LOCUS       NZ_CP011509            21074 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Archangium gephyra strain DSM 2261 chromosome, complete genome.
ACCESSION   NZ_CP011509
VERSION     NZ_CP011509.1
KEYWORDS    RefSeq.
SOURCE      Archangium gephyra
  ORGANISM  Archangium gephyra
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Archangium.
REFERENCE   1  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Genome assembly of Archangium gephyra DSM 2261
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) Protein Science and Engineering, Institute
            of Microbial Technology, Sec-39 A, Chandigarh, Chandigarh 160036,
            India
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: HGAP Pipeline v. SMRT v2.3.0
            Coverage                          :: 79.3
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001027285.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:37:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,001
            CDSs (total)                      :: 9,898
            Genes (coding)                    :: 9,822
            CDSs (with protein)               :: 9,822
            Genes (RNA)                       :: 103
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 28 of 76
            Pseudo Genes (incomplete)         :: 45 of 76
            Pseudo Genes (internal stop)      :: 6 of 76
            Pseudo Genes (multiple problems)  :: 3 of 76
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 688566
            Orig. end                         :: 709640
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="4"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11074](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    667..679
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    complement(1436..1453)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    complement(1913..1927)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.85"
                     /tool="antismash"
     misc_feature    complement(2332..2345)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.85"
                     /tool="antismash"
     misc_feature    complement(2518..2531)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.85"
                     /tool="antismash"
     misc_feature    complement(2704..2717)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.85"
                     /tool="antismash"
     misc_feature    complement(3073..3086)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.85"
                     /tool="antismash"
     misc_feature    complement(3259..3272)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.85"
                     /tool="antismash"
     misc_feature    complement(3383..3397)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(3801..4127)
                     /locus_tag="AA314_RS02935"
     CDS             complement(3801..4127)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS02935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_047861375.1"
                     /transl_table=11
                     /translation="MNLITAELLFRGIKELSADDLLVRATDVFEWCARLPVDYRGSGWN
                     NQAIWDADREEARGQHRLLKFKCGTTRQARVAWGLVHHADKVRTAAKLAGWRELHWDGK
                     RWVW"
     gene            4342..5076
                     /locus_tag="AA314_RS02940"
                     /old_locus_tag="AA314_00609"
     CDS             4342..5076
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS02940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_00609"
                     /product="hypothetical protein"
                     /protein_id="WP_147332937.1"
                     /transl_table=11
                     /translation="MLHRDSGLYLGSMGCMVTRETNAFVRQYNARIRALREELGLPSWA
                     PGSRLPERRRLLALLSDAQPVTTGEQLEALGLRSLGYSLRDSDLVPVVVSRRWEDLGLL
                     LLGSDVSAMKGCIDVLDLREETWMVSEEFDRREDGLMPWDSLPRDAKDAVRARHAAAKA
                     ADAEVQARHRAELEARNRRAELNRQRCPELVEEMKVRDFACPHCQVLTRGFRFLPRSES
                     FVCPSCSRSFNALAFASPAKDR"
     gene            5186..6574
                     /locus_tag="AA314_RS02945"
                     /old_locus_tag="AA314_00610"
     CDS             5186..6574
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS02945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_00610"
                     /product="hypothetical protein"
                     /protein_id="WP_047854200.1"
                     /transl_table=11
                     /translation="MRHLLPVLALLLLAACPRAPEELTPPPVDPPVPEQPSGLQGSLTV
                     HLRDWNLVPKEFLQSAYVLLGDGSRFRQAVDDNGDVHFQDAAIVGSQDVTVVLTMKSET
                     PTVLVGSFLAIGQPEVWLPVVDSLETTEPPPDPGPKLATVSGKVTGMSGAAEHFVYVIA
                     AGQGLSGGGPVASDGSFRFNVLGAEPGQVDLIAWEEKFDPEYGTYGDVLVRAGRVRGIA
                     LARDQVLGGLELALDHAADQSLGVTVKGAEHYGSPATVTLRFHEDTLGFFTSYAKGTSP
                     LSVPTLAMTPPFDTTRRLLSTSLGRSEVLPAGYAYALNPIDNGPAATLTLLSPMTSSSP
                     ALGACASPPTTPLAGLGLRWSVDAAANVGQLDFLLQEPAGPGAGFSWRVLAPSSRTSFT
                     PFPLPSEVSPLSTFPPGLYSLKLQSSFRGDVEGYASAFAQHVSKPSYLVESRRTELTGC
                     FTLQ"
     gene            complement(6561..7526)
                     /locus_tag="AA314_RS02950"
                     /old_locus_tag="AA314_00611"
     CDS             complement(6561..7526)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015346882.1"
                     /locus_tag="AA314_RS02950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00611"
                     /product="YafY family protein"
