LOCUS       NZ_CP011509            25038 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Archangium gephyra strain DSM 2261 chromosome, complete genome.
ACCESSION   NZ_CP011509
VERSION     NZ_CP011509.1
KEYWORDS    RefSeq.
SOURCE      Archangium gephyra
  ORGANISM  Archangium gephyra
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Archangium.
REFERENCE   1  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Genome assembly of Archangium gephyra DSM 2261
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) Protein Science and Engineering, Institute
            of Microbial Technology, Sec-39 A, Chandigarh, Chandigarh 160036,
            India
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: HGAP Pipeline v. SMRT v2.3.0
            Coverage                          :: 79.3
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001027285.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:37:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,001
            CDSs (total)                      :: 9,898
            Genes (coding)                    :: 9,822
            CDSs (with protein)               :: 9,822
            Genes (RNA)                       :: 103
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 28 of 76
            Pseudo Genes (incomplete)         :: 45 of 76
            Pseudo Genes (internal stop)      :: 6 of 76
            Pseudo Genes (multiple problems)  :: 3 of 76
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6040053
            Orig. end                         :: 6065091
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25038
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="25"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..25038
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25038
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15038](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15038)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    433..446
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     gene            530..1426
                     /locus_tag="AA314_RS23825"
                     /old_locus_tag="AA314_04861"
     CDS             530..1426
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS23825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_04861"
                     /product="hypothetical protein"
                     /protein_id="WP_047857354.1"
                     /transl_table=11
                     /translation="MNSMSPRALALAALATSILAPSLAFAQKTTETLDPVWQRSNERAG
                     YTWWKTATDGTPNVTYYGDEKGAWTWDAPASSTWTRQDATSNVSWFYTVEGASTANSWF
                     RTTLPAKPGQRLAAFTLTSVDKPGQGIGINDGIYVFVDGKFSGTFASVSAKKASNGTVV
                     LDKVFPTGWRSDDLKTTVTSMAPGAHEIAIAFEEDFGWGGMTRPRIVAEYETVDVDGDG
                     VTDDKDTCPSSPAGSVVNASGCSIADLCLCEKDWKNHGEYVSCVTKISQDFIKAKLITK
                     EAGQGLISTAAKATCGK"
     gene            1643..2323
                     /gene="gntA"
                     /locus_tag="AA314_RS23830"
                     /old_locus_tag="AA314_04862"
     CDS             1643..2323
                     /codon_start=1
                     /gene="gntA"
                     /inference="COORDINATES: protein motif:HMM:NF041366.1"
                     /locus_tag="AA314_RS23830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04862"
                     /product="guanitoxin biosynthesis heme-dependent
                     pre-guanitoxin N-hydroxylase GntA"
                     /protein_id="WP_047857355.1"
                     /transl_table=11
                     /translation="MRTQVETTLRQWFEPKTYPCIPAVQSMTKHEYLVGIYDRFGEGTY
                     SRELARDLLFFRERQKQSRSLYLSFWAVFAPGEPLSEEEFETRMWRELSYLSSQEVPGT
                     PWDPLFSADPADPRFCFSLGGDAFFIVGVHPASSRLARRFPYPGIIFNLYDQFEELDRR
                     GQYTAIVKKNRERDMKFQGSINPMIEKYADRWESIQFSGRDNPPDWKCPFQHGLEPPGR
                     GSSS"
     gene            2320..2901
                     /locus_tag="AA314_RS23835"
                     /old_locus_tag="AA314_04863"
     CDS             2320..2901
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020905.4"
                     /locus_tag="AA314_RS23835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04863"
                     /product="urea carboxylase-associated family protein"
                     /protein_id="WP_047857356.1"
                     /transl_table=11
                     /translation="MIEIPAQTGVAFTLRPGQRLRVRDPEGLQVSDLFCFNRTDPGEWL
                     SSGRSVDYADTLLLTTGHALYSNRSRVMLRIVEDEVGRHDFLMTPCSLAMFRLVAGNEE
                     WHPSCHENLAKSLAPFGISPDQISTTFNIFMNVVFEPSGRLHIEPPLSRVGQSILFQAE
                     MELLVGLTACSHEETNAGRCKPITYELLDP"
     gene            3008..4489
                     /locus_tag="AA314_RS23840"
                     /old_locus_tag="AA314_04864"
     CDS             3008..4489
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037015.4"
                     /locus_tag="AA314_RS23840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04864"
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_053066641.1"
                     /transl_table=11
                     /translation="MPINPRRTLALSALLSISCGQASGQPPELASPELAVVDRLTVDND
                     LTPPEVSLTSPVEGAIVTGTVILQASATDDTSIARVEFYMGTQLIGSDTTAPYEAAWKT
                     WSGGNGPVVFSAKAFDTSGNMAESTPVNVTSATPGLASYDEALGAPACTPLETGCDSGG
                     LLWGTGPGAGELHPPNTLASSCPDLLPGGTQAAPSLDRLIVSTTSGTLQAGKRVRVQAI
                     VWAPLGGERLDLYSATEAASPSWVYLTTVSLASTGRHNLSASYVLPAGGPQALRGVLRS
                     GGGPASCNTTASSADHDDLVFAVGSEPDTTPPTVSLVAPTGGAVLRNNQVLTASAVDDY
                     DVARVELYAGSTLLGTLGASGQLGWNTRTVANGAYTLTAVAYDTAGLSSTSTPIQVTVD
                     NDYSPPIVSITSPTSGASFSDSVFVSVSASDDRQVQSVTFFLNGNSLGTDTVAPFETVF
                     STRKYPGGSYQLTALASDGTNFATSSPVQVWINTP"
     gene            complement(4518..4835)
                     /locus_tag="AA314_RS55055"
                     /old_locus_tag="AA314_04865"
     CDS             complement(4518..4835)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS55055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_04865"
                     /product="hypothetical protein"
                     /protein_id="WP_147333215.1"
                     /transl_table=11
                     /translation="MLKGVDGVIFVADSQRQCAEDNLSSLEEMERNLVDMGYDPVKLPR
                     VYSYNKRDLPDALPVEELEKQLNPQRKYPSFETIASQGVGVLASLKGVLRAILLDATQG
                     G"
     misc_feature    complement(5058..5072)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(5378..6811)
                     /locus_tag="AA314_RS50655"
                     /old_locus_tag="AA314_04866"
     CDS             complement(5378..6811)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025141.4"
                     /locus_tag="AA314_RS50655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04866"
                     /product="DUF4476 domain-containing protein"
