LOCUS       NZ_CP011509            22351 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Archangium gephyra strain DSM 2261 chromosome, complete genome.
ACCESSION   NZ_CP011509
VERSION     NZ_CP011509.1
KEYWORDS    RefSeq.
SOURCE      Archangium gephyra
  ORGANISM  Archangium gephyra
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Archangium.
REFERENCE   1  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Genome assembly of Archangium gephyra DSM 2261
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) Protein Science and Engineering, Institute
            of Microbial Technology, Sec-39 A, Chandigarh, Chandigarh 160036,
            India
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: HGAP Pipeline v. SMRT v2.3.0
            Coverage                          :: 79.3
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001027285.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:37:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,001
            CDSs (total)                      :: 9,898
            Genes (coding)                    :: 9,822
            CDSs (with protein)               :: 9,822
            Genes (RNA)                       :: 103
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 28 of 76
            Pseudo Genes (incomplete)         :: 45 of 76
            Pseudo Genes (internal stop)      :: 6 of 76
            Pseudo Genes (multiple problems)  :: 3 of 76
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9383721
            Orig. end                         :: 9406072
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22351
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="thioamitides"
                     /region_number="42"
                     /rules="((YcaO or TIGR03604) and TfuA)"
                     /tool="antismash"
     cand_cluster    1..22351
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and TfuA)"
                     /kind="single"
                     /product="thioamitides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22351
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12351](-)"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12351)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
     gene            1314..2021
                     /locus_tag="AA314_RS36625"
                     /old_locus_tag="AA314_07497"
     CDS             1314..2021
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF022041.4"
                     /locus_tag="AA314_RS36625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07497"
                     /product="glutathione S-transferase family protein"
                     /protein_id="WP_047859298.1"
                     /sec_met_domain="GST_N_3 (E-value: 1.7e-06, bitscore: 27.5,
                     seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLHKGPAAFGVSDISPFCLKLETYLRMAGVSYTARAADFGKAP
                     KGKIPFIEEEGSFLGDSQLIIEHLKRKHGDPLDAKLGAAELVQGHLVRRVLEESVYWHI
                     IHERWVTPEGWRIYKPVFEGFFPRVVGKLASPMVRRGVIKASHTQGLGRHRPEEILEMG
                     KADVSAVAAVLGDKPFLLGENPTSFDAALYAFIVSIIAFPLDSPLRKYTQGQQNLVRYC
                     ERVQKRYFANGQK"
     misc_feature    2162..2177
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            2163..2540
                     /locus_tag="AA314_RS36630"
                     /old_locus_tag="AA314_07498"
     CDS             2163..2540
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS36630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_07498"
                     /product="hypothetical protein"
                     /protein_id="WP_147333093.1"
                     /transl_table=11
                     /translation="MRRMLVSCMAAGAVWLSGCANCEQLQEAATELVSHYAQCSPGDTC
                     QKIDLLALAGGQNCLGAFQCFGAVNMRANLTEFQRRARTLAQQASIVCQPGECVTASCL
                     DPRELIPVCDTALGQCVLVPR"
     gene            complement(2547..3917)
                     /locus_tag="AA314_RS36635"
                     /old_locus_tag="AA314_07499"
     CDS             complement(2547..3917)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002614202.1"
                     /locus_tag="AA314_RS36635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07499"
                     /product="FAD-linked oxidase C-terminal domain-containing
                     protein"
                     /protein_id="WP_047859300.1"
                     /transl_table=11
                     /translation="MSVDLLRELAAVLPPEALVTDPDVLESHRRDQAGWALAGVPRVLV
                     RPGSTTEVQAVLRVASAHRVPVVPRGAGSGLSGGANAVDGCIVLSLTRMNRILELDRRG
                     LYAVVQPGVINGALKSAAAELGLWYAPDPASWEFSTLGGNLATNAGGLCCVKYGVTGDA
                     VLGLEAVLADGSVVRTGGRMVKNVAGYDLTRLFVGSEGTLGIITEATLKLRPRPPRATT
                     LVASFPTLVGAGAAVTEIMAELRPSLLELMDRTTVRAVEAARPMGLDVNAAALLLARSD
                     AGGEQGVAESTRMAAICEAVGATFVAHSSDEAEGELLMGARRFAFPALERQGSTLLDDV
                     GVPLSRIPDLLAEVERIAGQRGVLIGTFGHAGDGNMHPTIVFDPNDPDAVARARAAFDD
                     ILHAVLELGGTITGEHGVGSLKRPFIARQLGPETHRLHLTIKSAMDPLGILNPGKLL"
     gene            complement(3975..4871)
                     /locus_tag="AA314_RS36640"
                     /old_locus_tag="AA314_07500"
     CDS             complement(3975..4871)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002615281.1"
                     /locus_tag="AA314_RS36640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07500"
                     /product="hypothetical protein"
                     /protein_id="WP_047859301.1"
                     /transl_table=11
                     /translation="MPSLRHEAFLELFRNRPALAAELLRDALGVEVPAYAEARAESAEL
                     TQVVPTEYRADLVVQLWEDTPRFAIVVEVQLSADEEKRYTWPVYLTHMRAKLRCPTVLL
                     VVAPDGPVARWGGQPVDLGHPGFVLRPCVAGPERIPVITRPEQAREAVELAVLSAMAHG
                     QGEKGAAIADAVLPGLVGIDEERARFYFDLVMGSLNDAARTALEALMSSGTYEYQSEFA
                     RRYFAQGRQEGRQEGRQEGRQEGEVTALLEVLGARGLQVDEQSRQRIAACTDLEQLKRW
                     LRKAVSVQSVQELFESA"
     gene            complement(4956..6842)
                     /locus_tag="AA314_RS36645"
                     /old_locus_tag="AA314_07501"
     CDS             complement(4956..6842)
                     /GO_function="GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002628009.1"
                     /locus_tag="AA314_RS36645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07501"
                     /product="OPT family oligopeptide transporter"
                     /protein_id="WP_047859302.1"
                     /transl_table=11
