LOCUS       NZ_CP011509            21035 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Archangium gephyra strain DSM 2261 chromosome, complete genome.
ACCESSION   NZ_CP011509
VERSION     NZ_CP011509.1
KEYWORDS    RefSeq.
SOURCE      Archangium gephyra
  ORGANISM  Archangium gephyra
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Archangium.
REFERENCE   1  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Genome assembly of Archangium gephyra DSM 2261
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12489432)
  AUTHORS   Sharma,G. and Subramanian,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) Protein Science and Engineering, Institute
            of Microbial Technology, Sec-39 A, Chandigarh, Chandigarh 160036,
            India
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: HGAP Pipeline v. SMRT v2.3.0
            Coverage                          :: 79.3
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001027285.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:37:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,001
            CDSs (total)                      :: 9,898
            Genes (coding)                    :: 9,822
            CDSs (with protein)               :: 9,822
            Genes (RNA)                       :: 103
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 28 of 76
            Pseudo Genes (incomplete)         :: 45 of 76
            Pseudo Genes (internal stop)      :: 6 of 76
            Pseudo Genes (multiple problems)  :: 3 of 76
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 574412
            Orig. end                         :: 595447
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21035
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21035
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21035
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11035](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11035
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(11..25)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     misc_feature    156..169
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(180..196)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.56"
                     /tool="antismash"
     misc_feature    complement(564..578)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(1733..1746)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            complement(2603..4423)
                     /locus_tag="AA314_RS02550"
                     /old_locus_tag="AA314_00528"
     CDS             complement(2603..4423)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373961.1"
                     /locus_tag="AA314_RS02550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00528"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_047854141.1"
                     /sec_met_domain="Pkinase (E-value: 3.8e-35, bitscore:
                     120.7, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPVRGAPQPLNSAIPDPHQGERIGRYQVLTQLSVGGMAELFLG
                     FTSGPGGFRKYVALKRVLPDARGDEQFEKMFLDEARITAALNHPNIGQVFELGQDAEGL
                     FLAMEFIAGQNLNQVAHVCRRRGKVLPAGFSLAVVRDVCLALHYAHAFTTPGGKPSPVI
                     HRDVSQKNVMVTYDGVVKLLDFGIAKARDGVVRTQVGMVKGTTGYMSPEQVRGEPLDGR
                     SDLFAAGVMLHELLTGERLFSGETERQEMEMILEAPIPVPGAKVPTLPPEVSTVVLKAL
                     ARKREDRYANGREMAKALEAAAGGLLLDSEQRAAFMLENFGDRMEATRRLLESVEQVKE
                     PADSETARMPEGREEPGSVSTEPSSTQPGGRAEKTEETPRAEPVEARPARGPGARRTET
                     GEAPATGVHTTGRRVTREAPVAAREARTTEQPARGGTGRFWAAILALLVVGGSAGYGAV
                     KLVAAMKAQEAEGTPIPMPLADMSPMTPIEPPGQKKAEPDPAAQAAAPVQAPEQTQETP
                     EEPAKKDGDGEPVRNVKQGALTLVVLPEAEVFLNGRSLGKTPLIKTPVPVGRHLLRIKG
                     ADGKRRQLSVPIRVGKTTQFKLKLTDIPER"
     misc_feature    4633..4646
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.6"
                     /tool="antismash"
     gene            complement(4763..5050)
                     /locus_tag="AA314_RS02555"
                     /old_locus_tag="AA314_00529"
     CDS             complement(4763..5050)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637814.1"
                     /locus_tag="AA314_RS02555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00529"
                     /product="hypothetical protein"
                     /protein_id="WP_047854142.1"
                     /transl_table=11
                     /translation="MASIESAISEQLAQAFTVCIPYELQPGMDQLPSDTRHTLLGELFR
                     LAVQAWQERCLLPRHGPVNLEFLLAGCDVGIELDAPRARLTLVSLIRGRS"
     gene            5250..7433
                     /locus_tag="AA314_RS02560"
                     /old_locus_tag="AA314_00530"
     CDS             5250..7433
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015345644.1"
                     /locus_tag="AA314_RS02560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00530"
                     /product="hypothetical protein"
                     /protein_id="WP_047854143.1"
                     /transl_table=11
                     /translation="MARKTRMDGWGRVLAAMLLCGLLGACREEKPPLVGSSSQVRFSQE
                     ALAFPATYVGSTREASVRLVSAGRSGVRMAWNGVQGPFSLQGLPSEVRPSEEATVTVRF
                     APGAEGTFSATLVGTDEAGRTVTLGLSGEARLAPPCPMPAACHRFTFDTEREECVEEVL
                     EDGTGCDPGNACVLDAVCQQGRCKGRERVCDDGNACTTDVCSPLDGCQVVPAPPCPGDG
                     ACQEGWCDPARGCQLKPARNGTFCGEARGCDLADVCVEGTCVKRDPPDHFVCAPASPCQ
