LOCUS       NZ_CLHL01000006        17824 bp    DNA     linear   CON 30-NOV-2024
DEFINITION  Streptococcus pneumoniae strain SMRU2163, whole genome shotgun
            sequence.
ACCESSION   NZ_CLHL01000006
VERSION     NZ_CLHL01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  AUTHORS   Informatics,Pathogen.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAR-2015) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001094205.1-RS_2024_11_30
            Annotation Date                   :: 11/30/2024 00:46:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,213
            CDSs (total)                      :: 2,163
            Genes (coding)                    :: 2,009
            CDSs (with protein)               :: 2,009
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 68 of 154
            Pseudo Genes (incomplete)         :: 85 of 154
            Pseudo Genes (internal stop)      :: 43 of 154
            Pseudo Genes (multiple problems)  :: 34 of 154
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:27:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 17824
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CLHL01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..17824
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..17824
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..17824
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[6948:7824](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(6949..7824)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(<1..128)
                     /locus_tag="AE723_RS11630"
                     /pseudo=""
     CDS             complement(<1..128)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="AE723_RS11630"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNDEASKQLTDARFKRLVSVQRTTFEEMLAVLKTAYQLKHAK"
     gene            complement(136..438)
                     /locus_tag="AE723_RS04725"
                     /old_locus_tag="ERS021673_00913"
     CDS             complement(136..438)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /locus_tag="AE723_RS04725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00913"
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="WP_000590581.1"
                     /transl_table=11
                     /translation="MIKILAACGAGVNSSYQIKSALEEELSNRGYDVHCDAVMVKDVNE
                     DLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            complement(476..952)
                     /locus_tag="AE723_RS04730"
                     /old_locus_tag="ERS021673_00914"
                     /pseudo=""
     CDS             complement(476..952)
                     /GO_component="GO:1902495 - transmembrane transporter
                     complex [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /locus_tag="AE723_RS04730"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00914"
                     /product="PTS sugar transporter subunit IIA"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVLDYFFDKNLVFCLEADNQE"
     gene            1133..1330
                     /locus_tag="AE723_RS12980"
                     /old_locus_tag="ERS021673_00915"
     CDS             1133..1330
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AE723_RS12980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ERS021673_00915"
                     /product="hypothetical protein"
                     /protein_id="WP_000693247.1"
                     /transl_table=11
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDETDEVSSKHGFEVVDETDEVSN
                     HTYGKATLTWFEEIFEEYKN"
     gene            complement(1411..3234)
                     /gene="lepA"
                     /locus_tag="AE723_RS04740"
                     /old_locus_tag="ERS021673_00916"
     CDS             complement(1411..3234)
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="lepA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /locus_tag="AE723_RS04740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00916"
                     /product="translation elongation factor 4"
                     /protein_id="WP_001047212.1"
                     /transl_table=11
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREM
                     QAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAAC
                     EGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLD
                     ASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVM
                     DGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGD
                     TVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETS
                     QALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEF
                     PDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLA
                     EIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYER
                     GKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLE
                     KQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(3313..4041)
                     /locus_tag="AE723_RS04745"
                     /old_locus_tag="ERS021673_00917"
     CDS             complement(3313..4041)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /locus_tag="AE723_RS04745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00917"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_050150244.1"
                     /transl_table=11
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSHR
                     VLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLDAP
                     VDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKVWLR
                     KPFHGSENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLHGIVF
                     TDQGMTEHHFIENDGFVAED"
     gene            complement(4043..5710)
                     /gene="recN"
                     /locus_tag="AE723_RS04750"
                     /old_locus_tag="ERS021673_00918"
     CDS             complement(4043..5710)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /locus_tag="AE723_RS04750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00918"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_000923573.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNMM
                     LGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGRSI
                     SRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKETYQT
                     SFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDKLLNH
                     KNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYYVLEDI
                     SKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEYNLLTGN
                     NLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKAQFQVRFS
                     KGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKEGKTSIVFD
                     EVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKISNDHSTVSTV
                     RLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            complement(5717..6148)
                     /locus_tag="AE723_RS04755"
                     /old_locus_tag="ERS021673_00919"
     CDS             complement(5717..6148)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /locus_tag="AE723_RS04755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00919"
                     /product="arginine repressor"
                     /protein_id="WP_001034415.1"
                     /transl_table=11
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRDI
                     KELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVKAQ
                     LIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            complement(6141..6956)
                     /locus_tag="AE723_RS04760"
                     /old_locus_tag="ERS021673_00920"
     CDS             complement(6141..6956)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /locus_tag="AE723_RS04760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00920"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_001041079.1"
                     /transl_table=11
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPGE
                     KIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQNS
                     AKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISLSLI
                     LPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEVGFSV
                     LGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            complement(6949..7824)
                     /locus_tag="AE723_RS04765"
                     /old_locus_tag="ERS021673_00921"
     CDS             complement(6949..7824)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /locus_tag="AE723_RS04765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00921"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_000743819.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-57, bitscore:
                     188.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRPF
                     LLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFGEA
                     MAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQHLS
                     LEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVLDVTA
                     SFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFETESIV
                     SVVESLRING"
     gene            complement(7821..8033)
                     /locus_tag="AE723_RS04770"
                     /old_locus_tag="ERS021673_00922"
     CDS             complement(7821..8033)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /locus_tag="AE723_RS04770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00922"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_000043230.1"
                     /transl_table=11
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKEL
                     QATLDKAEKTLVKVMQEDGTESDFE"
     gene            complement(8011..9351)
                     /gene="xseA"
                     /locus_tag="AE723_RS04775"
                     /old_locus_tag="ERS021673_00923"
     CDS             complement(8011..9351)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /locus_tag="AE723_RS04775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00923"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_000417464.1"
                     /transl_table=11
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYF
                     SLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGVG
                     ALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGV
                     DILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIF
                     ESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMVTA
                     VRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQA
                     RTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIV
                     ARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            complement(9479..10117)
                     /gene="udk"
                     /locus_tag="AE723_RS04780"
                     /old_locus_tag="ERS021673_00924"
     CDS             complement(9479..10117)
                     /EC_number="2.7.1.48"
                     /GO_function="GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="udk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /locus_tag="AE723_RS04780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00924"
                     /product="uridine kinase"
                     /protein_id="WP_001181378.1"
                     /transl_table=11
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKD
                     QSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEP
                     QDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLG
                     VVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     misc_feature    10157..10171
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
     gene            complement(10225..10527)
                     /locus_tag="AE723_RS04785"
                     /old_locus_tag="ERS021673_00925"
     CDS             complement(10225..10527)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /locus_tag="AE723_RS04785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00925"
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_000985089.1"
                     /transl_table=11
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSV
                     MANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            complement(10768..11646)
                     /gene="truB"
                     /locus_tag="AE723_RS04795"
                     /old_locus_tag="ERS021673_00927"
     CDS             complement(10768..11646)
                     /EC_number="5.4.99.25"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /locus_tag="AE723_RS04795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00927"
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="WP_001013241.1"
                     /transl_table=11
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVL
                     PIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDEAI
                     ASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDGQLA
                     RFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAEKVEA
                     GQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLAILEKR
                     GNLYKPRKVFS"
     gene            complement(11656..12930)
                     /locus_tag="AE723_RS04800"
                     /old_locus_tag="ERS021673_00928"
     CDS             complement(11656..12930)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /locus_tag="AE723_RS04800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00928"
                     /product="DUF2130 domain-containing protein"
                     /protein_id="WP_001002614.1"
                     /transl_table=11
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQELA
                     LAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEVQL
                     LENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQLKAA
                     SEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGSKGDF
                     IFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLVTMLEA
                     DNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVREQNIDIT
                     HFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQLRLANNKL
                     EDVSVKKLTRKNPTMKAKFEALKGE"
     gene            complement(13026..14285)
                     /locus_tag="AE723_RS04805"
                     /old_locus_tag="ERS021673_00929"
                     /pseudo=""