                     /translation="MSPSATPSPQQLKLTPEPPHPAAPSAGTQDPERYWLENVYKGAEH
                     QLTVRAVVAGMLIGAVMCLSNLYVILKTGWSLGVTITACVLSFAAFSALRAVGLVKKEV
                     TALENNAVGSVASGAGYMTGGGNMAAVPALLMLTGTLPSAGWLVAWFAVISTMGVFAAI
                     PIKRQLVNVEQLPFPTGTATAETLQALHGHDEGSRGKARYLGLAGLVGAVIAFWREGRA
                     SWLAWNLPSKLSLPFTIMGKPAGAWTLSFDLSLLLIGAGALVSFKTGWSMLLGAIFTYG
                     FLAPEMVSRGVIPEVTYKAINGWALWTGASVLVSSGLLSFAFQWRSVAKSFKALSGLFG
                     KNTEEEKDVLADVECPPTWFPLGFLVLGPIVVGLMAYLFQIPWWAGVIALPLSVVMGVI
                     AARVTGETDTTPTKALGPVTQLLYGALLPGNLAANVMSANATGGVGLHSADLLTNLKTG
                     WLLGANPRKQFIGQLFGVLAGAAVVVPAFNLLVPSADVLGTEEFPAPSSLVWAGVSKML
                     VNGVNSLHTSARIGAVCGLALGVALVLLDRWAPKKAKPFIPSASGLGLSIVIPGASSIS
                     FFIGAAIAEVLRRKKAKLAEATVLPVSSGFIAGESLMGIAVAMLKAFGMMPK"
     gene            complement(6905..7387)
                     /locus_tag="AA314_RS36650"
                     /old_locus_tag="AA314_07502"
     CDS             complement(6905..7387)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002628011.1"
                     /locus_tag="AA314_RS36650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07502"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_047859303.1"
                     /transl_table=11
                     /translation="MKVSKDSVVSLEYRLHLGDGQVVDESEPGQPLAYMHGRGQIVPGL
                     EGQLEGMAAGESKKVVVPPSQGYGEHDPRGLQEVPREMFPPNAQLQPGLTISAQTADGD
                     VIPITIRELKGEKVVVDLNHPMAGKTLHFDITVREVRAATDEEKEHGHAHGPGGAH"
     gene            complement(7465..8742)
                     /locus_tag="AA314_RS36655"
                     /old_locus_tag="AA314_07503"
     CDS             complement(7465..8742)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020480703.1"
                     /locus_tag="AA314_RS36655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07503"
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="WP_047859304.1"
                     /transl_table=11
                     /translation="MKQHQKMLLGIVIGTVAGIAANLAAGGTPWLEWVVANITGLAGQL
                     FLRLLLMLVVPLLFSALVMGVCELDLKQLGRLGLKTMGYTVVISSIAVLIGLVLVNTLK
                     PGVGLSDEARALAMKGTSVQAAPAPSSTSVPSLIAAMVPSNPLKAAADGDMIALIVFSL
                     IFGLGLALTDTPAARHLRETIQGLHDVMMKLIDGVLKLAPIGVAALLFSMMARLGMGVL
                     MQVASYVGVVLLALGLHMFVVYSLSVRFLGGRNPVAFFRDCRLAIVTAFSTASSSATLP
                     TALKVAEENLKLPRNVSRFVLTAGSAMNQNGTALFEGVTVLFLAQVFGVQLSLPDQAVV
                     MFICVLAGIGTAGVPAGSIPVIAMILGMFKIPPEGLALVLGVDRFLDMCRTTLNVTGDL
                     AAAVYVSRGEPNVDTEAELEPRSSAS"
     gene            complement(8801..9634)
                     /locus_tag="AA314_RS36660"
                     /old_locus_tag="AA314_07504"
     CDS             complement(8801..9634)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006306 - DNA methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002628014.1"
                     /locus_tag="AA314_RS36660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07504"
                     /product="DNA methyltransferase"
                     /protein_id="WP_082175541.1"
                     /transl_table=11
                     /translation="MNPHDELETFRCVRADSREPGGYRAVLGEAKATFLHTDPPYCLLT
                     RRRKGGDLRDPRANKKIDRNPIVRFETVRDYRVFTEEWMTHAVAHLTPDAPMAIWTNLL
                     GKEPILAVARSLGFHHLRGEYVWGKRTTEKNANEQLLRVYEVALVLSRTPAPELEPGGL
                     PTVWAVVGGYDDDAEAARWGNHPHHKPFSVLEPLVRTWSRPGDWVLDPFAGSGSMPAAA
                     LRLGRRAACLEVEPEWAERVNRRLRETAGERARGAGVQRETAATADDVSATGNRR"
     gene            complement(9666..9908)
                     /locus_tag="AA314_RS36665"
                     /old_locus_tag="AA314_07505"
     CDS             complement(9666..9908)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002613773.1"
                     /locus_tag="AA314_RS36665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07505"
                     /product="hypothetical protein"
                     /protein_id="WP_047859305.1"
                     /transl_table=11
                     /translation="MTRICQDEVGRCDFIDVLEEAVLRHRPVAVQLREGEAFIDEVLDV
                     VTERGDDFAVFRSHERVPVGDILAVTRAVAPEARW"
     gene            complement(10001..11188)
                     /locus_tag="AA314_RS36670"
                     /old_locus_tag="AA314_07506"
     CDS             complement(10001..11188)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002628015.1"
                     /locus_tag="AA314_RS36670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07506"
                     /product="TfuA-like protein"
                     /protein_id="WP_047859306.1"
                     /sec_met_domain="TfuA (E-value: 2.4e-44, bitscore: 149.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRRPAHHPDDLLVFLGPSLPEEDALALVPCRVLPPARQGDVWRA
                     LSLHPRAIALVDGVFEAQPSVWHHELLAALDAGVAVFGGASMGALRAAELARHGMVGVG
                     HIFEAYQRGELVDDAEVALLHADAEHGFRALTVPLVNVRHAARQAQGAKVLAPREAQAL
                     VDAAAALFYQDRTWPRVLAAVGEAWRPATRAKWDAWAAGGFEDLKREDARACLQAASAW
                     IASGAEAPVRARTGRPPPSSYVRRRRLMEGLCETEGGLVSSEEVLGGLRAAPEARELAE
                     AGLRRALLAGQARSLGLLATEEEVIRAEDEWWELLGVPPKERDAYLAACGLDAHEVWRL
                     CEDRALERLMLEHASRVLPDGPSWDEALATEARLRGHWVEEAQRLGAPKRGRRKR"
     gene            complement(11185..12351)
                     /locus_tag="AA314_RS36675"
                     /old_locus_tag="AA314_07507"
     CDS             complement(11185..12351)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002628016.1"
                     /locus_tag="AA314_RS36675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07507"
                     /product="YcaO-like family protein"
                     /protein_id="WP_082175542.1"
                     /sec_met_domain="YcaO (E-value: 6e-59, bitscore: 199.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALPTAVPLTSSFLDRLAHGLGVTRVARVTGLDRAGVEVAAAVRP
                     GGYVLQVCNGKGLDFQAASAGALLETAELWGAERVPMERLVWGSMDGLETRGRAVWGAE
                     ELGTRGGVVISRLWSREMRYAWCEATELQSGQPVLLPAQGVYCPPTGAPALGPVSVQWT
                     SNGSGAHPERARALLHALLEATERDQLARILPEGWSEEVLLSRLLRPGDLEQGAPRTAA
                     LARALGERGFAVYLFDLTPGARTPRAAGLPVGAALLVDREEGPVPLAAGYACGLGRDQA
                     LLGALLEAAQSRLTDIHGAREDVAAGDREATLALAAACAEVRPRRAVTSMPDVSGEVSS
                     PEEAVREVLARLGKAGFRRAAAVELETPLPGLHVVRVVVPGLRVSELL"
     gene            12435..12902
                     /locus_tag="AA314_RS36680"
                     /old_locus_tag="AA314_07508"