                     /protein_id="WP_047854201.1"
                     /transl_table=11
                     /translation="MSRPTTRVLTVLELLQTHGRMSGSQLAQRLEVDRRTVRRYIALLE
                     ELGIPITAERGRDGAYMLVAGFKLPPLMFTDDEALALSVGLLAARGLGLAEAAPAVASA
                     QAKLERVMPATVKRRVRAIDETVTLELSRSTAPRDNAALAALSTASQGQRRVQLRYRAA
                     EREDSERDFDPYGLAWRGGRWYVVGRCHLRDGLRSFRLDRVQSVQPLDVSFSRPEGFDA
                     LAHLTLSVATLPREFTVEVLLETDLAAARRQVFPAFGVLEEVAGGVLLRGQTDDLGWFA
                     RELARLPFSFEIHRPDALREELAARARRLLQQATRAVTGA"
     gene            7624..8259
                     /locus_tag="AA314_RS02955"
                     /old_locus_tag="AA314_00612"
     CDS             7624..8259
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002629839.1"
                     /locus_tag="AA314_RS02955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00612"
                     /product="LysE family translocator"
                     /protein_id="WP_047854202.1"
                     /transl_table=11
                     /translation="MEQTAHLWLFFVLVFGVVVLPGLDMAFVLASSLTGGRKAGLSAVA
                     GIIAGGACHVAAGATGVAVLLKVVPSAFNVMLWMGALYVAWMGISIFRSGAAFSAAPLG
                     EKQPPTATFRRGVLTCLLNPKAYVFMLAVFPQFVRPEYGPLWIQALVLGAIIAVTQGAV
                     YGAIALAADRARGWLESNPAANVAAARVVGGLMTLAAVVTVFEGWRSV"
     gene            complement(8279..9172)
                     /locus_tag="AA314_RS02960"
                     /old_locus_tag="AA314_00613"
     CDS             complement(8279..9172)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637769.1"
                     /locus_tag="AA314_RS02960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00613"
                     /product="TIGR02266 family protein"
                     /protein_id="WP_047854203.1"
                     /transl_table=11
                     /translation="MNAPSPSPAHPPSRETELARAESELASQEARLGEQLTRAAAEAET
                     LSRRLLELRQQVERLTAERPGDEDVRAAGTRLESASVHTGLTEESREQALASRNEALEA
                     RRRAAEDAQRTLNSLQQLNARAQQELAEAEAGLKRSAEAAARAQREREAAARAQRERES
                     TQGRAARPAKAQGNTTQLDPHPQGARSRPRMVAAIDQRSDSNFFTGFTTDIHEGGIFVA
                     TVQSVPRGTTVDLDVLLPGTRSMTVTGVVRWTREVNDKTPELMPGLGVKFTYLPPEVTS
                     VISDFVATREPMFFPD"
     gene            complement(9276..10004)
                     /locus_tag="AA314_RS02965"
                     /old_locus_tag="AA314_00614"
     CDS             complement(9276..10004)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS02965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_00614"
                     /product="hypothetical protein"
                     /protein_id="WP_047854204.1"
                     /transl_table=11
                     /translation="MRRVLRHIEQHKAELARSPFLTFLGDASVEPRLRFGFAPCMAPFV
                     MGFADLNKYVLRDEASEDPIQRLINTHTREDDHHWGMFLRDLRTLELNAPMDFTGALEQ
                     LWGAHNQKARQLIYGLVALVSAESPVMRLVIVESVEAAGSVGFSRFTQVARELEAKTGK
                     RLLYFGEAHEGLETGHLMGSGNVEETIAGLELTAEQVERARGLTDRTFALFHAMGEELL
                     AHARRGLEGARPEPALRRGA"
     gene            complement(10001..11074)
                     /locus_tag="AA314_RS02970"
                     /old_locus_tag="AA314_00615"
     CDS             complement(10001..11074)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF023417.4"
                     /locus_tag="AA314_RS02970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00615"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_047854205.1"
                     /sec_met_domain="indole_PTase (E-value: 3.7e-92, bitscore:
                     308.3, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPIPWQSLRSFGSERLDALCHAVGFGAEDTRTVRRTFELMCGA
                     WGQRPLGDKPAWRSDITDDHTPFELSLAMEAGQPEVRFLLEAQGQPTTLRSSWEAALAL
                     NERLRHELGVSLERFEQVKALFEPVDARARFGLWHAVCVVPGGAPALKVYLNPFARGPE
                     GAEALVRQALERLGCAEAWHVLTRAMRRESGDRPVYFSLDLSSHRAARIKVYLAHPEAL
                     AEELEDVMALAPEYVPGEARDFCQRLRGATGRFTGARPTLTCLSFTSDAPGRPSSVTLH
                     FPIRCYADHDADALRRIRPLLDPESRGLLERAVGALARRPLEDGVGLIQWVSFRRQGGG
                     RRATFYLATEAYSGAQP"
     misc_feature    complement(11151..11164)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.67"
                     /tool="antismash"
     gene            complement(11261..12613)
                     /locus_tag="AA314_RS02975"
                     /old_locus_tag="AA314_00616"
     CDS             complement(11261..12613)
                     /EC_number="6.5.1.8"
                     /GO_function="GO:0008452 - RNA ligase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637768.1"
                     /locus_tag="AA314_RS02975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00616"
                     /product="RtcB family protein"
                     /protein_id="WP_047854206.1"
                     /transl_table=11
                     /translation="MSWTQRLEKVAEGHFVLPKTKTMRVDAHLFLSDKLLWGQGPELPG
                     LEEGVFDQVVNAASFPGVTRVAVTPDCHLGYGVPIGTVVETDGILLPTAAGYDIGCGMV
                     QLKTTLTAEDVADPAKRREWINEVTKRIAVGVGASRVQKQRSVNARTFAEVVRHGAKAL
                     GRTASTTERDFIPVEDDRVDIPERAYDKRDQLGSLGGGNHFTEMQVDEDGRVWVMLHTG
                     SRGFGWNIAKHYFVEGAAALGLSKRSEDFIWLDAESRLGREYWNLHNMAANFAVANRLI
                     IGEAVCAALEEVFGGTADIYYEISHNLIQKEAGKFVARKGATRAFPGGHPALRKTQWEK
                     TGHPILIPGSMETGSAILFAEEGAEQSIYSVNHGSGRRMSRGEARRVLNQSETDRRMAE
                     AGILLNTRTTPLDESGPCYKNLDDVLDTVEMAGLAKVDKRLKPIACIKGAD"
