LOCUS       NZ_CMIW01000003        41173 bp    DNA     linear   CON 27-NOV-2024
DEFINITION  Streptococcus pneumoniae strain SMRU3003, whole genome shotgun
            sequence.
ACCESSION   NZ_CMIW01000003
VERSION     NZ_CMIW01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  AUTHORS   Informatics,Pathogen.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAR-2015) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001092805.1-RS_2024_11_27
            Annotation Date                   :: 11/27/2024 00:58:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,109
            Genes (coding)                    :: 1,938
            CDSs (with protein)               :: 1,938
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 171
            CDSs (without protein)            :: 171
            Pseudo Genes (ambiguous residues) :: 0 of 171
            Pseudo Genes (frameshifted)       :: 69 of 171
            Pseudo Genes (incomplete)         :: 100 of 171
            Pseudo Genes (internal stop)      :: 55 of 171
            Pseudo Genes (multiple problems)  :: 44 of 171
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:52:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 96432
            Orig. end                         :: 137605
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CMIW01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41173
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41173
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41173
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21173](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21173)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     misc_feature    complement(304..316)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.78"
                     /tool="antismash"
     gene            complement(846..1181)
                     /locus_tag="AD046_RS02760"
                     /old_locus_tag="ERS022513_00535"
     CDS             complement(846..1181)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /locus_tag="AD046_RS02760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00535"
                     /product="hypothetical protein"
                     /protein_id="WP_050115988.1"
                     /transl_table=11
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLYA
                     LFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRELG
                     KSKGGRH"
     gene            complement(1321..1656)
                     /locus_tag="AD046_RS02765"
                     /old_locus_tag="ERS022513_00536"
     CDS             complement(1321..1656)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /locus_tag="AD046_RS02765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00536"
                     /product="hypothetical protein"
                     /protein_id="WP_000400493.1"
                     /transl_table=11
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFYS
                     LFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQELG
                     KSKGGRH"
     misc_feature    complement(1678..1689)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.14"
                     /tool="antismash"
     gene            complement(1744..3054)
                     /gene="der"
                     /locus_tag="AD046_RS02770"
                     /old_locus_tag="ERS022513_00537"
     CDS             complement(1744..3054)
                     /EC_number="3.6.5.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="der"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /locus_tag="AD046_RS02770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00537"
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="WP_001207696.1"
                     /transl_table=11
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYAT
                     GEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVA
                     RKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENL
                     PNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDG
                     QEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGF
                     AHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLP
                     EMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFV
                     NEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(3068..3781)
                     /locus_tag="AD046_RS02775"
                     /old_locus_tag="ERS022513_00538"
     CDS             complement(3068..3781)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /locus_tag="AD046_RS02775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00538"
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="WP_050079693.1"
                     /sec_met_domain="PF00881 (E-value: 1.1e-22, bitscore: 74.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQS
                     YSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVEGL
                     LISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMALGVP
                     NQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGGRATTSWSQRLAEQFGQA
                     EPSSTRKNLEQKKLL"
     gene            complement(3778..4674)
                     /gene="dnaI"
                     /locus_tag="AD046_RS02780"
                     /old_locus_tag="ERS022513_00539"
     CDS             complement(3778..4674)
                     /codon_start=1
                     /gene="dnaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /locus_tag="AD046_RS02780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00539"
                     /product="primosomal protein DnaI"
                     /protein_id="WP_000446531.1"
                     /transl_table=11
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEELN
                     RSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAAIK
                     NRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGVGKS
                     FMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILDDIGA
                     EQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEARRVME
                     RIRYLAEETRLEGVNRR"
     gene            complement(4675..5844)
                     /locus_tag="AD046_RS02785"
                     /old_locus_tag="ERS022513_00540"
     CDS             complement(4675..5844)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /locus_tag="AD046_RS02785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00540"
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="WP_050102742.1"
                     /transl_table=11
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISFW
                     DNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQDFL
                     GHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKKVAN
                     DFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVISTKR
                     MREKIAQKPVSSDFSPKETTIIKEAKSKTALQFLSEIKQTRKGTITQTERDLLQQMAGL
                     GLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRERGQKAKT
                     QKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(5845..6318)
                     /gene="nrdR"
                     /locus_tag="AD046_RS02790"
                     /old_locus_tag="ERS022513_00541"
     CDS             complement(5845..6318)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /locus_tag="AD046_RS02790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00541"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_001203672.1"
                     /transl_table=11
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVE
                     ERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQ
                     SEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            6458..6823
                     /locus_tag="AD046_RS02795"
                     /old_locus_tag="ERS022513_00542"
     CDS             6458..6823
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /locus_tag="AD046_RS02795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00542"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_000119153.1"
                     /transl_table=11
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEAG
                     VNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTHFG
                     YEKEELPGVVSDYIKGV"
     gene            6828..7523
                     /locus_tag="AD046_RS02800"
                     /old_locus_tag="ERS022513_00543"
     CDS             6828..7523
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /locus_tag="AD046_RS02800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00543"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000054201.1"
                     /transl_table=11
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTTL
                     IKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYKDF
                     NLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPAARA
                     YILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESGESID
                     QLFRQEFKA"
     gene            7540..8307
                     /locus_tag="AD046_RS02805"
                     /old_locus_tag="ERS022513_00544"
     CDS             7540..8307
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /locus_tag="AD046_RS02805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00544"
                     /product="membrane protein"
                     /protein_id="WP_000498748.1"
                     /transl_table=11
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQE
                     SQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITAKL
                     IGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLNTIS
                     GILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGLNDHF
                     YMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     misc_feature    7566..7581
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            complement(8660..9859)
                     /locus_tag="AD046_RS02810"
                     /old_locus_tag="ERS022513_00545"
     CDS             complement(8660..9859)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /locus_tag="AD046_RS02810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00545"
                     /product="ABC transporter permease"
                     /protein_id="WP_001245352.1"
                     /transl_table=11
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGSS
                     MAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSVLK
                     AVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEAKEN
                     KKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYARMMA
                     LFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISLFMYVV
                     LAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPFISTFFM
                     PFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTFKRALSYK
                     "
     gene            complement(9856..10749)
                     /locus_tag="AD046_RS02815"
                     /old_locus_tag="ERS022513_00546"
     CDS             complement(9856..10749)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /locus_tag="AD046_RS02815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00546"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000895292.1"
                     /transl_table=11
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIFH
                     SILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDAKE
                     VKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLDPVN
                     TELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQYGKT
                     RLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIATFDQQ
                     APTIDEIFKLESGVEV"
     gene            10872..11063
                     /locus_tag="AD046_RS12795"
                     /old_locus_tag="ERS022513_00547"
     CDS             10872..11063
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AD046_RS12795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ERS022513_00547"
                     /product="hypothetical protein"
                     /protein_id="WP_050102753.1"
                     /transl_table=11
                     /translation="MKSKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVSN
                     YIYGKAKLTWFEEIFEEY"
     misc_feature    11445..11461
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.07"
                     /tool="antismash"
     gene            <11456..11644
                     /locus_tag="AD046_RS12130"
                     /pseudo=""
     CDS             <11456..11644
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /locus_tag="AD046_RS12130"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS30 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GSNENHNRLIHR"
     gene            12059..12676
                     /locus_tag="AD046_RS02825"
                     /old_locus_tag="ERS022513_00548"
     CDS             12059..12676
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /locus_tag="AD046_RS02825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00548"
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="WP_000076185.1"
                     /transl_table=11
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQSK
                     ETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGIVI
                     GCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADFLCM
                     LAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(12996..13883)
                     /gene="scrK"
                     /locus_tag="AD046_RS02830"
                     /old_locus_tag="ERS022513_00549"
     CDS             complement(12996..13883)
                     /EC_number="2.7.1.4"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008865 - fructokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scrK"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /locus_tag="AD046_RS02830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00549"
                     /product="fructokinase ScrK"
                     /protein_id="WP_000164313.1"
                     /transl_table=11
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKTI
                     EFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPMYF
                     TTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHYYVA
                     RHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYIAQAA
                     VNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAVAGNGS
                     ATLGNFVLAKEVSK"
     gene            complement(14032..15915)
                     /locus_tag="AD046_RS02835"
                     /old_locus_tag="ERS022513_00550"
     CDS             complement(14032..15915)
                     /EC_number="2.7.1.211"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /locus_tag="AD046_RS02835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00550"
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="WP_001861964.1"
                     /transl_table=11
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVI
                     ENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQRA
                     IRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVV
                     WSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPA
                     FIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATK
                     AILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGA
                     ATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLA
                     SILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAA
                     AKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGV
                     VYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKVAQGNKVKAGD
                     VLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIEVKI"
     gene            16292..17746
                     /locus_tag="AD046_RS02845"
                     /old_locus_tag="ERS022513_00551"
     CDS             16292..17746
                     /EC_number="3.2.1.26"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /locus_tag="AD046_RS02845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00551"
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="WP_050102741.1"
                     /transl_table=11
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGLL
                     NDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDSHG
                     AYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPADSTD
                     HFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRTAYMM
                     ECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQLQNMD
                     YGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDDKLYQYP
                     VAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSINFDLVNGQ
                     VTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVFSGRVFPHA
                     DQNSILIKSGNPTGTYYELDYGRKTN"
     gene            17727..18692
                     /locus_tag="AD046_RS02850"
                     /old_locus_tag="ERS022513_00552"
     CDS             17727..18692
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /locus_tag="AD046_RS02850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00552"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_000226001.1"
                     /transl_table=11
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMRELG
                     YKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDSEK
                     EREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAGGVL
                     AAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKEMEIK
                     NILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQLATIK
                     QPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(18727..20001)
                     /locus_tag="AD046_RS02855"
                     /old_locus_tag="ERS022513_00553"
     CDS             complement(18727..20001)
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /locus_tag="AD046_RS02855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00553"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_000704388.1"
                     /transl_table=11
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTVA
                     DQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFTAQ
                     VHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVEQIK
                     GEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSLVTAS
                     CRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIATGNDWR
                     AIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPRVALSHD
                     LLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGASESEVAP
                     LVERLISDKTFNLETAQRYLENLRS"
     gene            complement(20001..21173)
                     /locus_tag="AD046_RS02860"
                     /old_locus_tag="ERS022513_00554"
     CDS             complement(20001..21173)
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /locus_tag="AD046_RS02860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00554"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_000151957.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 5.3e-09,
                     bitscore: 29.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSIA
                     PLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFARS
                     FEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAMLIT
                     QNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQKRYQL
                     TLDDFAAVCFHLPYPKLALKGLKKIMDKNLPQEKKDLLQKHFDQSILYSQKVGNIYTGS
                     LFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLNKLNQRT
                     ALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(21304..21552)
                     /locus_tag="AD046_RS02865"
                     /old_locus_tag="ERS022513_00555"
     CDS             complement(21304..21552)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /locus_tag="AD046_RS02865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00555"
                     /product="hypothetical protein"
                     /protein_id="WP_001813143.1"
                     /transl_table=11
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFYQ
                     KFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(21620..>21919)
                     /locus_tag="AD046_RS02870"
                     /old_locus_tag="ERS022513_00556"
                     /pseudo=""
     CDS             complement(21620..>21919)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="AD046_RS02870"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00556"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LEMRNIGQAGKILADSGYQGLMKIYPQAQTSRKSSKLKPLTAEDK
                     ACNHALSKERSKVENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     misc_feature    21887..21902
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.17"
                     /tool="antismash"
     gene            complement(21956..22189)
                     /locus_tag="AD046_RS02875"
                     /old_locus_tag="ERS022513_00557"
     CDS             complement(21956..22189)
                     /NRPS_PKS="Domain: PP-binding (8-72). E-value: 3e-11.
