LOCUS       NZ_CPTT01000004        21939 bp    DNA     linear   CON 13-DEC-2024
DEFINITION  Streptococcus pneumoniae strain 10F/2, whole genome shotgun
            sequence.
ACCESSION   NZ_CPTT01000004
VERSION     NZ_CPTT01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  AUTHORS   Informatics,Pathogen.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2015) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001138385.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 01:30:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,083
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 60 of 139
            Pseudo Genes (incomplete)         :: 78 of 139
            Pseudo Genes (internal stop)      :: 32 of 139
            Pseudo Genes (multiple problems)  :: 26 of 139
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:01:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 96067
            Orig. end                         :: 118006
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CPTT01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21939
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..21939
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21939
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:21173](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21173)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(144..935)
                     /locus_tag="AEH42_RS02980"
                     /old_locus_tag="ERS011481_00573"
     CDS             complement(144..935)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /locus_tag="AEH42_RS02980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00573"
                     /product="hypothetical protein"
                     /protein_id="WP_000701263.1"
                     /transl_table=11
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDLA
                     KFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIGRE
                     VSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQRLLD
                     GEITSYLFFTCVLLIGIFINAVYFFKIVDYLGNVTRSAITYLMFLWLGSMLLYSALPYY
                     MVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(1115..1450)
                     /locus_tag="AEH42_RS02985"
                     /old_locus_tag="ERS011481_00574"
     CDS             complement(1115..1450)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /locus_tag="AEH42_RS02985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00574"
                     /product="hypothetical protein"
                     /protein_id="WP_000400505.1"
                     /transl_table=11
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLYA
                     LFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMLDLRRELG
                     KSKGGRH"
     gene            complement(1590..1925)
                     /locus_tag="AEH42_RS02990"
                     /old_locus_tag="ERS011481_00575"
     CDS             complement(1590..1925)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /locus_tag="AEH42_RS02990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00575"
                     /product="hypothetical protein"
                     /protein_id="WP_000400493.1"
                     /transl_table=11
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFYS
                     LFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQELG
                     KSKGGRH"
     misc_feature    complement(1950..1961)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.14"
                     /tool="antismash"
     gene            complement(2016..3326)
                     /gene="der"
                     /locus_tag="AEH42_RS02995"
                     /old_locus_tag="ERS011481_00576"
     CDS             complement(2016..3326)
                     /EC_number="3.6.5.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="der"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /locus_tag="AEH42_RS02995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00576"
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="WP_001207696.1"
                     /transl_table=11
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYAT
                     GEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVA
                     RKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENL
                     PNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDG
                     QEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGF
                     AHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLP
                     EMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFV
                     NEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(3340..4053)
                     /locus_tag="AEH42_RS03000"
                     /old_locus_tag="ERS011481_00577"
     CDS             complement(3340..4053)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /locus_tag="AEH42_RS03000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00577"
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="WP_050091123.1"
                     /sec_met_domain="PF00881 (E-value: 3.9e-24, bitscore: 78.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETIKLMKAHTSVRRFKEQDLPQEDLTEILTAAQMASSWKNFQS
                     YSVIVVRSQEKKDTLYELVPQEAIRQSAVFLLFVGDLNRAEKGAQLHTDSFQPQGVEGL
                     LISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYPVFGMALGVP
                     NQTHDVKPRLPLDNVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQFGQA
                     EPSSTRKNLEQKKLL"
     gene            complement(4050..4946)
                     /gene="dnaI"
                     /locus_tag="AEH42_RS03005"
                     /old_locus_tag="ERS011481_00578"
     CDS             complement(4050..4946)
                     /codon_start=1
                     /gene="dnaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /locus_tag="AEH42_RS03005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00578"
                     /product="primosomal protein DnaI"
                     /protein_id="WP_050091124.1"
                     /transl_table=11
