LOCUS       NZ_CP011509            10858 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Archangium gephyra strain DSM 2261 chromosome, complete genome.
ACCESSION   NZ_CP011509
VERSION     NZ_CP011509.1
KEYWORDS    RefSeq.
SOURCE      Archangium gephyra
  ORGANISM  Archangium gephyra
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Archangium.
REFERENCE   1  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Genome assembly of Archangium gephyra DSM 2261
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) Protein Science and Engineering, Institute
            of Microbial Technology, Sec-39 A, Chandigarh, Chandigarh 160036,
            India
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: HGAP Pipeline v. SMRT v2.3.0
            Coverage                          :: 79.3
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001027285.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:37:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,001
            CDSs (total)                      :: 9,898
            Genes (coding)                    :: 9,822
            CDSs (with protein)               :: 9,822
            Genes (RNA)                       :: 103
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 28 of 76
            Pseudo Genes (incomplete)         :: 45 of 76
            Pseudo Genes (internal stop)      :: 6 of 76
            Pseudo Genes (multiple problems)  :: 3 of 76
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6283310
            Orig. end                         :: 6294168
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10858
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="28"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10858
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10858
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5858](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5858)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            16..846
                     /gene="rsmI"
                     /locus_tag="AA314_RS24750"
                     /old_locus_tag="AA314_05055"
     CDS             16..846
                     /EC_number="2.1.1.198"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsmI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625294.1"
                     /locus_tag="AA314_RS24750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_05055"
                     /product="16S rRNA (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="WP_047857496.1"
                     /sec_met_domain="TP_methylase (E-value: 4.6e-29, bitscore:
                     101.0, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTLYLVATPIGNLGDISSRALETLRAVSFVACEDTRHSRVLLD
                     HFGISADTVSLPAFAEGQRAGRILERLEAGEDCALVTDAGSPGISDPGEKLVAEAIERG
                     VKVVPIPGPTALVAALSASGLPTGRFHFLGFLPRKGPERQAMLEEVAPLSATVGIYESP
                     RRLAETLLDLKEALGERRAVVARELTKVHEEFVRGTLSALAERYAAEEPRGEVVVLVEG
                     RTGERRWSEEELQRALEEGLGRGEKLKALSTELARRAGWSGQDVYRLGLGLKKR"
     gene            complement(937..2229)
                     /locus_tag="AA314_RS24755"
