LOCUS       NZ_CP011509            10843 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Archangium gephyra strain DSM 2261 chromosome, complete genome.
ACCESSION   NZ_CP011509
VERSION     NZ_CP011509.1
KEYWORDS    RefSeq.
SOURCE      Archangium gephyra
  ORGANISM  Archangium gephyra
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Archangium.
REFERENCE   1  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Genome assembly of Archangium gephyra DSM 2261
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) Protein Science and Engineering, Institute
            of Microbial Technology, Sec-39 A, Chandigarh, Chandigarh 160036,
            India
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: HGAP Pipeline v. SMRT v2.3.0
            Coverage                          :: 79.3
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001027285.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:37:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,001
            CDSs (total)                      :: 9,898
            Genes (coding)                    :: 9,822
            CDSs (with protein)               :: 9,822
            Genes (RNA)                       :: 103
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 28 of 76
            Pseudo Genes (incomplete)         :: 45 of 76
            Pseudo Genes (internal stop)      :: 6 of 76
            Pseudo Genes (multiple problems)  :: 3 of 76
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4767512
            Orig. end                         :: 4778355
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10843
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="20"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10843
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10843
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5843](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5843
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(309..1178)
                     /locus_tag="AA314_RS19170"
                     /old_locus_tag="AA314_03913"
     CDS             complement(309..1178)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002619967.1"
                     /locus_tag="AA314_RS19170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_03913"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_047856644.1"
                     /transl_table=11
                     /translation="MSLSDTERAHIQEALKNQRNALAVTRITGDPAEIGKGLVHLAELH
                     GMLEDHAESRRHYEEALGCFQTAGDKYGQAQALFGLGVVSANFEDHRHAIEHISGATAL
                     FNELKDQENEALCRAAIGESLRSLGHTKAAEEKYQEALLLYRQAKNGPRIAQLLLDIGD
                     IRMEAGEYEAARKRFSEALPLLEKEEDPEPLALCRLLLGEAEGLLGNHEAARPHLHTAA
                     ELYEQLHDHAYEARARWDLSIACTFVQDWKTARAELEAVIPLFEEQGRADDVAKARKVL
                     AHFDARGV"
     gene            complement(1188..2749)
                     /locus_tag="AA314_RS19175"
                     /old_locus_tag="AA314_03914"