     CDS             12435..12902
                     /EC_number="1.11.1.24"
                     /GO_function="GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014398465.1"
                     /locus_tag="AA314_RS36680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07508"
                     /product="peroxiredoxin"
                     /protein_id="WP_047859308.1"
                     /transl_table=11
                     /translation="MLDVGQAAPDFTGTDCWGRTFSLSALRGRRVVLFFFPKAFTLACT
                     EETRHFRDNHERIQALGAELVGVSVDTVKTQCEFAEKEDIHFSLLGDEGRTISQAYDVL
                     WPVLKVDRRVTYIIGPDGRVESVIRHEVRVYKHLDDVLRYLSEHPLPSAGA"
     gene            complement(12899..13480)
                     /locus_tag="AA314_RS36685"
                     /old_locus_tag="AA314_07509"
     CDS             complement(12899..13480)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002628017.1"
                     /locus_tag="AA314_RS36685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07509"
                     /product="TIGR02265 family protein"
                     /protein_id="WP_047859309.1"
                     /transl_table=11
                     /translation="MAMDSAAARIKGSVLITRLNLLMKQGGTGRLQQVLQRLPPADRKV
                     LESVIMPIGWYPLELNSRLDAAIADALSPRDRNKAFVEMGRASAEENLNGPHHVFIRKG
                     DPHFLLSHSPEIYRLYYAVGSRTYEKTGPRSAVVRTVGAESVTEADCLTIVGWYERAIE
                     MSGGRGVRIEQKKCRARGNGHCEYDCAWEL"
     gene            complement(13598..14113)
                     /locus_tag="AA314_RS56170"
                     /old_locus_tag="AA314_07510"
     CDS             complement(13598..14113)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS56170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_07510"
                     /product="hypothetical protein"
                     /protein_id="WP_047859310.1"
                     /transl_table=11
                     /translation="MAEMMGTDIGTQILNAVQGLGVRIDRLETQVADLRTQVAGLDSRM
                     VRQEKLTERLGAELERQRAELERQRAELERQRAESERQWAEFRTWRDGMNREFHHMRGE
                     FQSMREEFRQIRVDFRQMLADMQEGFSRLHARDELTATTVVMMAAVLRRPTELGEDLEK
                     RLRELQPH"
     misc_feature    14190..14205
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.43"
                     /tool="antismash"
     gene            14318..14926
                     /locus_tag="AA314_RS36695"
                     /old_locus_tag="AA314_07511"
     CDS             14318..14926
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002628020.1"
                     /locus_tag="AA314_RS36695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07511"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_047859311.1"
                     /transl_table=11
                     /translation="MKALETSLALAEAATEPSDEALCRAFLAGDEAAFGTLVERHRALV
                     FSLLRRSTRRPEDAADLAQQAFLRALEASRRVFARWSPSGPAPFRAWLIRIALNLAKNH
                     ARQGRRWLQAVHLPETESPEESAHESLERTERERQVRAAVLTLPRRQREVLTLRVDGGL
                     GFRDIAETLGITETNAKVNFHHAVKRLRAQVAEPSEEER"
     gene            14926..15471
                     /locus_tag="AA314_RS36700"
                     /old_locus_tag="AA314_07512"
     CDS             14926..15471
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024881.4"
                     /locus_tag="AA314_RS36700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07512"
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="WP_063796917.1"
                     /transl_table=11
                     /translation="MAACQDNEELLTLFAAGALEPEEEARVRAHLDTCATCRAEAEANQ
                     EVLGLAALPPPSVKEQAMVAALPRTTVGAWRRAQVQQAARMRTAGALMAAAAVVLLVLG
                     PVLQRRVATPPTPTPPVEAPANTPEEDAVALEQWALADPLADALDLSEADLEEPESDEL
                     LDSELDDFFSDTNPGESL"
     gene            15471..16022
                     /locus_tag="AA314_RS36705"
                     /old_locus_tag="AA314_07513"
     CDS             15471..16022
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002628022.1"
                     /locus_tag="AA314_RS36705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07513"
                     /product="hypothetical protein"
                     /protein_id="WP_211276570.1"
                     /transl_table=11
                     /translation="MKPFRLAVLTLCLLPLASLAQTPEAKEAAERAERQTRLMRVVGLA
                     EELGLEEAQALKMADTMRQFDERRRPLVEQVQESAQVLRKAAQGDASTQSQVDQAVQRV
                     FDARTQLTALDRDMYQALARDLPPQKRAQLAIFMARHDGKMKMEKMLRKADREGRREER
                     EKRRQERMQRMQQRMQERDR"
     gene            complement(16031..17002)
                     /locus_tag="AA314_RS36710"
                     /old_locus_tag="AA314_07514"
     CDS             complement(16031..17002)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014396600.1"
                     /locus_tag="AA314_RS36710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07514"
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase III
                     C-terminal domain-containing protein"
                     /protein_id="WP_047859312.1"
                     /sec_met_domain="fabH (E-value: 1.9e-20, bitscore: 72.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRPSIAFLGLGSALPERVRTSADPIFDRIREAARAQGLSEASLF
                     YGNREHRCLAPDESLASLTAKAGRAALEDAGVRPEQVDRLYGYVSVSEFVSPNALYQVH
                     RELGLGSHALVVPVQADFGNFVMGTVLAWEAMLAGHSERALVAVGAGWTRNVDYAQGHA
                     FGIGDGAGAAVLGAGERLVLVDYAADTFSDEYGAMTMRSRPEAGFTTPVYGLEPSRGVQ
                     AFLNTGMEGPPRLVERLLRKHGLTGDDITLVSHQATRKLLDHWNEKIRPREYLHTLEDC
                     GNMVIASIPVTLARHHRELRTKYLVLFGIGIGAHQVALLVRV"
     misc_feature    complement(17003..17019)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.79"
                     /tool="antismash"
     gene            17118..17756
                     /locus_tag="AA314_RS36715"
                     /old_locus_tag="AA314_07515"
     CDS             17118..17756
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553052.1"
                     /locus_tag="AA314_RS36715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07515"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_047859313.1"
                     /transl_table=11
                     /translation="MSALSLRYVALGDSSAVGVGSRSGGYVEHLFQRLRRTRPGVGLLN
                     LGVSGATSATVLSGQLPKASRSRPHVVSLAVGINDLWRGVEPHQFESNLDQLARGLVAT
                     GAPVVLSNLPDMSLAPIARLATHFLPIQLISARIASFNEAVARVVARHGLLGVDLHGPS
                     LQELPGSTDYFSADGFHPSDTGYQRMAEHFWPVLLQAAELGASTERATG"
     gene            complement(17776..18588)