                     /old_locus_tag="AA314_05056"
     CDS             complement(937..2229)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553582.1"
                     /locus_tag="AA314_RS24755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_05056"
                     /product="hypothetical protein"
                     /protein_id="WP_047857497.1"
                     /transl_table=11
                     /translation="MSRLRAVVAALTLGVPFVATAADVTRVASSFEDEDPFGMFIDVGI
                     EHSQRRTKIVREALPTTAGATRQYQGELWYRSYDTRLNLDVAFGIAQDVELSFGLPIVL
                     LQDESWAFVSGTNPGNSTITNNFVRNNCGGSGAPCSLTSPEPLFNMPAQGFFETFRGGL
                     GNARFGFAWSIFNQRKDETKPTWTVGLDYEAPTAKLLDPSFVTSKEDRGPVGDRVHKYT
                     VSTALSRQIGLAEPYFRMHYTIPVRGPGAWTNCNNRNVDPQNLGHPQNCGAPGWERKET
                     GIQAPHVAGVMFGSEFQVLDTPTRKFKLDLRAMSNYVSEGRYYNELSGPLRKLLATGDY
                     IQIGGQFALTAQLSDFLSVRGSGMYLYNTDHVLTDEKIGRDVDGNGSVDITMNPSELNP
                     NFDYRTDFVSRRFLATESKDFRLDVSATLRF"
     misc_feature    2307..2321
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.26"
                     /tool="antismash"
     gene            complement(2371..3420)
                     /locus_tag="AA314_RS24760"
                     /old_locus_tag="AA314_05057"
     CDS             complement(2371..3420)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013376038.1"
                     /locus_tag="AA314_RS24760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_05057"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_245682586.1"
                     /transl_table=11
                     /translation="MVVSLLLGLSAGGVWWWKQRLASETPPATTEQQLTAPVAMGSGEA
                     GATAATPSATGPSAPPPSATAPSAAAPIAAAPSDPLTAAGLSRATIRIDGPMETAVTAA
                     AGPEVGPALAQVVTRTLVWWVDVPGDLRRGDTLDILYQVRPNEEPLVYAVRFTSNKTGQ
                     THRAYRFQPEGDKNPRYYLPSGEELELRLENSPLEDYEQVTSLLRDGRRHKGVDFKTPV
                     GTPVKAPFTGIVRRKNWSFRFNGNCIELEEIGGKHRRALFLHMDELPRSLKVGDRFNVG
                     TMLGRSGNSGRSFAPHLHYQLEAGDERVLDPYESHRTYRRSLAAGQRAAFDAEVRRQDG
                     LLGTTVAGG"
     gene            complement(3556..4974)
                     /locus_tag="AA314_RS24765"
                     /old_locus_tag="AA314_05058"
     CDS             complement(3556..4974)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940152.1"
                     /locus_tag="AA314_RS24765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_05058"
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="WP_047857499.1"
                     /transl_table=11
                     /translation="MAKILVIDDEANLRKVLAAMLRRDGFDVTVAADGEQGLAEFNKNG
                     ADIVVTDLVMPKAGGMEVLRAVNAANPDVPVIIITAHGTVDSAVEAIKAGAFDYVTKPF
                     DQAELSAVIAKAAKAHDVAQRSVRADAKARAAIIGESAQLQEVFKIIDKVADTPSTVLI
                     NGESGTGKELIASALHGASSRRDKPFIKINCAAIPHNLLESELFGYERGAFTGAVTSKP
                     GRFELADGGTLFLDEIGEIPVEMQVKLLRALQEGEFERVGGIKTTRVDVRLIAATNRDL
                     QAEIEAGRFRKDLYYRLAVVPIVLPPLRERRTDIPMLAGHFVEKYNRKLNKKIESISDD
                     AMALLQAYNWPGNIRELENLIERVLLFADGPSITAKDLPEPVRQGSGTPAPALSAAPLE