                     GEGRCRGSVCERPAARPLVPDWTYDAAAQGQKLHDLLVGPEGDVTLAGFFEKPVLDAAG
                     DAPMQAQVTGRRCMVWNERLLCMDLPQQGKVSLMERATAAPRWSFDLGRARPDIAQKSS
                     TLFMARLAVMAPDRLAALFEGYPAGQDAKTLCRLYYLVVLDAAGGLVSAQLLEDPLLSE
                     CNHPHPFGLASDPAGDLYVTFSPTVNSGAPLRAGAPTLVMAFSSDGVPRWRRTLPFPGG
                     ELGLVRGLLMPEGGTEPLRTSDGEPVGTLSLKLGRAVATREVLVPSPAGATVNPDVAPV
                     ASPRLEGYAVPGLEPAWTYRLPAGASFVSKELRLGTWPEGGVKRTMVLGFATEGRRPVL
                     VGVRAGDGSEAFRCELGYSPRTIPQLFELGPGSLTMMDGATSCGECDPPFSESRARFQR
                     FTLPGLEPAEAPWPGTFGGPGHDHHEDPVRAAP"
     misc_feature    complement(5254..5268)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            complement(7458..8573)
                     /locus_tag="AA314_RS02565"
                     /old_locus_tag="AA314_00531"
     CDS             complement(7458..8573)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014691.4"
                     /locus_tag="AA314_RS02565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00531"
                     /product="Fic family protein"
                     /protein_id="WP_047854144.1"
                     /transl_table=11
                     /translation="MSLWEKARWPGFTWGDGGVVGPLAEARYKQGRLLGSMVRLGFELR
                     LEAQVHTVTEDVLKSSELEGELLDRESVRSSVARRLGVPDAALSGSDPDRKTEEVVAMM
                     LDATGNFAAPLTKERLVGWHAALFPTGYSGFHRIKVGGWREDSEGPMQVVSGPVGRTKI
                     HYEAPPAERLDAEMERFLDWFNAPPLLDGLLRAALAHLWFVTVHPFDDGNGRIARAITD
                     MALAQLEQSSQRFYSVSSQIRLERSAYYDTLERTQKGSLDVTVWLVWFLECYARAIDAA
                     EATCAGVLRKADFWQHYAREPFSPRQKAVMNRLLDGFEGKLTAKKWAALGKCSVDTAQR
                     ELTDLVARGILVKNPGGSKNTSYALAFEQPR"
     misc_feature    complement(8730..8742)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            8738..9385
                     /locus_tag="AA314_RS02570"
                     /old_locus_tag="AA314_00532"
     CDS             8738..9385
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS02570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_00532"
                     /product="hypothetical protein"
                     /protein_id="WP_053066024.1"
                     /transl_table=11
                     /translation="MTQPPFPRRGLLAPLAAVLVWSLGPLAGAQVTVSVREPLLLQVGE
                     RRFQLQVGSESISGGGLELRRVQGGLRGTLKGQPVALKWNEDGAITGRAAGASVQLDAI
                     SRAPQPGLILRGWFGADPAELTLTPTGISGSVGGCDYSLPMAGNRYTGWRTCDATRGPP
                     APVTLRIPDNLVPLGLTEEGALLALLLSDEALPPAPSTGETPGVGGSGTPSP"
     gene            9412..9855
                     /locus_tag="AA314_RS02575"
                     /old_locus_tag="AA314_00533"
     CDS             9412..9855
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA314_RS02575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AA314_00533"
                     /product="hypothetical protein"
                     /protein_id="WP_047854145.1"
                     /transl_table=11
                     /translation="MARKALAWLAVLGLVAPAGAQEVLGGDDLPDNMDEFRRTPLTDDV
                     PITDEEAGVGGSGTAGTGDGARQGELHGEVVSVRGAQLWLREGGAVFPIELTQETRFTP
                     DRSQALQPGQEVRARFTLEGDGYVVNALEPTGQVPVEKQPGER"
     gene            10001..11035
                     /locus_tag="AA314_RS02580"
                     /old_locus_tag="AA314_00534"
     CDS             10001..11035
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014394622.1"
                     /locus_tag="AA314_RS02580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00534"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_047854146.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.2e-40,
                     bitscore: 137.9, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-18, bitscore:
                     66.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTEPAAIAFCREVLPAVSRTFALNIPVLPRPLDTAVMVAYLLCR
                     IADTLEDEAHGPASEVLLAELARLSTLPAGWEADARRFSEEGARVLRTQAPEAEVRLVA
                     GTARVLEALALHAVPVREHVASCVATMTKGMGKMGDKGRASGGGLGLASLEETLEYCYY
                     VAGTVGEMLTRLFQWYSPAIAERAAALEPRAVAFGNALQLTNILKDVREDLERGSCWLP
                     KTLLAEHGLTPEALLEPGNRGEAMKAHGQMVAVAHRELRKAFEYVMALPGQERGIRLFC
                     LWPLFLAVMTLRKLYGNAAVLERRAVKVSRRTVKWVVASTRLLVGQDAALKLMFSTLTA
                     PLPR"
     gene            complement(11041..12021)
                     /locus_tag="AA314_RS02585"
                     /old_locus_tag="AA314_00535"
     CDS             complement(11041..12021)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013375828.1"
                     /locus_tag="AA314_RS02585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00535"
                     /product="aldo/keto reductase"
                     /protein_id="WP_047854147.1"
                     /transl_table=11
                     /translation="MPRTLGASGPTVSPLGLGLAALGRPGYITLGHGEDLRGDRSVEAL
                     ERQAHEVLDAAYLAGLRYFDAARSYGRAEAFLASWLKARGMRPEDVVAGSKWGYTYTAA
                     WRVDAERHEVKDHSLPTLRRQWGESQTLLGPWLRLYQIHSATFESGVLEDTGVREELGR
                     LRDSGVRVGLTLSGPRQAEVLRRALELQVGGSPLFSCVQATWNLLESSAGPVLAEAHAA
                     GWGVIIKEAVANGRLTARNEDPALRPLREVAGALGATVDAVAIAAVLAQPWVSVVLSGA
                     TTVEQLQSNLRALEVKLGDEARETLRRLAEPPETYWAKRSALPWN"
     misc_feature    12160..12174
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.7"
                     /tool="antismash"
     gene            12169..12675