                     /protein_id="WP_169800728.1"
                     /transl_table=11
                     /translation="MNLSSCLVLCLTLAALLPAPARAMDGALFQQLEARVDDEHLSDAK
                     LTLLKTAASTNTFTCAQVARLVERFSFGEDKLEALSTFKDRIEDPENKRKLVTLFSFDD
                     EKEKAKALLAHIQKAAPVAPSAAPAATDSASTSVSASSRGSSTGEMTPLLVNQVGAWPD
                     ADVRTLAAALQKEDFTDGKMNVLQTAISSRPEGFTSAQIQQLVPSLTLSDDMVRAVKMM
                     DEHILGMTSHEVRGVLGTYAFNDDKLKVLRVLKDAITDAENKFIILDEFTFGAHKEEAR
                     KILETIKPRSPVYGTIRSKRAIFVVDVSGSMEARFTTNRGESLTRLQFVQRELQAVLKE
                     QLPEDAKFNLVVFSTRVRTWKPRLVAATPQSVQEAVQYVGALQQGGGTNIHGALEKAFA
                     HTEVDAVYFLTDGMPTDGKKKAHAEILEDVAAWNARRKVVVNTVAFLMGSFHNDNKPRS
                     RELMLQLAKATGGVYRAIE"
     gene            6993..8033
                     /locus_tag="AA314_RS50660"
                     /old_locus_tag="AA314_04867"
     CDS             6993..8033
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002622035.1"
                     /locus_tag="AA314_RS50660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04867"
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="WP_075336169.1"
                     /transl_table=11
                     /translation="MPGPHDLFARFTFGQPERAAAELHAVLPTHVVSQVDWSTLRRESG
                     SVVDPELRETQSDLLFSARLRGGQPLLLYVLLEHQSSVDGWMALRMLRYVVRQLEHWRK
                     ANPDSEKLPVVVPLVMYHGPDGAWSAPRRVEELFDLPGKAEGQGEWRALVPRFEYLLDD
                     LTAERAEALMARPGPALVRLALLLLRYGRTEELPQRLPEWVALFAEVHAAPHGDEELGL
                     VVRYLLQVGDRTVRTAMGGVLRSVMETHRAEELMRTYGEELIEQGRLKGLEQGLEQGLE
                     QGLEQGRAQGRAESVLQLLTARGWLVSEQVRQRILTCTDMAMLERWFARALTTSSLSEV
                     LEELTQ"
     gene            complement(8045..9313)
                     /locus_tag="AA314_RS23860"
                     /old_locus_tag="AA314_04869"
     CDS             complement(8045..9313)
                     /EC_number="1.1.5.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625731.1"
                     /locus_tag="AA314_RS23860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04869"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_047857358.1"
                     /transl_table=11
                     /translation="MRTLSITLLLAALLSGCTSKPPNPDGPPQTPGDTEPPPEQPLPSG
                     PPVPTGPPNVPEFQPAFPGQTRVPAIQTKTALQVTELASGFRNPWAIAFLPDQRMLVTE
                     KPTGSLYIVTPQGAKSPAVAGLPPVDGRNQGGLLDVEVGPDYAQSGLIYWTYYEPRSGG
                     NGLAVARAKLVEGEKPRVEGVQVIFRMMPTLESTLHAGGRLVFTPDGKLFVTLGERSIL
                     EGRKQARDVRSHFGKVVRINPDGSVPLDNPFVSTGGAKPEIWSVGHRNILSAALDRQQR
                     LWTVEMGPRGGDELNRPEAGKDYGWPTIGYGEEYSGAPIHESPQGPGMEQPVYYWDPVI
                     SPSGMTIYTGELFPEWRDNVFIGGLSSQALVRLMMRNDRVVGEERLLTDLNARIREVVQ
                     GPEGALYLLTDETNGKLLKLTPR"
     gene            complement(9468..9614)
                     /locus_tag="AA314_RS55060"
                     /old_locus_tag="AA314_04870"
     CDS             complement(9468..9614)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS55060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_04870"
                     /product="hypothetical protein"
                     /protein_id="WP_156349883.1"
                     /transl_table=11
                     /translation="MRAGAEGPRRAADWSTLLVAKGKHTLTARATDTLGNVATSAAVSV
                     TVQ"
     gene            complement(9678..9836)
                     /locus_tag="AA314_RS55065"
                     /old_locus_tag="AA314_04871"
     CDS             complement(9678..9836)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS55065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_04871"
                     /product="hypothetical protein"
                     /protein_id="WP_116120983.1"
                     /transl_table=11
                     /translation="MDHGGGINGFVTHMMHLPKDDLTVMLLFNTEGPGSAHQLAEKLAR
                     LAVGIPR"
     gene            complement(10001..11536)
                     /locus_tag="AA314_RS58825"
     CDS             complement(10001..11536)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.4"
                     /locus_tag="AA314_RS58825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YcaO-like family protein"
                     /protein_id="WP_338021972.1"
                     /sec_met_domain="YcaO (E-value: 5.1e-26, bitscore: 91.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSQLQVLGHTPLARRVRSLLEDARWEAPLIIACEWSSVEELRQL
                     GQGSAPWVLVEEGRNGSVCVGPIFGPSGPACFSCYLRRRISNGATECRPCADEAAAERI
                     ATTLRAIWEEGVGGGQFQWELEAEGSRQRHLLLPIPPCTACAQRPLPRVRWTEFISSRL
                     GLVHKVILQPSPEPGICVAIAQGCRTSDFHTVHACNDGVAADVDPERARQRAVMESLER
                     YCAAFAPPATPLTRATSLQGVWMDPTPWLDSPQREPLARWTRAHCLSDGAPAWVPLALC
                     CIPYREPRDEATPSRQNSNGLALGSTPTEVAEHGMAELVERAAFLSAWRAGHEPVALEA
                     PLPIPGLHLSLISPAHERRAVVAAFLERPEPPYTALGLAARESLDAAMLVASLEAVQVH
                     WWLKRWVDLRPAPPQEMPRTLVELARFHAMRPEFRASREPWLRKQQGMAIDPGKRRAGK
                     QPPETAFVVDLTTRDVASAGLSAGRVLAPALAWVETRLAVDWASPEGVPPPLG"
     gene            complement(11546..13120)
                     /locus_tag="AA314_RS23870"
                     /old_locus_tag="AA314_04872"
     CDS             complement(11546..13120)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="AA314_RS23870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04872"
                     /product="radical SAM protein"
                     /protein_id="WP_047857360.1"
                     /sec_met_domain="PTHR43273 (E-value: 5e-61, bitscore:
                     205.9, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-11, bitscore: 44.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.1e-10, bitscore:
                     37.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFANSEFLPWSRYEAARERFTGFARHSPNARLWETLLARAGKTFG
                     LEANRVVSPTWRFLRDRPTVERLFNSASGGFQLQVQGNHLRISQVQPADELVAYVAECP
                     DEEQQALEVLFRRALDPLDALATWPAECFFSEQELQLLGRMSRSDTPPDAPAFGWMPGQ
                     DINYGGYVCVIAKLTRLCNLRCVYCHDWAEGPNQTMRFEVLAHLFQRTFTPAEHAVVDL
                     VWHGGEPTLLRPVGILRVLALQRWFRRPGQRIKNILQTNATTLNQDWVELFHHYRFQIS
                     VSLDGPASVHDRTRPQVGGRSSFPAVQRGLRLLRGAGLLKGVLMVVTPALVELGPQGLV
                     DFLQAEEVSEVGLLPMRPDNVSPPSPGTYLDQATYVRFLLGVREVLRQSPSRALRVREL
                     EAANRALAGQQSGFCELSGNCVGHFFLAELDGSIAHCDKYIGDPAYTLGNVLQHDFSEI
                     RSNPKTRALWAENQRATALMNTCPHFRYCRGWCPHERYVSQRHEPHASTSCCGLAPLFD
                     ALSNPSP"
     misc_feature    13103..13117
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.79"
                     /tool="antismash"
     gene            complement(13128..15038)
                     /locus_tag="AA314_RS23875"
                     /old_locus_tag="AA314_04873"