                     ASTGEGGLKDIVRMKAAELEKDLITKALEETGGNVTRAAKLLQISRKSLQTKMKEFGLR
                     DTTPPDGRDESIDE"
     gene            complement(5001..5858)
                     /locus_tag="AA314_RS24770"
                     /old_locus_tag="AA314_05059"
     CDS             complement(5001..5858)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002615877.1"
                     /locus_tag="AA314_RS24770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_05059"
                     /product="family 1 encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_047857500.1"
                     /sec_met_domain="Linocin_M18 (E-value: 3.1e-82, bitscore:
                     274.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDFLGHAENPLREDEWARLNETVIQVARRSLVGRRILDIYGPLG
                     AGVQTVPHDEYTGVSPGAVDIVGEQETASVFTDARKFKTIPIIYKDFLLHWRDIEAARL
                     HNMPLDVSAAAGAAALCAQQEDELIFYGDPKLGHEGLMNATGRLTVPLGDWATPGSGYL
                     AIVEATRRLNESGHYGPYAVVLSPRLFSMLHRIFEKTGVLEIETIRQLAADGVYQSNRL
                     RGDSGVVVSTGRENMDLAVAMDMVAAYLGASRMNHPFRVLESLILRIKHPDSICTLEST
                     PNRG"
     gene            complement(5886..6398)
                     /locus_tag="AA314_RS24775"
                     /old_locus_tag="AA314_05060"
     CDS             complement(5886..6398)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002615903.1"
                     /locus_tag="AA314_RS24775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_05060"
                     /product="ferritin"
                     /protein_id="WP_047862284.1"
                     /transl_table=11
                     /translation="MAGPPDNDLSTDVALVRQVLARELETINEYEAHARAASTPELRDF
                     FLHLAAEEKEHVAEAVHMLRLLDAGQEAHFAKPVTTGHFQGAIEGKPAPAPARAPASAP
                     AAAAPSPAAPSEPASRGPARGGRNANGQAEPPPGLVQPERVLYGVPAPPPSPGVQPLTV
                     GSLRRSR"
     gene            6560..8209
                     /gene="murJ"
                     /locus_tag="AA314_RS24780"
                     /old_locus_tag="AA314_05061"
     CDS             6560..8209
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="murJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940155.1"
                     /locus_tag="AA314_RS24780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_05061"
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="WP_276326928.1"
                     /transl_table=11
                     /translation="MSPGTRARGGGALFVAVGIFASRLMGLVRERFFAHYLGNGMAAAV
                     FKAALRIPNFLQNLFGEGVLSGSFIPVYAGLLGKGDTKEADRVAGAVFGLLALATSVMV
                     ALGMLATPLFVDTIAPGFEGEARSMAIQLVRILFPGTGMLVLSAWCLGVLNSHRKFLLS
                     YLAPVVWNLAIITTLVVAGLRGLPEERLVVVLSYGVVAGCLLQFAVQVPSVMRVLGGFR
                     PTLSTASESVRQVLRSFGTVVIGRGVVQVSAYVDTSYASLIADRALSTLTYAQTIYLIP
                     VSLFGMSISAAELPEMSRTAGAGEEVATKLRTRIEAGARRIAFFVVPSAAALLFIGDVV
                     AGGLLQTGRFTAADTRYLWYLLMGSAVGLVASALGRLYASAFYALKDTRTPLRFAVVRV
                     SLGAAAAWFLALRLPGLVGLPEHLGAVFLTVTSGMVAWFESQMLRRALMGQIGHVGVPR
                     ALLLKLWGAGLAAGLTGLGIKLALARALGTMPGVEAEWGGSLLAPPHLHPIILFLAVVL
