LOCUS       NZ_CPTT01000016        13008 bp    DNA     linear   CON 13-DEC-2024
DEFINITION  Streptococcus pneumoniae strain 10F/2, whole genome shotgun
            sequence.
ACCESSION   NZ_CPTT01000016
VERSION     NZ_CPTT01000016.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  AUTHORS   Informatics,Pathogen.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2015) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001138385.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 01:30:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 60 of 139
            Pseudo Genes (incomplete)         :: 78 of 139
            Pseudo Genes (internal stop)      :: 32 of 139
            Pseudo Genes (multiple problems)  :: 26 of 139
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:01:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 35592
            Orig. end                         :: 48600
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CPTT01000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13008
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..13008
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13008
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:8099](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..8099)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(1065..1075)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(1821..1835)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.98"
                     /tool="antismash"
     misc_feature    2533..2546
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.09"
                     /tool="antismash"
     gene            complement(2617..2751)
                     /locus_tag="AEH42_RS12380"
     CDS             complement(2617..2751)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429437.1"
                     /locus_tag="AEH42_RS12380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_000429437.1"
                     /transl_table=11
                     /translation="MENLRLSTKRTQAEKVPQTFSLCRELGEPTDVYEIVWEKLQGLK"
     gene            complement(2762..3469)
                     /gene="purC"
                     /locus_tag="AEH42_RS07560"
                     /old_locus_tag="ERS011481_01469"
     CDS             complement(2762..3469)
                     /EC_number="6.3.2.6"
                     /GO_function="GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="purC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312208.1"
                     /locus_tag="AEH42_RS07560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01469"
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="WP_000043300.1"
                     /transl_table=11
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAGK
                     GVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSKRF
                     GVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINELLKV
                     WFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLGELTD
                     VYEIVWEKLQELK"
     gene            complement(3639..4988)
                     /gene="comB"
                     /locus_tag="AEH42_RS07565"
                     /old_locus_tag="ERS011481_01470"
     CDS             complement(3639..4988)
                     /codon_start=1
                     /gene="comB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /locus_tag="AEH42_RS07565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01470"
                     /product="competence pheromone export protein ComB"
                     /protein_id="WP_000801625.1"
                     /transl_table=11
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEM
                     SLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESYAS
                     QLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQNETI
                     ASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGE
                     ENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKV
                     GQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEGALLAQL
                     YPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTE
                     KGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(5001..7154)
                     /gene="comA"
                     /locus_tag="AEH42_RS07570"
                     /old_locus_tag="ERS011481_01471"
     CDS             complement(5001..7154)
                     /codon_start=1
                     /gene="comA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /locus_tag="AEH42_RS07570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01471"
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="WP_000668287.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.9e-44, bitscore:
                     140.0, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1125.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKTT
                     MDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTGQD
                     KDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPILVK
                     QRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQIL
                     SYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALAS
                     TILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNRDTMEAN
                     AVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAH
                     LLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRL
                     NEVYLVASEFEEKKTVEDLSLMKGDMAFKQVHYKYGYGRDVLSDINLTVPQGSKVAFVG
                     ISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQPYVFNGTILE
                     NLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARA
                     LLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGK
                     IVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(7741..7866)
                     /locus_tag="AEH42_RS12165"
                     /old_locus_tag="ERS011481_01472"
     CDS             complement(7741..7866)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /locus_tag="AEH42_RS12165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01472"
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="WP_000346297.1"
                     /transl_table=11
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            complement(7869..8099)
                     /gene="blpU"
                     /locus_tag="AEH42_RS07585"
                     /old_locus_tag="ERS011481_01473"
     CDS             complement(7869..8099)
                     /codon_start=1
                     /gene="blpU"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /locus_tag="AEH42_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01473"
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="WP_001093068.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.5e-17,
                     bitscore: 55.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKKMSQFEIMDTDMLACVEGGGCNWGDFAKAGVGGGAARGLQL
                     GIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     misc_feature    complement(8068..8082)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.48"
                     /tool="antismash"
     misc_feature    complement(8226..8239)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.29"
                     /tool="antismash"
     misc_feature    8247..8260
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.31"
                     /tool="antismash"
     gene            complement(8302..>8601)
                     /locus_tag="AEH42_RS07590"
                     /old_locus_tag="ERS011481_01474"
                     /pseudo=""
     CDS             complement(8302..>8601)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="AEH42_RS07590"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01474"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LEMRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLIAEDK
                     AYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     misc_feature    8569..8584
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.17"
                     /tool="antismash"
     gene            complement(8638..8871)
                     /locus_tag="AEH42_RS07595"
                     /old_locus_tag="ERS011481_01475"
     CDS             complement(8638..8871)
                     /NRPS_PKS="Domain: PP-binding (8-72). E-value: 3e-11.