     gene            12810..13100
                     /locus_tag="AA314_RS02980"
                     /old_locus_tag="AA314_00617"
     CDS             12810..13100
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020477948.1"
                     /locus_tag="AA314_RS02980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00617"
                     /product="hypothetical protein"
                     /protein_id="WP_047854207.1"
                     /transl_table=11
                     /translation="MGILGALLVAVTVNAGPVEVKTAPVFNPAVCSKKRVDACGCHHVY
                     GVRHCHPKRKSEHCEAMVQAEPAEQNVSTEQELFSHEPEPATEETADSATL"
     gene            13221..14489
                     /locus_tag="AA314_RS02985"
                     /old_locus_tag="AA314_00618"
     CDS             13221..14489
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1102: glycosyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012427.4"
                     /locus_tag="AA314_RS02985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00618"
                     /product="glycosyltransferase"
                     /protein_id="WP_047854208.1"
                     /sec_met_domain="MGT (E-value: 2e-42, bitscore: 145.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLVVACGTRGDFQPMLALATALRDAGHEVLLGATPTFASEAAA
                     LGVPFAPVGVDFQRMLAEHRAQLDHDNPLAAIRLMNRVMPEVIRAEWHSLLPLLPGQQL
                     VVAGGAALSARSAVESVRLPFRYVAYTPQLLPSAWHPPFMIPLTRTPRWFNRLGWWGMG
                     AVYDRLLLPVLNELRRGQGLPALTDVIRQAFPSEPGMVLLAADPELAPAPPDLSVHQVG
                     AFHLADPRPLPAEAERFLAEGEPPVYIGFGSMPDAAPERTSLLLAEAARRAGCRALLSS
                     GWAGLGEGSLGSHVQVVGPLSHGALFPRLAGIVHHGGAGTTAASTRAGVPQLVVPHMLD
                     QFMNARYVHTAGIGLSLSRNRLGVERLASALLRLREDPALRARAAHVGERVRARNSLAA
                     AVALLEQAAREGLTPRPSPSLPT"
     gene            complement(14455..15102)
                     /locus_tag="AA314_RS02990"
                     /old_locus_tag="AA314_00619"
     CDS             complement(14455..15102)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373980.1"
                     /locus_tag="AA314_RS02990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00619"
                     /product="hypothetical protein"
                     /protein_id="WP_047854209.1"
                     /transl_table=11
                     /translation="MGVRELKEQALDLYSRRKFTECARTYGKLLELEPRDPHLYVRHAE
                     AWRRAGDRQKAISSYRTAAELLLQLGCEARARAALKVALELDPRDNEVARALERLSHAN
                     APRQAVHVPPSVPPPSRIPEHKRDMVELHTRQANVPGRLALPPAPAAPAAPLPSPAEVR
                     RLSGNTLAMRAAPGTRWVVISSRTPLTAYEVDDLERVMSREFTLEVTVTAEE"
     gene            15296..16210
                     /locus_tag="AA314_RS02995"
                     /old_locus_tag="AA314_00620"
     CDS             15296..16210
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013936762.1"
                     /locus_tag="AA314_RS02995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00620"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_047854210.1"
                     /transl_table=11
                     /translation="MSQPSPLARLLVPHLRPEARGYAEVPALETVLAELLASAHTAWPR
                     VRLEDAVFLRYLAERLGPTSEPERTLRALPAADLFLACACVHGDAAAQAALDAHFLPKV
                     AAAVARVHPGADAVSEVCQVLREKLLTSEGGQPPRLASYLGQGPLAAWLRAAAVRTALN
                     LRRSAQRQARAEEEALAEATLPGGTHPELEHLRQRHRADFQAALAEALAALPSRERTVL
                     RLHLVEGLSLERIGTVYRTHKSTVSRWLARAREEVLAGTRSRLTERLRLSSGELHSLLR
                     DVPVQLDQSLSSLLATTGDSEGP"
     gene            16291..16641
                     /locus_tag="AA314_RS03000"
                     /old_locus_tag="AA314_00621"
     CDS             16291..16641
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025014.4"
                     /locus_tag="AA314_RS03000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00621"
                     /product="pilus assembly protein N-terminal
                     domain-containing protein"
                     /protein_id="WP_047854211.1"
                     /transl_table=11
                     /translation="MKNVKKLMGVLAVTAVAVLGTAAGAEQVAPAAAQGTPAAPAETIH
                     VKKGEVYTLEVKDLVRIAVGDPETAGISVADKTDKKDATGVRIAGLKAGETILLTWTKD
                     GTRKAYTLVIRG"
     gene            16662..18104
                     /locus_tag="AA314_RS58255"
                     /old_locus_tag="AA314_00622"
     CDS             16662..18104
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637763.1"
                     /locus_tag="AA314_RS58255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00622"
                     /product="protein kinase"
                     /protein_id="WP_276326891.1"
                     /sec_met_domain="Pkinase (E-value: 1.7e-34, bitscore:
                     118.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAARACDNPDAMPLESRLRAPDGCPDENVLAGFASGALAHEDTPR
                     LEQHLDGCAACRALVAAVAAEASQPGDSLAPTCLDTGTPTLPMHPGAPALEPGAQVGRY
                     VVEALLGEGGMGMVYAARDPALGRTVALKLLRPGGGGDEGRARLVREAQAMARLSHPNV
                     LPLFELGTEGDSVFLAMERVEGPTLAGWLRERERPWREVLALFMRAGEGLAAAHRAGLV
                     HRDFKPANVLVGADGRPRVTDFGLVRHEAGLDEALPGDAAAGDTGEALTRAGAAPGTPA
                     YMSPEQLAGREVDARGDQFSFCVALHEALYGLRPFDARARGEARWSRVPVPRGPRLPGH
                     VRAALERGLSLSAEARFASMEALLGALAAPSGPRWLPVVTVVAGLGLVLAGADVVVWRT
                     RAPEAVPAQEAMPVALMPGTPVELEIPGMVRVAVGTPDVVEVKVLEADKVQLLPLATGT
                     TTMLVWTRDGTRRTYNVSVGPY"
