LOCUS       NZ_CP011509            20633 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Archangium gephyra strain DSM 2261 chromosome, complete genome.
ACCESSION   NZ_CP011509
VERSION     NZ_CP011509.1
KEYWORDS    RefSeq.
SOURCE      Archangium gephyra
  ORGANISM  Archangium gephyra
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Archangium.
REFERENCE   1  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Genome assembly of Archangium gephyra DSM 2261
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) Protein Science and Engineering, Institute
            of Microbial Technology, Sec-39 A, Chandigarh, Chandigarh 160036,
            India
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: HGAP Pipeline v. SMRT v2.3.0
            Coverage                          :: 79.3
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001027285.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:37:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,001
            CDSs (total)                      :: 9,898
            Genes (coding)                    :: 9,822
            CDSs (with protein)               :: 9,822
            Genes (RNA)                       :: 103
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 28 of 76
            Pseudo Genes (incomplete)         :: 45 of 76
            Pseudo Genes (internal stop)      :: 6 of 76
            Pseudo Genes (multiple problems)  :: 3 of 76
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9122030
            Orig. end                         :: 9142663
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20633
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="40"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20633
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20633
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10633](+)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10633
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     gene            complement(1281..1826)
                     /locus_tag="AA314_RS35470"
     CDS             complement(1281..1826)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS35470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_047859127.1"
                     /transl_table=11
                     /translation="MTSSLKLWIPFTLVTGWALGHGTSLVMSSPARASESSAQAFEDLS
                     ARIESLSAQLSTLQSQVRCQGGTTAAALDVASSNAEFRRILREELTTSMVNSESSKATP
                     PAIVHEGVSPTSLAAQERGQRLIEDALRAGRWGDAQVATLRGLFAEMTATQQQKLAQKL
                     AASINRGELVVETTDMPF"
     gene            complement(1917..2324)
                     /locus_tag="AA314_RS55365"
     CDS             complement(1917..2324)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS55365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_147332765.1"
                     /transl_table=11
                     /translation="MSRYTRIPALVALMAAMNLSTAAWAGAKGGSGVSIVFSGDNGTAS
                     GTMGTVRGSSDTLQYIGCTVSATAGSSRAVWCSARNSSNVTVTCSSAEPEIVQVMDAVT
                     SDAHIAFSWDAQGSCIGLSVRPDSRYKPKEV"
     gene            complement(2622..2957)
                     /locus_tag="AA314_RS35475"
                     /old_locus_tag="AA314_07262"
     CDS             complement(2622..2957)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS35475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_07262"
                     /product="hypothetical protein"
                     /protein_id="WP_047859128.1"
                     /transl_table=11
                     /translation="MTTGIRLTNVSAENAALPRLQDAILGPETLEQLFRDIQRCAVVDE
                     VLLKGSAALMASEKSVPLPEAELALREKRVAGVQIRYWYEGANWWDTLMHTPRGVRLIR
                     IEHRLGG"
     gene            complement(2954..3436)
                     /locus_tag="AA314_RS51205"
                     /old_locus_tag="AA314_07263"
     CDS             complement(2954..3436)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024634.4"
                     /locus_tag="AA314_RS51205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07263"
                     /product="4Fe-4S binding protein"
                     /protein_id="WP_053066955.1"
                     /transl_table=11
                     /translation="MSSQSTLSRRAFLGLRRHEAQPRPPAAPAPVSAPATPEPGFSLEA
                     FYSSRARSGEVTGRELPVFSLREGLAVPQESTRRMGVPVAGMTVRVRPQLCLAWQGSFC
                     GTCSERCPVEGAIAIESGRPSVVESRCNGCGLCVQACPAPLNALEFLPPRQQAPGP"
     gene            complement(3433..4221)
                     /locus_tag="AA314_RS51210"
                     /old_locus_tag="AA314_07264"
     CDS             complement(3433..4221)
                     /EC_number="1.9.6.1"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015828.4"
                     /locus_tag="AA314_RS51210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07264"
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="WP_053066956.1"
                     /transl_table=11
                     /translation="MSPEGGQGSGLGARWLQVGAAVAVALAATGYFAGLRAPEMPERPV
                     ASDPHAQRAERAPSYSELREQRRGANARMYEGAIDALAEEPFPVKPLPVATAEQRARAV
                     AQRQDHRAYDGAPPTIPHEIDQREVPGCLACHGEGMKLGNRVAPKISHPPYQSCTQCHV
                     VGESPRPLAQYKEGPGNRFVGLASAGKGERAWPGAPPTMPHPTLMRDDCASCHGPRGLL
                     GLRTSHPERQNCQQCHGSSARLDQRVNGAGGPGLALEARP"
     gene            complement(4218..6638)
                     /locus_tag="AA314_RS35490"
                     /old_locus_tag="AA314_07265"
     CDS             complement(4218..6638)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012602.4"
                     /locus_tag="AA314_RS35490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07265"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_116119861.1"
                     /transl_table=11
                     /translation="MDRRDFLKGTAMTAATLAASRLAYGQDKAAGTPPAAAPAGQGVQW
                     NKAPCRFCGTGCHVQVGVQNGKVVAIAGDQQAPVNKGLLCVKGYHVGLALYGSDRLTTP