                     Score: 35.5. Matches aSDomain:
                     nrpspksdomains_AD046_RS02875_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /locus_tag="AD046_RS02875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00557"
                     /product="acyl carrier protein"
                     /protein_id="WP_000136447.1"
                     /sec_met_domain="PP-binding (E-value: 1.5e-11, bitscore:
                     38.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 5.5e-05, bitscore:
                     17.1, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEFI
                     LTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     aSDomain        complement(21974..22165)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AD046_RS02875_PP-binding.1"
                     /evalue="3.00E-11"
                     /label="AD046_RS02875_PP-binding.1"
                     /locus_tag="AD046_RS02875"
                     /protein_end="72"
                     /protein_start="8"
                     /score="35.5"
                     /tool="antismash"
                     /translation="RIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEFILTLEDEFS
                     IEISDEEIDQLQNVGDVVK"
     gene            complement(22195..>23124)
                     /gene="plsX"
                     /locus_tag="AD046_RS02880"
                     /old_locus_tag="ERS022513_00558"
                     /pseudo=""
     CDS             complement(22195..>23124)
                     /GO_function="GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="plsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /locus_tag="AD046_RS02880"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00558"
                     /product="phosphate acyltransferase PlsX"
                     /pseudo=""
                     /transl_table=11
                     /translation="VNQALSDFSDIEVQLYGDEAKIKQYLTATERVSIIHTDEKIDSDD
                     EPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTGALLAAGFFIVGRIKNIDRPGLMS
                     TLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSFYAKNVRGIAQPRVGLLNNGTESSK
                     GDPLRKETYELLAADESLNFIGNVEARDLMNGVADVVVADGFTGNAVLKSIEGTAMGIM
                     GLLKTAITGGGLRAKLGALLLKDSLRGLKKQLNYSDVGGAVLFGVKAPVVKTHGSSDAK
                     AVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(<23115..>23573)
                     /locus_tag="AD046_RS11275"
                     /pseudo=""
     CDS             complement(<23115..23573)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="AD046_RS11275"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVREYRTYEQIAADFGIHESNLLRRSQWVEVTLVQSGFTISRTPL
                     SSEDTVMIDATEVQINRPKKRISE"
     misc_feature    23602..23616
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 27.71"
                     /tool="antismash"
     gene            complement(23635..24084)
                     /locus_tag="AD046_RS02895"
                     /old_locus_tag="ERS022513_00560"
     CDS             complement(23635..24084)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /locus_tag="AD046_RS02895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00560"
                     /product="threonine/serine exporter family protein"
                     /protein_id="WP_000176924.1"
                     /transl_table=11
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLIY
                     LLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTAFF
                     VTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(24086..24844)
                     /locus_tag="AD046_RS02900"
                     /old_locus_tag="ERS022513_00561"
     CDS             complement(24086..24844)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /locus_tag="AD046_RS02900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00561"
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="WP_000392880.1"
                     /transl_table=11
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGIV
                     DCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAFKQ
                     LTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVEKFI
                     RIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDIMTNH
                     INSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(24959..26938)
                     /gene="stkP"
                     /locus_tag="AD046_RS02905"
                     /old_locus_tag="ERS022513_00562"
     CDS             complement(24959..26938)
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /gene="stkP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /locus_tag="AD046_RS02905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00562"
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="WP_000614540.1"
                     /sec_met_domain="Pkinase (E-value: 3.7e-57, bitscore:
                     187.3, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLR
                     TNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYIKE
                     HYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAE
                     TSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIAL
                     QHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNES
                     KLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQAPKKHR
                     FKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKT
                     EASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEK
                     KVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIG
                     RNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVSKPTQIVLTVA
                     KKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAG
                     EKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(26935..27675)
                     /locus_tag="AD046_RS02910"
                     /old_locus_tag="ERS022513_00563"
     CDS             complement(26935..27675)
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /locus_tag="AD046_RS02910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00563"
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="WP_000406248.1"
                     /transl_table=11
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAGN
                     IASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLEVL
                     AIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKNIIT
                     QSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTETLVR
                     FANNAGGLDNITVALVSMNEEDEE"
     gene            complement(27690..29003)
                     /gene="rsmB"
                     /locus_tag="AD046_RS02915"
                     /old_locus_tag="ERS022513_00564"
     CDS             complement(27690..29003)
                     /EC_number="2.1.1.176"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001510 - RNA methylation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /locus_tag="AD046_RS02915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00564"
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="WP_001814363.1"
                     /transl_table=11
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKGL
                     VTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVNEA
                     VELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKEEYG
                     EERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAGHNLF
                     ADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHK
                     LDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRRKPDIKY
                     NKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQ
                     VKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(28996..29931)
                     /gene="fmt"
                     /locus_tag="AD046_RS02920"
                     /old_locus_tag="ERS022513_00565"
     CDS             complement(28996..29931)
                     /EC_number="2.1.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /gene="fmt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /locus_tag="AD046_RS02920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00565"
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="WP_000163693.1"
                     /transl_table=11
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVI
                     QETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMDFA
                     VNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDNVG
                     TLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLF
                     NQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQ
                     VQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(29944..32340)
                     /locus_tag="AD046_RS02925"
                     /old_locus_tag="ERS022513_00566"
     CDS             complement(29944..32340)
                     /EC_number="3.6.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /locus_tag="AD046_RS02925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00566"
                     /product="primosomal protein N'"
                     /protein_id="WP_001162113.1"
                     /transl_table=11
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKGN
                     RLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKISIL
                     KAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRKGLL
                     GLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLASLLES
                     YSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSSIGSSQ
                     PPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFGDKVAIL
                     HSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYKQDSNPRY
                     HAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLATIPEVQVID
                     FRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECGTVDTCPNCD
                     ISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDELAELFPQARIL
                     RMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGVLNADTALNLPD
                     FRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDYEGFYAYEMGIRR
                     QLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILGPTPKPIARTHNLY
                     HYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL"
     gene            complement(32406..32720)
                     /gene="rpoZ"
                     /locus_tag="AD046_RS02930"
                     /old_locus_tag="ERS022513_00567"
     CDS             complement(32406..32720)
                     /EC_number="2.7.7.6"
                     /GO_function="GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rpoZ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /locus_tag="AD046_RS02930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00567"
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="WP_000979235.1"
                     /transl_table=11
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSEK
                     STLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGEKI
                     "
     gene            complement(32745..33371)
                     /gene="gmk"
                     /locus_tag="AD046_RS02935"
                     /old_locus_tag="ERS022513_00568"
     CDS             complement(32745..33371)
                     /EC_number="2.7.4.8"
                     /GO_function="GO:0004385 - guanylate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="gmk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /locus_tag="AD046_RS02935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00568"
                     /product="guanylate kinase"
                     /protein_id="WP_000775037.1"
                     /transl_table=11
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQR
                     PGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIE
                     VQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALMREY
                     DYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(33501..35114)
                     /locus_tag="AD046_RS02940"
                     /old_locus_tag="ERS022513_00569"
     CDS             complement(33501..35114)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /locus_tag="AD046_RS02940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00569"
                     /product="ribonuclease Y"
                     /protein_id="WP_000404945.1"
                     /transl_table=11
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQE
                     ATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELKQI
                     ESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAELER
                     IGALSQAEARDIILVQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRIAGEY
                     VAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFDPIRRE
                     IARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHPDLMKIM
                     GRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAIDHEVEGSH
                     VEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGARSESLESY
                     IKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKVRKKIENNLD
                     YPGNIKVTVIRELRAVDYAK"
     gene            complement(35305..35559)
                     /locus_tag="AD046_RS02945"
                     /old_locus_tag="ERS022513_00570"
     CDS             complement(35305..35559)
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /locus_tag="AD046_RS02945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00570"
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_050102637.1"
                     /transl_table=11
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQREPFTGIGKP
                     EPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(35563..35817)
                     /locus_tag="AD046_RS02950"
                     /old_locus_tag="ERS022513_00571"
     CDS             complement(35563..35817)
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0097351 - toxin sequestering activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /locus_tag="AD046_RS02950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00571"
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_000388572.1"
                     /transl_table=11
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKSE
                     WDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(36055..37152)
                     /locus_tag="AD046_RS02955"
                     /old_locus_tag="ERS022513_00572"
     CDS             complement(36055..37152)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /locus_tag="AD046_RS02955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00572"
                     /product="nucleotidyltransferase"
                     /protein_id="WP_050102638.1"
                     /transl_table=11
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAIV
                     DKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRDYQ
                     KIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYAKAV
                     AGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQVSKVI
                     WEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRYTKARV
                     RRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDAMTQKAD
                     QIYQLGNPSIAEQNFGRVPIRIETN"
     gene            complement(37162..37902)
                     /locus_tag="AD046_RS02960"
                     /old_locus_tag="ERS022513_00573"
     CDS             complement(37162..37902)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /locus_tag="AD046_RS02960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00573"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000257070.1"
                     /transl_table=11
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELAC
                     GTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYDFV
                     TCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENAEDF
                     AMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQAGFKSF
                     KLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(38222..38575)
                     /gene="rsfS"
                     /locus_tag="AD046_RS02965"
                     /old_locus_tag="ERS022513_00574"
     CDS             complement(38222..38575)
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsfS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /locus_tag="AD046_RS02965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00574"
                     /product="ribosome silencing factor"
                     /protein_id="WP_001003001.1"
                     /transl_table=11
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMNS
                     RQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEKLW
                     HEANSVDISEALA"
     gene            complement(38588..39088)
                     /locus_tag="AD046_RS02970"
                     /old_locus_tag="ERS022513_00575"
     CDS             complement(38588..39088)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /locus_tag="AD046_RS02970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00575"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_000844707.1"
                     /transl_table=11
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIYV
                     QHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLCGM
                     QTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVLDYK
                     HIF"
     gene            complement(39089..39682)
                     /gene="yqeK"
                     /locus_tag="AD046_RS02975"
                     /old_locus_tag="ERS022513_00576"
     CDS             complement(39089..39682)
                     /EC_number="3.6.1.41"
                     /codon_start=1
                     /gene="yqeK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /locus_tag="AD046_RS02975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00576"
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="WP_000121651.1"
                     /transl_table=11
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRFG
                     VDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQEDLD
                     LHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKAVAY
                     ETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(39682..40311)
                     /locus_tag="AD046_RS02980"
                     /old_locus_tag="ERS022513_00577"
     CDS             complement(39682..40311)
                     /EC_number="2.7.7.18"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /locus_tag="AD046_RS02980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00577"
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="WP_000151313.1"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-37,
                     bitscore: 123.1, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVAD
                     QVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERKGI
                     SYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKVGTS
                     YPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(40363..40674)
                     /gene="yhbY"
                     /locus_tag="AD046_RS02985"
                     /old_locus_tag="ERS022513_00578"
     CDS             complement(40363..40674)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="yhbY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /locus_tag="AD046_RS02985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS022513_00578"
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="WP_000060169.1"
                     /transl_table=11
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDARE
                     LIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKEI"
     misc_feature    complement(40715..40729)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 21.39"
                     /tool="antismash"
     misc_feature    complement(40724..40738)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.12"
                     /tool="antismash"
     misc_feature    complement(40779..40797)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.54"
                     /tool="antismash"
ORIGIN
        1 aaggcaaggc actatagagc agcatagaac caagccaaag aaatatcaaa taggtgattg
       61 ccgaacgagt cacattcccc acataatcaa ctatttgtaa aaaatagatt gcattgatga