                     /gene="msrB"
                     /locus_tag="AA314_RS02590"
                     /old_locus_tag="AA314_00536"
     CDS             12169..12675
                     /EC_number="1.8.4.12"
                     /GO_function="GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013375829.1"
                     /locus_tag="AA314_RS02590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00536"
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="WP_063796847.1"
                     /transl_table=11
                     /translation="MSQERRSRRGVLVLLPLLLLGGLAAGEPEPGHSHEEGTKVYAVQK
                     TDAEWKQQLTPEQYKVLRKQGTERAFTGKYWDLKAAGTYHCAACGQPLFSSETKFDSGT
                     GWPSFWQPLPGAVDTHEDSSWLMVRTEVVCSRCGSHLGHVFDDGPEPTGLRYCMNSVSL
                     DFRPK"
     gene            complement(12679..13278)
                     /locus_tag="AA314_RS02595"
                     /old_locus_tag="AA314_00537"
     CDS             complement(12679..13278)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630990.1"
                     /locus_tag="AA314_RS02595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00537"
                     /product="DUF938 domain-containing protein"
                     /protein_id="WP_047854148.1"
                     /transl_table=11
                     /translation="MKQHAPSAERNREPLLAVLRELLPSQGTVLELASGTGQHAVFFAR
                     AFPRLTWQPTDADALARSSIDAWRREEGLPNVREPLALDARASPWPVESADALVCINMI
                     HISPWESCQGLMRGAARVLPPGGPLILYGAYFIEGRPTAPSNLAFDASLRERNPAWGVR
                     ELGAVTAEARAHGLELDRVIDMPSNNFTVVFRKRGG"
     gene            13447..14913
                     /locus_tag="AA314_RS02600"
                     /old_locus_tag="AA314_00538"
     CDS             13447..14913
                     /GO_function="GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /GO_function="GO:0030551 - cyclic nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015348795.1"
                     /locus_tag="AA314_RS02600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00538"
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="WP_047854149.1"
                     /transl_table=11
                     /translation="MLPFLQSHLSLIAGVLFTLLVIGVRAASADAQFRKELGRALGFLM
                     TFLVLRVVEGQFGELLHSRVLPLLRVAWMLAFAFGGIRAAMSLGVLTVTRLGIRTPPPK
                     ILRDVVEISLYVIAVVPILRAELAIDLTSLLATSAIVSVVLGLAMQDTLGNLFAGLSLQ
                     LERPYDVGDWVTIKEITGRVVQVAWRATRLETSRKEIITLPNNICSKEAVKNYSRGGQP
                     VGVDLSFHGPYDRAPNEVKEAVLEVLEQVPLVLSAPPPMCRTVGFEELGIRYQVRYYVE
                     DFSNADAVMAEFYTRIWYRFRREGIEVPAQRKLNMSLGAPGSEFSEELVADMLRRVDLF
                     KVLREEERAKLRREMVPRRFARGEHVIEQGEKGNTFYLVGRGELSVRTGGVEVSRLSRG
                     NYFGEMSLLTGEPRTATVVALTDVVLLELGRPVFARLFEEHPELAPKLSGMLSHRRMQL
                     EAAMTASGETLPITEEVDILGRLKSIFRLD"
     gene            complement(15007..15705)
                     /locus_tag="AA314_RS02605"
                     /old_locus_tag="AA314_00539"
     CDS             complement(15007..15705)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022441.4"
                     /locus_tag="AA314_RS02605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00539"
                     /product="head GIN domain-containing protein"
                     /protein_id="WP_047854150.1"
                     /transl_table=11
                     /translation="MQLRSLLLPVALLASTPVFAQDAAKAGQIEVPDFRGVAVGYGIRA
                     EVKPGPKSVRLEGSKEDVARVKLEVKDGVLTTQVEKGSSYFGKGLKNVRLYVTSPRVES
                     VAASGGADVDAEATRVDSFDVAASGGSEVDVIKVDAKNLQVAASGGSELRLEGSTGELT
                     VIGSGGSVIEADKLRLESLQVTASGGTRVEASPERSIQGNLSGGSTVKAGKKPASVQVN
                     SSGGSQVQYE"
     gene            complement(15797..18946)
                     /locus_tag="AA314_RS02610"
                     /old_locus_tag="AA314_00540"
     CDS             complement(15797..18946)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013936805.1"
                     /locus_tag="AA314_RS02610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA314_00540"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_063796848.1"
                     /sec_met_domain="Pkinase (E-value: 1.6e-36, bitscore:
                     125.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGSKLPFAPGDVRGRQMGNYEVLCRLSTGGMAEIFLASKRGLAG
                     FQKPVVLKKILPDIQGQEEFVQMFLDEAKVTAAFNHPHIAQVFDLDVDDGELFLAMEFV
                     PGATLLEVARACRAANEPMPMGLGLAAVRDTALALHYAHTFTDALGQPSPVIHRDVAEK
                     NIMVTYEGVTKLLDFGIAKSLSSVSRTAAGMVKGTSGYMSPEQILGEPLDARSDLFSLG
                     VVLHECLTGMRLFPGKAPMAVINAVLKGPIPEPSRANKAIPPELDAIVLKALARKRADR
                     YATTLEFARALERAVGPLIWLPEQSSELLRRLFAERREQTRQLLASGRAGVDSTGVVKL
                     AQLFPDKEASTPPTAAPATPSSPGVAAPVGPRTPTPHAPRLPTISAPQLPPPGPARPDQ
                     TELVPYPVVAKPPGSLPGDRRTASSSQFPVSPPPPPEETGVQPPAPSTSRARPPRVQVD
                     PSTLPSLPVLTEPPRAPLATPARAQVDPSTLPSLPVLTEPPRPVRAPTPVEQGRAASPE
                     QTRAEPRPRSSLGRSDAVPALPETREPGLKTAVIRPQRSTPTGEQPAASDSDATQPRYD
                     STRAARRSTLEHLDAVTLPTGSPTFPPGPPAPPLPSESPTVPGRRAPLARTPEPEDEEP
                     ELLTMPLLQAPAAPTRPPAGVPEDDEGPELLTAPFLRPPSPASRPVEPEDDEEPELRTV
                     PFLSPPAEASRSFPGPRSDEPDEEDLTPAHPQPISRRHTPVKREEDASEEATVSSGASE
                     APSRRGVLWAVLLLLLLVGGLAALVVLRLDGGLVSSQLFPPPPEAAIELPAPEAPLAVQ