                     /locus_tag="AA314_RS36720"
                     /old_locus_tag="AA314_07516"
     CDS             complement(17776..18588)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (19-254). E-value:
                     1.8e-27. Score: 88.4. Matches aSDomain:
                     nrpspksdomains_AA314_RS36720_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624812.1"
                     /locus_tag="AA314_RS36720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07516"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_047859314.1"
                     /sec_met_domain="PF00561 (E-value: 4.3e-20, bitscore: 71.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.3e-20, bitscore:
                     72.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQAIRKRNNVQVLGSGRDTLIFAHGFGSEQSAWRHQVKAFQDRY
                     RIILFDHVGCGGSDFNAYSPQRYSGVHAYAEDLLELCEELKLSDTIFVGHSFSGMVGVL
                     AAMVEPRRFRQLVFVKSTPRLLDDPESGYVGGFSRAELDAFFDAMASSYHTWASGFAPL
                     AMGNPERPELGQEFARTLSSMRPDIALALARTIFQYDHRLDLPRLKVPTLIIHSGEDLA
                     VPNPVGEYMARRIPLARMMTIAARGHLPHLSAPEAVNRAIDTYLHATA"
     aSDomain        complement(17827..18531)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AA314_RS36720_Abhydrolase_1.1"
                     /evalue="1.80E-27"
                     /label="AA314_RS36720_Abhydrolase_1.1"
                     /locus_tag="AA314_RS36720"
                     /protein_end="254"
                     /protein_start="19"
                     /score="88.4"
                     /tool="antismash"
                     /translation="TLIFAHGFGSEQSAWRHQVKAFQDRYRIILFDHVGCGGSDFNAYS
                     PQRYSGVHAYAEDLLELCEELKLSDTIFVGHSFSGMVGVLAAMVEPRRFRQLVFVKSTP
                     RLLDDPESGYVGGFSRAELDAFFDAMASSYHTWASGFAPLAMGNPERPELGQEFARTLS
                     SMRPDIALALARTIFQYDHRLDLPRLKVPTLIIHSGEDLAVPNPVGEYMARRIPLARMM
                     TIAARGHLPHLSA"
     misc_feature    18730..18746
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.43"
                     /tool="antismash"
     misc_feature    complement(18731..18746)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            complement(18743..20542)
                     /locus_tag="AA314_RS36725"
                     /old_locus_tag="AA314_07517"
     CDS             complement(18743..20542)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002611153.1"
                     /locus_tag="AA314_RS36725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07517"
                     /product="hypothetical protein"
                     /protein_id="WP_047859315.1"
                     /transl_table=11
                     /translation="MVGFSTALLATVLASLAPMVPVSGGNALTLPAQRHAVRIDTGSGR
                     PPTWLLTVQQEGAEGRGLSFFRSDDGGRTFRFAAAIQPDASHADRAEVLAVGRDVALVY
                     SFEAPRLTASRRHDVYFQWWRYRPETHDWAPQPAVRVFDADDTTAYSRALLARDSRGRL
                     WVQAFRLDSDGGSTAVLSVSTDGGASFQRQANLGRVKRRGGGRLLSLGSKLVFVYAMHD
                     GFEPTRLRLRDDADPLDTWSAVRDAFSEGIYHGAALSAVADGRGGMHLVYKDESERLYH
                     RHFNGSTFGPRTLLEGSRDWAMQAATTRIGDTLYVFYNTMREPNVSYEVRARVLKDGRF
                     SEPVVLDSRRTYKGYPNALETLPEGTSEVPCFFGDAPDANSRGYVSRVSLAVPGGGGGD
                     DAPPDEDEDAPGSEPQPGELLFGDTFPRTSSSSLGSDWKLSGLWLTDGRRAVSDLDNPN
                     GDNLAFALPSRCDDCQVQARLQAFGADEAGLVVRAEADARYALVLLPQGRLQLRRYGGG
                     GFIVLGETASGLAAPWEAATLSLSVWGAGPVRLSASVEGQVRLRVTDDDPAALTGEGYA
                     GLATPIAGVWFDDFLVRALGTGP"
     gene            complement(20634..21749)
                     /locus_tag="AA314_RS36730"
                     /old_locus_tag="AA314_07519"
     CDS             complement(20634..21749)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016450659.1"
                     /locus_tag="AA314_RS36730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07519"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_047859316.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.9e-10, bitscore:
                     40.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.4e-16, bitscore:
                     58.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSVESIITEVIEPKAMEVDRYGVYPRAAMEALGKAGLLGLLSAR
                     DVGGRGEGLRAAATMVEQVGTACGSSGMVLCMHFCGAAVIEQHGPRDIREAIAAGRHVT
                     TLALSEAGSRSHFWAPVSTALAVPEEGTVRLDAEKSWATSAGQADSYVWSSKPVEAKGM
                     STLWLVLGNAHGLSFPVAFDGMGLRGNSSSPIVARDVRVPRSAMLGKDGGGFDIMMGNV
                     LPHFQVLGSACYLGIMEAATRKAAAHVTKTRLLHTGQSLADLATIRAYLARMRMKTDLV
                     RGLIRDTLDALESKREDAQMRVLEVKAAVGELAPEVTELGMRVCGGAAYRKEVGIERHF
                     RDARAVTVMSPTTDLLYDFIGKAMTGMPLFD"
ORIGIN
        1 agcgcttcgg tgtggtgcag gggcgctacg aggagctggg cggctacgcg ctggagggcc
       61 gggcgcggga gatcctcgcg ggcctcggct tctccgagga gatgatggac ggggacgtgg
      121 gcgccctgtc gggcggatgg aagatgcgcg tggccctggc ccgcatcctc ctgatgagcc
      181 cggacgtgat gctgctggac gagccgagca accacctcga catcgagtcg ctcatctggc
      241 tggagaactt cctcaagggc ttcgagggag cgctgctgat gacgagccac gatcgcgagt
      301 tcatgaaccg catcgtgacg aagatcatcg agatcgacgg cggcgagctg acgacgtaca
      361 cgggcaacta cgagttctac gagcagcagc gggcgctcaa cgagaagcac cagcaggcgc
      421 agtacgagcg ccagcaggcg atgctcgcca aggagctgaa gttcatcgag cgcttcaagg
      481 cccgggcctc gcacgcggcc caggtacaga gccgggtgaa gaagctggag aagatcgaga
      541 aggtggagcc gcccaagcgc cgccagacgc tggtgttcga gttccagcag gcgccgcgct
      601 cgggcgacga cgtggccaag ctggagcggg tggtgaaggg ctacggcaag cgccgcatct
      661 acaacggcct ggacttcctc gtgcggcgcg gcgagcgctg gtgcgtgatg ggcgtgaacg
      721 gcgcgggcaa gtccaccctg ctcaagctga tcgccggtga gtccaagccg gacgacggcg
      781 cggtgagcgt gggcggcagc gtgaagatgg gctacttcgc ccagcacgcc atggagctgc
      841 tcaagccgga ccagacggtg ttcgactcgc tggtggacag gttcccccgg gcctcgcagg
      901 gctcgctgcg cgcgctggcc gggtgcttcg gcttctcggg cgatgagatc gagaagaagt
      961 gcaaggtgct ctccggaggc gagaaggcac ggctggtgct ggcgcagatg ctgtacgacc
     1021 cgcccaactt cctgatcctc gacgagccca ccaaccacct ggacatggcg acgaagcaga
     1081 tgctcatcgc ggcgctggcc aactacgagg gcaccatgct cttcgtgagc cacgaccggc
     1141 acttcctggg cgcgctgtcc aaccgggtgc tggagctgac gcccgagggc atccaccagt
     1201 acggcggcgg ctacacggag tacgtggccc gcaccggcca cgaggccccc ggcctgcgca
     1261 gctgaccgaa gggttctgga cgggcctcac ccgggcatgg aggattcccc tccatgctca
     1321 ccctccacaa aggccctgcc gcgttcggag tcagcgacat cagccccttc tgtctgaagc
     1381 tggagaccta tctccggatg gccggggtct cctacacggc aagggcggcc gacttcggga
     1441 aggcccccaa gggaaagatc cccttcatcg aggaggaggg ctccttcctg ggtgactccc