      121 aaataccgat tagtaggaca caagtaaaga acaaatagct ttttatctct ccatctagga
      181 gtctttgtaa accactccca tcagaaaata gagaattcca ttcaagagga gaaaaagtcc
      241 caaagaaata ggttataatt gcaattatca gcacagtcac taaatatatc aaacaaggga
      301 tacttgcaac ttgcaaagtc aactttcttt ttaacccttg atagctcact tctcttccaa
      361 tactcaatcg taaaacttta tttttcagct caatatattg aaaacctagc aaaacaatga
      421 tgattggaat aataaatgat tgataaaaac ctagattgaa ctggagaata cgaaaatcta
      481 atgctgattt taataagtca tttttaattg cttgtccatc gaatttagct agatcgggcg
      541 catgaatatc aaaaaagaaa taagtcatca aaacatcacg ataaaccaaa gcaagaaaaa
      601 gcaaagtaag taagatataa acaaatttat gccttgccaa agttaagaga ggaatcttca
      661 taagccacct cctacaaata gaaagtaata taatactcaa tgaaaatcaa agagcaaact
      721 aggaaactag ccgcaagttg ctcaaagcac tgctttgagg ttgtagataa gactgacgaa
      781 gtcagttaca tatataatcc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
      841 ataaatcaat gccttccgcc tttagacttc cctagttccc gcctcaagcg aatcattttt
      901 ttgaaaaaga cataggctaa ccaatcacta gcaaaagcga taagtagtaa taatagccaa
      961 ataccccata acttgatatc tgtcaaattt ctcaagacga tattgaaaaa cagaactgaa
     1021 aaaactgtcc aagcaaggct aaaaagagca tagagggtga tgtaaatcca gtaaaaatag
     1081 taaaaaattg ggaaaatctt actatctctg tttgcctttt caatccagct gaaaaagtaa
     1141 aaacagggta ataagattat cattttaaac aagtattcca tcacaaacct cctcttttaa
     1201 attgttttct ttagtttcgt tctattaaat gttattacca atataaacct tggaatagcg
     1261 tgtaataaat gattttagag gtaccataag ccacctccta caaatagaaa ccgatataaa
     1321 tcaatgcctt ccacccttag acttccctag ttcctgtctc aagcgaaaca tttctttgaa
     1381 acaggaataa gttaaccaat tcataccaat agctagcaga ataaaaagaa accaaatgcc
     1441 ccataacttg atatctgtca catttctcaa gacggtattg aaaaacagaa ctgaaacaac
     1501 tgtccaagca aggctaaaaa gagaatagaa ggggatgtaa aaccagtaaa aataataaaa
     1561 aattggaaaa aacttactat ttctgttggc cttttcaatc cagttatcaa aataaaagta
     1621 cggtgctaaa agtaagaatt taaacaaatg ttccatcacc gacatccccc ttcttttgat
     1681 agcgttttct atcattttat tatatcaaaa aaatccggaa ctgtcattcc agattctaat
     1741 tttttatttg cgttttcttg cgatgagatg aatcggtgtt ccctcaaaaa caaaggcctt
     1801 gcggatttga ttttccaaga aacgcaggta agaaaagtgc atgagttctt cttcattgac
     1861 aaagatgaca aaggttggtg gtttggttgc cacttgggtc gcatagaaaa tcttgagacg
     1921 ttttcctttg tctgtcggtg ttgggttgat ggcaatggca tccatgatga catcgttcaa
     1981 gacagctgat ggaatacgtg tattttgact ttcgctgatt tgcttaatca tctcaggaag
     2041 tttgtggaga cgttgcttgg ttaaagctga tacaaagata atcggtgcgt aaggcaggta
     2101 ttggaactgc tcacggatat cttcttccca gtttttcata gtgtggttat ctttttcaag
     2161 cgtatcccac ttgttgacca cgataatcat ccctttacca gcttcatggg caaatcctgc
     2221 gatacgcttg tcgtactcac gaatgccttc ttccgcattg atgaccatca agaccacatc
     2281 tgaacggtca atagcacgca tggcacgcat aacagagtat ttctcagtat tttcataaac
     2341 cttaccagac ttacgcatac cagccgtatc aatcatggta aactcttgac catctgtatc
     2401 tgtaaagtgg gtatcaatag cgtcacgagt tgttccagca acaggactgg caatgacacg
     2461 gtcttctccc aagatagcat taatcaagct tgattttcca acgttaggac gaccaatcaa
     2521 gctaaactta atgacatctg gattttcttc ttcatattca tttggaaggt tttccacaat
     2581 cgcatctagt acatcccctg taccgatacc atggacagat gagataggca gtggttcacc
     2641 caaaccgaga gcatagaaat catagatatc atttctcatc tcagggttat ccaccttgtt
     2701 gactgcgagg ataactggtt tgtgggtctt ataaagcttg cgggctacgt attcgtctgc
     2761 atcggtaatt ccttccttac cggacacgac aaagacgata acatctgctt cttccatggc
     2821 aatttctgcc tggtgcttga tttgttccat gaaaggagca tcgacatcat caattcctcc
     2881 tgtatcaatc atgctaaaag aacgattgag ccactcaccc gttgcataaa tacggtcacg
     2941 tgtcactcct tcgacatctt ctacaatgga gattcgctca ccagcgatcc gattaaatag
     3001 ggttgatttc ccaacattgg gacgtcctac aatggcaata gttggtaggg ccataatttc
     3061 tcactttcta caataatttc ttctgttcaa gattttttct agttgagctt ggttcagctt
     3121 gaccaaactg ttctgctagg cgctgactcc agcttgtggt cgcacgcccc ccagcatagt
     3181 cagcctgaac acggtcataa gcttggattg cctcagttga ctgttcttgg tattcttcct
     3241 caaagacaac attctctagt ggcagtctcg gtttcatatc atgatgttga tttggcacac
     3301 ccagtgccat cccaaagaca gaataggtgt agtcaggtag gttaaagagc tctgccactt
     3361 cttcagactt gtatcgaacc aaaccgataa tcacaccacc atagcccaag ctttcagctg
     3421 ccaacaaggc gttttgtcca gcaagagctg catcgaccga actaatcaag agaccttcca
     3481 caccttgggg ttggaaggtg tcggtatgaa gtcgggctcc cttttctgct cggttcaaat
     3541 ctccgacaaa gagaaggaaa acagcagact ggcgaatggc ttcttgaggt accaattcat
     3601 acaaggcatc tttcttctct tgacttcgta ccacaatcac agagtaggat tggaaattct
     3661 tccaagatga tgccatctgg gctgctgtca aaatctcatt taagtctact tggggaattt
     3721 cttgctcttt aaacctgcgc actgaagtat gagccttcat caatttaatg gtttctgtca
     3781 tcgacggttt actccttcta aacgagtctc ctcagccaaa taacggatgc gttccatgac
     3841 ccgtctggct tcccaggttt cgtcatttcc atgtttcact ttcgcaaaat gcttctccaa
     3901 atcttcaaag ttgaagttgg atgtgaaaaa ggtcggtaaa ttttcctgca tccgatattg
     3961 gagaatgacc tgcaggattt cgtcacgcac ccaaacggtt gattgctcgg cgccaatatc
     4021 atctaaaatc aggacctcag acagcttaat ctcatccacc aaggtcttaa cattgccatc
     4081 actgatagca tttttgacat caatgacaaa gctaggatag tggaggagag tggatgaaac
     4141 accacgtttt tctgataaat catgagctaa ggccgccacc atgaaacttt tacccacacc
     4201 aaagtctcca tataagtaaa gaccttttcg aatagctgga tattgctcca cgaaggctag
     4261 tagcttttca aaaactggta agcgccccaa atcatccaag tcaacttgag ccaaactagc
     4321 tttcttgaga ctggctggta gattgattaa cttgagacgg ttcttaatag ccgcttcttt
     4381 ttcagccgcg attagctcag gagtttcttc atatgaaaca tctgcatagc catgattctt
     4441 aaccaaaatc ggcttgtagc ctttggcaat ataatccgta tccccacgga gaaacttgtc
     4501 acgctcggtg atgtactgat taaacttgga gatactgcga tttaattcct ctggagtcaa
     4561 ggattcttgc tggataaaag ccgcaacatc agggtccttc atgattttct ggaccaaatc
     4621 ttgataataa aaacggctgg gttgacgttt gagtacgtct ccgacacttt ccatctaatc
     4681 tcctcctttt tctaatcgag ctaatagttc ttgcttctta cgttctagtt ccagacgagt
     4741 ttcctcgctg gtttcattct tatattcagg attactccat ttaggaacat tggtttttac
     4801 tggggcagtc tgattctgtt tttgtgtttt tgctttctgc cctcgctcac gaattcgtaa
     4861 aacggcctct tctgccgaat gaatcttttg ataggcatag tcattggcta ccttcatggc
     4921 atatttctca ttgatatttg ccgaatccac cttattaaag gtcaataaga gaataatatt
     4981 gatgacttcg tccagtaagc ccaagccagc catctgttgc aagaggtctc tttctgtttg
     5041 ggtaatggtt cccttgcgtg tttgcttgat ttctgataag aactgcaggg cagttttact
     5101 tttagcttcc ttgataatgg ttgtttcctt aggactaaag tccgaggaaa ctggtttttg
     5161 agcaattttt tcccgcatgc gtttggttga aataacctgg gaaacagctg ttgacttggc
     5221 caattgatag gtctcaaacc aagtccactt cttctcctca gcaatagcaa acaagttcaa
     5281 gacatcagac tgctcatccg caaaacgaag tccatctcga gccatcagct gacgaaaatg
     5341 atccaagtca aaatcattgg ccactttctt cttgagacca aggtcttctt gactgcctag
     5401 ttctgccaat tctggaaaga cttgattgag tgagacaggt atttcttcac catcagcact
     5461 ttcaactttc aaatcctcca cagctacatc gccaatcttt ttctctaaga gtctgcgata
     5521 aacaggatgc cccaagaagt cttgactaga tagaggagca tggagggcta gctgataaac
     5581 atcccccttt tgatagagag tcaagagatt aaaagcagat aagattttca atgattttat
     5641 cagtctatcc atcccaaagt tgagatgatt gaggatactt gaaaaaagat attcctttct
     5701 accattatcc caaaaactaa tcgtataaag ataaaggctc agtgcctcct gaccgataat
     5761 cgggaggtag cactgtacca gagatgaggt atcttgcgac acccgattat tctttagata
     5821 agaaaaacgg tcaattggct tcatttatct ttcctttttc tttttagagg actgggtgat
     5881 ttgttggagc aagctctcta actcactgac atccttaaaa ctacgataga cactagcaaa
     5941 acgtacatag gtaatctcgt ccaattcagc caactcctcc atgacgagtg aaccaatgtc
     6001 ctcactttga atttcatttt catttcgacc acggagtttc tgttcgatac gattgactac
     6061 catgttgatt tcatcacttg acacaggacg tttctgggct gagcggataa tcccattaaa
     6121 gattttatct ctggagaatt gttcccgtgt gccatctttt ttaacaacca ctaaggttct
     6181 ttcttctact cgttcgtagg ttgtaaaacg gtgttggcat tcgtcgcact cacgtcttct
     6241 acgaatggtg ttcccttctt ctgcttggcg actatcgata acacttgact tggtagcccc
     6301 acattttgga caacgcatcc tttccctcct tatcgttttc ttttcattat accatttttt
     6361 aagcgattcc caaaacaatt cttctttttg cttgacaagt tttttgtttt gttgtattat
     6421 ttaattaaga caatagggta aaagaaagga gactaagatg tcctggacat ttgacaacaa
     6481 aaaacccatc tatttacaga ttatggagaa aatcaagctt cagattgttt cccatacact
     6541 ggaacccaat caacaacttc caaccgtgag ggagctagct agcgaggctg gtgtcaatcc
     6601 caataccatc caaagagcct tatcagacct tgaacgagaa ggatttgtct atagcaagcg
     6661 aacaactgga cgatttgtga ctaaggataa ggagctaatc gcccagtcac gcaaacaatt
     6721 atcagaagaa gaattggaac acttcgtttc ctccatgacc cattttggct atgaaaaaga
     6781 agaactacca ggcgtagtca gtgattatat taaaggagtt taagcctatg tcattactag
     6841 catttgaaaa tgtatccaaa tcatatggag caacaccagc ccttgaaaat gtttctcttg
     6901 acattccagc tggaaaaatt gtcggccttc ttgggccaaa cggctcagga aaaacaaccc
     6961 tgattaaact aattaatggc ctcttacaac cagatcaagg acgtgtcctc atcaacgaca
     7021 tggacccaag cccagcaacc aaggccgttg tagcttattt gcctgatacg acttatctca
     7081 atgagcaaat gaaggtcaaa gaagccctaa cctacttcaa gaccttctat aaagatttca
     7141 atcttgaacg cgctcatcat ctacttgcag acctgggcat tgatgaaaat agtcgtctca
     7201 agaaactatc aaaaggaaac aaagaaaagg ttcaactgat tttggttatg agccgtgatg
     7261 ctcgtctcta tgttttggat gaacccattg gtggggtgga tccagcagcc cgtgcttata
     7321 tcctcaatac cattatcaac aactactcac caacttctac cgttttgatt tctacccact
     7381 tgatttctga tatcgagcca atcttggatg aaattgtctt cctaaaagac ggaaaagtcg
     7441 tccgtcaagg aaatgtagat gatattcgct acgagtcagg tgaatccatt gaccaactct
     7501 tccgtcagga atttaaggcc taagcaaagg agattattta tgttttggaa tttagttcac
     7561 tacgaattta aaaatgttaa caagtggtat ttagccctct acgcagccgt gctagtcctt
     7621 tctgccctca tcggaataca gacacaaggc tttaaaaatc taccttacca agaaagtcag
     7681 gctactatgc tactttttct agctacagtc tttggtggct tgatgcttac acttgcgatt
     7741 tcaaccattt tcttgattat taaacgcttc aaaggtagtg tctacgaccg acaaggctat
     7801 ctgactttga ccttgccagt ttctgaacac catatcatca cagccaaact aatcggtgcc
     7861 tttatctggt cattgattag caccgctgta ttggctctaa gtgctgttat tattctggct
     7921 ttaacagctc cagaatggat tcctctttct tatgtgatta catttgtaga aacacatctc
     7981 cctcagatct ttcttacagg tatatccttc ctactaaata ctatttcagg aatcctctgc
     8041 atctacctgg ctatttccat tggacagctt ttcaatgaat accgtacagc actcgctgtt
     8101 gcagtctaca ttggtatcca aatcgtcatc ggatttattg aacttttctt caatcttagt
     8161 tctaatttct atgtcaattc actggtagga ctcaatgacc atttctatat gggagcaggt
     8221 atagccattg ttgaagaact catattcata gctatctttt atctcggaac ctactacatc
     8281 ttgagaaata aggttaattt gctttaaata atttttacct agatatgtaa catactcata