                     LLKKGDTHVPISWEEAIDIVARRVLKDPKGFGLYGSGQWTIPEGYAASKFVKGGLGSNQ
                     LDANARLCMASAVTGFLATYGVDEPAGCYDDLDACDVLIMWGNNPAEMHPVLFSRVIDR
                     RSRGEKVTLIDIGTRKTRTSGFCDHSLRFKPNTDLAIACGIAHLLVENGTYDKAFVEAN
                     CAFRAPSEPAALEGKAITFEEYRELLEPYTPEKVEELSGVPAKDLRMLADLFGRRDVRI
                     TSLWCMGMNQHTRGTAINNLVHGLHLLSGHFGKPGDAPTSLTGQPSACGTVREVGTLAH
                     ALPGGRVVAKAEHRAQMEEIWNVPKGRLHDKPGYHTLEMWKRFSTPTEQGGDIHTIWVQ
                     VTNPAQTLPNTHKLVDPSRKLADKFLIVSDVYPSATARIADLILPSAMWVEKNGMVGNS
                     ERRTQQWFKMVKPPGQARDDAWQLIAVAHRLLELGFEGMKDKDGRFLFEVKGKDGKPVP
                     LWDFAHYYDVNVDEHLFEEYRKTTRIKHKDLAPYQEYVKARGLRWPVVQQPDGSWRETR
                     FRFAGFDDPYVKKGRDIQFYHSTTHDDRAQIWFSPYEPPPESPDAEFPFWLCTGRVIEH
                     WHSGTMTMRIPQLQRAMPQAYVEMNRADARRLGVGNGDQVTVETRRGKLDLPVWIGGRG
                     EPPEGSLFVPFFDERLLINWLTLDEHDPFSKQPDYKKCAARVRRRELVAEKQG"
     gene            complement(6641..6886)
                     /locus_tag="AA314_RS35495"
                     /old_locus_tag="AA314_07266"
     CDS             complement(6641..6886)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS35495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_07266"
                     /product="hypothetical protein"
                     /protein_id="WP_047859129.1"
                     /transl_table=11
                     /translation="MPISSLVLTLDASPELRASVLREVARDPRITLGPPLEERWLPVVT
                     ETGSLPEGEALAESLRDLPGVSFVDVVMVDFSEEER"
     gene            7124..7720
                     /locus_tag="AA314_RS35500"
                     /old_locus_tag="AA314_07267"
     CDS             7124..7720
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS35500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_07267"
                     /product="hypothetical protein"
                     /protein_id="WP_053066957.1"
                     /transl_table=11
                     /translation="MRPALAAVLLAFGGCGKDQPARFQPPPGAPTGKETLHQPAKLTSV
                     ESGQTDALGRPLRVSCESCHSLRETKPMPSRPEELKEFHQGLQFRHGELACTSCHQANQ
                     PRTLHLATGEPLPMPEAVTLCAQCHGPQYRDFKAGAHGGMTGYWDLSRGDRTRNHCVSC
                     HDPHSPKYAGGHPVMPPRHPSTQGEPDNKEARGHE"
     gene            7713..8618
                     /locus_tag="AA314_RS35505"
                     /old_locus_tag="AA314_07268"
     CDS             7713..8618
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024644.4"
                     /locus_tag="AA314_RS35505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07268"
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="WP_047859130.1"
                     /transl_table=11
                     /translation="MSDILSRRTVMKGAGATLGAAAFAHAMAPLTEWTQDLSVDEFLQK
                     HYKELTRDEMARILVHLKAEAKKTYGRDVDIQDLPPQEGVSFGYALNLSVCIGCRRCAE
                     ACHQENNHDRSTGNSYIRVLEMQQGSLDLEHGNANYDHPVPAEGKYYLPVQCHQCDNAP
                     CVKVCPVQATWKESDGIVVVDYNWCIGCRYCEAACPYHARRFNWTKPEIPPEELNPDQG
                     YLSNRVRPQGVVEKCTFCLHRTRAGRLPACLEACPTGARVFGNLLDPKSPIRWVLENKR
                     VFVLKEELGTRPRFFYFFDK"
     gene            8622..9890
                     /gene="dsrP"
                     /locus_tag="AA314_RS35510"
                     /old_locus_tag="AA314_07269"
     CDS             8622..9890
                     /GO_process="GO:0019420 - dissimilatory sulfate reduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dsrP"
                     /inference="COORDINATES: protein motif:HMM:NF045798.1"
                     /locus_tag="AA314_RS35510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07269"
                     /product="sulfate reduction electron transfer complex
                     DsrMKJOP subunit DsrP"
                     /protein_id="WP_047859131.1"
                     /transl_table=11
                     /translation="MAATRHLLDYPRFLGRLLWMSTDGSWRFYTWMTVLTAIALVGANA
                     WAHQLAGGMALTGMSDHVSWGLYIANFTFGVGLAAGAVMMVIPAYLYHDHEMHDVTLIG
                     ELLAIAAISICLLFIVVDLGRPDRFWHIMPGIGRFNWPVSMLSWDVVVLNGYLLINLHI
                     CGYLLYMRFLGRKPRKQWYLPFVFLSIFWAISIHSVTAFLYSGLGGRPFWNSALLAPRF
                     IASAFITGPAFVIVLLQVIRRFTGLPIGEGPLRTLTSVMRVTVLLNLFMLGSELFTAFY
                     TGGSHATAVRYLFFGSHGHHALVPWIWTAVALNIASAVLVHLPATRRHVGLLNLACALA
                     FAGVWIEKGMGLIIPGFVPSTLHEVVEYVPTLTEWKITAGIWAVGLMVLTVAVKVALPV
                     LSGQLAASHGHGSEETTEARRAA"
     gene            10001..10633
                     /locus_tag="AA314_RS35515"
     CDS             10001..10633
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012967.4"
                     /locus_tag="AA314_RS35515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-homoserine-lactone synthase"
                     /protein_id="WP_047862734.1"
                     /sec_met_domain="Autoind_synth (E-value: 6e-18, bitscore:
                     64.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQVHIIHAGNRHLYEDTIEQHFRIRHDICVGEMRWMELERPDGR
                     DVDQFDTDKAVYLLGLEPERGVVAGSRLLPTLEPHLLGNVFPELANIRGVPHAPDIFEW
                     TRFFVHPARRESNRPSKAAGIIQCAIVEFCLSQNIRKISGVCEAHWLPRLQALGWNPCL
                     LGEPMRKDSMTIVGLSTDMTTEALERTRSAYGIIGSVIAPVSIPFNR"
     gene            10790..11917
                     /gene="hppD"
                     /locus_tag="AA314_RS35520"
                     /old_locus_tag="AA314_07270"
     CDS             10790..11917
                     /EC_number="1.13.11.27"
                     /GO_function="GO:0003868 - 4-hydroxyphenylpyruvate
                     dioxygenase activity [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hppD"
                     /inference="COORDINATES: protein motif:HMM:TIGR01263.1"
                     /locus_tag="AA314_RS35520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07270"
                     /product="4-hydroxyphenylpyruvate dioxygenase"