     CDS             complement(13026..14285)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /locus_tag="AE723_RS04805"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00929"
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            complement(14433..15230)
                     /locus_tag="AE723_RS04810"
                     /old_locus_tag="ERS021673_00931"
     CDS             complement(14433..15230)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /locus_tag="AE723_RS04810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00931"
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_000254797.1"
                     /transl_table=11
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTAA
                     GAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISWRK
                     TAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLEAIL
                     ANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVAADSI
                     ANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            complement(15475..16218)
                     /gene="srtA"
                     /locus_tag="AE723_RS04815"
                     /old_locus_tag="ERS021673_00932"
     CDS             complement(15475..16218)
                     /codon_start=1
                     /gene="srtA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /locus_tag="AE723_RS04815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS021673_00932"
                     /product="sortase SrtA"
                     /protein_id="WP_000078847.1"
                     /transl_table=11
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVWN
                     TNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPELE
                     MNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNAKNG
                     MKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIVKGDL
                     KETKDYSQTSNEILTAFNQPYKQFY"
ORIGIN
        1 ccttttgcgt gtttaagttg ataagctgtt tttaatacag ctaacatctc ttcaaaagtg
       61 gtacgctgaa cactaacaag acgcttaaat cgtgcatcgg ttagttgttt acttgcttca
      121 tcattcatag aactactata ccatgttttg tttcgcagga agtctaatat tgtcaaatac
      181 tggaacgctc attgctggga tacggaataa gattggccca gcttcgataa ctgggatacc
      241 tggttcaaaa ccaaggtctg ttgcagcgat tggtgtaaag atatcgtaac ctttcataag
      301 gtcttcgttt acatctttca ccatgactgc atcacagtga acatcataac cacggtttga
      361 aagttcttct tctagagcac ttttaatttg gtaacttgag ttaacacctg caccgcaggc
      421 agcaagaatt ttaatcattt ggatttcctc cgattttatt ttttaataga caagattaag
      481 cggttgcttc agcaatgtaa gcataaagtt tttctggttc ggaaattttt gatagatctt
      541 caagatgtcc atttcctgtg aaaaagtcca tcaactgagc cagaatattt gtttgacttg
      601 aacttgaatt gttaatgata aagaagagta gggatacttc tacttcctta tcaggagcta
      661 tcatattgtg aaaagttact ggtttttcta atcgaacaac caccactttc tcagctagat
      721 tatgaacaat atctgtatga ggaatcgcta catttggcaa gtcctttcct agaaattcca
      781 tatctaaacc agttggaaat gacttttcac gcgtgatcaa ggcttcacga taagttggag
      841 ttacaatttc tcgttcctcc aacaagcttg ctacctgatc aaagagttat tcttgattat
      901 ccgcttctaa gcaaaacaca aggtttttgt caaagaaata atctaatacc ataaggtttt
      961 cccttctttc cattaacttt atgctataag tataacacta tatgaaatcg ttgttaatta
     1021 ctttctgttc ttttttgtct ctttttttat atttttgttg tgtttatagt ttgttatata
     1081 aaagtaaaca cacaaacaaa tactccaagc attttttctg ttctaatact caatgaaaat
     1141 caaagagcaa actaggaagc tagccgcagg ttgttcaaaa cacagttttg aggttgtaga
     1201 tgaaactgac gaagtcagct caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt
     1261 cagtaaccat acatacggta aggcgacgct gacgtggttt gaagagattt tcgaagagta
     1321 taaaaactaa aaaagcagac catctaagcc tgctttacta ttgattctta tataaatttc
     1381 ctgtgaacaa ggaaaggcat ttctgataac ttattcttca tccatactca agacgctgag
     1441 gaaggcttct tgcggaactt caactgatcc gatggatttc atgcgtttct taccagcttt
     1501 ttgtttttca aggagtttac gcttacgaga aacgtcacca ccataacatt tagcaagtac
     1561 gttcttacga agggccttga tatcagtacg agcgacaatc ttgtgtccaa tagccgcttg
     1621 gattggaact tcaaattgtt ggcgagggat gattttcttg agtttatcaa cgatgagttt
     1681 cccacgttcg taggcaaagt ccttgtgaac gataaagctg agggcatcca ccttatctcc
     1741 attgagaaga atatccattt tcaccagctt agatgggcga tattctgaca attcgtagtc
     1801 aaagcttgca taaccacgtg tcgaagactt aagtttatca aagaagtcaa agacaatttc
     1861 agcaagagga atttgataga taacattgac acggttatca tcaatatagt ccatagtcac
     1921 aaagtcccca cgcttacgct gagctagctc cattactgct ccgacgaact cctgtggtac
     1981 catgatttgc gccttgacat aaggctcttc aatggtcgca atcttagttg ggtctggaaa
     2041 ctcagatggg ttagacacat ccatagactc accgtcggtc aaattaactt tgtaaataac
     2101 agacggagct gtcatgatga ggtcaatatt gaactcacgc tctaaacgtt cctggataac
     2161 atccatatgg agaagtccaa gaaatccaca acggaaacca aatccaagtg cctgagatgt
     2221 ttctggttca aactgaagac tagcatcatt cagttgcaat ttttcaagcg cttcacgcag
     2281 gtcattgtac ttgtttgatt cgattgggta gagacccgca aagaccatag gattcatctg