     CDS             complement(13128..15038)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03975"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03975.1"
                     /locus_tag="AA314_RS23875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04873"
                     /product="RiPP maturation radical SAM C-methyltransferase"
                     /protein_id="WP_211276524.1"
                     /sec_met_domain="TIGR03975 (E-value: 1.5e-193, bitscore:
                     643.7, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.5e-14, bitscore: 53.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMHSVSHPVVTGNAQAVATQAVPEVALVSMPFVSVVRPSIQLGL
                     LKTLAEQTGIKASTFHLNLEFACQIGTTLYERLCRHRGRMFGDWLFSVAAFGSQAPDLE
                     DRFLQDYEAEFQSLLADTGTTLERLKHLRHQEIPAYLDRMLALIPWERFRVVGFTCTFQ
                     QNAASFALARRLKERFPDLLCIFGGANFEGEMGLELVRSVDVVDYAVIGEADQAFPAFL
                     NALNRGEDPCQVPGVVARSHGTVTPLRPGPPFEQLDTLPVPDYEEFFARAESLGLLTPA
                     ARRDLLIPFESARGCWWGQKQHCTFCGLNGTTMAFRAKTPERVLKELGELAKRYRTFRF
                     EAVDNILAPSYLQKLFEPLVEAGRDYEFFYEVKSNLTRERIKTLRHGGVRRIQPGIESL
                     NTHVLKLMRKGVTGIQNVNTLRWALYYGIDVSWNLLWGFPHETKEDYEEQLRLMRLLIH
                     LQPPGGAGRIWMERYSPIFTDRKSFPALYVRPEASYTYVYPPSVQLEQVAYFFDYELHD
                     TLPPSVYEESGRHVTVWQNAWQGPERPTLTFWSSPDFLQIDDSRWPGERGTYTFQGPLA
                     SIYAACSDRPMSAEELKREFALDVSEEEFAQWLADFCACGLMMKDGHQYLSLALPATRN
                     R"
     misc_feature    complement(13161..13163)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15178..15564)
                     /locus_tag="AA314_RS23880"
                     /old_locus_tag="AA314_04874"
     CDS             complement(15178..15564)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS23880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_04874"
                     /product="hypothetical protein"
                     /protein_id="WP_147333213.1"
                     /transl_table=11
                     /translation="MSIKQTISPVEIEEMAKKLDKLGSQLSDNERALLVAVFGMASSAI
                     SDATKKVEEHLGAPVAGKLNKPDQFDLGKSETGKLPPLSQAFKESFSPGTAGRFALEGG
                     NQFKDSVDVSVGGICVSVSWSKDL"
     misc_feature    complement(15463..15465)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15920..15935)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.25"
                     /tool="antismash"
     gene            16042..17424
                     /locus_tag="AA314_RS50665"
                     /old_locus_tag="AA314_04875"
     CDS             16042..17424
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631788.1"
                     /locus_tag="AA314_RS50665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04875"
                     /product="hypothetical protein"
                     /protein_id="WP_075335960.1"
                     /transl_table=11
                     /translation="MEARGSTRVVAVTREEYQRAVAQLLQRHQVRGTPQEEAQGLLQAM
                     PEADLLAEVYGDRVLTLVPLTDKGSLVPEAEAALKEKYLRWCQPRGGGDCLGLFTDGPY
                     LRTDDRRTLALALAFGGVLDETRAALGRELSPQALLSSLVWAAGLYLALWLLPEPSTKA
                     VAAALSVVLLAWLGVDALWGLMDGWASMAHAAHEATTFEELRDAGEAFGKRIGTDAARA
                     LILGVATLTGRTLGEMATHLRSLPRFNQVQAQWAAQGMEGSVAVAMEEAAAVEVVVEQG
                     RALVVLTSPQAPAAINVLTRSGSSGVAGGHSGTVAIQHRGGNKQVILSNGERWHLPRGK
                     SYRDIPAEDRLGDELQAAVKEVAAKWSQAELSPDERTAIDRMLKAGKEYRANLLERQAR
                     GRWVEIQMQARFPGLSWNSRGVDITGPGGQSYHYELLSGTESNFALHGRRMASTFFRMI
                     FF"
     misc_feature    16507..16509
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17432..18043
                     /locus_tag="AA314_RS23890"
     CDS             17432..18043
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631787.1"
                     /locus_tag="AA314_RS23890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_047857362.1"
                     /transl_table=11
                     /translation="MTPNIHHEKRELIGERFELTKGPIYWLGPDLTLRDCTVVISAAGR
                     SLVPMSSQFINCTIQAKGLLKGVAWAPIKLKGCRFKGGFSGNDFGFRTDLFDREKAGGV
                     EDCDFSEARLHGCRFFNCDLRTIRLPLWPCFSFMDPLGHAAELVRREWPGQFGIVVEGL
                     AKNPSGTVAESWHAPTVAEKMDTTVEELRAALEGAPWVVM"
     gene            complement(18158..19009)
                     /locus_tag="AA314_RS23895"
                     /old_locus_tag="AA314_04878"
     CDS             complement(18158..19009)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (16-261). E-value:
                     8.1e-21. Score: 66.7. Matches aSDomain:
                     nrpspksdomains_AA314_RS23895_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.4"
                     /locus_tag="AA314_RS23895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04878"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_211276525.1"
                     /sec_met_domain="PF00561 (E-value: 1.5e-15, bitscore: 56.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 8.1e-13, bitscore:
                     48.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTRRGPVECASLGEGPAVLALHGAMGGHDQASLLARTAGVPGFR
                     YIAPSRPGYLGTSLSLGRTPKEQAELYRDLLDTLGIDRVALMAVSGGGPSALQFALSYP
                     KRCWGLVIISSVCSRIAKRPPLPWYLMKLAVHVSPLFALMKRKAERTPEEASRRSIPDP
                     VMRARTLNDPEAGPLLRELQLSTYDRLPLRIPGSDNDITLTHRELSFPLEQIKAPTLIV
                     HGTNDRMAPYAQAQRLAARVPGAELLSLEGGDHVGIFTHLHEVRARVGHFLGAHAPRAV
                     AS"
     aSDomain        complement(18227..18961)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AA314_RS23895_Abhydrolase_1.1"
                     /evalue="8.10E-21"
                     /label="AA314_RS23895_Abhydrolase_1.1"
                     /locus_tag="AA314_RS23895"
                     /protein_end="261"
                     /protein_start="16"
                     /score="66.7"
                     /tool="antismash"
                     /translation="PAVLALHGAMGGHDQASLLARTAGVPGFRYIAPSRPGYLGTSLSL
                     GRTPKEQAELYRDLLDTLGIDRVALMAVSGGGPSALQFALSYPKRCWGLVIISSVCSRI
                     AKRPPLPWYLMKLAVHVSPLFALMKRKAERTPEEASRRSIPDPVMRARTLNDPEAGPLL
                     RELQLSTYDRLPLRIPGSDNDITLTHRELSFPLEQIKAPTLIVHGTNDRMAPYAQAQRL
                     AARVPGAELLSLEGGDHVGIFTH"
     gene            complement(19171..20058)
                     /locus_tag="AA314_RS50670"
                     /old_locus_tag="AA314_04879"
     CDS             complement(19171..20058)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042696.2"
                     /locus_tag="AA314_RS50670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04879"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_053066646.1"
                     /transl_table=11
                     /translation="MSTPPRPPRTHRERPRDPGEHGPREPLEDDARSSLLSLPPPGLAG
                     QIDLCWATPGRASVGTSLHEFFPDAGAHLIFRHSEHGCRAVMIGPATERAAVEREAGAE
