LOCUS       NZ_LN831790            24555 bp    DNA     linear   CON 08-APR-2024
DEFINITION  Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 =
            NRRL B-24963) chromosome 1.
ACCESSION   NZ_LN831790
VERSION     NZ_LN831790.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces leeuwenhoekii
  ORGANISM  Streptomyces leeuwenhoekii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Gomez-Escribano,P.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2015) JIC, Department of Molecular Microbiology,
            Norwich Research Park, Norwich, NR4 7UH, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001013905.1-RS_2024_04_08
            Annotation Date                   :: 04/08/2024 03:45:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,096
            CDSs (total)                      :: 7,005
            Genes (coding)                    :: 6,806
            CDSs (with protein)               :: 6,806
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 82 of 199
            Pseudo Genes (incomplete)         :: 160 of 199
            Pseudo Genes (internal stop)      :: 10 of 199
            Pseudo Genes (multiple problems)  :: 49 of 199
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:33:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7744175
            Orig. end                         :: 7768730
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LN831790.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24555
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="33"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24555
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24555
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14555]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14555
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(48..58)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     misc_feature    1203..1217
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    complement(1609..1625)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 14.6"
                     /tool="antismash"
     gene            2231..2485
                     /locus_tag="BN2145_RS34675"
                     /old_locus_tag="ABM27_RS34025"
     CDS             2231..2485
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975335.1"
                     /locus_tag="BN2145_RS34675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34025"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_029386153.1"
                     /transl_table=11
                     /translation="MRPYDDERLLALAAQLERDDPRFARQFRRGRPTRPREYRRTGAWW
                     ALAAALASVAAGVALPHGLLLAAGLVLAGIGLERFDPYR"
     misc_feature    2247..2262
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.29"
                     /tool="antismash"
     gene            2643..3074
                     /locus_tag="BN2145_RS34680"
                     /old_locus_tag="ABM27_RS34030"
     CDS             2643..3074
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031627.1"
                     /locus_tag="BN2145_RS34680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34030"
                     /product="hypothetical protein"
                     /protein_id="WP_029386152.1"
                     /transl_table=11
                     /translation="MIEWAPLGSGARPVPEPAAAPLVWAVAFGGALALVAVVNSVAGPG
                     RTVLALTALSLLAAGLGLCARFTAAPGTALLCWLSLNGFAIPPAGTLTWAGRRDMFWLG
                     CLLAAALAGTALARVVHARAAYRRLTAAPGHEAPEAGGC"
     gene            complement(3256..4173)
                     /locus_tag="BN2145_RS34685"
                     /old_locus_tag="ABM27_RS34035"
     CDS             complement(3256..4173)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN2145_RS34685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ABM27_RS34035"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_049976864.1"
                     /transl_table=11
                     /translation="MPVEQDRGLERAVTAIASLSPEWNAASEHAASGLWRLPRAAEAVE
                     HVLRGDGAALRDRGWMMVRARVAEEISSGRDWTREVAVWLARGEADWAESAQVTGDLAW
                     RARTAGRSALIFLTDAHVAGVDPGTPFGRGLWHSFLTTLRYDFRCGAIEEFFSRGSADR
                     PDLDPYSVALRAFALLGRSRPRGLDLLESVMARAGGNAKAVHALLHGLWLGEHLPDQPQ
                     RMLELLRAPAFAQGLGAEALFRKAAALRRLKRFDEALAALQGAIDCLDPCEVVVHADCV
                     RERSLILAERDVYRRGPGSGGLPA"
     gene            4450..4956
                     /locus_tag="BN2145_RS34690"
                     /old_locus_tag="ABM27_RS34040"
     CDS             4450..4956
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-141). E-value:
                     6.2e-11. Score: 34.8. Matches aSDomain:
                     nrpspksdomains_BN2145_RS34690_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569919.1"
                     /locus_tag="BN2145_RS34690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34040"
                     /product="SRPBCC family protein"
                     /protein_id="WP_029386150.1"
                     /transl_table=11
                     /translation="MAVRHHLIKASPEAVWSVIADGSRYAQWVVGTSESRPKRGHWPDL
                     GAAIEYEVRLGPVRMTNETVVRRCVEGAVLELEAHAGLLGTARIAIELRSWGEQCLVIV
                     DEHPLRGAGGALHNAGLEALIQLRHRAMLARLARLCEARAAGDTRPGTATGEGAVAAGP
                     EAGHA"
     aSDomain        4462..4872
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN2145_RS34690_Polyketide_cyc2.1
                     "
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="6.20E-11"
                     /label="BN2145_RS34690_Polyketide_cyc2.1"
                     /locus_tag="BN2145_RS34690"
                     /protein_end="141"
                     /protein_start="4"
                     /score="34.8"
                     /tool="antismash"
                     /translation="HHLIKASPEAVWSVIADGSRYAQWVVGTSESRPKRGHWPDLGAAI
                     EYEVRLGPVRMTNETVVRRCVEGAVLELEAHAGLLGTARIAIELRSWGEQCLVIVDEHP
                     LRGAGGALHNAGLEALIQLRHRAMLARLARLCE"
     gene            4949..6568
                     /locus_tag="BN2145_RS34695"
                     /old_locus_tag="ABM27_RS34045"
     CDS             4949..6568
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324134.1"
                     /locus_tag="BN2145_RS34695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34045"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_029386149.1"
                     /transl_table=11
                     /translation="MPDAVVIGAGPNGLVAANLLADAGWSVEVLEEQPEPGGAVRHDSG
                     VDADFVSDVFSSFYPLAAASPVLAGLGLTEHGLRWSHAPHVLAHPLSDGTCAVLDRRVD
                     TTAASLEVFAPGDGAAWRRLYEVWESLRPDILDALFTPFPPIRATARLAARLRSAGGLR
                     LARSLVLPVRRLGEEEFRGAGGRLLLAGNALHADLAPEAAGSGGFGWLMSMLGQTYGFP
                     VPVGGSGALTDALVRRLRARGGTLRCGRRVSRVVVRDRRAVAVRTADGETVPARHAVLA
                     DVSVPDLYGGLVEPEHLPAQVLDDVERFQWDFATFKVDWALDGPVPWKSEEAARAGTVH
                     LADGVDELTRFAAQIAMRQVPDRPFTLFGQMTTADPCRSPQGTESAWAYTHVPHDIRAD
                     AGEEGITGSWDAGEQELMADRVERQVERFAPGFRQLVRARRILAPPTLQSLDANLRGGA
                     INGGTTALHQQLFFRPVPGAGRPETAVAGLFLASAGAHPGGGVHGAPGANAARAALRRH
                     FPPGRTRLQRMLAGRDRTGTKR"
     gene            6565..7557
                     /locus_tag="BN2145_RS34700"
                     /old_locus_tag="ABM27_RS34050"
     CDS             6565..7557
                     /NRPS_PKS="Domain: PKS_KR (14-178). E-value: 1.2e-14.