                     Score: 35.5. Matches aSDomain:
                     nrpspksdomains_AEH42_RS07595_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /locus_tag="AEH42_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01475"
                     /product="acyl carrier protein"
                     /protein_id="WP_000136447.1"
                     /sec_met_domain="PP-binding (E-value: 3.7e-12, bitscore:
                     38.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 1.3e-05, bitscore:
                     17.1, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEFI
                     LTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     aSDomain        complement(8656..8847)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AEH42_RS07595_PP-binding.1"
                     /evalue="3.00E-11"
                     /label="AEH42_RS07595_PP-binding.1"
                     /locus_tag="AEH42_RS07595"
                     /protein_end="72"
                     /protein_start="8"
                     /score="35.5"
                     /tool="antismash"
                     /translation="RIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEFILTLEDEFS
                     IEISDEEIDQLQNVGDVVK"
     gene            complement(8877..9869)
                     /gene="plsX"
                     /locus_tag="AEH42_RS07600"
                     /old_locus_tag="ERS011481_01476"
     CDS             complement(8877..9869)
                     /EC_number="2.3.1.274"
                     /GO_function="GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="plsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /locus_tag="AEH42_RS07600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01476"
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="WP_000717458.1"
                     /transl_table=11
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIKQ
                     YLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTGAL
                     LAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSFYAK
                     NVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVADVVV
                     ADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLNYSDVG
                     GAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(9866..10636)
                     /gene="recO"
                     /locus_tag="AEH42_RS07605"
                     /old_locus_tag="ERS011481_01477"
     CDS             complement(9866..10636)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /locus_tag="AEH42_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01477"
                     /product="DNA repair protein RecO"
                     /protein_id="WP_000616162.1"
                     /transl_table=11
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQSK
                     LAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADASLQ
                     DNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVGQAF
                     DFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQELRQF
                     MDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(10633..11802)
                     /locus_tag="AEH42_RS07610"
                     /old_locus_tag="ERS011481_01478"