                     /pseudo=""
     CDS             complement(1188..2749)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624015.1"
                     /locus_tag="AA314_RS19175"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_03914"
                     /product="short-chain fatty acyl-CoA regulator family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNENALNANVGLKLRSLRLARNIKQTDAAKDLGVSPAYLNLIEKG
                     KRVMPFPCCGRPCATSTRTPSSSCPRSARAGWTRRSRSCWTSRSSRASTSIRSPCRACR
                     PSRSWRARWRRSSTSTRTRARSWRTCWRSSMPRSGRARRRCRAARPGRACASTTRPSTR
                     "
     misc_feature    complement(2987..3000)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.83"
                     /tool="antismash"
     misc_feature    complement(2987..3003)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.26"
                     /tool="antismash"
     gene            3157..4575
                     /locus_tag="AA314_RS19180"
                     /old_locus_tag="AA314_03915"
     CDS             3157..4575
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013941510.1"
                     /locus_tag="AA314_RS19180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_03915"
                     /product="hypothetical protein"
                     /protein_id="WP_047856645.1"
                     /transl_table=11
                     /translation="MPPSRPGLSLVAWAALLGALCSCLPVRPPPSREEPGRLRYHVTYV
                     REPRHALEVGILRVGEGAPRDFLFSQPGGVERVRIFGADGSERELPVSAEGHVLVPPDT
                     RSLRYRYVLDASRRGRHAGFFTGQGEDDARQVAGRAWLLRPRSVGPALRAELVVEGVDA
                     LLPWVPDARGVYQLQGDDLVNSGFHSFGGRRCTVRLPGGVLEVAVLGRPSHMDDAALCA
                     WLERSAREVLTVRRSFPYPRVTVGLVTVPAREDPVPFGMVLWSTPPSISLWVGQDAAPA
                     AFTRDWVAVHELLHLAHPPIFPRVAWLSEGLATYYTELARARSGRQTPERAWVELLAGF
                     ERARRAVGSRTMEDVVTRGDSYLGTYWTGALVALHLDVELRRLTGNTRGLDDVLERLAE
                     SGPAATFDAFGAAVDAIAGRPLFHEVLSRHLPRPALAELEPLLEALGVEPAPDGVRLGI
                     ARDSTLRDALVAPR"
     misc_feature    4480..4482
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4664..4900
                     /locus_tag="AA314_RS19185"
                     /old_locus_tag="AA314_03916"
     CDS             4664..4900
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015350980.1"
                     /locus_tag="AA314_RS19185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_03916"
                     /product="hypothetical protein"
                     /protein_id="WP_053066536.1"
                     /transl_table=11
                     /translation="MNIKTMAAIVGTLSLGTLATGCATSKSAAPADQTGTAAASQEKGG
                     ESQCSGQKAGTTEEKGGEHKCGANGCGGATKPQ"
     misc_feature    complement(4665..4679)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.01"
                     /tool="antismash"
     gene            5001..5843
                     /locus_tag="AA314_RS19190"