                     /protein_id="WP_211276565.1"
                     /transl_table=11
                     /translation="MRIVENRFTDAGPVESTIQNVAHLELWVGNARQAAHYYCRGFGFS
                     LVAYAGPETGVRDRASYVVRQGRCCLVLTAALLPDSCIAEHVHLHGDGIRDVAFMVTDA
                     AKAFRHAVERGAVPVAEPWEETDAHGTLRKASIASYGGLIHTFVEHRDYKGCFAPRFLA
                     AVPADDPLLPVGLFAIDHVVGNVERGQLEFWTRYYEETLGLARRQHFDDETISTPLTAL
                     TNTVLSSTDEQVKLLLNEPGRGTKRSQIEEYLLFNGGPGVQHVAFATRDIRRSVRALRA
                     RGIEFIHVPATYHEALRPPLSDNSLDLEEFQELGILADRDAHGHLLQIFTRLPQDRPTL
                     FFELIERRGCNGFGAGNVRALFAAFEREQAQRGNL"
     misc_feature    10865..10867
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11836..13590
                     /locus_tag="AA314_RS35525"
                     /old_locus_tag="AA314_07271"
     CDS             11836..13590
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF006002.0"
                     /locus_tag="AA314_RS35525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07271"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_082175521.1"
                     /transl_table=11
                     /translation="MQRVWSGEREGVVRRVRTRTSSARQSLAPTTTPMTRPHTGHPVVI
                     VGAGPVGLTLASFLARFAVPTMLLEAGAPHRRIGSRAIFVQRDVLEILERIGCGRALTD
                     GALSIQRGHTYFQERLLYTTGFSRDENDVFPPFVSVPQTRTEEVLLAQLQRHGGVDIRW
                     GHEVQPGLIEDEEGVTLTVSGPSGVETLRAAYVVGCDGPGSVIRKSMGVGYEGQSHGDK
                     FLIVDLELHGELMSLERHFHFDPSFNPGRQVLLIPQPGGVWRIDFQVPFETELASERAS
                     GKLDERIQKVLGDRRYELRWVSLYQFHQLVARNFQRGRVFIAGDAAHLMSPFGARGMNS
                     GIADAENLAWKLWRVLSGQASAALLGTYEHERRAAALENIRITTRTMRFMVPPTPEERV
                     ERDQILRRSVESPEARALVDSGKLYTPFTYEDSPIVLRAGASAAVTSRLGAIAPDAPCR
                     VHGNDSVTRLRDLVGNGFVGLYLARDAEEARFWVRTVRQEAAGTAIFFAVVVDTNIEAR
                     DLEGCAVIDTAGRIREAYGPRGTLSILRPDGHIAAVRSEARPENLRALVDFASGADLGT
                     PTRTKEGI"
     gene            13590..14774
                     /locus_tag="AA314_RS35530"
                     /old_locus_tag="AA314_07272"
     CDS             13590..14774
                     /EC_number="1.11.1.5"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015131.4"
                     /locus_tag="AA314_RS35530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07272"
                     /product="cytochrome c peroxidase"
                     /protein_id="WP_047859133.1"
                     /transl_table=11
                     /translation="MRTDRKGIAALTLVLQMAGCADVDEGGESFREERFETSETAVRDT
                     PGRALFNDATFGGNGRTCRTCHSSGTGTVSPEEARLRFSRNPNDPLFLHDGLDDGVRGV
                     TRMLERATFRIQLPLPPNVVLAHSPARSVVVLRASLSTNNVALENTLMNDGREATLETQ
                     ALGAIHGHAQNTLAPTPGQLEAIAEFERSREFFTSARLWAYANGGAEPGLPVGRTQAER
                     RGRRFFENIPFAPNAAGTHMSLDGICAHCHSGPMLNTANGHGPFPVNTRFTTAGVSELN
                     RSGNTVRTFVFTLADGTSTEVTSPDPGRALITGKAADANLFKTPSLWGINRTAPYFHDH
                     SARDFDELLDHYQAFFDTAPTPVPVAHFTHQDREDLKAFLRLLDQPPSAHSDQP"
     gene            15010..15900
                     /locus_tag="AA314_RS35535"
                     /old_locus_tag="AA314_07273"
     CDS             15010..15900
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS35535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_07273"
                     /product="hypothetical protein"
                     /protein_id="WP_047859134.1"
                     /transl_table=11
                     /translation="MLRTLFRPSLLLACVLASGCGPSAVEPKPTANQDTQAQALRIRIP
                     RWLKIVVSDMVGAASGAQTGAEIGGILGPEGAAAGAVIGGIIGGVQASTEAAARQTTTL
                     GVSAGSKPSSDPANARNPFDHIGQHHNAVLDTSVGIIGPGGCIPNPFPFPFPRDRTQGP
                     LWDYSLKTLNAPPELMKLPELEASWHKTLDFVVSVEQAEDLELAIADGVKSGLLTPPVG
                     ERLISYVNTVAPLDTDKLLEVTKAIEEETLADKELGEQDRQSLLSAYSVARHSAAYWGE
                     QAAQQESSPWCGCSK"
     gene            complement(15907..17094)
                     /locus_tag="AA314_RS35540"
                     /old_locus_tag="AA314_07274"
     CDS             complement(15907..17094)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631365.1"
                     /locus_tag="AA314_RS35540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07274"
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="WP_245682689.1"
                     /transl_table=11
                     /translation="MRHALKTRMAVLGAALGMFVLGSGQGAQGQALPKTDSGIDIQKVT
                     PEGKLPGKAVPYYIRNGEGERYLVGGLVADLVARGEDTQDLFETAVLTGGRDANLPLHT
                     HARTHEALLVLDGEVELWLGKEHHLLIRGDFASIPEGTPHALKMRSHRTQLISWSTGKE
                     MSPFYMALGQPYAGHVQPPEVNPELSGELLKKAEASADVRFERKAPGRSTPQRVSNGKL
                     PDKKIPYVLASGEGERLVAGEQLFSFLGDQQTTGGRFLIVMTEGPAGEMIPAHFHEKHT
                     ETFFCLDGSMNMRVNGEQLTLAPGDFVHAPARTIHAYQLKSHYTRMVGLLTPGLFEPFF
                     RTLGDPYAGYVYPQTPPPFRFDRVLSKLNELDLKLVGAPPRSDRACPRCGGRLGV"
     gene            17190..18074
                     /locus_tag="AA314_RS35545"
                     /old_locus_tag="AA314_07275"
     CDS             17190..18074
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="AA314_RS35545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07275"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_047859135.1"
                     /transl_table=11
                     /translation="MELRHLRYFVAVAEELHFARAARRLSIVQPALSMQIKSLEEELGT
                     RLLERTRRHVELTEAGRLFLEEARRTLEQAERAKRVATRAGQGELGRLGIGYSVNAAYS
                     GVLARTLKAFRQRAPDIELLLHELHPFDQLEALLEGRIQLGFLTAPALPIPPELVTVQV
                     GAWPLMVALPSDHPLCARARVPVELLVEESFVDYTGSKGEQGLPAMQRIGGFVPRIRYH
                     STNIMAVISLVAAGLGVALVPSSIVSLNIGGNVVYRPLTGVSGLMEMSVAYRRNEKAPA
                     VRAFLKVIQEQSG"
     misc_feature    complement(18138..18153)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.63"
                     /tool="antismash"