                     Score: 46.6. Matches aSDomain:
                     nrpspksdomains_BN2145_RS34700_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992094.1"
                     /locus_tag="BN2145_RS34700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34050"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_242514047.1"
                     /sec_met_domain="adh_short (E-value: 3.1e-31, bitscore:
                     107.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGRPAVDSPLRNRTVVVTGAARGIGAALALELARRGARLALLGH
                     EKPLLDAVAATVPSAALTWEVDVTDAEALAGAADEVRRRLGPPSAVVANAGIATGGPFA
                     TSDPALWRRVIDVNLTGSAQTARAFLPDLTDTAGYYLQVASSASLGAAPLMSAYCAAKA
                     GAEAFAQALRAEVAHLGIGVGIAYVHWTDTEMIRDADRYTALRTLRVRMPPPASRVSPV
                     DAVAARLAHAVERRRTTVYVPAWLRMAQVVRTAMPPVVLRRTRRELPRLEDARELTATG
                     PLGAGGRADRAAAEETAGRQTGETADPKTETTPDTGERAAKETDGETDE"
     CDS_motif       6607..6696
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN2145_RS34700_0001"
                     /evalue="3.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="BN2145_RS34700"
                     /protein_end="44"
                     /protein_start="14"
                     /score="22.8"
                     /tool="antismash"
                     /translation="TVVVTGAARGIGAALALELARRGARLALLG"
     aSDomain        6607..7098
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN2145_RS34700_PKS_KR.1"
                     /evalue="1.20E-14"
                     /label="BN2145_RS34700_PKS_KR.1"
                     /locus_tag="BN2145_RS34700"
                     /protein_end="178"
                     /protein_start="14"
                     /score="46.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVVVTGAARGIGAALALELARRGARLALLGHEKPLLDAVAATVPS
                     AALTWEVDVTDAEALAGAADEVRRRLGPPSAVVANAGIATGGPFATSDPALWRRVIDVN
                     LTGSAQTARAFLPDLTDTAGYYLQVASSASLGAAPLMSAYCAAKAGAEAFAQALRAEVA
                     H"
     gene            complement(7615..9213)
                     /locus_tag="BN2145_RS34705"
                     /old_locus_tag="ABM27_RS34055"
     CDS             complement(7615..9213)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512786.1"
                     /locus_tag="BN2145_RS34705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34055"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_047122244.1"
                     /sec_met_domain="DAO (E-value: 4.4e-11, bitscore: 41.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSARGGARPPGRDRRARLLPPRPGRERIAGGPPSAAVVGGGIAGL
                     AAATVLAERGVRVVLHEREPQLGGRVSGRPVTLADGTRATMSRGFHAFFRQYYNLRSLL
                     RRADPALEMLAGLPDYPLRHSSGLCDGFRRVPRTPPWNALGFVALSPAFGPRDLLSLRP
                     SAALPLLDVRTRRVHDRLDHVSAHDFLDSLRFPAAARHLAFEVFSRSFFADPRELSAAE
                     MALMFHIYFLGSSEGLLFDVPREPYPQALWDPLARHLAGHGVTVRTAAPVEAVRPRSDG
                     GHDVVDASGARRYDAVVLALDVDGLRALVDRSPGLGDAEWRARVARLRTAPPFLVSRLW
                     LDRPVAPGRPGFLGTSGYGPLDNVSVVSHWEGEAARWAARSGGSVVELHGYALSPATAP
                     DTAAGELTEQLHRVYPETRDARVLDVRHEYRADCPLFPVGGYRDRPTVRTPDPAVVVAG
                     DLVRTDLPVALMERAATSGFLAANALLERWGVRGEGLWTVPDRGRSALLRALARRGATV
                     TGSTTAGREKRRSRA"
     gene            complement(9210..9941)
                     /locus_tag="BN2145_RS34710"
                     /old_locus_tag="ABM27_RS34060"
     CDS             complement(9210..9941)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007379577.1"
                     /locus_tag="BN2145_RS34710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34060"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_047122245.1"
                     /transl_table=11
                     /translation="MTLLRDAALADAFDHGAGAYDRLVALNPGYHGQLRRSARRLGLPD
                     GGSGCRVLDLGCGTGASTAALAATLPGADIVGVDASAGMLRRARAKPWPDRVRFVHAPA
                     EELSRAGVSGPFDAVFAAYLFRNLADPDAVLRTVRGLLAPGGRLAVHEYALSGRRADRL
                     VWSAVCRGVIRPLGTATGDRALYRHLGRSVATFDTAPAFAARLGRAGFDRVRVLPLPGW
                     QTGITHTFLARRPPQRPGGAR"