                     /old_locus_tag="AA314_03917"
     CDS             5001..5843
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015350979.1"
                     /locus_tag="AA314_RS19190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_03917"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_047856647.1"
                     /sec_met_domain="DUF692 (E-value: 1.8e-101, bitscore:
                     338.0, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYARRHGLKPLGAGIGLRREFYARLPETSRALDWVEIIPENFLT
                     LGGRPQRALDACVERWPVLPHGVALNIGGPEPLDEDYLSGLKALVERVDAPFFSDHLCY
                     SRLRGAYLHDLLPLPFSEEAVEHVVPRVREVKERVGRPFLLENPSYYARMPGGTLDEAD
                     FLRHVAEEADCGLLLDVNNVYVNARNHGYDPRAFLDALPLERVVQIHLAGHEQQPDVII
                     DTHGAPVCDEVWSLYRYVLERTGPVSTLLEWDQDIPSLEAVLDEADRARAVLAEVEAR"
     gene            5840..6556
                     /locus_tag="AA314_RS19195"
                     /old_locus_tag="AA314_03918"
     CDS             5840..6556
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624019.1"
                     /locus_tag="AA314_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_03918"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_047856648.1"
                     /transl_table=11
                     /translation="MKPGLRGFFDSMEQYLTRPGPDALERLYTAHPGWDAPRSRVALYG
                     QMVRHHVTSTLEKLYPLTRAGVDAAPWAELVRAYEASSPSRSFEMNHLGEGFPGFLADE
                     AARRGLPDFLPALARFEWTDFAVYTSMEPVPERVERLTVNPTLAVLEHPFQLCAYVRRQ
                     GRGQPEAGQELALLWRHPERLVTMFLAANDRSLLAVKMAVEGLTPSQVAEATGVAEADI
                     RAVVESCVADGLVLSP"
     gene            complement(6633..8975)
                     /locus_tag="AA314_RS19200"
                     /old_locus_tag="AA314_03919"
     CDS             complement(6633..8975)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS19200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_03919"
                     /product="hypothetical protein"
                     /protein_id="WP_047856649.1"
                     /transl_table=11
                     /translation="MWKKTWLIGILMAATALSGCSCGPTPGGPDGGGSTDGGLNGPDGG
                     GTDGGGDDGPTIGSLVISPTKPLLTVTGSTSASQKFTVMGTYSDGHTEDVTSKATFSID
                     DTRLGLFLGSNFNSSTTVGGTSFVRARIGTKSVSTDITVKLDQKVSDTSGPSGSPVPPN
                     PDGRFGGAVDVALKPQIVYPNHGVMVPPNLGQLEIHFLSGPSTNTLFELQFSNTITDVR
                     VYLRCYLPSGFTPPTGAVPSGQRGCIYTPEDKVWKFLAESNRGGQPVRLIVRSTDDSGA
                     GKVGVSDPISIQFARAEIKGALYYWTTSGGTGVMRYDFAGTGTPSATPVLRAGNINTSV
                     SCVGCHALSRNGKKLVAEVNGQNDGRLALIDLSAFDSTTGKVDLAQSGTKLSNFESWNP
                     DGTKFVGTYADSGSSRYTLKLFNGDTAAYEGEITGTGTSTNPANHPDWSADGQKIAYMS
                     MGLAGTNQRSFKGAIKMVTAKTEGGWNEPVTVVSSLGGRNRYYPAIAPDSSFLVFNEST
                     CPSGESHTDCNGDTDPTAKLWAAKLEANATPVELANANKGGVMDKGQANLTNSYPKWSP
                     FVTRGNNGDTSRLMWVTFSSSRKYGLRQPVTASGENSWGTLLWMAAVDPDKVGTGDPSY