     8341 gaacaaaaga gaccaggcaa aaagtcttta caattagaaa acgcatagta tcaagtgtta
     8401 aaaatccttg atattatgcg ttttttgtga gctgacttat ttcctttcac tatatcgcaa
     8461 aatgaaataa gaacggaacg atgggatttt ggaattcaaa tcaatttata agaatgtttt
     8521 agaagtaata ttatcctatt ccagattcag ttcactatac aattgagttt tcaagcaacc
     8581 tgtttacata atgtgtacat aattaggttc gtgattccac ccttttcacc tttaaaaacc
     8641 tcgctttcgc aaggctcttc tatttataag ataaggcacg tttaaaggtt ttccaaatcc
     8701 ctaaatcatc cgtttgaaga acgagactag catacatgcg tccgataaat cctgttgcta
     8761 ccaccgcaaa aatcactgta atagcaagtg aaatccatgc ttccgctccc tccgcatagc
     8821 cattaatcgt tcgaaacggc ataaagaagg tcgaaataaa gggaatataa gaaccaatct
     8881 tcaagaggag attgtcacca gctgcaccta gagctgtcac tccaaaaaaa ccacccataa
     8941 tcaaaatcat caaaggcgac aaggctttcc ctgagtcttc aggacgagaa accatagatc
     9001 ctaggaaggc tgccaagact acgtacatga aaagactgat caaaataaag agcaaggtat
     9061 tcagtgagat agcatctccc aagtgatcca aaataccaga ctgagccaag aatggcaaat
     9121 ctttaaagag caaaacggca gccagaccac ctacaacata gatcccaata tgcgttaaaa
     9181 tcactagaaa cagagccatc atccgcgcat agaaatagtg acttgccctt atgctagaaa
     9241 agacgacttc cataattttg gtgccttttt cactggcaac ttcctgagct gttacacccg
     9301 cataggtaat cagaatcata taaagaaaga atcctaaggc acctgctgca attgtttgaa
     9361 taaacttttt attttccttg gcttcatcaa tcttttctgt gaattgaatt gtctgcgcta
     9421 agcgtttttc ctgctcttga gacaaggaag cagttgaacg attaagctga ttttgcagtt
     9481 cattgagtgt acctgtaacc tcaaatttaa ttccattttc aagcgatgtt tcgccatgat
     9541 aaactgcctt tagaacacta tcttcttgat caatggtcaa ataacctttt aatttttctt
     9601 ctttaattgc ttctttggca cttgcttcgt ctttatagtc gaagttaaca ccatttacat
     9661 tcttcagtcc ttctgctaca gatggcactg ttgtcactac tgccacttta ttatttttag
     9721 ccatagaaga accttggaga tgcccaattc ctacagagat tcctaaaaag aggaacggcg
     9781 aaatcaccat aaagaagaaa ctccatgact cgacatgccg aagataggtt tccttgatta
     9841 caacccacat atttctcata cttccactcc tgattctagt ttaaagattt catcgatagt
     9901 tggcgcttgt tggtcaaatg ttgcgatata ttgaccttga gtcaagattg ggaagagttc
     9961 ccttccagcg ctctcatcct ccaaaatcaa tttccaactg ccttgtttgg tcaagctcac
    10021 ctgtttgaca tgaggaagat tttccaattc ttccttgctt cgttcacttg aaacaaagag
    10081 acgcgttttc ccgtattgat tgcggacatc ctgaactggt ccgtgcaaga ccacacggcc
    10141 atctcggatc atcagaatat cgtcacaaag ttcctcaaca ttggtcatga catggtcaga
    10201 aaagataatg gttgctccgc gctctttttc ctgaaaaatg acttgtttga gcaattctgt
    10261 attaactggg tccaatccac taaaaggctc atccaagata atcaggtctg gttcatgaat
    10321 cagagtaata atgagctgaa tcttctgctg atttcctttt gacagactct tgattttatc
    10381 tgtcagcttt cctttcactt ccaacctctt catccattga gggagttttt ctttgacttc
    10441 tttggcatcc atgcctttta gagtcgccaa gtagcgaact tgttcaagaa ctgtcaattt
    10501 aggcatgaga ctgcgttctt caggcagata accaatccga gcataggtct cctgacgaat
    10561 atcctgacca tccagaccga tttctccctg atattctagg aatttcaaaa tactatggaa
    10621 aatcgttgtt tttccagcac cattttttcc gactagtccc aaaatacgac ctggtcgcgc
    10681 ttgaaagtca ataccaaaca aaacttgctt ggatccaaaa cttttctcta gacttcttac
    10741 ttctagcatc tttcacctcc gaaatttctt tcactcatta tactcctttt tgatagcctt
    10801 tacaacgttt tgtgtccatt tttagaagac tattgctgtg taaaatatgg cctggagcac
    10861 ttttatactc aatgaaaagc aaagagcaaa ctagaaaact agccgcaggc tgctcaaagt
    10921 acagctttga ggttgcagat aaaactgacg aagtcagctc aaaacactgt tttgaggttg
    10981 tggatagaac tgacgaagtc agtaactata tctacggcaa ggcgaagctg acgtggtttg
    11041 aagagatttt cgaagagtat tagtgataaa tccattatac agtagcaaac ttaatttata
    11101 ccttccgctc ctcaactgtc tatttttaat cctgaattgt tatttgagta actccttttt
    11161 cctcgtaaag ttttcttcct ctaaaacttc tggaaaaagg ctaatagttt cagacaacac
    11221 ttttataaga aacaagttca tctgtcattt caagaaggag taatccttta tctactaatg
    11281 gacggaacag aattcaaccg cttgtccgat atgttttcta aggattatat agtaaaatga
    11341 aataagaaca ggacaaattg atcaggacag tcaaattgat ttctaacaat gttttagaag
    11401 tagatgcata ctattctagt ttcaatctgc tatatctatt atgcacaccc ctataggatc
    11461 taatgaaaat cacaacaggc tcattcatag atagttacct caggaaacta agaaaacgac
    11521 tacaaaggaa gtcgcattca tcgaaaagcg gattaacaac tatcctaaaa aatgcttgaa
    11581 ctacaagtcc cccagagaag acttctggat gactaacttg aacttgaaat ttagcaataa
    11641 ttaattcacc atctaactat atttagtaat tatttcagaa ctgattaata ttaaaattaa
    11701 ctaacgattc aaaggattca tactagccat aaattacgtc catcagagag agactcttac
    11761 tacttttaga ttttagtctt tccagcttca gaatacatct aaactttagg gaaaatgact
    11821 attcgaaagc gcgaatgcct caaaattatc tcagataagc tattcgaaac ttagaatgat
    11881 tttaaattta tggaattgcg attattcgaa acctagaatg catataacct ttagttgaca
    11941 gacctattct aagtctcgaa gggctattta ctttctattc cttatcaaaa aagactcatt
    12001 ccccctttct cctccaaaat atggtatagt agaaatatac tatctatgag gagtttacat
    12061 gtcacaggat aaacaaatga aagctgtttc tccccttctg cagcgagtta tcaatatctc
    12121 atcgattgtc ggtggggttg ggagtttgat tttctgtatt tgggcttatc aggctgggat
    12181 tttacaatcc aaggaaaccc tctctgcctt tatccagcag gcaggcatct ggggtccacc
    12241 tctctttatc tttttacaga ttttacagac tgtcgtccct atcattccag gggccttgac
    12301 ctcggtggct ggggtcttta tctacgggca catcatcggg actatctaca actatatcgg
    12361 catcgtgatt ggctgtgcca ttatctttta tctagtgcgc ctatacggag ctgcctttgt
    12421 ccagtctgtc gtcagcaagc gcacctacga caagtacatc ggctggctag ataagggcaa
    12481 tcgttttgac cgcttcttta tttttatgat gatttggccc attagcccag ctgactttct
    12541 ctgtatgctg gctgccctga ccaagatgag tttcaagcgc tacatgacca tcatcattct
    12601 gaccaaaccc tttaccctcg tggtttatac ctacggtttg acctatatta ttgacttttt
    12661 ctggcaaatg ctttgacacg taaaaaatcc gtttggtttc ccaagtggat ttttaaagcg
    12721 tagattaact atagcttgat actaaatata ctttggtatg gaaatcatgc atatttttcg
    12781 atagtgaggc gaggacttac ctagcctttc cgccgtgata gaaacacctg aaatctaatg
    12841 gtttcaggta ttcggaaact ttgagcctag tgtctcaaag tttaggtatg gaatttcgaa
    12901 gaaagtcgct accgtccgta atcacttaag gaaaggctca aaaatattgt tttcaaccac
    12961 aaaatccgtt tggtttccca agcggatttt gtgctttatt ttgaaacttc ttttgcaaga
    13021 acaaagttcc caagtgtggc agaaccattt cctgcgactg ctggcgtcac gatatagtca
    13081 cgcacatctg gtactggtag gtaaccatta agaagagatg taaatttctc acggacacgg
    13141 tccagcatat gttgttgagc catgacccct ccaccaaaga caatcacgtc tgggcggaaa
    13201 gtcactgtcg cattaaccgc agcttgagcg atatagtagg cttgaacatc ccaaacaggg
    13261 ttgttgagtt caatagtttc cccacgtaca cctgtacgag cttccaaact tggaccagct
    13321 gcataacctt ctagacatcc cttatggaaa ggacaaacac ccttaaactc tttttcaata
    13381 tccattgggt gtctagcaac ataataatga cccatttcag ggtgacccac accaccgata
    13441 aactcaccac gttggatgac gcccgcaccg atacctgtac cgattgtgta gtaaaccaag
    13501 ttttcgatac gaccaccagc attgttacgg gcaaccactt caccgtaagc agagctgttt
    13561 acgtctgttg tgaagtacat tggcacgttt agggcgcgac gaagggcacc aagcaagtcc
    13621 acatttgccc agtttggttt tggagtcgtc gtgataaagc cataagtttt tgagtttttg
    13681 tcaatatcaa tcggcccaaa tgaaccaact gcaagaccag caaggttatc gaattttgag
    13741 aagaactcaa tggttttatc gattgtttcg attggagttg ttgttggaaa ttgtgttttt
    13801 tctacaacgt taaagttttc atcaccgaca gcacagacaa actttgtacc gcccgcttcc
    13861 aagcttccat ataattttgt catgataaac ctcttgtttt tattttcttt attatagcat
    13921 acttcgaaag tctaaatgtc tctatttttt agattttcct ctgtaaatct tactatctaa
    13981 taaaaacgaa caaacatgtc atttgttcgt tttcacatta gagaggattg attagatttt
    14041 cacttcgatc acagcatccc ccttagcaac tgaacctgtt gcgactggag ctactgaagc
    14101 gtagtcacct gtatttgtaa cgataaccat tgttgtatca tcaagtccag ctgcagcgat
    14161 tttgtttgag tcaaatgttc caagaacatc gccagctttc accttattac cttgagcaac
    14221 ttttgcttca aaaccgtcac cgttcataga tacagtgtca ataccaacgt gaatcaaaac
    14281 ttcagcacca tttcttgttt tcaaaccaaa agcgtgccct gttggaaagg caattgaaac
    14341 ttcagcatca gctggtgcat agaccacgcc ttggcttggt ttcacagcga taccttgtcc
    14401 catagctcca cttgagaaga ctgggtcatt gacatcagca agagcgacaa catcaccaac
    14461 gataggagtt acaagtgttt cattttgaag agctgctggc gcaacttctt ctttttcttc
    14521 agccacttca gcttgttttg cagctgcagt tgcgtctact tcatcttcgt aaccaaacat
    14581 gtaagtaaga gcaaaaccaa gggcaaatga tacagctacc ataagaaggt attgtggaag
    14641 ttgtccgtta ccaacataaa gcattgtacc agggatgatg gtgataccat taccagtacc
    14701 agcaagtcca aggatagaag ccaatccacc accgattgca ccagcaatca atgaaaggaa
    14761 gaatggttta cggaagcgca agttcacccc gaagatagca ggctctgtaa tacctaggaa
    14821 ggcagaaaga gcagccggga aagcaagtgt tttcagtttt ggattttttg ttttaacacc
    14881 aaccgcaaca gtagcagcac cttgagctgt catagcagct gtgatgatag cgttgaatgg
    14941 gttagcatgg tcagcagcaa gtaattgcac ttcaagcaag ttgaagatgt ggtgcacacc
    15001 tgacacgacg atcaattggt gaaccccacc aatcaagaaa ccaccaagac caaatggcat
    15061 gctaagaatc gcttttgtag caataaggat gtagttttca acaacgtgga aaactggtcc
    15121 aatgacaaag agtccaagga tagacatgac caaaagtgtc acgaatggtg ttaccaaaag
    15181 gtcaatgaca tctggaacaa ccttgcggac agctttttca aatttagctc cgacaacccc
    15241 gatgatgaag gctggaagaa cggaaccttg caaaccaaca acagggatga aaccaaagaa
    15301 gttcatcgct gttacttcac caccttgagc aactgcccaa gcgtttggaa gtgagccaga
    15361 gacaagcatc ataccaagaa cgataccaac ggcaggattt ccaccaaata cacggaaggt
    15421 tgaccacaca accaaacctg gcaagatgat gaaggctgta tctgtcaaga tttgtgtgta
    15481 agttgcaaag tcacctggaa gtggcatttc aagagcgttg aaaagaccac gcacacccat
    15541 gaagagacct gtcgctacga taactgggat gattggaacg aaaacatcac cgaaagtacg
    15601 gatagcacgt tggaaccagt tcccttgttt agcaacttct gctttcatgt catccttaga
    15661 tgatgttggt aagccaagta caacaacttc atcgtacatt ttgttaactg tacctgtacc
    15721 aaagataatt tggtattgcc ctgagttaaa gaaagcacct tgaacttttt ccaagttctc
    15781 aatcacttct ttattgattt tctcttcatc tttgaccatg acacgtagac gagtcgcaca
    15841 gtgggcaaca ctattgacat tttcacgtcc gcccaaggca tcgatgactt tttttgcaat
    15901 ttcctgattg ttcatttgca aaaatctcct tatataacat tttgttcttg tttgaaagcg
    15961 attttattcg cccttacgac tattatttta tcatgtttta aaaatatgtc aagcgttttg
    16021 cagaaaaaat attctatcca cttagtgggc aagttttaga ttgattgttt ttgactgttt
    16081 catcaggaat tccttgaaaa ataagtttga aaccttggtt aaaaagtctt ttatttcatt
    16141 atctttcaca ttttcgtaaa aatttgattg atttcctgta tttattttat gataatcgtt
    16201 tgacagtttt tcctcttttt taacataaaa ggcttgcatt ttttatcgaa aacagttact
    16261 attaaaagtg ataagatttt tggaggaatg aatggaatgg acaactgagc gtcgttacag
    16321 actttatcaa gattggacgc aagaagaaat tcaacatata aaggaaaata tggcacaatc
    16381 tccatggcat actcattacc atgttgagcc aaaaacagga cttctcaacg acccaaatgg
    16441 cttttcttac tttgatggca agtggatcct cttttaccag aattttcctt ttggtgcagc
    16501 ccacggtttg aaatcttggg cacagctaga aagtgatgat ttggttcact ttaaagaaac