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFIQQESLTPKELN
                     RSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAAIK
                     NRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGVGKS
                     FMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILDDIGA
                     EQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEARRVME
                     RIRYLAEETRLEGVNRR"
     gene            complement(4947..6116)
                     /locus_tag="AEH42_RS03010"
                     /old_locus_tag="ERS011481_00579"
     CDS             complement(4947..6116)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /locus_tag="AEH42_RS03010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00579"
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="WP_050119189.1"
                     /transl_table=11
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISFW
                     DNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQDFL
                     EHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKKVAN
                     DFDLEHFRQLMVRDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVISTKR
                     MREKIAQKPVSSDFSLKEATIIKEAKSKTTLQFLSEIKQTRKGTITQTERDLLQQMAGL
                     GLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRERGQKTKT
                     QKQNQTAPAKTNIPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(6117..6590)
                     /gene="nrdR"
                     /locus_tag="AEH42_RS03015"
                     /old_locus_tag="ERS011481_00580"
     CDS             complement(6117..6590)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /locus_tag="AEH42_RS03015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00580"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_001203672.1"
                     /transl_table=11
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVE
                     ERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQ
                     SEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            6730..7095
                     /locus_tag="AEH42_RS03020"
                     /old_locus_tag="ERS011481_00581"
     CDS             6730..7095
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /locus_tag="AEH42_RS03020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00581"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_000119153.1"
                     /transl_table=11
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEAG
                     VNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTHFG
                     YEKEELPGVVSDYIKGV"
     gene            7100..7795
                     /locus_tag="AEH42_RS03025"
                     /old_locus_tag="ERS011481_00582"
     CDS             7100..7795
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /locus_tag="AEH42_RS03025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00582"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000054201.1"
                     /transl_table=11
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTTL
                     IKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYKDF
                     NLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPAARA
                     YILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESGESID
                     QLFRQEFKA"
     gene            7812..8579
                     /locus_tag="AEH42_RS03030"
                     /old_locus_tag="ERS011481_00583"
     CDS             7812..8579
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /locus_tag="AEH42_RS03030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00583"
                     /product="hypothetical protein"
                     /protein_id="WP_050119192.1"
                     /transl_table=11
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQE
                     SQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITAKL
                     IGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLNTIS
                     GILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGLNGHF
                     YMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     misc_feature    7838..7853
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            complement(8932..10131)
                     /locus_tag="AEH42_RS03035"
                     /old_locus_tag="ERS011481_00584"
     CDS             complement(8932..10131)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /locus_tag="AEH42_RS03035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00584"
                     /product="ABC transporter permease"
                     /protein_id="WP_001245353.1"
                     /transl_table=11
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGSS
                     MAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSVLK
                     AVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEAKEN
                     KKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYARMMA
                     LFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISLFMYVV
                     LAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPFISTFFM
                     PFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTFKRALSYK
                     "
     gene            complement(10128..11021)
                     /locus_tag="AEH42_RS03040"
                     /old_locus_tag="ERS011481_00585"
     CDS             complement(10128..11021)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /locus_tag="AEH42_RS03040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00585"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000895292.1"
                     /transl_table=11
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIFH
                     SILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDAKE
                     VKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLDPVN
                     TELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQYGKT
                     RLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIATFDQQ
                     APTIDEIFKLESGVEV"
     misc_feature    11715..11731
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.07"
                     /tool="antismash"
     gene            <11726..11920
                     /locus_tag="AEH42_RS03050"
                     /pseudo=""
     CDS             <11726..11920
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /locus_tag="AEH42_RS03050"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS30 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GSNENHNRLIHRWLPKPKGTKKTTTKEVAFIEKWINNYPKKCLNY
                     KSPREDFWMTNLNLKFSNN"
     gene            12335..12952
                     /locus_tag="AEH42_RS03055"
                     /old_locus_tag="ERS011481_00586"
     CDS             12335..12952
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /locus_tag="AEH42_RS03055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00586"
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="WP_000076185.1"
                     /transl_table=11
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQSK
                     ETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGIVI
                     GCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADFLCM
                     LAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(12995..13882)
                     /gene="scrK"
                     /locus_tag="AEH42_RS03060"
                     /old_locus_tag="ERS011481_00587"
     CDS             complement(12995..13882)
                     /EC_number="2.7.1.4"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008865 - fructokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scrK"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /locus_tag="AEH42_RS03060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00587"
                     /product="fructokinase ScrK"
                     /protein_id="WP_000164302.1"
                     /transl_table=11
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKTI
                     EFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPMYF
                     TTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHYYVA
                     RHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYIAQAA
                     VNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAVAGNGS
                     ATLGNFVLAKEVSK"
     gene            complement(14031..15914)
                     /locus_tag="AEH42_RS03065"
                     /old_locus_tag="ERS011481_00588"
     CDS             complement(14031..15914)
                     /EC_number="2.7.1.211"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /locus_tag="AEH42_RS03065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00588"
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="WP_050119199.1"
                     /transl_table=11
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVI
                     ENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQRA
                     IRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVV
                     WSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPA
                     FIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATK
                     AILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGA
                     ATVAVGVKTQNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLA
                     SILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAA
                     AKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGV
                     VYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKVAQGNKVKAGD
                     VLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGNAVIEVKI"
     misc_feature    complement(16087..16101)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.76"
                     /tool="antismash"
     misc_feature    16199..16214
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.4"
                     /tool="antismash"
     gene            16291..17745
                     /locus_tag="AEH42_RS03075"
                     /old_locus_tag="ERS011481_00589"
     CDS             16291..17745
                     /EC_number="3.2.1.26"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /locus_tag="AEH42_RS03075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00589"
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="WP_000455313.1"
                     /transl_table=11
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGLL
                     NDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDSHG
                     AYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPADSTD
                     HFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRTAYMM
                     ECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQLQNMD
                     YGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDDKLYQYP
                     VAAIKDLRTSEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSINFDLVNGQ
                     VTVDRSQAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVFSGRVFPHA
                     DQNGILIKSGNPTGTYYELDYGRKTN"
     gene            17726..18691
                     /locus_tag="AEH42_RS03080"
                     /old_locus_tag="ERS011481_00590"
     CDS             17726..18691
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /locus_tag="AEH42_RS03080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00590"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_000226001.1"
                     /transl_table=11
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMRELG
                     YKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDSEK
                     EREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAGGVL
                     AAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKEMEIK
                     NILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQLATIK
                     QPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(18727..20001)
                     /locus_tag="AEH42_RS03085"
                     /old_locus_tag="ERS011481_00591"