     gene            complement(10001..11239)
                     /locus_tag="BN2145_RS34715"
                     /old_locus_tag="ABM27_RS34065"
     CDS             complement(10001..11239)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324138.1"
                     /locus_tag="BN2145_RS34715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34065"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_242514048.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 1.3e-97, bitscore:
                     325.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLETGAGRRADAVLQADIVIVGAGAAGLSLAHRLPTAAPGHRAAP
                     SVVLVEPPAGPLRAPRRTWCFWETGAGRFDPAVTASWEWLRVRDRHGAAVRRHIAPVRY
                     KMIRSDDFEALVTGDLGKAPGVRRVEAAVDTVAVLPDGTAEVRGTDAAGVPVRLRGRWV
                     FDSRPPPRPPAARTRLLQHFRGWFVRTSRPAFDPEVVDLMDFRTPQPARGLSFGYVLPT
                     GRRTALVEYTEFGPAPLTADAYDAALEHYTRRVLGIGDARVLSTEQGVIPMTDAVFPRR
                     IARSVFPIGAAGGATRAATGYTFSAVQRQSDAVARAVRAGRAPVPPPPHPARARMMDAV
                     LLRALDTGRIDGPDFFFRLFARVPVRLLLRFLDGETRLYEDLSVGVRTPVLPMLRTAAE
                     VPWLPRRVRPPAP"
     gene            11977..13497
                     /gene="crtI"
                     /locus_tag="BN2145_RS34720"
                     /old_locus_tag="ABM27_RS34070"
     CDS             11977..13497
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670293.1"
                     /locus_tag="BN2145_RS34720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34070"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_047122246.1"
                     /sec_met_domain="DAO (E-value: 1.2e-17, bitscore: 63.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTMPGRTDHVVIVGAGLAGLSAALHLLGAGRRVTVVERDRLPG
                     GRAGRRELGGYLLDTGPTVLTMPQVADEAFAAVGERLRDRVELLPLHPAYRACFADGST
                     LDVHTDATAMEAEVERFAGPREAAGYRRLRTWLTRLYTVQMRRFIDADFDSPLDLLTPD
                     LARLAALGGFGRLDARIGRFLTDERLKRVFSFQALYAGVAPARALAAYAVIAYMDTVAG
                     VYFPRGGMHALPRAMAAAAADAGGDLRFGEEVTHLERSGDRITAVVTAHDRIPCDAVVL
                     TPDLPLAHRLLGRRPRRPLPLRHAPSAVVLHAGTTRTWPHLAHHTLSFGAAWQRTFDEL
                     TRSGTLMTDPSLLITRPTAADPGLAPEGRHLHYVLAPCPNTDIGPGPEAWHALAPRYRD
                     RLLATLDRRGLSGIAAAIEEECLVTPADWTAHGHAAGTPFSVAHTFTQTGPFRPRNLVR
                     GLRNAVLAGCGTTPGVGIPTVLISGKLAAARVTGPPARPRRPVEAARR"
     gene            13494..14555
                     /locus_tag="BN2145_RS34725"
                     /old_locus_tag="ABM27_RS34075"
     CDS             13494..14555
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134618.1"
                     /locus_tag="BN2145_RS34725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34075"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_079164110.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.2e-118,
                     bitscore: 393.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.8e-65,
                     bitscore: 219.8, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="T1TS (E-value: 0.002, bitscore: 16.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQRELDAAGITDPVLRAAYARCRRLNARHGRTYFLATRLLPAAR
                     RPAVHALYGFARFADDIVDDLGTTVGRAERAAALARLEERLRQALTGAAPATEPVVRAV
                     ADTAARYAIDPAHFTDFMASMRSDLTVTSYATYDDLRAYMHGSAAVIGLQMLPVLGTVT
                     PRAEAAPHAAALGVAFQLTNFLRDVGEDLDRGRVYLPADLLAAHGVDRDLLRWSRRTGA
                     HDPRITAALKAAENLTREVYREAAPGLAMLDPVARPCIRAAYVLYRDILDAIAEGGYAV
                     LHRRAVVPARRRAAVAAGGLARVLAARLRAGYPPVPATAPAPAAGTAPAPAAGTAPADG
                     PVPRPEGTREAAG"
     gene            14552..15589
                     /locus_tag="BN2145_RS34730"
                     /old_locus_tag="ABM27_RS34080"
     CDS             14552..15589
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888660.1"
                     /locus_tag="BN2145_RS34730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34080"
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_047122247.1"
                     /transl_table=11
                     /translation="MTAGNNARPGPRAGLSPLRLRRRPVPWERQDPTWRQARPAAITGA
