LOCUS       NZ_CPTT01000012        11084 bp    DNA     linear   CON 13-DEC-2024
DEFINITION  Streptococcus pneumoniae strain 10F/2, whole genome shotgun
            sequence.
ACCESSION   NZ_CPTT01000012
VERSION     NZ_CPTT01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  AUTHORS   Informatics,Pathogen.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2015) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001138385.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 01:30:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 60 of 139
            Pseudo Genes (incomplete)         :: 78 of 139
            Pseudo Genes (internal stop)      :: 32 of 139
            Pseudo Genes (multiple problems)  :: 26 of 139
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:01:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 57583
            Orig. end                         :: 68667
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CPTT01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11084
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11084
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11084
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:9933]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9933
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(333..662)
                     /locus_tag="AEH42_RS06345"
                     /old_locus_tag="ERS011481_01237"
     CDS             complement(333..662)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /locus_tag="AEH42_RS06345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01237"
                     /product="hypothetical protein"
                     /protein_id="WP_000132583.1"
                     /transl_table=11
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGFL
                     AKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLILNE
                     NQRAN"
     misc_feature    801..814
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.71"
                     /tool="antismash"
     gene            939..1277
                     /locus_tag="AEH42_RS06350"
                     /old_locus_tag="ERS011481_01238"
     CDS             939..1277
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /locus_tag="AEH42_RS06350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01238"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_047499348.1"
                     /transl_table=11
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNML
                     QNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYREIR
                     QKWLKEGE"
     gene            1282..2019
                     /locus_tag="AEH42_RS06355"
                     /old_locus_tag="ERS011481_01239"
     CDS             1282..2019
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /locus_tag="AEH42_RS06355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01239"
                     /product="response regulator transcription factor"
                     /protein_id="WP_050116081.1"
                     /transl_table=11
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLA
                     EVHEKGDHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQVS
                     ALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYYLET
                     SPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFP
                     NGGSCLIARYKVREVSEAINNLH"
     gene            2033..3373
                     /locus_tag="AEH42_RS06360"
                     /old_locus_tag="ERS011481_01240"
     CDS             2033..3373
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /locus_tag="AEH42_RS06360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01240"
                     /product="sensor histidine kinase"
                     /protein_id="WP_001017642.1"
                     /transl_table=11
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILLA
                     FVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRGVS
                     YFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQKSLT
                     QINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKEKLYE
                     RLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIKEVYGS
                     VLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEIQVEGMS
                     LLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGIDISEIFSF
                     GASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(3444..3572)
                     /gene="blpC"
                     /locus_tag="AEH42_RS06365"
                     /old_locus_tag="ERS011481_01241"
     CDS             complement(3444..3572)
                     /codon_start=1
                     /gene="blpC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /locus_tag="AEH42_RS06365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01241"
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="WP_000358815.1"
                     /transl_table=11
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(3629..4990)
                     /locus_tag="AEH42_RS06370"
                     /old_locus_tag="ERS011481_01242"
     CDS             complement(3629..4990)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /locus_tag="AEH42_RS06370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01242"
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="WP_050116083.1"
                     /transl_table=11
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKEI
                     TVTSQGEIAPTSVIASIQSTSDNPILANYLVANQVVEKGDLLIKYSETMEESQKTALAT
                     QLQRLEKQKEGLGILKQSLETTTDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTNTEV
                     SNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRYLVAS
                     QGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVLRTQFL
                     QTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRIPTGTEI
                     AQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQTIDQTPT
                     RTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILTHSD"
     gene            complement(5001..>6179)
                     /gene="blpA"
                     /locus_tag="AEH42_RS06375"
                     /old_locus_tag="ERS011481_01243"
                     /pseudo=""
     CDS             complement(5001..>6179)
                     /codon_start=1
                     /gene="blpA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /locus_tag="AEH42_RS06375"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01243"
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /pseudo=""
                     /sec_met_domain="TIGR01193 (E-value: 2.7e-182, bitscore:
                     599.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNI
                     DSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNT
                     LFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDD
                     LSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQD
                     IKNIDKKVLRRHINYLPQQAYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIER
                     MPMGYQTQLSDGAGLSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLIS
                     LTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            complement(6200..7153)
                     /locus_tag="AEH42_RS06380"
                     /old_locus_tag="ERS011481_01244"
     CDS             complement(6200..7153)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /locus_tag="AEH42_RS06380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01244"
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="WP_001155323.1"
                     /transl_table=11
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTIH
                     NEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQKF
                     SPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGKSIE
                     ERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVNQALT
                     LLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENYNRLIRRWLPKG
                     TKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     misc_feature    7124..7139
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 20.67"
                     /tool="antismash"
     gene            complement(7410..7871)
                     /locus_tag="AEH42_RS12355"
                     /old_locus_tag="ERS011481_01245"
     CDS             complement(7410..7871)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="AEH42_RS12355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01245"
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="WP_309543754.1"
                     /transl_table=11
                     /translation="MVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQV
                     MSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALA
                     STILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPF"
     gene            complement(7816..8403)
                     /locus_tag="AEH42_RS12360"
                     /old_locus_tag="ERS011481_01246"
     CDS             complement(7816..8403)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /locus_tag="AEH42_RS12360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01246"
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="WP_000205166.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.8e-43, bitscore:
                     138.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTN
                     KEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQTK
                     KDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPSSDF
                     QTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            8701..8898
                     /gene="blpI"
                     /locus_tag="AEH42_RS06395"
                     /old_locus_tag="ERS011481_01247"
     CDS             8701..8898
                     /codon_start=1
                     /gene="blpI"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /locus_tag="AEH42_RS06395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01247"
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="WP_001093259.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.1e-12,
                     bitscore: 37.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAATG
                     PITGGAATLICVGSGIMSSL"
     gene            9365..9634
                     /gene="blpJ"
                     /locus_tag="AEH42_RS06400"
                     /old_locus_tag="ERS011481_01248"
     CDS             9365..9634
                     /codon_start=1
                     /gene="blpJ"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /locus_tag="AEH42_RS06400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01248"
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="WP_001093248.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 6.3e-20,
                     bitscore: 63.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITGG
                     TGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            9703..9933
                     /gene="blpU"
                     /locus_tag="AEH42_RS06405"
                     /old_locus_tag="ERS011481_01249"
     CDS             9703..9933
                     /codon_start=1
                     /gene="blpU"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /locus_tag="AEH42_RS06405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01249"
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="WP_000379967.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.4e-18,
                     bitscore: 56.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQL
                     GIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            9936..10055
                     /locus_tag="AEH42_RS06410"
     CDS             9936..10055
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /locus_tag="AEH42_RS06410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="WP_000346298.1"
                     /transl_table=11
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     misc_feature    complement(10191..10204)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.08"
                     /tool="antismash"
     gene            10354..10518
                     /locus_tag="AEH42_RS11045"
                     /old_locus_tag="ERS011481_01250"
     CDS             10354..10518
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727116.1"
                     /locus_tag="AEH42_RS11045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01250"
                     /product="hypothetical protein"
                     /protein_id="WP_000727118.1"
                     /transl_table=11
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYFA
                     INKKKGEKK"
     gene            10515..10919
                     /locus_tag="AEH42_RS06415"
                     /old_locus_tag="ERS011481_01251"
     CDS             10515..10919
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /locus_tag="AEH42_RS06415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_01251"
                     /product="hypothetical protein"
                     /protein_id="WP_000846944.1"
                     /transl_table=11
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQFL
                     LVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGE
                     SYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
ORIGIN
        1 caggaggtag ttcgaggatt gaccagtttt gttttacttg tggaattagt tgttgggttg
       61 attaccttcc aagaaaaact agcccttcta gccttactag gagctggttt ggttttacta
      121 gtcttgtatt tgccttatca ggtaaaacgt cagatgcagg actaacattg ctgatacgac
      181 actaaaaaag aagttgagtt cagtctgtct caacttcttt tttgttacta caggataatg
      241 gttggtccgt agagacttat actcttcgaa aatctcttca aaccacgtca gcgtcgtctt
      301 accgtactca agtacagctt gcggctagct tcctagtttg ctctttgatt ttcattgagt
      361 attaacttgg tcttgacttg gtcaaagtgg aagcggtcat aggcccgcca agcggcgcga
      421 gttggagcat ctggatcaag agcgctgagt cccatgagaa gactggaagt ctggtaaaat
      481 ttttccaatt caatcaagaa tcgattatcc actgtttcag ccttggctag aaaaccaaga
      541 atagagttta attgctcctg aaagcggacg tcgtcagcgg ttgcctgttt gcatgcttga
      601 taggctttgt ttaagtcagt aatcaaagtc tgagctcttt tgatagggtc tgtatctgtc
      661 atgggaatgc ctcctctaat ctgggtgcca gtcttgattc tagcaactgt gttttgatac
      721 tgtcagtcta tcacttttat ctcctttttc gcctttaaat ctttaattgt cattgaaatg
      781 tcttgaattg cgctgagtga attttatgat aaaatagttg taagctcatc atgatgttgt
      841 agaaaaataa tccttttagg agctttcaaa gactgtttag gattgggtgg gcttgggcta
      901 gaccttttct gttattcttt tcttaggagg agaatccaat gaaacatatg attattcaga
      961 cgcagaaaac agtctataaa gtaaacgtcg acgatatcta ctatatccaa acacatccaa
     1021 ctaaagccca taccgtacag attgttacag aagaagctag ttttaatatg cttcaaaatt
     1081 taagtaatct tgagaaccaa tgtggggaaa ccttgatgag atgtcatcga aattgtttgg
     1141 ttaatcttga taaattaaaa tcgattgatt ttcaagaaag aatccttttt ctcggagaag
     1201 aaggtcaata cgctgtcaag tatgccagac gtcgctatag agaaattcgt caaaaatggt
     1261 tgaaagaggg agagtaagaa gatgagaata tttgttttag aggatgattt ttcccaacag
     1321 actagaattg aaacgacgat tgagaaactt ttgaaagcac atcatatcat tcctagctct
     1381 tttgaggtat ttggcaagcc ggaccaactg ctggctgaag tgcatgagaa gggggaccat
     1441 cagctattct ttttggatat tgagattcga aatgaagaga tgaagggact ggaagtggct
     1501 agaaagattc gggatcggga tccttatgcc ctgattgtct ttgtgacgac tcactcggag
     1561 tttatgcccc tgtcttttcg ctaccaagtg tctgctttgg actacattga taaggccttg
     1621 tcagcagagg agtttgaatc tcggatcgag acagccctcc tctatgccaa tagtcaagat
     1681 agtaaaagtc tggcggaaga ttgcttttac tttaaatcaa aatttgccca atttcagtat
