LOCUS       NZ_JVCZ01000028        23252 bp    DNA     linear   CON 16-JUN-2024
DEFINITION  Streptococcus parasanguinis strain 540.rep1_SPAR, whole genome
            shotgun sequence.
ACCESSION   NZ_JVCZ01000028
VERSION     NZ_JVCZ01000028.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus parasanguinis
  ORGANISM  Streptococcus parasanguinis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277843)
  AUTHORS   Roach,D.J., Burton,J.N., Lee,C., Stackhouse,B., Butler-Wu,S.M.,
            Cookson,B.T., Shendure,J. and Salipante,S.J.
  TITLE     A Year of Infection in the Intensive Care Unit: Prospective Whole
            Genome Sequencing of Bacterial Clinical Isolates Reveals Cryptic
            Transmissions and Novel Microbiota
  JOURNAL   PLoS Genet 11 (7), e1005413 (2015)
   PUBMED   26230489
  REMARK    Erratum:[PLoS Genet. 2017 Apr 14;13(4):e1006724. doi:
            10.1371/journal.pgen.1006724. PMID: 28410416] Publication Status:
            Online-Only
REFERENCE   2  (bases 1 to 277843)
  AUTHORS   Salipante,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2014) Laboratory Medicine, University of
            Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABYSS v. 1.3.5
            Genome Coverage                   :: 13x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001071295.1-RS_2024_06_16
            Annotation Date                   :: 06/16/2024 18:04:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,247
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,147
            CDSs (with protein)               :: 2,147
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 8, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2 (5S, 23S)
            partial rRNAs                     :: 8 (16S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 15 of 37
            Pseudo Genes (incomplete)         :: 21 of 37
            Pseudo Genes (internal stop)      :: 7 of 37
            Pseudo Genes (multiple problems)  :: 5 of 37
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:49:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 244657
            Orig. end                         :: 267909
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JVCZ01000028.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23252
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23252
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23252
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:13252](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13252)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(126..140)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 19.31"
                     /tool="antismash"
     misc_feature    complement(189..198)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(316..606)
                     /locus_tag="ADG88_RS08035"
     CDS             complement(316..606)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080188.1"
                     /locus_tag="ADG88_RS08035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5960 family protein"
                     /protein_id="WP_001080186.1"
                     /transl_table=11
                     /translation="MNRKELYDDKLQLDYFSDSYLRFESDFYKYSALDIPLTFITDDIL
                     RTMAMSQKHYFKLNKSKSLDGRDHYFVFSIKMNKDSSGIRQYEYQRHCFSL"
     gene            complement(596..961)
                     /locus_tag="ADG88_RS08040"
     CDS             complement(596..961)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981955.1"
                     /locus_tag="ADG88_RS08040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_049474971.1"
                     /transl_table=11
                     /translation="MMNRSYLPFLFAREYQDRGMAKWMGFFLSEHSSSLWEEKNKEDVS
                     ITLSMEEKVLLVRQLYTNTFPATFIFKHSNRRKVVSGIVKEIGKEFISIKSDIGFLRLE
                     WLDILGIQIEGEELHES"
     gene            complement(958..2373)
                     /locus_tag="ADG88_RS08045"
     CDS             complement(958..2373)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149971.1"
                     /locus_tag="ADG88_RS08045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_049474972.1"
                     /transl_table=11
                     /translation="MTWFDYSLEPKSDIAFIDMKSFYASVECVDRGLHPLKTSLCVMSR
                     ADNSAGLILASSPMFKKVFGKSNVGRSYDLPFDVKTRKFSYYNAKKQGLPTTIDYVRYI
                     EEWAKSTVIVPPRMDTYIAVNMEIQKIFQDFAAPDDIYPYSIDEGFIDLTSSLNYFVPD
                     KSISRKDKLDIISAAIQKKIWRKTGIYSTVGMSNANPLLAKLALDNEAKKTPTMRANWS
                     YEDIEKKVWAIPKMTDFWGIGNRMEKKLHHLSIFSIKELAQANPDLIKKELGIMGLELW
                     FHANGIDESNVHKPYKPKSKGIGNSQVLPRDYIKQRDIEIILREMAEQVAVRLRRAGKK
                     ATVVSIHLGYSKVEQKRSIHTQMKIEPTNQTALLTNYVLKLFHTKYTSGAIRNVAVNYS
                     GLVDESFGLISLFDDIEKIEKEERLQSAIDAIRTEFGFTSLLKGNALDQASRTIARSKL
                     IGGHSAGGLDGLK"
     misc_feature    2329..2339
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.4"
                     /tool="antismash"
     gene            complement(2376..3059)
                     /locus_tag="ADG88_RS08050"
     CDS             complement(2376..3059)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492697.1"
                     /locus_tag="ADG88_RS08050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_049474973.1"
                     /transl_table=11
                     /translation="MFSPTKLKRKRESQVLSQSQLASSLGISRASYFNWESGKTKPNQN
                     NLSKLSEILNVDLRYFESEYEIVETYLKLTERNQEATLNYATELLNKQNAKVVDIPERF
                     AYKVYEKLSAGTGTAYFDDGNYDTVYFNHQFDYDFASWVFGDSMEPTYENGSVALIKQT
                     GFDYDGSIYAIDWDGQTYIKKVYREENGLRLVSLNRNYSDNFAPYDENPRIIGKIVGNF
                     MPLED"
     misc_feature    complement(3053..3066)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.02"
                     /tool="antismash"
     gene            complement(3275..3547)
                     /locus_tag="ADG88_RS08055"
     CDS             complement(3275..3547)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /locus_tag="ADG88_RS08055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_049474974.1"
                     /transl_table=11
                     /translation="MFTTFFKKKQDNSDVFKKLIHRLSDMSAQDLEKIDRLLDIIFTPD