                     TAFALPFQDINTSNHIAQWASYFVSNGCRTDQESCSTGSTCCNGLQCVQKNQDPPIPCE
                     VDGACVCEAIPVCKLSFEACSTVAPCCEGLRCLDNTTGADCAGGSCTCTPPCSGFGQAC
                     GGASACCDGLLCVAGAGGRSTCQPDIR"
     gene            complement(9150..9911)
                     /locus_tag="AA314_RS19205"
                     /old_locus_tag="AA314_03920"
     CDS             complement(9150..9911)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS19205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_03920"
                     /product="hypothetical protein"
                     /protein_id="WP_053066537.1"
                     /transl_table=11
                     /translation="MRQTTYSVMMALALVASACGGFDNTPFRTGTVRGQLTEADPSVAL
                     VSLVGHPEVRGTVAADGSFVLERVPAGPGELFIVASADKAVRLPVVVPGGGSARLEDVV
                     PRAAGFLELRVRGTARQELEEGRASVLGTPFQQQPLAKDGSLRVGPLPEGCYTVEASAS
                     GFPVKKTEACVTESESKEVKIQLPGTEDDVDFVNRGCATTGCERGTQCASDGRCVECLS
                     NEQCAPGLACRDERCQTPLPPDTTERRPSPP"
ORIGIN
        1 cgcggaggcg ggcgagcagt ggatctcccg gctcctccgc gcgggctccc tgtgcagcgg
       61 aggcctcttc ctcgcctccg tggcgctgga gttcctgccc caatccgaga ccgtgcacgt
      121 ggccatcgac gtgctgcgca agggcgcggc ctcggccctg ctggtgacgc ccgtggtgcg
      181 gctggtggtg gccggcacca gcctgggtct ccggggcgag tggaagtacg cgctctacgc
      241 cgccggagtg ctgggactgc tcgcggtggc ggtgggcgcg ggactccacg cctgagtcac
      301 cgcccgggtc acaccccgcg cgcgtcgaag tgggccagca ccttccgggc cttggccacg
      361 tcgtcggcgc gtccctgctc ctcgaagagc ggaatcaccg cctcgagctc ggcgcgcgcg
      421 gtcttccagt cctgcacgaa ggtgcacgcg atgctcaggt cccaccgggc ccgcgcctcg
      481 taggcgtgat cgtgcagctg ctcgtacagc tccgccgccg tgtgcaggtg cggacgcgcc
      541 gcctcgtggt tgcccagcag gccctcggcc tcgcccagca gcagccggca cagcgccagg
      601 ggctccggat cctcttcctt ctccagcagg ggcagtgcct cggagaagcg cttgcgcgcc
      661 gcttcgtact cgcccgcttc catgcggatg tcgccgatgt ccagcagcag ctgggcgatg
      721 cgcggcccgt tcttcgcctg ccggtagagc agcagcgcct cctggtactt ctcctcggcc
      781 gccttggtat ggcccagcga gcgcagcgac tcgccgatgg ccgcccggca cagcgcctcg
      841 ttctcctgat ccttcagctc gttgaagagg gccgtggctc cggagatgtg ctcgatggcg
      901 tgccggtgat cctcgaagtt ggcgctcacc accccgaggc cgaagagcgc ctgcgcctgg
      961 ccgtacttgt ccccggccgt ctggaagcag cccagcgcct cctcgtagtg gcggcggctc
     1021 tcggcgtggt cctcgagcat gccgtgcagc tcggccaggt gcaccagccc cttgccgatc
     1081 tccgcggggt cgccggtgat gcgcgtcacg gcgagcgcgt tgcgctggtt cttcagggct
     1141 tcttggatgt gggcgcgttc ggtatcggag aggctcatgg tgggggctca gtgctcctcg
     1201 cccttgttgc gtcggcgcgg ctgcttgtcc agcgaatccg cacggccctc gccattgctt
     1261 cgcccggcct cgtgcaccag caggggcgag aagaagcaat ccttcttggt gtattcgtcg
     1321 aaggagaagg cgaagcggta gctggccgcc gcgcgctggt tgcagtcggt gcgctcgcag
     1381 aagcggcagg agatgccgct gggcaccgcg tccttgcgca gatccgtggt gggcagcccg
     1441 tacgccaggt acttggcgtt ctccgcgtgc gtgcccaggc caatcgagta ggccgtgccg