     gene            18179..18787
                     /locus_tag="AA314_RS03010"
                     /old_locus_tag="AA314_00623"
     CDS             18179..18787
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021361.4"
                     /locus_tag="AA314_RS03010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00623"
                     /product="DUF2059 domain-containing protein"
                     /protein_id="WP_047854213.1"
                     /transl_table=11
                     /translation="MRSINPLASWRWCLLAVLAVGCAHSSTGPAAVTAEPAPRAQAAPV
                     DANLAEARALTDQMFGPEAQATQRKQRKVRRLMVLTGAEDTGRQMLEMMTSHFEQSSSI
                     PPGFMEKFREAAQQESIVDLLVPVYMKHFSEEDLDAAITFHESPAGKRFLAAQPRVLQE
                     AKEVGEQWGVRLAEKALRALVKEESERKPTPARHEGQEL"
     misc_feature    complement(19260..19274)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    21025..21040
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.41"
                     /tool="antismash"
ORIGIN
        1 tttctggctg cggcagttcc cccactgtcg atgagccctc gccctttact gtgtccgggc
       61 aatccctggc aggtaccacg tgcgtgacgc tccagcgggg gagcgcgggt acagtcgctg
      121 acacccacat ctccagccag cagcccgcgc atactgcggg ctccgagccc gtcgctcatg
      181 tgggagacgc cggccgctac acccgccagg ccctgctcca cttcgacacc tcctccattc
      241 ctccccacgc caccctgacc tccgccaccc tctccctctg gcgacagggc tcctctcacc
      301 cctcccccct cactgcccac gccattacct cgccctggca ggagcagtcc gtttcctggc
      361 aagacttctc ctcgtccttc gctccccagg tagccgccac cttccaggcc agcaggacgc
      421 cgggcgcgct ttccacctca ctgagggagc tcgtgtccat ctgggtgcgc aaccccaccc
      481 tcaaccatgg cctgctgctc cagcagtccg agggccactc gctgctggcc acctccgagt
      541 cccccaacac ctcgcaccgg cctgccctcc aggtctgctt cttcctgccc gactcctctc
      601 cggccacctc ctccgctccg agcctcctgc tgcgcgtgct ggatgattcc gggcagcccc
      661 tttccggtgc cgctgtctct tcttcctcgt cccaactgcc caccgatggc gcgggctacg
      721 ccgtgctcga caatctgccc tctggcttct tctccgcacg cgtcgaggcc gttggtttcg
      781 ctcccgccgt cgtctccttg cacctgcctc ccggcgctcg cgcctcccat gaggttcgcc
      841 tgttgccgct gggacagccc cagcccttcg ccgtctcggc gggggccacc ctggagcacg
      901 gcaccctgcg tgtctccatc cctccccacg ccgtcgtcga tagcgacgga cggcctgtct
      961 ccggcaccgt ccaggccacc ctcgttcccc tggaccccac caccgtgccc acctcgtctc
     1021 tccctggccc cctggagggg ctcgtttccg agggggcctc cgagcccgtt cccctggagt
     1081 ccttcggcat ggccgaggtc tccctctggc aggacggcag gccgctgcaa ctggccccag
     1141 gcgccaaggc caccctggag ctgttgctgc cttcatccgc ctcgtctcgg ctgagccccg
     1201 gtgatgcgat ccccgcctgg tggctggaca ccgcgcgtgg cctgtgggtg cgcgagggca
     1261 cgggcaccgt ccagcactcc tccctccacc ccggccgtct ctcctgggtg gtcgaggtga
     1321 gccacttcac ctggtggaac tgcgacgccc ccctgtccga caggagttgc gtcgacgtcc
     1381 tcgtccgcta ccccagtggc ctgcccgccc ctggcgccca ggtgggtgcc accggtatca
     1441 gctatacggg ctccagccgc accgtgtaca cgggcgctga cggtcgcgcc tgcgtcgaga
     1501 tcaaacgcgg tgccaccgcc cgtgtcttcg ccgggctgtc tggtgagact ctcggcgagg
     1561 ctaccgtgac aggctcggcc gagcccaccg cctgtggtgg cggtgcctgc acacccgtgt
     1621 cactcaccat caccccgccc gtctgcattc cggggagtac ccagacgtgt acctattcgg
     1681 ggcccgcgag caccaaggac gtcggcctgt gccgcgccgc ccaccgctac tgcaacaccg
     1741 ccggtaccgc ctggggcgcg tgtgagggag aggtgctgtc ggcctccgag acctgctcca
     1801 acaccttcga tgaggactgt gatggtgcga ccaacgaggg atgccgttgc ggctcgtctt
     1861 gttactcagg cccgccgggc accagcggcg ttggggtctg ccgcgctggc accatttact
     1921 gcaaattcgg tgtggacccc tactgcgcgg ggcagacact gccctcaacc gagacctgca
     1981 cgacatccgt agaagacgat gactgcgacg gctccctcac ctgcaccaat ccgctcacgc
     2041 aggcttggcg ctatggtaac gtctcgtgcc agtactctcc tcaactcctc atgagttcgg
     2101 acggcaacct catcgtttcg ggcttgttcc ttgggacgct ggagttcggc ggtggcgtcg
     2161 tcctgacggg ttccacctcg ggctatgcgg ctttcctcgc gaagttcgat gcgagcaccg
     2221 gcggggcact ctgggccacc atgctcgcgt ccacgcaatg ggcccaggtt caccatattc
     2281 agaaggacgc cagcggcaac ctcattgtcc tgggccagtt ccaaggcaac ctcacggtgg
     2341 gtggcaccac gctgtccaat ccagagggca ctgatgggtt cgtggtgaag ctagatgagg
     2401 cctctggggc tgtgctgtgg ctctcccacc tcaacagcaa tggttccacc tacatataca
     2461 cgccggtggt ggacccgagc ggtaacttca ttgtctcggg cgagttctac gacaacctca
     2521 cggtgggtgg caccacgctg tccaatccac ggggcaccga tgggttcgtg gtgaaactgg
     2581 atggggccac gggggggctc ctatggctct cacacctcga cagcgcggat gtgagccacg
     2641 catccacgcc agtggtggac gcgagcggca acctcattgt ctcgggccgg ttcgaaggca
     2701 acctcacggt gggtggcatc acattgtcta gcccaaccgg ctacgatgga ttcgtggtga
     2761 aactggatgg gggctcgggg gctcgcctgt ggctcgtaca tctcgacagc acgcgttcca
     2821 cctactcagc cccgctggtg gtggaggcga gcggcaacct cattgtctcg gataacttcg
     2881 acggcaactt cacggtaggc ggcaccacgc tgtccaattc agggggcact gatggggttg
     2941 tggtgaagct ggatggggcc tcgggggctg tcctgtggct cgtacacttc gacagcaggt
     3001 acacctacgt atccaggccg gtggtggatg cgagcggcaa cctcattgtc ctgggccagt
     3061 tccaaggcaa cctcacggtg ggtggcacca cgctgtccaa tccagagggc attgatgggt
     3121 tcgtggtgaa gctggatggg gcttcggggg ctgtcctgtg gctcgcacac ctcgacagca
     3181 cgaatttgag ttacgtatcc acgccggtgg tggacgtgag cggcaacctc attgtctcaa
     3241 gccagttcca aggcaacctc acggtgggtg gcaccacgct gttcaatcca gggggcaccg
     3301 atgggttcgt ggtgaagctg gatgggactt ctggggcccg cctgtggctc gcacacctcg
     3361 acggcacgaa ttacacctac gcatccacgc ccgtgatgaa tgcgagcggc aacctcattg
     3421 tctcgggcta cttcgacggc aatctgagag tgggcggagt catcctctcc aattcaggca
     3481 gccgcgatgg gttcgtggcg aacttgcagg caagctctgg tgcgatttcc tgggtccggc
     3541 atttcgaaag cacctccggg gtcagcctca gtccaacact cgtggtgaat ccagagaaca