                     QGSEQLKTEATYREETLDDTLKEAKNQLHKEQLEKNLERFRKNNQ"
     misc_feature    complement(3523..3536)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 24.02"
                     /tool="antismash"
     gene            complement(3585..3968)
                     /locus_tag="ADG88_RS08060"
     CDS             complement(3585..3968)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /locus_tag="ADG88_RS08060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5945 family protein"
                     /protein_id="WP_000159212.1"
                     /transl_table=11
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNDVNYEAAFQK
                     RKQAPVTESNPSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEELHT
                     LIDTKNKDNKKLQSIYDAISELH"
     gene            complement(3965..4198)
                     /locus_tag="ADG88_RS08065"
     CDS             complement(3965..4198)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /locus_tag="ADG88_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5965 family protein"
                     /protein_id="WP_000152419.1"
                     /transl_table=11
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQS
                     ISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            complement(4249..5334)
                     /locus_tag="ADG88_RS08070"
     CDS             complement(4249..5334)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /locus_tag="ADG88_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="toprim domain-containing protein"
                     /protein_id="WP_049474975.1"
                     /transl_table=11
                     /translation="MNIEECKQISILDVANRLGISFKQVSSRVYEHPEHDSFRIFSTTN
                     TFKWFSRDIQGDVIDFVRLVKGISFKEALAFLSEEPLKKEAVQENRLRPFYYPLKRVED
                     SNCSLARYYLTECRGIAEEIVQKMIQQGLIAQASWKTNETVEPVIVFKSFDHRHKLQAA
                     SLQGIYKNNSLPRERLKTILKGSHGHVGISFDIGKPNRLVFCESFIDLMSYYELHQQSL
                     SDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTLIPSKLLPLINTIRDTTSYFDNH
                     PDLLTLAVDCDDAGKDFSDKLSQSGFPVFLDFPDNESGKEKVDWNDVLREKKSDLQLMI
                     ETAKETLGNQPVRQTSQCLEL"
     gene            complement(5344..5985)
                     /locus_tag="ADG88_RS08075"
     CDS             complement(5344..5985)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /locus_tag="ADG88_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_000933082.1"
                     /transl_table=11
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIELA
                     AAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSSQN
                     DAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTETRT
                     VKLSYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSIPSLPNTTTK"
     misc_feature    6035..6050
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     gene            6145..6342
                     /locus_tag="ADG88_RS08080"
     CDS             6145..6342
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /locus_tag="ADG88_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004249782.1"
                     /transl_table=11
                     /translation="MNKLKEENLRRALSHIERHKQAINTSNNSEDNDFHKLLLQFSYEV
                     YERIKANKKPYPNLDSDKVF"
     gene            complement(6480..7370)
                     /locus_tag="ADG88_RS08085"
     CDS             complement(6480..7370)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ADG88_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_049474976.1"
                     /transl_table=11
                     /translation="MDLSFLDWISLIANIVTILGISGFLNDYLNKRKDEKKISNDVLSN
                     AIKLASLSLDIYDLKEQKIYRASDYIKVIKTNLEEWKDLINNFEINRDWQQEEKYNLPD
                     TEEHNLTSTEQYNDGEEYMSTDYVFCDGESQQCLYEEEIQDYINNFKKLSKNEQENILK
                     IAIYNDIFDQHWKNFEGDLRLSESIIRDFVDAILLSITSEGLTYNAYLNSDFETLRVIQ
                     IEIDELLKYIELYVNSNVKYAIALKNPFIIFQEKWKSNHNLPIEFSMEDYAIRRLSIIE
                     KLLLLLDKIDSELPK"
     gene            complement(7580..>7807)
                     /locus_tag="ADG88_RS11415"
                     /pseudo=""
     CDS             complement(7580..>7807)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /locus_tag="ADG88_RS11415"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="iron-containing alcohol dehydrogenase"
                     /pseudo=""
                     /sec_met_domain="Fe-ADH (E-value: 7.6e-12, bitscore: 38.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEGKSDEECADYAIAEIEKISETVGIPKKLTELGIEEKNFDFEYI
                     SKNALIDACAPGNPFMPTLEETIDFYKELF"
     gene            complement(7871..9994)
                     /locus_tag="ADG88_RS08090"
     CDS             complement(7871..9994)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756060.1"
                     /locus_tag="ADG88_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_065426947.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.3e-30, bitscore:
                     98.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVKFIQQLSETSCGLACMAMILDYYGHEANLYELCCDFENSRD
                     GLSIRDIKNIASYFGLDSKASEILNVKTFLGNKIVEPYIALTSNAHYIVVEKHNEHSVV
                     FIDPEQGRITEDISNFANNISGIVIFFSPNRKFTKKKKHNNFFKILKIGKIDIKRLSYI
                     SLISILVQSLTLLLPLLTRFIIDNVISKGEMYRLGMLISVFSLIIFYALFSFIRTKLII
                     IVEKRYIFTLKDKIVGKIFTLPMKFFDSRSSGEIVTRINNLDSLEKIISSGISSLLIDL
                     STIIIAFIAMAMISLYFTLIITCFAIFLFIVLYFLLKKLEEKNSNFISSKELTQGYLME
                     IFSNLLFLKVSAKGDVSYTKWKEMFSNELKFDVERENYLNIFQTFISIYRLVPNLLILI
                     LGGLEVQQHMMSLGNLMSFLSLVSLLLSPITLIVQNCFQFQFCFTILDRVFDIIYTPEE
                     KNQFSISKLPPFEMMTFRNLSFAYSSAYKVIYDISLTIKKGERIAIVGRTGCGKTTLIK
                     LLLRLYDVEKNTILYNGNDINLFDLNSYRKSFGVVLQNDVMFNDTVISNIDLTHSHSME
                     DVISAASLAELDIEINNMPMGYYTSIGDNGNNLSGGQRQRLAIARAILQNPEIMIFDEG
                     TGQLDTITEKKIMDNLKHKGITQIFITHRLSNAQEYDNIIVMDNGKIIDSGKHDELCGK
                     EGMYKRLFETSYN"
     gene            complement(10001..13252)
                     /locus_tag="ADG88_RS08095"
     CDS             complement(10001..13252)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080431.1"