     1741 ccttttaaag aggtttacta tctcgaaacg tcgcccagag cccatcgtgt tattctctat
     1801 accaagacag acaggctgga atttacagcg agtttagagg aggttttcaa gcaggagccc
     1861 cgtctcttgc agtgccaccg ctcttttctc atcaatcctg caaatgtggt gcatttggat
     1921 aagaaagaaa aactgctttt ctttcccaat ggtggaagtt gtctaatcgc ccgttataag
     1981 gtcagggaag tgtctgaggc tattaataac ttacactgag ctaggagaat ttatgaacat
     2041 tgcttggata ttgttgtata cacttgttac taatggacta gaaattgtca tcttctttaa
     2101 ggtggatgga attgatctta ctttcgagag gatttttaag gcctttcttt ttaagatact
     2161 gttggccttt gtttttgtga tgattagcta tatagtagga aatgtttacc tatcttattt
     2221 tatggaaccc ttgtacggca taggcttatc tttcttatta ttgagagggc ttcctaaaaa
     2281 actccttttc ttttatggtc tctttccaat gatattggtg aatctctttt atagaggagt
     2341 ctcctatttt gtgcttccat ttttgggaca agggcaagta tatgatggct actcatttac
     2401 tgggttatgt ataataattt tcaatttctt catttctcta gcttttttga aatggttgga
     2461 ctacgatttt actagcttga gaaaggagat tctcgataaa gcctttcaaa agtccctgac
     2521 tcagattaac tggataatgg gtggctacta tctagtcatg gaaagtctgt ctttttttga
     2581 atatgaacaa agtattcaat caaagactgt tcgccatctc atcctagtct tttacctact
     2641 cttttttatg ggggttatca agaaattgga tacctatttg aaggaaaaac tctatgagag
     2701 attggaacaa gagcaggccc tgcgctatag agatatggaa cgctatagtc ggcatataga
     2761 ggagctttac aaggaagtac ggagttttcg ccatgattat accaacctct tgactagctt
     2821 acgtctgggc attgaagagg aggatatgga gcagataaaa gaggtctatg gctccgtctt
     2881 aaaggattcc agtcagaaat tgcagaacaa taaatatgac ctgggcagat tggtaaatat
     2941 tcgtgataaa gccctcaaaa gtcttctagc agggaaattt ttaaaagcca gagataagaa
     3001 cattgtcttt aatgtcgaag ttcctgagga gattcaggtc gaggggatga gtctacttga
     3061 ttttctaacc attgtgtcta tcctttgtga caatgctatt gaagccagtg tggaagctag
     3121 tcaacctcat gtttcaatcg cctttttaaa aaatggagca caggagacct ttatcatcga
     3181 aaactccatc aaagaagagg gcatcgatat ttctgaaatc ttctcctttg gagccagttc
     3241 taaaggggag gagagaggag ttggtctcta taccgtcatg aagattgtgg aaagccatcc
     3301 taataccagt ctaaatacca cctgtcaaaa tcaagtcttt cgtcaggtac ttactgtgat
     3361 acatacagaa tgatgaaaaa taagaccgag agtacttgtt tctcggtctt atttttttat
     3421 agttgtattg gatgatgaag ttcttatgtg atgtaatgag catatctatt aatgttatat
     3481 aataaatctt cccacaatcc tccacctgta atttggttga gttcggtagt tgttagttct
     3541 tgaaatgaag ttaggttttg tttcttatcc atgttatgat tctccttttt gataagataa
     3601 taaatagtta tagagtgtta tctgaaaatt aatcagaatg tgttaaaatt ttatctttga
     3661 aataatcaaa atatgttttc tttgtagtta cactagtgac gcgaccttgt aagccatatt
     3721 ggatgagttt actatcctcg ttagatagtt ttgcaagagc ggttaattta aagagatttc
     3781 cttgctctgt tctggtagga gtttgatcaa ttgtctgaag ttggccgatg atggtggtgc
     3841 cgtgatttcc aatcttctcc agttttaatc ttacagtttg tcctttatct agtagaggta
     3901 gatagtcaga agatacgtag taagtgatta gtacttctct tgtatctgtg atgacaggga
     3961 atatttgagc aatttctgta ccagttggaa ttctattttt accttcaaat tcgctgttca
     4021 gatgaacgat acctttactt ggggaggtta aggtattgtt ttccaaacgc tgtgtggctt
     4081 gatctagttg tacttttaat tctgttaatt gattctccac agttagttgt tgctgtgagg
     4141 ctgtctgtaa aaactgagtg cggagtactt caattttggt tgctaaactg ttatcataag
     4201 ttgctacact tccgatacca gcttgctgaa ttttgaggct tgcgatagat gattcaagac
     4261 ctgcaatact ttgattaatt tgagataaaa atggctcctc tgcagttcct tgtgtttgtc
     4321 cttgtgaggc tacaagataa cgattcaaaa ttgactggtg cggattgcca gttggtaagc
     4381 gtgctctgtt atttatgata gcatctctca actcttgata ttctccaatt tgttgttgaa
     4441 cttttgtaat ttcttgttca atagctgatg aactgctatt ggaaagatta gcttgatttg
     4501 aaacttcggt gttagtcttt gtgataccca gttcaatatc atgggattgt ttagtaaaat
     4561 tcataaaggt attatggtag ccaaattcat cctcgccaga aaaaagatca gtcgttgttt
     4621 ctaagctttg tttcaaaatt ccaagtcctt ctttttgctt ctcaagtctt tgtaattgag
     4681 ttgctaaggc agttttctga ctttcttcca ttgtttcaga gtatttgatg agtaagtcac
     4741 ctttctcaac tacttgattt gccactaaat aattagcaag gataggatta tcactggtcg
     4801 actgaataga tgcaatgaca cttgtagggg cgatttctcc ttgggaagta acagtaattt