                     PFGAVYFGVTGALGIPEARAVFQRILRRRAAR"
     gene            8536..10518
                     /locus_tag="AA314_RS24785"
                     /old_locus_tag="AA314_05062"
     CDS             8536..10518
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015349968.1"
                     /locus_tag="AA314_RS24785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_05062"
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="WP_245682894.1"
                     /transl_table=11
                     /translation="MLGIPAGRGGEREERGGRDRGSDRPRGEKGGEQREARPAKPEGEA
                     GAQPQQGAPREGAPREDRRPRGDRGGERGGRGGDRGGKGGGERRAQGPMVVVKRASGAV
                     ETRGPVTPAPSSTAPVEPAEASAPAETAAPAASVTPAPKAPPAPAPSAALYEEVPESQS
                     FAEMFEAQQKDGGVPGRRAVRIGEKVSGTIFQLGADTAFVTLSNAKSEAMIELRELKDD
                     EGVLRYGVGDTIEAHVIEAGARGILLSRALAKGSANMAMLAEARASGMPVEGMVLSVNK
                     GGVEVAIGDVRAFCPISQLDIRFVEKPDAFIGEKLTFRVTEVRDRNVVLSRRSLLEDEQ
                     RKLAAKTRETLAEGKVVKGKVTGVRDFGAFVDLGGVEGMIPVSEMSYMRVAHPSDVVKQ
                     GDEVEVEILRMEAAQPNSPDKAKQKERITLSMRARQEDPFKTALAELKEGDRLQGKVVR
                     LQPFGAFVELRPGVDGLVHISALSERRIAHPRDVVQVGESIWVQVEKIEPSDKRIGLRR
                     ITEEEAQRPAEERPAAAAAQQEKKPAEPAAPRPKVGQVVVGKVDRIEPYGVFLVFPGGK
                     GLIPASETGTERGTDLRKKFSLGQELKVALVDIDASGKIRLSITAAERAEERAEVEAWT
                     KSQQPVGGGKKGFGTFADLLKKSGK"
     tRNA            10638..10711
                     /anticodon=(pos:6293982..6293984,aa:Met,seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="AA314_RS24790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="AA314_R00058"
                     /product="tRNA-Met"
     gene            10638..10711
                     /locus_tag="AA314_RS24790"
                     /old_locus_tag="AA314_R00058"
     misc_feature    10792..10803
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.39"
                     /tool="antismash"
ORIGIN
        1 atgtgaggaa cggatatgtc ggggacgctc tatctggtgg ccacgcccat cgggaacctg
       61 ggggacatct cctcgcgcgc cctggagacg ctgcgcgcgg tgtccttcgt ggcctgcgag
      121 gacacgcggc actcacgcgt gctgttggac cacttcggta tctccgcgga cacggtgagc
      181 ctgccggcct tcgccgaggg ccagcgcgcc ggccgcatcc tggagcggct cgaggccggg
      241 gaggactgcg cgctggtgac ggacgcgggc agcccgggga tcagcgatcc cggggagaag
      301 ctggtggccg aggccatcga gcgcggggtg aaggtggtgc cgatcccggg ccccacggcg
      361 ctggtggcgg cgctgagcgc ctcggggctg cccaccgggc gcttccactt cctgggcttc
      421 ctgccgcgca agggaccgga gcgccaggcc atgctggagg aggtggcgcc gctctcggcc
      481 acggtgggga tctacgagtc cccgcgccgg ctggccgaga cgctgctgga tttgaaggag
      541 gccctgggag agcggcgcgc ggtggtggcg cgggagctga ccaaggtgca cgaggagttc
      601 gtgcgcggca cgctgtcggc gctcgcggag cgctacgcgg ccgaggagcc ccggggtgag
      661 gtggtggtgc tggtggaggg gcgcaccgga gagcggcgct ggtccgagga ggagctgcag
      721 cgggcgctgg aggaggggct cgggcgaggc gagaagctca aggcgctcag caccgagctg
      781 gcccggcgcg ccggttggtc cggacaggac gtgtaccggc tggggctcgg actcaagaag
      841 cggtgaagtc ccagggggac tcgaggggag ggtcaacccg ggagccgaga gaccctcacc