                     /locus_tag="ADG88_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_049474977.1"
                     /sec_met_domain="DUF4135 (E-value: 1.8e-107, bitscore:
                     353.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-64, bitscore:
                     212.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRKLNITDFKDASYFSERKISSHDLGDGLKSRKRKEYWDNFIGE
                     GSNEFWEYLQEKNDFSKHDLDIFLEEHTYDVKDIDSFSHMNEFIEFFFKRNDYTLPEFY
                     IVDSEGKRKPIFSNFVIPFLKFAAYKLEDNLSSQNLKVTRDVLNSLLIALFQQILNISY
                     RTLILELQVLKEQNMLNGETGEKRFKYFSEIYLSDHFWDILKEYPVMFRLIIENIQNWV
                     TNNVEFLTNLKEDKALLQEHFSINGELTKIESGVSDFHNHGKSVYLLWFGTNKLVYKPR
                     DLILDVKFQNLLSWYNLKFNKNLYVTNILNRGNYGWVEYIEHLPCTYESDFIQFYTHLG
                     YLLFLLFAMRGNDIHFENIIAKGNRPVLVDIETLFHNTTEYRKEYETADKLIFSLLEKS
                     VKRVGILPNIVWGKDGNSGVDISGLSSSAGEMIPIERASIMHSMTDEMKIGYEQSALQS
                     KDNQPFILSGKDVDLNSYKNYVSAGFKEAYEIISKDPSSIEEFLVEIEKFNNAYSRQIM
                     RPTQFYSNLIQTSYHPSFLRSGLDREMLFSKVWKIVFEDKKVQRIASSEFESLLLGDIP
                     LFQTKISDRFLCSELTKYQNFFNISGIELAIQQIKDFCQKDMEFQLNLIETTLNYDPSY
                     NLVQDSFVPLKPSVKVIHNLNHKEIQETKSRIVPLTEKIADYLSKISYSGTSGDICWVD
                     MNILGEKTNDWNMVPIGCDLYNGISGIMLFYLFLYLETKKKDYLIYLKKCYRSLKYYLD
                     SRKQFATHSQVLFGGFSGETPIIYVLLLLKTRMPEHFNSDELDVYIYDIIDDLKKGYRY
                     DENFDVLVGSAGAIIHLLNVFEVTRDEELLILAHDLFSHLEKNSTKITVEGQDGRAWKG
                     TMASNPLAGFAHGVSGIVWALSKLSRYFPEDKKIKTLIKQGIIFENSMFDTEKSNWSDY
                     RETESGIKYKDIVENIPVSWCHGAPGILISRLELYKNNTLNVEFRRTMKSDMDVAIDTT
                     IKYGFGKSHCLCHGDLGNLNILFYVAKKMSSEHLYNVVYSYLNTILDDLESENWKCGLP
                     YKNSPSLMSGIAGIGLGLLTLNNLSIPSVINLEIW"
     gene            complement(13335..13550)
                     /locus_tag="ADG88_RS11420"
     CDS             complement(13335..13550)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="ADG88_RS11420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_049522134.1"
                     /transl_table=11
                     /translation="MSDWKKPIYESLSTEGNPAGDILRELSDSEMDQTMAGGTARSYCA
                     CYSGENSCGRGCTITTECPFLTFICC"
     CDS_motif       complement(13437..13550)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSDWKKPIYESLSTEGNPAGDILRELSDSEMDQTMAGG"
                     /locus_tag="ADG88_RS11420_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13335..13436)
                     /prepeptide="core"
                     /locus_tag="ADG88_RS11420_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.50"
                     /molecular_weight="3417.9"
                     /monoisotopic_mass="3415.4"
                     /core_sequence="TARSYCACYSGENSCGRGCTITTECPFLTFICC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDWKKPIYESLSTEGNPAGDILRELSDSEMDQTMAGG"
                     /leader_location="[13436:13550](-)"
                     /alternative_weights="3435.9"
     gene            complement(13696..14424)
                     /locus_tag="ADG88_RS08100"
     CDS             complement(13696..14424)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928810.1"
                     /locus_tag="ADG88_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_049474978.1"
                     /transl_table=11
                     /translation="MLMLELTKLRRRKILYMIPFVAILLFLLEFMIGHQIYQGHSYGSV
                     NGWYVENGFFFLNYYFLLPFASMILVDLIRIEQVSKTISNLRLIPVDLKQLLQAKFMLA
                     LLINLLVSEFTFLAMLVLELMDGDFAFSSLTMLSWGLVYGAIAFAYTLSAGIIVLFLGK
                     YRKELILALPLAFLLSFAGLFALTTVVGRYYLANLLLIILEEFTVLTVSVYAIWLITLV
                     ACLLYLLADKRMMNIIFAYK"
     gene            complement(14425..15165)
                     /locus_tag="ADG88_RS08105"
     CDS             complement(14425..15165)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886369.1"
                     /locus_tag="ADG88_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_049474979.1"
                     /transl_table=11
                     /translation="MLDLVKIEFLKQRHQKLNFVVYGVVSLYLALICYYVNDARGLFDS
                     FPFVYKFSLSYLNFLILPLYCVSYTIQAFGVEYRYRIMNNLKLASANLMKTFWAKILYI
                     EINALCIMLFTYISVSLFALLSRFSSTVSLSLLLRFFYLCMSSGILIPMGVFPLVALVM
                     IKVRGKEIVGNLVGVMYVLVSFFLARTSPNISPVTSANSLIWEGNREGVVLQQPAILSI
                     IVLGLSLLVLSFLSIKSWLRKVDE"
     gene            complement(15158..16093)
                     /locus_tag="ADG88_RS08110"
     CDS             complement(15158..16093)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245733.1"
                     /locus_tag="ADG88_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_049474980.1"
                     /transl_table=11
                     /translation="MRNPVIQTFNLSKSYDGKIVLDRIDFTLRQGEIYGLLGRNGTGKT
                     TFIKAILGLTAMDSGEVNILSEKLLGEFSKDLLSQIGVVLDSASFYPNLTGPENLSIFA
                     RLRGISLKQVEQALQVVGLDGENKKLFKQYSLGMKQRLAIANAIMHQPKILILDEPTNG
                     LDPIGILEMRRYLKELSTNHGISILISSHIISELEKLVDRVGILHDAHLMAEKTMQELI
                     DGADKRKIHLIVSDAPQAKEVLCRINLQEQISILSDIELELQGESPTFDIAVVSNSLKD
                     NGIVLKEYSYKNNESLEDYFKRITGGEGIA"
     gene            complement(16272..16445)
                     /locus_tag="ADG88_RS12065"
     CDS             complement(16272..16445)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000025229.1"
                     /locus_tag="ADG88_RS12065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_049474981.1"
                     /transl_table=11
                     /translation="MSILAKFRKIIFMLSFLGLFGSGFFYKEPVNQSQYIWESRIIQQA
                     ATTKEVDLGLAD"
     gene            16636..17496
                     /locus_tag="ADG88_RS08120"
     CDS             16636..17496
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000025784.1"
                     /locus_tag="ADG88_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_049474982.1"
                     /transl_table=11
                     /translation="MTILSDKLKSKRKEKGFSQKTLSEGICEQSQISKIERGNYMPAAD
                     LLYKLANRLQVPLDYFFDEQIEMTSNITPFKKLAEKLLEDRNYEALEYLLNLEKEKSQY
                     LSTEDEFYLLWIQAIILFYLHSSKDEAIANLENALPKLSVSSSVYLKLLNTLSNFYFSV