                     AAPTPPGDSAPAPEAAAASATPETPGAAALEPAAATPEAGAPPDAAPPTDALAAAPTTD
                     AAAGTPPAPPEVKNEALPATGEPAEASPQAKAPEAEAPEAEAPDTEALETTQPAKRGKV
                     APSRRTAPRTASNVETSPEQVTTADEADRAWQALERERTGAAEPSADKGFLTLATEPYA
                     KVYLGNRVLGETPLFRVPFAPGKHTLRLVAPRFKPLKLQVEIKAGEVTSIRAPLEKLGR
                     E"
     misc_feature    complement(19315..19329)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.66"
                     /tool="antismash"
     misc_feature    complement(19355..19370)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(19630..19644)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.52"
                     /tool="antismash"
ORIGIN
        1 gggtttcgac atcgacacgg cgaatgccca ggccttccgg cgggccatgc acatgctctg
       61 tgacttcgcg gagcgcgcgc cctcgtcgat catcgtcatc agctgcctgc acaacttctg
      121 gaatggtctg cgcggccagc tcaccaagtc cctgctggac cggatcgaga gggatcccga
      181 tctcatcaaa ttgcagcacg tgcgcacggc cgaggaggcg cggctgatca ccgagcgccg
      241 gctggagcac ctctactccg tggaggacgc tcccttcgat ccggcggagc ccacctatcc
      301 cttcccgcac gagcgcttcg atctgctcgc gggcaagagc acgcgcgagg tgctcgatgc
      361 gtgccgccgc tggcgtgagc aggccatccg ccagggcgcg ctgcccgacc gcttcccgct
      421 ggagagcgat caagtccagg aggactcgca ctccaagggc aaggaggacg aggagaagaa
      481 gaagcagacg ctggagctgg accaggtgtg gaacgacttc cgctcctcgc agtccacgcc
      541 gccgcccgag gaggatccgc agctggccga gctgctcgtc tgggcgctgc gggcctgcgc
      601 ggacgaggtg gagaccgggc agcacttcga ggcgcgcctg acgggcgcct ccatccaggt
      661 ggaggtgact ccgggggagc agaagctgca cgtggccctg tgcaaccggg ggacccagcg
      721 gggagcgctc gccaatcaga tcgaacaggc gcggaaggag tcgcggggcc gcacgcccgt
      781 ggtcgtccgc accagcgatt tcccgagcaa tcccaagagc accacggccg agcagctcgg
      841 caagctcttg agcaagggag gccgccgcgc ggtgctggag gacagcgaca gccgcaccct
      901 gctcgccctg cgcgagttcc gtcagcagca cgagtcgcgt cccgacttcg ccgcgtggct
      961 gcgctccgcc cggcccctca cccagctcaa gtccctgcgc gacatcctcg ggttggatca
     1021 gccgcgctcc tcgccgggct ccacgccctc cggttcccag aatgcgcccg ccgagacacc
     1081 tcccggtggg acgcgggccg tgacgtccgc gcccgtcgcc tcggcgacgc aagccacccg
     1141 gaccgagccc aaggctcctc ccgcggcgaa gaccgtggtg cagacgcctc cgcgcaagcg
     1201 cgagcccatc cgcatcggtg agacggacag cctgctgagg gagcccgtgc tcatcgcacc
     1261 cgacgagctg acccggcact gcgcgttcct gggaggctcc ggcagcggca agacgacgct
     1321 ggcgctcaac gtggtggagc agctgctcct gcaaggcatt ccagccatcc tggtggaccg
     1381 gaagggagac ctcgcgggct atgcctccga gtccttctgg acgcgcccca tcgaggacgc
     1441 acgccgcgcc gagcgccgga ccctgttgaa cgagcggctc gacgtggccc tcttcacccc
     1501 tggccatccc cacggccgtc ccctggggat ccccatcgtt ccggagggac tcgccgcgct
     1561 ctcggactac gagcggcagc aggccacgcg ccatgccgcc gaggcccttg cgggcatgct
     1621 ggactaccgg cagaaccctc gggacaagtc ctgcaggacc ttgctgtcgc aggcgattga
     1681 tcagctcgtc cagctcaggc ccgagggggt gacgctggag aagctcgtga agttcatcgg
     1741 cgacaaggat cccatcctgg tgagcgccgc gggccggctg gacacgaagc tcttcgacaa
     1801 gctcgccgat gacctggacc ggctgcgcat cgacgcgaag catctcatgg gcagcgaggc
     1861 cgagcggctc gacatggatc tgctgtttgg ccggggtgtc cacgcgaagc ccggcaggac
     1921 gcgcctgagc atcatcagca ccaagttcct cggtgacacc aacagcgtgc tcttctgggt
     1981 gtcgcagctg ctcatcgaga cgacgcggtg gctcaaccgc aaccccgcca cggcgctgca
     2041 ggccgtcctc atgttcgacg aggcggacat gtacctgccg gcgatgcgcc agccctccac
     2101 gaagcagccc atggagaacc tgctcaagcg cgcgcgctcg gcgggcgtgg ggctgatgct
     2161 cgccacgcag agcccgggtg acttcgacta caagtgccgc gacaccatcc gctcctggtt
     2221 catcggccgg gtgaaggaga aggtgtcact ggacaagatg aagcccatgc tcagcgaggc
     2281 gcgggtggac gccacgaaga ttcccggcca gtccattggc gaattccact tcgcgcggga
     2341 tggccgggtg gatcgtgtga agaccgagcc ctcggcgatg gcgaccgagc agctctcgga
     2401 cgacgagctg ttgcagctcg ccgcgaggac ggcgccgaag ggcacggacc cgcacacgga
     2461 ctcctgaccc aaggggaagg ttgaaacctt gtcagggggg cactccgctc ccctgacaaa
     2521 aaggaggggt gcccacccga gcgctcgtca ggtcaccgcc gcaggagctc gtcaggccgt
     2581 agtggagcag gccgggggag cctcagcgct cggggatgtc cgtcagcttg agcttgaact
     2641 gcgtcgtctt gcccacccgg atggggaccg acagctgccg ccgcttccca tccgctccct
     2701 tgatgcgcag caggtgtctg cccaccggca ccggcgtctt gatgagcggc gtcttcccca
     2761 gcgagcgccc gttcaggaac acctcggcct ccggcaggac gaccagcgtc agcgcgccct
     2821 gcttcacgtt gcgcaccggc tcgccgtcac cgtccttctt cgccggctcc tccggtgtct
     2881 cctgcgtctg ctccggagcc tgcaccggcg cggccgcctg ggcggcgggg tccggctccg
     2941 ccttcttctg ccccggcggc tcgatgggcg tcatcggtga catgtccgcc aggggcatgg
     3001 gaatgggcgt cccctccgcc tcctgggcct tcatcgccgc caccagcttc accgcgccgt
     3061 agcccgcgct ccctcccacc accagcagcg cgaggatcgc cgcccagaac ctccccgttc
     3121 ctccccgcgc cggctgctcc gtcgtccggg cctccctcgc cgccacgggc gcctcccgcg
     3181 tcacccgcct ccccgtggtg tgcacccccg tcgccggagc ctcgcccgtc tccgtcctcc
     3241 gcgccccagg cccacgcgcc ggcctcgcct ccaccggctc cgcccgcggc gtctcctccg
     3301 tcttctccgc acgcccaccc ggctgcgtgg agctcggctc cgtggacacg ctccccggct
     3361 cctcgcggcc ttccggcatc cgcgccgtct ccgagtccgc cggctccttc acctgctcga
     3421 cgctctccag cagccggcgc gtcgcctcca tccgatcccc gaagttctcg agcatgaagg
     3481 ccgcgcgctg ctccgagtcc agcagcaggc cgcccgccgc ggcctccagg gccttcgcca
     3541 tctcccggcc gttcgcgtag cgatcctccc gtttgcgcgc cagcgccttg agcaccaccg
     3601 tggacacctc cggtggcagc gtgggcacct tcgcccccgg caccggaatg ggcgcctcca
     3661 ggatcatctc catctcctgg cgctccgtct cccccgagaa gaggcgctcg ccggtgagca
     3721 gctcgtgcag catcaccccg gcggcgaaca agtcactgcg cccatccagc ggctcgcccc