                     YLAIRFRPGQAPRLADVRASELTNGFVELTHLGGQPIQDVAEQLRLLPDLASRQRVLAE
                     LMRDVAPPLVGDVRCRRATQLLEAHRGQLRVETLAEELGLNVRGLERLFLQHFGMTPKR
                     MSRLVRLRHVLGALYSGRFTNLGALAVACGYSDQSHLIHDFKALTARLPGDKGALVNRR
                     LLSEETRVIHRYRR"
     gene            complement(20063..21820)
                     /locus_tag="AA314_RS23905"
                     /old_locus_tag="AA314_04881"
     CDS             complement(20063..21820)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="AA314_RS23905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_04881"
                     /product="AAA family ATPase"
                     /protein_id="WP_053066647.1"
                     /transl_table=11
                     /translation="MERKAAALVTYLAIEGPTQRSRLASLLWPDAPDRAARVNLRQLLR
                     RLRLTLGEDSLAGEDPVWLCEGLIVDALLFRKSFDAREYSKLTDFQGELLAGFSYDDCG
                     ELEEWLRLQRTRFHYLQCRAAEAEALRLEQAGQLEAALDTVRRLLQLQPTSEQAWQTAI
                     RLHLRLGDRSSALRAYRDCREQLHRELGIDASPETRALVQELERPSEQERPRARSSDEV
                     PLVMLSPPELVGRDTEWALLEEAWAAGRPVYVLGEAGIGKTRLVSEFCSAQGSWLLVAA
                     RPADPSTPYATSARVSRAVLGLEPERPLEPWVRQEIARLVPELEPSAPPLPSSPEEKAR
                     LAEALARLIRTRCGEMSALVLDDAHRADAASLELHLRVQDLLLEPEHGGDTLRMLTCFR
                     MGELSPAFEERLREHREAGLAAWLSLEPLMLASAGELLAQMGVPRLEAIVPQLAKYTGC
                     NPLFLIETVRSLVAAGFDGSFPAAPPPSDRVTWIVEQRLKRLSPDALRLARTVALAGAD
                     FSLELAACVLGLNPDQLAAPWKELEEAKVLRGATFTQGVLRRTVIETLPQPVREAVLRR
                     ISACLQQRR"
     misc_feature    21925..21938
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.71"
                     /tool="antismash"
     misc_feature    21980..21995
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     misc_feature    21991..22006
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            22246..23049
                     /locus_tag="AA314_RS23910"
                     /old_locus_tag="AA314_04882"
     CDS             22246..23049
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS23910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_04882"
                     /product="hypothetical protein"
                     /protein_id="WP_147333212.1"
                     /transl_table=11
                     /translation="MTAAPVKPVAPVPPPVRYPELVVTELRNEIAAHSSRIVRLLQDRA
                     ALDEQLEKIGRDEKSSTQLNEQRARLVRMVEDKNRELNEAVQRQETLLAMAAEHAEALE
                     ALGNERKLFRFMVGGGMGLRRLEDVQLGPAGSGASPGSALVGTEAPRVDVLGAVAFLPV
                     DFNSRDRHQTFSLGVMAGVGGNGFPANVYAGLTLKVWILYLNAGANFRKEDAWRHGPPT
                     QAAFWQGAWTPTLFAGLALDSEALLAIQRVLPPKRAPEGLQVDPR"
     misc_feature    23075..23090
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.29"
                     /tool="antismash"
     misc_feature    24925..24934
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 gacgggcccc cggcggatga ggctcgcgtt ccgccggggg cctgaaaacg gcgactccga
       61 tacggcgccg gcgccatttc ggacgtcagt tctggatcgg gatgcgcagc atcagcgcgc
      121 cgaccggagc cgtctccggg agacccttga agttcgcgtg gcacatcgcg cactggggct
      181 tgaagttgga gagcgggatg gagcggcgga agtaacctgc gcctcggacg gcagcacaac
      241 ctggccacgc tgctggagga agcgagcgag ctggggcgtg gcctgccccg gtacgtggag
      301 cgggacttcg cccggtacct ggaaaggcct ccgcgggctg acacactcct gacacgtcag
      361 gaacgcgtca gcgcgccgcg ttcacctgct cgaggccacg cgctctcctc tgagacacgc
      421 cggaccgtgc atggcacggg cattgctcct gtggctgacc gcttccacgg atgcagcgcc
      481 tccacgcggt cctctcctcc gagagccgcc acacttgaaa gaaatcccca tgaacagcat
      541 gtccccccgc gccctcgccc tcgcggcact cgctaccagc atcctggccc cgagcctggc
      601 gttcgcccag aagaccaccg agaccctcga cccggtgtgg cagcgctcca acgagcgcgc
      661 gggctacacc tggtggaaga ccgccacgga tggcaccccg aacgtcacct actacggcga
      721 cgagaagggc gcctggacgt gggatgcgcc ggcttcctcg acgtggacgc gccaggacgc
      781 gacgtcgaac gtctcgtggt tctacacggt ggagggcgcc agcacggcca actcctggtt
      841 ccgcaccacg ctgcccgcca agcccggcca gaggctcgcg gccttcaccc tcacctcggt
      901 ggacaagccg ggccagggca tcggcatcaa cgacggcatc tacgtcttcg tggatgggaa
      961 gttcagcggc acgttcgcct cggtgtccgc gaagaaagcc tcgaacggca ccgtggtcct
     1021 ggacaaagtc ttccccaccg ggtggcgcag tgacgacctg aagaccaccg tcacctccat
     1081 ggcacccggc gcccatgaga tcgcgatcgc cttcgaggag gacttcggct ggggcggcat
     1141 gacccggccg cgcatcgtcg ccgagtacga gaccgtcgat gtggacggtg acggcgtgac
     1201 ggatgacaag gacacctgcc cctcgtcgcc ggcgggctcg gtcgtcaacg cgtcgggttg
     1261 ctcgatcgcc gacctgtgcc tgtgcgagaa ggactggaag aaccacggcg agtacgtctc
     1321 ctgcgtgacc aagatctctc aggacttcat caaggcgaag ctgatcacca aggaggcagg
     1381 gcagggcctg atcagcacgg cggcgaaggc cacctgcggc aagtagcgca gacgcttcgg
     1441 gccgaggggc cgcgccggga gcgtcgtggc tgtcgtcttc ccaccactcg tctccggccc
     1501 gcggcccgag ttcctaggca ccctccaagc cgtccggtac ggtcccaaga tgttacgagt
     1561 tgaagcctcg gcccacctgt atgagccgag tgacgaggga ctcatcccgt caggcccagg
     1621 cgcgcgtggg gagggcgagc ccttgcgcac ccaggtagag accacgctgc ggcagtggtt
     1681 cgagcccaag acctatccct gcatccccgc cgtgcagtcc atgacgaagc acgagtacct
     1741 cgtggggatc tacgaccggt tcggcgaggg cacctacagc cgggagctgg cgcgggatct
     1801 gctcttcttc cgcgagcggc agaagcagtc caggtccctc tacctgagct tctgggccgt
     1861 gttcgcgccg ggcgagccgc tgtccgagga ggaattcgag acgcgcatgt ggcgcgagct
     1921 gtcctatctc tcctcgcagg aggtgccggg cacgccctgg gatccgctct tcagcgcgga
     1981 ccccgcggat ccccgcttct gcttcagcct gggtggggat gcgttcttca tcgtgggcgt
     2041 gcacccggcg agctcgcggc tcgcgcgccg ctttccatat cccgggatca tcttcaacct
     2101 ctacgaccag ttcgaggagc tggatcgccg ggggcagtac accgccatcg tgaagaagaa
     2161 ccgcgagcgg gacatgaagt tccagggctc catcaatccc atgatcgaga agtacgcgga
     2221 ccgctgggag tccatccagt tctcgggccg agacaacccg ccggactgga agtgtccctt
     2281 ccagcatggc ctcgagccgc ccggccgggg ttcgtcgtca tgatcgagat tcccgcccag
     2341 accggcgtgg ccttcacgct ccgcccgggc cagcgcctgc gcgtgaggga tcccgaggga
     2401 ctccaggtct cggacctgtt ctgcttcaac cggacggacc cgggggagtg gttgtcctcg
     2461 ggacgctccg tcgactacgc ggacaccttg ctgctgacga cggggcacgc gctctactcg
     2521 aaccgcagcc gggtgatgct gcgcatcgtc gaggacgagg tgggccgcca tgacttcctg
     2581 atgacgccct gcagcctcgc catgttccgc ctcgtggcgg gcaacgagga gtggcacccg
     2641 agctgccacg agaacctcgc gaagagcctg gcgcccttcg gcatctcgcc cgatcagatc
     2701 tccaccacgt tcaacatctt catgaacgtc gtcttcgagc cctcgggacg cctgcacatc
     2761 gagcccccgc tgtcgcgcgt cggccagtcc atcctcttcc aggcggagat ggagctgctc
     2821 gtcgggctca ccgcctgctc ccacgaggag accaacgcgg ggcgctgcaa gcccatcacc
     2881 tacgagctgc tggatccctg agaatcaatc ggagagctcg aagggcgtgg ggacgccgcc
     2941 ggaagtgaat aagcgggtgg gcgggcagtc agttcattgc cttctccacc ccctccggaa
     3001 cgtcctcatg cccatcaatc ccagacgcac cctcgcactc agtgccttgc tgtccatcag
     3061 ctgtggtcag gcctccggac aaccgccgga actggcatcg ccggagctgg cggtggtgga
     3121 ccgcctcacc gtggacaacg acctcactcc gcccgaggtg tccctcacct cgcccgtgga