                     GRDAEYEENNSLLISLYQEKDLNHQEYLFGYIRVKHNFAYYLHSKGKELEAVQEALETI
                     DFCKQKETSYQLAPLLTIVANAGKDFLKHDEILDYYLQARDICKIYEHKLLMAKIDHFL
                     KDKDR"
     gene            complement(17579..17869)
                     /locus_tag="ADG88_RS08125"
     CDS             complement(17579..17869)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998897.1"
                     /locus_tag="ADG88_RS08125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5966 family protein"
                     /protein_id="WP_000998897.1"
                     /transl_table=11
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASGLFLIGFVSFLIFVEV
                     YGIYLLFTETELYTADLAQNGLFGFTTFFIIFNLVLLALACWAGYKWKRGY"
     gene            complement(17883..18167)
                     /locus_tag="ADG88_RS08130"
     CDS             complement(17883..18167)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /locus_tag="ADG88_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5962 family protein"
                     /protein_id="WP_049474983.1"
                     /transl_table=11
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSIR
                     ELTSQLEIALQNHRGVDFEEYEKEDYLELVQKLEEFDSSLATHYRQLID"
     misc_feature    18736..18749
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 22.35"
                     /tool="antismash"
     misc_feature    complement(18799..18808)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.26"
                     /tool="antismash"
     misc_feature    complement(19105..19118)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 22.31"
                     /tool="antismash"
     misc_feature    complement(20385..20399)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: strong, score: 28.9"
                     /tool="antismash"
     misc_feature    23216..23230
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
ORIGIN
        1 actacgtata tctcttttca tatgactttt cctccttcat tgatacctgt actgacaatg
       61 taagcttaca gacactgtca gtacattttt caaaatatct tcaacgtttt tgtaaggctt
      121 tgcgagctca gatattgtgt ccacaatatt ccaaaaatca tatcgcctgc catttcaaac
      181 ctcactgttc aaaaaacaaa cgatatgaaa atgtggtggc acgcccccaa acccccaaga
      241 taaatctaaa ttaaaaaaag tataacaaat actttttgat aaaattatca cagaaaaaag
      301 agccctatcg gactcttaca aactaaaaca atgtctctga tattcatact gtctaatgcc
      361 actactgtct ttgttcatct tgatagaaaa aacaaaataa tggtcacgac cgtctaaaga
      421 tttgcttttg ttaagtttaa aataatgttt ttgagacata gccattgtgc gtaaaatgtc
      481 atcagtgata aatgttaatg gaatgtctag agcagagtac ttgtaaaaat ctgattcaaa
      541 ccgtaaataa gaatcagaaa aataatctag ctgcaattta tcgtcatata attctttacg
      601 attcatgtaa ttcctcacct tctatctgga taccaagtat atctaaccat tctaatcgaa
      661 gaaatccaat gtctgatttt atagatataa actctttccc aatttcttta acaatacccg
      721 atactacttt tcttctattt gagtgcttaa aaataaacgt tgcagggaat gtattcgtat
      781 aaagttgacg aacaagtaaa accttctctt ccattgataa agtaattgag acatcttctt
      841 tatttttttc ttcccaaaga gaacttgaat gttctgacaa aaagaatccc atccacttag
      901 ccatcccacg atcttgatac tctcttgcaa ataaaaacgg caaataagaa cgattcatca
      961 ttttagccca tctaatcctc cagctgaatg accaccaatg agtttacttc ttgcaattgt
     1021 tctagaagcc tgatccaggg catttccttt caatagtgaa gtaaaaccaa attctgttcg
     1081 aatagcatcg attgcggact ggagcctttc ttctttttct attttttcaa tatcatcaaa
     1141 taatgaaatc aatccaaagg attcatctac taaaccagaa tagttaaccg caacattcct
     1201 aatagctcct gaagtatatt tagtgtgaaa taactttaaa acgtagtttg tcagtagtgc
     1261 tgtttgattg gtcggttcaa tcttcatttg agtatgaata gatcgtttct gttccacttt
     1321 agaatatcct aagtgtatag aaaccacagt cgctttttta ccagctcttc tcaatctaac
     1381 tgcaacttgt tctgccatct cacgaagtat gatctcaata tctctttgtt taatataatc
     1441 tcttggtaaa acttgagagt tccctatccc ttttgacttc ggcttataag gtttatgaac
     1501 attgctttca tcaataccat tagcgtgaaa ccacaactct agtcccataa tcccaagctc
     1561 ttttttaatc aagtcaggat tagcctgtgc caattcttta atcgaaaaga tacttagatg
     1621 atgtaatttc ttctccattc tatttccaat tccccagaaa tctgtcattt taggaatagc
     1681 ccatactttc ttttctatat cctcatagga ccaattagct ctcattgtcg gagtcttttt
     1741 agcttcatta tctagtgcta acttagctaa taagggattg gcattagaca tgcctaccgt
     1801 tgaatagatt cctgtttttc tccaaatctt tttttgaata gcagccgaga taatatctaa
     1861 tttatctttc cgactaatac ttttatctgg cacaaaataa tttaatgaac ttgttaaatc
     1921 aataaatcct tcatcgattg agtagggata aatatcgtct ggtgccgcaa aatcttgaaa
     1981 aattttttga atttccatat tgactgctat ataagtatcc attctcggag gaacaatcac
     2041 ggttgatttt gcccattcct caatataacg aacataatct atcgttgttg gtaaaccttg
     2101 cttcttagcg ttatagtaag agaacttcct agtttttaca tcaaatggta aatcatagga
     2161 acgtccaacg tttgattttc caaagacctt tttaaacata ggagaggaag caaggattaa
     2221 cccggcagaa ttatctgcac gactcataac acaaagcgaa gtcttaagtg gatgtaagcc
     2281 tctatcgaca cactctacac ttgcgtaaaa agatttcata tcaataaatg caatgtcact
     2341 ctttggttcg agactataat caaaccaagt catactcaat cctctaaagg cataaagttt
     2401 ccaacgattt tccctatgat acgaggattc tcatcataag gcgcaaaatt atctgaatag
     2461 ttccgattga gtgaaactaa tcgaagccca ttttcttcac gatacacttt cttaatatag
     2521 gtttgaccat cccaatctat cgcatagata gacccgtcat aatcaaagcc cgtttgctta
     2581 ataagagcta ccgaaccatt ttcatatgtc ggttccattg aatccccaaa cacccacgat
     2641 gcaaaatcat aatcaaattg atgattaaag taaacagtat cgtaattacc atcatcaaaa
     2701 taagctgttc cggtaccagc tgataatttt tcataaactt tataagcaaa acgctcagga
     2761 atgtctacaa ccttggcatt ctgtttgttc aacagttctg tagcataatt aagtgttgct
     2821 tcttgattcc tttccgttag tttgagatag gtttcaacta tttcatactc tgattcaaaa
     2881 tatcgaagat ctacattcaa aatctcactc aatttgctta aattgttttg attaggcttt
     2941 gttttacctg attcccaatt aaagtatgag gctctactaa ttcccaaact ggatgcaagt
     3001 tgagattgag ataatacttg actttctctt tttcttttta atttagtagg tgaaaacatt
     3061 tgttctcctt tttgtaagtt tattaactaa caaaagaata ccatagctgc tggaaaaaat
     3121 caagagttta ataaccccca agatttaaaa taatcataaa ctgtgcttaa tttatactta
     3181 cattgttagg aaaccatcac ttaagaaagt tataactttt gaaaaagata aagaaccaga
     3241 aaaaatagaa aataaaaaaa gaatcgttgg tgcgttattg attgtttttc ctaaatctct
     3301 ctaaattctt ctccaattgt tccttatgaa gttgattctt agcttctttt aatgtgtcgt
     3361 ccaaagtttc ttctctgtaa gttgcttctg tttttagttg ttctgatcct tgatctggag