     3781 gcacctgctc cggggacatg tacccggtgg tgcccttcac catgcccacc tgggtgcgca
     3841 ccacgccgtc gcgcgccttg gcgatgccga agtccagcag cttcaccacc ccgtcgtacg
     3901 tcaccatcac gttcttctgg gacacgtccc ggtggatgac aggggagggt ttgcctccgg
     3961 gcgtggtgaa ggcatgggcg tagtgcagcg ccaggcacac gtcgcgcacc accgccaggc
     4021 tgaagcccgc cggcagcacc ttgccccggc gccggcacac gtgcgccacc tggttgaggt
     4081 tctgccccgc gatgaactcc atcgccagga agaggccctc ggcgtcctgg cccagctcga
     4141 acacctggcc gatgttcggg tggttgagcg ccgcggtgat gcgtgcttca tccaggaaca
     4201 tcttctcgaa ctgctcgtcc ccgcgtgcgt ccggcagcac ccgtttgagc gccacgtact
     4261 tgcggaaccc gcccggcccc gaggtgaagc ccaggaacag ctcggccatg ccacccaccg
     4321 acagctgggt gagcacctgg tatcttccaa tgcgctcgcc ctggtgcgga tcggggatgg
     4381 cggaattcag tggctggggg gccccccgga ccggtgcgga catgggccga accatagccc
     4441 accgaccctg tggacggcct gtggatggcc gggccgcctc tgtggataac cccggggatg
     4501 atccacaccc tgtggatggc cggggataag cgccaacttc cccacatgta gcagcttctg
     4561 aattcctcag tggttccaaa gggttgctga cttttccaca agcccacaga ccctgctgtt
     4621 acccctgatc aatataaata ctctctcact cagtacagaa acagagggcc ctggggacaa
     4681 gtggaactgt ggagaacggc ccccggctcc cggcctccgg acaacggctc cccggaagcg
     4741 gccaggcccc tgggcaggcc cctcaggagc ggccgcggat gagcgagacg agggtgaggc
     4801 gggcgcgggg tgcgtccagc tcgatgccca cgtcgcagcc ggccaggagg aactccaggt
     4861 tgacggggcc gtggcggggc agcaggcagc gctcctgcca ggcctggacg gcgaggcgga
     4921 agagctcccc cagcagggtg tgccgggtgt cgctcggcag ctggtccatc ccaggctgga
     4981 gctcgtacgg gatgcagacc gtgaaggcct gcgccaattg ctcggaaatg gcggattcga
     5041 tggaagccat gattggggaa cttgccagaa gcataccggg gggagagccc gtgattccgg
     5101 gggtttggag gggcttcccc ccgggtggac cgtagaaacg ccagtgcgtc cgagggtggg
     5161 ctggtgaacg ggacggaggc ggaggtgggg cgggccccct cgtgcctccg aggagcgagg
     5221 gctatagccg tgggagcggg gactcacgca tggcgcgcaa aacgagaatg gacggctggg
     5281 ggcgggtgct ggcggcgatg ctgctgtgcg ggctgctggg ggcctgccgt gaggagaagc
     5341 cgccgctggt ggggtcctcc agccaggtgc gcttctcgca ggaggcgctg gcctttccgg
     5401 ccacgtacgt ggggagcacg cgggaggcct cggtgcggtt ggtgagcgcg ggccgctccg
     5461 gggtgaggat ggcgtggaac ggggtgcagg ggcccttctc cctccagggg ctgccctcgg
     5521 aggtgaggcc ctcggaggag gccacggtga cggtgcgctt cgctcccggc gccgagggga
     5581 cgttctcggc cacgctggtg ggcacggacg aggcgggccg cacggtgacg ctggggctgt
     5641 cgggggaggc gcggctggcc cccccctgtc ccatgccggc ggcctgccac cgcttcacgt
     5701 tcgacaccga gcgcgaggag tgcgtggagg aggtgctgga ggacggcacg gggtgcgatc
     5761 cgggcaacgc gtgcgtgctg gacgcggtgt gccagcaggg ccgctgcaag gggcgcgagc
     5821 gcgtgtgtga cgacggcaac gcgtgcacca cggacgtgtg cagcccgctg gatgggtgcc
     5881 aggtggtgcc cgcgccgccg tgcccggggg atggggcctg tcaggagggg tggtgcgatc
     5941 cggcgcgcgg ctgccagctg aagcccgcgc gcaacggcac cttctgtggc gaggcccgcg
     6001 ggtgcgatct ggcggacgtg tgcgtggagg ggacgtgcgt gaagagggat cctccggacc
     6061 acttcgtgtg cgcgccggcc tcgccgtgcc agggagaggg ccgctgccgg ggctcggtgt
     6121 gcgagcggcc ggcggcgagg ccgctggtgc cggactggac gtacgacgcg gcggcccagg
     6181 ggcagaagct gcatgatctg ctggtgggcc ccgaggggga cgtgacgctg gcgggcttct
     6241 tcgagaagcc ggtgctggac gcggcgggag acgcgccgat gcaggcgcag gtgacggggc
     6301 ggcggtgcat ggtgtggaac gagcggctgc tgtgcatgga cctgccgcag caggggaagg
     6361 tgtcgctgat ggagcgggcg acggcggcgc cgcggtggag cttcgacctg ggcagggcga
     6421 ggccggacat cgcgcagaag tcctcgacgc tcttcatggc gcggctggcg gtgatggcgc
     6481 cggaccggct ggcggcgctc ttcgaggggt acccggcggg gcaggacgcg aagacgctgt
     6541 gccggctgta ctacctggtg gtgctggacg cggcgggagg gctggtgtcg gcgcagctgc
     6601 tggaggatcc gctgctgtcc gagtgcaacc acccgcaccc gttcgggctg gcgtcggatc
     6661 cagcggggga tctgtacgtg acgttcagcc cgacggtgaa ctcgggggcg ccgttgaggg
     6721 cgggggcgcc gacgctggtg atggcgttct cctcggacgg ggtgccgcgc tggaggagga
     6781 cgctgccctt cccgggaggt gagctggggc tggtgagggg gctgctgatg ccggagggag
     6841 gaacggagcc actgcgcacg tcggatggag agccggtggg gacgctgtcc ctgaagctgg
     6901 ggagggcggt ggcgacgcgc gaggtgctgg tgccgagccc cgcgggagcg acggtgaatc
     6961 cggacgtggc gccggtggcg tctccgcggc tggaggggta cgcggtgccg gggttggagc
     7021 cggcgtggac ataccggctg ccggcggggg cgagcttcgt gtcgaaggag ctgcggctgg
     7081 ggacgtggcc ggagggaggg gtgaagcgga cgatggtgct gggcttcgcg acggagggaa
     7141 gaaggccggt gctggtggga gtgagggcgg gggatgggag cgaggccttc cggtgcgagc
     7201 tgggctactc gccgcggacg attccgcagc tcttcgagct gggacctgga tcgctgacga
     7261 tgatggacgg agcgacgagc tgcggggagt gcgatccacc gttctcggag agccgggcgc
     7321 ggttccagcg cttcacgctg ccggggctgg agccggccga ggcgccctgg ccggggacgt
     7381 tcggcgggcc gggacatgat caccacgagg atccggtgcg cgcggcgccg tgaggcggtc
     7441 cgtgagcatg agccaggcta cctgggctgc tcgaaagcga gcgcgtagct cgtgttcttg
     7501 ctgcccccgg ggttcttcac gaggatgccg cgcgccacga ggtccgtgag ctcgcgctgg
     7561 gcggtatcga cggagcactt gccgagcgcc gcccacttct tggccgtgag cttgccttcg
     7621 aagccatcca acagacggtt catgactgcc ttctgccggg ggctgaaggg ctcacgtgcg
     7681 tagtgctgcc agaagtccgc cttgcgcagg acaccggcgc acgtggcctc ggcggcatcg
     7741 atggcgcgcg cgtagcactc gagaaaccag acgagccaga cggtgacgtc cagtgagccc
     7801 ttctgggtgc gctccaacgt gtcgtagtac gcgctgcgtt cgagccggat ttgactcgag
     7861 acactgtaga agcgctggct ggattgctcg agctgggcca gggccatgtc cgtgatggcg
     7921 cgtgcgatac ggccattgcc atcatcgaac gggtgcacgg tcacgaacca gaggtgcgcg
     7981 agcgccgcgc ggagcaggcc atcgagcagc ggtggggcgt tgaaccagtc caggaaccgt
     8041 tccatctccg cgtcgagccg ctccgccggt ggcgcctcgt agtggatctt cgtccggccc