     3181 aggcgccatc gtgaccggca cggtgatcct ccaggcgagc gccacggacg acacgtccat
     3241 cgcccgggtg gagttctaca tgggcacgca gctcatcggc tcggacacca ccgcccccta
     3301 cgaggccgcc tggaagacct ggtccggcgg caacggaccc gtggtgttca gcgcgaaggc
     3361 cttcgacacc tcggggaaca tggccgagag cacgccggtg aatgtcacct ccgccacgcc
     3421 agggctggcc tcctatgatg aggcgctcgg ggctcccgcg tgcaccccgc tggagacggg
     3481 ctgtgactcg ggcgggctgc tgtggggcac gggcccgggc gctggggagc tccacccgcc
     3541 caacaccctg gcctcgagct gcccggacct ccttcccgga ggcacccagg ccgcgccctc
     3601 gctggaccgg ctgatcgtct ccaccacctc tggcaccttg caggccggca agcgggtgcg
     3661 cgtgcaggcc atcgtctggg cccccctggg cggcgagcgg ctggacctct attccgccac
     3721 ggaggccgcc tccccgagct gggtgtacct cacgaccgtg agcctcgcct ccaccggccg
     3781 gcacaacctc tccgccagct acgtgctgcc cgccggaggc ccgcaggcgt tgcgcggcgt
     3841 cctgcgctcc ggagggggcc cggcctcgtg caacaccacg gcctcgtccg cggaccacga
     3901 cgacctcgtc ttcgccgtgg gctccgagcc cgacaccacc ccgcccaccg tgagcctcgt
     3961 cgcgcccacc gggggcgcgg tgctccgcaa caaccaggtg ctcaccgcgt ccgccgtgga
     4021 cgactacgac gtggcccgcg tggagctcta cgccggttcc accctgctgg gcaccctggg
     4081 cgcctcgggg cagctcggct ggaacacgcg cacggtggcc aacggtgcgt acaccctcac
     4141 cgcggtggcg tatgacacgg cggggctgtc ctccacgtcc acccccatcc aggtgacggt
     4201 ggacaatgac tattcgcctc ccatcgtctc catcacctcg cccacttcgg gtgcgagctt
     4261 ctcggactcc gtcttcgtgt cggtctccgc gagcgatgac cgccaggtgc agagcgtcac
     4321 cttcttcctc aatggcaaca gcctgggcac cgataccgtg gcgccgttcg agaccgtctt
     4381 ctccacccgg aaatacccgg gcggcagcta ccagctcacc gcccttgcct ccgacggcac
     4441 gaacttcgcg acttccagcc ccgtgcaggt gtggatcaac acaccgtgaa tgcggccacc
     4501 gtgctgggga agaggtgcta accgccctgg gtggcgtcaa ggaggatggc cctgagcacc
     4561 cccttgagtg aggccaacac ccccactccc tgcgaggcga tggtctcgaa gctcgggtat
     4621 ttccgctggg gattgagctg cttctccagc tcctccacgg ggagcgcgtc gggaagatcc
     4681 cttttattgt aggagtagac acgagggagc ttcaccgggt cgtaccccat gtccaccagg
     4741 ttgcgctcca tctcctccag gctcgacagg ttgtcctcgg cgcactgcct ctgcgaatcg
     4801 gcgacgaaga tcaccccgtc aacacccttg agcatgaggc gcctcgtgtt ctccgaggcc
     4861 acgtgcacga ccaggacgaa caggtggata cggctcttga agccacgaat ctcccccaag
     4921 ccaggcggca cgaagtcgaa agagtccgtt cgacccacga gcgtggagtg tgtgtgccac
     4981 cactcacccc tttggggcgg gaacttgctg cgtacgtatt gataggaggt cttttggcct
     5041 gccaggtcag gtccgcaata gacgatcttg atattgagtt ctctcgcgga atagttgagg
     5101 aacatgggga ggacgggtgg gggtagggca cttccaggca gaccttcggg gtccatcctc
     5161 ccggaaacaa atcggggagc ccaggctcag gacgtgcttc tgcccgaaaa aggcacttcc
     5221 aactcctgtt cagtcatagg gagcggccct cctcggcgtc cgcgcaccag tcctcaccct
     5281 ccagaggctt cccagttgcc cgatgcgtga cgcgggcggc ggacaacacc cccgccagca
     5341 ccagcacgag cgtgcccgcg agcggcagga gcgcgtccta ctcgatggcg cggtagacgc
     5401 cgccggtggc cttggccaac tgcagcatca gctcgcgcga cctgggcttg ttgtcattgt
     5461 ggaagctgcc catcaggaag gcgacggtgt tcaccaccac cttccgccgg gcattccagg
     5521 cggccacgtc ctcgaggatc tccgcgtggg ccttcttctt tccatccgtc ggcatgccgt
     5581 cggtgaggaa gtagacggcg tccacctcgg tgtgagcgaa ggccttctcc agagcgccgt
     5641 ggatgttggt tccacccccc tgctgaagcg cgcccacgta ctgcaccgcc tcctgcaccg
     5701 actgtggcgt ggctgcgacg aggcgaggct tccacgtccg cacccgcgtg gagaagacga
     5761 cgaggttgaa cttcgcgtcc tccgggagct gctccttcag cacggcctgc agctcgcgct
     5821 gcacgaactg gagccgggtg agcgactcgc cccggttggt ggtgaaacgc gcctccatgc
     5881 tgccggagac gtccaccacg aagatggcgc gcttgctgcg gatggtgccg tacaccgggc
     5941 tgcgcggctt gatggtctcc aggatcttcc gcgcctcctc cttgtgggcc ccgaaggtga
     6001 actcgtcgag gatgatgaac ttgttctccg cgtcggtgat ggcgtccttg agcacgcgca
     6061 gcaccttcag cttgtcatcg ttgaaggcgt acgttcccag caccccacgc acctcgtgcg
     6121 acgtcatgcc gaggatgtgc tcgtccatca tcttcaccgc ccgcaccatg tcgtcgctga
     6181 gggtgaggct cgggacgagc tgctggatct gcgcggaggt gaagccctcg gggcggctgg
     6241 agatggctgt ctggagcacg ttcatcttgc cgtcggtgaa gtcctccttc tggagcgccg
     6301 cggcgagcgt gcggacgtcc gcgtccggcc atgcgcccac ctggttcacc agcagcggcg
     6361 tcatctcgcc cgtgctgctg ccccggctgg acgcgctgac gctggtggac gcgctgtcgg
     6421 tggccgctgg cgcggcgctg ggggcaacgg gcgcggcctt ctggatgtgg gccaggagtg
     6481 ccttggcctt ctccttctcg tcgtcgaagc tgaagagggt gacgagcttg cgcttgttct
     6541 ccggatcctc gatgcgatcc ttgaacgtcg agagcgcctc gagcttgtct tcgccgaagg
     6601 agaaccgctc gaccaggcgc gccacttgcg cgcaggtgaa ggtgttggtg gaggccgcgg
     6661 tcttcaggag ggtgagcttc gcgtcggaga ggtgctcgtc gtccacgcga gcttcgagct
     6721 gctgaaagag cgcaccgtcc atggcccgag cgggcgcggg cagcaatgcg gcgagcgtga
     6781 gacagaggac cagacaactg gaaaggttca tgtctgaatg gtgaaggaag caggggggcg
     6841 cggcaatgcc ccggccggtc gagcgccgcg ccccactccg aggcgggcgt ctctttggtg
     6901 agagggtagt cgccggaacg gacgcctctg gacaggcgct gccctgcgcg gcgccgctgg
     6961 cccgccgcgt gctttccctg gcgctgctcg ccatgccagg ccctcatgat ctcttcgccc
     7021 gcttcacctt tggccagccc gagcgggccg cggccgagct gcatgccgtg ctgcccacgc
     7081 atgtcgtctc ccaggtggac tggtccaccc tgcggcggga gtccggctcc gtggtggatc
     7141 cggagctgcg ggagacccag agtgacctgc tcttctcggc ccgcctgcgc ggtggacaac
     7201 cgctgttgct ctacgtgctg ctggagcacc agtcctcggt ggacgggtgg atggcgctgc
     7261 gcatgctgcg ctatgtggtg cgccagctcg aacactggcg caaggcgaac ccggacagcg
     7321 agaagctgcc ggtggtggtg cccctcgtca tgtaccacgg gccggatggg gcctggtcgg
     7381 cacctcgccg ggtggaagag ctcttcgacc tgccgggaaa ggcagagggg caaggggagt
     7441 ggcgcgcgct ggtgccgcgc ttcgagtact tgctggatga cctgacggcc gagcgggccg
     7501 aggcgctgat ggcacgcccc ggcccggccc tggtccggct ggccttgctc ttgctgcgct
     7561 acgggcgtac cgaggagctt ccccagaggc tgccggagtg ggtggccctc ttcgcggagg
     7621 tccacgccgc ccctcatgga gacgaggagc tgggcctggt cgtccgttac ctcctccagg
     7681 tcggggacag gacagtccgc acggcgatgg gcggagtgct acgttccgtc atggagacac
     7741 accgagcgga ggagctgatg cggacctatg gcgaggaact catcgagcaa gggcgcctga
     7801 aggggctgga gcaggggttg gagcaggggc tagagcaggg cctggagcag gggcgggccc
     7861 agggacgggc ggagagtgtg cttcagcttc tcaccgcgcg gggctggctc gtcagcgaac
     7921 aggtccggca gcgcatcctg acctgcacgg acatggccat gctcgagcgc tggttcgctc
     7981 gcgccctgac aacctccagc ctctccgaag tgttggaaga gctgacgcag taatcgaggg
     8041 cggttcagcg tggggtgagc ttgagcagct tgccgttggt ctcgtcggtg agcaggtaga
     8101 gcgctccctc ggggccctgc accacctcgc ggatgcgcgc gttcaagtcc gtgagcagcc
     8161 gctcctcgcc caccacgcgg tcattcctca tcatcagccg caccagcgcc tggctggaca
     8221 ggcctccaat gaagacgttg tcgcgccact cggggaagag ctccccggtg tagatggtca
     8281 tccccgaggg agagatcacc ggatcccagt agtacacggg ctgctccatg cccgggccct
     8341 gcgggctctc gtggatgggc gcgcccgagt actcctcgcc atagccgatg gtgggccagc
     8401 cgtagtcctt gcccgcctcg gggcggttga gctcgtctcc cccgcgaggt cccatctcca
     8461 ccgtccacag ccgctgctgg cggtcgagcg ccgccgacag gatgttgcgg tgacccaccg
     8521 accagatctc cggcttcgcg cccccggtgc tcacgaacgg gttgtccagg ggcaccgagc
     8581 cgtcggggtt gatgcggacg accttgccaa agtggctccg cacatcgcgt gcctgcttcc