     1501 cgcacgatgg agccctcaat cggctgcaac tgcaccttgg cgaagcagaa gtacgaggtg
     1561 ccgtccggca tcatcgagta ctgccgggtg atttgagacg ggttgaggaa ggccaggtgc
     1621 acggcccact tgccgcacga gccgccgccc gtggcgaact tgatgccggt gccgctgtag
     1681 cgcttggaga tattgccggc gatgtccgag cgcaggaagt ggaagggcag gcccttgcgc
     1741 ttgggatccg acaggttgca caggcggtgg gccaccgtct cgtacgtggt gccgaagagg
     1801 ttggagagca gctccacgtc gtagcgcgtg cgctccacct ccttgaagaa gtccccgtac
     1861 ggcagcatca gcgcgccggc gaagtagttg gccaggttca ccttgatgag ccgctgcgtc
     1921 tccgcgtgcc gcgtgcgcac cgcgcccacg atccgctcca ccagcttctc cttgtccaac
     1981 accatgaggc cgatggacgc ggcgagctgg aacttgagcg gctgctcggt caggtccggc
     2041 gagaggatga gctcctgggt ctccggatcg aaccggcgca ccaccgagga gccgctggcc
     2101 gcggactcga agcgcacccg gtagccgaag cgctcctcca gcagtggcac cagctgctgg
     2161 ctggtgagca ggcgccccag cttgaagtca cgccgcagcg cctcggcctg ctcctccagc
     2221 tcggggaagt agttgtggtg cgtctggagg aagtcgctca cctcgtcgaa gggcgagtag
     2281 tcgaagcgca ggcccggccc ggacgagctg cccggcaccg tctgcgtgcg cgcccgctcc
     2341 tcggcattga gctgcgccag cacgttctcc agctgcgtgc gcgtgttctt gtagaggttg
     2401 aagagcgccg ccaccgtgcc cgccagcttc ggctcggccg acaggctctg cagggactcc
     2461 ggatcgatgt cgaggctctt gaggagcggc tcgtccaaca gcttcgcgag cgcctcgtcc
     2521 acccggccct cgccgagcgt ggacatgaac tgctcggggt cctggtcgaa gtagcgcagg
     2581 gccttccaca gcaggggaag ggcatcaccc gcttgccctt ctcgatgagg ttcaggtacg
     2641 ccggggagac ccccaggtcc ttggccgcgt ccgtctgctt gatgttccgc gcgagcctca
     2701 gactgcgcag cttcaggcct acgttcgcgt tgagtgcgtt ctcgttcatc tctgcgcgtc
     2761 ctggagggga ggtgtcactc ccagtaccgg ttccctccga catggccact gtgcggaggc
     2821 ttttaccgat ttgcaaccaa cgttttcgag cacgggtccc cgtgttctcg agggaacccc
     2881 gggagggcct cgtccccgtc cccgcgtgtt cactaacggg taagctgttg attttacagc
     2941 gcttgatgtg tgatttcgcg ccttgtacca caggacaacc cgctggttgt caaaatttta
     3001 cccgtaacgt ttaccaacgc tgggacggtg cgccgggggc tgggaaggtt gggtgtggga
     3061 caggaaaccc gggggccggt ctcccgccgt ggttgcatgg gagcacgtgg gcgggttccg
     3121 ctgcgcccgt ttcacctgga gtcaaaaggg ttcgacatgc ctccatccag gccgggtctc
     3181 tccctcgtgg catgggccgc cctgctgggg gcgctgtgct cctgtcttcc cgtgcggccg
     3241 ccgccttccc gcgaggaacc gggccgcctg cgctaccacg tcacctatgt ccgcgagccg
     3301 cggcacgcgc tggaggtggg catcctccgg gtaggggagg gggctccacg cgacttcctc
     3361 ttcagtcaac cgggcggtgt cgagcgggtg cgcatctttg gagcggatgg ctcggagcgc
     3421 gagctgccgg tgtccgccga gggccacgtc ctcgtcccgc cggacacccg ctcgttgcgc
     3481 taccgctacg tgctggacgc gagccggcgc gggagacacg cgggcttctt caccggccag
     3541 ggcgaggacg acgcgaggca ggtcgcgggc cgcgcctggc tgttgcgccc gcgctcggtg
     3601 ggcccggcgc tgcgcgcgga gctcgtggtg gagggcgtgg atgcgctgct gccctgggtg
     3661 ccggacgcgc gcggcgtcta ccagctgcaa ggcgatgatc tggtgaactc gggcttccac
     3721 tcctttggcg gacggcggtg cacggtgcgc ctgccgggcg gtgtgctgga ggtggcggtg
     3781 ctcggccgtc cgtcccacat ggatgacgcg gcgctctgcg cgtggctgga gcgctccgcc