      901 ccgtccctct cccgagggga gaggggacat tgcctcctag aaccgcaggg tggcgctgac
      961 gtccaggcgg aagtccttgc tctcggtggc gaggaagcgc cgcgagacga agtccgtgcg
     1021 gtagtcgaag ttggggttca gctcgctcgg attcatcgtg atgtccaccg agccgttgcc
     1081 gtccacgtcc ctgccgatct tctcatcggt gagcacgtgg tccgtgttgt acaggtacat
     1141 gcccgagccc cggacggaca ggaagtcgga gagctgggcc gtcagggcga actgaccgcc
     1201 gatctggatg tagtccccgg tggcgagcag cttgcgcagc gggccgctca gctcgttgta
     1261 gtagcggccc tcggacacgt agttgctcat ggcgcgcagg tccagcttga acttgcgcgt
     1321 gggcgtgtcg agcacctgga actcggagcc gaacatcaca ccggccacgt gcggcgcctg
     1381 gatgcccgtc tccttgcgct cccaccccgg ggcgccgcag ttctgcgggt ggccgaggtt
     1441 ctgcggatcc acgttgcggt tgttgcagtt ggtccacgcg cccgggccgc gcacggggat
     1501 ggtgtagtgc atccggaagt acggctccgc caggccaatc tgccgcgaga gcgccgtgga
     1561 caccgtgtac ttgtgcaccc ggtcaccgac ggggccccgg tcctccttgg acgtcacgaa
     1621 gctcggatcc aacagcttcg ccgtgggcgc ctcgtagtcc agccccaccg tccacgtggg
     1681 cttcgtctcg tccttgcgct ggttgaagat ggaccacgcg aacccgaagc gcgcattgcc
     1741 caggccaccg cggaacgtct cgaagaaccc ctgcgcgggc atgttgaaga gcggctcggg
     1801 gctcgtgagc gagcagggcg cgcccgagcc cccgcagttg ttgcgcacga agttgttggt
     1861 gatggtggag ttgcccgggt tcgtgcccga cacgaacgcc caggactcat cctggaggag
     1921 cacgatgggc agcccgaacg acagctccac gtcctgggcg atgccgaacg ccacgtccag
     1981 gttcaagcgc gtgtcgtagc tcctgtacca gagctcgccc tggtactgac gcgtcgcgcc
     2041 cgcagtggtg ggcagggcct cgcggacgat cttcgtgcgc cgctgcgagt gctcgatgcc
     2101 cacatcgatg aacatcccga atggatcctc gtcctcgaag gacgaagcga cgcgggtgac
     2161 atccgccgcg gtggcgacga acggcactcc cagcgtcagc gcggcgacta cggcgcgaag
     2221 cctggacatc cgacctccgg aaccacttcc tcgggggtcg gggcgagggg tccgcttgga
     2281 ccacccgtgc cgcgtaaccc ccgggaaatg ttgagaaatt gtccggggac gctagccgcc
     2341 gcaagcaggg gtgtcaagaa agcgatggct tcagccgccg gctacggtgg tgccgagcag
     2401 gccatcctgc cggcgcacct cggcatcgaa ggccgcgcgc tggcccgccg cgagcgagcg
     2461 ccggtaggtg cggtggctct cgtacggatc cagcacgcgc tcgtcaccgg cctcgagctg
     2521 atagtgcagg tggggcgcga aggagcggcc gctgttgccg ctgcggccca gcatggtgcc
     2581 cacgttgaag cggtctccca ccttgagcga gcgcggcagc tcatccatgt gcaggaagag
     2641 cgcgcggcgg tgcttgccgc caatttcctc cagctcgatg cagttgccgt tgaagcggaa
     2701 gctccagttc ttgcggcgga cgatgcccgt gaagggcgcc ttcaccggag tgcccacggg
     2761 cgtcttgaag tccacgccct tgtgccggcg gccatcgcgc agcagcgacg tcacctgctc
     2821 gtagtcctcc aggggcgagt tctccaggcg cagctccagc tcctcgccgc tgggcaggta
     2881 gtagcggggg ttcttgtcgc cctcgggctg gaagcggtag gcgcggtgcg tctggcccgt
     2941 cttgttgctg gtgaagcgca ccgcgtacac gaggggctcc tcgttggggc gcacctggta
     3001 gaggatgtcg agcgtgtccc cccgccgcag gtcacccggc acgtccaccc accacacgag
     3061 cgtgcgcgtc accacctggg cgagcgcggg gcccacttcg gggccggcgg cggcggtgac
     3121 ggccgtctcc atgggcccat caatgcggat ggtggcgcgg gacagcccgg cggccgtgag
     3181 cggatccgag ggggcggccg cgatgggcgc ggcggcggaa ggggccgtcg ccgaaggagg
     3241 gggggcggaa gggccggtgg cggaaggagt ggcggcggtg gcgccggcct ccccggagcc
     3301 catggccacg ggcgcggtga gctgctgctc ggtcgtggcg ggaggcgtct ccgaggcgag
     3361 ccgttgcttc caccaccata cgcctccagc gctcagaccg agcagcaagg agacgaccat