     4861 cttttgtggc aacaagggag aaaatcaaga tgaaagtaaa cagtaatgaa agaggtataa
     4921 ttaacactgt cgcatagtta tggtaacgtc tctgataaaa ctcgacgctt ctaaaaagat
     4981 taggattcat gacattctcc ttatttattg aatagatgat ggtagaagcc ttgcgcctgc
     5041 attaactctt ggtgactacc aacttcaatg attttcccct ggtcaagaac aatgacacgg
     5101 ttggttcgtt cggctatact gagacgatgg gctacaaaga gaatggtttt atcagttagg
     5161 gatataagat tatctataac ctttttctca gtcaagacat caagaccgct agtagcttca
     5221 tctagtatta aaacaggagc tttagttaaa agagcacgag cgagagcgat tcgttgcttt
     5281 tgtcctcctg atagaccagc tccatcagag agctgagttt gatagcccat aggcattctt
     5341 tcaatgtctt gacgaatttc agctaattca caagctttta gaatatcttc ttggctaatc
     5401 atatgattac cgcccaaggt taagttttcc aaaatagagc cattaaagat ataggcttgt
     5461 tggggtaggt aattaatatg acggcgcaag acttttttat caatgttttt aatatcctga
     5521 tgattgatgg aaatatgccc tttgtagggt tcaaagaaat tgacaatcat tttggctaaa
     5581 gttgttttac cagaaccact aactccaact aggctaacct tatctccttg tttaatcgtg
     5641 agattaatat ctgttaaggt atctcgtcca aaaccatact tataagaaag gtcatcaaat
     5701 tcaatatcgc ccatcaaaaa atgtgaatga acagggtttt cttgaacttg aaattcagat
     5761 tcgactagat agacttcgtt caaacggtta ttagcgacct tcgcagattg gagtttggtt
     5821 tggaggttga taatattttc cataggagtt gtaaagtaag aaaaaagtgt gttaaaggta
     5881 atcagctgac cgatagaaat tttactcgac atgactaatt gagcgccaaa ccataggata
     5941 aggatattca gaactaattt tgttccctgc tttaaactcg tttgtaaaat agaatattta
     6001 ctgagcttaa aggatttttc caaataatct acaaattcgc tgtctatatt ttgatagcga
     6061 ttttcttcac tcgtgagcga ctttatagtt tcaatcccgt tgatatcttc gataatggca
     6121 gagctaacca tagaattact ttgcatgaca tcatggttca ttttttcaaa aggtttcata
     6181 cccaaatttc aagttgaagt tagccaccca aaagaaattc acttggcgac ttgtagtcca
     6241 agcatttttt agggtagttg ttaatccaat tttcgataaa agctacttct ttcggagtcg
     6301 ttttcttggt tcctttaggt aaccatctcc gaattaatcg attataattt tcatttgaac
     6361 ctctctccca tgaagagtaa gcatgtgcgt agtagatatg ttcctcagga aatacctcag
     6421 acaatcgttt gaactccgaa ccattatctg cagtaatgga cagaatacga tgctccccta
     6481 atagtaacgt aagcgcctga ttgacagatt cagcagtttt atttggaatt aaccttataa
     6541 tttggtgtct gctccgccgg tcggttaaga ctaacaggca ataatttttt atcttagtca
     6601 gtaggacggt atcaatttca taatgaccat tttccaagcg aagattaata acgtcaggac
     6661 gttcttcgat agatttacct gccggcttaa agttcggact agcttgcttc ttgacacctt
     6721 tcctttttct gggataaagc atgtcggcct tcgtcaatcc taaatgacca ttatgaaacc
     6781 agtagtagat ggttgaaata ccaactttca cttgcttctt gttaaccatc atttcaggcg
     6841 aaaatttttg cttatgatag tgtaagatct tctctctgat ttcctttgtt aaaattaact
     6901 ttttcaccga ccgttttcga ttgaattggt aaacagtttg tgcgtaatcg gcagaataga
     6961 cctttttgta tagccctttt ctcacttgtt gtaaagttgt acctcttttg acttcattat
     7021 gaatcgtttg aggcgccttt cctaacaagc ctgcaatttc acgattggac ttattttcat
     7081 tcttccaccg ctcaatcaag cgacggttat ctattgtcaa atgtttccct tttggggtat
     7141 aatgttcttg catctctgtg cctttccttg tgtttgtggt gaacaacaag tatagcacag
     7201 aggtgttttc ttatacctta aatcacattt catttgacaa caggaaccct tgaacctgtt
     7261 ttttcagcta aaccaaggct atgattagcc ttggccacct agcctaacag tttcaaacct
     7321 gttatcaaat gaaatcatca acttactcaa acatagtgaa acatctaatt cttgactaag
     7381 gtaaggtggc taacttcatt atagaacttt caaaaaggtt tcataaaaga aaagatgatg
     7441 aacatgtata taggaatgga aagaagagaa aggaggaaga gattagggtt ttgtgccagc
     7501 aagactcctc ctacaagaat cagaatagaa acatccagaa aaagagaaag aatggtagaa
     7561 gccaaggcat ctataataga gttagcatct gtgaaccgtg aaatgatttc tcctgtacga
     7621 cgtgtcgcaa agaaagacat gggaagttca aaaatatggc gaatatagga taaaatcaca
     7681 tcaatgctta atctctggct cagaacggtt aggagataat ctctggaaaa gctcatgact
     7741 tgttggagga tataggtgat aaccagacca actgagatga ttcctaaagt tgatttcatc
     7801 tgatttggga tgtattcatc caagattcct tggagataat aagaaccacc gatattgata
     7861 atagtgacca ataagcttga gagaacaatg taagcaatga gagatttttg tttgaaaatc
     7921 agaggaagga agcttgctta gtagaccatt ctttttatct ttatggggtt gatagctggg