     3421 tgaaaatgat atctagcagt cggtctattt tttcaagatc ttgggcagac atatcagata
     3481 gtctatgaat tagcttctta aatacatcac tattatcttg ttttttctta aaaaatgttg
     3541 taaacatcta taacctctca aaaaaagcag cctataagga ctgcttagtg taattcagaa
     3601 atcgcatcat aaatggactg caatttctta ttgtctttat tctttgtgtc gatcaacgta
     3661 tgtagctctt caattttctt ttgactgctt tgaatatcgc tattgttatc cgcaatcaat
     3721 cttttaagat gttgctgata acttgtagtg atatctgtct cttttcctgt tctaacctct
     3781 gtaactttag gtttagaact aggatttgat tccgtcacag gtgcttgttt tcgcttttga
     3841 aaagctgctt cataatttac atcattacct ccttgatgat ttccaaataa ggccgcaatt
     3901 ttatctggat cttcttgatt ttctgattta ctttctaatg gttgattaaa attccaatct
     3961 tttgtcattc actcatttca tcctttctaa attcagaatc atcgaattgt ctttctttac
     4021 caaaggcatg gtcaagagct tcttcaaaac tcatgtgact aatgctttga cgccttttga
     4081 acgtcgcaaa catcgctgtc tctagttgct ctttgtaagc agctagtttt tctgtctctc
     4141 ttgctacctt actttcttgc ctagtgacct tttcttctaa gcgttcaata atggtcatat
     4201 acgatcctcc ttcattttaa tattagctaa aacatcttga ttttgttatc acaattctaa
     4261 acattgagag gtttgtctta ctggttgatt ccccaatgtc tcttttgcag tctcgatcat
     4321 caattgtaaa tctgatttct tttctctaag gacatcattc cagtctactt tttctttccc
     4381 tgattcatta tcaggaaaat ccaggaaaac aggaaatcct gattgagata acttatcaga
     4441 aaaatctttt ccagcatcat cacaatctac cgcaagtgtc aataaatcag gatgattatc
     4501 aaaatagctg gtggtatcac gaattgtatt aatcaaaggc aataactttg aaggtattag
     4561 tgtatctaaa aattccaact tctgattttc ttcagctatt agtcgtaaag tttgataagc
     4621 gacaacagac ctttttaatc cctccataga taccaaacga acatcagaaa gactttgttg
     4681 atgaagttcg taatagctca tcaagtcgat gaacgattca caaaagacca gtctatttgg
     4741 tttaccaatg tcaaaggata ttccaacatg tccatggctt ccttttagaa tcgtttttaa
     4801 cctctctctt ggaagagaat tattcttata tatcccttgt aagcttgctg cctgcagctt
     4861 gtgacgatga tcaaagcttt taaaaacgat aacaggttca actgtttcat ttgttttcca
     4921 actagcttgt gctatcaaac cttgttgaat catcttttgt acgatttctt ctgcgattcc
     4981 tctacattct gttaaataat atctggctag actacagtta gaatcttcta ctctctttaa
     5041 aggataataa aatggtctca atctattttc ttgaacagct tcttttttta aaggttcttc
     5101 agaaagaaaa gctagagctt ctttaaagga aattccctta acaagtcgaa caaaatcaat
     5161 aacatcacct tgaatatctc ttgaaaacca tttaaaagta ttggtagttg aaaaaattcg
     5221 gaatgaatcg tgttcaggat gttcatagac acggctagaa acttgtttaa aggaaatacc
     5281 taaacgattg gctacatcaa gaattgaaat ttgcttacat tcctctatat tcataaaaca
     5341 tcatcatttt gtcgtagtat ttggcagtga tggtattgat gatgattctt ctaaagtttt
     5401 aggagttgcc ttatctaaat catctaaccc agatttccaa acctgtactt gattgaccaa
     5461 taacttacct ggtagtttcg aataagacaa cttaactgtt cttgtttctg tctgattagt
     5521 ctttgattgg ttggcattct ttaaatcaga tacataggtt acattataag agaccatggc
     5581 aatggcttga ttcgtagtct gattgacaaa gatatctgct ttttcaaaat gataatccaa
     5641 aatataatcc ttatacactt ggttcatagc atcattttga cttgacaatt cttgagaata
     5701 agccgattca gtcatataag gttgaatacg tgtattattt tctccgagct tttctttcgt
     5761 atagtactgc gtcaaaaatt cttttacagt atccgatgac aaaatgctgg ctttatcttc
     5821 tgcttgtttg tcctctacaa gtttagctgc agccaattcg atttctttgc gactttgttt
     5881 agcagtagaa tgttgaccag cagtatatcc catcatgaga ataaagctag ttgcggctac
     5941 tgctccaaca ctaattaagg ctttagtttt gactttattt aacatcttag accttctttc
     6001 tataaaaact aggtcaagaa taacaaaaag aacttgtaag ttttatcaca tcacaacgaa
     6061 aggtaattcc tacatttcag gcgccaaatc gtacagttca gagaaaaata tcaaaattag
     6121 ctgtcttcag cttataatat aaatatgaac aaattaaaag aagaaaattt gagaagagct
     6181 ctttctcata ttgaacgaca taaacaagcc ataaatacaa gtaataatag tgaggataat
     6241 gattttcata aattattact ccaatttagc tatgaagtat atgaaagaat caaggctaat
     6301 aaaaaacctt atccgaattt agattcagat aaagtctttt gactaacttt ttccttataa
     6361 aaaattttat ataaaaatat ctctaaataa aagttttatc cagagatatt tttacaccta
     6421 aattctaatt tttattatat attttagatt ccattattgt ataaaacttt aacaattttt
     6481 tactttggga gttcactatc aattttatct agtaacagta gtaatttttc aataattgat
     6541 aatctacgaa tagcataatc ctccattgaa aattcaattg gaagattatg atttgatttc
     6601 catttttctt ggaaaataat aaatggattt ttaagagcaa ttgcatattt aacatttgaa
     6661 ttaacataca attctatata ctttagtagc tcatctattt caatttgaat tactcttaat
     6721 gtctcaaaat cactatttaa ataagcatta taagttaaac cttcggatgt aatagataaa
     6781 agaattgcat cgacaaaatc tctaataatg ctttctgata atcttaaatc cccttcgaaa
     6841 tttttccaat gctgatcaaa aatatcatta tatattgcaa tttttaatat gttctcttgc
     6901 tcattttttg aaagtttttt gaaattattt atataatcct gtatctcttc ctcatacaag
     6961 cattgctgac tttctccatc acaaaataca taatctgtac tcatatactc ttccccatca
     7021 ttatactgtt cagttgaagt caaattatgc tcctctgtat ctggtagatt atatttttct
     7081 tcttgttgcc agtctctatt tatctcaaaa ttatttatta aatctttcca ttcttcaaga
     7141 tttgttttta ttaccttgat ataatcagaa gctctataaa ttttttgttc ctttagatca
     7201 taaatatcga gacttaaact tgctaatttt atcgcgttag ataaaacgtc attagaaatt
     7261 tttttctcat cttttctttt attaagataa tcatttaaaa acccacttat ccctaaaata
     7321 gttacaatat ttgctattag actaatccaa tctaaaaatg ataaatccat ttttattcct
     7381 cctaaagtaa ttataaaatt agtataacac aaaaaaaata aatattttca gtttaaaaac
     7441 taccaaatag atttcaataa gaagggaagg ataatctata ttttactcca tactacaaaa
     7501 aaagattgag cattgtacag tacaaaactc aatcctttaa ataacattta agttagcaaa
     7561 caattaaact gattatttct taaaacaact ctttataaaa atcaatcgtt tcttctaaag
     7621 ttggcataaa tgggtttcct ggtgcacatg catcaatcaa ggcattctta gaaatgtatt
     7681 caaagtcgaa atttttttct tcaataccaa gttcagtcaa tttcttagga atacctactg
     7741 tctcagaaat cttctcaatc tcagcaattg cgtaatcggc acactcttca tctgatttac
     7801 cttctacttg atactatgcg tgttctgctt ttcgagactt tttgtacaga ctcataaaac
     7861 ctaatcaaaa ttaattatat gaggtttcaa aaagcctttt atacatacct tctttaccac
     7921 ataactcatc atgttttccg ctatctatga ttttaccgtt atccataaca ataatattat
     7981 cgtattcctg agcgttagat agtctatgag ttataaaaat ttgggtaatt cctttatgtt
     8041 ttaaattatc cattattttc ttctctgtta tagtgtccaa ttgaccagta ccttcatcaa
     8101 aaatcataat ctctggattt tgcaaaatgg ctcgagctat tgctaagcgt tgcctttgcc
     8161 cacctgataa attattacca ttatccccaa tactagtata gtatcccata ggcatattat
     8221 taatctctat atctaattca gctaaacttg ctgcagaaat gacatcctcc atagaatggc
     8281 tatgagttaa atctatattg gaaatcacag tgtcgttaaa cattacatca ttttgtaaaa
     8341 caactccgaa actcttccta taactattta aatcaaacaa attaatatca ttaccattat