    16561 tggaatcaaa gttttaccag atactccatt agatagccac ggtgcctact ctggttctgc
    16621 catgcaattt ggcgataact tattcctatt ttatacagga aatgttcgcg atgaaaactg
    16681 gatccgtcac ccataccaga tcggtgcttt gatggacaag gagggtaaga ttacaaagat
    16741 tgacaagatc ttgattgacc agccagcaga ctctactgac cacttccgcg atccacaaat
    16801 ttttaacttt aaaggtcaat actatgctgt cgtcggtgga caggacttgg agaaaaaagg
    16861 cttcgtccgt ctctacaagg ctgtcaataa cgactacaca aactggcaag cagttggcga
    16921 ccttgacttt gctaacgacc gtactgccta catgatggaa tgtcctaatc tggtctttgt
    16981 agaggaacat cctgtccttc tctactgtcc acaaggattg gataagaaag ttctagacta
    17041 cgataatatc tttccaaata tgtataagat tggggcttcc tttgacccta aaaatgccaa
    17101 aatggtagat gtgtctcaac ttcaaaacat ggattacggt ttcgaagcct atgcaactca
    17161 agccttcaac gctcctgatg ggcgtgctct agcagttagc tggcttggtt tgccagatgt
    17221 ttcttaccca tctgaccgtt ttgaccacca aggaaccttc tctttggtca aggaactcac
    17281 tatcaaagac gacaagctct accagtatcc agtcgctgct attaaggacc ttcgtgcttc
    17341 tgaagaagcc ttctcaaacc gttcccaaac caagaacact tacgaacttg aactcaactt
    17401 ggaagctaat agccagagcg agattgtctt acttgctgat aaagaaggta agggactttc
    17461 aatcaacttt gaccttgtaa acggtcaagt gacagtggat cgtagccagg ctggagaaca
    17521 gtatgcccaa gaatttggga caactcgttc ttgccctatc gagaatcagg ctactactgc
    17581 tacaatcttc atcgataact ctgtctttga aattttcatc aataaaggag aaaaagtatt
    17641 ttctggtcgt gtcttcccac atgcggacca aaatagtatc ctgatcaaat ctggaaaccc
    17701 aactggaact tactatgaat tagattatgg tcgcaaaact aactgatgtc gccaaacttg
    17761 caggcgtcag tcctactacc gtttctcggg ttatcaataa aaaaggatat ctatctgaga
    17821 aaaccatcca aaaagtcaat gaagccatga gagaattagg ctataaaccc aacaacctgg
    17881 ctcgtagtct gcaaggaaaa tcagctaagt taatcggctt gattttcccc aatatttcca
    17941 atgttttcta tgcagaattg attgataaat tggaacacca actcttcaaa aatggttaca
    18001 agaccatcat ctgcaacagt gaacatgatt ctgagaagga acgcgaatac atcgaaatgt
    18061 tggaagccaa tcaggtagac ggcatcattt ctggtagtca caacctagga atcgaagact
    18121 acaatcgtgt gacagcgccg attatttcct ttgaccgaaa cctatcgcca gacatccctg
    18181 ttgtctcctc tgacaactat gctggtgggg ttcttgctgc ccaaaccttg gtcaagacag
    18241 gtgcccagtc tatcatcatg attacaggga atgacaattc caattcgcca accggactgc
    18301 gccacgctgg ttttgcatcc gtactcccaa aagctcctat tatcaatgtt tccagtgact
    18361 tttctcccgt cagaaaagaa atggaaatca agaatatctt gacccgggaa aaaccagatg
    18421 ccatttttgc ttcggatgat ttgacagcta ttctggtcat taaaatcgct caagaattgg
    18481 gcatttctgt cccaaaagag ctcaaggtca tcggctatga tgggacctac tttatcgaaa
    18541 attactaccc tcaattggct actatcaagc aacctttgga agagattgct tgtctcacta
    18601 ttgatcttct cttgcaaaag attgaaggca aggaagtcgc cacaactggt tacttcttac
    18661 cagttacgct attaccagga aaaagtattt aaacacaaga aaactcagac cgattcgtct
    18721 gagtttttat gatcttaaat tttcgagata gcgctgggct gtctctaggt taaaggtttt
    18781 atctgagatg aggcgctcta ctaggggagc aacttcagat tcactagccc cagctaggag
    18841 agctagggat ttggcctgta gtttcatgtg gccttgctgg atgcccgtac ttaccaaggc
    18901 tttgagggct gcaaaatttt gagcaagacc gatggacacg ataatctggg ctaattctct
    18961 ggcagaagga tttcctagta gatcatgact gagagctaca cgtgggttga ggccgataga
    19021 gccaccctta gtcgctacag gcatgggcag ggtcatctca ccgaccaatt cttctctttc
    19081 aaggtccagc gtccagcagc taagaccttg atagcgtcca tctcgactgg caaaggcatg
    19141 ggccccagct tcgatggcac gccagtcatt accagtggca atcaaaatcg catcaatacc
    19201 attaaaaatt cctttattat gagtagcagc tcggtaagga tcagcctgcg caaactgact
    19261 agccaacgca attttctccg caatctctcg tccttgatcc ttttggcggc tcaagtagcg
    19321 aaaggcgatg cgacagcttg cagtcaccag agaatcagtc gcgtagttgg acaggattcc
    19381 catgagactc tgtccctgac tgagttcttc taagactggt ttcaaggctt ccagcatggt
    19441 gttgagcata ttggcaccca tggcttcctg ggtatcgaca tgaatataaa caacgagaaa
    19501 gtctggttcg ccttttatct gctcgacatg cagatcacgc gccccacctc cacgtttaac
    19561 gatagaagga taggcttgat tggcaagctc caagagctcc gctttcttgc tggcaatctt
    19621 ctcttgcgct agtttaggat tagcaacttg ataaagggct acctgcccaa tcatctgtcg
    19681 ctgatggact tgtgcagtaa aaccacctgc acgcttgatg attttgctgg catagctggc
    19741 cgccgcaacc acagagggtt cttctgtcac atagggaacg gtgtattcct gaccgttgac
    19801 aagtacctcc ggaaccagtg aataaggcag agaaaaagtt cccactacat tctcactcag
    19861 ctggtctgcc acagtcacgc tcatctgttc atccttctcc agactagctt gtctctcagg
    19921 actaaggagc gcctgagctt ttaacagctc gaggcgctct tggtatgatt ttttagaaaa
    19981 tccattccaa cttatcttca ttatttttca accttgctat aacggcgttg gtggtcgaga
    20041 atttcaacca aggcaaaatc ttgattttca tagccagcaa actgggcaga gtttgtttca
    20101 tccaagttta cttcctcaaa aaagaccttt tcatagtctg caacggatag ggcagttcgt
    20161 tggttgagct tgttcaaacg gtctttatcc aaataagctt catatccttc aaccaattca
    20221 ccactgaaga actcagccac agctccactt ccgtaactat aaagggcgat tttatcccca
    20281 gctttcaagc tatctgtatt ttccaagaga gacaaaagtc caaggaaaag tgaacctgtg
    20341 tagatattcc ccaccttttg actgtagaga atagactggt caaaatgctt ttgcaagagg
    20401 tcttttttct cttgaggcaa gttcttatcc atgatttttt tcaagccttt tagcgctaat
    20461 ttaggataag gcaagtggaa acaaacagcc gcaaaatcat ccaaagtaag ctggtagcgt
    20521 ttttgatatt caagccaagt cgttttcaaa ctatccaagt attgttgggt agaatagaca
    20581 ccatttacat aaggagttgt cgagtaattt ggtcgccaga aatccatgat gtcacgggtc
    20641 tgagctacat tgtcattatt aaaggccatc atgcgtggat tttgtgtaat caacatagct
    20701 acacttccag caccttgagt tggttctcct ggagtttcaa taccgtattt ggcaatatca
    20761 ctggcaataa ccaagacctt ggactccgga gaattttcca catgcaattt ggcataatgg
    20821 agggcagcag tcgctccgta gcaggcttct ttaatctcga aactacgagc aaagggctgg
    20881 atgcccagca agccatgcac aaagacggcc gcagccttac tctggtcaat tcctgactcg
    20941 gtagccacaa tgaccatgtc aacttcttgt ctttcttgct cagttaaaat agagtcacta
    21001 gcactggccg ccaaggtcac gatgtcctca gttaggggcg caatactcaa ttccttgagt
    21061 aagagtcctt tacttaattt ttcagggtca attcccctcg cttctgctaa gtcttgtaat
    21121 ttcaagacat attgactggt cgcaaaacca atcttatcaa taccgattgt catatttacc
    21181 tctgttttat cattcatgta aaaaatcgtt ctatactatt ttatcacaaa tggcagtaaa
    21241 agagagaaaa aagacttgat tcaccaaatc aagcctctta ttggtcatca ttttaaagaa
    21301 tgattagttg ctagagagtt caccgatata agtagcttta taagctccat tcacagttat
    21361 cagctcctgg aggatcaaat ttcctgagta aatccttccc atctcatcta caaatttttg
    21421 ataaaactga ctggtcggaa tttctctgac atccttatca aatgtcttgt caagtgtttt
    21481 actaaccttc tcagcaatca attgatgctc ttgccatcca ctttgaaact ctgagcccga
    21541 actagaaacc atgactggga taaacaacaa ggtcagtaga tttacagaca ataaggaaag
    21601 tagtagactt cctgcaaaac tagaatccta gttcatgatt gataatacca gcaatcaaat
    21661 tcattcgtaa tccgaagcgt ttacgatgat ttcgatagat tgttgaaaac attttaaacg
    21721 tttttacttt ggcaaagatg ttctcaacct tgcttctctc cttggatagc gcatggttac
    21781 aggctttatc ttcagctgtt agcggcttga gtttgctgga tttacgtgaa gtttgtgctt
    21841 gaggatatat cttcatgagc ccttgataac cactgtcagc caagatttta ccagcttgtc
    21901 cgatatttct catttctaaa aaccatctac ttccgttgac ttggaactcc gattgctatt
    21961 ttccttgaat gattttaacc acatctccta cgttttggag ttggtcaatt tcttcatcgc
    22021 tgatttcgat actaaattca tcttccagag tcaagataaa ctccatcaag tcaacagaat
    22081 ccgcatccaa atcgtctttc agactcaagg attctgtcac gacaaagtcc tctccctgtc
    22141 gctcttggat aatggtcaca atacggtcaa aaatttcttt ttctgtcatc tcttttattc
    22201 tcctgaaaat tcacgcgcag tctgggcaac cacgtctgtt tctagcatgg tacggatctg
    22261 acgaatcgta ctataaacag ccttggcatc gcttgagcca tgagtcttga caacaggtgc
    22321 cttaacacca aacaagaccg ctccaccaac atctgaataa ttgagctgtt ttttcaaacc
    22381 tctgaggctg tccttgagaa ggagggcacc tagtttcgct cgaagaccac cacctgtaat
    22441 agctgtcttg agcaagccca tgattcccat agctgtccct tcgatggatt tgagcacagc
    22501 gtttcccgtg aaaccatctg ccacaacaac atctgcaacg ccattcatca aatcacgcgc
    22561 ttccacgttt ccgataaagt tcaaactttc atcagccgcc agtaattcat aagtttcctt
    22621 acgaagcggg tcacccttac tactttctgt tccgttgtta agcaagccaa cgcgtggttg
    22681 cgcaatgcca cgaacattct tggcatagaa agaacctagg acagcgtatt gatggaggtg
    22741 ctgggctgta ttttctgcat tagcaccgag gtcaagcatg tcaaaacctt tcccatctac
    22801 agtcggcaat gttgacataa gtccaggacg gtcgatattc ttgatacgac ccacgatgaa
    22861 gaatccagca gccaacaaag cacctgtatt cccagccgaa aggacagcgt ctgcttcacc
    22921 atctttgaca gccttggctg ccaataccat actggcattt ttcttattcc gaatagctct
    22981 cgtaggttca tcatccgaat caatcttctc atccgtatgg ataatgctga cgcgctctgt
    23041 cgctgtcaga tattgcttga ttttagcttc atctccgtag agttgaacct cgatatctga
    23101 aaagtcagat agggcttgat tgacnctgtt agcggcttga gtttgctgga tttacgtgga
    23161 gtttgtgctt gaggatatat cttcatgagc ccttgataac cactgtcagc caagatttta
    23221 ccagcttgtc cgatatttct gcgactcatt ttgaacaact tcatatcatg acaatagttc
    23281 acagcgatat ccaaagaaac aattctccct tgacttgtga caatcgcttg agccttcata
    23341 gcgtggcatt ttttttacca gaatcattcg ctaattcttt ttttagggcg attgatttgt
    23401 acttccgtcg catcaatcat taccgtgtcc tcagaactga gaggagttct tgaaatcgta
    23461 aaaccacttt gaacaagagt tacttcaacc cattggctcc gacggagtaa gttgctttcg
    23521 tggataccaa aatcagccgc aatttgttca taagtgcggt attctcgcac atatagaaag
    23581 cgttgttaat ttatttatct catttttcag aaaattcttt tatttctgta aagtctacga
    23641 tactcgatgt gtttttatat aatgatacag tctgagaatc actgttccgc tagccattcc
    23701 aatagagatt accaaagcca acatgacaac caaggtcgca cttgccagtg ctttattata
    23761 gtcccctgtc acaaaaaagg cagttgttcg gtaggagaga taacctggaa ccagcggtgc
    23821 caaaatggcc aagataaaga ccacagcagg tgtcttataa agaatactta aaatctggct
    23881 gacacaagaa ccaataatgg ctgcaatgaa ggtagctaca atgacattgg tcggttcctt
    23941 gagcaagaga tagattagcc agacagtcat gcccaaaatc cctccaggta agagcataga
    24001 ccgttgcaca ttgagtacga ttaaaaaagt aataatggca agaaaacttg ctactgcttg
    24061 taataaaaag gttgttagtg tcatattagt tcatcaatac caaggcgaca gaagttcctg
    24121 cccctaaagc gagggtaatg agcagggatt caaacatctt actcatacca gagtttatgt
    24181 ggttggtcat aatatcacgg accgcattgg tcaaggcaat acctggtaca aacggcatga
    24241 ccgcaccagc tataatcaaa tctgccgttg aaggaaaacc tgtgtagcga gcccaaaact
    24301 gggcaattat cccaaagaca aaggctccag caaaggctgt cacaaaggga attcggataa
    24361 atttttccac atagagggaa aaggcaaaac caaataaggt cgccactcct gccccaagtg
    24421 cgtcgtagat atttccgcta aacataactg aaaagaaagg agcactaaag gtcgcagcca
    24481 gagttacctg caacttagta tagggaaggg gttgagcttg caaggccgtc aattgcttaa
    24541 aggctgtttc taagtcaatc tgccccccaa ctagctgacg agaaatctgg ttcacatcgc
    24601 agactttttc gatgttataa gaagaggagg tcacgcgctt catgcgcgaa atattggtat
    24661 tttcaataga gaaaaagata gcggcaggca tggcaaggac attgcaatcc acaatcccct
    24721 gcgaatgcgc gattcgaatc atggtatctt ctacacgatg gatttctgag ccacttttaa