     CDS             complement(10633..11802)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (31-382). E-value: 2e-63.
                     Score: 206.6. Matches aSDomain:
                     nrpspksdomains_AEH42_RS07610_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /locus_tag="AEH42_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01478"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_000366370.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.4e-63, bitscore:
                     206.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 5.9e-09, bitscore:
                     26.9, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.6e-09,
                     bitscore: 27.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTTP
                     DHVKEAGKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATEAL
                     SATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAILEQ
                     GDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAHVSLG
                     TMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQHAAVEA
                     LTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQDSFAFLK
                     DFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     aSDomain        complement(10657..11709)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AEH42_RS07610_Aminotran_1_2.1"
                     /evalue="2.00E-63"
                     /label="AEH42_RS07610_Aminotran_1_2.1"
                     /locus_tag="AEH42_RS07610"
                     /protein_end="382"
                     /protein_start="31"
                     /score="206.6"
                     /tool="antismash"
                     /translation="VLRLTLGEPDFTTPDHVKEAGKRAIDQNQSYYTGMSGLLTLRQAA
                     SDFVKEKYQLDYAPENEILVTIGATEALSATLTAILEEGDKVLLPAPAYPGYEPIVNLV
                     GAEIVEIDTTENGFVLTPEMLEKAILEQGDKLKAVILNYPANPTGITYSREQLEALAAV
                     LRKYEIFVVCDEVYSELTYTGEAHVSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPA
                     TFTAQLIKSHQYLVTAANTMAQHAAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGF
                     EIIKPDGAFYIFAKIPAGYNQDSFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAAS
                     METIKEAMKRL"
     gene            11951..12961
                     /locus_tag="AEH42_RS07615"
                     /old_locus_tag="ERS011481_01479"
     CDS             11951..12961
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /locus_tag="AEH42_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01479"
                     /product="YeiH family protein"
                     /protein_id="WP_000009140.1"
                     /transl_table=11
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLLH
                     PFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALIIA
                     YLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVLAAL
                     IFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLTRTLA
                     IIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSFFTPLK
                     ELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIGIF"
ORIGIN
        1 tatggtcagc ctggcttgct tcaaactgag caaaattttt cttaatcaag tcaaaatcaa