     CDS             complement(18727..20001)
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /locus_tag="AEH42_RS03085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00591"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_000704382.1"
                     /transl_table=11
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTVA
                     DQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFTAQ
                     VHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVEQIK
                     GEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMAILSNYATDSLVTAS
                     CRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIATGNDWR
                     AIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPRVALSHD
                     LLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGASESEVAP
                     LVERLISDKTFNLETAQRYLENLRS"
     gene            complement(20001..21173)
                     /locus_tag="AEH42_RS03090"
                     /old_locus_tag="ERS011481_00592"
     CDS             complement(20001..21173)
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /locus_tag="AEH42_RS03090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00592"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_000151960.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 3e-09, bitscore:
                     29.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSIA
                     PLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFARS
                     FEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAMLIT
                     QNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQKRYQL
                     TLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGNIYTGS
                     LFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLNKLNQRT
                     ALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(21304..21552)
                     /locus_tag="AEH42_RS03095"
                     /old_locus_tag="ERS011481_00593"
     CDS             complement(21304..21552)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /locus_tag="AEH42_RS03095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS011481_00593"
                     /product="hypothetical protein"
                     /protein_id="WP_001858369.1"
                     /transl_table=11
                     /translation="MVSSWGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFYQ
                     KFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     CDS             complement(<21623..21935)
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="AEH42_RS03100"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ERS011481_00594"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKP
                     LIAEDKAYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELG
                     F"
     gene            complement(<21623..>21939)
                     /locus_tag="AEH42_RS03100"
                     /old_locus_tag="ERS011481_00594"
                     /pseudo=""
ORIGIN
        1 ttgaaatcaa ttctctcttg aaaaagataa cagcatcctg cttttgaacc gctgttgaca
       61 atagatggtt tatcaaaatc atcatcagaa ctatacgaag tagtaaaaca atctttctct
      121 ttagcaaaat attgttaaaa ttcttaaaca ttatcttcat atttttcaag caccatgtaa
      181 gggacaatat aaaggatata aggagtaaag agtttcatca aacttacatc cccatagcta
      241 gcttgcatca aactcgtcat aggaaccata tagtaaggca aggcactata gagcagcata
      301 gaaccaagcc aaagaaacat caaataggtg attgccgaac gagtcacatt tcctaaataa
      361 tcaactattt taaaaaaata gactgcattg atgaaaatac cgattagtag gacacaagta
      421 aagaacaaat agcttgttat ctctccatct aggagccttt gtaaactact cccatcagaa
      481 aatagagaat tccatccaag aggagaaaaa gtcccaaaga aatgagttaa aattgcaatt
      541 atcagcacag tcactaaata tatcaaacaa gggatacttg caacttgcaa agtcaacttt
      601 ctttttaacc cttgataact cacttctctt ccaatactca atcgtaaaac tttatttttc
      661 agctcaatat attgaaaacc tagcaaaaca atgatgattg gaataataaa tgattgataa
      721 aaacctagat tgaactggag aatacgaaaa tctaatgctg attttaataa gtcattttta
      781 attgcttgtc catcgaattt agctagatcg ggcgcatgaa tatcaaaaaa gaaataagtc
      841 atcaaaacat cacgataaac caaagcaaga aaaagcaaag taagcaagac ataaacaaat
      901 ttatgccttg caaaagttaa gagaggaatc ttcataagcc acctcctaca aatagaaagt
      961 aatataatac tcaatgaaaa tcaaagagca aactaggaag ctagcgcagg ttgctcaaag
     1021 cactgttttg aggttgtaga tgactgacga agtcagtaac ctacaatcca aggcgacgtt
     1081 gacgtggttt gaagagattt tcgaagagta taaatcaatg ccttccgcct ttagacttcc
     1141 ctagttcccg tctcaagtca agcatttttt tgaaaaagac ataggctaac cagtcactag
     1201 caaaagcgat aagtagtaat aatagccaaa taccccataa cttgatatct gtcaaatttc
     1261 tcaagacgat attgaaaaac agaactgaaa aaactgtcca agcaaggcta aaaagagcat
     1321 agagggtgat gtaaatccag taaaaatagt aaaaaattgg gaaaaattta ctttctctat
     1381 tatccttgtc aatccagctg aaaaagtaaa aacagggtaa taagattatc attttaaaca
     1441 agtgttccat cacaagcctc cttttttaaa ttgttttctt tagtttcgtt ctattaaatg
     1501 ttattaccaa tataaacctt ggaatagcgt gtaataaatg attttagagg taccataagc
     1561 cacctcctac aaatagaaac cgatataaat caatgccttc cacccttaga cttccctagt
     1621 tcctgtctca agcgaaacat ttctttgaaa caggaataag ttaaccaatt cataccaata
     1681 gctagcagaa taaaaagaaa ccaaatgccc cataacttga tatctgtcac atttctcaag
     1741 acggtattga aaaacagaac tgaaacaact gtccaagcaa ggctaaaaag agaatagaag
     1801 gggatgtaaa accagtaaaa ataataaaaa attggaaaaa acttactatt tctgttggcc
     1861 ttctcaatcc agttatcaaa ataaaagtac ggtgctaaaa gtaagaattt aaacaaatgt
     1921 tccatcaccg acatcaccct ccttcttttg atagcgtttt ctattatttt attatatcaa
     1981 aaaaatccgg aactgtcatt ccagattcta cttttttatt tgcgttttct tgcgatgaga
     2041 tgaatcggtg ttccctcaaa aacaaaggcc ttgcggattt gattttccaa gaaacgcagg
     2101 taagaaaagt gcatgagttc ttcttcattg acaaagatga caaaggttgg tggtttggtt
     2161 gccacttggg tcgcatagaa aatcttgaga cgttttcctt tgtctgtcgg tgttgggttg
     2221 atggcaatgg catccatgat gacatcgttc aagacagctg atggaatacg tgtattttga
     2281 ctttcgctga tttgcttaat catctcagga agtttgtgga gacgttgctt ggtcaaagcg
     2341 gatacaaaga taatcggtgc gtaaggcagg tattggaact gctcacggat atcttcttcc
     2401 cagtttttca tagtgtggtt atctttttca agcgtatccc acttgttgac cacgataatc