     8641 ggccctcgag gatggagcgc tcgccgagcg tgacgaacag cttgccgtcg ggggtgaaca
     8701 ccagccgtcc tcccgcgtgc agggtcgact cgagcgtggg catcatgcgg aagatgacct
     8761 gcaccccctc cacgcgcggc ttctctccct ccacgagctt cgcgcgtgcc accgccagac
     8821 cattgccgcc cgagcgcggc tcataatagg tccagtagat gaggccgctc tgggcgtagt
     8881 cgggacccac ctccacgtcg agcagacccc cctggttacg gccgtccacg ggcggcagac
     8941 ccgcgacggc gggagacttc gccccctggg gcgtgacgat gtagagcgag ccggtgggct
     9001 tctccgtcac cagcatgcgc tggtcgggga ggaaggcgat ggcccaggga ttcctgaagc
     9061 ccgaggcgag ctcggtgacc tgcaaggccg tcttcgtctg gatggccgga acgcgcgtct
     9121 gaccggggaa ggccggttgg aactcgggca cgttgggagg gcccgtcggg acgggggggc
     9181 cgctgggaag gggttgctcg ggcggcggct ccgtgtcccc gggggtttgc ggcgggccgt
     9241 ccgggttggg aggcttgctg gtacagcccg acagcagggc ggcgaggagg agggtgatcg
     9301 acaaggttcg catgggactc tctccaggac aggggcggga agggggtttc ccggcggtcc
     9361 aataaacaag gagggaagcg gcacgccaat caaacaatct ggcgggtgtc ggctggcgtg
     9421 ctgacgctgc tgagcagccc gacgtgggtg tcagacgccg tcttcggcta ttgcaccgtc
     9481 acggagaccg ccgcggaggt ggcgacattg ccgagcgtgt cggtggcccg ggccgtcagc
     9541 gtgtgcttgc ccttggctac gagcagtgtg ctccagtcag cggccctcct cggcccctcg
     9601 gctcctgccc tcacccaggg cccacttcgt cttctccctc gcgtaggtgc tctcgtagcg
     9661 gcgggcctcg tcggcgttca gcgggggatg cccaccgcca gccgcgcgag cttctcggcg
     9721 agctggtgcg ccgagccggg gccctccgtg ttgaagagca acatcacggt gaggtcgtcc
     9781 ttcggcaggt gcatcatgtg cgtcacgaac ccgttgatgc cgcccccgtg atccacggtg
     9841 ggtggtcctc gaggtcggcc atccccaggc taaagtcgta cgggtacgag gcgccctggc
     9901 cgtccgccgt ctccaccggc gtcggcatca ctcggcggct tcgcacagga cctgttcgtg
     9961 tagcgcgtgt cgggtgcgtc gagcacggag tgaagccgcc tcagcccagg ggaggtggca
    10021 ctccttccgg cgaagcccag tccactgcta ggcgtgtctc gacccaagcc agagccggag
    10081 ccagcacccg cccggcgctg agtccagccg aggcaacgtc ccgtgtggtc aggtccacca
    10141 cgaaggccgt ttccggcggt tgcttgccgg ctctcctctt gcccgggtct atcgccatgc
    10201 cttgctgctt ccgaagccac ggctcgcggc tggccctaaa ctcaggccgc atcgcgtgaa
    10261 accgtgcgag ctccaccagg gtgcgtggca tttcctgtgg aggggcgggt cggagatcga
    10321 cccagcgctt gagccaccaa tgcacctgca ctgcttcgag cgaggcgact agcatggcag
    10381 cgtcgagcga ctcccgcgcg gccaacccga gtgccgtata gggaggctcg ggcctttcca
    10441 ggaaggccgc caccaccgca cgccgctcat gcgctggtga gatcagactc aggtggagtc
    10501 caggaatggg cagcggcgcc tccagcgcca ccggctcgtg ccctgctcgc catgcggaga
    10561 ggaaggccgc cctctccacc aactccgcca tcccgtgctc cgccacctcc gtaggagtgc
    10621 tccccagggc taggccattg gagttctggc gggagggagt ggcctcatcc cgtggctctc
    10681 tataaggaat gcagcacagg gcgagcggta cccaggccgg tgctccatcc gagaggcagt
    10741 gggcgcgcgt ccaccgcgcc agcggttccc gctggggcga atccaaccag ggtgttggat
    10801 ccatccagac accctgcagc gaggtcgctc gggtgagggg cgtggcagga ggggcaaagg
    10861 cagcacagta tcgctcgagc gattccatca ccgctcgctg gcgggcccgc tcgggatcga
    10921 catccgccgc caccccgtcg ttgcatgcgt ggaccgtgtg aaagtctgag gtgcggcacc
    10981 cctgggcgat ggcgacgcag atgccgggtt ccggcgaggg ttggaggatt accttgtgaa
    11041 ccagtcccaa gcgcgaactg atgaactccg tccaccgcac gcgcggcagg ggccgctggg
    11101 cgcacgcggt gcagggggga atgggcaaga gcaggtggcg ctggcgcgag ccctccgcct
    11161 caagctccca ctgaaactgt cctccgccca cgccctcctc ccaaattgct cggagcgtgg
    11221 ttgcaatccg ctccgcagcc gcctcatccg cgcacggccg gcactcggtc gctccgttgg
    11281 agatgcggcg ccgcaggtaa cacgagaagc aggcgggacc gctgggtccg aagatcggtc
    11341 cgacgcaaac cgagccgttc cgcccctctt cgaccaacac ccagggagcg gagccctggc
    11401 ccagctgccg caactcctcc acgctcgacc actcacaagc aataatgagg ggcgcttccc
    11461 accttgcgtc ctccaagagg ctccgcacac ggcgagccag aggagtatgt ccaagcactt
    11521 gtagttggga actcacagtc agacctcaag gggaaggatt ggacagcgcg tcgaacaggg
    11581 gtgctaggcc acagcaactc gtgctggcat ggggctcgtg gcgttgcgag acataccgct
    11641 catgtgggca ccacccacgg cagtaacgga agtgggggca agtgttcatg agcgcggtgg
    11701 cacgctggtt ctctgcccag agggctcgtg tcttcgggtt ggatcggatc tcggaaaagt
    11761 cgtgctggag cacgttcccc aacgtgtagg cgggatcccc tatgtacttg tcacaatggg
    11821 cgatgctccc gtcgagctcc gcgaggaaga agtgacccac acaattgcca ctcagctcgc
    11881 agaatccaga ctgctgaccc gcgagcgctc ggttcgccgc ctccaactca cgcacgcgca
    11941 atgctcggct cggggattgg cggagcacct cgcgcactcc cagcaggaag cgcacatagg
    12001 tagcctggtc caggtaggtg ccgggggaag gcggggagac attgtctgga cgcatgggga
    12061 gcagccccac ctcggagacc tcctccgctt gaaggaagtc caccagcccc tggggcccca
    12121 gctccacgag ggcgggggtg accaccatga ggacgccctt gagcagcccg gcaccgcgca
    12181 gcaaccgcag cccgcgctgc accgccggaa agctggaccg cccacccacc tgtggccgtg
    12241 tccggtcgtg cacggaggcc gggccatcca ggctgacact gatctggaag cgatagtgat
    12301 ggaatagctc cacccagtcc tgattcagtg tcgtggcatt ggtctggagg atgttcttga
    12361 ttcgctggcc cgggcggcgg aaccaccgct gaagggcgag cacccgcagg atgcctaccg
    12421 gccgcagcag ggtgggctct cctccatgcc agacgaggtc caccaccgca tgctccgcgg
    12481 gggtgaacgt gcgttggaac agatgggcca gcacttcgaa gcgcatggtc tgattgggcc
    12541 cttccgccca atcgtggcag tagacgcaac ggagattgca aagccgggtg agcttggcga
    12601 tgacacaaac gtagccgccg taatttatgt cttgcccggg catccaacca aacgcgggtg
    12661 catccggggg cgtgtcgctc cgggacatcc tcccgagcaa ttgcaactcc tgctccgaga
    12721 agaagcactc ggcaggccag gtagccagcg catccagtgg gtccaacgcc cgccggaaga
    12781 gcacctccaa tgcctgctgc tcttcgtctg ggcactccgc cacgtaggcc accagttcgt
    12841 ccgcgggctg gacctgggag atgcgcagat gattgccctg cacctggagt tggaatcctc
    12901 ccgaggcgga gttgaagagg cgctcgaccg taggccggtc gcggagaaag cgccaagtgg
    12961 ggctcaccac ccgattcgcc tccagcccga aggtctttcc agcccgcgcc agcagtgtct
    13021 cccagagccg tgcgttgggg ctgtggcggg caaacccggt gaagcgctca cgagccgcct
    13081 catagcggct ccagggaagg aattcagaat tcgcgaacat gggcggctta ccggttccgg
    13141 gtagcgggca gggcaaggct taaatactgg tgaccgtcct tcatcatcag cccgcatgcg
    13201 cagaagtccg ccagccattg agcgaactct tcctcggaga catctagggc gaactcccgc
    13261 ttcagctcct cggcggacat gggcctgtcg ctgcaggccg cgtagatgga tgcgagcggt
    13321 ccctggaagg tataggtgcc ccgctccccg ggccagcgcg aatcgtcgat ctgcagaaag
    13381 tctggtgacg accagaacgt cagggtgggg cgctcaggcc cctgccaggc gttctgccac
    13441 accgtcacgt gccgcccgct ctcctcatag acagacggag gcagggtgtc gtgcagctcg
    13501 taatcgaaga agtatgccac ctgttccagc tggacggatg ggggatagac atacgtgtag
    13561 cttgcctctg gcctcacgta tagggctggg aagctcttgc ggtccgtgaa gatggggctg
    13621 taccgttcca tccagatacg gccggcacca cccggtggct gcaggtggat cagcagccgc
    13681 atcagtcgca gttgctcctc gtagtcctcc ttcgtctcat gcgggaagcc ccaaagcagg
    13741 ttccagctga cgtcgatgcc gtagtagagg gcccagcgca gggtgttaac gttctggatt
    13801 cccgtcacgc ccttgcgcat cagcttcagc acatgcgtat tcagcgactc gatgcctggc
    13861 tggatgcgcc gcactccccc atgccggagt gtcttgattc gctcccgggt gaggttggac
    13921 tttacttcgt agaagaactc gtaatcacgg cctgcctcga ccagaggctc gaacagcttt
    13981 tggaggtagc tgggggcgag gatgttgtcc acggcctcga agcggaaggt ccggtagcgc
    14041 ttagccaact cgccgagttc cttgagcact cgctccgggg tcttcgcgcg gaacgccatc