     2341 cttataacca tgtaatggtt ctgccgcagg attggttgcc aaggtaacgg tatcacccac
     2401 acgagtatcc tgaaccgtct tgatagacgc cgcaatgtaa ccaacatcac cagtcgcaag
     2461 gaaatcacga ccaaccgctt ttggtgtaaa aataccgact tcggccacat caaaggtctt
     2521 actattgctc atgagctgaa tcttatcacc aggtttgacc actccgtcca tgacacgcac
     2581 ttggaggata accccacggt aagcatcgta aacagagtcg aaaatcaagg ccttaagtgg
     2641 cgccgtcaca tcacccgttg gtgctggtac tttttctaca atttgctcga ggatttcttc
     2701 aatcccaata ccagccttgg cagaagccaa aactgcttca ctggcatcca aaccaatcac
     2761 atcttcaatc tctgtacgca cgcgctccgg atctgcagcc ggcaggtcaa ttttattaat
     2821 gataggcatg atttccaaat cattatccaa agccagataa acgttggcaa gagtttgagc
     2881 ctcaattcct tgagccgcat cgaccaccaa aatagcaccc tcacaggcag ctagcgaacg
     2941 tgaaacttca taggtaaagt caacgtgccc tggtgtgtca atcaagtgga aaatataagt
     3001 ttccccatct tttgcagtgt aattcaactc gatggcattc aacttaatag taattccacg
     3061 ttcccgctct agctccatgc tatccaaaag ctgggcctgc atttcacgac ttgaaaccgt
     3121 ctctgttttt tccaaaatgc ggtctgctag agttgatttt ccgtggtcaa tatgggcgat
     3181 aatagagaag ttacggatct tctcctgtcg ttttttcaat tcttctaagt tcatgattct
     3241 cttcctttca gggtatctat ttattataaa ttgtttttga tattttgaca agaccatacc
     3301 ctgctaggag tactaatctt cagcgacaaa gccgtcattt tcgataaagt ggtgttctgt
     3361 cattccttgg tctgtaaaga caatcccgtg aaggacacca ccataaacag ctcctccatc
     3421 cattccaatc ttgccatctt ctgtagtcca aagctcagat gtaccgcgtt cttgctgtaa
     3481 caaaccatag accggtgtat gaccgaagac aatggttttt ccagtatgat tttcagatcc
     3541 gtggaatggt tttctaagcc atactttttt ataatctgtt gtttcatgcc agtcgtccaa
     3601 ggtcaaatca atacctgcgt gaacaaagat atacttgtct gtctctacta caaatggcat
     3661 ttgacgaatg aattcgacca agtctgccgc ttcagcggca acccgcttgg catcttctac
     3721 tccatcaact ggtgcatcca agggacgacc taggatagag ttaatggttg tatctccacc
     3781 attgcgacta taatggtcat aactttcttc tgggtcatct agccaagtca aaaacatata
     3841 ctcgtggttt ccggacaaac agatagcccc ttgattgtcc accaagtcct tgaccatttc
     3901 aagaacacgg tgactatcct cacctctgtc aatcaaatca cctagaaaga gcaactgggg
     3961 ctgaccatcc caggttttga gaaggtcttc cagcatccca gcttttccgt gaacatctcc
     4021 aattacataa taatctgtca tcttatttct ccctgtttct caacaattct cttgcttgcg
     4081 tcagggctgc ttctgtcaca tcatcacctg ccaacatctt ggcaacttcc tccactcgct
     4141 cttcgaccgt caagagacga acagtcgaaa ccgttgaatg gtcattacta atcttctcaa
     4201 taaagaattg ataatctgca atcgcaatta cttgtggcaa atgggagata gccaaaacct
     4261 gaccatgctg accaatttta tgaattttct gagcaatagc ttgagcaaca cgacctgaaa
     4321 ctcccgtatc cacctcatca aagacaatgc tagtcttgcc ttctttacgt gaaaaggcag
     4381 acttaatggc taacatgaga cgagataatt cccctccaga agcaacctta accaagggtt
     4441 taaagtcttc tccagggttg gttgaaatat aaaactcaac cattttattt ccctcacgac
     4501 tgaattttcc cttactaaaa cgaacctgaa actgggcttt ttccatataa agatcttgca
     4561 gttcttgttt aatctcagct tcgagttgct gagccaaatt atgacgagca gaagcaagtt
     4621 gacctgccaa attgacaaga ttgacttcca acttcttaag ctctgcttcc atgtcctcag
     4681 acgaaagatt attgcctgtc aagagattgt attcttccgt aatcttggca aaataaagca
     4741 aaacatcatc aacagtccca ccatacttac gagtaatagt atgaaggagg tccaaacgat
     4801 tctcaacctg catcaggcga ttgccatcaa aatcaaggtc ctcaatgata gcttccaaac
     4861 gtttgctaat gtcttctaaa acatagtagg tctcagacag agagcttgaa atttcacggt
     4921 attcaggatc atactcttcg acactttcca tgtcattcat agctgaacga acattggcca
     4981 gacttgaaaa atcttcattg tccaacatac tgtaggcatt ggtcagtgta tccgcaatat
     5041 ttttgtggtt gaggagttta tctcgctctt gattgagagc caagtcttct ccagcctgca
     5101 agtttgctgc ctcaatctct gccatttgaa attccaacat ttcgatacgt gccttgtgtt
     5161 cctgttggtt tttcttgact tccagaacct gcttgcgcat tttccgatag gcatcaaaac
     5221 tcgtttgata ggtttctttc aagtcccaaa aagcggcatc accaaattca tccaacatct
     5281 ggatatgcag ttggggacgc attaactcct catggtcatg ctgaccatga atatctacaa
     5341 gatgttgccc aatagctcgc aaaacagaca gattaaccat ctgaccattt acacggctga
     5401 tactacgacc attttgcaag atttcccgac ggatgataat ttcatcacct aattctaaac
     5461 cttgctcatc aaaaatttcc tgtaaaagac gactattctc aactgagaaa agcccctcaa
     5521 tctctgcctt tggtgcacca tgacgaataa catctgtcgt cgcacgagct cccaacatca
     5581 tattcatggc atcaatgata atcgacttcc ctgcacccgt ttcaccagtc aggacagtca
     5641 tccccttttc aaaattgagg gaaatagcct caataatggc aaagtttttt atcgaaattt
     5701 caagtaacat atagacctac caatttttta cttgttcaaa gatttcctct gctagacttc
     5761 cacttctggc aatgactaaa atcgagctat catcagtcaa acagctaaaa atcttgtctg
     5821 caaaagtctc gattaactga gcttttacaa aagccgtatt tcctggaata acttggagat
     5881 tgatcatctt atccatcaat tcagccgatt cgatattgtc ttcagccagt tgcagacttt
     5941 ttacgattga ttttggcaat tcgtagacat aggtgttgtc tctcaaagga attttgacaa
     6001 tacctaactc tttgatatct cgggataccg tcgcctgagt ggcagtgata cctgcttctt
     6061 tcaaatgttc tacaatttct tcttgcgtgc cgatttgata atctgtcacc aatcttctaa
     6121 ttttttcaag tctctctttt ttattcattt ttaaattgac tatgcgccct ctctactgct