     3841 cgcgaggtgc tgacggtgcg gcgctccttc ccgtaccccc gcgtcaccgt gggcctcgtc
     3901 acggtgccgg cccgcgagga tcccgttccc ttcggcatgg tgctgtggag cacgccgccg
     3961 agcatctcgc tgtgggtggg ccaggacgcg gcgccggccg ccttcacgcg ggactgggtg
     4021 gccgtgcacg agctcctcca cctggcccat ccgcccatct tcccgcgcgt cgcgtggctg
     4081 tccgagggac tggccaccta ctacacggag ctggcgcggg cgcgctcggg ccggcagacg
     4141 ccggagcgcg cgtgggtgga gctgctggcc ggcttcgagc gggcgcgccg cgccgtgggc
     4201 tcgcgcacca tggaggacgt cgtcacccgg ggcgactcgt acctgggcac ctattggacg
     4261 ggcgcgctcg tcgccctgca cctggatgtc gagctgcgcc gcctcaccgg caacacgcgc
     4321 ggcctcgatg atgtgctcga gcggctcgcc gagtccggcc cggctgcaac tttcgacgca
     4381 ttcggcgcgg cggtggacgc catcgccggc cggccgctct tccacgaggt gctgtcccgc
     4441 catctgcccc ggcccgcttt ggccgagctg gagcctctgt tagaagcact gggcgtggag
     4501 cccgcgccgg acggagtgcg gttgggcatc gcccgcgaca gcacgctccg ggacgccctg
     4561 gtggccccgc gttgaggggc ctgtaaccct caaacccgtc gtgcgtatga caccgcgcga
     4621 gcttctcgca gccgttccac cccccgcagt gaaaggacac accatgaaca tcaagaccat
     4681 ggccgccatc gttggaaccc tctccctcgg cacgctcgcc acgggctgtg cgacgtcgaa
     4741 gtcggcggcc cccgccgatc agacgggcac cgccgccgcc agccaggaga agggcggcga
     4801 gtcccagtgc agcggccaga aggccggcac caccgaggag aagggtggcg agcacaagtg
     4861 cggcgccaat ggctgtggtg gcgccaccaa gccgcagtaa cgaatagccc ccggagtctc
     4921 ggggttgtct tccgggcggc tggggcctct tcccgccgcc cgtgtctttt ggtggccgtg
     4981 tttttcctgg aggttcgccg gtgagctacg cgcgcagaca tggactgaag ccgctcggag
     5041 cgggcatcgg gttgcggcgc gagttctacg cacgcctccc ggagacgtcc cgcgccctgg
     5101 actgggtgga gatcatcccc gagaacttcc tcaccctggg cggccgtccg cagcgcgcgc
     5161 tggatgcgtg cgtggagcgc tggccggtgc tgccgcacgg ggtggcgctg aacatcggcg
     5221 ggccggagcc gctcgacgag gactaccttt cggggctcaa ggcgctggtg gagcgggtgg
     5281 acgcgccctt cttctcggac cacctctgct actcgcggct gcggggcgcg tacctgcacg
     5341 atctgttgcc gctgcccttc tcggaggagg cggtggagca cgtggtgccg cgggtgcgcg
     5401 aggtgaagga gcgggtgggc cggcccttcc tgctggagaa tccgagctac tacgcgcgca
     5461 tgccgggggg caccctggac gaggcggact tcctgcggca cgtggccgag gaggcggact
     5521 gtggcctgct gctggacgtg aacaacgtgt acgtgaacgc gcgcaaccac gggtatgacc
     5581 cgagggcctt cctggacgcg ctgccgctgg agcgggtggt gcaaatccac ctggcgggcc
     5641 acgagcagca gccggacgtc atcatcgaca cgcacggggc gccggtctgc gacgaggtgt
     5701 ggtcgctcta ccgctacgtg ctcgagcgca cgggccccgt gtcgaccctg ttggagtggg
     5761 accaggacat cccctcgctg gaggcggtgc tggacgaggc ggaccgggcg cgcgcggtgt
     5821 tggcggaggt ggaggcgcga tgaaaccggg actgcggggc ttcttcgact cgatggagca
     5881 gtacctcacc cggccgggcc cggacgcgct ggagcggctg tacacggcgc acccgggctg
     5941 ggacgcgccg cgctcgcggg tggcgctcta cgggcagatg gtgcgccacc acgtgacgtc
     6001 cacgctggag aagctctacc cgctgacgcg cgcgggcgtg gacgcggccc cgtgggcgga
     6061 gctggtgcgg gcgtacgagg cctcgagccc ctcgcgctcc ttcgagatga accacctggg
     6121 cgagggcttc ccgggcttcc tcgcggacga ggcggcacgg cgtgggctgc cggacttcct