     3601 tcttcatcgc gggctccttc gacggcattc tcaacacagg gggggcggca ccgctgacga
     3661 gcgcggggtg ttacgacatg ttcctctcca gaatcgcctc cacgccttga tacgcagtgc
     3721 cccgactcgc accgtggccg ggggcttctt ctccgaagcc acctttgccg tcttccggga
     3781 agagtacggt gcctcctttg ctaccagacc cagcgtttcc cgtcccagtg cagctcgcgc
     3841 cagcccgcga gcttcgcggc agtgcggacc ttgtccgcat ggtggaccag tccccacgcg
     3901 acccgcgctt gccgtgtcgt tccacacttg aacttcaaga ggcggtgctg cccgcgggct
     3961 tcctcgcggt cggcgtccca gatggcttgg ttgttccagc cgcttccccg gtaatccaca
     4021 ggaagccgag cgcaccattc gaacacgtcc gttgcacgga ccaggaggtc gtccgctgag
     4081 agttccttga ttcctctgaa gaggagctct gccgttatga ggttcatgcg caaacgaaac
     4141 gctggatgag aggaccctgt ccagtatggc gcggtgcctc agctcgagtc cgtggctcct
     4201 cgttcgcggg accgctactg tcgcgccatg tccaaggagc cctccagccc tcctctttcc
     4261 gccgaacagc aggcccgtgc cgactgggaa gacgggtccg cccggttcct caccatcgga
     4321 ttgatgaggc cctggcagcc catgctgcac agggattccg ggctctatct cggctccatg
     4381 gggtgtatgg tcacccggga gaccaacgct ttcgtcaggc agtacaacgc tcggatccgg
     4441 gccctgcgcg aggagctcgg tctgccgtcc tgggcgccgg gaagccggtt gcccgagcgt
     4501 cgccgcctgc tggcgttgtt gtcggatgcc cagcccgtga cgaccgggga gcagctcgag
     4561 gcgctgggtc tgcgctccct gggctactcg ctccgggatt ccgacctggt tcccgtcgtg
     4621 gtgtcccggc gatgggaaga cctgggattg ttgctgctgg gcagtgacgt ctccgcgatg
     4681 aaggggtgca tcgacgtcct cgacctgcgc gaggagacct ggatggtctc ggaggagttc
     4741 gaccggaggg aggacggatt gatgccgtgg gactcccttc cccgggacgc caaggacgcc
     4801 gtccgagccc gccatgcagc cgcgaaggcc gcggacgccg aggtgcaggc acgtcaccgc
     4861 gccgagctcg aggcccgcaa ccgccgggcg gagctcaacc ggcagcggtg tcccgagctc
     4921 gtcgaggaga tgaaggtgcg ggacttcgcc tgcccgcact gccaggtgct cacgcgcggc
     4981 ttccgcttcc tgccccggag cgagagcttc gtgtgtccga gctgctcccg ctccttcaat
     5041 gcgctggcgt tcgcctctcc cgcgaaggac cgttgaggcg tcatccggac tcgcggaagg
     5101 gccgcgtgcg actccgcgtg ctccggcaac cgggtagacg cgtgctcctc taggatgggg
     5161 ggcctctttt ccccgaggtc ctccgatgcg ccacctgctt cccgtgctcg ccctcctgct
     5221 cctcgccgcc tgcccccggg cccccgagga gctcactccg ccgcccgtgg acccgcccgt
     5281 gcccgagcag ccctcggggc tccagggctc gctcaccgtc cacctgcgtg actggaacct
     5341 cgtgccgaaa gagttcctcc agagcgcgta cgtcctcctc ggagatggca gccggttcag
     5401 gcaggccgtc gatgacaacg gggacgtgca cttccaggat gccgccatcg tgggctctca
     5461 agacgtcacc gtggtgctga cgatgaagag cgagacgccg acggtgctcg tgggctcctt
     5521 cctcgccatc ggccaaccgg aggtctggct gcccgtcgtg gactcgctgg agacgaccga
     5581 gcctcccccc gacccgggcc cgaagctggc caccgtctcc ggcaaggtga cgggcatgag
     5641 cggcgccgcg gagcacttcg tctacgtcat cgcggccggc cagggtctct ccggcggagg
     5701 ccccgttgcc tcggacggct ccttccgctt caacgtcctg ggtgccgagc ccggccaggt
     5761 ggacctcatc gcctgggagg agaagttcga cccggagtac gggacctacg gtgacgtcct
     5821 cgtgcgtgcg ggccgtgtcc gcggcatcgc gctcgcccgg gaccaggtgc tcggcggact
     5881 ggagctcgcg ctcgaccacg cggcggatca gtcgctgggg gtgacggtga agggcgcgga
     5941 gcactacggc tccccggcca ccgtcacgct tcggttccac gaggacacgc tgggcttctt
     6001 cacctcgtac gccaagggca cctctccgct ctccgtcccc accctcgcga tgaccccgcc
     6061 cttcgacacg acccggcgct tgctctccac ctccctgggc cgttccgagg tcctgcccgc
     6121 cgggtacgcc tatgcgttga atcccatcga caacgggccg gccgcgaccc tcacgcttct
     6181 gtccccgatg acgtcctcct ccccggcgct gggggcctgt gcctccccgc ccaccacccc
     6241 gctcgcgggc ctgggcctcc ggtggagcgt cgatgccgcc gcgaacgtgg ggcagctcga
     6301 cttcctcctc caggagcccg ctggcccggg agcgggtttc tcctggcgcg tgctggctcc
     6361 ctcctcccgc acctccttca cgcccttccc cctccccagc gaggtgtcgc ccctctccac
     6421 gttcccgccg gggctctatt ccctcaagct ccagtcctcc ttccgcgggg acgtcgaggg
     6481 gtatgcgagc gccttcgccc agcacgtcag caagccctcc tacctcgtcg agtcgcggag
     6541 gaccgagttg acggggtgct tcacgctcca gtgaccgctc gcgtggcctg ctgaagcaat
     6601 cgccgggcgc gggccgcgag ctcctcgcgc aatgcgtccg gccggtggat ttcgaaggag
     6661 aagggcagcc gtgccagctc ccgcgcgaac cagcccaggt catcggtctg gccgcgcagc
     6721 agcacgcctc cggccacctc ctcgagcacg ccgaacgcgg gaaacacctg gcgccgcgcg
     6781 gccgcgaggt cggtctcgag cagcacctcg acggtgaact cccgaggcag cgtcgcgacc
     6841 gagagcgtca ggtgggcgag cgcgtcgaac ccctcggggc gggagaagct cacgtccagc
     6901 ggctgcacgg attgcacgcg gtccaaccgg aacgagcgca gtccgtcgcg caggtggcac
     6961 ctgcccacga cgtaccaacg cccgccgcgc caggcgaggc cgtagggatc gaagtcgcgc
     7021 tcggagtcct ctcgttccgc cgcgcgatag cgcagctgca cgcgccgctg gccctgggac
     7081 gcggtgctca gcgcggccag tgcggcgttg tcacggggcg cggtggagcg ggagagctcg
     7141 agcgtcaccg tctcgtcgat cgcgcgcacg cgccgcttca cggtggcggg catcacccgc
     7201 tcgagcttgg cctgggcact ggccaccgcg ggggccgctt ccgccagccc cagcccgcgc
     7261 gccgcgagca ggccgaccga caaggccagg gcctcgtcgt cggtgaacat cagcgggggc
     7321 agcttgaagc cggccaccag catgtacgca ccatcgcgtc cgcgctcggc ggtgatgggg
     7381 atgcccagct cctccagcag ggcgatgtag cggcgcaccg tccggcgatc gacctcgagc
     7441 cgctgggcca gttgcgagcc gctcatccgg ccgtgcgtct gcaacagctc gagcacggtg
     7501 agcacgcgcg tcgtggggcg ggacatgggg agcagcctgt ttcgaatgag ggccggttcc
     7561 gccctatatt ccttctaggg aggagcggtt ctccagtcct ttcgcctcac gggagtcttc
     7621 gtcatggagc agaccgcaca tctctggctc ttcttcgtcc tggtgttcgg agtcgtcgtc
     7681 ctcccggggc tcgacatggc ctttgtgctc gccagctcgc tgacgggcgg gcgcaaagcg
     7741 ggcctgtccg ccgtggccgg aatcatcgcg ggtggtgcct gtcacgtggc ggccggtgcg
     7801 acgggggtcg ccgtcctgct gaaggtcgtc ccgtccgcgt tcaacgtgat gctgtggatg
     7861 ggcgccctgt atgtggcgtg gatgggcatt tcgatcttca ggagcggagc ggcgttctcg
     7921 gcggctcccc tcggggagaa gcagccgccc acggccacgt ttcgccgggg agtcctcacc