                     LKRALARPSGNWYVVGAAAGVRPDRPLGRTVAGVEVVVWRDARGRLVGGPGACPHLGAP
                     LAASPVRCGTLVCHWHGLALDGTAFAGWEPLPVHDDGVLVWVRLDAVGRERPTPAPVLS
                     PRPPLPAALVSVWEGVGRCAPEDVVANRLDPWHGAWFHPHSFADLTVVREPGAGEPGAG
                     DADDRFVVDVSFRLTRRLVVPVRAEFTAPEPRTVVMRITDGEGTGSVVETHATPLAPDG
                     RGTPRTAVVEAVLATSARPGFALARRLAPALRPLMRTAAARLWRDDLAYAERRRHLRDL
                     GRHPG"
     gene            15846..16037
                     /locus_tag="BN2145_RS38170"
     CDS             15846..16037
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544588.1"
                     /locus_tag="BN2145_RS38170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2945 domain-containing protein"
                     /protein_id="WP_047122762.1"
                     /transl_table=11
                     /translation="MAWNSHGGSTEGMVEREITRRTEAAGRTVDAAPDAPQYEVRSDKF
                     GKRAVHKPSALRKKDPGA"
     gene            16049..16537
                     /locus_tag="BN2145_RS34740"
                     /old_locus_tag="ABM27_RS34090"
     CDS             16049..16537
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324142.1"
                     /locus_tag="BN2145_RS34740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34090"
                     /product="MSMEG_6728 family protein"
                     /protein_id="WP_029386564.1"
                     /transl_table=11
                     /translation="MQTFLPHPGFRDSALVLDRRRLGKQRVEALQVLRGLTVPGYGWRR
                     HPAVRMWTGYEEALVRYGLEVCRVWRERGHQDSCAASLVAGLETWCPGTPVRDQSALAE
                     AGELPPWLGDDAFHRSHRSALVRKDPAAYAELFPGVPDDLPYVWPSSDRERGETPADR"
     gene            16635..17510
                     /locus_tag="BN2145_RS34745"
                     /old_locus_tag="ABM27_RS34095"
     CDS             16635..17510
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072654.1"
                     /locus_tag="BN2145_RS34745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34095"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_029386565.1"
                     /transl_table=11
                     /translation="MDGEPAAVAAARERLGSALFRRVAGPEGPANRARIHGTPGPRWFG
                     PDRPVRVVHGDASMFVGGIRALLLQSLHPLAMAAVAAHSGYRGDPWGRLQRTSTFLAVT
                     TYGTADDAQRAVDHVRAVHEGIRGTTAEGLPYHAADPHLLKWVHLAETDSFLCAHERYG
                     AHPLDAAGYDAYVADTARVATALGVLDPPRTRRELAGQLAAYRPELRATPQARAAARFI
                     LFQPPLPLPARPFYTVLAATAVATLPPWARAPLRLPRLPVAEDLAVRPAGQALVRAVRW
                     AMTPPPDLPG"
     gene            complement(17556..19064)
                     /locus_tag="BN2145_RS34750"
                     /old_locus_tag="ABM27_RS34100"
     CDS             complement(17556..19064)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389312.1"
                     /locus_tag="BN2145_RS34750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34100"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_029386566.1"
                     /transl_table=11
                     /translation="MSDDTAAGLHCLVTGATGYIGGRLVPELLAEGHRVRCLARSPGRL
                     RDQSWAGEVETVRGDVTDSASLAAALRGVDVAYYLVHALGTGRGFEETDRRAARIFGER
                     AREAGVRRVVYLGGLTPAGVPEAALSPHLRSRAEVGRILLDCGVPATVLRAAVVIGSGS
                     ASFEMLRYLTERLPVMVTPSWVRTRIQPVAVRDVLRALVGSARMPDDVSRAFDIGGPDI
                     LTYRDMMARYAAVAGLPRRLIVPVPVLTPGLSSHWVGLVTPVPAAIARPLTESLRHEVV
                     CREHDIARYVPDPPGHPIGFDEAVRLALQRVREARVTTRWSSASVPGAPSDPLPTDPDW
                     AGGSLYTDHRSRTVHASPGTLWRVIEGIGGERGWYSFPSAWAVRGLLDRLVGGVGLRRG
                     RRDPARLRVGDSLDFWRVEEIEPGRLLRLRAEMRLPGLAWLEMYVETDGEGRTRYRQRA
                     LFHPHGLLGHVYWWGVSPFHAVVFGGMARNIARAAAAGRDAGPG"
     gene            19228..19764
                     /locus_tag="BN2145_RS34755"
                     /old_locus_tag="ABM27_RS34105"
     CDS             19228..19764
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978019.1"
                     /locus_tag="BN2145_RS34755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34105"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_029386567.1"