       61 tctctgcaga gagggcttga cctgggatgt agtagatatt ttccccaaca gctttaaatt
      121 ctggagagag caccttacgg ctatctgccg tcgtcacccc aaaggcaacc aaggttggcg
      181 gaacggtcaa ttcttcaaag gtaccagaca tggagtcctt accaccgata gatggcaagc
      241 caagttgaat ttgtgcttca atagaaccta gaagagcagc tactggctga ccgaaacgct
      301 ctgcttgttt atccatacgc tcgaaatact cttggtaaga gaaacgagcc ttggaccagt
      361 tggcaccagc agccaccaaa cgagcagttg cttcgataac cgcataagca gcaccgtggt
      421 atggagacca ttcagctaca tatgggttga aaccttgagc aatgaccgac gcagtatgag
      481 tcacaccgtg ttgaactggc aatttctgca cagatgcctc agttggtgtg agttggtaac
      541 gaccaccaag tgggtgatta accgttgagc gtccaacaga gcagtcaaag acagtctgta
      601 atcctttttg acttgcatgg ttgaggtcag atagaaccgt aagggtatct gattccagtg
      661 tttcagcaga tgtttgacgc tcttctggga gtttgacatc cttgtccaca actttggcat
      721 cgacaaccac gcgcacacca ttggtgtcaa ggaaacgacg ctccaagtca acgattgtct
      781 caccattcca gtgcatgaca agatttggtt tttcagttac tgtcgccacc acaacagcat
      841 caatattttc tttgttacat tcggcaacga aggcatccac atcttcagga cgaaccacga
      901 ccgccatccg ttcttgtgat tcagagatgg caatttctgt accattcaag ccctggtatt
      961 taagaggcac cttgttgagg tcgatttcaa gaccgtctgc caattcaccg atagccacac
     1021 agacgccgcc tgcaccaaag tcattggact tcttgatcag acgagtgaca ttgccattac
     1081 ggaagaggcg ctgaatcttg cgttcttcga tggcatttcc tttttgaacc tcagcaccag
     1141 cagtctctac agactcaact gtttgaacct tagaagagcc cgtcgcacca ccgacaccat
     1201 cacgacctgt tttgcctccg agaaggatga tcacatcacc tgcttcaggt ttttcacgga
     1261 caacattgcc cttgggagcc gcaccaacaa cggcaccaag ttccatacgt ttagctacaa
     1321 agcctgggtg gaagtattca cgaacgtagg ttgtggcaag cccaatctgg ttaccatatg
     1381 aagaataacc atgagctgct gttttagaaa tgacttgttg tggcaatttc ccagcacgag
     1441 tttccgaaat cggtgctgta atatcaccag cacctgaaat acgcatggct tggtaaacat
     1501 aggaacggcc tgacaacgga tcacgaatag ctccaccaat acaggtagcc gctccaccaa
     1561 atggctcaat ttctgttgga tggttgtggg tttcgttttt aaacatgagg agccaaggtt
     1621 ccttgacacc atcaacgtcc acttcaattt caactgagca ggcattgatt tcgtcagaga
     1681 cttccatatc atccaatcgt ccattagcac gctcataacg accgaaaata gtcgccatat
     1741 ccatcaaggt ttgtggtttt tcagaccgac ctaattcctc gcgcatggca atatacttgt
     1801 cataggttga ctgcaattgc ttttgaaatt tagaagctga aaagtcgatg tgtttcaact
     1861 ctgtctcaaa agtcgtatga cggcagtggt cagaccagta agtgtccaaa accttaagtt
     1921 cagtctcagt tggcacgcgc ccgattgact taaagtagtc ttggataaag agcaaatcat
     1981 ccacttccat ggccatccct tgttcggcct tgtagcgagc aaagtcttct gctgtatagc
     2041 tttcaaagaa agtcaatttt ggaatggtct tgtctgactc tgaaaactcc tgcttggcaa
     2101 tccctgtcgt gatatccttg aaacgagaat caactggatt gagcaggtag tttttgacag
     2161 ctttcaactc agtcgcatca atatctttat tcaccaagta aagttgggct gtgttgactg
     2221 tcacgtcact cgaacttccc aacaaaagca aggcttcctg tgacgaagct gcacgctggt
     2281 caaactgccc tggcagactt tcaatggcaa agaaagcata gttagcaaga tccgcctgca
     2341 cagatacttc atctaaaaca tggtcggtta cctgctcaga gaaaatgtgc ttctctgcag
     2401 gtgcaaacaa gtcctcaacc aagtcaaata catcatatac ttgcacaata cgaatacttt
     2461 tcaagcttga tagtcccaag ttgtgctgga gttctctaac caaactctct gacttgacct
     2521 gaaaatcagc ctttttttca acaaaaatac gtttatccat caattcttat tcctttattt
     2581 cagctcttgc aatattccca aacagccttg aggttgttat tttaaaccct gcaacttttc