     7981 tgtctgctca acccgaaggc ctatgtcttc atgctggccg tgttcccgca gttcgtgcgg
     8041 ccggagtatg gacccctgtg gatccaggca ctggtgctcg gcgccatcat cgcggtgacc
     8101 cagggcgcgg tgtatggcgc catcgcgctg gccgctgacc gggcgcgcgg ctggctcgag
     8161 tcgaatcccg ccgccaacgt cgcggccgcg cgggtcgtcg gcgggctcat gacgctcgcc
     8221 gcggtggtga cggtcttcga ggggtggcgg agcgtttgag gcgcggtccc gagggggctc
     8281 agtccgggaa gaacatcggc tcgcgcgtgg ccacgaagtc cgagatgacc gacgtcacct
     8341 ccggcggcag gtaggtgaac ttcacgccca gccccggcat cagctcgggc gtcttgtcgt
     8401 tcacctctcg cgtccagcgc accactcccg tcaccgtcat ggagcgcgtc cctggcagca
     8461 gcacgtccag gtccaccgtc gtcccgcgcg gcaccgactg caccgtcgcc acgaagatgc
     8521 cgccctcgtg gatgtccgtg gtgaagcccg tgaagaagtt cgagtcgctg cgctggtcga
     8581 tcgccgccac catcctcggc cgggagcgcg ccccctgcgg atgggggtcc agctgcgtcg
     8641 tgttcccctg cgccttcgcc gggcgagccg cccgcccctg cgtggactcg cgctcccgct
     8701 gcgcccgcgc cgccgcctcg cgctcccgct gcgcccgcgc cgccgcctcc gccgagcgct
     8761 tcagccccgc ttccgcctcg gccagctcct gctgcgcccg cgcgttgagc tgctgcagcg
     8821 agttcaacgt ccgctgcgcg tcctccgccg cccggcgccg ggcctccagg gcctcgttgc
     8881 gtgacgccag ggcctgctcc cgcgactcct cggtgaggcc ggtgtgcacc gacgccgatt
     8941 cgagccgcgt gcccgccgcg cgcacgtcct cgtctcccgg gcgctcggcc gtcagccgct
     9001 ccacctgctg tctcagctcc agcagccggc gcgagagggt ctcggcttcc gccgcggccc
     9061 gggtcagctg ctccccgagc cgcgcctcct ggctggccag ctcggactcg gcgcgcgcga
     9121 gctcggtctc acgcgagggc ggatgggcgg gggaggggga cggcgcgttc atctcggccg
     9181 tccattgtag cgcccctccc gggggccgac gagcccaccg cgtccctcct cccgcccggg
     9241 gcgtgtgggc gctctcgtac ccggggcgcg ggggctcagg cgccccggcg gagggctggc
     9301 tcgggccgcg caccctccag gcctcgccgg gcatgggcca gcagctcctc gcccatcgcg
     9361 tggaagaggg cgaaggtccg gtcggtcagg cctcgcgccc gctccacctg ctccgctgtc
     9421 agctccagcc cggcgatcgt ctcctccacg ttcccgctcc ccatcaggtg tcccgtctcg
     9481 agtccctcgt gggcctctcc gaagtagagc agccgcttgc ccgtcttcgc ctcgagctcg
     9541 cgggctacct gggtgaaccg gctgaagccc acgctcccgg cggcctcgac gctctccacg
     9601 atgaccagcc gcatcaccgg gctctccgcc gagacgaggg ccaccagccc gtagatgagc
     9661 tggcgcgcct tctggttgtg cgctccccac agctgctcga gcgctccggt gaagtccatg
     9721 ggggcgttca gctccaacgt cctcaggtcc ctcaggaaca tgccccagtg gtggtcgtcc
     9781 tcccgggtat gggtgttgat gagccgctgg atcggatcct ccgaggcctc gtcgcgcagg
     9841 acgtacttgt tgagatccgc gaaccccatg acgaatggcg ccatgcacgg ggcgaagccg
     9901 aagcgcagcc ggggctcgac gctcgcatcc ccgaggaagg tgaggaaggg agacctcgcc
     9961 agctccgcct tgtgctgctc gatgtgccgc agaacccgtc tcatggctgc gctccgctgt
    10021 aggcctcggt ggccaggtag aaggtggccc gccgcccgcc gccctgccgc cggaaggaga
    10081 cccactggat gagtcccacg ccgtcctcca gtggccggcg ggcgagcgcc cccaccgccc
    10141 gctccagcag gccgcgcgac tccgggtcca gcagggggcg gatgcgccgc agcgcgtcgg
    10201 cgtcgtggtc cgcgtagcag cggatgggga agtgcagcgt gacgctggag ggcctgccgg
    10261 gcgcatccga ggtgaaggac aggcaggtga gcgtcggccg ggccccggtg aagcggcccg
    10321 tggctccccg cagccgctgg cagaagtcgc gcgcctcgcc cgggacgtac tcgggggcga
    10381 gggccatgac gtcctcgagc tcctccgcca gggcctccgg gtgggcgagg tagaccttga
    10441 tacgggcggc gcggtgcgag gagagatcca acgagaagta gacgggccgg tccccgcttt
    10501 cccggcgcat ggcccgggtg aggacgtgcc acgcctcggc gcagccgagc cgctcgaggg
    10561 cctgccgcac cagggcctcg gcgccctcgg gaccccgggc gaaggggttg aggtacacct
    10621 tgagcgcggg ggcgccgccc ggcacgacac agacggcatg ccacagcccg aagcgggccc
    10681 gcgcatccac cggctcgaag agcgccttca cctgctcgaa gcgctccagg gacacgccga
    10741 gctcgtgccg cagccgctcg ttgagcgcca gggcggcctc ccagctggag cgcagcgtgg
    10801 tgggctggcc ctgggcctcc aacaggaagc gcacctcggg ctggcccgct tccatggcca
    10861 gggacagctc gaagggcgtg tggtcatcgg tgatgtccga gcgccaggcc ggcttgtctc
    10921 ccaggggcct ctgtccccag gcgccacaca tgagctcgaa ggtgcgccgc accgtccggg
    10981 tgtcttccgc gccgaaaccc accgcatggc acagcgcgtc gagccgctcg ctcccgaaag
    11041 accggagcga ttgccagggg atgggtgtgc tcaccgctgg agcccgctcg ttccataccc
    11101 gcatgaggat gtccgttctc gcgcaacggg gggggcgaca gctttgtcta ttttcgcgag
    11161 aaatgcaggt ttattgagct gtcagggtct tccagtgaac tcacggctat gtaagacatc
    11221 cgcggtgggg cgccggcggt gaggcaccgg cggtgcggtg tcagtccgcg cccttgatgc
    11281 aggcgatggg cttgaggcgc ttgtccacct tggccaggcc cgccatctcc acggtgtcca
    11341 gcacgtcgtc caggttcttg tagcagggcc cggactcgtc cagcggcgtc gtccgcgtgt
    11401 tgagcaggat gcccgcctcg gccatgcgcc ggtccgtctc ggactggttg agcacccgcc
    11461 gcgcctcgcc tcgcgacatc ctccgccccg agccgtggtt caccgagtag atggactgct
    11521 cggccccctc ctccgcgaag aggatggcgc tgcccgtctc catcgagccc ggaatgagga
    11581 tggggtgccc cgtcttctcc cactgcgtct tgcgcagcgc cgggtgcccg cccgggaagg
    11641 cgcgcgtcgc gcccttgcgc gccacgaact tccccgcctc cttctggatg aggttgtggg
    11701 agatctcgta atagatgtcc gccgtcccgc cgaacacctc ctcgagcgcc gcgcacaccg
    11761 cctcgccgat gatgagccgg ttggccaccg cgaagttggc cgccatgttg tgcaggttcc
    11821 agtactcgcg ccccagccgg ctctccgcgt ccagccagat gaagtcctcg ctgcgcttgc
    11881 tcagccccag cgccgcggcg ccctccacga agtagtgctt ggcgatgttc cacccgaagc
    11941 cccggctccc cgtgtgcaac atcacccaca cgcggccgtc ctcgtccacc tgcatctccg
    12001 tgaagtggtt gcctccaccg aggctcccca gctggtcgcg cttgtcgtag gcgcgctcgg
    12061 ggatgtccac ccggtcatcc tccaccggga tgaagtcgcg ctccgtggtg gacgcggtgc
    12121 ggcccagcgc cttggccccg tggcgcacca cctcggcgaa cgtgcgcgcg ttgacgctcc
    12181 gctgcttctg cacccgcgac gcccccacgc ccacggcgat gcgcttggtc acctcgttga
    12241 tccactcgcg gcgcttggcc ggatccgcca cgtcctcggc ggtgagcgtc gtcttgagct
    12301 gcaccatgcc gcagccgatg tcgtagccgg cggcggtggg cagcaggatg ccgtccgtct