     2461 atccctttac cagcttcatg ggcaaatcct gcgatacgct tgtcgtactc acgaatgcct
     2521 tcttccgcat tgatgaccat caagaccaca tctgaacggt caatagcacg catggcacgc
     2581 ataacagagt atttctcagt attttcataa accttaccag acttacgcat accagccgta
     2641 tcaatcatgg taaactcttg accatctgta tctgtaaagt gggtatcaat ggcatcacga
     2701 gttgttccag caacaggact agcaataaca cggtcttctc ccaagatagc attgatcaag
     2761 cttgattttc caacgttagg acgaccaatc aagctaaact taatgacatc tggattttct
     2821 tcctcatatt catttggaag attttctacg atcgcatcta gcacatcccc tgtaccgatt
     2881 ccatggacag atgagatagg caatggttca cccaaaccga gagcatagaa atcatagata
     2941 tcatttctca tttcagggtt gtccaccttg ttgactgcga ggataactgg tttgtgggtc
     3001 ttataaagct tacgagctac gtattcgtct gcatcagtaa ttccttcctt accggacacg
     3061 acaaagacga taacatctgc ttcttccatg gcaatttctg cctggtgctt gatttgttcc
     3121 atgaaaggag catcgacatc atcaattcct cctgtatcaa tcatgctaaa agaacgattg
     3181 agccactcac ccgttgcata aatacggtca cgtgtcactc cttcgacatc ttctacaatg
     3241 gagattcgct caccagcgat ccgattaaat agggttgatt tcccaacatt gggacgtcct
     3301 acaatggcaa tagttggtag ggccataatt tctcactttc tacaataatt tcttctgttc
     3361 aagatttttt ctagttgagc ttggttcagc ttgaccaaac tgttctgcta ggcgctgact
     3421 ccagcttgtg gtcgcacgcg ccccagcata gtcagcctga acacggtcat aagcttggat
     3481 tgcctcagtt gactgttctt ggtattcttc ctcaaagact acattatcta gtggcagtct
     3541 tggtttcaca tcatgagttt gatttggaac acctagtgcc atcccaaaga caggataggt
     3601 gtagtcaggc aggttaaaga gttctgccac ttcttctgac ttgtaccgta ccaagccaat
     3661 aatcacacca ccataaccca aactttcagc tgccagcagg gcattttgtc cagccaaagc
     3721 cgcatccacc gaactaatca agagaccttc tacaccttgg ggttggaatg agtcagtatg
     3781 aagctgggct cccttttctg ctcggttcaa atctccgaca aagagaagga aaacagcaga
     3841 ctggcgaata gcttcttgag gtaccaattc atacagagta tctttctttt cttgacttcg
     3901 taccacaatc acagagtagg attggaaatt cttccaagac gaagccatct gggctgctgt
     3961 caggatttca gtcaaatctt cctgaggaag gtcttgctcc ttaaatctgc gcactgaagt
     4021 gtgagccttc attaatttga tggtttctgt catcgacggt ttactccttc taaacgagtc
     4081 tcctcagcca aataacggat gcgttccatg acgcgtctgg cttcccaggt ttcgtcattt
     4141 ccatttttcc ctttagcgaa atgcttctcc aaatcttcaa agttgaagtt ggatgtgaaa
     4201 aaggtcggta aattttcctg catccgatat tggagaatga cctgcaggat ttcatcacgc
     4261 acccaagcgg tggattgctc ggcaccaata tcatctaaaa tcaggacttc agaaagctta
     4321 atctcatcca ctaaggtctt aacattgcca tcaccgatag catttttgac atcaatgaca
     4381 aagctaggat agtggaggag agtggatgat acaccacgtt tttctgataa atcatgagct
     4441 agggcagcca ccatgaaact tttacccaca ccaaagtctc catacaagta aagacctttt
     4501 cgaatagctg gatattgctc cacaaaggct aatagttttt caaaaactgg caagcgcccc
     4561 aaatcatcca agtcaacttg agccaaacta gctttcttga gactggctgg tagattgatt
     4621 aacttgagac ggttcttaat agccgcttct ttttccgccg cgattagttc aggagtttct
     4681 tcatatgaaa catctgcata gccatgattc ttaaccaaaa tcggcttgta gcctttggca
     4741 atataatccg tatccccacg gagaaacttg tcacgctcgg tgatgtactg attaaacttg
     4801 gagatactgc gatttaattc ctttggagtt aaggattctt gctggataaa ggccgcaaca
     4861 tcagggtcct tcatgatttt ctggaccaaa tcttgataat gaaaacggct gggttgacgt
     4921 ttgagtacgt ctccgacact ttccatctaa tctcctcctt tttctaatcg agctaatagt
     4981 tcttgcttct tacgttctag ttccagacga gtttcctcgc tggtttcatt cttatattca
     5041 ggattactcc atttaggaat attggttttt gctggggcag tctgattctg tttttgtgtt
     5101 tttgttttct gccctcgctc acgaattcgt aaaacggcct cttctgccga atgaatcttt
     5161 tgataggcat agtcattggc taccttcatg gcatatttct cattgatatt tgccgaatcc
     5221 accttattaa aggtcaataa gagaataata ttgatgactt cgtccagtaa gcccaagcca
     5281 gccatctgtt gcaagaggtc tctttctgtt tgggtaatgg ttcccttgcg tgtttgcttg
     5341 atttctgata agaactgcag ggtagtttta cttttagctt ctttgataat ggtcgcttcc
     5401 ttaagactaa agtcagagga aactggtttt tgagcaattt tttcacgcat gcgtttggtt
     5461 gaaataacct gggaaacagc tgttgacttg gccaattgat aggtttcaaa ccaagtccat
     5521 ttcttctcct cggcaatagc aaagaggttt aagacatcgg actgctcatc cgcaaaacga
     5581 agtccatctc gaaccatcag ctggcgaaaa tgttccaagt caaaatcatt ggccactttc
     5641 ttcttgagac caaggtcttc ttgactgcct agttctgcca attctggaaa gacttgattg
     5701 agtgagacag gtatttcttc accatcagca ctttcaactt tcaaatcctc cacagctaca
     5761 tcgccaatct ttttctctaa gagtctgcga taaacaggat gctccaagaa gtcttgacta
     5821 gatagaggag catggagggc tagctgataa acatccccct tttgatagag ggtcaagaga
     5881 ttaaaagcag ataagatttt caatgatttt atcagtctat ccatcccaaa gttaagatgg
     5941 ttgagaatgc ttgaaaaaag atattccttt ctaccattat cccaaaaact gattgtataa
     6001 agataaaggc tcagtgcctc ctgaccgata atcgggaggt agcactgtac cagagatgag
     6061 gtatcttgcg acacccgatt attctttaga taagaaaaac ggtcaattgg cttcatttat
     6121 ctttcctttt tctttttaga ggactgggtg atttgttgga gcaagctctc taactcactg
     6181 acatccttaa aactacgata gacactagca aaacgtacat aggtaatctc gtccaattca
     6241 gccaactcct ccatgacgag tgaaccaatg tcctcacttt gaatttcatt ttcatttcga
     6301 ccacggagtt tctgttcgat acgattgact accatgttga tttcatcact tgacacagga
     6361 cgtttctggg ctgagcggat aatcccatta aagattttat ctctggagaa ttgttcccgt
     6421 gtgccatctt ttttaacaac cactaaggtt ctttcttcta ctcgttcgta ggttgtaaaa
     6481 cggtgttggc actcgtcgca ctctcgtctt ctacgaatgg tgttcccttc ttctgcttgg
     6541 cgactatcga taacacttga cttggtagcc ccacattttg gacaacgcat cctttccctc
     6601 cttatcgttt tcttttcatt ataccatttt ttaagcgatt cccaaaacaa ttcttctttt
     6661 tgcttgacaa gttttttgtt ttgttgtatt atttaattaa gacaaaagga taagagaaag
     6721 gagactaaga tgtcctggac atttgacaac aaaaaaccca tctatttaca gattatggag
     6781 aaaatcaagc ttcagattgt ttcccataca ctggaaccca atcaacaact tccaaccgtg
     6841 agggagctag ctagcgaggc tggtgtcaat cccaatacca tccaaagagc cttatcagac
     6901 cttgaacgag aaggatttgt ctacagcaag cgaacaactg gacgatttgt gactaaggat
     6961 aaggagctaa tcgctcagtc acgcaaacaa ttatcagaag aagaattgga acacttcgtt
     7021 tcctccatga cccattttgg ctatgaaaaa gaagaactac caggcgtagt cagtgattat
     7081 attaaaggag tttaagccta tgtcattact agcatttgaa aatgtatcca aatcatatgg
     7141 agcaacacca gcccttgaaa atgtttctct tgacattcca gctggaaaaa ttgtcggcct
     7201 tcttgggcca aacggctcag gaaaaacaac cctgattaaa ctaattaatg gcctcttaca
     7261 accagatcaa ggacgtgtcc tcatcaacga catggaccca agcccagcaa ccaaggccgt