     1501 agctcatcat cgagcacctc aagcgcaagc acggagaccc gctcgacgcg aagctcggcg
     1561 cggcggagct cgtccagggc cacctggtcc ggcgggtgct ggaggaaagc gtctactggc
     1621 acatcatcca tgagcgctgg gtcactccgg agggctggcg gatctacaag cccgtcttcg
     1681 agggcttctt cccgcgcgtc gtcggcaagc tcgcctcgcc catggttcgc cggggggtca
     1741 tcaaggcgag ccacacccag ggcctgggcc gccaccggcc agaggagatt ttggagatgg
     1801 ggaaggcgga cgtctccgcg gtggcggcgg tgctcggcga caagccgttc ctgctgggtg
     1861 agaaccccac ctcgttcgac gcggcgctct acgcgttcat cgtgagcatc atcgcgttcc
     1921 cgctggactc accgctccgg aagtacaccc aggggcagca gaacctggtc cgctactgcg
     1981 agcgcgtcca gaagcgctac ttcgcgaacg gacagaagta gaccgccccg gcaggccccg
     2041 tctgtacacc gagcaacagc gcgctcccgg cctccccgcc gggcgatgcg cgtggggcgc
     2101 cgcatgtcca ggcttcgtcc gctcgacgag cggttgagtc gaggcacgcg ggggtggtgg
     2161 gaatgagacg gatgctcgtg tcgtgcatgg cggcgggggc ggtgtggctg tcggggtgtg
     2221 ccaactgcga gcagctccag gaagccgcga cggagttggt ctcccactac gcccagtgca
     2281 gtcctggcga cacctgccag aagatcgatc tgctcgccct ggccggcggg cagaactgcc
     2341 tgggcgcgtt ccaatgcttc ggcgccgtca acatgagggc caacctcacc gagttccagc
     2401 ggcgagcgcg aaccctggcc cagcaggcct ccattgtctg ccagccggga gagtgcgtca
     2461 ctgcgtcctg tctggacccg agagagctca tccccgtgtg cgacacggcg ctcggccagt
     2521 gcgtgctggt gccgcgttag acgtgctcag agcagcttgc cgggattgag gataccgagc
     2581 gggtccatcg cgctcttgat ggtcaggtgg agccggtggg tctcgggacc gagctgccgg
     2641 gcgatgaacg ggcgcttgag cgagccgacc ccgtgctcgc cggtgatggt tccccccagc
     2701 tcgagcaccg catgcaggat gtcgtcgaac gccgcccggg cccgtgccac cgcgtccgga
     2761 tcgttcgggt cgaagacgat cgtgggatgc atgttcccgt ctcccgcgtg cccgaacgtc
     2821 ccgatgagca ccccccgctg cccggcgatg cgctcgacct ccgcgagcag gtccggaatg
     2881 cgcgagagcg gaacgcccac gtcatcgagc agggtcgagc cctgccgctc cagcgcggga
     2941 aaggcgaagc ggcgcgcgcc catcagcagc tcaccctcgg cctcgtcgga ggagtgcgcg
     3001 acgaaggtcg ctccgacggc ctcgcagatg gccgccatcc gcgtgctctc cgccacgccc
     3061 tgctctcccc cggcatcgga gcgcgccagc aggagcgccg cggcgttgac gtccaggccc
     3121 atgggcctgg cggcctcgac ggcgcggacg gtggtgcggt ccatcaactc caggagcgag
     3181 ggccggagct cggccatgat ctccgtgacc gccgccccgg cacccacgag cgtcgggaac
     3241 gaggccacca gggtcgtggc ccggggcggg cgcggccgga gcttcagcgt ggcctcggtg
     3301 atgatgccga gcgtgccctc ggagccgacg aacagccggg tgaggtcata gccggcgacg
     3361 ttcttgacca tgcgtccgcc ggtccggacg acggagccat ccgccaggac ggcctcgagc
     3421 ccgagcaccg catccccggt cacaccgtac ttcacgcagc acaggccgcc ggcattcgtc
     3481 gcgaggttgc cgccgagggt cgagaactcc cagctcgcgg ggtccggcgc gtaccagagc
     3541 cccagctccg ccgcggccga cttcagcgcg ccgttgatga ctcccggctg gacgacggcg
     3601 tacaggcctc gccggtcgag ctccaggatg cggttcatcc gcgtgagcga gagcacgatg
     3661 cacccgtcca ccgcgttggc tccgcctgac agtcccgagc ccgccccacg cgggacgacg
     3721 gggactcggt gggccgaggc cacacgaagc acggcctgca cctcggtggt cgagccagga
     3781 cgcacgagga cccgagggac acccgccaga gcccatccag cctggtcacg gcgatgagac
     3841 tcgagcacat ccgggtcggt gacgagtgct tcgggcggca ggacggccgc gagctcacgc
     3901 aacaggtcca cgctcatggg cgctgatgct atcgagtgaa cgccaggcgg accatgttct
     3961 cggagtggcc gcggtcaggc ggactcgaag agttcctgca cggactgcac ggacactgcc
     4021 ttgcgaagcc agcgcttgag ttgctcgagg tcggtgcagg cggcaatgcg ttggcgggac
     4081 tgctcatcca cctggaggcc ccgggctccg aggacctcca ggagggctgt cacttctccc
     4141 tcctgccgcc cctcctgccg cccctcctgc cgcccctcct gccggccttg ggcgaagtac
     4201 cgccgggcga actcgctctg gtactcgtag gtgccactgc tcatcagtgc ctccagggcg
     4261 gtgcgcgccg cgtcgttcag cgagcccatc accaggtcaa aatagaagcg cgcccgctct
     4321 tcatcaatcc ccaccaggcc gggcagcacc gcatcggcga tggccgcgcc cttctctccc
     4381 tgcccgtgtg ccatggcgga cagcaccgcc aactccaccg cctcacgcgc ctgctcgggc
     4441 cgcgtaatga ccggaatgcg ctccggtccc gccacgcagg gcctcagcac gaagcccggg
     4501 tggcccaggt ccaccggctg cccgccccag cgggccaccg gcccgtctgg agccaccacc
     4561 agcagcaccg tggggcacct caacttcgcc ctcatgtggg tgaggtacac cggccacgtg
     4621 taccgcttct cctcgtccgc agagagctgc acctccacca cgatggcgaa gcgcggcgtg
     4681 tcctcccaca gctgtaccac cagatccgcc cggtactcgg tgggtaccac ctgggtcagc
     4741 tccgcggact ccgcccgggc ctccgcgtag gcgggcacct cgacaccgag cgcgtcccgc
     4801 agcaactcgg ccgccagggc cgggcggttg cggaacaact ccaggaaggc ctcgtgccgg
     4861 agggaaggca tgcggcggcg aatgtgactc catgagtcac ctcgctgtca agcccagggt
     4921 tgactccaga agtagtgctc caactccccc agagcctact tgggcatcat cccgaaggcc
     4981 ttgagcatcg ccacggcgat acccatgagg ctctcaccgg cgatgaagcc ggagctcacc
     5041 gggagcaccg tggcctcggc cagcttcgcc ttcttgcggc gcagcacctc ggcgatggcc
     5101 gcgccgatga agaagctgat ggagctcgcc cccggaatca cgatggacag ccccagtccc
     5161 gacgccgagg ggatgaacgg cttggccttc ttcggcgccc agcgatccag cagcaccagc
     5221 gccacaccca gcgccaggcc gcacaccgcg ccgatgcgcg ccgacgtgtg cagcgagttc
     5281 accccgttga cgagcatctt cgacacgccc gcccacacca gcgaggacgg cgcggggaac
     5341 tcctcggtgc ccagcacgtc cgcgctcggc accagcaggt tgaaggcggg caccaccacc
     5401 gccgccccgg ccagcacgcc gaagagctgc ccgatgaact gcttgcgcgg gttggcgccc
     5461 agcagccagc ccgtcttgag gttcgtgagc aggtccgccg agtgcaggcc cacgccgccc
     5521 gtggcgttgg cgctcatcac gttggccgcg aggtttccgg gcaggagggc tccgtagagc
     5581 agctgcgtca ccggcccgag ggccttcgtc ggcgtggtgt ccgtctctcc cgtgacgcgc
     5641 gcggcgatga cgcccatcac caccgacagc ggcagggcga tgacacccgc ccaccacgga
     5701 atctggaaga ggtaggccat cagccccacc acgatggggc ccagcaccag gaagcccagg
     5761 gggaaccagg tgggcgggca ctccacgtcc gcgagcacat ccttctcctc ctcggtgttc
     5821 ttcccgaaga ggcccgagag cgccttgaac gacttggcca cgctgcgcca ctggaaggcg
     5881 aaggacagca ggcccgagga caccagcacc gaggcgcccg tccacagcgc ccagccattg
     5941 atggccttgt acgtcacctc ggggatgacg ccgcggctga ccatctccgg agcgaggaag
     6001 ccgtaggtga agatggcgcc cagcagcatg gaccagcccg tcttgaagct caccagcgcc
     6061 ccggcgccaa tcagcagcag gctcagatcg aacgagagcg tccacgcccc cgccggcttg
     6121 cccatgatgg tgaagggcag gctcagcttc gagggcaggt tccacgccag ccacgaggcc
     6181 ctgccctccc gccagaacgc gatgacggcg cccaccaggc ccgcgaggcc caggtagcgc
     6241 gccttgccgc gcgatccctc gtcatgcccg tgaagcgcct ggagcgtctc ggcggtggcg
     6301 gtgcccgtgg ggaacgggag ctgctccacg ttgacgagct ggcgtttgat ggggatggcc
     6361 gcgaagacac ccatggtgga aatcaccgcg aaccaggcca ccagccaccc cgccgacggc
     6421 agcgtcccgg tgagcatcag cagggcgggc acggccgcca tgttgccccc gcccgtcatg
     6481 taccccgctc ccgaggccac cgagcccacc gcgttgttct ccagcgccgt cacttccttc
     6541 ttcaccagcc ccacggcccg cagggcactg aaggccgcga aggagaggac acacgccgtg
     6601 atggtgacgc ccaggctcca gcccgtcttg aggatgacgt acaggttgga caggcacatc
     6661 accgcgccaa tcagcatgcc cgccacgacg gcacgcacgg tgagctggtg ctcggccccc