                     /transl_table=11
                     /translation="MISADGRDGREQERSAQGRGARDGEAGERPAATALASFAVQLRRM
                     NGEINRLAHGFAGEHGLHATDVQALAAILDAEEPMTPGRLREYLGLSSGAVTACVDRLE
                     RAGHIRRVRESADRRVVHLRYAPDARQTARAYFRPLAEATASARSRFSEEELSVVVRFL
                     DSLNEELALLRSPRG"
     gene            19941..22019
                     /locus_tag="BN2145_RS34760"
                     /old_locus_tag="ABM27_RS34110"
     CDS             19941..22019
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126160.1"
                     /locus_tag="BN2145_RS34760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34110"
                     /product="MMPL family transporter"
                     /protein_id="WP_029386568.1"
                     /transl_table=11
                     /translation="MSAPPSHTRRTRLLVPLLLLLTWLVVGGTLGPFAGRLGEVATNDQ
                     AAFLPRSAESTEVIAAQRAFRQDESLPAVVVWTFDAAARDGQGAATRALASLTGTPGVA
                     GRPSPALVSRDGTALQGVVPLRTDLGDRLPDVLDRVRDAAERVPGATVHLAGPAASQAD
                     LSDAFAGIDGLLLAVALVTVLVILLLVYRSVLLPFVVILGAVFALGLACAIVYALADHG
                     AVRVDGQVQGILSILVIGAATDYALLLTARYREELGVRGDRFAAVRAALRESWGAIVAS
                     AATVALGLLALLLSDLTNNRALGPVGAIGIVCAVLSALTFLPAVLVLLGRAAYWPAGAR
                     AAGERPGVWHRVAHLVDRAPRRVWAVALACLLAGAAFAPSLTSKGVPLDETFVGDAPSV
                     AAQRVLGEHFPGGAGNPAVVIANADRAEQVVAAARDTRGVAGAVPVTASGGPGEGEPLT
                     VGGRVRIDVTLRAAADSDEARETVARLRGALHAVPGADALVGGYTAQRHDTLETAERDR
                     TLIVPVVLGIIFVILVGLLRSLLLPALLVVTVALNFLATLGVSALVFRHVFGFTGTDPS
                     VPLYGFVFLVALGVDYNIFLMSRVREEALAHGVRRGILRGLVSTGGVITSAGVVLAATF
                     AALGVIPLAFLVQIAFIVAFGVLLDTLVVRSLLVPALSRDIGAAAWWPGRLSRAPGR"
     gene            complement(22094..23632)
                     /locus_tag="BN2145_RS34765"
                     /old_locus_tag="ABM27_RS34115"
     CDS             complement(22094..23632)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446557.1"
                     /locus_tag="BN2145_RS34765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS34115"
                     /product="MFS transporter"
                     /protein_id="WP_242514049.1"
                     /transl_table=11
                     /translation="MSDAMPDGRPGPRGRATVPKTVADMPRQVREELSRRLHRKKGAFR
                     EEDVQVVERPLLKRAVGASALGNCMEWFDFGVYSYLAATIGKVFFPGASPGAQLISSFA
                     TFAAAFVVRPLGGLVFGPLGDRIGRQKVLATTMIMMAIGTFSIGLIPGYASIGIAAPAL
                     LLLARMVQGFSTGGEYGGATTFVAEYSPDRRRGFLSSWLDFGTFVGYALGSALVTVLNL
                     ALTDAEMLSWGWRIPFLIAGPLGLIGLYMRLKLEESPAFQKQLDEHEKSLAQASAGSEF
                     KTIIRRHWRPLLVCMGLVLLYNVTNYMVTGFLPTYQTENVGRSTSFADLLVLIGMVWIV
                     LLITFLGRLSDRVGRRPLYAVGAAAMIVLAVPAFLLLKADGTWQPVVGVLVLSTLLACF
                     AAPSAATLPALFPTAVRYAAMGIGFNFAVAAFGGTTPLVTEALVNATGNDLVPAFYLMA
                     AGLIGLVTVRFLPESAQVPLNGSQPMVGSRQELRDLIRTSRELYHFDEDRSAAR"
     misc_feature    complement(23658..23678)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 18.84"
                     /tool="antismash"
ORIGIN
        1 tgccgaagag cacgtagtgg aagtgggcga tcacgaagta gctgtcggtg acatggaagt
       61 ccagcggcgg agaggcgagg aggacgccgg tcagcccgcc gaagaggaag gtgacgagga
      121 agccggccgc ccacagcatg ggcggctcga acgacagcga gcccttccac atggtgccga
      181 tccagttgaa gaacttcacg cccgtcggca cggcgatcag gaagctcatg aaggagaaga
      241 acggcagcaa cacggcctgg gtggcgaaca tgtggtgggc ccagacggtc acggacaggc
      301 cggtgatggc gatggtggcg ccgaccaggc ccatgtaacc gaagatcggc ttgcgggaga
      361 agaccgggat gatctcggtg atcacgccga agaacggcag ggccaggatg tagacctcgg
      421 ggtggccgaa gaaccagaac aggtgctgcc acaggagcga cccgccgttc tcggggtcga
      481 agacgtgggc gccgaactgg cggtccgcct gcagcgcgaa cagcgcggcg gccaggacgg
      541 ggaaggccag caggaccagc accgaggtga gcagcacgtt ccaggtgaac agcggcatgc
      601 ggaacatggt catgccgggg gcccgcatgc agatgatggt ggtcacgaag ttgaccgcgc
      661 ccaggatggt gccgaacccg gacagcgcca ggcccatgac ccacaggtcg ccgccgacgt
      721 agggggtgcg ctccccgccg ctgagcgggg tgtaggcggt ccagccgaag tccgcggcgc