     2641 ccagacaatt tcgtaaacat cggttggttc acctagttct ctacagagtg aaaaggtctg
     2701 ggggaccttt tcagcctgag tccttttagt tgagagacga aggttttcca ttgcaaacag
     2761 attatttcaa ttcctgcaac ttttcccaaa caatctcata aacgtcggtt agttctccca
     2821 atcctctacg gaaaacatcc ttatccatgt ggttgccatc agcatcccac aagcggcagt
     2881 tatctggtga aaattcgtct gccaagataa tcttgccatc cttgtcaaaa ccgaactcta
     2941 gcttaaagtc aatcaattta agcccaatct cagcaaacca gactttcaat agttcattga
     3001 tacgacgcgt ttcttccttc aagtaggcaa tctgctggtc atccgcaatc tgtaggaatt
     3061 tcacatgctc atcattgata aatggatcat ccaaatcatc atttttgtag taaaattcga
     3121 caatcggagt ctccaaggcg attccctcat ccacaccaaa acgttttgaa aaggaaccag
     3181 cagtatagtt gcggagcacg acttccaaag gaataatctt aaccttttta ttgagttgtt
     3241 ccgtgtctga aagtttctcc acaaagtgag tcgccacacc agccgcattt aatttctcaa
     3301 aaataaaaga tgagatctga ttattcaaga ctcccttacc tgcaatctgc tccttcttga
     3361 caccgttgaa agcagtcgcc tggtccttgt aagttgaaat aataagattt tcatcctcag
     3421 ttgtatagat atctttagct tttcccgaat agatcaattg ttttgacatt ttaaagttcg
     3481 cctttcgtat tacttgagca cattttacca caaaaaacca aaaaacacaa gaatttaacc
     3541 gaataaatag cagatgtttt tcaaaaaatg taaagaaaaa actgcaagaa gaatctttct
     3601 cacagtttaa aaattattta actctaaaaa cacgaacatt actctttgtt caaaaattga
     3661 tccaaataat aacgtagata acttttcttg cccgtaatca tctgcaagcg gccttccacc
     3721 ccgtacctaa gtttttcagc ctgctccgaa gttagattag tctccgcctc gattttaaag
     3781 aaattccctt tctcagtctt agtagctgtc gcatcaatac ttgtaatagt agaatctaga
     3841 aaaagttgat tcccggcatc atgagtcgta gtatagcgaa cagaatcacc gaccttgatt
     3901 cttgctacat cttttgaact tagataggct gtgagtttgg ctttcccttc tctttccaaa
     3961 gatggataaa gttgggctag tagggcacct tctgcaacca tgctagaatc actggtctca
     4021 ggattaagat gaagcacccc atcctcactt gccgtaattt tccccttgtc taaaagattt
     4081 ccctgtacct tcttacctga ctctgcctcc aagattttct gggctagaag ggtcaattcc
     4141 tgaccaacct ttgccaagtg ttgggattta agggattcca attgactgct taaccctgac
     4201 gcataggctt gctgggtacc tgaacctgca tactggacac ggtaagtagc aagactagat
     4261 tctaactgag aaatctgtgc ttcaacctgt gcaactgcct gaaccttagt ttggggattt
     4321 tcctcgccct gagacttgta ggactggtaa agagagtagg ctagattctg accggccaag
     4381 gaagcacctg tttcaatagc tgacttagct gtctggtaat cgcgaatttt agcctctgtt
     4441 tgactgatga ggttgccgat ttcggattgg gtttggctag ctgctgcatt ctgggacgcg
     4501 atggtctcat tttgttgcga tgtactagcc ctaagactgc ctgcttgact gatgtagtcg
     4561 cgaaaggtgg cttggtagcc aaacttatcc tcctctggaa agtggttctc cccttcttgc
     4621 aggctctttt gcagatactc caattgcttt ttttgatcct ttagcatgtc caactgactg
     4681 gcataggact ccgcttggac accctctgcc ccttcttggt attgaaccaa aagatccccc
     4741 ttcttaacca gcttattttc ttccaaatga ttgacaagaa tacgattgtt gctagttgac
     4801 tggatatttg caaggatacg actaggttcg acagtagctc tagtggacaa actcatctcc
     4861 ttttctgcaa cagttgcaaa gccaagtaaa aacacgagca gaagggccat gggtacaatc
     4921 acactactgg aaaaattatg gtaacgacga ttataaaact ccgcactttc taaaaattct
     4981 ggtttcatcc tctcctcttt ctagctattg accaaatggg cgtaaaagcc accctgtgca
     5041 agcaaatcag catgctttcc ttcttcgaca atcttgccct gatccaagac aactaccttc
     5101 tctgtccgct cagcaatagt caagcggtga gcaatgaaaa tcaaggtctt gtccaaagcc
     5161 atgagattat cgacaatccg cttctctgtc aaaatatcca aactgctagt cgcctcatcc