     7321 tgtagcttat ttgcctgata cgacctatct caatgagcaa atgaaggtca aagaagccct
     7381 aacctacttc aagaccttct ataaagattt caatcttgaa cgcgctcatc atctacttgc
     7441 agacctgggc attgatgaaa atagtcgtct caagaaacta tcaaaaggaa acaaagaaaa
     7501 ggttcaactg attttggtta tgagccgtga tgctcgtctc tatgttttgg atgaacccat
     7561 tggtggggtg gatccagcag cccgtgctta tatcctcaat accattatca acaactactc
     7621 accaacttct accgttttga tttctaccca cttgatttct gatatcgagc caatcttgga
     7681 tgaaattgtc ttcctaaaag acggaaaagt cgtccgtcaa ggaaatgtag atgatattcg
     7741 ctacgagtca ggtgaatcca ttgaccaact cttccgtcag gaatttaagg cctaagcaaa
     7801 ggagattatt tatgttttgg aatttagttc actacgaatt taaaaatgtt aacaagtggt
     7861 atttagccct ctacgcagcc gtgctagtcc tttctgccct catcggaata cagacacaag
     7921 gctttaaaaa tctaccttac caagaaagtc aggctactat gctacttttt ctagctacag
     7981 tctttggtgg cttgatgctt acacttgcga tttcaaccat tttcttgatt attaaacgct
     8041 tcaaaggtag tgtctacgac cgacaaggct atctgacttt gaccttgcca gtttctgaac
     8101 accatatcat cacagccaaa ctaatcggtg cctttatctg gtcattgatt agcaccgctg
     8161 tattggctct aagtgctgtt attattctgg ctttaacagc tccagaatgg attcctcttt
     8221 cttatgtgat tacatttgta gaaacacatc tccctcagat ctttcttaca ggtatatcct
     8281 tcctactaaa taccatttca ggaatcctct gcatctacct ggctatttcc attggacagc
     8341 ttttcaatga ataccgtaca gcactcgctg ttgcagccta cattggtatc caaatcgtca
     8401 ttggatttat tgaacttttc ttcaatctta gttctaattt ctatgtcaat tcactggtag
     8461 gactcaatgg ccatttctat atgggagcag gtatagccat tgttaaagaa ctcatattca
     8521 tagctatctt ttatctcgga acctactaca tcttgagaaa taaggttaat ttgctttaaa
     8581 taatttttac ctagatatgt aacatactca tagaacaaaa gagaccaggc aaaaagtctt
     8641 taaaattaga aaacgcatag tatcaagtgt taaaaatcct tgatattatg cgttttttgt
     8701 gagttgactt atttcctttc actatatcgc aaaatgaaat aagaacggaa cgatgggatt
     8761 ttggaattca aatcaatttg taagaatgtt ttagaagtaa tattatccta ttccagattc
     8821 agttcactat acaattgagt tttcaagcaa cttgtttaca taatgtgtac ataattaggt
     8881 tcgtgattcc acccttttca cctttaaaaa cctcgctttc gcaaggctct tctatttata
     8941 agataaggca cgtttaaagg ttttccaaat ccctaaatca tccgtttgaa gaacgagact
     9001 agcatacatg cgtccgataa atcctgttgc taccaccgca aaaatcactg taatagcaag
     9061 tgaaatccat gcttccgctc cccccgcata gccattaatc gttcgaaacg gcataaagaa
     9121 ggtcgaaata aagggaatat aagaaccaat cttcaagagg agattgtcac cagctgcacc
     9181 tagagctgtc actccaaaaa aaccacccat aatcaaaatc atcaaaggcg acaaggcttt
     9241 ccctgagtcc tcaggacgag aaaccataga tcctaggaag gctgccaaga ctacatacat
     9301 gaaaagactg atcaaaataa agagcagggt attcagtgag atagcatctc ccaagtgatc
     9361 caaaatacca gactgagcca agaatggcaa atctttaaag agcaaaacgg cagccagacc
     9421 acctacaaca tagatcccaa tatgcgttaa aatcactaga aacagagcca tcatccgcgc
     9481 atagaaatag tgacttgccc ttatgctaga aaaaacgact tccataattt tggtgccttt
     9541 ttcactggca acttcctgag ctgttacacc cgcataggta atcagaatca tataaagaaa
     9601 gaatcctaag gcacctgctg caattgtttg aataaacttt ttattttcct tggcttcatc
     9661 aatcttttct gtgaattgaa ttgtctgcgc taagcgtttt tcctgctctt gagacaagga
     9721 agcagttgaa cgattaagct gattttgcag ttcattgagt gtacctgtaa cctcaaattt
     9781 aattccattt tcaagcgatg tttcgccatg ataaactgcc tttagaacac tatcttcttg
     9841 atcaatggtc aaataacctt ttaatttttc ttctttaatt gcttctttgg cacttgcttc
     9901 gtctttatag tcgaagttaa caccatttac attcttcagt ccttctgcta cagatggcac
     9961 tgttgtcact actgccactt tattattttt agccatagaa gaaccttgga gatgcccaat
    10021 tcctacagag attcctaaaa agaggaacgg cgaaatcacc ataaagaaga aactccatga
    10081 ctcgacatgt cgaagatagg tttccttgat tacaacccac atatttctca tacttccact
    10141 cctgattcta gtttaaagat ttcatcgata gttggcgctt gttggtcaaa tgttgcgata
    10201 tattgacctt gagtcaagat tgggaagagt tcccttccag cgctctcatc ctccaaaatc
    10261 aatttccaac tgccttgttt ggtcaagctc acctgtttga catgaggaag attttccaat
    10321 tcttccttgc ttcgttcact tgaaacaaag agacgcgttt tcccgtattg attgcggaca
    10381 tcctgaactg gtccgtgcaa gaccacacgg ccatctcgga tcatcagaat atcgtcacaa
    10441 agttcctcaa cattggtcat gacatggtca gaaaagataa tggttgctcc gcgctctttt
    10501 tcctgaaaaa tgacttgttt gagcaattct gtattaactg ggtccaatcc actaaaaggc
    10561 tcatccaaga taatcaggtc tggttcatga atcagagtaa taatgagctg aatcttctgc
    10621 tgatttcctt ttgacagact cttgatttta tctgtcagct ttcctttcac ttccaacctc
    10681 ttcatccatt gagggagttt ttctttgact tctttggcat ccatgccttt tagagtcgcc
    10741 aagtagcgaa cttgttcaag aactgtcaat ttaggcatga gactgcgttc ttcaggcaga
    10801 taaccaatcc gagcataggt ctcctgacga atatcctgac catccagacc gatttctccc
    10861 tgatattcta ggaatttcaa aatactatgg aaaatcgttg tttttccagc accatttttt
    10921 ccgactagtc ccaaaatacg acctggtcgc gcttgaaagt caataccaaa caaaacttgc
    10981 ttggatccaa aacttttctc tagacttctt acttctagca tctttcacct ccgaaatttc
    11041 ttgcactcat tatactcctt tttgatagcc tttacaatga tttctgtcca tttttagaag
    11101 actattgctg tgtaaaatat agcctggagc acttttatac tcaatgaaaa gcaaagagca
    11161 aactaggaag ctagtcgtag gctgctcaaa gtacagcttt gaggttgcag ataaaactga
    11221 cgaagtcagc tcaaaacact gttttgaggt tgtggataga ctgacgaagt cagtaaccta
    11281 catacggcaa ggcgaagctg acgtggtttg aagagatttt cgaagagtat tagtgataaa
    11341 tccattatac agtagcaaac tcaatttata ccttccgctc ctcaactgtc tatttttaat
    11401 cctgaattgt tatttgagta actccttttt cctcataaag ttttcttcct ctaaaacttc
    11461 tggaaaaagg cgaatagttt cagacaacat ttttataaga aacaagttca tctgtcattt
    11521 caagaaggag taatccttta tttactaatg gacggaacgg aattcaaccg cttgtccgat
    11581 atgttttcta aagattatat agtaaaatga aataaaaaca ggacaaatag atcgggacag
    11641 tcaaatcgat ttctaacaat gttttagaag cagaggtata ctattctagt ttcaatctgc
    11701 tatatctatt atgcacaccc ctataggatc taatgaaaat cacaacaggc tcattcatag
    11761 atggttacct aagcctaagg gaactaagaa aacgactacc aaggaagtcg cattcatcga
    11821 aaagtggatt aacaactatc ctaaaaaatg cttgaactac aagtccccca gagaagactt
    11881 ctggatgact aacttgaact tgaaatttag caataattaa ttcaccatct aactatattt
    11941 agtaattatt tcagaactga ttaatattaa aattaactaa cgattcaaag gattcatact
    12001 agccataaat tacgtccatc aaagagagac tcttactact tttagatttt agtctttcta
    12061 gcttcagaat acatctaaac tttagggaaa atgactattc gaaagcgcga atgcctcaaa
    12121 attatctcag ataagctatt cgaaacttag aatgctttta aatttatgga attgcgatta
