgac ccgggcgggt ccgccgctca atcggccgcg gttgccccgg caggacgccg
    16321 aggcccggca aggtccgccg gtcccgtcag ctccggtgtg tgacggcgac ccgcacgatc
    16381 agcgtgcccc tgttgtcctc ggagcaggag ccggcggcgt cgttcatgcc caggtgcagg
    16441 gtgccgtccc cggtggccac gaaggtcagc ttccgtgcga cggtgtggac ggggaacttc
    16501 cggtcgccgg tgaggacggc gaggagcgtg ccgaagggcg ccgccgcctt gaccttgcag
    16561 tccttcgcgc cgtcgagccg cgcgttggtg gccgcgtcgt agccggccgg tccggtcatg
    16621 ggcatgttgc gatggtcggc cgtccattcc cccgacacga aacgcacggt gacccggtcg
    16681 ccccgccgca ccgcgactcc ggtcaccggc tgccagccgg tcgccgactg cacgacatgg
    16741 ctgacggtcg tcgtggtcgg ttccttctcc aacggcagca atccggagag gaacagaccg
    16801 cccgcaccac ccgccgccag caccgccgtg ccggccaggg cccaccacag acctttgcgt
    16861 cccgccggac gcggcgaggg cgcgggcgac gaggcgtgcc cggcggtcgg cacggtccgc
    16921 ccggcccgga cgggccgtcc ctggccgccg gtcacggtgt cggcgtcggc cgacgaggcg
    16981 aaggggcggg ggacacgcac ggtcgccgag ggcagtggcc cggcgtcggt ctcgcccgcc
    17041 gcgacgcgcc ccagcgcggc ccgcacgccg gccgccgaag ggcgctcgcc gggggatttg
    17101 cgcagcaacg cctcgacgac cggccgcagc gggccgagcc gctccggcag gacgggctcc
    17161 tcgtacgcca cggcgtgcag ggtcgcgggc ccgcccggcc tgcggaaggg ggactgtccg
    17221 ccacagaccg tggcgagcgt cgcgcccagg gaccacaggt cggaggcggg gccgctctcg
    17281 gtccccgtca cccgctcggg agccatgtac tccagggagc cgaccagctg gccggtgccg
    17341 gtgaggaact cgccgtcgtc cagggcggcg atcccgaagt cggtgaggac ggcgtcgtcg
    17401 tcgcggcgca gcagcacgtt ggccggtttg acgtcgcggt gcagggcgcc cgccgcgtgc
    17461 acggcctcca gcgcggcgag catctgcagc ccgagggcgg ccgcgtgccg gggggtgagc
    17521 ggtccgccct gggcgatccg gccggccagc gacggccccg cgacgagttc catgacgatc
    17581 cacagccggt cctccgcctc gaccaggtca tggatgccca ccacatgcgg gtgcggtacc
    17641 cgggcgaccg cgcgggcctc ccggaccgcc cggcgcatcc ggacgcggtg ctcctcgtcg
    17701 ccgtgggtga ggatgtgcag ttccttggcg gcgacgggac ggtccagcaa ctggtcatgg
    17761 gcgcgccaga ccgtgcccat accgcctctg ccgagaacct cgtggagcag ataccggccg
    17821 gcgatcagcc gttccgcacc gtgctgcgca cgtgtcgccg tctggtcgtc gccgtgtccg
    17881 ggtgtcacgc gctctctcac gtttccttcc cggcggacgg ggcgtccacc ggtgtcgtcg
    17941 ctcgttcggt ccgtcgtcat gtgttcgaac ggcgcgagca tagcggagag tgaggtcgtg
    18001 gcggcgtgtc aactgcggtg ccggacaagg tctttgaggc gacgagcgga agcgcgcagg
    18061 tccgggtccg ggcgcaccgg ggcgcccgga cccggacggg tcagcggggc tgtcgtgccg
    18121 ccgctacttc ttccacgccc agtgcagacg gtcgagcccg ctctggttgt tgaccttcag
    18181 gctgaggcgg gtgcccgtgc cctggagggt ggtcagcgag taggtgtcgc cgttgcgcag
    18241 gccgggccag tagaccgagc cgagacgcag ttcccggatg acgtcggtgg cggcctggat
    18301 gtaggcgacc tcgttggagc cgttgaccgg gccgttgtag tccaggccgg tcgtcatgga
    18361 agcgccgaac tcgtccagga tcgtgcgcga ggcgcaggtg ccgatgcgct ccttgaagtc
    18421 cgccttccac tggtcgacgc tggtccagtc ggtgtgccag aagccgtagt tgtgcagggc
    18481 gatccgggta ccgtcgagcc gcttgtcggc gcagaccggc ttgacgtcct cgctgtactt
    18541 gtaaccaccg atcaggaccc ggtcgcgggg gatggagcgg tgcttgtcca gccagcgggc