     5221 aaaatcaaga ccggcgcatc tgtcaagaga gcacgcgcca aagcgattct ctgacgttga
     5281 ccacctgaaa tccctgcccc atccgaagtc aattctgtct ggtaattcag tggcatgcgc
     5341 tcgatatcct ctcgaatctc tgccaattcg accgcccgta agatatcttc ctgtgtcgtc
     5401 ccctccttgg ctcccaaaag aagattctcc aaaatcgttc cgttaaagac atagggctgt
     5461 tgaggcagat agttgatgta ctggcgcagg gcttttttat caatctgatt gagattgaca
     5521 ctacccagac taatctcccc ttgacttggg tcgtaaaaat taaccatcat cttggccaaa
     5581 gtcgtcttac ctgaccctga aatccccaca aaagccacct tagacccttg gggaacggtt
     5641 aaattgatat ccgacaagac gtctcgacca tagccatact tgtaatgaac ctgcttgaag
     5701 gccatatctc ccttcatcaa gctcaaatcc tcaactgttt tcttctcctc aaactcagaa
     5761 gctactagat acacttcatt tagacggtta ttggcaacct gcgctgtctg aagcttggtt
     5821 tgcagattga tgatattttc caaaggattg gtaaagtaaa ccagcaaggt attataggta
     5881 atcaactgcc ccaaactcat cttgccatcc atgaccagaa cagcccccat ccagagaatg
     5941 ccgacattaa gcaagagatg ggcaaccttt ttcagagcct tttgctgact ctctgctcga
     6001 ctataggtaa aggatttctt cagataatcc acaaattcct tgtcaatttt ttggtaacgc
     6061 tgactttcac tggtcaagga cttgatagtc tcaataccgt tgatgtcctc aatgatagaa
     6121 gaagacagaa ccgcattggc ttccatggtg tcccgattca tcttttcaaa cggcttcata
     6181 aaggcaaaga taatcactgt gtagatagga agcgccaata aagtcatgaa aaagagattg
     6241 gtattttgtg aaaataaaac aagggaaata atgacaactg ttgacacatc taggaaaatc
     6301 gaaagaatgg tcgaagccag cgcatcgata atactgttag catctgtaaa acgagacacg
     6361 atctcccctg tcctgcgtgt cgcaaagaag gacataggga ggtgaaaaac atgcttgata
     6421 taggacaaaa tcacgtcaat cgacaagcgt tgccccaaaa caagcaagag atactcctga
     6481 gcgtaagaca agatttgctg gaggatgtag acgatgacta gcccaataga aataatccct
     6541 agtgtcgaac gcatctgatc tggcacatag gtatcaatga tagactgcag ataataagaa
     6601 cccacaatgt taatcacggt taccaagagt gttgccaaaa cgatattggc aatcaagcca
     6661 cgctgcttca ctaatatagg gataaaagag agcagaccat ttttttgttc cttatgaggc
     6721 ttatagtctg gactaggcgc cataaaaaga gtcactcctg tccattcttc ctcaaaacgc
     6781 tcacgtggca gtttagtcaa cttcaccccg ggatctggat cggcaatatg aatgctatcc
     6841 ttatcctgcc cagtcaccac atagtagtga agcaatttcc cttccttaag cacatgggca
     6901 acaaaaggaa aagtcaaatc cggcaagtca aaaagcgtca tatccgcctt aatggctcgc
     6961 gtctcaaaac caatctcctc tgccaccttg accaagccca aagccgtcgt cccatccatg
     7021 gtcgtcttag ccaattctcg caagtgagcc aaaaaataat aactaccata gtagccaaaa
     7081 accatggcta atgaagctac accgcagtcc atctgatcca cttgcggacg atagtgacgt
     7141 ttcccaaatt tcatattcat ctccttttcc ctaatactca atgaaaatca aagagcaaac
     7201 taggaaacta gccgcaggct gctcaaaaca ctgttttgag gttgtagata ggactgacga
     7261 agtcagtcac atatatacgt caaggcgacg ttgacgtggt ttgaatttga ttttcgaaga
     7321 gtataaactc atctgataac aactatctta cctcaatcac taaacaaaaa ctggacttcc
     7381 ttcccaaatg agcctatctc cctcccaact gcactttttg gataaaaaaa taggcagaac
     7441 aagagtcctg cccactaaaa atatgctatt gaaaggaaat tgatttttta ctgtcaccct
     7501 aggcaagctt gaaacaaata aatcattgat agtaacactt acgacatcct atttattact
     7561 tcaatttcta atgtctctgc tatttctaag ctacctctgg tatgatctat tcctagtcag
     7621 aatagataac accgttctaa attacgattc atagttactc cttttttgac tcgttactat
     7681 aagactcctc tttacatgcg caaaataatt ttgattcaga ttcatcattt atagttttga
     7741 ttatttttta acagattttt ctgttttctt ctccgaagac tttaaaaatt tttttctaat
     7801 taaatcatcc atataaggac caaatatacc aactactaaa ccaataataa aacttttaaa