     6721 ttgtagacgt tctcgagcca gtagcgctcg ggatcctggg tgccggcgga gggcgccgcc
     6781 gggtgcgggg gctcgggcgt gagcttgagc tgctggggcg aaggcgtggc ggacgggctc
     6841 atggggggtg cacgataccg gaacaccccc taccccacga gtgggtattg ctcccgccgt
     6901 ccgctcagtg cgctccgccc ggcccgtggg cgtggccgtg ctccttctcc tcgtccgtgg
     6961 ccgcgcgcac ttcacgcacg gtgatgtcga aatggagcgt cttgcccgcc atcgggtggt
     7021 tgaggtccac caccaccttc tcccccttca gctcgcgaat cgtgatgggg atgacgtccc
     7081 cgtccgccgt ctgcgcgctg atggtcaggc ccggctggag ctgggcattg ggcgggaaca
     7141 tctcgcgggg cacttcctgg aggcctcgcg gatcatgctc gccgtacccc tgcgagggag
     7201 gcaccaccac cttcttggac tcgccggcgg ccatgccctc cagctggccc tccaggcccg
     7261 ggacgatctg cccccggcca tgcatgtagg cgagcggctg tccgggctca ctctcgtcga
     7321 ccacctgtcc gtccccgagg tgcaaccggt actccaacga gaccacactg tccttggaca
     7381 ccttcatcgt gggctgctcc ttctgtccta cgggtatggg acggagatgt agccggggca
     7441 agcaacccgt gctcccttga ttgctcagga ggcggacgac ctgggctcca gctcggcctc
     7501 ggtatccaca ttgggctcac cccgggacac gtagacggcg gccgcgaggt ctcccgtcac
     7561 gttgagcgtg gtgcggcaca tgtccaggaa gcggtccacg cccagcacca gcgcgagccc
     7621 ctcgggggga atcttgaaca tgcccagaat catcgcgatg acggggatgg agccggccgg
     7681 cacgcccgcg gtgccgatgc ccgccagcac gcagatgaac atcacgacgg cctgatccgg
     7741 caggctcagc tgcacgccga acacctgcgc caggaagagc acggtgacgc cctcgaagag
     7801 cgcggtgccg ttctggttca tcgccgagcc ggcggtgagc acgaagcgcg acacgttgcg
     7861 cggcagcttg aggttctcct cggccacctt gagcgcggtg ggcagcgtgg cgctggagga
     7921 cgccgtggag aaggcggtga cgatggccag gcggcagtcg cggaagaagg ccaccgggtt
     7981 gcgcccgccg aggaagcgca ccgacagcga gtacacgacg aacatgtgca gcccgagcgc
     8041 cagcagcacc acgcccacgt aggacgccac ctgcatcagc acgcccatgc ccaggcgcgc
     8101 catcatgctg aagagcagtg ccgccacgcc gatgggcgcc agcttcagca ccccatcgat
     8161 gagcttcatc atcacgtcgt gcaggccctg gatcgtctcg cgcaggtgcc tggccgccgg
     8221 ggtgtccgtc agcgccagcc ccaggccgaa gatgagcgag aagacgatga gggcgatcat
     8281 gtccccgtcc gccgccgcct tcagcgggtt gctgggcacc atggcggcga tcagcgaggg
     8341 caccgaggtg ctgctcggcg cgggggccgc ctgcaccgag gtgcccttca tcgccagcgc
     8401 gcgcgcctcg tcactcagcc ccacgcccgg tttgagcgtg ttcaccagca ccaggccgat
     8461 gagcaccgcg atgctggaga tgaccacggt gtagcccatg gtcttcaggc ccagccggcc
     8521 cagctgcttg aggtccagct cgcacacgcc catcacgagg gcggagaaga gcagcggcac
     8581 caccagcatc agcagcagcc ggaggaagag ctgccccgcc agcccggtga tgttcgccac
     8641 cacccactcg agccagggcg tccctcccgc cgcgaggttg gcggcgatgc ccgccacggt
     8701 gccgatgacg atgcccagga gcatcttctg gtgctgcttc atccgggtgc ctcttgggtg
     8761 ctggggagaa gactccctgg ggacagggag ggggcgcagc ctaccggcga ttccccgtgg
     8821 cggatacatc atcggcggtg gcggccgtct cccgctggac tcccgcgccc ctggcccgtt
     8881 cacccgccgt ctcacgcagc cgccggttca cccgctcggc ccactcgggc tccacctcca
     8941 ggcacgccgc cctgcgcccc aaccgcagcg ccgccgccgg catggagcca ctgcccgcga
     9001 acgggtccaa cacccagtcc cccggccggc tccacgtacg caccaacggc tccagcacgg
     9061 agaagggctt gtggtgggga tggttgcccc aacgggccgc ctccgcgtcg tcgtcgtagc
     9121 cgcccaccac cgcccagacg gtgggcaggc cacccggctc cagctccggc gcgggcgtgc
     9181 gcgagagcac cagcgccacc tcgtagacgc gcagcagctg ctcgttggcg ttcttctccg
     9241 tggtgcgctt gccccagacg tactcgcccc gcaggtggtg gaagcccaac gagcgggcca
     9301 ccgcgagaat gggctccttg cccagcaggt tcgtccagat ggccatcggc gcgtccggcg
     9361 tcaggtgcgc caccgcgtgc gtcatccact cctcggtgaa gacgcggtag tcgcgcaccg
     9421 tctcgaagcg cacgatgggg ttgcgatcga tcttcttgtt cgcccgggga tcccgcaggt
     9481 ctcccccctt gcgccgccgc gtgagcaggc aatacggcgg atccgtatgc aggaaggtgg
     9541 ccttcgcctc tcccagcacg gcccggtaac cgccgggctc ccgcgaatcg gcccgcacgc
     9601 agcggaaggt ctcgagctcg tcgtgaggat tcatccggcg cgcaccctac cccagccgct
     9661 ccgcttcacc accgcgcctc gggagccacc gcccgcgtca cggccaggat gtctcccacc
     9721 ggcacccgct cgtgcgaccg gaagacggcg aagtcgtccc cccgctcggt caccacgtcc
     9781 agcacctcgt cgatgaaggc ctccccctcg cgcagctgga ccgccaccgg ccggtgccgc
     9841 aggacggcct cctccagcac gtcgatgaag tcacagcggc ccacctcgtc ctggcatatc
     9901 cgcgtcatcg tctcgccgcc tccggcgcca aacgtaatgg ctccccccgg gccccgccca
     9961 ccggaatgaa ccggccggcc cccggaagtg cccctcccgc tcaccgcttg cgccggcccc
    10021 gtttgggcgc tccgagccgc tgggcctcct ccacccagtg gcccctcagg cgcgcctccg
    10081 tggcgagcgc ctcgtcccac gagggcccgt ctggcagcac gcgcgaggcg tgctcgagca
    10141 tgagccgctc cagcgcccgg tcctcgcaca gccgccacac ctcgtgcgcg tccaggccac
    10201 aggcggcgag gtacgcgtcg cgctccttcg gcggcacgcc cagcagctcc caccactcgt
    10261 cctcggcccg tatcacctcc tcctcggtgg caagcaggcc gagcgaccgc gcctggcccg
    10321 cgagcaacgc ccgccgcagg cccgcctccg ccagctcccg ggcctcgggc gcggcgcgca
    10381 gcccgcccag cacctcctcc gaggacacga ggcctccttc cgtctcacac agaccctcca
    10441 tgaggcggcg gcggcgcacg taggacgagg gaggcggccg gcccgtccgg gctcgcacgg
    10501 gggcctccgc tcccgaggcg atccacgccg aggcggcctg gaggcaggca cgggcgtcct
    10561 cgcgcttgag atcctcgaag cctccggcgg cccacgcgtc ccacttcgcc cgggtggccg
    10621 gacgccacgc ctcgcccacg gccgccagca cccggggcca ggtgcggtcc tggtagaaga
    10681 gcgccgccgc cgcgtccacc agcgcctgcg cctcgcgggg agcgagcacc ttcgccccct
    10741 gcgcctggcg cgccgcgtga cgcacgttga cgagcggcac cgtcagggca cggaagccgt
    10801 gctccgcgtc ggcgtggagc agcgccacct cggcgtcatc caccagctct ccccgctggt
    10861 aggcctcgaa gatgtggccc acgcccacca tgccgtgccg cgcgagctcc gccgcacgca
    10921 gcgcccccat gctggccccg ccgaacaccg ccaccccggc gtccagcgcg gccagcagct
    10981 cgtggtgcca gacggacggc tgcgcctcga agaccccatc caccagggcg atggccctcg
    11041 gatgcagcga gagggcgcgc cacacgtctc cctggcgcgc gggcggcaac acccggcagg
    11101 gcaccagggc cagggcgtcc tcctccggca gcgaggggcc gaggaagacg aggagatcat
    11161 cgggatgatg ggccggacgt cgtttcacag cagctccgac acacgcagac ccggcaccac
    11221 cacgcgcacc acgtggagtc cggggagagg ggtctccagc tcgacggcgg cggcccggcg
    11281 gaagcccgcc ttcccgagcc gtgccagcac ttcgcgcacc gcctcctccg gcgaggacac
    11341 ctcaccggag acatcgggca tggacgtcac ggcccgccgc ggacgcacct ccgcacaggc
    11401 ggccgccagg gccagcgtgg cctcccggtc tcccgcggcc acgtcctcgc gtgcgccgtg
    11461 gatgtcggtc agccgggact gggccgcctc cagcagggcg ccgagcaggg cctggtccct
    11521 ccccagcccg caggcgtacc cggccgccag gggcaccggg ccctcctcgc ggtccacgag
    11581 cagcgcggcc cccacgggca ggcccgcggc acggggcgtc cgcgcgccgg gcgtgagatc
    11641 gaagaggtag acggcgaagc cccgctcgcc cagggcccgc gcgagcgccg ccgtccgggg
    11701 agcgccctgc tcgaggtctc ccgggcgcaa caggcgcgag aggaggacct cctcggacca
    11761 cccttccggg aggatgcgcg cgagctggtc ccgctccgtg gcctccagca gtgcgtgcag
    11821 gagcgcccgc gcccgctcgg ggtgcgcgcc cgagccgttg ctcgtccact gcacgctcac
    11881 cgggccgagc gccggagccc cggtgggcgg gcagtacacc ccctgggccg ggaggagcac