     8401 ataaaatcgt atttttctct acatcataca gccgtagcaa taatttaata agtgtagttt
     8461 ttccgcaacc tgtcctcccc actatagcaa tacgttcacc tttcttaata gttaatgata
     8521 tatcataaat aactttatag gcactactat aagcaaaact caaatttctg aaagtcatca
     8581 tttcaaatgg gggtagttta gaaatagaaa attgattttt ttcttctgga gtataaatga
     8641 tatcaaaaac tctatctaaa attgtaaaac aaaattgaaa ttgaaaacaa ttttgtacga
     8701 ttagagtaat aggtgaaaga agcaaagaaa ccaatgataa aaatgacatt aaattcccca
     8761 gagacatcat atgctgctgt acttcgagac ctcccaaaat taaaattagt aagtttggta
     8821 cgagtctata aatagaaata aaagtctgaa aaatatttag ataattttca cgctctacat
     8881 caaatttaag ctcattacta aacatttctt tccacttagt atatgaaaca tctccttttg
     8941 ctgagacttt caaaaataat aaattagaaa aaatttccat cagataacct tgagtcaatt
     9001 ctttagaact gataaaattt gagttctttt cttccagttt ttttaacaaa aaatataaaa
     9061 caataaacaa aaatatagca aaacatgtga ttataagtgt gaaatataat gaaatcattg
     9121 ccatagctat aaaagcgata ataattgtag atagatcaat taacaaactt gatattccac
     9181 ttgaaattat tttctctaaa gaatctaaat tattgattcg agttacaatt tcacctgaag
     9241 atctactatc aaaaaatttc ataggtagag tgaaaatttt gccaacaatt ttatctttta
     9301 atgtaaatat gtatctcttc tcaactataa tgattaattt agttcgtatg aagctaaata
     9361 acgcataaaa tataattaag gaaaaaactg aaataagcat ccctaaacga tacatttctc
     9421 ctttgctaat tacattatca ataataaacc ttgttagcaa aggtaataat aaggtgagac
     9481 tctgtaccaa gattgatatt aaagaaatat aacttagcct tttaatatca attttaccta
     9541 tcttcaatat tttaaaaaaa ttattgtgtt tctttttttt agtaaatttc ctatttggtg
     9601 agaagaagat tacaatacca gatatattat ttgcaaagtt tgatatatct tctgttattc
     9661 taccttgttc tggatcgatg aatactacac tatgctcatt atgtttttcc actacaatat
     9721 aatgagcatt actagttaaa gctatatagg gttctacaat tttgttcccc aaaaatgttt
     9781 taacatttaa aatctcagac gcctttgaat ccaatccaaa ataagaagct atatttttaa
     9841 tatctctaat ggataatcca tcccttgaat tctcaaaatc acagcataat tcatataagt
     9901 ttgcctcatg cccataataa tctaaaatca ttgccatgca tgctaaacca caactggtct
     9961 cagataattg ttgtatgaat tttacctttt tcaatttgaa tcaccaaatt tctagattaa
    10021 ttacagaagg aattgataaa ttattcaaag ttagtaagcc taatcctatt ccagctatcc
    10081 cactcattag acttggagaa ttcttatacg gaagaccgca tttccaattt tctgattcta
    10141 aatcatcaag aatcgtatta agataggagt aaactacatt gtataaatgc tcagaggaca
    10201 ttttcttagc aacataaaat agaatgttta aatttcctaa gtctccatgg catagacagt
    10261 ggctttttcc aaaaccatat tttattgttg tatcaattgc tacatccata tcagatttca
    10321 ttgttcttcg aaactctaca ttcaatgtat tatttttata cagttctaat ctacttataa
    10381 gtatacctgg agcaccatgg caccacgaaa cagggatatt ttcaacaata tccttatatt
    10441 tgataccact ttcggtttct ctataatcag accaattaga tttttcagta tcaaacatag
    10501 aattttcaaa aattatacct tgtttaatta gagttttaat ctttttatct tctgggaaat
    10561 atctactaag ttttgacagt gcccacacaa ttcctgagac tccgtgtgca aaacccgcta
    10621 aaggattgga agccatcgtt cctttccatg ctcttccatc ttgcccttca acagtaattt
    10681 ttgtagaatt tttttctaaa tgactaaata aatcatgcgc taatatcaag agttcttcgt
    10741 ctctagtaac ttcaaataca tttagcaaat gtataatcgc accagcagaa cctacaagaa
    10801 catcaaaatt ttcatcatat ctataccctt tttttaaatc atcaataata tcatagatat
    10861 aaacatctag ttcatcagaa ttaaagtgtt caggcatcct tgtcttcagt aacaacaata
    10921 catatataat aggggtctct ccagaaaaac ctccaaacag tacctgagag tgagtagcaa
    10981 attgctttct tgaatctaaa taatacttga gagatcggta acattttttc aagtatatga
    11041 gataatcttt tttcttggtc tccaaatata agaataaata gaataacata atacctgata
    11101 taccattata cagatcacat ccgattggaa ccatattcca atcattcgtt ttctctccca
    11161 gtatgttcat gtctacccag catatatctc ctgaagtacc actatatgaa attttagata
    11221 aatagtcagc aattttttct gttagaggta caattctact tttagtttct tgtatttctt
    11281 tatgatttaa attatgtatc acttttacag atggttttag aggtacaaaa gaatcctgaa
    11341 ctaaattata agaaggatcg taattcaaag ttgtttcaat caaatttaat tgaaattcca
    11401 tatccttctg acaaaagtct tttatttgtt gaattgctaa ttctattcct gaaatattaa
    11461 agaaattttg atatttcgtt agttcagaac ataagaatct atcagatatt tttgtctgaa
    11521 ataatggaat atcacccaat aataatgatt cgaattctga actagctatt ctttgtactt
    11581 ttttatcctc aaaaactatt ttccaaactt ttgaaaataa catttcccta tctagaccac
    11641 tccttaaaaa actaggatga taagatgttt gtattaaatt agaataaaat tgtgtgggcc
    11701 tcattatttg tctagaatac gcattattaa atttttctat ctcaaccaga aactcttcta
    11761 ttgatgaagg atcttttgaa ataatttcat aagcttcttt aaagccagca gaaacgtaat
    11821 ttttatatga attcaaatca acatccttgc ccgatagaat aaaaggctga ttatctttac
    11881 tttgcaatgc ggattgttca taaccaattt tcatttcatc cgtcatacta tgcatgatac
    11941 ttgcacgttc aatcggaatc atctctcctg cgcttgaact tagaccgcta atatccaccc
    12001 cagagttccc atctttaccc caaactatat taggtaaaat acctactctt ttcacagatt
    12061 tttctaataa agagaatatt agtttatctg ccgtttcgta ttcctttctg tattccgttg
    12121 tattatgaaa taatgtttca atatcgacaa gaactggtct attaccctta gctatgatat
    12181 tttcaaaatg aatatcgttt cccctcatag caaataataa gaataacaag tatcctagat
    12241 gtgtataaaa ctgaataaaa tcagattcat atgtgcatgg taagtgttct atgtactcta
    12301 cccatccata atttccacga ttcaaaatat ttgttacata tagattttta ttgaatttca
    12361 ggttgtacca gctaagcaag ttttgaaact tcacatccaa tattaaatct cttggtttat
    12421 atactaactt atttgttcca aaccaaagga gatatactga ttttccatga ttatgaaaat
    12481 ctgacacacc agattcaatc tttgttaact ccccattgat agaaaaatgt tcctgtaata
    12541 atgctttatc ttcttttagg tttgttaaaa attctacatt attagtaacc caattttgaa
    12601 tattttcaat aattaatcga aacataacag gatattcttt taatatatcc caaaaatggt
    12661 ccgataagta tatttctgaa aaatatttaa atcttttttc tccagtttca ccgtttaaca
    12721 tattttgttc tttcagaact tgtaattcta atatcaatgt tctgtaagaa atattcaaaa
    12781 tttgttggaa taacgcaatt aataaactat tcaagacgtc tctagtgact ttcaaattct
    12841 gactactcaa attatcttca agtttatagg cagcaaattt caaaaatggt atgacaaaat
    12901 tactgaaaat aggttttcgt tttccctcac tgtcaactat ataaaactct ggtaatgtat
    12961 aatcatttct cttaaaaaag aactctataa attcgttcat atgtgaaaat gaatctatat
    13021 ctttcacatc atatgtatgt tcttccaaaa aaatatctaa atcatgttta gaaaaatcat
    13081 ttttttcttg taaatattcc caaaattcat tagaaccttc tccaataaaa ttatcccaat
    13141 actcttttct ttttcttgat ttcaaaccat cccctaaatc atgactagaa atttttcttt
    13201 cagagaaata agaagcatct ttaaaatctg ttatgtttaa ttttcgattc attttcaact
    13261 cctaaatata aaacaacagg tgacatccta cttttaggtg tcacctatcc caaagattca