     7861 atccataatt accaccaaca tgtcgctgca taggccacac ctccaagtat agctcctccc
     7921 acagcaccag ttgctgcacc ttgccatgtt cttgttttaa ttcctagctg aagacctcgt
     7981 gctgctcctc ctccaacacc tgctttggca aaatctcccc aattgcatcc gccaccttca
     8041 acgcaagcaa gcatatcagt atccataatt tcaaattgtg acatcttttt tgtattcata
     8101 acgaatacct cttttttatt tttaatattt gtcttgttac aaacttgaca agtttagtat
     8161 aacagtatct attaattttt ttcatccaaa tcttgaattg gcatcgaaac gtcttgaatt
     8221 agcttttttg tttcaaaatc atctctattt ttaaaaaaga tgttttctaa tcactttttt
     8281 actattagac ttcctgcaaa actagaatcc tagttcatga ttgataatac cagcaatcaa
     8341 attcattcgt aatccgaagc gtttacgatg atttcgatag gttgttgaaa acattttaaa
     8401 cgtttttact ttggcaaaga tgttctcaac cttgcttctc tccttagata gcgcatggtt
     8461 ataggcttta tcttcagcta ttagcggctt gagtttgctg gatttacgtg gagtttgtgc
     8521 ttgaggatat atcttcatga gcccttgata accactgtca gccaagattt taccagcttg
     8581 tccgatattt ctcatttcta aaaaccatct acttccgttg acttggaact ccgattgcta
     8641 ttttccttga atgattttaa ccacatctcc tacgttttgg agttggtcaa tttcttcatc
     8701 gctgatttcg atactaaatt catcttccag agtcaagata aactccatca agtcaacaga
     8761 atccgcatcc aaatcgtctt tcagactcaa ggattctgtc acgacaaagt cctctccctg
     8821 tcgctcttgg ataatggtca caatacggtc aaaaatttct ttttctgtca tctcttttat
     8881 tctcctgaaa attcacgcgc agtctgggca accacgtctg tttctagcat ggtacggatc
     8941 tgacgaatcg tactataaac agccttggca tcgcttgagc catgagtctt gacaacaggt
     9001 gccttaacac caaacaagac cgctccacca acatctgaat aattgagctg ttttttcaaa
     9061 ccactgaggc tgtccttgag aaggagggca cctagtttcg ctcgaagacc accacctgta
     9121 atagctgtct tgagcaagcc catgattccc atagctgtcc cttcgatgga tttgagcaca
     9181 gcgtttcccg tgaaaccatc tgccacaaca acatctgcaa cgccattcat caaatcacgc
     9241 gcttccacgt ttccgataaa gttcaaactt tcatcagccg ccagtaattc ataagtttcc
     9301 ttacgaagcg ggtcgccctt gctactctct gttccgttgt tgagcaaacc aacgcgtggt
     9361 tgcgcaatgc cacggacatt tttagcatag aaggaaccta gaaccgcata ttgatggagg
     9421 tgctgggctg tattttctgc attggcacca aggtctagca tgtcaaaacc ttttccatca
     9481 acggtaggca aggtagacat gagtccagga cggtcgatat tcttgatacg acccacgatg
     9541 aagaatcctg ctgccaacaa ggcacctgta ttcccagccg aaaggacagc gtctgcttca
     9601 ccatctttga cagccttggc tgccaatacc atactggcat ttttcttatt ccgaatagct
     9661 ctcgtaggtt catcatccga atcaatcttc tcatccgtat ggataatgct gacgcgctct
     9721 gtcgctgtca gatattgctt gattttagct tcatctccgt aaagttgaac ctcgatatct
     9781 gaaaagtcag atagggcttg attgacaccc tcaacgatgg cctgaggtgc gtaatcgccc
     9841 cccatggcat ctactgcgat ttttttcatt tcttttcctc ttttagtaat tgtccccagt
     9901 ctgctaggga atcaataaat ttctttgatt ttaggtgaat cccaacgtac tcttcatata
     9961 gttgatccat aaattggcgt agctcttgct tgattccagg cttgagcgaa atggtctcca
    10021 aagtctcaaa atcaatagct tgaaattgat tgagcagata ggggatattg ggattgagat
    10081 ggcaacgtct ctcatcctca tgataatgct ctggacagag acaggctcca tatttgaaag
    10141 aaaagtcaaa agcctgacca acccgatggc agaagacaca ctcattaaaa ttgaggctga
    10201 ttccaaatcg agtcaaaatt tgaatttcaa aaatattggt caaaacctga taatccaagc
    10261 ctgcttccat caactccaaa gtcttttgca aaaaagcaaa caagggagca tcctgctgat
    10321 tgtcctgcaa actagcatct gcaagagctg ccacataggt cgcataggcc atgacaaaga
    10381 ggtcactatt aatcttggga aaagtcatga cctcatgata gtcttcgatg taactgagtc