    12361 ccaccaccgt gccgatgggc acgccgtagc ccaggtgaca gtccggcgtc accgccacgc
    12421 gcgtcacgcc cgggaaggac gccgcgttga ccacctgatc gaacacaccc tcttccagtc
    12481 ccggcagctc ggggccctgg ccccacagca gcttgtccga gaggaacagg tgcgcatcca
    12541 cgcgcatcgt cttcgtcttg ggcaggacga agtggccctc ggcgaccttc tccaaccttt
    12601 gtgtccagct catggccttt tccccctgga tgggttcaac cgctggcagc gacggacgct
    12661 tcctctggaa gctgacggac aaagcgggcg gccgagcttg cgaccggtca acggctgcgt
    12721 ctcgcggatg tcgtccacag tgtgcccgca gttgcccctt cactgaagaa ttcccattcc
    12781 tattcccgga gcttcaaggg ggtagggaga tggggattct gggtgcgttg ctggtggcgg
    12841 tcacggtgaa cgcggggccg gtggaggtga agacggcgcc ggtgttcaac ccggcggtgt
    12901 gcagcaagaa gcgcgtggac gcgtgcgggt gccaccatgt ctacggcgtg cgtcactgcc
    12961 accccaagcg caagagcgag cactgcgagg ccatggtgca ggccgagccc gccgagcaga
    13021 acgtctccac cgagcaggag ctcttctccc acgagccgga gcccgctacc gaggagacgg
    13081 cggactccgc caccctctaa ggggcatccg ccggtcgcgt ggcgtgccga ctggtccgac
    13141 aatcggacca gttgctcccc ctcgcgcccg gaacctcccc ccgacgccgt ctgccaggtg
    13201 ggcgggtaga ctcccgctcc atgcgcgtcc tcgtcgtcgc ttgcggcacc cgtggtgact
    13261 tccaacccat gctggcactc gccacggcgc tgcgggacgc cgggcacgag gtgctgctgg
    13321 gcgccacgcc caccttcgcc tccgaggccg cggccctcgg ggtgcccttc gcgcccgtgg
    13381 gcgtggactt ccagcggatg ctcgcggaac accgcgccca gctggaccat gacaatccgc
    13441 tggccgccat ccgcttgatg aatcgcgtca tgccggaggt gatccgcgcc gagtggcact
    13501 ccctccttcc cctgctcccg ggccagcagc tcgtcgtcgc tggaggcgcg gcgctctcgg
    13561 cgcgcagtgc cgtcgagtcc gtccgccttc cgttccgcta cgtcgcctat acgccccagc
    13621 tgctgccctc ggcgtggcat ccgcccttca tgattcccct cacccgcacg ccccgctggt
    13681 tcaaccggct cggctggtgg ggcatgggcg ccgtctatga caggctcctg ctgccggtcc
    13741 tcaacgagct gcgccgcggc cagggacttc ccgccctcac ggatgtcatc cgccaggcct
    13801 tcccctccga gcccggcatg gtcctgctgg ccgcggatcc ggagctggcc ccggcgccgc
    13861 cggacctctc cgtgcaccag gtgggcgcct tccacctcgc ggatccccgc ccgctgcccg
    13921 ccgaggccga gcgcttcctc gccgagggcg agccccccgt ctacatcggc ttcggcagca
    13981 tgccggacgc ggccccggag cggacctcgc tgctgctggc cgaggccgcc cggcgcgccg
    14041 gctgccgtgc cctgctgtcc tcgggctggg ccggcctggg tgaggggagt ctgggctcac
    14101 acgtccaggt ggtggggccg ctctcgcatg gggcgctctt cccccggctg gcgggcatcg
    14161 tccaccacgg cggcgcgggc accaccgccg cgtccacccg cgccggtgtc ccccagctcg
    14221 tcgttcccca catgttggat caattcatga acgcgcggta cgtgcacacc gcgggcatcg
    14281 gcctgtcgct ctcccgcaat cggctcgggg tggagcggct ggcgagcgcc ctcctccgcc
    14341 tgcgcgagga cccggcgctg cgtgcacgcg ccgcccacgt cggtgagcgg gtgcgtgcga
    14401 ggaattccct ggcggcggcc gtggccctgc tcgagcaggc cgcgcgggag gggctcactc
    14461 ctcggccgtc accgtcactt ccaacgtgaa ctcccgggac atcacccgct cgaggtcatc
    14521 cacctcgtag gccgtcagcg gcgtgcgcga ggagatgacc acccagcgcg tccccggcgc
    14581 cgccctcatg gcgagggtgt ttcccgacag cctgcggacc tcggccggag agggcagggg
    14641 cgccgcgggc gcggccggtg cggggggcag ggccagacgg cccgggacgt tcgcctgccg
    14701 cgtgtgcagc tccaccatgt cccgcttgtg ctcggggatg cgcgagggcg gcggcacgga
    14761 gggcggcacg tgcaccgcct ggcgcggcgc gttcgcgtgg ctcagccgct ccagcgcccg
    14821 ggccacctcg ttgtccctcg ggtcgagctc cagcgccacc ttcaacgccg cccgcgccct
    14881 cgcctcgcac cccagctgca gcaacagctc cgccgccgtc cggtacgagc tgatcgcctt
    14941 ctgcctgtct cccgcccgcc tccacgcctc ggcgtggcgc acgtacaggt ggggatccct
    15001 cggctccagc tccagcagct tcccgtaggt gcgcgcgcac tcggtgaact tccgtctcga
    15061 gtacaggtcc agcgcttgtt ccttcagctc ccgcacaccc atcactccac ccccaccacc
    15121 gccccgagta ccaccccgcc accgatcact cccgggcgtc acaagcatgg gccgtgccgg
    15181 agggacacgg cgctccacct cagggcaatt ccagcgcctc cgggttcaat ccgccttccc
    15241 agtccctgta agaaaggagg ggagccccgt tccaccctgt aaatcccggc cccccatgtc
    15301 ccagccctcg ccgctcgccc gcctgctcgt gccccacctg cgccccgagg cccgggggta
    15361 cgcggaagtg cccgcgctgg agacggtgct cgcggagctg ctcgcctccg cccacacggc
    15421 ctggccccgg gtgcggctcg aggacgccgt cttcctgcgc tacctcgccg agcgcctcgg
    15481 ccccacctcc gagcccgagc gcaccctgcg cgccctgccc gccgcggacc tcttcctcgc
    15541 ctgtgcctgc gtgcacgggg acgccgccgc ccaggccgcc ctggacgcgc actttctgcc
    15601 caaggtggcc gccgccgtcg cccgcgtgca cccgggcgcg gatgccgtct ccgaggtgtg
    15661 ccaggtgctg cgcgagaagc tcctcacctc cgaagggggc cagccgccgc gcctcgccag
    15721 ctacctgggc caggggccgc tcgccgcgtg gctgcgcgcc gccgccgtcc gcaccgccct
    15781 caacctgcgc cgctccgccc aacgccaggc ccgcgccgag gaggaggccc tcgccgaggc
    15841 cacgctgccc gggggcaccc accccgagct ggagcacctg cgccagcgcc accgggccga
    15901 cttccaggcc gccctcgccg aggccctcgc ggccctgccc tcgcgcgagc gcaccgtgct
    15961 gcgactccac ctcgtcgagg ggctgagcct ggagcgcatc ggcaccgtgt accgcaccca
    16021 caagtccacc gtgtcccggt ggctcgcccg cgcccgcgag gaggtgctcg cgggtacccg
    16081 ctcccggctc accgagcgcc tgcgcctgtc ctccggcgag ctgcacagcc tcctgcgcga
    16141 tgtgcccgtg cagctcgacc agagcctctc ctcgctgctc gccaccactg gggactccga
    16201 gggcccgtga gtttttttcg cgccgccgtg caacgcctcg cggccaccgg tgtcctccgg
    16261 gcagaacgca gggacattcc ggaggacacc atgaagaacg tgaagaagct gatgggcgtg
    16321 ctggcggtga cggcggtggc ggtgctcggc acggcggcgg gcgcggagca ggtggctccc
    16381 gcggcggccc agggcacccc cgcggccccc gcggagacga tccacgtcaa gaagggcgag
    16441 gtgtacacgc tggaggtgaa ggacctcgtg cgcatcgccg tgggggaccc ggagacggcc
    16501 ggcatctccg tggccgacaa gacggacaag aaggacgcca cgggcgtgcg catcgccggg
    16561 ctcaaggcgg gggagaccat cctgctgacg tggacgaagg acgggacgcg caaggcgtac
    16621 acgctcgtca tccggggctg atccacgccc ggtggcttcc cgtggcggcg cgtgcctgcg