    13321 atagaattaa tctattaaca acaaatgaat gttaagaaag gacactctgt ggtgatagta
    13381 caaccacgac cacaagaatt ctctcctgaa taacatgcac aataagatct agctgttccg
    13441 ccagccatag tttgatccat ctcgctatcg ctaagttcac gcaagatatc cccagctgga
    13501 ttaccttctg tacttagtga ttcgtaaata ggttttttcc aatcagacat aattgtttaa
    13561 tccctttcta gttactgatt tctcttatta aatatagtga cacctcaaac ctttgggatt
    13621 aaaaaattca aaagagatac cagtaacaaa tatttaaatc cgctgtaatt ataactctga
    13681 aagttatgat tacagtcatt tataagcaaa aataatgttc atcatgcgtt tatctgccaa
    13741 caaataaagg agacatgcca ccaaggtaat cagccatatg gcatatacag aaactgttaa
    13801 aacagtgaat tcctccagga tgattagtag taaatttgcc agataatacc gcccaacaac
    13861 cgttgttaaa gcaaacaaac ctgcaaatga caataaaaag gcaagtggca gggcaaggat
    13921 aagttccttc cgatattttc ctaagaagag gacaataata ccagcagaca gtgtataagc
    13981 aaaagcaatt gctccataaa caagtcccca agataacatt gtaagactag agaaagcaaa
    14041 atcaccatcc attaactcta ggactagcat agccaaaaaa gtgaattcac tgactagtag
    14101 attaatcaac aaagcaagca taaacttcgc ttggagtaat tgtttcaaat cgacaggaat
    14161 cagtctgaga tttgaaatcg ttttagacac ttgttctatt cttatcaaat ccactaaaat
    14221 catgctcgca aaagggagga gaaaatagta gttcaaaaag aagaaaccat tttctacata
    14281 ccagccattc acactaccgt acgaatgccc ttgataaatc tgatgaccaa tcataaactc
    14341 taacaaaaag agcaggatgg ctacaaaggg aatcatatac agtatctttc gtcttcttag
    14401 tttagtcaat tctagcatca acatttattc atccaccttt cttaaccaag atttaatgga
    14461 caagaaagac aaaacaagta aagataaacc tagtacaata atcgataaga tagctggctg
    14521 ttgaagtacc actccttctc tgtttccttc ccagattaaa ctgttagcac ttgttactgg
    14581 actgatattt ggactcgtcc ttgctaaaaa aaatgacact aaaacataca tgacaccgac
    14641 caaattccca actatctcct tgcctctgac ttttatcatg accaaagcaa ctaaaggaaa
    14701 tactcccatg ggaattaaga taccactact catacaaaga tagaagaatc ttaataataa
    14761 agacaaactg actgtcgaag aaaagcggga tagtagtgcg aataaggaaa ccgaaatata
    14821 ggtgaataac atgatacaca gagcgttgat ttctatatac aaaatcttag cccagaatgt
    14881 cttcattaga tttgctgaag cgagtttcaa gttgttcatg atgcgatagc gatattctac
    14941 accaaatgcc tgtattgtat aagaaacaca atacaaaggg agaatcaaaa agtttaaata
    15001 agacaaagaa aatttataga caaagggaaa ggagtcaaac aatcctctcg catcatttac
    15061 gtaataacag atgagagcta ggtagaggga aacaacacca tatacgacaa aattcagttt
    15121 ttgatgcctt tgtttgagaa attcaatctt cactaaatca agcaattccc tcacctcctg
    15181 ttatccgctt aaagtaatcc tctaaacttt cattgttttt ataagaatat tcttttagaa
    15241 ctattccgtt atcttttaag gagttagata cgactgcaat gtcaaaagta ggtgattctc
    15301 cctgaagttc aagttctata tccgaaagaa tactaatctg ttcttgcaga tttatcctgc
    15361 aaagcacttc cttagcttga ggagcatccg aaacaattag gtggattttc cttttatctg
    15421 caccatctat taattcctgc atagtctttt cagccataag gtgggcatca tgcagtatcc
    15481 caactctatc tacaagcttt tcaagttctg aaataatgtg actggatatt aaaatcgaaa
    15541 tgccatgatt ggtactgagt tcctttagat aacggcgcat ttcaaggata ccaataggat
    15601 ccaaaccatt tgttggttca tctaatatca gaattttcgg ctggtgcata atagcgttag
    15661 caattgctaa cctttgcttc attcccagag aatactgctt gaatagtttt ttattttccc
    15721 catctaatcc tactacttgt aaagcttgct ctacctgttt tagcgaaatt cctctcaatc
    15781 ttgcaaaaat agagagattt tcaggtcccg ttaaattagg ataaaaagaa gcactgtcca
    15841 ataccacacc gatttgagat agcaaatcct tagaaaattc acctaacagt ttttcagata
    15901 gaatattcac ttcaccacta tccatagctg tcaagcctaa aatagccttg ataaaggttg
    15961 tcttaccagt accatttctt cctagtaagc catagatttc tccctgtctt aatgtaaaat
    16021 ctatcctatc taagacaatt ttcccatcat aggattttga taaattaaat gtctgtatta
    16081 ctggatttct catttttctc ctccgaacat tcgtacaccc acattaagag atataataaa
    16141 gtagttcctg tataactagt tagttatatg agagggtaat agggtatatc aaacttacaa
    16201 gctcccttta accccttcaa tctgtggcat gatccattgt ataaatgtta cttcacaaaa
    16261 agtttaacaa atcaatccgc cagtcccaga tcaacttctt tagttgttgc agcttgttgt
    16321 ataattctcg attcccagat atattgtgat tgatttacag gttctttgta aaagaaaccg
    16381 cttccaaaca atcctaaaaa ggacaacata aaaatgattt tacgaaactt tgctaaaata
    16441 ctcatattaa ccaccttttt cttatcttta cacttgtaag tgtactactt taaatattat
    16501 ttgtcaataa aaaacaattc tttttatcat tttttttttg ttttattttt ttatgactat
    16561 ttttgcatta gaaagttgaa aaatagagat taaaagtata taattaatct taaatttatt
    16621 taaagagggt tagagatgac catattatct gataaactaa aatccaagag aaaagaaaaa
    16681 ggtttctcac aaaaaacact ttctgaagga atttgtgagc aaagtcaaat cagcaaaata
    16741 gaacgtggca actatatgcc tgctgctgat ttactctata aacttgcaaa tcggcttcaa
    16801 gttcccttag attatttttt cgatgaacag attgaaatga cttccaatat aacaccgttt
    16861 aagaaattag cagaaaaatt acttgaagat cgtaattacg aggctttaga atacctctta
    16921 aacttagaaa aagaaaagtc tcagtatcta tctactgagg atgaatttta tcttctatgg
    16981 attcaagcga ttatcctttt ctacttacat agttccaaag atgaagctat cgccaatcta
    17041 gaaaacgctt tgccaaagct ttcggtcagc tcatctgtgt atcttaaact tctcaatact
    17101 ttatctaatt tttatttttc tgtaggacgt gatgcagaat atgaagaaaa taactcactt
    17161 cttatcagtt tgtatcagga aaaagattta aatcaccaag agtatttatt tggttatatt
    17221 cgagttaaac ataattttgc ctattattta cactctaaag gtaaggagtt agaagctgtc
    17281 caagaagcct tagaaaccat tgatttttgt aaacaaaaag agaccagcta tcagctagca
    17341 cctcttttaa ctatcgttgc aaatgccgga aaagattttt taaagcacga tgaaattctt
    17401 gactattatt tacaggctcg tgatatctgt aaaatatacg agcacaagct cttgatggct
    17461 aaaattgacc attttttgaa agataaggat aggtgacttc gatcgtaata agttataatt
    17521 accaattaat tagaaacata aaagtggagg gaaactaatg tcgttttctc cacttttgtt
    17581 aatatcccct cttccacttg tatcctgccc agcatgctaa agcaagtaaa actaaattaa
    17641 agatgataaa gaaagtcgta aaaccaaata atccattttg agctaaatct gccgtgtaaa
    17701 gttcagtttc tgtaaagaga agataaattc catagacctc cacgaaaata aggaaactga
    17761 caaaaccaat caggaaaagt ccactggcaa taagaaagag tctccataaa agaatgagaa
    17821 ttcctcctac tgctaaaaaa attactggga taaggagtaa atcattcatg actttctcct
    17881 ttctagtcaa tcaattgacg ataatgggtg gcaagagagg aatcaaactc ttctagtttt
    17941 tgaaccaatt ccagatagtc ctctttttca tattcttcaa agtccacacc tcgatgattc
    18001 tgaagagcga tttccaattg actagtgagt tctcgtatag aaaagctgta atcgcctgtc
    18061 acttcctcat aatgttcctt tagctccttg taggcttggt attcttcagg tgtttgaaat
    18121 ccctgtacca aggcctcttc taattgataa taggtatctt ccatcataat tgttacctcg
    18181 tttctttcta tctttatttt accgctcttt tcttttcttg tccgctattt gtatctattt
    18241 tttaatctaa ttcaaaagaa agttgttcct gcttttcgtt tcctttttca tggaattgtc