    11941 gggctgcccg gactgcagct cggtggcctc gcaccacgcg taacgcatct cgcggctcca
    12001 caaccgggag atgaccacgc cgccccgggt gcccagctcc tcggcgcccc agacggcgcg
    12061 gccccgagtc tccagcccat ccatggagcc ccagacgagc cgctccatgg ggacgcgctc
    12121 ggccccccac agctccgccg tctccaggag cgctccggcc gacgccgcct ggaaatccag
    12181 gcccttgccg ttgcacacct ggagcacgta gccgcctgga cgcaccgcgg cagccacctc
    12241 caccccggcc cggtccaacc ccgtcacccg cgccacccgg gtgacgccga gtccatgagc
    12301 gagacggtcg agaaaggagg aggtcaacgg aacagcggtc gggagggcca cgggggagct
    12361 ctgtgttggg tgagcgagga cgtctcggcg ggaagcatgc taggggagtc cggcgtcagg
    12421 aggccgaaaa gaagatgctc gacgtgggac aagccgcccc ggacttcacc ggcaccgact
    12481 gctggggacg caccttctcg ctctccgcgc tcaggggaag gcgggtggtg ctcttcttct
    12541 tccccaaggc cttcaccctc gcctgcacgg aggagacgcg ccacttccgg gacaaccacg
    12601 agcggattca agcactcggg gcggagctgg tgggcgtgtc ggtggacacg gtgaagacgc
    12661 agtgcgagtt cgccgagaag gaggacatcc acttctccct gctgggcgac gagggacgca
    12721 ccatcagcca ggcgtatgac gtgctgtggc ccgtgctgaa ggtggaccgg cgcgtcacct
    12781 acatcatcgg cccggacggc cgcgtcgagt ccgtcatccg ccacgaggtg cgcgtctaca
    12841 agcacctgga cgacgtgctg cgctacctga gcgagcaccc gctaccgtcc gcgggcgcct
    12901 agagctccca ggcgcagtcg tactcgcagt ggccgttgcc ccgggcacgg cacttcttct
    12961 gctcgatgcg cacgccccgg ccaccgctca tctcgatggc gcgctcgtac cagccgacga
    13021 tggtgaggca gtcggcctcg gtgacactct cggcgcccac ggtgcgcacc accgcgctgc
    13081 ggggtccggt cttctcgtag gtgcgcgagc ccaccgcgta gtagagccgg tagatctccg
    13141 gcgagtggct gaggaggaag tgcggatccc ccttgcggat gaacacgtgg tgggggccgt
    13201 tcagattctc ctcggcggag gcgcggccca tctcgacgaa ggccttgttg cgatccctgg
    13261 gcgagagcgc atcggcgatg gccgcgtcga ggcgggagtt gagctccagg gggtaccagc
    13321 cgatgggcat gatgacgctc tcgagcacct tgcgatcggc cggaggcaag cgctggagca
    13381 cctgttggag acgcccggtc ccgccctgct tcatcaacag attgaggcgc gtgatgagca
    13441 cactgccctt gatgcgtgcg gccgcgctgt ccattgccat gatgcgaatc ccccggtgag
    13501 ccccgccatt gtgtcagcgg gaggatgtgg gcggcaacct gcctggaggg gacctcccgg
    13561 gtggagcagg caggcgagcc cggtggcatg aacgccgtca gtgaggctgg agctcgcgca
    13621 gacgtttctc gagatcctcg ccgagctccg tcggccggcg cagcaccgcg gccatcatga
    13681 ccaccgtggt cgccgtgagc tcgtctcggg catgcagccg gctgaacccc tcttgcatgt
    13741 ccgcgagcat ctgccggaag tccacgcgta tctgacggaa ctcctcgcgc atggactgga
    13801 actcccctcg catgtgatgg aactccctgt tcattccatc acgccaggtg cggaactcgg
    13861 cccactggcg ctccgactcg gcccgctggc gctccaactc ggcccgctgg cgctccaact
    13921 cggcccgctg gcgctccaac tcggccccca ggcgctccgt cagcttctcc tgtcgcacca
    13981 tccgggagtc caggcccgcc acctgcgtcc tcaggtccgc cacctgggtt tccagcctgt
    14041 cgatccggac ccccagaccc tgaacggcat tcaggatctg cgtgccaatg tcagtcccca
    14101 tcatctccgc catgttcaca ctcctcgccc gcccgggcag tccgtgagcc cgtcagccca
    14161 cgccgcacag aataacggaa caccctcacg atgcgaacct ttttctaacc tttcaagtag
    14221 ggtcccctcc cctacttccc agaaccccac cggggacctg ggggcccacc ggaaaatccc
    14281 ctttaacttt tcgccggctc cggtgttcgt aggaggcgtg aaggccctgg agacatccct
    14341 ggcgttggcg gaggccgcca ccgagccgag cgacgaggcg ctctgccgtg ccttcctggc
    14401 cggtgacgag gcggccttcg gcacgctggt ggagcggcac cgggccctgg tcttctccct
    14461 cctgcgccgc tccacgcgcc ggcccgagga cgcggcggac ctcgcccagc aggccttcct
    14521 gcgggccctg gaggcctcgc gccgcgtctt cgcccgctgg agcccctcgg gccccgcccc
    14581 cttccgggcc tggctcatcc gcatcgcgct caacctggcg aagaaccatg cccgccaggg
    14641 ccggcgctgg ctccaggccg tgcacctccc ggagaccgag tccccggaag agtccgcgca
    14701 cgagtcgctg gagcggaccg aacgggagcg gcaggtgcgc gcggcggtgc tcaccctgcc
    14761 ccgccgccag cgcgaggtgc tgaccttgcg agtcgacggg gggctgggct tccgggacat
    14821 cgccgagacg ctcggcatca ccgagacgaa cgcgaaggtg aatttccatc acgccgtgaa
    14881 gcgcctccgg gcgcaggtgg cggagccgtc cgaggaggag cgctgatggc ggcatgccag
    14941 gacaacgaag aactgctgac cctcttcgcc gcgggagcgc tggagcccga ggaggaggca
    15001 cgggtgcgcg cgcacctgga cacctgtgcc acatgccgcg cggaggcgga ggcgaaccag
    15061 gaggtgctcg gcctggccgc gctgccgccg ccctccgtga aggaacaggc catggtggcg
    15121 gcgctgcccc ggacgacggt gggcgcctgg cgcagggccc aggtccagca ggcggcgcgg
    15181 atgaggaccg cgggagcgct gatggcggcg gcggccgtgg tgttgctggt gctgggaccg
    15241 gtgctgcagc gccgggtggc cacgcctccc acgcccaccc ctccggtgga agcgcccgcc
    15301 aacacgcccg aggaggacgc cgtcgcgctg gagcagtggg cgctggcgga tccgctggcc
    15361 gacgcgctcg acctgtccga ggcggatctg gaggagcccg agtccgacga gctcctggac
    15421 tccgagctgg atgatttctt ctcagacacg aaccctggag aatcgctgtg atgaagccct
    15481 ttcgattggc ggtgctgacg ctgtgcctgc ttcccctggc gtccctggcc cagacgcccg
    15541 aggcgaagga agccgcggag cgggcggagc ggcagacgcg cttgatgcgg gtggtggggc
    15601 tggccgagga gctgggtctg gaggaggccc aggcgctgaa gatggcggac acgatgcgcc
    15661 agttcgacga gcgccggcgg cccctggtgg agcaggtgca ggagtccgcg caggtgctaa
    15721 ggaaggcggc ccagggagac gcctcgacgc agtcgcaggt ggaccaggcg gtgcagcggg
    15781 tgttcgacgc gcggacgcag ctcacggcgc tcgaccgtga catgtaccag gcactcgcca
    15841 gggacctgcc tccgcagaag cgggctcagc tcgccatctt catggcccgg cacgacggga
    15901 agatgaagat ggagaagatg ctgaggaagg ccgatcggga gggccggcgc gaggagcggg
    15961 agaagcgcag gcaggagcgc atgcagcgga tgcagcagcg catgcaggag cgcgaccggt
    16021 agcgcccgcc ctacacgcgc accagcaggg ccacctggtg cgcgccgatg ccgatgccga
    16081 agagcacgag gtacttcgtg cgcagctcgc ggtggtggcg ggccagggtg acggggatgg
    16141 aggcaatcac catgttgccg cagtcctcga gggtgtgcag gtactcgcgc gggcggatct
    16201 tctcgttcca gtggtccagc agcttgcgcg tggcctggtg tgacacgagg gtgatgtcat
    16261 ccccggtgag cccgtgcttg cgcagcagcc gctcgacgag cctcggcggc ccttccatgc
    16321 cggtattcag gaaggcctgc acgccccggg agggctcgag tccgtacacg ggggtggtga
    16381 agccggcctc ggggcgggag cgcatcgtca tggccccgta ctcgtcgctg aaggtgtccg
    16441 cggcgtagtc caccaggacg agccgctccc cggcacccag cacggccgcg cccgctccgt
    16501 caccgatgcc gaaggcgtgg ccctgcgcgt agtccacgtt gcgcgtccac cccgccccca
    16561 ccgccacgag cgcccgctcc gagtgccccg ccagcatcgc ctcccaggcc agcaccgtcc
    16621 ccatgacgaa gttgccgaaa tccgcctgca ccggcaccac caacgcgtgc gagcccaggc
    16681 ccagctcccg gtgcacctgg tacagcgcgt tgggcgagac gaactcggac acggagacgt
    16741 agccgtagag ccggtccacc tgctccggcc gcacgcccgc gtcctccagc gccgcgcgcc
    16801 ccgccttcgc cgtgagcgag gccagtgact cgtccggcgc caggcaccgg tgctcccggt
    16861 tgccgtagaa gagcgaggcc tcggacaacc cctgcgcgcg ggcggcctcg cggatgcggt
    16921 cgaagatggg atcggcgctg gtgcggaccc gctccggcag cgcggagccc aggcccagga
    16981 aggcaatcga aggacgcgtc atcgcaccgg actagagcac accccgccct ccagacgggg
    17041 cctctcctgc ccgtccgtgg agcggccgag cacacagcgc tgcaccgccg cctcctggcc
    17101 gctatggaga gcacctcatg agcgcactct ccctgagata cgtggccctg ggtgactcct