      781 cctgcggggt gaggaagctg ctcaggacga tcaggccgcc gaagaggaac agccagtacg
      841 agagcatgtt cagccgtggg aaggcgacat cgggcgagcc gatctgcaac ggcatgatcg
      901 cgttggcgaa cccggcgaac gtgggggtgg cgaagagcag cagcatgatc gtgccgtgca
      961 tggtgaacgc ctggttgtac tgctcggcgg atacgagctg caggcccggc cgggccagct
     1021 ccgcccggat caccatcgcc agcaggccac cgatcaggaa gaacccgaac gacgtgatca
     1081 ggtacagatg cccgatcttc ttgtgatcgg tcgtggtcag ccaggagacg accacgcggc
     1141 ccctgccgcg gcgtcccttc gccgccggga cgggagcgat cggttcagtc gtatgtgtcg
     1201 ccatcagttt cctcggtcga tgcccgtcgg cgcgcatgcg gatgcggtgg ccgaacggga
     1261 cacggggggc gcgtccggct ccggctgcgt gtgtcgcgca gcgcgtgccc ggagtaaccg
     1321 aagttagtcc ccctttcccg acacaacgtc accaatggcc tcgtttgggc cgaatggctg
     1381 aggaatttcg atccgtccgg gtgtctccgg gcgcggccgg ggtgacgtcc ccgacgacgc
     1441 cgcacgccgc cgccctcgct gccccgtcac ccgaatggcc cctgcacgtt tctgatcccg
     1501 gtgaatgtgg ggtctcctgg acagggacgg cggcgtccac cttgggaggc cggaacatgt
     1561 acgagatgtg cgtgggcccg gaaaagccgg gcggagcatt ggtgtggcac gtgatggcca
     1621 aacaagccgc ggccaccttg tgcgggcagc gactcgccgc tcgcatcgag gcgtccagag
     1681 ccgaacgggc acgccactgc ccggactgca tggcctcgtt cgcggagttg atgaccagca
     1741 cgccgcactg acgcctgccc gcgacggcgg ccggacaccc gttccctcga gcggggtccg
     1801 gcctccgtcg tgcccgcctg ccaccgcgta cgggaaagcc gggacggcca cccttccgtg
     1861 ccgcgggtgg cgctcgacgg gtgcgtgcgg acattcgccc gcgaccgtgc ggggcacgca
     1921 ccgctcccgt ggcggtcccg ccccgcgggc cgacctcccc cgccccgcgt cgagcgcccc
     1981 ggcgaggcgg cccgcggacg agtcgccggt aagggcgagg gcgcagaccg atggcgtggg
     2041 ggccgagggg agcggccgtg cgccccggtc gggcgggccg gggggctcga cgggagccgc
     2101 cgggccgcgc cgtcatccgg ccgtacctcc gcgcggtcgg gaactcggag acgtggcaag
     2161 ggcgttgact tctcacccgt ccggccttcc gcgcgctttc ccccagtggc ggacatggga
     2221 agagggagcc atgcgcccgt acgacgacga acggctgctc gctctggccg cgcagctcga
     2281 gcgtgacgat ccccggttcg cccgccagtt ccggcgtggc cgccccaccc ggccccgcga
     2341 gtaccggcgc accggcgcct ggtgggcact ggcggccgcc ctcgcctcgg tcgccgcggg
     2401 agtggccctg ccccacgggc tgctgctcgc cgccggtctg gtcctggccg gtatcggcct
     2461 ggagcggttc gacccgtacc gctgacgggg tccgccgcac ggcccggcgg cggcccccgg
     2521 tacgccaccg gtgtccgacc ccgacctcac cgcgggtggc gccgcggtgg gagaatcagc
     2581 ccgcaggatc ggggagcgat gccgtggtgg gggccgcccc gggagcggaa ggagccgtca
     2641 acgtgatcga gtgggcaccc ctgggcagcg gtgcgcggcc cgttcccgaa ccggccgcgg
     2701 ctcccctggt gtgggcggtc gccttcggcg gcgcgctggc cctggtggcc gtcgtcaaca
     2761 gcgtcgccgg tcccggccgt accgtcctcg ccctgaccgc gctgtccctg ctggccgccg
     2821 ggctcggact gtgcgcccgg ttcacggccg ctcccggtac ggcgctgctg tgctggctct
     2881 cgctcaacgg cttcgccatc ccgcccgccg ggacgctcac atgggccggg cggcgggaca
     2941 tgttctggct cggctgcctg ctcgccgccg ccctcgccgg caccgccctg gcccgtgtgg
     3001 tccacgcccg tgccgcctac cgccgcctga cggcggcacc cggccacgag gccccggagg
     3061 cgggcggctg ctgacggcag gtccggtccg tgtccggacc ggagccgagg tgccctgtcc
     3121 ggacgacgcc gccgtgccgc cggcaccgga ggcgaaccgc ggcgtcaaga gcgcgactgc
     3181 cgccccgctc gccgtacgac gggcgcgggc ggcacggagc gggtgtcatg gcgccgtcgc
     3241 tacaccgccg ccccgtcagg ccgggagacc gcccgacccg gggccgcgcc ggtacacgtc
     3301 ccgttccgcg aggatcagcg accgttcccg tacgcagtcg gcgtggacca ccacctcaca
     3361 gggatcgagg cagtcgatgg cgccctgcag ggcggccagc gcctcgtcga accgcttcag
     3421 ccgccgcagc gcggccgcct tccggaacag cgcctcggca cccagcccct gggcgaacgc
     3481 cggggcgcgc agcagctcca gcatccgctg cggctggtcg ggcaggtgct ctcccagcca
     3541 caggccgtgc aggagggcgt ggacggcctt ggcgttaccg ccggcgcgcg ccatgaccga
     3601 ctccagcagg tccagcccac ggggccggga ccggcccagc agggcgaagg cgcgcagggc
     3661 gacgctgtag gggtccaggt ccgggcggtc ggcggagccc cgggagaaga actcctcgat
     3721 ggcaccgcac cggaagtcgt accgcagggt ggtcagaaag ctgtgccaca ggccgcgccc
     3781 gaacggcgtg cccggatcca cccccgccac gtgggcgtcg gtaaggaaga tgagtgcgct
     3841 gcggcccgcg gtccgcgccc gccacgccag gtcgccggtc acctgggccg actcggccca
     3901 gtccgcctcg ccgcgggcca gccagacggc cacctcacgg gtccagtccc gccccgagga
     3961 gatctcctcg gccacccggg cccgcaccat catccacccc cggtcccgca aggccgcgcc
     4021 gtcccctcgc aggacgtgct ccacggcctc ggcggcccgg ggcagtcgcc acaggccgga