     6181 tctttaatct cagcaagaat ctgattgctt gctgactttt cttttttcaa atacgctaaa
     6241 aattcaatat ttccatgtcc accttggatg ggagaaaagt ccaagccaag gactgaaaaa
     6301 cctacctcta ctgccatagc tgttacagat tcaaggacat tctgatgaac cttagcatct
     6361 cgaataattc catttttccc aatctgctca cgtcctgcct caaactgagg tttgacaagt
     6421 gctaccacct gaccttgatc agccaagaca cggtgcaagg ctggcaaaat cagactaagg
     6481 gaaatgaaac tcacatcaat actggcaaag ctcggctcct gctcgaaatc agtcttttca
     6541 gcatagcgga aattgaactg ctccatgctg acaactcgtg ggtcttggcg taatttccaa
     6601 gccaactgat tggtaccaac atcgactgca aagaccaact tggcactatt ctgtagcatg
     6661 acatcggtaa aacctccagt agaggccccg atatcaatcg tagtcgcgcc atccaccgac
     6721 aaatcaaaga cctgcaaggc cttttccagt ttcaaaccac cacggctgac atacttgagt
     6781 ttctccccct tgagttttaa ttcggtgtca tctggaattt tctctcctgg cttgtcaaac
     6841 cgttctccat taaggactgc tacgactagg ccagccatca cacctcgctt ggcctgctct
     6901 ctcgtttcaa acaacccctg tttataagct agtacatcca ctctttcctt agccattgat
     6961 tctcaaactt tctactacac ttacaatcga ttctgtttca aagggaagct gctgggcaat
     7021 ttcttctaat ttttcattag cttgatccag ggtttggtta caaaaggcaa tggactcttc
     7081 caagcccaac agggcaggat aggttgattt ttctgcctgc agatcctttt gaggtgtctt
     7141 gccgatttcc tcaaaactag ctgtcacatc cagtacatca tctctgactt gaaaagcaag
     7201 tccaatcaat tcacccacag ttttcagctt cacctgcatt tcaggtgaca attcagctat
     7261 aatagctgcc gcttggaagg gataggctag taacttccca gtcttattgg catgaatagt
     7321 ctgaagttct tccaaagaca agtgctggtg ttcgccctcc atatccaaaa cttgccctgc
     7381 caccataccc agactacctg aagcaaggga taagttggca atcaagtcca ccttaatctg
     7441 acttggcaaa tctgcctgcg caatcaaggc atatgagtct aagaataagg catctccagc
     7501 caaaatggcc atagcttcac cgaatttctt gtgattggtt aaccgccctc ttcgataatc
     7561 gtcatcatcc atagcaggaa ggtcatcgtg aatcaagctc cctgtatgaa tcatctctaa
     7621 ggcagtagct acctgcgcgt gagcaggttt gatggtaacc tgcaaggctt ccagaacttc
     7681 taacaagaga aaaggccgaa tacgcttgcc accagcatga atagaataga gaacagactc
     7741 ccgtaaacta gaggcaaact gctggtctcc ataaaaatct tccaaagccg actcgacaag
     7801 agctaatttt tcttgctttt tcattcaaaa tcactttctg ttccgtcttc ttgcatgacc
     7861 ttgaccaagg tcttttcagc cttgtccagc gtagcttgga gctcttttga caagaccatg
     7921 cccttttgaa aggcagtaat cgcatcttcc agagcaattt caccattttc caaactttgg
     7981 acaatggttt ccagttctgc tagattttcc tcaaatttct tttgttttga catctttaac
     8041 ctctaattct acttgaccat ctcgcatcaa aagcgttact tggtcttttt tcttcaaact
     8101 ctcaaccgaa tctacaacgg actcttcttt tttgacaata gcataaccac gcgccacgat
     8161 tcggctagta tccaacatga gcaaagcttc cgaaagtcgc ttggcctcag caaccttggc
     8221 gtcataaact aacgccattt ggctacctaa gagcttgtcc aactgtccta aacggtcttg
     8281 atagcgttgg attttggtaa caggtgataa ttgtactaat tgatgagttc ttgcttgaac
     8341 taattgtttg ttatcagaaa tccgagttcg caaactttgt ttcaaacgca gttgcagttg
     8401 gtccaagcgt tgcaaataac cgtcatacaa gcgctcaggt tgtctaaaga taacagactg
     8461 actgcatttt ttcaaagcct cttgtttctt agatagaaca tttcggactg ccgttaccat
     8521 ccgtttttcc tgattttgca aatgagctaa tacatccaac ttggtcacag gtgttgccag
     8581 ttcagccgcc gctgttggcg ttgcagcgcg tcgatctgcc acaaaatctg ccaaggtcac
     8641 atccgtctca tgccccacac tagagataac tggcaaacga gattcaaaaa tagctcgtac
     8701 cacaatttct tcgttaaagg cccagagatc ctcaatagaa ccacctccac gaccaataat
     8761 gagcaaatcc aaatcgtccc gttgattagc acgcgcaata tttctagcaa tttcctccgc
     8821 agccccttca ccttgaacct tggtcggata aagaaggatg tcaacacctg ggaatcgcct
     8881 gctgacggtc gtgataatat ctcgaataac ggctccacta cggctggtta ctacaccaat
     8941 tctcttagaa aattggggca gagcttgctt gaagcgttct tgaaacaggc cttcttctgt
     9001 caattttttc ttaagttgtt caaactgaat cgcaagcgcc ccaaccccat caggctcagc
     9061 tttttcaatg atgatggagt agctaccact tggttcatag acctgtacac gcccaatcac
     9121 attgatcttc attccttctt ccaggtcaaa ccctaatttc tgataaatcc cagaccagat
     9181 ggtcgcttga ataactgcat ggtcatcctt tagggagaaa tattggtgag taggtcgttt
     9241 acgaaagttg gaaacttgac cagttaaata gacccgttcc aagtatgggt ctttatcgaa
     9301 tttcattttc agatacttgg tcaaagttgt taccgataaa tacttttcca tctccaccta
     9361 ctattcattt acttgctctt tcatgggtat tattatacca aaaatatgcc taaaaatctc
     9421 catttatgta ccattatgag ggaaaaatag aaaaaggagg caaggcctcc acatgtgatt
     9481 atttgctgtt tcgagcttct tccaaaatct ttgcaatctt ggtcgtcaac aggtcgatag
     9541 ccacggtatt gctaacccct tcaggaatga cgatatcagc ataacgctta gttgactcga
     9601 taaactggtg gtacattggt ttgaccacac ctaagtactg gttaataacg ctatcaaggc
     9661 tacggccacg ctcctccata tcacgcttga tacgacgaat aatgcgcaca tcgtcatccg
     9721 tatccacaaa aatcttgata tccatcaaat cgcgcagacg cttgtcctcc aagaccaaaa
     9781 taccctcaac gataaagaca tcttgaggtt cctgacgata ggtcttgcta ctccgtgtat
     9841 gctctgtata gtcgtaggtc gggatgtcca ccggacgccc tgccaacaat tccttaatct
     9901 gctcgatcat caagtctgta tcaaaggcaa aaggatggtc atagttggtt ttgacacgct
     9961 cttcaaaggt caaatgagac tgatccttgt agtatgaatc atgctcaatc atggaaatct
    10021 tttcatcagg aaaatgcgat aaaatggctc ttgaaacact ggttttacca ccaccagaac