    18301 ttaaggcctg atctataata tctaaatccg tttctgtttc aatcaatggc gcgagtacat
    18361 cgtattcggc cttttttgtt tgataatcct cttcctttgg aaaatttttc tcaatttcta
    18421 ccttagcagt agtccattta tcctgtaatt catccaataa gttctgagtt ttcacttggt
    18481 cctctttaat gtgatcaatc gtatgctgaa gcctttgaat ggtccccaaa ggagaataca
    18541 aatctaaact gacagaatac tgattttctc ctacaatctt aacagagaag gtttcaggaa
    18601 gaggttgatt tgttggaaga ctaagcattt taatgtcaaa tcctcgatag cttgctaagg
    18661 tacgaaattc tttgctgtca gcttgattat gacggataag acggtgtagg gattcccctg
    18721 cttcagctcg ttgctcaaaa gcttgtttgc ctactgtcat agaaaatgcc tggtctttcg
    18781 acatttcaga ctgttgaatg tcgccttcat acttgcttaa tcgtttctca agaatgggca
    18841 tattttcttc acagtaagag attgtatgac gatagtgatc cttgctgcgt tgaaaggcgc
    18901 gtctttgatt ttctaataga gttagatcat tctctaattc catcttatat ttgagataag
    18961 gattacctgt tgctagtgcc ttaaaatcag aagctgtcat ggtctgctca tcaatgtctt
    19021 ctgcagcacg aatcggctcc ttagaagtca taatctgctt aatataacgg agtttgttct
    19081 cctgagttgc ccatagataa ttatcaaacg aacctttggt aatatagtgg taaatatcca
    19141 cttccttgtt ttcatttccc tgtcggataa tccgtccatt gcgttgctga atgtcacttg
    19201 gtctccaggg gacatccagg tgatgaactg ctttcatctt gctctgaaca tttaaacctg
    19261 ttcctccttt ttcagttgag gcaaggagaa tccgcacttc tcctgcattg acctttcgag
    19321 acaaactatt cttcttttca tcactattgg catcatgtac aaaggcaatt tccttactag
    19381 ggattcctct atcaactaat aaagccttta tttcagaata tacatcaaag ccattatcct
    19441 ttttcttagg tgttccaata tctgaaaaaa tcatctgagt agccttattt tccattccct
    19501 cacgataaat tctctcaaca ttatccacta cctgaagcag tttatgattg tctgctagac
    19561 tataactaga gtccaacaaa cgcatatcaa tagctagttt tcgtgcctca cccgtaatct
    19621 ttaacatgtt atcctggctc ggatcaactg tcccacattt gaccatatct gacctcataa
    19681 ctaattcttc taaatagagt ttctgatttt cagttaattc actctcaata gggataatat
    19741 gagcttctgg aacaggtaaa tccaacatat cttgtgtttg aatgtcggct gtttctttat
    19801 agattttcat caactcaggt agattgacaa actttttaaa tcgtttctta ggttggtact
    19861 tatcccctgt aggagctaat tccatagagt tttgaatttc tccaaaagca cctacccaag
    19921 agtcaaaata atcaacttga tagcgtttta agatatctgg ttgaatatag ttcatcatag
    19981 tatacaactc actaatagaa ttagaaacag gtgttcctgt cgcaaagaca atatttttaa
    20041 aatcatgttc ttcctgaatc tgtcgaacct tcatctccat atccacgttc ttcttagagg
    20101 ttgtattggt aatacctgct acattcccaa gtccagtaat tggacgaata tttttaaagt
    20161 gatgtgcttc atccacaaag agaaaatcaa ttcctaagtt ctcaaaatca ataaaactat
    20221 cacgattgaa acgttggagt tcttccaatt gtttctctag accacttatt gattgctctg
    20281 cttctttaac ggtgtactta ttttcagaat gtgttttaat ctctcgtagt tcattgagtt
    20341 tgtcctcgat ataattcatc tgtctttcct tactgacagg gattttttca aattgagaat
    20401 ccccaatgac aatggcatcg taatctcctg taatgatacg tgacacaaat tgttttcttc
    20461 tcgccttcac aaaatctttc ttagtggtca caaagacttt tttagtaggg aaaaatttca
    20521 tgatttcttg gccaaactga gcagacaaac tagagggcac cacatacaag ggcttatgaa
    20581 ccatccccaa ctcctttaat ttaaacccag caccaagcat ggtcaaggtc tttcctgaac
    20641 ctacctcatg agctaataaa gctctttttt cttctacgat tctttgaata gcattctctt
    20701 gatgaggacg aagactgatg ttttgtgcca agccatcaat gactagatgg ctaccatcat
    20761 actctcgact aactgttcga ttataaagac gattatagct ttcctcaatg acctgttgga
    20821 cttctggata ccgtgagaca aattcttgaa agagctcttg taaatgctgc tcttttgctc
    20881 ttagaacaga ggttttttcc aaatctgtga tagtcttttt cttttcccct tccgtaacag
    20941 tcatggtaat cgtcggttgg ttcgaattaa gtaaattctc aaaaatcttt cttcctgtat
    21001 cataacgtga cccactaact ccaagactac tatctttggc acttggatag cgataaacaa
    21061 atgatgtcct taaatgaacc tggccatcga caggattcac ttcaatgact tgttcaacat
    21121 ctggcgaaga caattcaaat tcacgattgg taaaacattc aaaggcaaat ttaccataaa
    21181 cggattgagg aatccaacgt gaccctattt tgaactcaat atctgctaga tgaatccgtg
    21241 gagggcgaac agattctaac aaatctaaag catgagacca gtcaaattct tggttgtttt
    21301 catctactaa tagttgaact acttctatct tattgagaat atctcctgac aaaaactggt
    21361 tcttagaaag atattttctt tcccctctta aataactttc tggatccatt aaaacctggt
    21421 cacctaactc atctaaaata gcagcttggc tatgttcggg ataaattgat accatatagt
    21481 ctaaatcaac tcctctacca tccgataaac tggagtttaa ggcatctaaa gccgttgata
    21541 ctcttgtaat ctctctctct ggtctaacca atgctttctc aaaggctaaa gattttttat
    21601 attttacttt ctggtcttta gaatcgatgt attcatcttc taaacttgct agtaaagaat
    21661 acttatcgtc actatcaaat aagttccgat tgactgaggc attcaagtat ccaaattgac
    21721 ttacaaagcg gtcatagtta tgattgagtt tactaagtaa cacctgaaat tctgttcgac
    21781 tgtaatctgg atgacgttga atttcaatta aggattgata ggtctctctc aaatcaacca
    21841 tgcccttaat gcgactaata tccttatccg ataagggact ttcataaaag acagtttttt
    21901 tgaacagtcc cttatatttc ccccttttac tcgcttcttc tgacttgtaa acatctagtg
    21961 cttcctcatc tgtcaaatga agttgcacga atcggtctat tttatgttca gacaaagaac
    22021 tgtcccaagc tttaaaatct cccttctcat ctacataata actaatttcg tctacttttg
    22081 aacttttccg aatgccatgc gtatctcggt aataaatttg atttccctca tatccaaaag
    22141 aatagagcgc taagtcctca cgtatacgac ttgggatcga attatccact tcttcttgga
    22201 taaaaacagg tgctttcaaa gaattgtcaa tttgtttagg tgcttccaca ttctcgaatg
    22261 ctttcattat atcagtagat aatgtttctg attccccctt tacattgagg gttcctccat
    22321 taaaattacg tacttcatat tcacccaaaa cttgtgtgtt gtatttccca tcaaaataag
    22381 gattgatcca gacacgctta tcttcctcaa agggaataga gccactaaag acaagttcct
    22441 cctcattaag attctttgct tgatcctttt gaaagaagag gagatctgtg gtcactcgag
    22501 tacctgcaat cgttttaaaa gccgtatccg gcaaacgaac accccctaaa aaatgagtgt
    22561 tggttttaat ctcttgtaag acattatctg tccgcttatc cattgtccca atagatgaga
    22621 taatcgacac ttgtcctccg tctcttacta aatcaagtga gtgtttgaca aagtaatcat
    22681 gaatcatata aggtttatcg tagtttttat cggcaatgcg aaaatttcca aaaggaacat
    22741 tcgttaagac taaatcaaaa ctattatttt gatagggaac ttcttcaaat cctcgcactt
    22801 caatatgggt attggggtgg agttgttttg cgattgcgcc tgtcacactg tctaattcaa
    22861 ccccatagag ctctgattta tctcgtatac ttctaggcat cgccgcaaag aagttcccag
    22921 tccccataga aggatctaat atccttcctc cctcaaaacc atcatccagt aatttttgcc
    22981 aaatctggcg aataatcatt gggtttgtat aataggctgt gagagaactt tgtttcatgg
    23041 tggagtattc tgatttactt actaaactct taagagttaa acgttctgct tcatactttg
    23101 gattgagttc atcgaaaaat tcattagcaa gaccacccca tccaacatac ttggctagta
    23161 gttcttgttc ttctggactt gcttgtcgtc tctctttttc taatctttta acaagatcaa
    23221 ttgcggcgat attcgtttca attttttctc ga
//