     misc_feature    18139..18152
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.87"
                     /tool="antismash"
     gene            18144..18800
                     /locus_tag="AA314_RS35550"
                     /old_locus_tag="AA314_07276"
     CDS             18144..18800
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637348.1"
                     /locus_tag="AA314_RS35550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07276"
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="WP_082175522.1"
                     /transl_table=11
                     /translation="MSPTRWWHRLWGQEPKPPEPSKTPEPPQTPRTPRTPQTLEVAPLP
                     GWSRSKEVERMLRDRIIMIGTPIDDAIANVVVAQLLFLESEDPEAGISLYLNSPGGSVT
                     ASLAIRDTLEYVKPPVSTICMGRCHGTAALLLACGARGQRISLPQGRIGIVPLEVRAGT
                     ADDPQIRHTLDTIVHLFAECTGQTRETVRKDLTHGREFSPESAMAYGLIDSVVNR"
     gene            18950..19774
                     /locus_tag="AA314_RS35555"
                     /old_locus_tag="AA314_07277"
     CDS             18950..19774
                     /NRPS_PKS="Domain: PKS_KR (13-174). E-value: 3e-12. Score:
                     38.7. Matches aSDomain:
                     nrpspksdomains_AA314_RS35555_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378116.1"
                     /locus_tag="AA314_RS35555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_07277"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_047859136.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-31, bitscore:
                     108.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASSKQGNTRQFAVVTGASSGIGYELARQFAQNGFDVLIAAEDDS
                     ITEAARSLANGAHIESLKVDLATYDGVEQLYAKIQSLGRPVDAIAINAGVGVGGEFTET
                     KLEDELNLIQLNVTSAVHLAKRVARDMVKRGSGRILFTSSVAAIMPAPFEAVYGASKAF
                     LLSFSEALRNELADAGVSVTALLPGPTETNFFHRAGMDDTRVGQQKKDDPAQVARQGFK
                     AMMAGEQKVFAGSVKTRLQAAVARVLPDPAKVQMHRLMSEPGSGSDPEPEHK"
     CDS_motif       18989..19051
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AA314_RS35555_0001"
                     /evalue="3.80E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="AA314_RS35555"
                     /protein_end="34"
                     /protein_start="13"
                     /score="13.1"
                     /tool="antismash"
                     /translation="VVTGASSGIGYELARQFAQNG"
     aSDomain        18989..19471
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AA314_RS35555_PKS_KR.1"
                     /evalue="3.00E-12"
                     /label="AA314_RS35555_PKS_KR.1"
                     /locus_tag="AA314_RS35555"
                     /protein_end="174"
                     /protein_start="13"
                     /score="38.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVTGASSGIGYELARQFAQNGFDVLIAAEDDSITEAARSLANGAH
                     IESLKVDLATYDGVEQLYAKIQSLGRPVDAIAINAGVGVGGEFTETKLEDELNLIQLNV
                     TSAVHLAKRVARDMVKRGSGRILFTSSVAAIMPAPFEAVYGASKAFLLSFSEALRNE"
     CDS_motif       19319..19378
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AA314_RS35555_0002"
                     /evalue="5.50E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="AA314_RS35555"
                     /protein_end="143"
                     /protein_start="123"
                     /score="9.4"
                     /tool="antismash"
                     /translation="AKRVARDMVKRGSGRILFTS"
     misc_feature    complement(19965..19980)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.99"
                     /tool="antismash"
ORIGIN
        1 gcccgcccga gccgccggag tcagccgcgg cactgctcga caaggcggag gaggcccccg
       61 aggacgtgct ccagctgctc gacgtcgcga ggacgcgctg gcccggggag cgggcgacgc
      121 tcgtgcgcgc ccaggcgaag gcgctggagc ggctgggccg cggcgaggag gcggaggtgg
      181 cgctgcgctc gctgctggac gcggacgcgc accccacgcc cgacgtcgtg cacgagctcg
      241 gcatgaacct gctcgagcgg aggcgcttca cggagctgca cgctctcgtc gactcggttc
      301 tggccgcgtc cagcgacacg cccctgcgcg tggaggcgta ccggctgcgg gcccgggccg
      361 cgctcgagtc gggcgagaag gccgcggcca aggcgcccat gcgcgcgatg ctggagctcg
      421 acccggagct gagagggacc accctgatgc tcgcggcggt ggagcgcgac acgggcgagc
      481 gggaacaggc cctggcgcgg ctggacgcgg ccgtggcccg ctggccggag cccgggccgc
      541 acgactggga ccgggtgctc gtggccaccc tgctcgggcg ctgggacgtg gtgcgtgctt
      601 ccgctgaacg gctgggcttc aagctgtccg gggagccggg cccggtggag gaggagtggg
      661 aggcgtgccg gctgcgctac accgagccgg acggcacctt cacggaggta tgggcgcggc
      721 gcaccggccc cgtcaccgcg cgcgtggtct ccatcgccat gcccgatgcc gcccagcacg
      781 tgggggacgt cgtggccttc gacgccacgc cgctcaacga gggccccgcc gagggacagg
      841 aggaggagca ctcctggctg taccccgtcg tggaggtgct ccgtccgggc aggtacagcg
      901 tcttcgcgct ggacggcgtg ggtccgggcg atgaggtcat cgagcggatg tacgagacgc
      961 tgacggcgtg cggggcgcgg ctgtcggtgc gcacctcgga gacgtaccag ttgatgacgc
     1021 cggacggtga ggaggtgccc ggcttctacg cgctgctggc cgtgccgccg gaggtggagc
     1081 tgggtgaggt ggaggcgggc ctgcgccggt gcgcggaggg gctgccgcat ccactgctgt
     1141 ggcccacgct gctggagaag ctggggcggg agcaggaggc gcaggcgcag cgcgcggtgg
     1201 cggaggagtg ggagatctcg ctgtgacgag gacgcggctg cgcgtctgga tgtccagccg
     1261 ctgaaggtgg catccagggc tcaaaagggc atgtcggttg tctcgacgac gagctctcca
     1321 cggttgatgc tggcggcgag cttctgcgcc agcttctgct gctgggtagc tgtcatttca
     1381 gcgaacaacc cgcgcaacgt agcaacctgc gcatctcccc aacgtcctgc gcgaagggca
     1441 tcctcgatca aacgctgccc gcgctcctgt gcggcgaggc ttgtgggcga taccccttca
     1501 tggacaatgg caggcggagt ggctttcgac gattcggaat tcaccatgga cgtggtgagc
     1561 tcctcacgga ggattctcct gaactccgcg ttcgaggacg caacgtccag ggccgccgcg
     1621 gtcgtgcctc cctggcatcg cacctgtgat tggagtgtgc tcagttgagc ggaaagagac
     1681 tcgattcgag cactcaaatc ctcgaacgcc tgcgctgatg actccgaggc gcgcgcaggg
     1741 gaactcatga ccagtgatgt gccatggccc agcgcccatc ccgtaacgag cgtgaaggga
     1801 atccacaact tgagggacga agtcatcggg aagcgctcct tgatgcgaaa cgctgacgcc