    12181 ttcgaaacct agaatgcata taacctttag ttgacagacc tattctaagt ctcgaagggc
    12241 tatttacttt ctattcctta tcaaaaaaga ctcattcccc ctttctcctc caaaatatgg
    12301 tatagtagaa atatactatc tatgaggagt ttacatgtca caggataaac aaatgaaagc
    12361 tgtttctccc cttctgcagc gagttatcaa tatctcatcg attgtcggtg gggttgggag
    12421 tttgattttc tgtatttggg cttatcaggc tgggatttta caatccaagg aaaccctctc
    12481 tgcctttatc cagcaggcag gcatctgggg tccacctctc tttatctttt tacagatttt
    12541 acagactgtc gtccctatca ttccaggggc cttgacctcg gtggctgggg tctttatcta
    12601 cgggcacatc atcgggacta tctacaacta tatcggcatc gtgattggct gtgccattat
    12661 cttttatcta gtgcgcctat acggagctgc ctttgtccag tctgtcgtca gcaagcgcac
    12721 ctacgacaag tacatcggct ggctagataa gggcaatcgt tttgaccgct tctttatttt
    12781 tatgatgatt tggcccatta gcccagctga ctttctctgt atgctggctg ccctgaccaa
    12841 gatgagtttc aagcgctaca tgaccatcat cattctgacc aaacccttta ccctcgtggt
    12901 ttatacctac ggtctgacct atattattga ctttttctgg caaatgcttt gacacgtaaa
    12961 aaatccgttt ggtttcccaa gcggattttg tgctttattt tgaaacttct tttgcaagaa
    13021 caaagttccc aagtgtggca gaaccatttc ctgcgactgc tggcgtcacg atatagtcac
    13081 gcacatctgg tactggtagg taaccattaa gaagagatgt aaatttctca cggacacggt
    13141 ccagcatatg ttgttgagcc atgacccctc caccaaagac aatcacgtct gggcggaaag
    13201 tcactgtcgc attaaccgca gcttgagcga tatagtaggc ttgaacatcc caaacagggt
    13261 tgttgagttc aatagtttcc ccacgtacac ctgtacgagc ttccaaactt ggaccagctg
    13321 cataaccttc tagacatccc ttatggaaag gacaaacacc cttaaactct ttttcaatat
    13381 ccattgggtg tctagcaaca taataatgac ccatttcagg gtgacccaca ccaccgataa
    13441 actcaccacg ttggatgacg cctgcaccga tacctgtacc gattgtgtag taaaccaagt
    13501 tttcgatacg accaccagca ttgttacggg caaccatttc accgtaagca gagctgttta
    13561 cgtctgttgt gaagtacatt ggcacgttta gggcgcgacg aagggcacca agcaagtcca
    13621 catttgccca gtttggtttt ggagtcgtcg tgataaagcc ataagttttt gagtttttgt
    13681 caatatcaat cggcccaaat gaaccaactg caagaccagc aaggttatcg aattttgaga
    13741 agaactcaat ggttttatcg attgtttcga ttggagttgt tgttggaaat tgtgtttttt
    13801 ctacaacgtt aaagttttca tcaccgacag cacagacaaa ctttgtaccg cccgcttcca
    13861 agcttccata taattttgtc atgataaacc tcttgttttt attttcttta ttatagcata
    13921 cttcgaaagt ctaaatgtct ctatttttta gattttcctc tgtaaatctt actatctaat
    13981 aaaaacgaac aaacatgtca tttgttcgtt ttcacattag agaggattga ttagattttc
    14041 acttcgatca cagcattccc cttcgcaact gaacctgttg cgactggagc tactgaagcg
    14101 tagtcagctg tatttgtaac gataaccatt gttgtatcat caagtccagc tgcagcgatt
    14161 ttgtttgagt caaatgttcc aagaacatcg ccagctttca ccttattacc ttgagcaact
    14221 tttgcttcaa aaccgtcacc gttcatagat acagtgtcaa taccaacgtg aatcaaaact
    14281 tcagcaccat ttcttgtttt caaaccaaaa gcgtgccctg ttggaaaggc aattgaaact
    14341 tcagcatcag ctggtgcata gaccacgcct tggcttggtt tcacagcgat accttgtccc
    14401 atagctccac ttgagaagac tgggtcattg acatcagcaa gagcgacaac atcaccaacg
    14461 ataggagtta caagtgtttc attttgaaga gctgctggcg caacttcttc tttttcttca
    14521 gccacttcag cttgttttgc agctgcagtt gcgtctactt catcttcgta accaaacatg
    14581 taagtaagag caaaaccaag ggcaaatgat acagctacca taagaaggta ttgtggaagt
    14641 tgtccgttac caacataaag cattgtacca gggatgatgg tgataccatt accagtacca
    14701 gcaagtccaa ggatagaagc caatccacca ccgattgcac cagcaatcaa tgaaaggaag
    14761 aatggtttac ggaagcgcaa gttcaccccg aagatagcag gctctgtaat acctaggaag
    14821 gcagaaagag cagccgggaa agcaagtgtt ttcagttttg gattttgtgt tttaacacca
    14881 accgcaacag tagcagcacc ttgagctgtc atagcagctg tgatgatagc gttgaatggg
    14941 ttagcatggt cagcagcaag taattgcact tcaagcaagt tgaagatgtg gtgcacacct
    15001 gacacgacga tcaattggtg aaccccacca atcaagaaac caccaagacc aaatggcatg
    15061 ctaagaatcg cttttgtagc aataaggatg tagttttcaa caacgtggaa aactggtcca
    15121 atgacaaaga gtccaaggat agacatgacc aaaagtgtca cgaatggtgt taccaagagg
    15181 tcaatgacat ctggaacaac cttgcggaca gctttttcaa atttagctcc gacaaccccg
    15241 atgatgaagg ctggaagaac ggaaccttgc aaaccaacaa cagggatgaa accaaagaag
    15301 ttcatcgctg ttacttcacc accttgagca actgcccaag cgtttggaag tgagccagag
    15361 acaagcatca taccaagaac gataccaacg gcaggatttc caccaaatac acggaaggtt
    15421 gaccacacaa ccaaacctgg caagatgatg aaggctgtat ctgtcaagat ttgtgtgtaa
    15481 gttgcaaagt cacctggaag tggcatttca agagcgttga aaagaccacg cacacccatg
    15541 aagagacctg tcgctacgat aactgggatg attggaacga aaacatcacc aaaagtacgg
    15601 atagcacgtt ggaaccagtt cccttgttta gcaacttctg ctttcatgtc atccttagat
    15661 gatgttggta atccaagtac aacaacttca tcgtacattt tgttaactgt acctgtacca
    15721 aagataattt ggtattgccc tgagttaaag aaagcacctt gaactttttc caagttctca
    15781 atcacttctt tattgatttt ctcttcatct ttgaccatga cacgtagacg tgtcgcacag
    15841 tgggcaacac tattgacatt ttcacgtccg cccaaggcat cgatgacttt ttttgcaatt
    15901 tcctgattgt tcatttgcaa aaatctcctt atataacatt ttgttcttgt ttgaaagcga
    15961 ttttattcgc ccttacgact attattttat catgttttaa aaatatgtca agcgttttgc
    16021 agaaaaaata ttctatctac ttagtgggca agctttagat tgattgtttt tgactgtttc
    16081 atcaggaatt tcttgaaaaa taagtttgaa accttggtta aaaagtcttt tatttcatta
    16141 tctttcacat tttcgtaaaa atttgattga tttcctgtat ttattttatg ataatcgttt
    16201 gacagttttt tctctttttt aacataaagg gcttgcattt tttatcgaaa acagttacta
    16261 ttaaaagtga taagattttt ggaggaatga atggaatgga caactgagcg tcgttacaga
    16321 ctttatcaag attggacgca agaagaaatt caacatataa aggaaaatat ggcacaatct
    16381 ccatggcata ctcattacca tgttgagcca aaaacaggac ttctcaacga cccaaatggc
    16441 ttttcttact ttgatggcaa gtggatcctc ttttaccaga attttccttt tggtgcagcc
    16501 cacggtttaa aatcttgggc acagctagaa agtgatgatt tggttcactt tagagaaact
    16561 ggagtcaaag ttttgccaga tactccatta gatagtcacg gtgcctactc tggttctgcc
    16621 atgcaatttg gcgataactt attcctattt tatacaggaa atgttcgcga tgaaaactgg
    16681 atccgtcacc cataccagat cggtgctttg atggacaagg agggtaagat tacaaagatt
    16741 gacaagatct tgattgacca gccagcagac tctactgacc acttccgcga tccacaaatt
    16801 tttaacttta aaggtcaata ctatgctgtc gtcggtggac aggacttgga gaaaaaaggc
    16861 ttcgtccgtc tctacaaggc tgtcaataac gactacacaa actggcaagc agttggcgac
    16921 cttgactttg ctaacgaccg tactgcctac atgatggaat gtcctaatct ggtctttgta
    16981 gaggaacagc ctgtccttct ctactgtcca caaggattgg ataagaaagt tctagactac