    10441 cgtcatcatt gattcgcaag agaaatcgtg ccagcaccaa gggctgaata acaggcgcca
    10501 gcttagactg accagcgtgt ttgacaaaaa acatgcgttt gccaacctgc tctgtaaaaa
    10561 ttttgacgag cttgtcatcc tcacgaaaat tgcgattgta aagcaccaag ccttgactcg
    10621 tgatagactg aatcatgctt ctctcatgta ctcctcaagt cgtttcatgg cttctttgat
    10681 agtctccatg ctggctgcat aagataggcg gacgtagcct tccccgtaac gtccaaaggc
    10741 tgcaccaggg ataaaggcaa cggccttctt ctgagcaaaa tccttcagaa aagcaaagga
    10801 gtcttgattg tagcccgctg gaattttagc aaaaatatag aaggcaccgt ctggtttgat
    10861 aatctcaaaa ccaagagcag tcattttttc gatgatatag tcccgacgtt ggatatattc
    10921 cttcttcatg ggctccgcat cgtttttacc agccgtcaag gcttctaccg cagcatgttg
    10981 cgccatggta tttgcggcag tgaccaagta ctggtgactc ttgattaact gggctgtgaa
    11041 ggtcgcagga gcaaaaatca gccccaaacg ccaacctgtc atggcatgcg atttagacaa
    11101 accattgata ataatagcct ggtctctcaa catcgttcct agagacacat gggcttcgcc
    11161 tgtgtaggtc aattctgagt aaacctcatc acagacaaca aaaatttcgt acttgcgtaa
    11221 aacagctgcc aaggcctcta actgctctcg actgtaggta attcctgtcg gattggctgg
    11281 atagttgaga ataactgcct tgagcttatc accctgctcc aaaatggcct tctccaacat
    11341 ctcaggagtc aagacaaaac cattttcagt cgtatcaatc tcaacaattt ctgccccaac
    11401 taagttaaca atcggttcat agcctggata agcaggagct ggcaaaagta ccttgtctcc
    11461 ctcttccaaa atagccgtca aagtcgcaga taaagcctct gtcgccccaa ttgtaaccaa
    11521 gatttcattt tcaggagcat agtccagttg gtacttttcc ttaacaaagt cactggctgc
    11581 ctgacgtaga gtcagcagac cactcatccc tgtatagtag gattggttct gatcaatcgc
    11641 tcgcttgccc gcctccttga catggtctgg cgttgtaaaa tcaggttccc ccaaggtcaa
    11701 acgcaagacc ccaggaatct ccgaaatagc ctggtcaaac tgacgaatca acgaaacttg
    11761 aattttatct aactgtttat taaagcgctt agttaagtcc atagatacct cctactttca
    11821 aaacgtatct ctattatact acaaaagccc cccgaccgca aaaatacatt agagaatagc
    11881 tttccacttt ctattttact tttcctgttt ataggtctat aatggtaata gattttattt
    11941 ggaggttttt atgtcatttc tatcaaaaaa tggagcaggt atcttggcct gccttctcat
    12001 ttccatccta tcttggtact taggaggatt cttccctgtg attggcgcgc ccgtttttgc
    12061 cattttcata ggcatgctcc tacatccctt tctctcgtcc tataaacaac tggatgctgg
    12121 tttgaccttt agttccaaga agttgctcca atatgccgtt gtcttgcttg gttttggtct
    12181 caatatctcg caggtcttcg cagttggcca atcttcactc cctgtcatcc tgtccactat
    12241 ctcaatagct ctgattattg cctacctctt ccagcgtttc tttgcactgg atacaaaact
    12301 ggctaccttg gttggagtag gttcttctat ctgtgggggt tctgccattg cagcgacagc
    12361 gcctgttatc catgctaagg aaaaggaagt agcccaagcc atttccgtta tctttttctt
    12421 caatgtcttg gctgcgctca tctttccaac cctcggcacc tggcttcatc tatccaatga
    12481 aggcttcgcc ctctttgcag ggactgcggt caacgacact tcctctgtaa cggctgccgc
    12541 cagcgcttgg gacagtcttt accaaagcaa taccctcgag tctgcaacca ttgttaaact
    12601 cacacgtact ttggctatta tccctatcac gctctttctc tcctactggc aaagtcgcca
    12661 acaagaaaac aagcaaagcc tacaactgaa aaaagtcttc ccacttttta tcctttactt
    12721 tatccttgcc tctctcctca ctacactact cacctctcta ggtgtgtcca gtagtttctt
    12781 tacccctctc aaagaactct ctaaattcct tattgtcatg gccatgagtg ctatcggtct
    12841 caaaaccaat ctggtcgcta tggtcaaatc cagtggaaaa tccattcttc ttggagccat
    12901 ctgctggatt gccatcatcc tcaccactct tggtatgcag acccttatcg gcattttcta
    12961 acactcttcg aaaatctctt caaactacgt caacgtcgcc ttgccgta
//