     1861 gggcaacaga cccggcgcat gcacgaactg acgctttcgg ttggtttgga accggctcag
     1921 acttccttcg gcttgtatcg cgagtcggga cgaacgctca ggccaatgca ggagccctgt
     1981 gcatcccaac tgaacgcgat atgcgcatcc gaagtcactg catccatcac ctggacgatt
     2041 tcaggctccg ccgaggagca agtaacggtg acattgctgg aattgcgcgc cgaacaccac
     2101 accgctcgag aagagcctgc agtggcactc acggtacaac caatatactg aagggtgtcc
     2161 gagctacccc tgacagtccc catcgttccc gaggcagtac cattgtcgcc cgaaaacacg
     2221 atggagactc ccgagccacc cttggcacct gcccacgcgg cagtgctcaa attcatcgct
     2281 gccatcagag caacaagggc tggaattctc gtgtatcgac tcatgagcat catctcccaa
     2341 gaaggggacg ccggttttcc agagtggaag accaggcacc tctggataca aacacacagg
     2401 tcccgaaaaa cagtctcagg cgcctgtgac tgggagtgtg gcaaatgagc tggaacgaat
     2461 caagaactgt cattgattga cccagcactc gactcgcggg cgatgcgcat gcgtgagaaa
     2521 cagtgggttc gccctgtttg cgtggaccgc aaaccttgtc aattcttgag aatgcagaac
     2581 cttctccgct aaatccggac gaagtgcggt acctgcgggc gctacccccc gagccggtgc
     2641 tcgatgcgaa tcaagcgaac accccggggg gtgtgcatca gcgtgtccca ccagttcgcg
     2701 ccctcatacc agtagcggat ctgcacaccg gccacgcgct tctcccggag cgccagctcg
     2761 gcctcgggaa gcgggacgga cttctcggag gccatcaacg cggcgctgcc cttgagcaac
     2821 acctcgtcca ccacggcaca gcgctggatg tcccgaaaca actgctccag ggtctccggg
     2881 ccgaggatcg cgtcctgcaa ccgcgggagc gcggcgttct cggcggagac attcgtgagg
     2941 cggatacctg tcgtcatgga cctggggcct gctggcgggg aggaaggaac tcgagggcgt
     3001 tgagcggagc cgggcacgcc tggacgcaga ggccacagcc gttgcaccgt gactccacga
     3061 cgctcggacg gcccgactcg atggcgatgg ccccctcgac ggggcagcgc tcggaacagg
     3121 taccgcagaa cgagccctgc catgcgaggc agagctgggg acgcacccgc acggtcatcc
     3181 cggccacagg cactcccatt cggcgggtgc tctcttgcgg aacggcgagc ccctcgcgca
     3241 aggagaacac cggcagctcc cggccggtca cctcacccga gcgggcacgg gaggaataga
     3301 acgcctcgag cgagaagccg ggctcgggcg tggcgggagc ggacacggga gccggtgcag
     3361 ccggaggacg gggctgcgcc tcgtgccggc gcaacccgag gaacgcacgg cggctgaggg
     3421 tgctctggga gctcatggcc gcgcctccaa ggccagaccg ggcccccctg ccccattgac
     3481 gcgctggtcg agccgcgccg aggagccatg gcactgctgg cagttctgcc gctcggggtg
     3541 cgaggtgcgc agcccgagga ggccgcgcgg gccgtggcag ctcgcgcaat cgtcccgcat
     3601 gagcgtcggg tggggcatgg tcggcggagc ccctggccac gcccgctcgc cctttccagc
     3661 cgaggccaaa ccgacgaagc gattgcccgg accctccttg tactgagcca acggacgagg
     3721 cgactccccc accacgtggc actgcgtgca gctctggtac ggcggatggc tgatcttcgg
     3781 agccacccgg ttgcccagct tcatgccctc gccatggcag gccagacagc cggggacttc
     3841 gcgctggtcg atctcatgcg gaatggtcgg cggcgccccg tcataggccc ggtggtcctg
     3901 tcgttgcgcc acggcccgtg cgcgctgctc ggcggtagcc accggcaggg gcttcaccgg
     3961 gaacggctct tccgccagcg cgtcgatggc tccctcgtac atgcgcgcat tggccccccg
     4021 ccgctgctcg cgcagctcgc tgtagctcgg agcacgctcg gcccgttgcg catggggatc
     4081 cgaggcaacc ggcctctccg gcatctccgg cgcgcggagg ccggcgaagt aaccggtggc
     4141 cgcgagcgcc accgccacgg cggcgcccac ctgaagccag cgcgcgccga gcccgctgcc
     4201 ctgtccaccc tcggggctca tccctgcttc tccgcgacga gctcacgccg tcgcacacgt
     4261 gccgcgcact tcttgtaatc gggctgcttg gagaacgggt catgctcgtc gagggtgagc
     4321 cagttgatga gcagccgctc gtcgaagaat gggacgaaga gcgagccctc cggcggctca
     4381 ccccggccgc caatccacac gggcaggtcc aacttcccgc gccgcgtctc caccgtcacc
     4441 tggtccccgt tgcccactcc gagccgccgc gcatccgcgc ggttcatctc cacataggcc
     4501 tggggcatgg cgcgctggag ctgaggaatc cgcatggtca tcgtgcccga gtgccagtgc
     4561 tcgatgacac ggccggtgca cagccagaag gggaactcgg cgtcggggga ctcgggagga
     4621 ggctcgtagg ggctgaacca gatctgcgcc cggtcatcgt gcgtggtcga gtggtagaac
     4681 tggatgtcgc gccccttctt cacatagggg tcatcgaagc cagcgaagcg gaagcgcgtc
     4741 tcgcgccagc tgccgtccgg ctgctgcacc acgggccagc gcaggccgcg cgccttcacg
     4801 tactcctgat agggcgccag gtccttgtgc ttgatgcggg tcgtcttccg gtactcctcg
     4861 aagaggtgct catccacgtt gacgtcgtag tagtgggcga agtcccagag gggcacgggc
     4921 ttgccgtcct tgcccttcac ctcgaagagg aagcggccgt ccttgtcctt catcccctcg
     4981 aagccaagct cgaggagccg gtgggccacg gcgatgagtt gccaggcgtc atcacgggcc
     5041 tgaccgggag gcttcaccat cttgaaccac tgctgggtgc ggcgctcgga gttgcccacc
     5101 atgccgttct tctccaccca catggccgag ggaaggatga ggtccgcgat gcgcgcggtg
     5161 gccgagggat agacatccga gacgatgagg aacttgtcgg cgagcttgcg gctggggtcc
     5221 accagcttgt gggtgttggg cagcgtctgg gcggggttgg tgacctggac ccagatggtg
     5281 tggatgtccc cgccctgctc ggtgggcgtg gagaagcgct tccacatctc cagggtgtgg
     5341 tagccgggct tgtcgtggag gcggcccttg gggacgttcc agatctcctc catctgggcg
     5401 cggtgctcgg ccttggccac cacgcgtccg ccggggagtg catgggcgag cgtgcccacc
     5461 tcgcgcacgg tgccgcacgc ggagggctgg ccggtgagac tggtgggcgc gtctcctggc
     5521 ttgccgaagt gcccgctgag caggtggagc ccgtggacca ggttgttgat ggccgtgccc
     5581 cgggtgtgct ggttcatccc catgcaccac aggctggtga tgcgcacgtc gcgccggccg
     5641 aacaggtccg cgagcatccg caggtccttc gccggaacgc ccgagagctc ctccaccttc
     5701 tccggggtgt agggctcgag cagctcgcgg tactcctcga aggtgatggc cttgccctcg
     5761 agcgccgcgg gctcgctggg ggcgcggaag gcacagttgg cctcgacgaa ggccttgtcg
     5821 taggtgccgt tctccaccag caggtgggcg atgccacacg cgatggccag gtccgtgttc
     5881 ggcttgaagc gcagcgagtg gtcgcagaaa ccgctggtgc gtgtcttgcg cgtgccgatg
     5941 tcgatgagcg tcaccttctc cccgcgcgag cggcggtcga tgacacgcga gaagaggacc
     6001 gggtgcatct cggcggggtt gttgccccac atgatgagca cgtcgcaggc atcgaggtcg
     6061 tcgtagcaac cggcgggctc gtccacgccg taggtggcga ggaagcccgt caccgccgag
     6121 gccatgcaca gccgcgcgtt ggcatccagc tggttggagc ccaggccgcc cttgacgaac
     6181 ttcgaggcgg catagccctc ggggatggtc cactggccgc tgccgtagag gccgaagccc
     6241 ttggggtcct tcagcacacg gcgggcgacg atgtcgatcg cctcctccca ggagatgggc
     6301 acgtgcgtgt cgcccttctt gaggagcggc gtggtgagcc ggtcgctccc atagagggcg
     6361 agccccacgt ggtagccctt cacgcacagc aggcccttgt tcaccggcgc ctgctgatcc
     6421 cccgcgatgg ccaccacctt gccgttctgc acgcccacct gcacgtgaca gccggtgccg
     6481 caaaaacggc agggggcctt gttccactgc acgccctgtc cagcgggagc agcggctggc