     3421 caccggacct acagggcttt tcttcggctg tggtccgagg gtgggaagag gcggccgcat
     3481 tcaagctccc agagaggaaa ggggttgtgg ccgggaccga accgatggtt tcgcggcgat
     3541 atttcgccgt cccgatcact cgtcaatgga ttcatcccgc ccgtccggcg gggtggtgtc
     3601 gcgcaggccg aattccttca tcttcgtctg gagggacttg cggctgatct gcagcagctt
     3661 ggctgctcgc gtgacgttgc cgcccgtctc ctccagggcc ttggtgatga gatccttctc
     3721 cagctcggcc gccttcatgc ggacgatgtc cttgaggcct ccttcacccg tcgaggcctc
     3781 caggggagcg gccgagagag cgggcgctgg cgtgccggag ccctgacgga ccggctcggg
     3841 gagatccttc gcggtgatgg aggggccatc ggcgaagagc aacacgcgct cgatgaggtt
     3901 ctccagctca cggatgttgc cgggccagtt gtaggcctgc agcagcgcca tggcgtcgtc
     3961 ggagatgctc tcgatcttct tgttgagctt gcggttgtac ttctccacga agtgcccggc
     4021 gagcatcgga atgtccgtgc ggcgctcgcg caggggcggc agcacgatgg gcaccaccgc
     4081 cagccggtag tacagatcct tgcggaagcg tccggcctcg atctccgcct gcaggtcgcg
     4141 gttggtggcg gcgatgaggc gcacgtccac gcgcgtcgtc ttgatgccgc ccacgcgctc
     4201 gaactcgccc tcctgcagcg cgcgcagcag cttcacctgc atctcgacgg ggatctctcc
     4261 gatctcgtcg aggaagaggg tgccgccgtc ggccagctcg aagcggccgg gcttggaggt
     4321 gacggcgccg gtgaaggccc cgcgctcgta gccgaagagc tcggactcga ggaggttgtg
     4381 ggggatggcg gcgcagttga tcttgatgaa cggcttgtcg cggcggctgg aggccccgtg
     4441 caaggccgag gcgatgagct ccttgccggt gccgctctcg ccattgatga ggacggtgga
     4501 gggggtgtcc gccaccttgt cgatgatctt gaagacctct tgcagctgcg ccgactcgcc
     4561 gatgatggcg gcgcgggcct tggcgtcggc gcgcaccgag cgctgggcga cgtcgtgcgc
     4621 cttggcggcc ttggcgatga cggccgagag ctccgcctga tcgaagggct tggtgacgta
     4681 gtcgaaggcg ccggccttga tggcctcgac ggcggagtcc acggtgccgt gcgcggtgat
     4741 gatgatgacg ggcacgtcgg ggttggcggc gttgacggcg cgcaacacct ccatgccacc
     4801 ggccttgggc atgacgaggt ccgtcaccac gatgtccgcg ccattcttgt tgaactcggc
     4861 gagtccctgc tcgccatcgg ccgcgacggt gacgtcgaag ccgtcacggc gcagcatggc
     4921 ggcgagcacc ttgcggaggt tcgcctcgtc gtcgatgacc aggatcttcg ccatgggggg
     4981 ctggcggggg ctccgccgga ctagccgcgg ttcggcgtgg attccagggt gcagatggag
     5041 tcggggtgct tgatgcggag gatgagcgac tccagcaccc ggaagggatg gttcatccgc
     5101 gaggcgccca ggtaggcggc caccatgtcc atggccaccg ccaggtccat gttctcgcgg
     5161 ccggtggaga cgaccacgcc cgagtcgccg cgcagccggt tggactggta gacgccgtcg
     5221 gcggcgagct ggcggatggt ctcgatctcc agcacgcccg tcttctcgaa gatgcggtgc
     5281 agcatggaga agaggcgggg agagaggacg acggcgtagg ggccgtagtg gccggactcg
     5341 ttgaggcggc gcgtggcctc gacgatggcc aggtagccgc tgccaggcgt ggcccagtca
     5401 ccgagcggca cggtgaggcg gccggtggcg ttcatcagcc cctcgtggcc gagcttgggg
     5461 tccccgtaga agatgagctc gtcttcctgc tgggcgcaga gggccgcggc cccggcggcg
     5521 gcggacacgt ccaggggcat gttgtgcagg cgcgcggcct cgatgtcgcg ccagtgcagc
     5581 aggaagtcct tgtagatgat ggggatcgtc ttgaacttgc gcgcgtcggt gaagacggag
     5641 gccgtctcct gctcgccgac gatgtccacc gcgcccgggc tcacaccggt gtactcgtca
     5701 tgggggacgg tctgcacgcc ggcacccagc gggccgtaga tgtccaggat gcgacggccg
     5761 acgagcgaac ggcgggcgac ctggatgacg gtctcgttga ggcgggccca ctcgtcctcg
     5821 cgcaacgggt tctcggcatg tccaaggaag tcaggcatgg ggacgctcca gggggaggta