     6181 gccggcgctg gcgcgcttcg agtggacgga cttcgcggtg tacacgtcca tggagccggt
     6241 gccggagcgg gtggagcggc tcacggtgaa cccgacgctg gcggtgctgg agcacccctt
     6301 ccagctctgc gcgtacgtgc ggcggcaggg gaggggacag ccggaggcgg ggcaggagct
     6361 ggcgctgctg tggcgtcacc cggagcggct ggtgacgatg ttcctggccg cgaacgaccg
     6421 ctcgctgctg gcggtgaaga tggcggtgga gggactcacg ccgtcccagg tggcggaggc
     6481 caccggcgtg gccgaggccg acatccgcgc cgtggtggag tcgtgcgtgg cggacggcct
     6541 cgtcctgtcg ccttgaagcc ccaccgggcg gcgggttgcc gcccggcggg gggtggctcc
     6601 ggcgggcacc agggccgccg gagccggtgc cactaccgga tgtcgggctg gcaggtgctg
     6661 cggccacccg cgccggccac gcacagcaga ccatcgcagc acgccgaggc gccgccgcac
     6721 gcctgaccga agccggagca cggcggggtg caggtgcagc tgccgcccgc gcagtcggcg
     6781 ccggtggtgt tgtccaggca gcgcagaccc tcgcagcagg gcgcgacggt cgagcacgcc
     6841 tcgaaggaca gcttgcacac ggggatcgcc tcgcacacgc aggccccgtc cacctcacag
     6901 gggatgggcg gatcctggtt cttctgcacg cactgcaggc cgttgcagca ggtggagccg
     6961 gtgctgcacg actcctggtc cgtgcggcac ccgttgctca cgaagtagct ggcccactgg
     7021 gcgatgtggt tggacgtgtt gatgtcctgg aagggcagcg cgaaggccgt gtaggacgga
     7081 tcgcccgtgc ccaccttgtc cgggtccacc gccgccatcc acagcagggt gccccaggag
     7141 ttctcgcccg aggccgtgac gggctggcgc aggccgtact tgcgcgagga ggagaacgtc
     7201 acccacatga gccggctggt gtcgccgttg ttgccgcgcg tcacgaaggg gctccacttc
     7261 gggtagctgt tggtcaggtt ggcctgcccc ttgtccatca cgccgccctt gttggcgttg
     7321 gccagctcca ccggcgtcgc gttggcctcc agcttcgcgg cccacagctt ggcggtcggg
     7381 tccgtgtcgc cgttgcagtc cgtgtgcgac tcaccggagg ggcaggtgga ctcgttgaag
     7441 acgaggaagg acgagtcggg cgcgatggcc gggtagtagc ggttgcggcc gcccagcgac
     7501 gacaccaccg tcaccggctc gttccagccg ccttccgtct tcgccgtcac catcttgatg
     7561 gcgcccttga agctgcgctg gttcgtgccg gccaggccca tggacatgta ggcgatcttc
     7621 tggccgtccg cgctccagtc cgggtggttg gcggggttgg tcgacgtgcc ggtcccggtg
     7681 atctcgccct cgtaggcggc ggtgtcgccg ttgaagagct tcagcgtgta gcggctggag
     7741 ccgctgtcgg cgtaggtgcc gacgaacttc gtgccatccg ggttccacga ctcgaagttg
     7801 ctcagcttcg tgccactctg cgccaggtcc accttgcccg tggtggaatc gaaggcggac
     7861 aggtcgatca gcgcgagccg gccgtcgttc tggccgttga cctcggccac cagcttcttg
     7921 ccgttgcggc tcagcgcgtg gcaacccacg cagctgacgc tggtgttgat gttgccggcg
     7981 cgcagcacgg gcgtggcgga gggggtgccc gtcccggcga agtcatagcg catcacgccg
     8041 gtgccgcccg acgtcgtcca gtagtagagg gcgcccttga tctcggcgcg ggcgaactgg
     8101 atggagatgg ggtcggagac gcccaccttg cccgcgcccg agtcatccgt ggagcgcacg
     8161 atgagccgga cgggctggcc accgcggttg ctctcggcca ggaacttcca caccttgtcc
     8221 tcgggcgtgt agatgcagcc gcgctggccc gacggcaccg cgcccgtggg gggcgtgaaa
     8281 ccgctgggca ggtagcagcg caggtagacg cgcacgtcgg tgatggtgtt ggagaactgg
     8341 agctcgaaga gcgtgttggt gctgggaccc gacaggaagt ggatctccaa ctgccccagg
     8401 ttgggcggca ccatgacgcc gtggttgggg tagacgatct gcggcttgag cgcgacatcc
     8461 accgcgccgc cgaagcggcc gtccgggttg ggcggcacgg gcgagccact ggggcccgag