     6541 ggagttccgg cagccttgtc ctggccatac gcgaggcggc tcgcggccag cgtcgccgcc
     6601 gtcatggccg tgcccttgag gaagtcccgg cgatccatgg tcagcgctcc tcctcggaga
     6661 aatccaccat cacgacgtcc acgaagctca ctcccgggag gtccctcaag gactcggcga
     6721 gcgcctcccc ttcgggaagg ctgccggtct ccgtcaccac cggcagccag cgctcctcca
     6781 gggggggccc cagggtgatg cgcggatcgc gagcgacttc acgaagcacg ctcgccctca
     6841 gttcgggaga agcgtcgagg gtgagtacca ggctgctgat gggcatacag gctccgtcca
     6901 ttcgggcagg acccccagga gcaagaggcg gaccacccgg gcgcgcgagg ggcgacggcg
     6961 gaggcgacgc aaagcctgcg cccaaatctg tttttctgat gcaggttttt cgcgctcgag
     7021 cgggcagctc ggcacctctt cacggcgggc gcacagggaa gagccgtgct ggcacggaca
     7081 ctgctttgcg caagcctccg tggagaaccc tctcgacaga tggatgcgcc cggccctggc
     7141 cgccgtgctg ctcgcgttcg gcggctgcgg gaaggatcag cccgctcgct tccaaccgcc
     7201 cccgggggcg cccaccggca aggagacgct ccaccagccg gcgaagctca cctccgtgga
     7261 gagcggccag acggacgcac tgggccggcc gcttcgcgtg tcgtgcgaga gctgccactc
     7321 gctgcgtgag acgaagccca tgccctcgcg gcccgaggag ctgaaggagt tccaccaggg
     7381 cctccagttc cgccatggcg agctcgcctg cacctcctgc caccaggcca accagccgcg
     7441 cacgctgcac ctggccacgg gcgagccgct gccgatgccg gaggcggtga cgctgtgcgc
     7501 gcagtgccac gggccgcagt accgcgactt caaggcgggg gcgcacggcg gcatgacggg
     7561 ctactgggat ctgtcgaggg gagaccgcac gcggaaccac tgcgtgagct gccacgatcc
     7621 gcactcgccg aaatacgcgg gcgggcatcc ggtgatgcct ccgcgccacc cgtccaccca
     7681 gggcgagccg gacaacaagg aggcccgagg ccatgagtga catcctctcc cgccgcaccg
     7741 tgatgaaggg cgcaggggcc acgctcgggg ccgcggcctt cgcgcacgcg atggctccgc
     7801 tcaccgagtg gacgcaggac ctgagcgtcg atgaattcct ccagaagcac tacaaggagc
     7861 tgacgcgcga cgagatggcg cgaatcctgg tccacctgaa ggccgaggcg aaaaagacat
     7921 acggccggga cgtggacatc caggacctgc cgccgcagga gggcgtgtcg ttcggctacg
     7981 cgctgaacct gagcgtgtgc atcggctgcc gccggtgcgc cgaggcgtgc caccaggaga
     8041 acaaccacga ccggagcacg ggcaactcgt acatccgggt gctggagatg cagcagggca
     8101 gcctggatct ggagcacggc aacgcgaact acgaccaccc ggtgccggcc gaggggaagt
     8161 actacctgcc agtgcagtgc caccagtgcg acaacgcgcc gtgcgtgaag gtgtgcccgg
     8221 tgcaggcgac gtggaaggag tcggacggca tcgtggtggt ggactacaac tggtgcatcg
     8281 gctgccggta ctgcgaggcg gcgtgcccct accacgcgcg gcgcttcaac tggacgaagc
     8341 cggagattcc gcccgaggag ctcaacccgg accagggcta cctctccaac cgcgtgcgtc
     8401 cgcagggcgt ggtggagaaa tgcaccttct gcctgcaccg cacgcgggcg ggccggctgc
     8461 cggcgtgcct ggaggcgtgc cccacggggg cgcgggtgtt cggcaacctg ttggacccga
     8521 agagccccat ccgctgggtg ctcgagaaca aacgcgtctt cgtgctcaag gaagagctcg
     8581 ggacgcggcc ccgcttcttc tacttcttcg acaagtgagc catggccgcc acccgacacc
     8641 tgctcgacta cccgcggttc ctgggccgcc tcctgtggat gagcacggac gggagctggc
     8701 gcttctacac gtggatgacg gtgctcaccg cgattgccct ggtgggtgcc aatgcctggg
     8761 cgcaccagct ggccgggggc atggccctca cggggatgag tgaccacgtc tcctggggcc
     8821 tgtacatcgc caacttcacc ttcggggtgg gcctggcggc gggcgcggtg atgatggtca
     8881 tccccgcgta cctgtaccac gaccacgaga tgcacgacgt cacgctgatc ggcgagctcc
     8941 tggcgatcgc ggcgatctcc atctgtctgc tgttcatcgt ggtggacctg gggcgtccgg
     9001 accgcttctg gcacatcatg ccagggattg gccggttcaa ctggccggtg tccatgctct
     9061 cctgggacgt ggtggtgctc aatggctatc tgctcatcaa cctgcacatc tgcggctatc
     9121 tcctctacat gcggttcctg ggccgcaagc cgcgcaagca gtggtacctg ccgttcgtct
     9181 tcctctccat cttctgggcc atcagcatcc acagcgtgac ggcgttcctc tacagcgggc
     9241 tcggagggag gcccttctgg aactcggcgc tgctggcgcc acggttcatc gcgtccgcgt
     9301 tcatcacggg cccggcgttc gtcatcgtgc tgttgcaggt catccgccgc ttcacggggc
     9361 tgcccatcgg cgagggcccg ctgcgcacgc tgacgtcggt gatgcgggtg acggtgctgc
     9421 tcaacctgtt catgctgggc tcggagctgt tcaccgcctt ctacacgggc ggctcgcacg
     9481 ccacggcggt gcgctacctg ttcttcggct cgcacgggca ccatgcgctg gtgccgtgga
     9541 tctggacggc ggtggcgctc aacatcgcct cggcggtgct ggtgcacctg ccggccacgc
     9601 ggcggcacgt ggggttgctc aacctggcgt gcgcgctggc cttcgcgggt gtgtggattg
     9661 aaaagggcat gggcctcatc atccccggct tcgtcccgag caccctgcac gaggtggtgg
     9721 agtacgtacc cacccttacg gagtggaaga tcaccgccgg catctgggcc gtcgggctga
     9781 tggtactgac ggtggcggtg aaggtggcac tgccagtgct gagcggccag ctcgcggcct
     9841 cgcacgggca tggaagtgag gagaccacgg aggcacggcg agctgcctga gcccacacgg
     9901 gttcgaagct cgaagctgaa ctcttctgat gtgctggctt atcctccgga agctcacctt
     9961 ccgtcctctc cagtggggag gcactttcaa atccggggtt atgttccagg ttcacatcat
    10021 tcatgccgga aaccggcatc tctacgaaga caccatcgag cagcactttc gcattcgtca
    10081 tgacatttgt gtcggcgaga tgcggtggat ggagctggaa cggcctgatg gccgcgatgt
    10141 ggatcagttc gatacggaca aagccgtcta cctgttgggg ctggagccag aacgaggggt
    10201 tgtagctggt tcacggttgt tgccaacgct ggagccgcac ctgctcggca acgtcttccc
    10261 agaactcgcg aacatccgag gggtaccaca cgcacccgat attttcgaat ggacacgatt
    10321 cttcgtccat ccggcgagac gcgaatccaa ccggcccagc aaggccgctg gaatcatcca
    10381 atgcgccatc gtcgaatttt gtttgtcgca gaatatccgg aagatcagcg gagtatgtga
    10441 agcccactgg ctccctcgtc tccaggccct gggctggaat ccatgcctcc tgggagagcc
    10501 gatgcgcaag gacagcatga caatcgtcgg gctttccacg gacatgacca cggaagccct
    10561 cgagagaaca cgctcggcct acggaatcat tggaagcgtc attgcacccg tatccattcc
    10621 cttcaaccgg tagggatggc aacccctccc agtgcatccc ttcgaaccaa cctggagcac
    10681 ggggaccccg agattatcgc atcggtaaca ggccaggcct gtcgaggcct ccctgccata
    10741 cacccgttca ctcttccatg ttacccagac atggggggga acgacacccg tgcggattgt
    10801 cgagaatcgt ttcacggacg caggcccggt agaatccacc atccagaacg tcgctcacct
    10861 cgaattatgg gtagggaacg ctcgacaggc agcgcactac tactgcaggg gatttgggtt
    10921 ttccctggtg gcgtacgccg gacctgagac aggagtgcgt gacagggcgt cctatgtggt
    10981 gcggcaggga cggtgttgcc tcgtcctcac cgccgcgctt ctcccggact cctgcatcgc
    11041 ggagcacgtc cacctccacg gtgatggcat tcgagacgtc gccttcatgg tcacggacgc
    11101 cgcgaaagcc ttccggcacg ccgtcgaacg cggcgctgtt cccgtcgccg agccgtggga
    11161 ggaaacggac gctcacggaa ccctacgaaa ggccagcatt gcctcgtatg gcggcttgat