    24781 ggagaatagt ccccgctagc ataatcacat caatgacggc atttaattct tttgattctt
    24841 ccatgctttc ctccttttat caactccctc tattctatca caaatctgga ctcaaaaaaa
    24901 atctttgcca tgaaatcatg acaaagattg attactcatt ttgattatcc atctgctttt
    24961 aaggagtagc tgaagttgtt ttaggtttgt agattgaaat cttgactcta gtcttattta
    25021 ggtctacctt ttcacctgct ctaggacttt gttcaacaac catgccttct acactacctg
    25081 caggcgctgt cgtcacttct acaacttcta tattagcttc cttaatccca acaatttgaa
    25141 tcaaattgtt cttagtaaac tccaagctgg aaccaatgta actcggcatg gcaacacttg
    25201 taactttttt agctactgtc aagacaattt gagtaggttt actcacatca taagtcgttc
    25261 cggcacctgg actttgtttc ataatcgttc ctggttcgct ttcgctggac tcttcttcct
    25321 ctatcttaat caaattctca ggaaccttct tctgcttgag ttctgagatt acttctgtag
    25381 agttccgtcc aatatagttc cctaattgaa tcgtcgtagc ttttttagct actgtcaaaa
    25441 caatttgagt tgccttgctc aagtcatagg tcgtaccttc tggtagactt tgcttcagga
    25501 ccgttccagc ctcactctca ttcgactctt cttcctcaat tttaatcaaa ttatctggaa
    25561 cttttttctc ttttaattcc gcgataacat cagaagattt ccggccgaca taattactaa
    25621 tttggaagga ttgtttgcct gatgagacaa ccaaattgat tttcgttcct tcttttcgac
    25681 cagttccagc gccaggatct gtacggataa tccgcccttc ttccaccttt tcactagcct
    25741 ctgtcttctc ctcaccaatc tcaaaattgg cttttttgag cgttgccttg gcctctgcaa
    25801 ctgtctgacc tgccacatct ggaatggcaa tggttgcagg agttctggat agtatccaaa
    25861 taagagaagc tgccaccaat acaaggctgg ccaacaaaat caggtaacgc atcttaaatc
    25921 tatgtttttt cggtgcttgt ggttggtaag tttcctctgt cacagcctgg cttgggtttt
    25981 tgattgattt gtgttctgtc tgcgcttgaa ccttaggaat agatgtcaag gtactctgag
    26041 aaaccttcgg caaggtcttg gtatctgcct tgctcgtttc atcaaagatt aacttacttt
    26101 catttctacg attgtaggac aagctactag acaagtccac atacatctct gaaaccgagc
    26161 ggtagcgatt ggtcaacttt ttagcagttg ccttgataat aacattttct aaagcctgag
    26221 gtacagatgg attttctgca ataacggacg gcaggggttt ctggaaatgc tggagggcaa
    26281 tggtcaccgc gctatccccg tcataaggga tatggcctgt caacatctca tagaaaataa
    26341 tccccatagc atagatatca ctctgcacag tcgctttcga accacgcgcc tgctctggtg
    26401 acaagtaatg aactgagccc aacatcgagt tagtctgggt cagacttgtc tctgcaaagg
    26461 ctacagcaat cccaaagtct gtgaccttgg ccgtcccatc tggtgtcaaa aggatatttt
    26521 gaggtttcaa gtccctgtga acaattcctc gagtatgggc caagcgcata gccaagagaa
    26581 tttgtcccat gatacggact gcttcttcat tagaaagagg ataatgttcc ttgatatagc
    26641 gtttgaggtc tagtccagca acatactcca ttgcaagata ctgttgaccg tcttcctcac
    26701 caatatctgt tatccgaacg atatgaggat ggtctagatc tgccatagct ctcgcttcac
    26761 gctgaaaacg agctacagct atcgggtccg tctggtagtt ggtcctcaga accttcactg
    26821 ccacttcttc cccatctaag attaagtctt ttgctaggta gacatccgcc atgcctcctc
    26881 gaccaatctg tttgacaatc cgatagcgtc cggcaaaaat cttgccgatt tggatcattc
    26941 ttcatcctcc tcgttcatag aaacaagggc aaccgtaatg ttgtctaaac ctcctgcatt
    27001 gttagcaaaa cgaacaagtg tctccgtttt atctgctaaa ggaatatcac tggttacaat
    27061 atcacgaatc tcactgcctg aaatcatgtt ggtcaagccg tcactattga gcaagagata
    27121 gtcacctgac tcaaggataa ctgtcccaaa atcaggctga atttcatctt tttgcccaat
    27181 agactgggtg ataatatttt tttgcggatg agcttctgcc tcttctggtg tcaattgacc
    27241 agccttgagc aattcattaa ccaaggaatg atcgctcgtc aactgatggt attcttctcc
    27301 acgaatcaag ccgatacgcg aatcaccaat atgagcatag atagcctgat tatcaataat
    27361 agcaaggact tccaaagtag ttcccatgcc tctgtaagct tcatcctgac caagctggtg
    27421 aatcttttga ttttcaattt ctaggtaatg ggcgaaccat tcacgcactt cattgactgt
    27481 atcgatctgg gtatcaaccc aagctacacc caggtctgtg accgccattt cactagcgat
    27541 attccctgca cgatgacctc ccatcccatc agctaaaata atcatggtac gtccagctct
    27601 attgacatag tggttgacat agtcttggtt atttgttcgt ttctgaccaa catctgttaa
    27661 taatgaaatt tccatgtgtc agttccttcc taatccgata tcttgcgaaa ttgactgatg
    27721 aagaatccat cacttccata caattcaggt gtaatgagga tacagccgtc tttcatgata
    27781 tccttacatt catgttctag ttttacctgc tcgaactcgg gatgactctc taaaaaggcc
    27841 ttaacgactt gaaaattctc ctctgagacg atagtgcagg tgctataagt tattatacca
    27901 cctttgccta gtatttgaca aacactacct aatatttcta actgaatttc ctgcaaggac
    27961 gcgaaatctg ccgtttcttt attgtatttg atatctggtt ttcggcgcaa aagaccgatt
    28021 cctgaacaag gagcatccac caaaatctta tcaaaggaat cctggtcaaa aaactcatgc
    28081 acctttctgg catccaattt ttgagtttga acccgatctt caactcccag acgttgggca
    28141 ttttcttgaa ttaaatccaa cttgtggtcg tacaagtcca gagcagtaac ctgacctgtc
    28201 gtaagataag aggctatatg ggctgttttc ccacctggag ccgcacaggc atcaagcact
    28261 cgctcatcac cttgtaaatc aagcgtcgga gcaaccaact gactggactc gtcttggatg
    28321 gtaatggctc catccgcaaa caaattatgc cctgcaaaat gcccctgctc cttaaccaga
    28381 ccagtggttg ctaaaaggga attattcgcc tccaacaagg cttggatttc ctcttttcga
    28441 cttaggtctg ttacacgaat actggctttg tttcgcacta acaggctttc aaagatggct
    28501 tttgctctct cctctccgta ttcttccttg agtttggcaa ctagccaaac tgggagagaa
    28561 taggcaatgg agtcacgctt gttttttcgc ttgatgctag caatatctgg ccagccttca
    28621 cgcaagatac ggcgaaggac agcgttgacc aatttttcac tgcctttttt acggagtttg
    28681 gccaattcca ctgcttcatt gaccacagca tgatctggaa tcttgtccaa atagcggagt
    28741 tggtaggcac tcatgagaag aaggacatag agccagctgt ctaactggtc tctgtcttcg
    28801 ataaagtggg ataggtacca ttccagagtc agtttacggg ctaccgttcc atagaccagc
    28861 tcggtcacta agcccttgtc tgctgccaaa agttgacttc cctttagatg cttatttaag
    28921 gcgatatttg agtatgcttg gttcacaaaa acatcctcta gcactgctag agctaaactt
    28981 ctagccgttt ctactttagt caccaaatcg ttctcctaca gtcaatgtac gtccaactcc
    29041 gttgaggaag gaagcaatgt ccatcttagg cttaccagct ggctgcactt gtttgaggga
    29101 tagagcccct tcagccgttg cgacaatcaa ttctttcttg ccgatagaga gaatctcacc
    29161 tggatttccc tgaccttcta ctggtagggc ttcataaatc ttaaagcggt cgcccttaag
    29221 gaaagtatgg gcaacaggcc aggggttcat tccacgaatt tggttaaaga gttgacgatt
    29281 ggttttgttc cagtccagtt tttcttcctc tggctttata tttggagaga aggtaacctg
    29341 actcgtatcc tgcggttcag gtttgatatc accagcaata taggcaggca gagtgtccaa
    29401 aagcaaatca cgaccaacta gcgccaattt ttcaaacaag gtgccaacat tgtcctcatc
    29461 tgtgatcgga atgctgcgac gagaaatcat atctcctgca tccatttcct taaccatttc
    29521 catgatggtc acaccagctt cctcatcccc ttgaatcaag gcataatgga taggcgcacc
    29581 accacggtgt ctaggaagga gggaggcatg aacgttgaca gcaaagtcca tgctatcaag
    29641 gagtttgctt gggagaaact gcccaaaagc agcagtcaca attccatctg ctcctagctt
    29701 cataagatct tccatctctg gacttccaga taatttttca ggttggtaga tagatagtcc
    29761 tgcttccttg gcagcctgct tgactggggt ttcttggata acttttttac gaccaacagc
    29821 acggtctggc tgggtcacaa cggctagaat ttcgtaacgg tcatctgtca aaagtccttt
    29881 taagactgtt gctgaaaagt cgggggtccc cataaagatt agttttgtca tatcttctcc
    29941 ttcttataaa aattgctgcg gctcatggtc aatactgaga cggagctcac tattttcccg
    30001 ttcttgagtc aaggccagga cctggttgag ggtcggcccc agctcatctt ctaaacggta
    30061 tttaattaaa atctggtaat gatagaggtt gtgggtacgg gcaatcggtt ttggcgttgg
    30121 ccccagaatg ggactggtct ctgacaagcc tgaccgcaaa atgttcatga cttcataggc
    30181 acgtttgaaa acctcttctt ctttcttgtg agaaagggta ataccaatcg tgaaatagta
    30241 aggtggatag ccgagttgtc gtctgattcc catttcatag gcataaaagc cttcgtaatc
    30301 ttgatccttg gcaaatcgaa tagcatagtg ctgcgaattg taggactgta tcaagacttg
    30361 acctgctttt tcagcccgac ctgctcgacc tgccacctga gtcaagagct ggaaggttct
    30421 ctcagaagaa cggaaatcag gcagattcaa ggccgtatcc gcatttagaa ctccgactag
    30481 ggtaacattg ggaaaatcca aaccctttgc aatcatctga gtaccaagta aaatatccgc
    30541 ttcccctcgc ccaaactggt caagcaaggc ttggtgactg cctttctttc gagtcgtatc
    30601 cacatccatc ctcagaatgc gagcttgggg aaagagttct gctagctcat cataagcctt
    30661 ctgagttccc gtcccatagt aacgaatact gtggctctta cagttaggac agacctgagg
    30721 aatatccttc gagaaaccac aataatggca gttcatagtc ttggtatcca tatgcaaggt
    30781 cagagaaata tcgcagttgg gacaagtatc caccgtccca cactcccgac acatgacaaa
    30841 gctagaataa ccacgacgat tgagcatgag aaccacctgc tcttttttaa ccagacggtc
    30901 ttggatagcc tctagcaaag gaggcgtaaa gtttgacgtc tcattttgtc cgatatagtc
    30961 tcgaaagtca atcacttgaa cctcagggat tgtagccaaa ggattggcac gttgggttag
    31021 acgtaagtgt tgatagacgc ctttgccagc acgtgcccgg ctctctaagc tcggcgttgc
    31081 agatccaagt accagagttg cttgattata ctgagcccgt aaaatagcta cctctctggc
    31141 atggtaacgg ggattgctgt cctgcttata agccgcttca tgctcttcat caataatcat
    31201 gacacccaga tttttcagag gagcaaagat agcagatctg gcaccaacaa caacttgggc
    31261 atcaccacgc tccaccttgc gccattcatc atacttttca ccattggata atcctgagtg
    31321 aagaatggct accttgtccc caaagcgtgc tataaaacgc tcggtcattt gaggagtcaa
    31381 ggaaatctca ggtaccagca aaatagctgt cttgccctta tccagggcac cttggataat
    31441 ctgcaagtaa acctcggtct tcccacttcc tgtaatccct tgaagtagaa agggaggttg
    31501 agaactgcca atagaactca caaccgcatc acgcgcctgt ctttgttctg gatttaactc
    31561 caaaggtcta cttgcttcaa ttccttcaaa ataagcagcc gagcgttgaa cttccttttg
    31621 gactatggta acagcacctt gatccacaaa gaagttgact tgctctcgcg agtaggactc
    31681 taacaagcta gccaaggaag cgctctctgg atgagacagc agataatctc tcagttccaa
    31741 ctttttcttg gcacgtgtag aaatctcaac accttctaat tgggcatggt caacctcata
    31801 ccaagactgg gtcttgacct tcttttgatc gactgcctga tattccagac caagcaggcc
    31861 ttttctagtc aaacgcatca tttcagcttg cttggcaagg tctagtgaag aaaaggctag
    31921 cgaatcttct gaaccaaaca ggcgcactcg ttcttcctga ctcaagcctt ccagaggata
    31981 gagaatcttg tcatagctag aattcagaaa tcctggaagc atggccttga ggatagagat
    32041 tttgtaggag aagacagatt tgcgtaactc ctcagccagc cagagttgtt ctggcgtgag
    32101 aacaggagaa aaatccagca cctctgcaat atcttttaaa tcttgctcca tctcttctcc
    32161 atctgattgg gacttcaaac caagaacaat cccttgaatc aggcgattac ccttaccaaa
    32221 aggcacatga acccgcatcc caacttccag cattccctca aattcctccg gaatcctgta
    32281 actatagggc tggtccgtct gcatcaaggg cacatctacg ataatcttag ctagggccat
    32341 cttctcacct cctccttgtc agtacattct tgcaatagaa aaaataagat tgagtccccc
    32401 caaccttaaa ttttttcacc atcttctttt tctttagcaa tttgctcttt gattttcttt
    32461 tcttcttctt ctttgcggcg tttttcttct tcgatacggc gacgcactgc ttcacgtttt
    32521 ccttctggat ctgggtgaat tgtaacgttt cctgattcga tttcttctaa agcgcgaaga
    32581 gttgattttt cagacttgaa accttgagtt gctggggcac ctgcttccaa ttcgtgggca
    32641 cgttttgctt ccaagattac gagtgaatat tttgaaggaa ccttgtcgag caaggtatca
    32701 atagagggtt ttaacatcat ttgcttgtac ctattttcta aattttatcg ggtagttgga
    32761 gattttggta acatctcctg atagtgacca atgacacgat ccacacagaa gtgttctgct
    32821 tcaatcacac atttgacacg ttcagcagct aggggtacct gatcgttgac aatcgcataa
    32881 tcatactcac gcatgagggc aatttcttcc ttggcctttt cgattcgttg ggcaatcact
    32941 tctgcactat ctgttccacg acctaccaag cgatcttgca attcatccaa atctggtggt