    17161 ccgccgtcgg agtgggctcg cgcagtggtg gctacgtcga acacctcttc caacggctgc
    17221 gccgcacccg cccgggtgtg ggcctgctca acctgggcgt cagcggcgcc accagcgcca
    17281 ccgtcctctc cggacagctc cccaaggcct cccgctcccg cccccatgtg gtgagcctcg
    17341 cggtgggcat caacgacctg tggcgcggcg tggagcccca ccagttcgag tccaacctcg
    17401 atcagctcgc gcgcggcctc gtggccaccg gcgccccggt ggtgctgtcc aacctgccgg
    17461 acatgtcgct cgcccccatc gcgcggctgg cgacgcactt cctgcccatc cagctcatct
    17521 ccgcgcggat cgcctccttc aatgaggccg tggcccgtgt ggtggcccgg catggcctgc
    17581 tcggggtgga tctccacggc cccagcctcc aggagctgcc cggcagcacc gactacttct
    17641 cggccgatgg cttccacccc tcggacaccg gctaccagcg gatggccgag cacttctggc
    17701 ccgtcctgct ccaggccgcc gagctcggcg ccagcaccga gcgggccacg ggctgaggga
    17761 aggcctcgag gggcttcaag ccgtcgcgtg gaggtaggtg tcgatggccc ggttcaccgc
    17821 ctcgggagcg ctcaggtggg gcaggtgccc acgcgcggcg atggtcatca tcctcgccag
    17881 tggaatgcgc ctggccatgt actcgcctac cgggttgggc acggcgaggt cctccccgga
    17941 gtggatgatg agcgtgggca ccttcaaccg cggcaggtcg agccgatggt cgtactggaa
    18001 gatcgtccgg gcgagggcca gcgcgatgtc cggccgcatg gaggacagcg tgcgggcgaa
    18061 ctcctggccc agctcgggcc gctcggggtt gcccatggcc aggggcgcga agccgctcgc
    18121 ccacgtgtgg tagctggagg ccatggcgtc gaagaacgcg tcgagctccg cccggctgaa
    18181 gcctcccacg tagcccgact ccggatcatc caggagccgg ggcgtcgact tgacgaagac
    18241 gagctggcgg aagcgccggg gctccaccat ggccgccagc acgcccacca ttccactgaa
    18301 ggagtggccc acgaagatgg tgtcggagag cttcagctcc tcgcacagct ccagcagatc
    18361 ctcggcgtag gcgtgaacgc cgctgtagcg ctgcgggctg taggcgttga agtcggaccc
    18421 gccgcacccc acatgatcga agaggatgat gcggtagcga tcctggaagg ccttcacctg
    18481 gtgccgccag gcgctctgct cggagccgaa gccgtgggcg aagatgagcg tgtcccggcc
    18541 actgccgagc acctgcacgt tgttgcgttt ccggatggcc tggcccatga cgctcacact
    18601 cccatcgagt tggtgagcgt caatcctgac agcacaccgc gttcgccgac ctgtcctcaa
    18661 tcccggtgga aacgcggatt gcagggtaga acacctccgt ccggggtgta tccgtccaac
    18721 agtcaacacc tacccggcag ggctatggcc cggtgcccag cgcgcgcacc aggaagtcgt
    18781 cgaaccagac gcccgcgatg ggcgtggcga gcccggcgta cccctcgccc gtgagcgcgg
    18841 ccgggtcgtc gtccgtcacc ctgagacgga cctgcccctc caccgaggcc gagagccgca
    18901 ccgggcccgc gccccagacg gacagggaga gcgtcgcggc ctcccaggga gccgccagtc
    18961 cactggccgt ctcgccgagc acgatgaagc caccgccccc gtaacggcgc agttggaggc
    19021 gcccctgcgg caacagcacg agcgcatagc gtgcatcggc ctcggcgcgc accacaaggc
    19081 cggcctcgtc cgcgccaaag gcctgcagcc gcgcctgcac ctgacagtcg tcacagcgcg
    19141 agggcagcgc gaaggcgagg ttgtccccat tcgggttgtc gaggtcactc accgcacgcc
    19201 gcccatccgt cagccacagc ccgctcagct tccagtcact cccgaggctg ctcgacgagg
    19261 tgcgcggaaa ggtgtcaccg aagaggagct caccgggctg cggctcggac ccgggcgcat
    19321 cctcgtcctc gtccgggggt gcatcgtccc cgcctccacc gcccggcacc gcgagggaca
    19381 cgcgggacac gtagccacgc gagttggcgt cgggggcgtc cccgaagaag cagggcacct
    19441 cggaggtacc ctccggcaac gtctccaggg cgttggggta gcccttgtag gtccgccgcg
    19501 agtcgagcac caccggctcg ctgaagcgcc catccttcag cacccgggca cgcacctcgt
    19561 agctcacgtt gggctcgcgc atggtgttgt agaagacgta cagcgtgtcg ccgatgcgcg
    19621 tggtggccgc ctgcatcgcc cagtcccgcg agccctccag caacgtgcgg gggccgaacg
    19681 tgcttccatt gaagtggcgg tggtagagac gctcggactc gtccttgtag acgaggtgca
    19741 tgcctccccg gccgtccgcg acggcgctca acgcggcccc gtggtagatg ccctcggaga
    19801 aggcgtcgcg cacggcgctc caggtgtcca gcggatccgc gtcatctcgg aggcgcaggc
    19861 gcgtgggctc gaaaccatcg tgcatggcgt agacgaagac gagcttcgag ccgaggctca
    19921 gcaaccgccc gccgccccgg cgcttcaccc ggcccaggtt cgcctgccgc tggaagctcg
    19981 cgcccccatc cgtggagacg gacagcaccg cggtggagcc cccatccgag tccaggcgga
    20041 aggcctgcac ccacagccgg ccccgcgagt cgcgcgcgag cagcgcccgg gagtaggccg
    20101 tggtgtcatc ggcgtcgaag acgcgcaccg ccggctgggg ggcccagtca tgcgtctcgg
    20161 gccggtagcg ccaccactgg aagtacacgt cgtgtctgcg cgaggccgtc agcctgggcg
    20221 cctcgaacga gtagacgagg gccacgtccc ggcccaccgc gagcacctcg gcccggtccg
    20281 cgtggctggc gtccggttgg atcgccgcgg cgaagcggaa cgtgcgccct ccatcgtccg
    20341 agcggaagaa cgacaacccc cggccctccg cgccttcctg ctgcacggtg agcaaccagg
    20401 tgggcggccg cccacttccc gtgtcgatgc gcaccgcgtg tcgttgagcc ggcaaggtga
    20461 gcgcgtttcc accgctcacc ggaaccatgg gcgcaaggct cgcgagcacc gtcgcgagca
    20521 gcgccgtcga aaaacccacc atccgtcccc ctcccccgta atccccgaga caaactaagg
    20581 cgctcgggga cgagaggaaa gcgccgggcc tccaccggac ctggaccccg gtctcagtcg
    20641 aagagtggca ttccggtcat tgccttgccg atgaagtcgt agagcagatc cgtggtcggg
    20701 gacatcacgg tgacggcgcg ggcgtcgcgg aagtgccgct cgatgcccac ttccttgcgg
    20761 tacgccgcgc caccacacac gcgcatgccc agctcggtga cctcgggggc cagctcgccc
    20821 acggcggcct tcacctcgag cacccgcatc tgcgcgtcct cgcgcttcga ctcgagggca
    20881 tccagcgtgt cgcggatcag cccgcgcacc aggtccgtct tcatgcgcat gcgcgccagg
    20941 taggcccgga tggtggccag gtcggccagg gactgcccgg tgtggagcag ccgcgtcttc
    21001 gtcacgtgcg ccgccgcctt gcgcgtggcg gcctccatga tgcccaggta gcaggcggag
    21061 cccagcacct ggaagtgggg cagcacgttg cccatcatga tgtcgaaccc gcctccgtcc
    21121 ttgccgagca tcgccgagcg gggcacccgc acgtcccggg ccacgatggg gctggaggag
    21181 ttgccccgca ggcccattcc atcgaacgcc acggggaacg acagcccgtg ggcgttgccc
    21241 aggaccagcc agagcgtgct catgcccttg gcctccaccg gcttgctcga ccagacgtag
    21301 ctgtcggcct ggccggcgga ggtggcccag ctcttctccg cgtccagccg gacggtgccc
    21361 tcctccggca cggcgagggc ggtgctcact ggcgcccaga agtgactgcg cgagcccgcc
    21421 tccgacaggg ccagcgtcgt cacgtggcgc cccgccgcga tggcctcgcg gatgtctcgc
    21481 ggcccgtgct gctcgatgac cgccgcgccg cagaagtgca tgcacagcac catgccgctg
    21541 gagccacacg ccgtccccac ctgctccacc atcgtggccg ccgcccggag cccctcgccc
    21601 cttccgccca cgtccctcgc gctgagcagc cccagcaggc ccgccttgcc cagcgcctcc
    21661 atcgccgccc ggggatagac gccgtaccgg tcgacctcca tggccttggg ctcgatgact
    21721 tcggtgatga tgctctcgac ggagtgcatg ggtccggctc ctcggagatg aaggggcgca
    21781 gagggtagca acccgcgggc cggaatgggc aagggacaat ctggtaagag gccgccccat
    21841 gacttcgctc gagctgacga ccgacgattt ccggcgcctg gcccaccgtg tctccaccct
    21901 cgccgagcag tggctcacgg agctggatgc acgcgccatc gctcccgccc tcaaggggag
    21961 tgacaccgag gccctcttcg ccgagggatt gcccgaggag ggcctgaagg acgcggcgct
    22021 ggacgcactg ggcacggtga tcgccgggac acgtgcgggc aacgcgcgct ttctcgggta
    22081 cgtgctcggc tcgggcgagc cggtgggggc gctcggggac tacctcgcga gcgtgctgaa
    22141 ccagaacgtc accgcgtggc gctcgtcccc cacgatggtg agcatggagc gcgcggtggt
    22201 gcggggactg gcggcggcgg tgggctgccc cggcttcacc gggagcctca cgggtggagg
    22261 ctcctcggcc aacctcatgg gtttgacgat ggcgcgcgag gcgaaggctc cggccaacga
    22321 ggagggctcg ccctcggggg tggtgtacgc c
//