     8101 acgggcccgg agaccacctg catcggcccc tccgagtcct cacgccatcc accgaccttg
     8161 atgcggtgga agccagagta gcccgtgggg aagagcgcgg cgtgccagcc caccagccgc
     8221 tccttcgtga ggggcgcggc gaagttcccg gtggcgtcca gcatcatcgc cacgacttcc
     8281 tccgtcttgc gatcgggatc ggatccgctc agcgcggcat cgggcacgcc cagccgtctc
     8341 gccaccgagg accggacgct ctcgcgatcc aggagctctc cctcgagctc ggagctcttg
     8401 aggacgtcct cggtgaccgt gtggacctgg gcctcgagcc ggagctcgaa gcccagccgg
     8461 accatgcttc cgagcaagcg gccctgcttg taacgggctt ccgccagggg ccccaccacc
     8521 ccgccatccc cccaggtgaa gcctggccat cgcgcctttt cccagaggga cacggtccat
     8581 tctccgcatg tcttgcggag aatatgacgg cattcgccgc attccgccag acgcactccc
     8641 gccgagggac gcccggagag catccggggg agcacccgtt cctgccccgc gtccgcgccc
     8701 ctagcttgag ggggtatcga cgaaaggcgg tgacaccgtg acgcagcccc cgtttccgag
     8761 gcgcggcctc ctcgctcccc tggcggcggt gctggtgtgg agtctcggcc ctctcgccgg
     8821 ggcccaggtc accgtctccg tccgggagcc cctcctgctc caggtaggcg agcgccgctt
     8881 ccaactccag gtgggctccg agtccatctc cggcggcggg ctcgagctgc gccgcgtcca
     8941 gggaggcctg cgcggcacgc tgaagggcca gcccgtggcg ttgaagtgga acgaggacgg
     9001 tgccatcacc ggccgggcgg ctggtgcgtc cgtgcagctc gacgccatct cccgcgcgcc
     9061 tcagcccggg ctcatcctgc gcggctggtt tggcgcggat ccggccgagc tgacgctgac
     9121 acccacgggc atctccggca gcgtgggcgg gtgtgactac tcgctgccca tggccggcaa
     9181 tcgctacacg ggctggcgca cgtgcgacgc cacccgcggc ccgcccgcgc ccgtgacgct
     9241 gcggattccc gacaacctcg tcccgctcgg cctcaccgag gaaggcgccc tcctggccct
     9301 cctgctctcg gacgaggccc tccctccggc tccctccacg ggggagacac cgggcgtggg
     9361 cggctcgggc accccatctc catgaggaga acccagacac aggaggctcc catggcacgc
     9421 aaggcgttgg catggctcgc cgtgctcggg ctggtggccc cggcgggcgc gcaggaggtg
     9481 ttgggcggag acgaccttcc cgacaacatg gacgagttcc gccggacgcc cctcacggat
     9541 gacgttccca tcaccgacga ggaagcgggc gtgggcggct cggggacggc cggcaccggc
     9601 gacggggccc gtcagggcga gctccatggc gaagtggtca gcgtgcgggg agcgcagctc
     9661 tggctgcggg agggcggggc cgtctttccg atcgagctga cgcaggagac gcgcttcacc
     9721 ccggaccgga gccaggcgct ccagccggga caggaagtgc gggcgcgctt cacgctcgag
     9781 ggggacggtt atgtggtgaa cgccctggag cccaccgggc aggtgccggt ggagaagcag
     9841 cccggggaac ggtgagcgag aagaacggat tgcgtgcacg cggagccggt ctggggtaat
     9901 cccgcgcctc gtgccgagtg ggagagcgat ggaagaccgt ccgtacgtcc tcatgtccag
     9961 ggacgagccg tcacagactc ccgcgtcgac caggataccg atgcagaccg agcccgccgc
    10021 gatcgccttc tgccgggagg tgctgccggc ggtgtcgcgt accttcgcgc tgaacattcc
    10081 cgtgctgccg cgtccgttgg acacggcggt gatggtggcc tacctgctgt gccggatcgc
    10141 cgacacgctg gaggacgagg cccacggccc ggcgagcgag gtgttgctgg cggaactggc
    10201 acggctgagc acgctgccgg cggggtggga ggcggacgcg cggcgcttct cggaggaggg
    10261 ggcgcgggtg ctgcggacgc aggcaccgga ggccgaggtg cggctggtgg cggggacggc
    10321 gcgggtgctg gaggcgttgg cgctgcacgc cgtcccggtg cgcgagcacg tggcgtcctg
    10381 cgtggcgacc atgacgaagg gcatggggaa gatgggggac aagggccgcg cctcgggagg
    10441 aggcctgggg ctggcgagcc tcgaggagac gctggagtac tgctattacg tggcggggac
    10501 ggtgggggag atgctgacgc ggctcttcca gtggtactcg ccggccatcg ccgagcgcgc
    10561 ggcggcactg gagccgaggg cggtggcgtt cggcaacgcg ctgcaactca ccaacatcct
    10621 caaggacgtg cgcgaggacc tggagcgggg cagctgctgg ctgccgaaga cgctgctggc
    10681 cgagcatgga ctgacgcccg aggcgctgct ggagcccggc aaccggggcg aggcgatgaa
    10741 ggcccacggg cagatggtgg cggtggcgca ccgggagctg cgcaaggcct tcgagtatgt
    10801 gatggcattg ccgggccagg agcggggcat ccggctgttc tgcctgtggc cgctgttcct
    10861 cgcggtgatg acgctgcgca agctgtatgg gaatgcggcg gtgctggagc ggcgggccgt
    10921 gaaggtgtcg cggcgcacgg tgaagtgggt ggtggcctcg acgaggctgc tggtgggcca
    10981 ggacgcggcg ttgaagctga tgttctccac gctgacggcc ccgctgcccc ggtagccctc
    11041 tcagttccac ggcagggcgg agcgtttcgc ccagtaggtc tccggtggct cggcgaggcg
    11101 gcgcagtgtc tcccgcgcct cgtccccgag cttcacctcc agcgcgcgca ggttgctctg
    11161 gagctgctcc acggtggtgg ccccactcag caccacggac acccacggct gcgcgagcac
    11221 cgcggcgatg gccaccgcgt ccaccgtggc acccagcgct ccagccacct cgcgcagggg
    11281 acgcagcgct ggatcctcgt tgcgcgccgt gagccgtccg ttggcgacgg cctccttgat
    11341 gatgacgccc cacccggccg catgggcctc ggcgagtacc gggcccgcgg aggactccag
    11401 caggttccac gtggcctgca cgcaggagaa cagcggggag ccgcccacct ggagctccag
    11461 ggcccgccgc agcacctcgg cctgccgggg cccactgagc gtcagcccca cgcgcacccc
    11521 cgagtccctc agccgcccga gctcctcccg gacgcccgtg tcctccagca cgccgctctc
    11581 gaaggtggcc gagtggattt gatacagccg cagccagggc ccgagcagtg tctggctttc
    11641 gccccactgc cggcgcaggg tgggcagcga gtggtccttc acctcgtggc gctcggcgtc
    11701 cacgcgccag gcggcggtat aggtgtagcc ccacttggag ccggccacga cgtcctccgg
    11761 gcgcatgcct cgagccttca accaggaggc gaggaaggcc tcggcccggc cataggagcg
    11821 ggcggcatcg aagtagcgga ggcccgcgag atacgccgca tccagcacct catgggcctg
    11881 gcgctccagg gcctcgacgg agcgatctcc gcggagatcc tccccatggc cgagggtgat
    11941 gtacccgggg cggccgagcg cggcgagtcc gaggcccagg ggagacacgg tgggcccgga
    12001 ggccccgagg gtgcgtggca tggcctcctg cctacctgaa gcgggtggcc ggggggaggc
    12061 tcgtgcggtg gcactgcggg agagtggacg gccggattgt ggagaacttg gggatggagc
    12121 gggcgccttc ctgtaaccga aaggggccga gccacttatc cacaagatat gagccaggag
    12181 agacgaagcc gacgcggggt gctggtgttg ctgccgctgc tgttgctcgg ggggctggcg
    12241 gccggggagc cggagcccgg gcattctcac gaggagggca ccaaggtgta cgccgtccag
    12301 aagaccgatg cggagtggaa acaacagctc acgcccgagc aatacaaggt gttgcgcaag
    12361 cagggcacgg agcgcgcctt cacggggaaa tactgggacc tgaaggccgc gggcacctac