     8521 gtgtccgaca ccttctggtc cagcttcacc gtgatgtcgg tggagacgga cttggtgcca
     8581 atgcgggcgc gcacgaagct ggtgccaccc acggtggtgc tcgagttgaa gttcgacccg
     8641 aggaagaggc ccagccgcgt gtcgtcgatg ctgaaggtgg ccttgctcgt cacgtcctcc
     8701 gtgtgtccat cggagtaggt gcccatgacg gtgaatttct gggaggcgct ggtgctgccc
     8761 gtgacggtga gcagcggctt ggtggggctg atgaccagcg agccgatcgt cgggccgtca
     8821 tcaccccctc cgtccgttcc gccaccgtcc ggaccattga gcccgccgtc cgtcgagcct
     8881 ccgccgtccg gacctcccgg agtgggacca caggaacaac cagacagcgc ggtggctgcc
     8941 atcaggatgc caatgagcca ggttttcttc cacatggccg gcgagcgtaa ctctgtttcc
     9001 ggcgtctggc gcgtgcttcg tggacgctgc cctggagggc atccatccac agcacaagct
     9061 tgaaacgcag ccgcaatgag aaggcaggcg tcccccggtt tcccagattc tgagagcgat
     9121 tgcgcccctg ccgtgcggtc agccgggcgt cacggcgggg aagggcggcg ctcggtggtg
     9181 tcgggaggca gtggggtctg gcaccgctcg tcgcggcacg cgaggcccgg agcgcactgc
     9241 tcgttggaga ggcactccac gcagcggcca tccgaggcgc actgggtgcc gcgctcgcag
     9301 ccggtggtgg cgcagccccg gttgacgaag tccacgtcgt cttcggtgcc gggcagctgg
     9361 atcttcactt ccttggactc gctctccgtc acgcacgcct cggtcttctt caccggaaag
     9421 ccgctggcgg aggcctccac ggtgtagcag ccctccggga ggggacccac ccgcaggctg
     9481 ccgtccttgg cgaggggctg ctgttggaag ggggtgccca gcacggacgc ccgtccctct
     9541 tccagctcct ggcgcgcggt gccgcgcacg cgcagctcca ggaagccggc cgcgcggggc
     9601 accacgtctt ccaggcgcgc cgagccgcct ccgggcacca ccaccggcag gcgcaccgcc
     9661 ttgtccgcgg aggccacgat gaagagctcg cccgggccgg ccggcacgcg ctccagcacg
     9721 aaggagccgt ccgcggccac ggtgccgcgc acctccgggt ggcccaccag cgacaccagg
     9781 gccaccgacg gatcggcctc ggtgagctgg ccccgcacgg tgcccgtccg gaagggggtg
     9841 ttgtcgaaac ccccgcatgc actcgcgacg agggcgaggg ccatcatcac gctgtaggtg
     9901 gtctggcgca tcagaagcgg taccccactc cggcccatcc gccggagaaa cccacggcct
     9961 gtccctgccc atccaccacc acgtacgtca ccatcagctg cgtctgcgcg ctcagctcca
    10021 gccgctcgcc cagccgccac accacgccgc ccaccacgcc cgggctgacg gtgaagtact
    10081 gctgcccacc ggtgaaggcc tctgtctgga aggaccgctg gaggaacaga gcggccacac
    10141 gcgggcccgc ataaagcgac aaatgctccc accgccaggt gtagggcacc gcggccccca
    10201 tcgacagcga ggtgtaggtg aaggggacgg aggtgccggg cgccaggtgc aggttctgcc
    10261 ggccccggcc gccactcaga tcgaagacga ggctcaggtc cggcaacggc cgctcctcca
    10321 gccgcagcac cagcgccagc tccggcgagg cgggcagcag ctcgttgcgg ctgcgtgcgt
    10381 ccacgaagga gaacatgccg cccatcaacg acagcgagcg cctcgggaag gtctccgaca
    10441 gcaggcgctc cagcggcagc cgctcgccca cggagatgtc caccacctcg cgcagcagga
    10501 cgtcctcccc cttggtcagc tccacggtgc gccggcccgg cggcaccgcg gcgcccccgg
    10561 gcagctccgt gcgcgtctct ccgtccacct tcagcgtgaa gccgtccagc cgggggttgt
    10621 acgagaagag ctccgggcgg cccgtccggt cgatgtggcc ggagagcacc accggatccg
    10681 cccccacctc gaggatctcc gccgagggcc gctgccgccc ctgggtgaag gcgtaggtgg
    10741 agcggcgcgc gtgatcatgc gcctcggtgg cggtgacggc gccgtcggag ttgcggtccg
    10801 ccgcgccatt cagcccgtcg atgaggaagt gggtgtagat gtc
//