     4081 cgcggcgtgc tcggaggcgg cgttccactc gggggacagg gaagcgatcg cggtcaccgc
     4141 ccgctccagg cctcggtcct gctccacggg catcgggcca cctcctccac gtcccggccg
     4201 ccgttcgccc gggcgttccc ggcacggctc cgggccggtc atgtcatgtc tgccgcgcgc
     4261 gggcggttcg gtaaccgcgc cgggcccggt gcccccgccg cccacggccg cgagggacgg
     4321 cgcccgcgcc cctgctccct gggaatacgc cgtaccgggc cgttctcaga ggggaccggt
     4381 tgggcccgcc cggaaggggc actcactgcg ggtgtcgcag tggcaccttc gagagcccgg
     4441 gaggcgtgcg tggcagtccg tcaccatctg atcaaggcga gtccggaggc ggtctggtcc
     4501 gtcatcgcgg acggcagccg atacgcgcaa tgggtggtgg gaacgtcgga gtcccgcccg
     4561 aagcgggggc actggcccga cctcggcgcc gcgatcgagt acgaggtgcg cctcggcccc
     4621 gtgcggatga ccaacgagac ggtcgtcagg cggtgcgtgg agggcgccgt cctggagctg
     4681 gaggcgcacg ccgggctgct cggcaccgcc cggatcgcca tcgagctgcg gtcctggggc
     4741 gagcagtgcc tggtgatcgt cgacgagcat ccgctgcgcg gcgcgggcgg ggcgctccac
     4801 aacgcgggcc tggaggcgct gatccagcta cggcaccgcg ccatgctggc ccggctggcc
     4861 cggctctgcg aggcccgggc cgccggcgac acgcgtccgg ggaccgcgac gggcgagggg
     4921 gcggtggcgg cgggcccgga ggccggccat gcctgacgcc gtcgtgatcg gcgccgggcc
     4981 caacgggctg gtggccgcga acctgctggc ggacgccggg tggagcgtcg aagtcctgga
     5041 ggaacagccc gagcccggcg gagccgtgcg gcacgacagc ggcgtcgacg cggacttcgt
     5101 cagcgacgtg ttcagctcct tctacccgct ggccgccgcc tccccggtac tggccggcct
     5161 cggcctgacg gaacacggcc tgcggtggag ccacgccccc cacgtcctcg cccaccccct
     5221 gagcgacggc acgtgcgcgg tcctcgaccg ccgcgtcgac accaccgccg cctccctgga
     5281 ggtcttcgcc cccggagacg gagcggcctg gcggcgcctg tacgaggtgt gggaaagcct
     5341 ccgccccgac atcctcgacg cgttgttcac gcccttcccg ccgatccggg ccaccgcccg
     5401 gctcgccgcc cggctgcgca gcgcgggcgg gctgcggctg gcgcgctccc tggtgctgcc
     5461 cgtgcggcgc ctgggcgagg aggagttccg gggtgcgggc ggcaggctgc tcctggccgg
     5521 caacgccctc cacgccgacc tggccccgga ggccgcgggc agcggcggct tcggctggct
     5581 gatgtccatg ctcggacaga cgtacggctt ccccgtaccg gtcggcggct ccggcgccct
     5641 caccgacgcc ctggtgcgcc gcctgcgcgc ccggggcggc accctgcgct gcggacggcg
     5701 cgtcagccgc gtcgtcgtcc gcgaccggcg cgccgtggcg gtgcgcaccg ccgacggcga
     5761 gaccgttccc gcgcgccacg ccgtgctcgc ggacgtctcc gtacccgacc tgtacggcgg
     5821 tctcgtcgag ccggagcacc tgcccgcaca ggtgctggac gacgtcgagc gcttccagtg
     5881 ggacttcgcc accttcaagg tggactgggc gctggacggc ccggtgccgt ggaagtccga
     5941 ggaagcggcc cgggccggca ccgtgcacct ggccgacggc gtggacgaac tgacccggtt
     6001 cgccgcccag atcgcgatgc ggcaggtgcc cgaccggcct ttcaccctgt tcgggcagat
     6061 gacgaccgcc gacccgtgcc gctcgccaca gggcaccgag tcggcgtggg cctacaccca
     6121 cgtcccccac gacatccggg ccgacgccgg ggaggagggc atcaccggaa gctgggacgc
     6181 cggggagcaa gagctcatgg ccgaccgcgt cgaacggcaa gtcgagcggt tcgccccggg
     6241 tttccggcaa ctcgtgcgcg cccgccgcat cctggccccg cccaccctcc agtcgctcga
     6301 cgccaacctg cgcggcggcg ccatcaacgg cggcaccacc gccctccacc agcagctctt
     6361 cttccgcccc gtgcccggcg ccggacggcc ggagacagcg gtggcgggcc tgttcctcgc
     6421 ctccgcgggc gcccacccgg ggggcggcgt gcacggcgcc cccggcgcca acgccgcgcg
     6481 ggccgcgctg cgccggcact tccccccggg ccgtacccgg ctccagcgga tgctcgccgg
     6541 ccgcgaccgc accggaacga aacggtgagc gggcggccgg cggtggacag ccccctgcgg
     6601 aaccggaccg tcgtcgtcac cggagccgcg cgcggcatcg gggcggcgct ggcgctggag
     6661 ctggcccgcc gcggcgcccg gctcgccctg ctcggccacg agaagcccct cctggacgcg
     6721 gtggcggcca ccgtgccgtc cgccgcactg acgtgggagg tggacgtcac cgacgccgag
     6781 gcgctggccg gcgcggcgga cgaggtgcgc cggcggctgg gccccccgtc cgccgtggtg
     6841 gcgaacgcgg gcatcgcgac cggcggcccg ttcgccacct cggacccggc cctgtggcgc
     6901 cgcgtcatcg acgtcaacct cacgggcagc gcccagaccg cgcgggcgtt cctgccggac
     6961 ctgaccgaca cggcgggcta ctacctccag gtcgcctcgt ccgcgtcgct gggcgccgcc
     7021 ccgctgatga gcgcctactg cgccgccaag gcgggggccg aagccttcgc ccaggcactg
     7081 cgggccgagg tggcgcacct cgggatcggc gtgggcatcg cctatgtgca ctggacggac
     7141 accgagatga tccgcgacgc cgaccggtac acggccctgc gcaccctgcg cgtccgcatg
     7201 ccgccgcctg cctcgcgcgt ctcccccgtg gacgcggtcg ccgcccggct ggcccacgcc
     7261 gtcgaacgcc gtcgtacgac cgtctacgta cccgcctggc tgcgcatggc acaggtggtg