    12421 cactgcgcgg cgtgtggcca gccgctgttc agctcggaga cgaagttcga ctcgggcacg
    12481 ggctggccga gcttctggca acccctgccc ggtgccgtgg acacccacga ggacagcagt
    12541 tggctcatgg tgcgcaccga ggtggtgtgc agccgttgcg gctcgcacct cgggcacgtg
    12601 ttcgacgatg gcccggagcc cacgggcctg cgctactgca tgaactcggt gtcgctcgac
    12661 ttccggccga agtgagcctc acccgccgcg cttgcggaac acgacggtga agttgttgct
    12721 gggcatgtcg atgacccgat cgagctccag cccgtgggcc cgagcctccg cggtgacggc
    12781 gcccagctcg cgcacgcccc aggccgggtt ccgctcgcgc agcgaggcat cgaaggcgag
    12841 attgctcggc gcggtggggc ggccctcgat gaagtacgcc ccgtagagga tgaggggccc
    12901 tccgggtggc agcacccggg cggcacctcg catcaatccc tgacacgact cccacgggga
    12961 gatgtggatc atgttgatgc acacgagggc gtccgcggac tccacgggcc agggggaggc
    13021 acgggcatcc agcgcgagcg gctcgcgcac attgggcaga ccctcttccc ggcgccaggc
    13081 gtcgatgctc gagcgggcga gggcgtcggc gtcggtgggc tgccaggtga gccgcggaaa
    13141 ggcgcgggcg aagaagacgg catgctggcc ggtgccactg gcgagctcga gcacggtgcc
    13201 ctgggagggc agcagctcgc ggaggacggc caggaggggc tcgcggttgc gctcggcgga
    13261 gggggcgtgc tgtttcatgg ctccagggaa tgccggtccc attgctcccc cgccacaaaa
    13321 atccgcccca tttcccctct ccccccggga gagggtcggg gtgagggtat ccgagtccgt
    13381 gttcatccct ggaagcgaga ctccgcgtgc cttgaccccc tccgtgccca gggagaggct
    13441 cacccggtgc tgcccttcct gcagagtcat ctgtcgctga tcgcgggtgt cctcttcaca
    13501 ctgctggtca tcggggtccg ggcggcgagc gcggacgcgc agttccgcaa ggagctcggc
    13561 agggcgctcg gcttcctgat gacgttcctg gtgctgcgcg tggtggaggg gcagttcggt
    13621 gagctgctgc actccagggt cctcccgctg ctgcgcgtgg cgtggatgct cgcgttcgcc
    13681 tttggtggca tccgggcggc gatgtcgctg ggcgtgttga cggtgacgcg cctgggcatc
    13741 cgcaccccgc ctccgaagat cctccgggac gtggtggaga tctccctcta cgtcatcgcc
    13801 gtggtcccca tcctgcgcgc cgagctggcc atcgatctga cgagcctgct ggccacctcc
    13861 gccatcgtct cggtggtgct cggtctcgcg atgcaggaca cgctgggcaa cctcttcgcg
    13921 ggtctgtcct tgcagctcga gcgcccctac gacgtgggcg actgggtcac catcaaggag
    13981 atcaccgggc gggtggtgca ggtggcgtgg cgcgccacga ggctggagac ctcccgcaag
    14041 gagatcatca ccctgcccaa caacatctgc tccaaggagg cggtgaagaa ctactcgcgg
    14101 ggcgggcagc cggtgggggt ggacctgtcc ttccatggcc cgtacgaccg ggcgcccaac
    14161 gaggtgaagg aggcggtgct ggaggtgctg gagcaggtgc cgctggtgct gagcgcgccg
    14221 ccgccgatgt gccgcacggt gggcttcgag gagctcggca tccgctacca ggtgcgctac
    14281 tacgtggagg acttctccaa cgccgacgcg gtgatggccg agttctacac gcgcatctgg
    14341 taccgcttcc ggcgcgaggg catcgaggtt cccgcgcagc gcaagctgaa catgtcgctc
    14401 ggggcgccgg gctccgagtt ctccgaggag ctggtcgctg acatgctgcg gcgggtggac
    14461 ctcttcaagg tgttgcgcga ggaggagcgg gcgaagctgc ggcgggagat ggtgccccgg
    14521 cgcttcgccc ggggcgagca cgtcattgaa caaggcgaga agggcaacac cttctacctg
    14581 gtgggccggg gcgagctgag cgtgcgcacg ggcggggtgg aggtgtcgcg gctgtcgcgg
    14641 ggcaactact tcggggagat gtcgctgctg acgggcgagc cgcgcacggc gacggtggtg
    14701 gcgctcacgg acgtggtgct gctggagctg ggccggccgg tgttcgcgcg cctcttcgag
    14761 gagcacccgg agctggcgcc caagctgtcg gggatgctgt cgcaccggcg catgcagctg
    14821 gaggcggcga tgacggcctc gggcgagacg ctgcccatca ccgaggaggt ggacatcctc
    14881 ggcaggctca agagcatctt ccggctcgac tgagccctgg aaacgagaag ggtggagaca
    14941 tggagccccc cagccccatg tccccacccc ggtacctcgt gtacgcagtc cgtcctactt
    15001 caagagctac tcgtactgca cctgggaacc gcccgagctg ttcacctgta cgctcgcggg
    15061 cttcttcccg gccttcaccg tcgagccacc cgacaggttg ccctggatgc tgcgctcggg
    15121 ggaggcctcg acgcgggtgc cgccgctggc cgtcacctgg agcgactcga gccgcagctt
    15181 gtccgcctcg atgaccgagc caccgctgcc gatgaccgtg agctcccccg tgctgccctc
    15241 gaggcgcagc tccgagccgc cgctggccgc cacctggagg ttcttcgcgt ccaccttgat
    15301 gacgtccacc tcggagccac cgctggcggc cacatcgaag ctgtccacgc gcgtggcctc
    15361 ggcgtccacg tcggcgccgc cgctggccgc cacgctctcc acgcgcgggc tggtgacgta
    15421 caggcgcacg ttcttgaggc ccttgccgaa gtaggacgag cccttctcca cctgcgtcgt
    15481 cagcacgccg tccttcacct cgagcttcac ccgggccacg tcctccttgc tgccctccag
    15541 gcgcaccgac ttgggacccg gcttcacctc ggcgcggatg ccgtagccca cggccacgcc
    15601 acggaaatcg gggacctcga tctgcccggc cttggcggcg tcctgcgcga agacgggcgt
    15661 ggaggccagg agggcaacgg ggaggagcag ggagcgcagc tgcatggtgg acctcgggaa
    15721 gggagaggcg cggagcctcg tgtccttcag ggtacgcacc gccgcgcgag cgattgcaca
    15781 cggcccgccc ggccgctcac tcccggccga gcttctcgag gggcgcgcgg atggaggtga
    15841 cctcgcccgc cttgatttcc acctggagct tcaggggttt gaagcgggga gccaccagcc
    15901 gcagggtgtg cttgcccggc gcgaagggca cccggaagag cggcgtctcg cccagcaccc
    15961 ggttgcccag gtacaccttg gcgtagggct cggtggcgag cgtcaggaag cccttgtccg
    16021 ccgagggctc ggccgcgccc gtgcgctcgc gctccagggc ctgccacgcc cggtccgcct
    16081 cgtccgccgt cgtcacctgc tcgggcgatg tctccacgtt ggacgcggtg cgtggggccg
    16141 tccggcgcga gggcgccacc ttgccgcgct tcgccggctg cgtcgtctcc agggcctcgg
    16201 tgtccggagc ctcggcttcc ggagcctcgg cctctggagc cttggcctgg ggcgaggcct
    16261 ccgccggttc cccggtcgcg ggcagggcct cgttcttcac ctcgggcggg gccggagggg
    16321 tgccggcggc cgcgtccgtg gtgggtgcgg ctgccagggc gtcggtggga ggcgccgcgt
    16381 ccggcggagc gccggcttcc ggtgtggccg cggcgggctc gagggcggcg gcccctggcg
    16441 tctccggcgt ggcgctcgcg gcagcggcct cgggagccgg ggcggagtca cccggggggg
    16501 tgggggcggc ctggaccgcc agcggggcct ccggggcggg gagctcgatg gccgcctcgg
    16561 gtgggggtgg gaagagctgg gaggacacca gtcccccatc cagcctcagc acgacgaggg
    16621 cggcgagtcc tcccacgagg aggagcagca ggagcacggc ccacagcacg ccccggcgcg
    16681 agggcgcctc cgaggccccg ctggagacgg tggcctcctc cgaggcgtct tcctcgcgct