    11221 tcacaccttc gtcgagcacc gcgactacaa gggctgcttt gctccgcgat tcctggcggc
    11281 agttccagcc gatgaccctc tgctacccgt cgggctgttc gccatcgatc atgtcgtggg
    11341 caatgtcgag cggggccagc tggaattctg gacccgttac tatgaggaga ccctcggact
    11401 cgccaggcgc cagcatttcg atgacgagac catttccact cccctcaccg ccctcacgaa
    11461 cacggtgctg tcctcgacgg acgagcaggt gaaattgctg ctcaatgagc caggccgtgg
    11521 aacgaagcgc tcgcagatcg aggagtacct gctcttcaac ggaggtcctg gtgtgcagca
    11581 cgttgcgttc gcaacccgtg acatccggag gtccgtgcgg gctctccgcg cacgcggaat
    11641 tgagttcatc cacgtcccag ccacctacca tgaggcgctg cgtccgccgc tctccgacaa
    11701 cagcctcgac ctcgaggagt tccaggaact cggcatcctg gccgatcgcg atgctcacgg
    11761 ccaccttctc cagatcttca cccgcctgcc ccaggaccgg cccaccctct tcttcgaact
    11821 catcgaacgt cgtggatgca acgggtttgg agcggggaac gtgagggcgt tgttcgccgc
    11881 gttcgaacga gaacaagctc agcgcggcaa tctctagcgc ccacgacaac gcctatgacg
    11941 aggccgcata ccgggcatcc cgtcgttatc gtcggcgccg ggccagtcgg gctcaccctc
    12001 gcgtcattcc tggccaggtt cgcggttcct accatgctgc tcgaagccgg ggcacctcat
    12061 cggcgcatcg gctccagagc catcttcgta caacgtgacg tgctcgagat tctcgaacgg
    12121 atcggctgtg gccgtgcgct cacggacggc gccttgtcga tccagcgagg acatacctac
    12181 ttccaggagc gcctgctcta tacgaccggg ttctcccgtg atgagaacga cgtcttccct
    12241 cccttcgtca gcgtccctca gacacggacc gaagaagtgt tgctcgcgca gctccagcga
    12301 catggagggg tcgacatccg ctggggccac gaggtgcaac cgggtctcat cgaagacgag
    12361 gagggcgtca ccctcacggt gtccggcccc tccggcgtcg agaccctgcg tgccgcctat
    12421 gtcgtgggct gtgacggacc tggctccgtc atccgcaaat cgatgggagt gggctacgag
    12481 ggacagagcc atggcgacaa gttcttgatc gtcgatctgg agctccacgg ggaactgatg
    12541 tcgctcgagc ggcacttcca cttcgatccg agcttcaacc ccgggcgcca ggtgctcctc
    12601 attccccaac cgggtggggt gtggcgcatc gacttccaag taccgttcga gacagagctc
    12661 gcctcggaga gggcctcggg aaagctcgac gagcgcattc aaaaggtgct gggagaccgt
    12721 cgctatgagc tccgatgggt ctcgctctat cagttccacc agctcgtggc ccggaacttc
    12781 cagcggggtc gagtgttcat cgcaggcgac gccgcccacc tgatgagccc attcggtgcg
    12841 aggggcatga attcaggcat cgccgacgcc gagaacctgg cctggaagct gtggcgggta
    12901 ctctctggac aggcctccgc ggcgctgctt ggcacctacg aacacgagag gcgggcagcc
    12961 gcgctcgaga acatccgaat caccacccgc acgatgcgtt tcatggttcc cccgacgccc
    13021 gaagagcggg tggagcgcga ccagatcttg cgccgcagcg tcgaaagccc cgaggcgcga
    13081 gccctcgtgg actcgggcaa gctctacacg ccgttcacgt acgaggactc ccccatcgtc
    13141 ctgcgtgccg gggcgagcgc ggctgtcaca tcacggctcg gggctattgc gccagacgct
    13201 ccctgccgtg tgcacgggaa tgacagcgtt acccggcttc gcgacctcgt aggtaatgga
    13261 ttcgtggggc tgtatctggc ccgagacgcg gaggaggcac gtttctgggt gagaacggtg
    13321 cgccaggagg ccgcgggcac agcaatcttt ttcgccgtcg tcgtggacac gaacatcgaa
    13381 gcaagggatc tcgaagggtg cgcagtcatc gacaccgccg gccgcattcg agaggcatac
    13441 ggcccccggg gaacactctc catcttgcgc ccggatggac acatcgccgc tgtgcgctcc
    13501 gaggcaaggc cagaaaatct ccgcgcgttg gtcgacttcg cctcgggtgc tgaccttgga
    13561 actcctacac gaacgaagga aggcatttga tgcgaacgga ccgcaagggc atcgcggcgt
    13621 tgacactcgt gttgcagatg gcgggctgcg ccgacgtgga cgagggagga gaatccttca
    13681 gggaggagcg cttcgaaaca agtgagacag cggtgcgcga cacgcctggg cgcgcgctgt
    13741 tcaacgacgc gacgttcggc ggcaatggac ggacatgccg cacgtgtcac tcttcaggca
    13801 ctggcaccgt ctcgcccgag gaggcacggc tgcgcttctc tcgcaatccg aacgaccctc
    13861 tcttcctcca tgatgggctc gacgatggcg tgaggggtgt cacgcggatg ctggagcgcg
    13921 cgacgttccg gatccaactg ccactgccac ccaatgtcgt actggcacac tcgccagcgc
    13981 gcagcgtcgt ggtgctccgc gccagcctga gtaccaacaa cgtcgcgctc gagaacacgc
    14041 tgatgaacga cgggcgcgaa gccacactcg agacacaggc tctcggagcc atccacggac
    14101 atgcgcagaa caccctcgca cccacgcccg gacagctcga ggccatcgcc gaattcgagc
    14161 gctcccgcga gttcttcacc tcggcccggt tgtgggcgta cgccaacgga ggtgccgaac
    14221 ccgggcttcc ggtgggccgc acccaggcgg agcgccgcgg ccggcgcttc ttcgagaaca
    14281 tccctttcgc accgaacgcg gccgggacac acatgagcct cgacggcatc tgtgcgcact
    14341 gtcattcagg cccgatgctc aacacggcga acggacacgg gcccttcccg gtgaacactc
    14401 gcttcacgac agcgggagtc tcggagctca atcggtccgg caatacggtc cgcacgttcg
    14461 tgttcaccct cgccgacggc acgtccaccg aggtgacctc gcccgatcct ggccgcgcac
    14521 tgatcaccgg aaaggccgcc gacgccaacc tgttcaagac gccttcgctc tggggcatca
    14581 atcgaacagc gccgtacttc cacgaccact cggcacgcga cttcgacgag ttgctcgacc
    14641 actaccaggc attcttcgac accgccccga caccggtgcc cgtcgcgcat ttcacccacc
    14701 aggatcgcga agacctcaag gccttcctcc gcctgctcga tcagcctcca tcggcccatt
    14761 cagaccagcc ctgagcggcc agcccgcggc ctcgcacgcc gcgtcgcacc ccacacgtga
    14821 atcgggaaac aacatctccg cccccggttt gtagcacttg gggcaacaaa ggacgcccgg
    14881 acttcaccag tctcagagga aagcccggtt tggcccggtt cctgctcttg agagggacac
    14941 gctcggcgag ttcgcccagc caccgtgacg ctctggcttc acggtccccc cacaagaaga
    15001 ggacccccca tgcttcgcac cctgttccgt ccctcccttc ttctcgcctg cgtcctcgcg
    15061 tccggttgtg gccccagcgc ggtggagccc aagcccaccg cgaaccagga cacccaggcc
    15121 caggccctcc ggatccggat tccgaggtgg ctcaagatcg tcgtctcgga catggtgggt
    15181 gccgcttcgg gggcgcagac gggcgccgaa attggcggca tcctcggtcc cgagggcgcc
    15241 gctgccggag cggtcatcgg tgggatcatc ggtggagtcc aggcctccac cgaagccgct
    15301 gcccggcaga ccaccaccct gggcgtgagc gcgggcagca agccgtcgag cgatccggcc
    15361 aacgcccgca acccgttcga tcacatcggg cagcaccaca acgcggtgct ggacacctcg
    15421 gtgggcatca tcggcccggg gggctgcatt cccaacccct tcccgttccc cttcccgcgc
    15481 gatcgcaccc agggccctct ctgggattac tccctcaaga cgctgaacgc cccgccggag
    15541 ctcatgaagc tgcccgagct cgaggcgtcc tggcataaga cgctcgactt cgtcgtctcg
    15601 gtcgagcagg cggaggatct cgagctcgcc atcgccgatg gcgtgaagag cggactgctg
    15661 acgccgcccg tgggcgagcg gctcatcagc tacgtcaaca ccgtcgcgcc gctcgacacc
    15721 gacaagctgc tcgaggtcac gaaggccatc gaggaggaga cgttggcgga caaggagctg
    15781 ggggagcagg atcgccagag cctgctgagc gcctactccg tcgctcgtca cagcgcggcg
    15841 tactggggcg agcaggccgc ccagcaggag tcctcgccct ggtgcggctg cagcaagtaa
    15901 ccccctctac accccgagcc tgcctccaca ccgggggcag gcccggtcac ttcgtggggg