    18601 ggccacgtcg cgccactcct gggaggtgta gccgaacggc tcgttcatcg gctcgaagta
    18661 cacctggccg ttgtggccgt aggcggaggt gatccgccgc cacatccggt cccaggtcgc
    18721 ctggtcgtcg atcttgccgt ccttggcgtt gtcggcctcc cagtagccga ggacgacctt
    18781 gaagcccttg gcggtggcgg cgtcgatcgc gccccggtac gacttccaga aggggccgtt
    18841 cacggaggtg gggttgaccg ggaggcgcac cgtgttggcg ccgagcttgg agaacccgcc
    18901 gatgatcgcc ttggacttgg cgtaggtcgt ggcgtagccg tcggtggtgg acaggcccga
    18961 gggcacgacc gcgtcgtcgg cgtagttgtc acgcgggtcg gcccagttga cgccgcggaa
    19021 ctcgctgacg ggcggcggcg aggcgtggtg gggggcggcg ggagcggcgg acgcggggga
    19081 ggcgacgagt ccgccgaacg ccgtgacgcc ggccagcgac gccgcgaggc aggctgtccc
    19141 gcgatggttc tttagtggca ccagatccct ttctgggcag ttgcgtccgc gaaacctgga
    19201 agggcaggtc ggcggatctg taactcccgc aaagtagaag agatctcgaa cagaggtcaa
    19261 cacatctgca caccaaattt catcaagaac acagagctag gggccgccca cggccagctc
    19321 cgatccggtg agccgcaccc ggatgccgtc ctcctccacc cggacgtccc gcagacgcat
    19381 gctcccgcgc tccggctcgg gcagttggaa ggacagggac agctggtcgg cgaggacggg
    19441 ccgggtgagc cgggacagag cgttcaggag gttggggtcc aggcccaggt cgcgcagcag
    19501 agcggggttg tccagggcga gatcgatgag gttgaggctc cgggcctggc gcgcgaaccg
    19561 cggtgagccg gtgacttcgg cgagttcgcc gtcgtcgctc agggcggcgc gcgcggtcgc
    19621 gtcggacacc cccagccgct tcacgatcgc cgggaccgac agcagcgcct tcgccctgcg
    19681 ggtctcccgg gcgaggccgg cggccgcctt cggtgtcaga tgcagaccgt ccgaggcgcg
    19741 cgtgccgggg cgataggtgg caaggtcccc gatgtccagg cgcatgccgc cgatccgtgt
    19801 ggcgataccc cgctcgccct cccgctggat cgtggcctcg gcacgcagcc gcagatcacg
    19861 tccggcgacc ggcagggtgc cgcgcgcccg gacccggtcc cggccgtcac cggtgaacgt
    19921 cacctgggac gcgccgagtt cacgattgag gtcggcgaac gacagcagca catcgccgtc
    19981 gagccgcggg acgcgggcgc cgcgcacgga ggtgaggccg tcggcgtcca gtcgtacgtc
    20041 gtgggccgtg gccgacacct tcgccagcga cacccggtcg gccgccacgt ccggcacggt
    20101 cacccgcacc gagtcgagcc gcttgccggc gagttgggtg aggaagggga atccgccgat
    20161 ctccacctcg ggtgcggcgg ccaggtccag ccggtcctcc agggtgtccg cggcccggtg
    20221 ttcggcgtac aacacggccc agcggtcggc gagggtcacg aaggaggcga ggacgaccat
    20281 gcccaccacc gccttcaccg cgaggggcag ccccgtgaat cgcccgcgtc cgcgtcggcg
    20341 tcggccgccg cgacggtgaa cgggcggagt ccactccggc tcccgctcgt ccccctgccc
    20401 ggtgggcgct cgggtggtgt cctcgtcgaa gaagtcctcc agcgaagtcg cttccagcgg
    20461 gccgtcgtcg agggtgccga gttcgtcgta cgggttgcgg ggcgcggtgg agcggtcgag
    20521 ggccggttcg tgcggatctg tgcggtgggg ggagcgcatc gtctcatccg aacatgtgca
    20581 ccacccctgc ccgcaactcg aaccccgggt atgcgatcta gttcacgatt gcgacgcggc
    20641 gtcggcgcgg gcccgccaca ggtcgcgcag cagggcgatc tcggccatgt ggtggatgaa
    20701 ttcgaggttg ctccccgcca ggacgcccac gaacgggtcg tgcggggcgg agccgtacgg
    20761 atactgcgag aagccgatcg tgtcgagttg ctcgtcggtc acgccggcga cgcttgcgcg
    20821 ccaccggtcg acgacgggcc agaaccggtc gagtgccgag gcggcggacg gctggaaatc
    20881 gaccgccagc ctcggatcct gtcgccgtcc gccgaaggtc cactcccagc cgcccg
//