     5881 cggcgtcagc ggctgcgccg cagcgagccg acggtcaagg gttggacgcc cgggctgggc
     5941 ggcggggcgg gcacgccata caggacgcgc tcgggttgaa cgaggccagg aggcggctcg
     6001 gcctggccat tggcattgcg tccgccacgg gccgggcccc gggaagcggg ctcggacgga
     6061 gcggccggag acggcgccgc cgcggcgggc gcggaggccg gggcacgagc gggggcaggg
     6121 gcaggcttgc cctcgatggc gccctggaag tggcccgtgg tgacgggctt ggcgaagtgc
     6181 gcctcctgcc ccgcgtcgag gagacgcagc atgtggacgg cctcggccac gtgctccttc
     6241 tcctcggcgg ccaggtgcag gaagaagtcg cgcagctccg gggtggaggc agcgcgcgca
     6301 tgggcctcgt actcgttgat ggtctccagt tcgcgcgcca ggacctggcg gacgagcgcc
     6361 acatcggtcg aaaggtcgtt atctggggga ccggccatgg gagcgctgac catcgcggcc
     6421 cgcaggggaa ccgtcaagag aaaccatggc gcgggagttc gcgcttcaag caggtgaacg
     6481 ctccgcatag agtgcgtgcc ctcttgtgac cgttccccct ccaagctccg ctccctctcc
     6541 cgttcccgaa ccccgtcccg tgtcacccgg gacgcgagcc cgaggcggag gcgcgctgtt
     6601 cgtcgcggtg ggcatcttcg cctcgcggtt gatgggactg gtgcgcgagc gcttcttcgc
     6661 gcactacctg ggcaacggca tggccgccgc ggtgttcaag gccgccctgc gcatccccaa
     6721 cttcctgcag aacctcttcg gcgagggcgt gctctccggc tcgttcatcc ccgtgtacgc
     6781 gggcctgctg ggcaagggcg acacgaagga ggcggaccgg gtcgcgggcg cggtgttcgg
     6841 gctgctcgcg ctggccacca gcgtgatggt ggcgctgggc atgctcgcca cgccgctctt
     6901 cgtggacacc atcgccccgg gcttcgaggg cgaggcgcgg tccatggcca tccagctggt
     6961 ccgcatcctc ttcccgggca cgggcatgct ggtgctgtcc gcgtggtgcc tgggcgtgct
     7021 caacagccac cggaagttcc tcctgtcgta tctggccccg gtggtgtgga acctggccat
     7081 catcaccacg ctggtggtgg cgggcctgcg cgggctgccg gaagagcggc tggtggtggt
     7141 gctctcctat ggtgtggtgg cgggctgtct gttgcagttc gccgtgcagg tgccatcggt
     7201 gatgcgggtg ctcggcggct tccggcccac gctgtccacg gcgagcgagt ccgtgcgcca
     7261 ggtgctgcgc agcttcggca cggtggtcat cggccgtggc gtggtgcagg tgagcgccta
     7321 cgtggacacg tcctatgcgt cgctcatcgc ggaccgggcg ctgtccacgc tgacgtacgc
     7381 gcagaccatc tacctcatcc cggtgagcct cttcggcatg tccatctccg cggccgagct
     7441 gccggagatg tcgcgcacgg cgggggcggg ggaggaggtg gccacgaagc tgcgcacgcg
     7501 cattgaagcg ggcgcgcgcc gcatcgcctt cttcgtggtg ccctcggcgg cggcgctgct
     7561 cttcattgga gacgtggtgg cgggcgggct gctgcagacg ggccgcttca ccgccgcgga
     7621 cacgcgctac ctctggtacc tgctgatggg ctcggcggtg ggcctggtgg cctccgcgct
     7681 gggccggctg tacgcctcgg ccttctatgc gctgaaggac acccggacgc cgctgcgctt
     7741 cgcggtggtg cgcgtgagcc tgggggccgc ggcggcctgg ttcctggcgc tgcggctgcc
     7801 gggactggtg ggcctgccgg agcacctggg cgcggtgttc ctcacggtga cgagcggaat
     7861 ggtggcctgg ttcgagtcgc agatgctgcg gcgggcgctc atggggcaga tcggccacgt
     7921 gggggtcccc cgggcgttgc tgctcaaatt gtggggcgcc ggactggcgg cgggactcac
     7981 ggggctgggc atcaagctgg ccctggcccg ggcgctgggg accatgccgg gggtggaggc
     8041 ggagtggggg ggaagcctgc tcgctccacc ccacctacat ccgatcatcc tcttcctggc
     8101 ggtggtgctg cccttcgggg cggtctactt cggagtcacg ggcgccctgg gcatccccga
     8161 ggcgagggcc gtcttccagc gcatcctccg ccggagagcc gctcgctgac ccgggccgga
     8221 gccatggagg gcgggcgggc gagcccgatt ccagtggtgg gggatgggac aggcgacatg
     8281 tcgcgttatg gaggggttcc gggtgcgctt gacagaagat gaccacatgc gtcttccgtc
     8341 caagcacggc gcgtgtgtag agtgcgccgc cttttgaccc agcatggggg tacggtctcc