    10081 cacctgtcac tccaataatg attggtctat tttgcatgct atcctccgtt attttatccg
    10141 tcgtctattc tatcacattt tttacaaaat ttatagtctc atcagcaaaa aacaccagag
    10201 tcttccctct gatgttcgac agttttaacg aaagccctgt agggtttgag caagcatctg
    10261 caagaaagcc agtctccctc tttcctggct aggagctttg gcaatccata aaccaaaatc
    10321 aatgacagac ttaggtgcct ggtaatgatg cgtcatgagg taaagtgaca acccttgact
    10381 caaattggcc atgaccgatt ggtatttttc atttctgtct aaattttgta tagcaagacg
    10441 aaacaggtga ctcaactcac tattttcatt tatttctttt tgttgaagaa gttgctccac
    10501 cctttctcga aactcatttc gcatcatgga attatcacac caaatcctgg gcctaagttc
    10561 ccatcagaac ctgtaatgga ctctaaatat ttatctgaaa gaattttaaa ttgcttcatt
    10621 tcacacctct aaatttctat atagattatt tgagtaccta caactcgcaa caattggaat
    10681 attataattc ccaaaaccat tctactatta gtatgggggt ttttcaagca attgttatct
    10741 atcacccgat ttttattcct aaacgatcta gctaaaaacc ttccttggct tatagagatt
    10801 gccccgtttt tctagaatgg ctaacaattt atcatcttca aaggcagcca gttctttgtc
    10861 cgtttggtct agctcaataa aacgaccaaa gcgaacttct gtagcctctt ctggagttag
    10921 gaaaactttg acaaggtcac ctgtcccaat ctctaaagga tggagaaaat ctaattgccc
    10981 agcctctact ttttcagcaa tttcctccaa ggcaagagcg tcttctaatt gtaagccagc
    11041 agcactagta cgagtcaaat gggacatatg agccgcataa ccaagctttt cacccaaatc
    11101 aactgacaaa gtacggatgt acgtcccttt actgcatttt acacgaaaag tgaatcgggc
    11161 aagttggcca tcataagaaa tcggacttgt tcgctcaaat tgataaatgg tcacctgacg
    11221 ttctggacgc tccacttcct gaccagcacg cgcatactca tagagcttgc gaccattaac
    11281 cttaactgcc gaatacatag ggggaatctg agtaataggc ccagtcaagc tagcaatcgc
    11341 ttcatcaaca agcttttcat ccaagagaga caaaacaggg gtttctgcga ccacttcccc
    11401 actagcatcc tcagtcttcg tggaatagcc cagagtgatt tccccctcat agatcttacc
    11461 ctcgtcctgc ataaactcga ccatgcgtgt cgccttgcca accgcaatcg gcaaaacacc
    11521 caccacatcc ggatccaagg ttccaccatg accaattttc ttggttccca aaatcttacg
    11581 cagtttaaaa accgcatcat gcgaggtcat tcctgcttcc ttttttaagt taataatacc
    11641 gttcattttt gctttctact cccccttcag tgcttcgaac ttcgctttca ttgttggatt
    11701 tttccgggtc aattttttaa cagagacatc ttccaatttg ttgttagcta aacggagttg
    11761 gttttcagat gtggtcagga atttcttaac ctcttccatg cgtttgatgg ccttgtcgat
    11821 ttcatcaata gcttttccaa agttagtcga agctgaatta tagttcttag caaaagctag
    11881 cttaaaggca tccaaatctt cctcaaaatg cgtaatgtca atattttgct cgcgaaccaa
    11941 ggccaactcc tgcttgtatt ttagggaatt tagcgccgca ttacgtaaga gaccaatcaa
    12001 ttggataaag aattgaggac gaacaacata cattttttca tactcgtgac tgacgtcaac
    12061 aatccctgtg ttaaagtagt cattatcagc ctcaagcatg gtcaccaaaa cggcatactc
    12121 acagttcttc tcccgacggt ccttgtccaa ttccttgtaa aaatctgcat tcttgtgctt
    12181 cttctctgtt ccgtccgctt cgtttttcat ctcaaacatg atagaaatga tttcaactcc
    12241 attttcatca cactcacgga agataaagtc ccctttagac ccacgcgaag agaccttgtt
    12301 atccttctca aagtaagcat ttggaaaggc gaaactacga accttgttaa actcactctc
    12361 tgcatactgt tctaggcttt ccccaatcgc ttttgtagat tgttgagcct taaaattctt
    12421 ataaaactcg acttgttcac tagctgcctt gagctgggct tcgtagtttt gcttaacaga
    12481 agccaaagat aattcatttt ccttttcctg caaaagtagt tggtttttaa cctgatcccg
    12541 ttctttttct aggtcagaaa gggtcttttg tagttgattt tcatgctcca aacgcaaggt
    12601 agccaactga ttttctaaga gctgtacttc cttgtcctta gccaagagag cctcatggct
    12661 tgtctgttca acctctttct tggccaattc tttttctgta tcaaagtttt ggatctgact
    12721 ctgtaattgc gcaatttctt gatccttctg agccagttta gtctgttgct cattcatggc
    12781 cttttgctca gccaaggcca gttcctgctt catcctatcg tgtagttcct tatcaaactc
    12841 tgccgttctc acttgggaca agagttcggc atactgactc tcatttactg taaagacttc
    12901 cccacagttg ggacatttga tttcgttcat atcgttcctc tttctagact tctttaacca
    12961 ttatatcatg cctgagggaa aatcaaaaac agtgagtcga agcccactgt ttatcttctt
    13021 ttactttaaa ttttttccaa ggccaagcgc aagtcttcaa tcaaatcttc tacattttca
    13081 agaccgattg acaaacgaat ttagtttggt gtgacacctg ctgcttctag gtctttttct
    13141 gacaattgac cgtgagtggt tgttgctgga tggacaacaa gcgatttagc atctgccgcg
    13201 tttgcaaggt cagaaaagat ttctaaatta tcaatgacct tgcgtgcttc ttcctcgcca
    13261 cctttgacgt ggaaggtaaa gattgaaccg acaccttttg gcaagtattt ctcagccaag
    13321 gcatgataag gactatctgc aagttttgga taatttacct tttctacctt aggatggttg
    13381 acaagaaaat caacaattgt ctcagcattt tgtacatggc gttccacacg aagtgaagag
    13441 gtttcaagtc tttgtagcaa gaggaaagca ttgaatggtg acaaggctgc acctgtatca
    13501 cgaagcaatt gaactcgaac agctataata aaggctgctg cacccacatc acgagtatag
    13561 ctcaaattgt ggcagcttgg accctcgtca acaaattgag ggaatttccc tgaagccgtc
    13621 cagtcaaaac gaccactatc gacaattatt cctccaatag ttgtaccatg cccaccgata
    13681 aacttagtca cagagtgaat ggcaatgtca acgccatgag agaagacgtt aatcaaataa
    13741 ggtgttgcaa aagtattgtc tgacacaagt gggatttgat gtttatgagc aatctctgcc
    13801 agtttttcca ggtctggaat attaatcaag gggttaccca aggtttcaat caagacaagc
    13861 ttggtattgt ctttgatagc tgcttctact tcctccaaat tatcaatatc gaaaaaggtt
    13921 gttgtgatac cataacgagg aaggggttct ttcaaaagat tgaaggttcc accgtaaata