    14101 gtggtcccgt tcaggccaca gaaggtgcag tgctgcttct gtccccacca acagccccgt
    14161 gcgctctcga agggaatgag gagatcacgt cgagccgcgg gtgtcagtag cccgagcgac
    14221 tcggcgcgag caaagaattc ctcatagtcg ggcaccggaa gggtatcgag ctgttcgaag
    14281 ggcgggcctg ggcgcagcgg ggtcaccgtc ccgtgactcc gggcgaccac accgggcacc
    14341 tggcaggggt cctcgccccg gttgagcgcg ttcaggaacg ccgggaatgc ttggtctgct
    14401 tcgccgatga cggcgtaatc caccacatcg acggagcgga ccagttccag ccccatctct
    14461 ccctcgaagt tggcgccgcc gaagatgcag aggaggtccg ggaagcgctc cttcagccgg
    14521 cgggcgagcg cgaaggaggc cgcgttctgc tggaaggtgc aggtgaaacc gaccacccgg
    14581 aaccgctccc agggaatgag cgcgagcatt cggtccaggt acgcgggaat ttcctggtgc
    14641 cgcaggtgct tgaggcgctc gagggtcgtc cctgtatccg ctagcaggct ctggaactcg
    14701 gcttcatagt cttgcaggaa gcgatcctcc agatcgggcg cctgtgaacc aaaggcagcc
    14761 acagagaaga gccagtctcc gaacatgcgg cctcggtgac ggcacagtct ctcatacagg
    14821 gtggtgccaa tctgacaggc aaattccagg ttgagatgga aggtactggc cttgatcccc
    14881 gtctgctcag ctagcgtctt gagcaatccc agttggatgg aaggacgcac gaccgagaca
    14941 aacggcatgg acaccagtgc cacctcgggc accgcctgcg tcgcaacggc ttgggcgttg
    15001 cccgtcacta ccgggtggga cacactgtgc atatccatgg gaggacacct cgttctcgtg
    15061 gttacgtaca ccggcgctca gcctctagag ccgcggtacg gtgtgccgat ggggaaggca
    15121 tctgcgtgga agccgagccc accgcgatga cgctggtggg gcatttcgga gaggctgcta
    15181 gaggtccttg ctccaactca cggagacgca gatcccgccc acggagacgt cgacgctgtc
    15241 cttgaactgg ttgccccctt ccagggcgaa acggcccgcc gttcccgggg agaaggattc
    15301 cttgaacgcc tgggacagcg ggggaagctt gccggtctcc gacttgccca ggtcgaactg
    15361 atccggcttg ttgagctttc cggccactgg cgctccgaga tgctcctcca ccttcttggt
    15421 ggcgtcggag atcgcgctag aggccatgcc gaagacagcc actaacagcg cgcgctcgtt
    15481 gtcactgagc tgcgagccca gcttgtcgag cttcttggcc atttcttcga tttcaacggg
    15541 tgagatggtt tgtttgatgc tcatacatgg tcctatctga tgtgtcacca cgacacactt
    15601 cgctctcacg tgaggatggg ccaatcccgt ccaccaggaa gggtaaagtg atggtgacgc
    15661 gatggtttta ctccaacagg ctgacattcc cccttcccct cgcactggtc tgcctgcatt
    15721 ggagagaagc atgaggagca aagtatatct caaggtagac ctgtcacgtc tgaatgtgac
    15781 gtctagggtt agcgggggag caggatggcg tgaggcgggt gaatgcagac acgctgctca
    15841 tctggtgccg gtcgacgacg agacgcacac gctacccact aggcgggccc gcggactggt
    15901 aggaccactc acggggttct tggaaaaggc ctgaagccct gtcatgctga acgggcccac
    15961 tactcatcag tgggatccac ctgagcattg gttgagcgag ccagagcctg gagcaggcaa
    16021 tgcgaatctg agcctgccga ggtggaggcg cgcggtagca cgcgggtggt ggccgtcacg
    16081 cgagaggagt accagcgcgc ggttgcgcag ctgctccagc gccaccaggt gcgcggcacg
    16141 ccccaggagg aagcccaggg gctgctgcag gccatgcccg aggcggatct gcttgccgag
    16201 gtatacgggg acagggtgct cacgctggtg cccctcaccg acaagggctc gctcgtcccc
    16261 gaggccgagg cggctctcaa ggagaagtac ctccggtggt gtcagccacg gggcggcggt
    16321 gactgcctgg gcctcttcac ggacgggccc tacctgcgca cggacgacag gcgcaccctg
    16381 gctctggcgc tggccttcgg tggggtgttg gacgagacgc gagcggccct cgggcgcgag
    16441 ctcagcccgc aggcgctgct ctcctccctg gtgtgggctg cgggcctgta cctggcgctc
    16501 tggctgttac ctgagccaag cacgaaggca gtggcggccg cgctctccgt ggtgctgctg
    16561 gcctggttgg gcgtggatgc cctgtggggc ctcatggacg ggtgggccag catggcgcac
    16621 gcggcgcacg aggccaccac cttcgaggag ttgcgcgacg ccggcgaggc tttcggcaag
    16681 cgcataggta cggacgccgc ccgggccctc attctcgggg tggccaccct caccgggcgg
    16741 actctgggcg agatggcgac gcaccttcgc tcgctgccga ggttcaacca ggtgcaggcg
    16801 cagtgggcgg cccagggcat ggagggctcg gtggcggtgg ccatggagga agccgccgcg
    16861 gtggaggtgg tggtggagca gggccgggct ctcgtcgtcc tcacgtcccc gcaggcaccc
    16921 gccgccatca acgtcctgac gaggagcggc agctcgggag ttgctggagg gcactcgggc
    16981 accgtggcca tccagcaccg tggtggcaac aagcaggtca tcctcagcaa cggggagcgg
    17041 tggcacctcc cccgaggcaa gagctatagg gacattccgg cggaggacag gctgggcgac
    17101 gagttgcagg cggccgtaaa ggaggtggcg gcgaagtggt cgcaagctga gctgtcaccg
    17161 gacgagcgca ccgccatcga caggatgttg aaggcgggga aggagtaccg cgcgaacctt
    17221 ctcgagcgac aggcgcgggg gcggtgggtg gagatccaga tgcaggcgcg attcccaggc
    17281 ctgtcgtgga acagccgcgg tgtcgacatc accggcccgg gcggacagag ttaccattac
    17341 gagctcctgt ctggtacgga gtcgaacttc gcgctgcatg ggcgacggat ggcgagcacc
    17401 ttctttcgca tgatcttctt ctgaggcctg cgtgaccccc aacatccacc acgagaagcg
    17461 agagctcatc ggcgagcggt ttgagttgac gaaggggcca atttactggc tcggtcccga
    17521 cctgacactg cgtgactgca ccgtcgtgat cagcgcagcc gggcgctcgc tggtccccat
    17581 gtccagccaa ttcatcaact gcactattca ggcgaagggc ctgttgaagg gcgtggcgtg
    17641 ggcgccgatt aagctgaagg ggtgccggtt taagggcggc ttcagcggaa acgacttcgg
    17701 tttccgcacg gacctgttcg acagggagaa ggctggtggg gtcgaggact gcgacttctc
    17761 agaggcccgc ctccatggct gccggttctt caactgcgac ctgcgcacca ttcgactgcc
    17821 gctctggccg tgcttcagct tcatggaccc tctcgggcat gccgcagagt tggttcgccg
    17881 ggagtggccc gggcagttcg ggatcgtcgt tgagggactg gcgaagaatc cctcgggcac
    17941 ggtcgcagaa tcgtggcatg cacccacggt ggccgagaag atggacacga ctgtcgagga
    18001 gctgcgcgcg gccctcgagg gggcgccgtg ggtcgtcatg tagagccgta cccggccact
    18061 gcctataatg gccctggaaa ccgtattcga gcggttcacg aaggcgagct ggatgtctgg
    18121 gaattcgagc ctgcccgccg acccctccgc ccggcactca cgaggccacg gccctgggcg
    18181 cgtgtgcacc caggaaatgc ccgacccgcg cgcgcacctc gtgcaggtgc gtgaagatgc
    18241 ccacgtgatc gcccccttcg agcgagagca gttcggcgcc gggaacacgc gcggccagtc
    18301 gctgtgcctg ggcatacggg gccatgcggt cattcgtgcc gtgcacgatg agcgtcgggg
    18361 cctttatctg ctcgagggga aaagacagct cacggtgcgt gagggtgatg tcgttgtccg
    18421 acccgggtat ccgcagcggc agccggtcgt acgtgctcag ctggagctcg cgcagcaggg
    18481 ggccggcctc ggggtcgttc agcgtgcgcg cgcgcatgac ggggtccggg atggaccggc
    18541 gcgaggcctc ctctggagtc cgctcggcct tgcgcttcat caaggcgaag agcgggctga
    18601 cgtggacggc cagcttcatg aggtaccagg gcagcggtgg ccgcttcgcg atccggctgc
    18661 agaccgacga gatgatgacg agcccccagc agcgcttcgg gtagctgagc gcgaactgga
    18721 gcgcggaggg gccgcctccg gagacggcca tcagggccac ccggtcgatg ccgagcgtgt
    18781 cgagcaggtc gcgatagagc tccgcctgct ccttcggcgt ccggccgagc gagagggatg
    18841 tccccaggta gccagggcgc gagggcgcga tgtaccggaa gcccgggacg cccgcggtgc
    18901 gcgcgaggag cgatgcctga tcatggcccc ccatggcacc gtggagcgcg agcaccgccg
    18961 ggccctcgcc gagggaagcg cactcgacgg gtccgcgtcg tgtccgcacc actgccgggt
    19021 gcgaatcccc cgggaccgcc gccgcccccc gcggctcgag ttcatgtgaa gcacgcatgt
    19081 ctcttcctcc tgaagtcagc accagaggta ctgcttcctg gaggggctgt attgtagaaa
    19141 tccgacacgg cgcgcacggc cggcgggcgc ctaccggcga tagcggtgga tgacgcgcgt
    19201 ctcctcgctc aggagccgcc ggttgacgag tgcccccttg tcgccgggca ggcgagccgt
    19261 cagcgccttg aagtcgtgga tgaggtggga ctggtccgag tagccgcacg ccaccgcgag
    19321 cgcgccgagg ttcgtgaacc tgcccgagta cagcgccccg aggacgtggc gcaggcggac
    19381 gagccggctc atgcgcttgg gcgtcatgcc gaagtgctgc aggaagaggc gctccaggcc
    19441 acgcacgttg aggccgagct cctcggcgag cgtctcgacg cggagctgtc ctcggtgcgc
    19501 ctcgagcagc tgggtggccc ggcggcagcg cacgtccccg acgagcggcg gggccacgtc