    17041 gataatatct ttccaaatat gtataagatt ggggcttcct ttgaccctaa aaatgccaaa
    17101 atggtagatg tgtctcaact tcaaaacatg gattacggtt tcgaagccta tgcaactcaa
    17161 gccttcaacg ctcctgatgg gcgtgctcta gcagttagct ggcttggttt gccagatgtt
    17221 tcttacccat ctgaccgttt tgaccaccaa ggaaccttct ctttggtcaa ggaactcact
    17281 atcaaagacg acaagctcta ccagtatcca gtcgctgcta ttaaggacct tcgtacttct
    17341 gaagaagcct tctcaaaccg ttcccaaacc aagaacactt acgaacttga actcaacttg
    17401 gaagctaata gccagagcga gattgtctta cttgctgata aagaaggtaa gggactttca
    17461 atcaactttg accttgtaaa cggtcaagtg acagtggatc gtagccaggc tggagagcag
    17521 tatgcccaag aatttgggat aactcgttct tgccctatcg agaatcaggc tactactgct
    17581 acaatcttca tcgataactc tgtctttgaa attttcatca ataaaggaga aaaagtattt
    17641 tctggtcgtg tcttcccaca tgcggaccaa aatggtatcc tgatcaaatc tggaaaccca
    17701 actggaactt actatgaatt agattatggt cgcaaaacta actgatgtcg ccaaacttgc
    17761 aggcgtcagt cctactaccg tttctcgggt tatcaataaa aaaggatatc tatctgagaa
    17821 aaccatccaa aaagtcaatg aagccatgcg agaattgggc tataaaccca acaacctggc
    17881 tcgtagtctg caaggaaaat cagctaagtt aatcggcttg attttcccca atatttccaa
    17941 tgttttctat gcagaattga ttgataaatt ggaacaccaa ctcttcaaaa atggttacaa
    18001 gaccatcatc tgcaacagtg aacatgattc tgagaaggaa cgtgaataca tcgaaatgtt
    18061 ggaagccaat caggtggacg gcatcatttc tggtagtcac aacctaggaa tcgaagacta
    18121 caatcgtgtg acagcgccga ttatttcctt tgaccgaaac ctatcgccag acatccctgt
    18181 cgtctcctct gacaactatg ctggtggggt tcttgctgcc caaaccttgg tcaagacagg
    18241 tgcccagtct atcatcatga ttacagggaa tgacaattcc aattcgccaa ccggactgcg
    18301 ccacgctggt tttgcatccg tactcccaaa agctcctatt atcaatgttt ccagtgactt
    18361 ttctcccgtc agaaaagaaa tggaaatcaa gaatatcttg acccgggaaa aaccagatgc
    18421 catttttgct tcggatgatt tgacagctat tctggtcatt aaaatcgctc aagaattggg
    18481 catttctgtc ccaaaagagc tcaaggtcat cggctatgat gggacctact ttatcgaaaa
    18541 ttactaccct caattggcta ctatcaagca acctttggaa gagattgctt gtctcactat
    18601 tgatcttctc ttgcaaaaga ttgaaggcaa ggaagtcgcc acaactggtt acttcttacc
    18661 agttacacta ttaccaggaa aaagtattta aacacaagaa aactcagacc gattcgtctg
    18721 agttttttat gatcttaaat tttcgagata gcgctgggct gtctctaggt taaaggtttt
    18781 atctgagatg aggcgctcta ctaggggagc aacttcagat tcactagccc cagctaggag
    18841 agctagggat ttggcctgta gtttcatgtg gccttgctgg atgcccgtac ttaccaaggc
    18901 tttgagggct gcaaaatttt gggcaagacc gatggacacg ataatctggg ctaattctct
    18961 ggcagaagga tttcctagta gatcatgact gagagctaca cgtgggttga ggccgataga
    19021 gccaccctta gtcgctacag gcatgggcag ggtcatctca ccgaccaatt cttctctttc
    19081 aaggtccagc gtccagcagc taagaccttg atagcgtcca tctcgactgg caaaggcatg
    19141 ggccccagct tcgatggcac gccagtcatt accagtggca atcaaaatcg catcaatacc
    19201 attaaaaatt cctttattat gagtagcagc tcggtaagga tcagcctgcg caaactgact
    19261 agccaacgca attttctccg caatctctcg tccttgatcc ttttggcggc tcaagtagcg
    19321 aaaggcgatg cgacagcttg cagtcaccag agaatcggtc gcgtagttgg acaggattgc
    19381 catgagactc tgtccctgac tgagttcttc taagactggt ttcaaggctt ccagcatggt
    19441 gttgagcata ttggcaccca tggcttcctg ggtatcgaca tgaatataaa caacgagaaa
    19501 gtctggttca ccttttatct gctcgacatg cagatcacgc gccccacctc cacgtttaac
    19561 gatagaagga taggcttgat tggcaagctc caagagctcc gctttcttgc tggcaatctt
    19621 ctcttgcgct agtttaggat tagcaacttg ataaagggct acctgcccaa tcatctgtcg
    19681 ctgatggact tgtgcagtaa aaccacctgc acgcttgatg attttgctgg catagctggc
    19741 cgccgcaacc acagagggtt cttctgtcac atagggaacg gtgtattcct gaccgttgac
    19801 aagtacctcc ggaaccagtg aataaggcag agaaaaagtt cccactacat tctcactcag
    19861 ctggtctgcc acagtcacgc tcatctgttc atccttctcc agactagctt gtctctcagg
    19921 actaaggagc gcctgagctt ttaacagctc gaggcgctct tggtatgatt ttttagaaaa
    19981 tccattccaa cttatcttca ttatttttca accttgctat aacggcgttg gtggtcgaga
    20041 atttcaacca aggcaaaatc ttgattttca tagccagcaa actgggcaga gtttgtttca
    20101 tccaagttta cttcctcaaa aaagaccttt tcatagtctg caacggatag ggcagttcgt
    20161 tggttgagct tgttcaagcg gtctttatcc aaataagctt catatccttc aaccaattca
    20221 ccactgaaga actcagccac agctccactt ccgtaactat aaagggcgat tttatcccca
    20281 gctttcaagc tatctgtatt ttccaagaga gacaaaagtc caaggaaaag tgaacctgtg
    20341 tagatattcc ccaccttttg actgtagaga atagactggt caaaatgctt ttgtaagagg
    20401 tcttttttct cttgaggcag gctcttatcc atgatttttt tcaagccttt tagcgctaat
    20461 ttaggataag gcaagtggaa acaaacagcc gcaaaatcat ccaaagtaag ctggtagcgt
    20521 ttttgatatt caagccaagt cgttttcaaa ctatccaagt attgttgggt agaatagaca
    20581 ccatttacat aaggagttgt cgagtaattt ggtcgccaga aatccatgat gtcacgggtc
    20641 tgagctacat tgtcattatt aaaggccatc atgcgtggat tttgtgtaat caacatagct
    20701 acacttccag caccttgagt tggttctcct ggagtttcaa taccgtattt ggcaatatca
    20761 ctggcaatga ccaagacctt ggactccgga gaattttcca catgcaattt ggcataatgg
    20821 agggcagcag tcgctccgta gcaggcttct ttaatctcga aactacgagc aaagggctgg
    20881 atgcccagca agccatgcac aaagacggcc gcagccttac tctggtcaat tcctgactcg
    20941 gtagccacaa tgaccatgtc aacttcttgt ctttcttgct cagttaaaat agagtcacta
    21001 gcactggccg ccaaggtcac gatgtcctca gttaggggcg caatactcaa ttccttgagt
    21061 aagagtcctt tacttaattt ttcagggtca attcccctcg cttctgctaa gtcttgtaat
    21121 ttcaagacat attgactggt cgcaaaacca atcttatcaa taccgattgt catatttacc
    21181 tctgttttat cattcatgta aaaaatcgtt ctatactatt ttatcacaaa tggcagtaaa
    21241 agagagaaaa aagacttgat tcaccaaatc aagcctctta ttggtcatca ttttaaagaa
    21301 tgattagttg ctagagagtt caccgatata agtagcttta taagctccat tcacagttat
    21361 cagctcctgg aggatcaaat ttcctgagta agtccttccc atctcatcta caaatttttg
    21421 ataaaactga ctggtcggaa tttctctgac atccttatca aatgtcttgt caagtgtttt
    21481 actaaccttc tcagcaatca attgatgctc ttgccatcca ctttgaaact ctgagcccca
    21541 actagaaacc atgactggga taaacaacaa ggtcagtaga cttacagaca ataaggaaaa
    21601 tagtagactt cctgcgaaac caaaatccta gttcatgatt gataatacca gcaatcaaat
    21661 tcattcgtaa tccgaagcgt ttacgatgat ttcgataggt tgttgaaaac attttaaacg
    21721 tttttacttt ggcaaagatg ttctcaacct tgcttctctc cttagatagc gcatggttat
    21781 aggctttatc ttcagctatt agcggcttga gtttgctgga tttacgtgga gtttgtgctt
    21841 gaggatatat cttcatgagt ccttgataac cactgtcagc caagattttt ccagcttgtc
    21901 cgatatttct gcgactcatt ttgaacaact tcatatcat
//