    33001 gtcaggaaga taaagacagc atctggaacc tttttcttga cctgaagagc accctgaact
    33061 tcaatttcaa ggaaaacatc gattcccttg tccaaggttt cattgacata ggtcagagga
    33121 gttccatagt agttaccgac atattctgcg tattccaaca tctgtccttg acgaatcagc
    33181 tcttcaaatt cttcacgagt acggaagaaa tagtcaacac cgtccacttc tccaggacgt
    33241 tgtgcgcgtg tcgtcatcga tacagaatat tgaaattggt tttcagaact ctcaaaaatc
    33301 tctcttctaa ccgttccttt tccaacccct gaaggaccag aaaaaacgat tagtaagcct
    33361 cggtctgcca ttgtgtctcc ttttagtcaa tctgtgaaat aacatttctc tagaataatg
    33421 gcaaaaagcc agattatcct ttacagtctt tctatctagt gtaacaaaaa agcagtaatt
    33481 tttcaactgc tctttcttat ttatttagca taatctactg cacgaagctc gcgaatcacg
    33541 gttaccttga tatttcctgg ataatcgaga ttgttttcaa ttttcttacg aactttgtga
    33601 gccaagattg tgactttgtc gtccttgatt tttcctggat tgaccatgat acgaatttca
    33661 cgtcctgctt gaagggcaaa gctagtttgc actccttcaa agccgttagc aatttcttcc
    33721 aaatcatgga gacgcttgat gtagctttca agagactcac tacgagcacc tggacgggct
    33781 gcgctcaagg catctgctgc agcgacgata actgctatca cgctctcagc ttcaacatct
    33841 ccgtggtgac tagcaatcgt attcaccaca actgggggtt ccttgtactt acgggccaat
    33901 tccataccga tttcaacgtg gctaccttca acctcatggt caatggcttt cccgatatcg
    33961 tgaaggaatc cagcacgacg ggcaagagcc gcattttcac caagttcgct cgccatgata
    34021 ccagccaact tagcaacctc aatcgaatgg cgcaaaacat tttgtccata tgaagtacgg
    34081 aactgcaaac gtcccataat cttcatcaag tctggatgaa ggtttggcgc accaatttca
    34141 taggcagcag cctcaccgta ttcacgaatc ttattgtcaa tctcttgacg gtttttctca
    34201 accaactctt cgatacgagc tggatgtata cgaccatctt tgagcaacat ttccatagtc
    34261 atacgggcaa tctcacgacg aatcggatca aatcctgaca aggtcaccac ttctggtgta
    34321 tcgtcgataa tcacatcgac ccctgtcaaa ctttcaaagg tacgaatgtt acgaccttca
    34381 cgaccaataa tgcgtccctt catagtatcg tctggcagat gaactgttga gtttgttgac
    34441 tccgctacat attcaccagc gatacgttgc atagcttgaa ccaagatgtc cttggccatt
    34501 ttgtcagaac gttccttgac ctcttgctca gcttcgcgaa tgcgactggc aatctccctg
    34561 gtcaagtttt cctctgtctg aaccaagata atatctcgtg cttctgcctg agacagagca
    34621 ccaatacgct ctagttctgc ttctttttgt ctttcgactt cctctaattg ctcttcacgc
    34681 gcatcaaggt ttttcgctct atcagaaata ctttgttctt tttgttcaag tgtttgttct
    34741 ttactcgtca aattgtcgtc cttacggtca aggctagtag ctctctctgt caaacgactt
    34801 tcgatttgtt tgagttcttg acgttctgat ttgaattcag cgtccacttc ttcacggtat
    34861 tttctggctt cttctttggc ctccaatagt gcttcttttt taagagactt gctttcacgt
    34921 ttggcttcat taacaagtaa atccgcttca cgctcagctt gtccacgtaa attagttgct
    34981 tcttgttcag catttaaaag catcaactct gcagcttcct gagatgattt catcttagct
    35041 gagatgctga catatccaat gactaaacca atgatgacgg caaaaacagc aatcgcaagc
    35101 gacatgattt ccatgttttt acctcatttt attgttattc cgaatgacat acattctttt
    35161 acattctacc ataaaaaagt gattttcaca aacctaaaat agaatatgtt ttggggaatt
    35221 tggaacacat ttaccaaaat aaacttgttt tttagaaata gtagtttagt agagacttga
    35281 gaaaaagcct acctttcaat agacttagta atgatcttta aaggacaaga aagccacgct
    35341 atctccatcc atcatataaa tcaatcgatt ttctgcatca atacgacgtg accaagctcc
    35401 ttggtagtca tacttgagtg gttctggttt acctattcct gtaaagggct cacgttgaat
    35461 atccttgatt agtttattga ttctttttaa cgttttctta tcctgatttt gccagtagca
    35521 ataatctgcc caggcatctt ctgtaaactt gagcagcatt tcttactcct caataacatg
    35581 gacctgagta cttccagcac gaacttgagc cattcctcgc aaaaccttat cagaaagttc
    35641 cttattttga gcaattctca gggtttcttg gatactatcc cactcactct ttgaaaggac
    35701 tacaatgtcc tcgtctggat ttttattgac caccgttaaa ggctcaaatt catcatttac
    35761 ctttttcatg tagtctttta aatgatttcg gaatgttgag taaaggactg cttccataac
    35821 catacctcgt tttagctctt ttccactatt atacacaaaa agaaagaaat tgtcaggaac
    35881 ttgtacaaga ttttcttttc tatctattta tactcaatga aaatcaaaga tcaaactagg
    35941 aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgcgat ttgaatttga
    36001 ttttcgaaga gtattattcg taaaaaatct caaaaagcct accttttagt agacttagtt
    36061 tgtttctatt ctaatcggca ctcttccaaa attttgctct gctatacttg gatttcctag
    36121 ttggtaaatc tggtctgctt tttgggtcat agcatcccaa ggttctttgc caattcggct
    36181 gactagactg acctgacctt tcaaagactt gagatgttgc ctaccttttt cagtaaatcc
    36241 aaggacatga atggcttctg gcaagtcact ttctctagcc tgcatcaaaa tataggtcaa
    36301 taggcgtctg acacgcgcct tggtgtaacg tttggtagtc actaactcga ccaattcttc
    36361 cacagactgg gctgttttaa tagcttcttt aatgcgcaca gccatttctt gattgacctg
    36421 atagatggtg gttaggtcgg gatttgacaa gatttgatag cggagcaagg gaaaatagtc
    36481 ttcccagatc accttactga cctgctcaaa tagggcaaca gaaggcataa aacgttctaa
    36541 gaaatcttgg tccttctgat gttgacggag ggctgtcgcc gaggcaaagt ccacatcttt
    36601 attcacagaa tggtaacctg ccccctgacg ctgaatcgga tgcagcttga tatttcgtcc
    36661 tgcaaccgcc ttggcatagg ccagagcaag aacatgattg ggggtattac ctgaaaaatc
    36721 aagaccagca aattccttcc acatagcttg ggttttctgg ggataggaaa gggaatcagg
    36781 cagattttcc acaaatttct ccatctcagt acctttctct gtgtataagt cagcgatttt
    36841 ctgataatct cgaacttcct ctgttccaaa aactagacta tcaatgccca agcgatccaa
    36901 gatatccaca gctccttgac caaagaaatc agctgcctga acactgacta aaaagggcaa
    36961 ttccactacc aagtctgcgc cattttccag cgccatctgg gcccttgtcc acttatccac
    37021 aatagcaggc tctccacgct gcatgaaatt ccctgacatg gcaacaattt tcagtccctc
    37081 tgcctgatcc agcaggtatt tatggccatt atgaaaagga ttgaactccg cgataatacc
    37141 tgtgatggtc atgctaatct cctacttctg cgccacaaaa aaccaacggg tgctagtttc
    37201 tgttggctcc ttatcctcaa agtctgcata gagtttgaag gacttgaatc cagcctgttc
    37261 cagtaagatc tcataggtca agatctcata ggtcctctcc tcatgtactt catcgtggcg
    37321 actaaaggaa ccgtcagcct ccttgataaa gaaagtcagc tcatgcacga tggagtgagg
    37381 aacttcgtcc tcatatgtat cccaaagcat agcaaaatct tccgcatttt catggtagga
    37441 atagccaggg aatacttcat ctgtctggta ggtcgagtgc acgtcaaaga tgaaaactcc
    37501 ctcttcattc agcgcattgt acacgtcctt aaagacgtcc cctacttcca cctcatcctg
    37561 catatagcag atagagtccg aataacacgt gacaaaatcg tatttccctg ccttggacaa
    37621 attcagcata ttaccttcta taaaagcaat cttttgcttg gctgaagttg ctctcttctc
    37681 cgcaatcttc aacatatccg cactcaagtc aagtccagtc acatcaaaac cagcctgaga
    37741 gaagcgcact gattgaattc ctgtcccaca agccaattcc aagagtttct ttctctcctt
    37801 ggtcttaggc aaatgacgca gagaaaaatt cgtccatttg tcgtataaac tatcgtccat
    37861 gaccgcatca tagaccgccg caaaggtttc ataagtcgcc ataaaacatg ataccaagtc
    37921 cgcccgtaat tcgatagaaa attaggagcc ttacgatgga gccgagctcc aaggaaggct
    37981 atctattttc cgagaattac aggacgggtt caaatccttt ctaagataca aagagcctta
    38041 aaagcaaaga gtacatagga aactttcttc cctatcgtca gatacaaaga aagttacttt
    38101 ttatctcagc ttttagctcg tgttcagttt cgaaatgaaa caaacacgag gccctttacc
    38161 tttctatcaa tttttctaaa ataagcaaag aaacccagtt gactacaact gagttcatct
    38221 tctaagcaag agcttctgaa atatctactg aattcgcctc atgccatagc ttctctagat
    38281 tataatgggc acgcatttct tctgaaaaga tatgcacgac aacagcaccg aggtccagta
    38341 agacccaacc tccagctgca tcgccttcga catggctacc tttaaagcct gcttgagcta
    38401 ctttttcacg gatattagct gcgatagcgt ccaactgacg actattcatt gagctagtga
    38461 tgacaaagta gtccgtcaca ctagtcaaat cttgtacatc aagtgcgagg atatcctccg
    38521 cacgtttctc atcagccgct ttcacgacta gttctagtaa ttctttttcg ttcatttaat
    38581 cctcttttta gaaaatatgt ttgtaatcta ggacatctgc aaagcgctcc tcccaaatgt
    38641 cctcataaaa ttcattaatc gtttctgctg gaatgtcatc cccatcaaag gttgtgacag
    38701 caccttctgg aacaataagc tgatagccat attcaaaggc aaccttgaca gaggtatcca
    38761 cacaatattc tgtctgcata ccacataaaa ctaatttttc aatcccctgc ttatccaagt
    38821 attcttttaa gccagtttct ttgaaaatac tgttatactt cttctgaaag accttttcag
    38881 caggttttcg atttaaaagc gcagataact gccaatcttc tgatgtttga gcttcagagt
    38941 tctcaatatg ttgaacatag ataatttcaa tattcttgct tctagcctgg ttttgtaaat
    39001 aagaaatttt ttccaataga ctttttgtct ggaacccagt ttctactaaa acattctgaa
    39061 catcaatgat tataaaagcc gtcttcattt agtcctcttt caaatagtgc acaaaggcgt
    39121 tataggtttc aagggtttgg ggatagatgg ggaatccctg atgagctaga tactccacgg
    39181 tacgagctgt ttcgtaggcc accgccttat tgagcgatag acttgcaatc tcacgcgcca
    39241 catccactcc aggaaatgcc cgattgtgct cgatatagtc tgcgacgtag atgaccttat
    39301 ctaggtctgt catttgacca gctccgactg tatgaatttc aatggctcgc agaatttcag
    39361 aatcatgcaa atccaaatct tcctgaattt tgtaaattcc gaccatacca tgccagacat
    39421 tattgcccca gtttttgagg tcagggtcta gctggtaacg gtcaatcaag gctagaaatt
    39481 cctgatctga caacttttta gcatagtcat gaagaagacc tgctagactt gctttctcaa
    39541 catctacacc aaagcgctga gctaattcca tagcggcacg ctccacacct agacaatggg
    39601 ttagacgttt ctcaggtaga agctctgcca ttttttccaa caaggcctca cgggagcagt
    39661 tgatatagtc ttgataggac atcagtagag cccctccttc tcgatgtagt ctagcactgg
    39721 ctgaggtagg agaaagttgg gtttccgacc ttgggcaagg aagtcccgca ccatgctgga
    39781 cgagatatcc atgagcggta cgtccaccca gataactgga taggaagtcc ctaccttgta
    39841 gcgtggacgc tgaaccccca caaactgaac catgtcaacc agttcatcaa ttcggtacca
    39901 cttaggcaga tagtcaacca tgtcggcacc gatgataaag taataatccg tatctggatt
    39961 cttctctgtc aaaatcttca tggtgtcgta ggtgtaggaa atacccttgc gctccaactc
    40021 aatggtttca atgactaggc cgtcaattcc ctcaattgcc aactcaagca tcttgagacg
    40081 atggtgttca gggatggttt cctttttatc aacgtgagga ggttggtatt caggcatgag
    40141 aagaacttga tccagtccca actgttgccg tacttgatcc gcaacaatga gatgggcatt
    40201 gtgaacaggg ttaaaattcc cccctaaaat cccaacttgt ttgcgttttt tctccttgat
    40261 ttctggctcc aactctacct tggtaaaggg agtcaatagt tcgattgtca taggctagtc
    40321 ccctttattt ctctataaaa acagttattt ggagtttcgg tcttagattt ctttgacttt
    40381 cttagaaatc ttgcgatttt ctttcttact agattgttta aacaaaatca agatgcgtcc
    40441 tattttttgg actgtatcca caccgatttc ttcttccaaa atttcagcta cttcgtggat
    40501 gttttcatct gtgttttgta agagagtaac cttgattaat tcacgcgcat caagagcttg
    40561 acggacgctg gttttgattt ggtcgttgag tccatttttc ccgatttgga tgataggttt
    40621 gagggtgtgt gcctggctgt tgaggaaggc acgttgtttt gatgttaatg acataatttt
    40681 cttccttgtt tttggatagt tattttaggt ggtgagggac ggtcggaact aattttccaa
    40741 agatttcatc tttgaaaaat ggatttcctg acctcacaat tgagccttgg tctcaattgt
    40801 gccccttgcc aatctacaga ttggcaatca caccacggca ataactatcg ctatatgagc
    40861 tcactttgtt cgctcagcga ttttgtttta aataattgct tttcgtgtga cgacggcgac
    40921 gccctctggt gcccagacgg cgacttttgc tgtgcctgtt acacgaatcc agcctaggcc
    40981 tgagatgact aggtctgtct tatctttaat ggtaaagaca tgctggacta gccttgggaa
    41041 atcttctttt tccttgctat ttggtggtgt cagaagagtt cccaggtgct tatcgtagaa
    41101 agcactagct ccttcaagct tgctacgatg gagtttgagt tcattatcaa agaaagcagt
    41161 aaatccttgc ttt
//