    16681 acaatcccga cgcgatgccc ctggaatcga ggttgcgcgc gccggacggg tgcccggacg
    16741 agaatgtgct cgcgggtttc gcctcgggcg cgctggccca tgaggacacg ccgcgcctgg
    16801 agcaacacct ggacgggtgc gccgcgtgcc gggccctggt ggcggcggtg gccgccgagg
    16861 cctcacagcc cggggacagc ctcgccccca cgtgcctgga cacgggcacg cccacgctgc
    16921 ccatgcaccc cggagcgccc gcgctggagc cgggggcgca ggtgggccgc tacgtcgtcg
    16981 aggcgctgct cggcgagggc ggcatgggca tggtgtacgc ggcgagggat cccgcgctgg
    17041 ggcgcacggt ggcgctgaag ctgctgcgtc cgggcggggg aggggacgag ggccgggcgc
    17101 ggctggtgcg tgaggcccag gcgatggcgc ggctgtcaca ccccaacgtg ctgcccctct
    17161 tcgagctggg cacggagggc gacagcgtct tcctcgcgat ggagcgggtg gagggcccca
    17221 cgctggcggg ctggctgcgc gagcgggagc ggccctggcg cgaggtgctc gccctcttca
    17281 tgcgggcggg cgaggggctg gcggcggcgc accgggcggg actggtgcac cgggacttca
    17341 agccggccaa cgtgctggtg ggcgcggacg gacggccccg cgtcacggac ttcgggctgg
    17401 tgcgccacga ggccgggctg gacgaggcac tcccgggaga cgccgcggcc ggagacacgg
    17461 gggaggcgct cacccgggcg ggagcggcgc cggggacgcc cgcgtacatg tcccccgagc
    17521 aactcgcggg ccgcgaggtg gacgcgcgcg gagaccagtt cagcttctgc gtggcgctgc
    17581 atgaggcgct gtatggcctg cgccccttcg acgcgcgggc ccggggcgag gcgcgctgga
    17641 gccgggtgcc ggtgccgcga ggccctcgcc ttccgggcca cgtccgcgcc gcgctggagc
    17701 ggggcctgtc gctgtccgcg gaggcgcgct tcgcctccat ggaggcgctg ctgggggcgc
    17761 tcgctgcacc ctcggggccg cgctggcttc cggtggtgac ggtggtggcc gggctggggc
    17821 tggtgctcgc gggggcggac gtcgtggtgt ggcggacgcg ggcgccggag gcggtgcccg
    17881 cccaggaggc catgcccgtg gcgttgatgc cgggcacgcc cgtggagctc gagattcccg
    17941 ggatggtgcg cgtggcggtg ggcaccccgg acgtggtgga ggtgaaggtg ctggaggcgg
    18001 acaaggtcca actcctcccc ctcgcgacgg gcaccaccac gatgctggtg tggacgcggg
    18061 acggtacccg ccggacgtac aacgtgtccg tgggtccata ctgagcgggg cccccccttt
    18121 acgagcgcat gggcgcgggg actatcgtgg gagtccactc gtcgcggagg gctgcgcgtt
    18181 gcgctccatc aatcccctgg cgtcctggcg gtggtgtctc ctggcggtcc tcgcggtggg
    18241 ctgcgcgcac tcgagcacgg gcccggcggc cgtgactgcg gagccggccc ctcgtgccca
    18301 agccgctccc gtggacgcca acctcgccga ggcccgggcg ctcacggacc agatgttcgg
    18361 tcccgaggcg caggccacgc agcgcaagca gcggaaggtg cgccggctga tggtgctcac
    18421 gggcgcggag gacacgggcc ggcagatgct ggagatgatg acgagccact tcgagcagtc
    18481 ctcgagcatc ccaccgggct tcatggagaa gttccgcgag gcggcgcagc aggagtccat
    18541 cgtggacctg ctggtgccgg tgtacatgaa gcacttctcc gaggaggacc tggacgcggc
    18601 catcaccttc cacgagtccc cggcgggcaa gcgcttcctc gcggcccagc cgcgggtgtt
    18661 gcaggaggcg aaggaggtgg gcgagcagtg gggcgtgcgg ctcgcggaga aggccctgcg
    18721 ggcgctggtg aaggaggagt cggagcggaa gcccacgccc gcgcgtcacg agggacagga
    18781 gctgtaacgg cgcgtcactg gtgctgggct ctcttcgaag gggccgtgtt ggcgaggttc
    18841 tgggtcttcc agaggcgctc ggcggcctcc cgctccaccc tcagccgctc tccgcgttcg
    18901 cggacatcct cctcccgggc gaacagggcc ttcagctcca ggtagcgctt ctcgtagtca
    18961 tccttggcgc tgtactggta gcggcgctcc tggttgttca tgcgtatctt gtctccgccc
    19021 atcatcttga agcagccatt gaagacgggt ttgcccgtgc gcaacacgcc attgggcatg
    19081 cggtagcggc tgtccgaggt gtaggaggag aagtccgcct ggtagtactg gtggtactcg
    19141 atgaagaagc ggggcatgtc ctcgtaggca tacccaagcg acagcgccat gtcgtgcagc
    19201 tgttggaagg ccgtgccgct gctcgtcttt cccttgaagt agtcgccgaa ggggtccgcg
    19261 tcgacgaggc tgatggcgat cttccactcg gcgggtgtcg tgcccagcac atagcagtgc
    19321 ttgcgcagct catccaccgt gagcacgtgc tcgccctcct tgccgtactg cagcttcgag
    19381 ttcaccttct ccatgtcgtg gaacaggatc gtcttggcga tcagcttcca cgggatgagc
    19441 cgcgcgtcgt ccttctcccc ctcgacgagc ttcaggtact ggcacagcac catctgcgcg
    19501 tgcacgtaga aggagtagtc ctcgctcttg gcggagatct tgttgtagcg ctgctggagc
    19561 tgggggtggc gcgagatgag gtggttgatg agggcctggg gcgtctggcg cgcgtcgagc
    19621 atctggtcca gctgcctgcc cgtctcctcc agccgcttcc tgtcgctggc ggccgacgtc
    19681 tgccatttca ggaagtcatg caccaccggg gctcccgccc ggacgttctc gtccttgttg
    19741 atgcgctcgt agtcctcggc gatcacatgg gcgatcatcg cctggctcgc ccagggggtg
    19801 acgatcgtgc gcaggaagac ctcggcctgc tccgtgtcca agggatcgat gtcgtggtcc
    19861 gtcaggaatt tgtcgagccg cgtcttgcgc gcgtagtagg ggatgttcgc gtcccggtcc
    19921 gcgagcaggg ggctgcgggt gcgctcatgg ggctgcttct tcgagtcgct ccaggtggcc
    19981 aggtacaggc tcaacgtgtt ggccagggtg aggaacttct tcttgtcggt gaactccccc
    20041 ttcgtcaccc agatgtccag gctcttcagc ttctgctcgg ggatgtccag gcgcgcccac
    20101 agctcgcgca cgtcgcgcac ctctccggcc cggtcggcct ggggcaggtc gtggggccgg
    20161 taggtgtagg tgatcaagct gtaggggagg gcgtgcgccg cgagctgctt caagccgtct
    20221 tcctggaagc cgtattggtt cggctcgtag tgccggtcga cgttgaagct gggcgccgtc
    20281 ttgaattgct tgaggaccgc ctcggggacg gccttcttca cgatggtgtt gaagcggtcg
    20341 agcgggaaca ggtacgtgcg gatgacgggg ttgttgagcg cggcgtgctg cgcctgcttg
    20401 gtggcgtacc cgtcctgggt ggacttcgtc gcctggagga gcgcgagctt gcgcagcccg
    20461 agcgcgccgc tcttcggtgc ggtcggggtc gtgggcgtgg gcctccgctc cagggacggc
    20521 tgtgagcccc agaggctctg gaggtcgcgc gtgtgctggg cgatcagcgt gggcagctgc
    20581 gcgcgcttct ccggatgggt gttcttctgg ctgtaggcct ccgcgagcgt gcggtgctcg
    20641 gcgatgtact tctcggccca cttgagggcg cgcagcggac gtccaccgcc cacccagagc
    20701 atgcggttct tgcccgaggt gatgaagagc tgtccggtgg cggggtcctg ctgcacgtcc
    20761 ttgaagtcgc tcgtggcctg gcccgtgcgc ggatccggat tcgtcatcac ggccgccgtg
    20821 gggacggaca ggtagaggcg gacgtacggc tttccctcca ccatctcgag ctccaggtcc
    20881 gcccggtgga tggcctccgc cttgtcgtca tggcggctgg gccccaggtg gtactcgccc
    20941 ggcacggcga gccgtggttg ctgggcctcg cgggcgcgct cctccaggtt cgtcggcgcg
    21001 cgcagctgca cggccaacac gtccttcacc acctggttgg gcaccttgcc gggcgcgggg
    21061 aggcggaccg agta
//