     8401 caaagctgga ttccgattac gttcaggaag gtcctggcag tgagcgacga gaagaacggt
     8461 tccgttggtt ctggtggcgg tggcggtcct gggggcttcg gccccaagaa gcccaaggcc
     8521 acctttggcg acgtgatgct cggcatcccg gcgggccgtg gcggcgagcg cgaggagcgc
     8581 ggcggccggg accgcgggtc ggatcgcccg cgcggcgaga agggtggcga gcagcgtgag
     8641 gcccgtccgg cgaagccgga gggcgaggcg ggtgcccagc cgcagcaggg tgctccgcgc
     8701 gagggcgcgc cgcgtgagga tcgccgtccg cggggtgacc gtggcggtga gcgcggtggc
     8761 cgtggcggcg accggggtgg caagggtggc ggcgagcgcc gtgcccaggg ccccatggtg
     8821 gtcgtcaagc gcgcctcggg tgcggtggag acgcggggcc cggtgacccc ggcgccgtcg
     8881 tcgaccgctc cggtcgagcc cgccgaggct tcggccccgg ccgagacggc cgctccggcg
     8941 gcgtccgtga ctccggcccc caaggctcct cccgcgccgg ctcccagcgc cgcgctgtac
     9001 gaggaggtcc ccgagtccca gtccttcgcc gagatgttcg aggcgcagca gaaggacggc
     9061 ggcgtcccgg gccggcgcgc ggtgcgcatc ggcgagaagg tgtcgggcac gatcttccag
     9121 ctcggcgcgg acacggcctt cgtgacgctg tccaacgcca agagcgaggc gatgatcgag
     9181 ctgcgcgagc tcaaggacga cgagggcgtg ctgcgctacg gcgtgggtga caccatcgag
     9241 gcgcacgtca tcgaggcggg cgcccggggc atcctgctca gccgcgcgct ggccaagggc
     9301 agcgccaaca tggccatgct cgccgaggcc cgcgcctccg gcatgcccgt ggagggcatg
     9361 gtcctctccg tcaacaaggg tggcgtcgag gtcgcgatcg gcgacgtgcg cgccttctgc
     9421 cccatcagcc agctggacat ccgcttcgtg gagaagccgg acgcgttcat cggcgagaag
     9481 ctcaccttcc gcgtcaccga ggtgcgcgac cgcaacgtgg tgctctcgcg ccgctcgctg
     9541 ctcgaggacg agcagcgcaa gctcgccgcc aagacgcgcg agacgctcgc cgagggcaag
     9601 gtggtcaagg gcaaggtcac cggcgtgcgt gacttcggcg ccttcgtgga cctgggcgga
     9661 gtcgagggca tgatccccgt ctccgagatg tcctacatgc gcgtggccca cccgagcgac
     9721 gtggtgaagc agggtgacga ggtcgaggtg gagatcctcc gcatggaggc cgcccagccc
     9781 aactcgcccg acaaggccaa gcagaaggag cggatcaccc tctccatgcg cgcccgccag
     9841 gaggatccct tcaagacggc gctcgcggag ctcaaggagg gcgaccggct gcagggcaag
     9901 gtggtgcggc tgcagccctt cggcgccttc gtggagctgc gtccgggcgt ggacggcctg
     9961 gtgcacatct ccgcgctgtc cgagcgccgc atcgcgcacc cgcgcgacgt ggtgcaggtg
    10021 ggcgagtcca tctgggtgca ggtggagaag atcgagccca gcgacaagcg catcggcctg
    10081 cgccggatca ccgaggagga ggcccagcgc cccgccgagg agcgtccggc cgccgccgcc
    10141 gcccagcagg agaagaagcc cgccgagccc gcggcgcctc gcccgaaggt gggccaggtg
    10201 gtggtgggca aggtggaccg catcgagccc tacggcgtgt tcctcgtgtt ccccggcggc
    10261 aagggtctca ttcccgcctc cgagacgggc accgagcgcg gcacggacct gcgcaagaag
    10321 ttctcgctcg gccaggagct gaaggtggcc ctcgtggaca tcgacgcctc cgggaagatc
    10381 cgcctctcca tcaccgccgc cgagcgggcc gaggagcgcg cggaggtcga ggcgtggacg
    10441 aagagccagc agcccgtggg cggcggcaag aagggattcg gcacgttcgc cgatctgttg
    10501 aagaagtcgg gcaagtaacg cccggcacgt tgtgcgcacg cgggaggcgc ggggaatgga
    10561 atacgcgcct cccgtcgttc gaggaaaaca gttgacggta cagggggagg gcggtactta
    10621 gcctcccgct tcgacgccgc ggggtggagc agcctggtag ctcgtcgggc tcataacccg
    10681 aaggtcgcag gttcaaatcc tgcccccgca actcagacaa gccggagacc ctgccggaaa
    10741 tagatgacag ggtctctggt gtttgacata gagcagcagc agtaaagcgc agcaaacggt
    10801 atcgcggggt ggagcagcct ggtagctcgt cgggctcata acccgaaggt cgcaggtt
//