    13981 gtcgaagcag ccactacatg gtcaccagca tgggcaatcg ccaaaatagt ataagtcact
    14041 gcagtcatac ctgatgctgt tgctagcgct tcaacaccac cttcaagggc agctgttgta
    14101 ggattggtga tacgagtata aatgttccct ggtttcctca aggcaaacag atcggcacct
    14161 tcctacgtgt catcaaaaac aaaaaatgtt gtttgataaa tcggcactgc acgagactta
    14221 gtagctggag ccacaacttg accagcatgt agttgtagag tttcaaattt aaaatcacaa
    14281 gtcataaggt gacctccata ttattttatt aaggatattg tagcaccttg agttatagtt
    14341 tacaaatatc agttttctat attttgatat aagaaatagc tattacctta ttttgaaaat
    14401 gaaaaaagca cgactcaatc gtgctcattt tcttaatcta cataagtatc ttcgttttta
    14461 ttgaggaagg catatggaag acccatcaag aggcctcctc cgataaagtt tccgatgaaa
    14521 gtcacacccc agtggcgaag catatttcca acaccgaagt tggcaattga atccgcagca
    14581 acactgaatt tcacaatcgc gaaagaagca aagttcgccg caatgtgctc gtttgttaag
    14641 aatacaaaca tgtaaatagc tgacaacaca agccaaagtt tggcaccacc atctttgacc
    14701 aaaataaatg acagaatcgc aatatttaca aaaatatttg ccaaaatcgc ctcaagcaag
    14761 accaattcat ttgagcggcc taacttcatc tcaacaacac ctgagatgaa actatcgtgt
    14821 gtcagattcg cataggctgc cgaatgagca aagccccacc ctgctatcaa ggctccgata
    14881 aggttgaaca aggtacagta tagtaaaatc tcagctgttt ttctccaaga gatttttttt
    14941 aagaaactac cagcagtcaa gaacatcatg tttgaagtga ccaactcggc attcaaaaaa
    15001 acaatgtagg ccaagcccca agcaaaaacg aatggaaaga ggaagcgtcc actacctggt
    15061 gcaattttat taatcaagtc agccccaact gcacctgcag cagtactgaa ggttaaaaat
    15121 gcacctgcga acatcgaacg aatcgcatac ttaaatttgc tttgactata aagactttct
    15181 ttcttattgc aagcaaattc aatctttgag ataaattccg aagaaaccat aataaactcc
    15241 taaatctttt tttcttgata attatatcac aaactttagg ttttaggaag cgttttctgt
    15301 atttcataaa agtttatagt agattgaaac tagaatagta cacctctact tctaaaacat
    15361 tgttagaaat cgatttgact gtcctgatcg atttgtccta ttcttatttc attttactat
    15421 atttttatga aaatcttaaa aaatcagtga aatcatggat ttcactgatt tgtattaata
    15481 aaattgttta tatggttgat tgaaagctgt taggatttca ttagatgttt gtgaataatc
    15541 ttttgtttct ttcaaatcac ctttgacaat aatacgttct gtagcagcaa ggtcttcaca
    15601 ggttactaat gtgatttcat tgaccccatc tctatcatca acttcatcaa cacgatccgg
    15661 tgtcacacgt ttgacttcac gtatttcata agtataaact ttatttttat cggttagata
    15721 aatcttcatg ccatttttag cattatctaa aggagaaaat aacattttat tagcattatc
    15781 aacaccaaag atatggtgac tagctagact ataatttcct tctcccatta cttgctcgcg
    15841 tttcattgta ccagctccgt agaagagatt aacattatca agtcctttaa aaatcggcaa
    15901 attcatttcc aattcaggaa ttgcaattcc cccaataact ggtaattttt gagcatccca
    15961 ttgagaagtt agaacagctt ccgaagagat agctttgaca gaatcaaagt caaaattgcc
    16021 ttctgtatcc tgattttctt ctaatttttc ttttgatacc tggctaactt gatacttatt
    16081 ggtattccag actatgaaaa tatttcgaat ttgagtatta aaaatcaaag ccagtgacag
    16141 taatatcaga aatcctgcta ggatatttgt cagcagattt tttcgcttgt ttttcttttt
    16201 attatttttt tgagacatta tgcttcacct tctgtttcgt tttctgtccc aacttcttct
    16261 ttttctgcca ccgcaaccgt tgtgaaagtc actatctgag catcttgatc caggcgcatt
    16321 actttaactc ccatagttgc acgtcctgtt tgtgaaatat tggcaagatt ggttcgaatc
    16381 atgacacctg tatcagtgat aatcatcaaa tcctcatccc cttgaacagt cataagaccg
    16441 gccagcaagc catttttttc ggtaatttta gctgtctgca ttcccttacc accacgacct
    16501 tttgttgggt attcagtagc gactgtacgc ttaccatatc ctttttctgt gataataaga
    16561 acctcatctt gatcagtaat caagctggca ccaacaactg tgtctccttc acgaaggtta
    16621 acacctttca caccagtggc gatacgactc ataccacgaa cggctgattg attaaagcga
    16681 actgcataac caaacttggt accaatgata atatccatat ctccttctgc caacaagaca
    16741 ttgattaact catcttcatc ctttaaattc agcgctttga gaccattttg acgaatattg
    16801 gcaaactcct taacactggt tctcttcaca ataccgtgac gggttgtaaa gaagagataa
    16861 gcatcatcac tgcgatcaga ctcaacattg ataaccgtct gaatactttc gtcttcatcc
    16921 aatttcaaga gattgactac tggtagccct ttggcagtcc gaccatactc aggaatttca
    16981 taacctttaa gacgatagac acgtcccttg tttgtgaaga agagcagatg atcatgggtg
    17041 ctagttgaca ctaactcacg aacaaagtca tcatctttca ctcccgttcc ttggacacca
    17101 cgacccccac gtttttgagc agtgaactcg tcctgatcca aacgcttaat gtagcctctg
    17161 ttagaaaggg taatcaagac atccgattct tcaatcaagt cctcatcctc gagactcaag
    17221 acctgtccaa tcatcaactc tgtacggcgc ttatcagaaa atttacgttt aacttcatcc
    17281 aattcgtctt tgataatttg agaaacacgt tcaggcttag caagaatatc tgctaaatcc
    17341 gcaatcagag ccaagaggtc atcatactca gattgaatct tatcgcgttc caaacctgtc
    17401 aaacgacgaa gacgcatatc aaggatagct tgactttgac gttcagaaag cttaaacttg
    17461 ctcatcaact cagcttgagc ttccgcatcc gtttcactag cacggatgat acgaatcact
    17521 tcgtcgatat ggtctagcgc aatcaagaga ccttctaaga tatgagcgcg cgcttccgct
    17581 ttttccttat caaaacgtgt acgacgaaca accacttctt tttggtgctc gatataagca
    17641 tccaaaatct gacgaagaga caaaattttc ggtataccat tttggatagc gagcatattg
    17701 aaaccaaaat tggtttgcat ttgggtcatt ttgaagaggt tattgagaat aacattggct
    17761 gaggcgtcgc gcttgacttc aataacaaat cgaacacctt cacggtttga ctcatcacgt
    17821 actg
//