    19561 ccgcatcaac tccgcgagca cccgctgcct cgaagccagg tccggcagga ggcgcaattg
    19621 ctcggccacg tcctggatgg gctgccctcc caggtgcgtc agttcgacga agccgttggt
    19681 gagctccgag gcacggacgt ccgcgaggcg cggcgcctgg ccgggccgga agcggatggc
    19741 gaggtactcg gccccggcct cgcgctccac ggccgcccgc tcggtcgcgg gtccgatcat
    19801 caccgcccgg cagccgtgtt cggagtggcg gaagatgagg tgggcgcccg cgtccgggaa
    19861 gaactcgtgg agcgaggtgc ccacgctggc gcggcccggt gtcgcccagc acaggtcgat
    19921 ctgccccgcg agcccggggg gaggaagcga gaggaggctc gagcgggcgt catcctcgag
    19981 gggctctcgc gggccgtgct cacccgggtc gcgcgggcgc tcgcggtgag tgcggggtgg
    20041 gcgcggtggc gtggacatac ggtcatcttc tctgttgcag gcaggcggag atgcgccgca
    20101 ggacggcctc gcgcaccggc tgcgggagcg tctcgatgac ggtccggcgc aacacgccct
    20161 gggtgaaggt agcgccgcga agcaccttcg cctcctccag ctccttccag ggcgcggcga
    20221 gctgatccgg gttcaacccc agcacgcacg cggccagctc caggctgaag tccgcgcccg
    20281 cgagcgccac ggtgcgcgcc agccggagcg catccggcga cagccgcttg agccgctgct
    20341 cgacgatcca cgtcacgcgg tcggacggtg gcggtgccgc gggaaagctt ccgtcgaagc
    20401 cggccgcgac caggctccgg accgtctcga tgaggaagag cggattgcag cccgtgtact
    20461 tcgccagctg cggaacgatc gcctccagcc ggggaacgcc catctgcgcc agcagctcgc
    20521 cagcggaggc cagcatcagc ggctcgagcg agagccacgc cgccagtccc gcctcccggt
    20581 gctcgcgcag ccgctcctcg aaggcggggg acagctcgcc catgcggaag caggtgagca
    20641 tgcgcagcgt gtcgcctccg tgctccggct ccagcagcag atcctgcacg cgcaggtgca
    20701 gctccaggct ggccgcatcc gcgcggtgcg cgtcgtcgag taccagcgcc gacatctccc
    20761 cgcagcgggt gcggatcaac cgggcgagcg cctcggcgag ccgcgccttc tcctcggggc
    20821 tggaaggcag gggtggggcg ctgggctcga gctccgggac gagccgggcg atctcctgcc
    20881 gcacccaggg ctccaggggc cgctccggct cgagccccag gacggcgcgg gacacccggg
    20941 cactcgtcgc gtagggggtg gagggatccg cgggccgggc cgcgacgagc agccaggagc
    21001 cctgggcgct gcagaactcg gagaccagcc gcgtcttgcc gatgcccgcc tcgccgagca
    21061 cgtagacggg gcggcccgcg gcccaggcct cctccaggag ggcccactcg gtgtctcgcc
    21121 cgaccagctc cggaggggag agcatcacga ggggcacctc gtcggaggaa cgggcccggg
    21181 ggcgctcctg ctccgagggc cgctcgagct cctggacgag cgcccgggtc tccggtgagg
    21241 catcgatgcc gagctcccgg tggagctgtt cccggcagtc gcggtaggcg cggagggcgg
    21301 aggaccggtc cccgagccgc agatggaggc ggatcgccgt ctgccaggcc tgctcggagg
    21361 tgggctggag ctggagcaga cgccgcaccg tgtcgagggc ggcctcgagc tggccggcct
    21421 gctccaggcg gagggcctcg gcctcggcgg cacggcattg caggtagtgg aaccgcgtgc
    21481 gttggagccg gagccactcc tccagctctc cacagtcgtc gtaggagaag ccggcgagca
    21541 gctcgccctg gaagtcggtg agcttggagt actcgcgggc gtcgaagctc ttgcggaaga
    21601 ggagggcatc gacgatgagg ccctcacaaa gccagacggg atcctctccc gcgaggctgt
    21661 cttcaccgag ggtgagccgc agcctgcgca ggagctggcg gaggttgacg cgtgcggccc
    21721 tgtcgggtgc atccggccac aggaggctgg cgagccggct gcgctgggtg gggccctcga
    21781 tggccaggta cgtcaccagc gccgctgcct tgcgctccat gtgtcttgct ccatgcaggg
    21841 gtgagttcac ccgggcacgg ccaagcactt cgatatgcgt ggcaaccgat ggcatacacc
    21901 ccccctccag aggagcgcag attcttcacg ctccgtgagg taggccgcaa ggatggtttg
    21961 agccccgtgc acgagcgaag acacgccgct gtcacgctgc agtcacgctt tggcgtgtgg
    22021 gtccagggcc tcgcatcacg cgccaatcac gccctcccgg cacagtgctc gtgaaggcgc
    22081 tggggtaggt cccgctcctt cccggtccgt gccgaaggct catgttcaag gggggagatg
    22141 atgttcgcga cacatggagg aaaacacgta gcgtggagag ccattcactg catcctgggg
    22201 gccgcgtgcc tctgggcggc gccggccctg gcgcagttca agcccgtgac cgccgcaccc
    22261 gtgaagcccg tggctccggt gccgcctccg gtccgctacc cggagttggt cgtcaccgag
    22321 ctgcgcaacg agattgccgc ccacagcagc cggatcgtgc ggttgctcca ggatcgcgcg
    22381 gccctggatg agcagctcga gaagatcggg cgggatgaaa agtcttccac gcaactgaac
    22441 gagcagcggg cgcggctcgt ccggatggtg gaggacaaga acagggagtt gaacgaggcc
    22501 gtccagcggc aggagacgct gctggccatg gccgcggagc atgcggaggc gctggaggcg
    22561 ctcgggaacg agcggaagct cttccgcttc atggtgggag gaggcatggg gctgcggcgc
    22621 ctcgaggacg tgcagctcgg gccggcgggc agtggggcgt ctccagggtc cgccctggtg
    22681 gggacggagg cgccccgggt ggatgtgttg ggagcggtcg cgttcctgcc cgtggacttc
    22741 aacagccggg atcgccacca gacgttcagc ctgggcgtca tggcgggagt ggggggcaat
    22801 ggctttccgg ccaacgtcta cgccggactg acgctcaagg tgtggattct gtacctcaac
    22861 gccggggcca acttccgcaa ggaggatgcg tggcgccacg ggccgccgac gcaggccgcg
    22921 ttctggcagg gagcgtggac gcccaccctc ttcgcggggc tggccctgga cagcgaggcg
    22981 ttgctcgcca tccagcgggt gttgccgccg aagcgggctc cggaggggtt gcaggttgat
    23041 ccgaggtgag gggcgggagg ggggcgcccc tcatctcggg tctttttcag ctcacggcag
    23101 cgccagggcg acgcgctggc gcaggcgcag gaagtcgtcg gacaggacgt agttgaggat
    23161 ctgctgcatg tcggcgcgct cgcgcagggc ctggagcagg ggctcggcgt tgtccaggcg
    23221 ggcggtggcg aagttcgggt cctcgcgcag caccatggtg aggcccaccg acacgtcgcc
    23281 gcacatcaac atgccggcgc ggtccgcgga gaacgccatg ccctccagca cgggctccag
    23341 ctccaccttg gactgggggc ccagctccag ggcggccggc tccagcgcct tgagcgcctt
    23401 gcgcgagtag gcccggcggt actgccgcac catctcctcg ttgttgcggc ccagggccgt
    23461 gaagagcggg gcgaagatgc ggatggagtt gccgaacagg tcctgcgtct cgccgcgcga
    23521 cagcttggag agcaccgccg tcttgttgag caggcccagc accgcgcggc cgaagaggaa
    23581 cttctgctcg cgggcgttga agcggcgcac cacgtcctgg cccacgcaca ggctcagcgg
    23641 ctcggtcgtc tccatgccga gcagcccgcg gcgggcctgg tacacctcga actcctccac
    23701 gccgaacacc tgcgccacgg cgcgcacggc cttgaagacg gcgtggtccg gcttgagctt
    23761 gtccgtcttg cggtccaccc cgagcagctc gaactgggcc gggtgcagct tgctgagctg
    23821 atcccccacg gcgcgcatga cctcgaggag cggcccgcgg gacgaggggt gcatgagccc
    23881 cgcgtccacg tccgccacgc tcaggcgctc ctgcgtctcg gtgggcaggc ggctgcgcat
    23941 ctccgagtag aaggtggcct ccgcctcgtt ggacgagcgc aggaagtgca gcacggccgc
    24001 ggcgcagaag gccttgtccg tctgccgggt gccttcccac aggcggaaga gcgcgtgcag
    24061 gctctccacg cgggtgggat ccagcttgag cagctgccgg ttctcctcga tggcgagctg
    24121 cgaggccgcc gcgtcgcgca tgtacagggt ggccagggcc gagcgggccg ggacgttggc
    24181 cggatccgcg tcgacgatgt gccggtacag ggtgatggcg cgcgtgggct cctccagcgg
    24241 gccggcgtac aggtccgcca ccttcagccg cagcgaggcc gcgcgcttca tgtccccggt
    24301 ggcctgggcc tgggcggcct gggcctccag catctgcgag agctccagca ggttgccggc
    24361 gcgctcgtag agcaccacca gccggtccac cagcgtgctg tcgcccgggg tgagctccag
    24421 cgcctgacgg tagagcgtgg aggcggaggc tccgtccccc agtccctgct cgtggagctg
    24481 cgccagcgtc acggtgtggc gcgcgcgctc ggccacgggg aggtccatct ccagcagccg
    24541 gcgcaggcag tccatcgcgc cctgccagtt gcgcacctgc tggaagaggg cggccatgcg
    24601 ctccagcacc tcggtgttgc gcggcaggcc ctcgcgcgcg gcgtgcaggt ggacggccgc
    24661 gcgggtcggc tcggacagct gatcctggta cagcgcgccc agcgtcaggt tcagcttcgc
    24721 caggtgggtt ggatcgcccc cgagcgggag gcgctgggtg agcagcgcgg cggcatcggc
    24781 gtaccggtgc tcctccagca gcagctgggc acgcagctcc agggcctcgg ggtgggcggg
    24841 ctggagggac agggtgcgct caagcagctc catcgcgcgg gcgcggttgc ccagcgagga
    24901 gaggtgcgtc ttggccgcgc cgaagaaggc ggccgcggcc gaggtgggat cctgctgggc
    24961 cagccgggcc tcggcgcgac gctcctgcag cgtggccagg tccgccgcgc ccccgcgcgc
    25021 ggccagcaga tcctccag
//