    15961 cgctccgacg agcttcaaat ccagctcgtt cagcttcgag aggacccggt cgaacctgaa
    16021 gggcggaggt gtctggggat agacgtaccc ggcgtaggga tcgcccagcg tgcggaagaa
    16081 cggctcgaag agccccgggg tcagcaggcc gaccatgcgc gtgtagtggc tcttgagttg
    16141 gtaggcgtga atcgtgcgcg cgggcgcatg gacgaagtct cccggagcca gcgtcagctg
    16201 ctcgccattg actcgcatgt tcatggagcc atcgaggcag aagaaggtct ccgtgtgctt
    16261 ctcgtggaag tgggccggga tcatctctcc cgccgggccc tcggtcatga cgatgaggaa
    16321 cctgccgccc gtggtctgct gatcaccgag gaaggagaag agctgctcac ccgcgaccag
    16381 ccgctcgcct tcaccggagg cgaggacata gggaatcttc ttgtcgggga gcttgccatt
    16441 gctcacgcgc tggggcgtgc tcctgcccgg cgccttgcgc tcgaaacgga cgtcggcgct
    16501 ggcttccgcc ttcttcagca actcgcctga gagctcgggg ttgacctccg gcggctgcac
    16561 atggcccgcg tagggctggc cgagcgccat gtagaacggg ctcatctcct tgcccgtgga
    16621 ccaggagatc aactgggtcc ggtggctccg catcttcaag gcatgcggcg tcccttccgg
    16681 gatgctcgcg aaatcgcccc ggatcagcag gtggtgctcc ttcccgagcc agagctcgac
    16741 ctctccgtcc aggacgagca gggcctcgtg cgtgcgagcg tgggtgtgca gcggaaggtt
    16801 cgcgtcccgg cctcctgtca gcacggcggt ctcgaagagg tcctgggtgt cctctcctct
    16861 cgcgaccagg tccgcgacga gccctcccac gaggtaccgc tcgccctcgc cgttgcgaat
    16921 gtaatagggc acggccttgc ctggcagctt gccctccggc gtgaccttct ggatgtcgat
    16981 gccactgtct gttttgggaa gcgcctgacc ttgggccccc tggcccgagc cgagaacgaa
    17041 catccccagc gccgcaccca gcacggccat cctcgtcttc aatgcgtgtc tcattcgatt
    17101 ccgcctttgc gttcggggat gaagatggtt gggacggctt gagaaatcca atagattgaa
    17161 actccgcttt taatcatcgg gagtgatgaa tggagctgcg ccatctccgc tacttcgtcg
    17221 ccgtggccga ggagctgcac ttcgctcgcg cggccagacg gctgagcatc gtgcagcccg
    17281 cgctgagcat gcagatcaag tcactcgagg aggagttggg gacacggctc ctggagcgca
    17341 cccggcgcca tgtcgagctc accgaggccg gcaggctctt cctggaggag gcacgccgga
    17401 ccctggagca ggcggagcgg gcgaagcggg tcgcgacacg ggcgggacag ggtgagctgg
    17461 ggcgtctcgg gatcggctac tccgtcaatg ccgcctactc gggcgtgctg gccaggacgc
    17521 tcaaggcctt ccgacaacgt gcgccggaca tcgagctgct gctccatgag ttgcacccgt
    17581 tcgaccagct cgaggccctg ctggagggac gcatccagct cggcttcctc acggcccccg
    17641 cccttccaat ccctcccgag ttggtcacgg tgcaggtagg tgcctggccg ttgatggtgg
    17701 ccctgccctc cgaccacccg ctgtgcgcac gagcccgcgt cccggttgag ctgctggtgg
    17761 aggagtcctt cgtcgactac accggctcga agggggagca agggcttccc gccatgcaac
    17821 ggattggggg cttcgttccc cgcattcgct atcacagcac caacatcatg gcggtcatca
    17881 gtctggtggc cgcgggcctt ggcgtggcgc tggtcccctc gtccatcgtg tcgctcaaca
    17941 tcggcggcaa cgtcgtctac cgtccgctca ccggtgtgag cgggttgatg gagatgtccg
    18001 tcgcgtaccg ccgcaatgag aaggctcccg ccgtgagagc cttcctgaag gtcattcaag
    18061 agcagtccgg ctgaacagcc acccgcgcca cccccctgag cgggctatcc tccctggaac
    18121 ttccgctgga ggatgcctcg aacatgagtc cgactcgctg gtggcaccgc ctgtggggcc
    18181 aggagccgaa gcccccggag ccatcgaaga caccagagcc gccccagacg ccgcggaccc
    18241 cgaggacgcc ccagacgctg gaggtcgcac cgcttccggg ctggtctcgc agcaaggagg
    18301 tcgagcggat gttgcgtgac cgcatcatca tgatcggcac gcccatcgac gacgcaatcg
    18361 ccaatgtcgt cgtcgcgcag ctcctcttcc tcgagagcga ggaccctgag gcgggcatct
    18421 cgctgtacct caactctccg gggggctccg tcaccgcgtc gctcgccatc cgcgacacct
    18481 tggaatacgt gaagccgccc gtatccacca tctgcatggg ccggtgccac ggcacggccg
    18541 cgttgctgct ggcctgcgga gcccggggcc agcgcatctc cctgccccag gggcgtatcg
    18601 gtatcgtgcc cctcgaggtg agagcgggca cggcggatga cccacagatc cgccataccc
    18661 tcgacaccat cgtccacctg ttcgccgagt gcaccggcca gacacgggag acggtgcgca
    18721 aggacctgac gcacgggcgc gagttctctc ccgagagcgc gatggcttac gggctcatcg
    18781 actcggtggt gaaccgctga acccgtgagc acgtcggatg tatcacctgg gggcccagcg
    18841 ctcccccgtc cgcccgcccg gctggctgat acgggagggc gtggccagcg cgaggcgcca
    18901 tccaaacctt gagtgaagcg tcttttgctc cccaccagga gagggcttga tggcttcgtc
    18961 aaaacaggga aacacccggc agttcgcggt cgtgaccggt gcctccagcg gcatcggcta
    19021 cgagctggcc agacagttcg ctcagaacgg cttcgacgtg ctgatcgccg ccgaggatga
    19081 cagcatcacg gaggccgcgc ggagcctcgc gaacggcgca cacatcgaga gcctgaaggt
    19141 cgacctcgcg acctatgacg gggtcgagca gctctacgcg aagatccagt cgctcggccg
    19201 gcccgtggat gccatcgcca tcaacgcggg cgttggcgtg ggcggagagt tcaccgagac
    19261 gaagctggag gacgagctca acctcatcca gctgaacgtc acctcggcgg tccacctggc
    19321 caagcgggtg gcccgggaca tggtgaagcg cggcagcggc aggatcctct tcacctcgtc
    19381 cgtcgcggcg atcatgcccg cgcccttcga ggcggtgtac ggcgcgtcca aggccttcct
    19441 gctgtcattc tcggaagcgc tgcgcaacga gctcgccgat gcgggcgtca gcgtcaccgc
    19501 gctcctgccg ggccccacgg agacgaactt cttccaccgc gcggggatgg atgacacccg
    19561 ggttggccag cagaagaagg acgatccggc ccaggtcgcg cgccagggct tcaaggcgat
    19621 gatggccggc gagcagaagg tcttcgccgg ctcggtcaag acccggctcc aggccgccgt
    19681 cgcccgggtg cttccggatc ccgccaaggt ccagatgcac cggctgatgt ccgagccggg
    19741 ctccgggtcc gatccagagc ccgagcacaa gtagtccggg gccagggggg ctccccatgg
    19801 caccagtcca cgcggtaggg tcggagcccc ttccagccct ccgcccgcca tgcgccccgc
    19861 cctgaccctt cccggcttcc tccgcgtcta cgcgttgcct gccctctggc tcttcgcgct
    19921 cccgctcttc ggcctgtggt tcgccagcca cgccacctcg cggttcgacc agaccgtcct
    19981 caccaccatc gagagccaga tctcccagga cgcctcgctc gacgaggcac ggcggcagga
    20041 gctgctggag ttcttccgca ccgttccggc ctcggcggcc tgcctctcga cggcggagga
    20101 gctggcgggg ttccgcgaca gcctcggtga ggcgtgctcg gacgtggagc agttcgatgg
    20161 gatccgcctc ctggcgctcg gctcggccct gctggggctc gcctccggaa tgattgccct
    20221 gctgtgcgcg ctggcggcgt tcatctcgcg gcccttccag tacggcagct tcgtggtggg
    20281 ctggaacgtg ctccgggtca ccggggcgct gcaggctctc gcccagggag ccctggccgt
    20341 gtggctgtcc tactgggtga ccgcggtgtg gttcgagcgc tactacccga agctcatcgg
    20401 catcatcggc ctgctggcgg ccttcgcgct cttccaggtg gtggccgcca tcttccgccg
    20461 ccccgccacg gacttcgagg tggaggcgga ggtgattgaa ccgacacacg cgccggagct
    20521 ctgggcccac gtgcgccagc tgtgcgagca gctgaagacc cagccgccgg atcacatcct
    20581 cgccggcatc gacaccaact tcttcgtcac cgagagcgag gtgcacgtcg ggc
//