    16741 tcaccggggt gtgccggcgg gagatgggct gggggtgggc gggcgtgagg tcttcctcgt
    16801 ccggctcgtc gctccggggc cccgggaagg agcgggaggc ctcggccggt ggcgacagga
    16861 agggcacggt gcgcagctcc ggctcctcgt cgtcctcggg ctccaccggc cgggaagcgg
    16921 gggacggcgg ccggagaaag ggggcggtga ggagctcggg cccctcgtcg tcctcgggca
    16981 cccccgcggg cggccgggtg ggcgcggccg gtgcctgcag gaggggcatg gtgaggagct
    17041 ccggctcctc gtcctcgggc tccggcgtcc gggccagtgg tgcgcgccgg ccgggcacgg
    17101 tggggctctc ggaggggagc ggcggcgcgg ggggcccggg agggaacgtg ggcgagccgg
    17161 tgggcagggt gacggcgtcc aggtgctcca gcgtggagcg gcgtgccgcg cgggtggagt
    17221 cgtaccgggg ctgggtggcg tccgagtccg aggcggcggg ctgctcgccg gtgggcgtgg
    17281 agcgctgcgg ccggatgacg gccgtcttca gcccgggctc gcgcgtctcc ggaagcgcgg
    17341 gcacggcgtc ggagcggccc aggctgctgc gagggcgcgg ctcggcccgg gtctgctcgg
    17401 gggaggcggc ccggccctgc tccacgggcg tgggggcgcg caccgggcgg ggcggctcgg
    17461 tgagcacggg cagcgagggc agggtggagg gatccacctg cgcgcgggcc ggggtggcga
    17521 gcggggcccg gggcggctcg gtgagcacgg gcagcgaggg cagggtggag ggatccacct
    17581 ggacgcgggg cgggcgggcg cgggaggtgg acggggccgg cggctgcaca cccgtctcct
    17641 cgggaggagg cggcggcgag accgggaact gggaggagga ggcggtgcgc ctgtcacccg
    17701 ggagcgagcc ggggggcttc gcgaccacgg ggtaggggac gagctccgtc tgatccggcc
    17761 gcgcggggcc gggcggcggg agctggggcg cggagatggt ggggaggcgc ggcgcgtggg
    17821 gggtgggggt acgagggccc accggagcgg ccactccggg cgaggacggc gtcgcgggcg
    17881 cggcagtcgg tggggtggac gcctccttgt ccgggaagag ctgggcgagc ttcaccacgc
    17941 cggtgctgtc cacgccggcc cggccgctgg ccagcagctg acgcgtctgc tcgcggcgct
    18001 cggcgaagag ccgccgcagc aattcgctgc tctgctcggg cagccagatg agggggccca
    18061 ccgcgcgctc cagggcgcgg gcgaactcga gcgtggtggc gtaccggtcc gcccgcttgc
    18121 gcgcgagcgc cttgagcacg atggcgtcca gctcgggggg aatggccttg ttggcgcgcg
    18181 agggctcggg gatgggcccc ttgagcaccg cgttgatcac cgccatgggc gccttgcccg
    18241 ggaagagccg catgcccgtg aggcactcgt gcagcaccac gcccaggctg aacaagtcac
    18301 tgcgcgcatc cagcggctcg ccgagaatct gctccggcga catgtagcca ctggtgccct
    18361 tcaccatgcc ggcggcggtg cggctgacgg aggacaggct cttggcgatg ccgaagtcca
    18421 gcagcttggt gacgccctcg tacgtcacca tgatgttctt ctcggccacg tcgcggtgga
    18481 tgacgggcga gggctggccg agcgcatccg tgaaggtgtg cgcgtagtgc agcgccagcg
    18541 cggtgtccct cacggcggcc aggccgagcc ccatgggcat gggctcgttg gcggcgcggc
    18601 aggcgcgggc cacctccagc agcgtggcgc ccgggacgaa ctccatggcg aggaacagct
    18661 cgccgtcgtc cacgtccaag tcgaacacct gggcgatgtg ggggtggttg aaggcggcgg
    18721 tgaccttggc ctcgtccagg aacatctgga cgaactcctc ctggccctgg atgtccggga
    18781 ggatcttctt gagcaccacg ggcttctgga agccggccag gccccgcttg gaggcgagga
    18841 agatctccgc catcccaccg gtgctcaggc ggcagagcac ctcgtagttg cccatctgcc
    18901 ggccgcgcac atcacccggc gcgaaaggga gcttcgaccc agccattcga gaaaaccaag
    18961 cttataggac tcggggcccc aaggtgaaag ccatcaccgt gattttcgcg tgagagcgca
    19021 atggcagcgg attccaccca cacttcccct cccgcggtgg gggggaagcg gacgcgccag
    19081 gcgccggggg agacgcgggg ctcgagcggc ccttcttgag aagcaaaaga aaactccagg
    19141 aggcacggaa cgcccatgcc ctgggtgcgg cgggaggcgg ggacaatccc taccggcggt
    19201 acgagggggc tgttcactgt ccagcgcgtc acggaggcgg ggttgggcag caacgcttcc
    19261 ggagatccga ccccggggtg ccgctgcaag ggcttgggcg tgtgtccaca ttggcggaac
    19321 cgaaattcca tccaggtggc cggtacgacg gtggggcaaa aaactttcag tgttcacgta
    19381 aatcagctct ccacgacaaa cggagttccc atggcgaggg agaaggcgga gcgcgtgcga
    19441 acgcgagaga gcggcctggg ttaccgaatg ggaccggggc tgggggcggt ggcggaggtg
    19501 gaaggggagc tgcactcggc ggggaggttg gtgcagctgt cgccggagca tctgacgttg
    19561 agcctgacga ggcccacggg gctgaggccg ggacagcgga cgaacgtgtt gttgggggtg
    19621 ggaggcgagg cccagatgtt gagggccgag gtgttgaatg tgtacgagcc gggcccggag
    19681 gagcagccgg agctgagcct gcgcttcgtg gcgccgccgc tggaccaggg ccgtcacatc
    19741 gtgacgatgc tggagggctg gagggaccgg ggccagctcg aggcgccgag ctcacacccc
    19801 atctggcggg agcggattac gcgggtggac cggattggcc gcatcttcga ggcgctgacg
    19861 gcgaggcggt gccggggcat ggcgcgctgc gcgggtgggg atgtggagct ggtggcggcg
    19921 ctctacgaca agtacgacgg gcgggtgtcg tgggaggtga ggggctcgtt gccaccggtg
    19981 cccttcacgc tggaggtgtt tggcttcagc tcggtgctgc acttccaggt ggagcaggcg
    20041 gtctacgagg acgggctgtg gggcgtgccg ctgccgcgcg agctggtgcg ctaccggcac
    20101 cgcaagctga ggcgggcgcc cgcgggggag gggtgctcgg cgcgtttcgc gcatccgctg
    20161 tggccgcagg tgaaggtgga gcgggagctg acggatatct cctacgaggg cctgtcgttc
    20221 gcgacgcagc cgggggagga cctgctgtac ccggggctgg tgctgccgga gctggaggtg
    20281 gggctgccgg gaggggagcc ggtgaggatg cgggcggagg tgcgcaacat cacgggcacg
    20341 gcgctgggca gacggtgcgg gatgaaggtg gagccgctgg gggagcggga gctggcgcgc
    20401 tggcgggagc tggtggagga gcagagccac ccgaacacgc gggtgtctgg ggattggaac
    20461 cgggggacgt gggatctgtt cgagcgctcg gggtacttcc ggctgtcggg gaagagcccg
    20521 ggggacttcg agcggatgca ggcggagtac cgggaggcgc acgagaagct ggaggggtac
    20581 cggaggctgg gctaccgggt ggtgaggccg atgccgagcg gggagtcggt ggaggcgagc
    20641 ctgtcgtggc tgaagccgta ctcggggagc tggctggcgc accagttggc gaggcaccag
    20701 ccgcgcaacg agaagctgag gagcacggcg cgcgaggcgc tgcgggacgt gtatttgaga
    20761 ggcttcgagc cggcgcagac ggacccggag gtgaagtggt tcctggcgta ctgcgaggcg
    20821 aacgtgaggt gggtgcgctt cacggcgttc gacttcgcgg agtggtacca gcacacgggg
    20881 caggcgtgca tggtgccgtt ccgcttcatg gaggcggacg cgaggcggga gtgggagatg
    20941 ccggagggct tcagcctggg ggcgccgacg gaggaggaga aggcggcgct gttcgagcgg
    21001 ctgaaggaga cgaggccgga ggcgtaccgg gaggc
//