     7981 tttggtagct agaaaaatag ctactccagt ccattcatag aaaaagcgtt cttttgacat
     8041 tttagtgatt tttacagaag ggtcaggatc accaataatc agatagtctt tctttgtttg
     8101 atagacaaca tagtaatgtt ggagttttcc ttctttgtta acgtgaacga taaatggata
     8161 ggggacatca ctcatgtcaa agagcgtttt atctgcttga acaggtcttg tttcaaagcc
     8221 catttcatca gcggctttta caatgccaag agcagtcgtc ccttctttat tggtctttgc
     8281 aagttctctc aagtgagcta gagaaaaatc tgaaccatag aatttagcaa tcgaggctaa
     8341 ggcagcgaca ccacagtctc tcgcatctat ttgaggaaca aatgtacgtt tataagaagt
     8401 cattggcaat tcctttcata tagtggatag gtctattatg tcataaaact aagttcatat
     8461 tttatgaaat cttgaatagt cattaaaact tcctgaatgg taaaaaagtg attagaaatt
     8521 atttttttta aacatttaga ggtggcttga aatagaggtg gcttgaaata aaaaagctaa
     8581 ttcaagacgt ttcgatgaca attcaagatc tggatgaaaa attttaaaaa acgatgatat
     8641 actaaactta tcaaagttac aacaagacaa aaataaaaaa agaaaaaagg agtatttgtc
     8701 atgaatacaa aaatgatgga acaattttct gttatggata atgaagaact cgaaatagtt
     8761 agtggaggaa gaggcaattt aggatctgca atcggtggtt gtattggagc agtactatta
     8821 gctgctgcga ctggtccgat aactggggga gcagcaacac ttatttgtgt aggttcagga
     8881 attatgtcct ctttgtaaga ttatgattct taaatatagt attattatcg ctattaattt
     8941 actgtcttat ttacttactt acaaaatatc aaagttatct aagaatgatg agaataagat
     9001 agttagcaaa attttaatta tattatcaat cgtttatgta atcgttgatg ctttacttag
     9061 ttgatggatt ggtaggaata aaaaacttaa ctataaacta ttatttacta atattttttg
     9121 ctttctgcaa gttaataaat agtatagtaa aactttttat tgcaaggaga ataacgaaat
     9181 taagatattt tagatactca agattattga aatcttagac taaaaaatag gtactgctac
     9241 ctttaagaag atagtagacg tatatacttt tttaagaaaa tcaaaaagat actataaaaa
     9301 atctatttgt ttattgaatt taagactttg gtaacaaatt gaaaataaaa aggaggtatt
     9361 catcatgaat acaaaaatgt tgtcacagtt agaggttatg gatactgaaa tgcttgcgaa
     9421 agttgaaggg gggtatagct ccactgattg tcaaaatgca ctgattacag gagtcactac
     9481 gggaattata actggtggaa ctggagcagg tttggccact ttaggagtag ctggacttgc
     9541 tggtgcattt gttggagcac acattggtgc aattgggggt ggattaacat gcttaggagg
     9601 tatggttggt gataaattgg gactaagttg gtaagactta tagtaaaatt atgaggattc
     9661 tattctgatt tattttagtt ttttaaaaaa ggagtatttg tcatggatac aaaaatgatg
     9721 tcacaatttt ctgttatgga tactgaaatg cttgcttgcg ttgaaggtgg cggatgcaat
     9781 tggggagatt ttgccaaagc aggtgttgga ggaggagcag caagaggtct tcaactaggc
     9841 attaaaacag gaacatggca aggtgcagca actggtgctg cgggtggagc tatacttgga
     9901 ggtgtagcct atgcagcaac atgttggtgg taattatgga ttttaaaagt tttattattg
     9961 gtttagtagt tggtatattt ggtccttata tggataattt aattagaaaa atattttcaa
    10021 aatttcccaa aaaggataca gatagtaccc cctaaaaaat aaatttctcc cctgtatttg
    10081 ctagcttaat ttacagggga gtttctttaa tattgtttcg cctgtcaaaa tgatatgtga
    10141 tagcaggatg aaaagtctgc aaacaagttg gtatcaatac aatataaaga ggaaagtatg
    10201 tttttaatgc ttacttttta aattttttaa caattcaaga ggttttgatg accatttatg
    10261 atttgagtga tccaaggtca aaataagtgc tatactagca gtgtaaatgt tcttgctcaa
    10321 ctaagataaa tcgcacattt aggaggaaat cttatgaaga aaaaaatact gattattttc
    10381 gttctgtatc taatcatgtc catctttcta tatccgctta gggagagtgc ttggtatcag
    10441 ctattttata ccatagccta tgtgattgca gttatgatct attttgctat caataaaaag
    10501 aaaggagaaa agaaatgaaa acttttcttg ctaaaaaacg gaacatcttc cttgcgagat
    10561 tgttcttagg tcagttgccc ttgcttgttt ctacttatct atttctatct cgtcagtttt
    10621 taaatttttc cgtagttttc caatttcttt tagtagttat taacttggct tctattttgg
    10681 ttactgttta tctcactagg gaaatgagga taagagagtt tgaagatgat gatttggtta
    10741 gtcctagaac caatcaactt atgtttatcg gcttgacagg ttttatgtct attatttgtt
    10801 tgtatagagg tatcacagca ggagaatctt atcaacaact aatcgcttat attggcgctg
    10861 ttctctgctt aatcatcatg cttctgctca tgtggggctt gaagtattat aaaaagtaga
    10921 gcttaatgaa gtataaaaga aaagggtaag tgtttttgca atacttaccc ttttataata
    10981 gattccctgc gaaacaaaat atggtatagt atagtatatt gaaactagaa tagtacgcct
    11041 ctacttctaa aacattgtta gaaatcgatt tgactgtcct gatc
//