     7321 cgcacggcca tgccccccgt ggtgctgcgc cggacccgcc gcgaactgcc ccggctggag
     7381 gacgcccggg aactgaccgc gaccggcccg ctcggggcgg gcggacgggc cgaccgggcg
     7441 gccgcggagg agacggcggg ccggcagacg ggggagacgg cggatccgaa gacggagaca
     7501 acgccggaca ccggcgaaag ggccgccaag gagacggacg gggagacgga cgagtaggcg
     7561 tcgtaccggg gccgtcgcga gtcgtccgcc cgcggccggg gaccgccggg gacgtcaggc
     7621 gcgcgatctt ctcttctccc tccccgccgt cgtgctcccg gtcacggtcg ccccgcggcg
     7681 ggcgagggcg cgcagcagcg ccgagcggcc gcggtcgggg accgtccaca gcccctcacc
     7741 ccgcacgccc caccgctcca gcagggcgtt ggcggcgagg aatccggagg tggcggcccg
     7801 ctccatcaac gccaccggca ggtcggtgcg caccagatca ccggcgacga cgacggccgg
     7861 gtccggcgtc cggacggtgg gccggtcccg gtagccgccc accgggaaca gcgggcagtc
     7921 cgcccggtat tcgtggcgga cgtcgaggac gcgggcgtca cgggtctccg gatacacgcg
     7981 gtgcaactgc tcggtgagtt ccccggccgc cgtgtccggg gcggtggcgg gggagagcgc
     8041 gtagccgtgc agttcgacga ccgatccgcc cgagcgcgcg gcccagcgtg ccgcctcgcc
     8101 ctcccagtgg gagaccacgc tgacgttgtc cagcgggccg tagccgctgg tgccgaggaa
     8161 tccggggcgg ccgggggcga ccggccggtc cagccacagc cgggacacca ggaacggtgg
     8221 cgcggtgcgc agccgcgcca cccgggcccg ccactcggcg tcgccgagcc ccggtgagcg
     8281 gtccaccagc gccctcaggc cgtcgacgtc cagggcgagg acgacggcgt cgtagcggcg
     8341 cgcaccggag gcgtcgacca cgtcgtggcc gccgtcggag cgcggacgga cggcctccac
     8401 gggggcggcg gtccgcaccg tcacgccgtg cccggccagg tggcgcgcga gcggatccca
     8461 cagcgcctgc ggatacggct cgcgcggaac gtcgaacagc agcccttcgc tggagccgag
     8521 gaagtagatg tggaacatca gcgccatctc cgcggcggac agctcacggg ggtcggcgaa
     8581 gaaactgcgg gagaacacct cgaaagccag gtgccgtgcg gcggcgggga agcgcaggga
     8641 gtcgaggaag tcgtgcgcgc tgacgtggtc gagccggtcg tggacgcggc gggtgcggac
     8701 gtcgagcagg ggcagcgccg ccgaggggcg cagggacagc aggtcccgag gcccgaaggc
     8761 ggggctcagc gcgacgaaac cgagggcgtt ccacggggga gtgcgcggaa cgcggcggaa
     8821 gccgtcgcac aggccgctgc tgtgccggag cgggtagtcg ggcagccccg ccagcatctc
     8881 cagcgcggga tcggcccggc gcagcagact ccgcaggttg tagtactggc ggaagaaggc
     8941 gtggaaaccg cggctcatcg tcgcccgtgt gccgtcggcc agggtgaccg gccggccgga
     9001 gacccggccg ccgagctgcg gctcgcgctc gtgcagcacc acgcgtacgc cgcgctcggc
     9061 gagcacggtg gccgccgcca gcccggcgat gccgccgccg accaccgccg cggacggcgg
     9121 cccgccggcg atccgctccc gtccgggccg gggcgggagg agccgcgcgc gccggtccct
     9181 gcccgggggg cgcgcgccgc ctcgcgcgct caccgggcac cgcccgggcg ctggggcggg
     9241 cggcgggcca ggaacgtgtg ggtgataccc gtctgccagc cgggcagcgg caggacgcgg
     9301 acgcggtcga acccggcccg gcccagccgg gcggcgaagg ccggcgccgt gtcgaaggtg
     9361 gcgacactgc gccccagatg gcggtagaga gcccggtcgc cggtggccgt gccgagcggc
     9421 cggatgacac cccggcagac cgcggaccac accaggcggt cggcccgccg tccgctgagc
     9481 gcgtactcgt gcaccgcgag gcggccgccc ggcgccagca gcccgcgtac cgtccgcagg
     9541 accgcgtccg ggtcggccag gttgcggaag agataggcgg cgaagacggc gtcgaacggg
     9601 cccgacaccc ccgcgcggct cagttcctcc gccggggcgt gcacgaagcg cacccggtcc
     9661 ggccacggct tggcccgcgc ccggcgcagc atgcccgccg aggcgtcgac cccgacgatg
     9721 tccgcgccgg ggagcgtcgc ggccagcgcc gccgtggacg cgccggtgcc gcagcccagg
     9781 tccagcaccc ggcatccgct gccgccgtcc ggcagcccca gccggcgggc ggagcggcgc
     9841 aactggccgt ggtaccccgg gttgagcgcg accagacggt cgtaggcgcc ggcgccgtga
     9901 tcgaaggcgt cggccagcgc cgcgtcacgc agcaaggtca tcggtgactc ctgaacgggg
     9961 gtggggcgcc gggagcgacg ggggaggcgg gcgtcgccgg tcatggggcg ggagggcgga
    10021 cgcggcgggg cagccagggc acctcggccg ccgtccgcag catcggcagg acgggggtgc
    10081 gcacgccgac cgagagatcc tcgtacagcc gggtctcacc gtcgaggaag cgcagcagta
    10141 gccgtacggg tacgcgtgcg aagagccgga agaagaagtc ggggccgtcg atccggcccg
    10201 tgtccagcgc gcgcagcagc acggcgtcca tcatccgggc acgcgccggg tgcggtggcg
    10261 gcggtacggg tgccctgccc gcgcggaccg ctcgcgcgac ggcgtccgac tgccgctgca
    10321 cggcggagaa ggtgtaaccg gtggcggcgc gcgtcgcccc gcccgcggca ccgatcggga
    10381 agacggagcg ggcgatccgc cgggggaaga cggcgtcggt catcgggatc accccttgct
    10441 ccgtcgacag cacccgcgcg tcgccgatgc cgaggacgcg ccgtgtgtag tgctccaggg
    10501 cggcgtcgta ggcgtcggcc gtgagcgggg cgggaccgaa ctcggtgtac tcgaccaggg
    10561 cggttcggcg gccggtgggc aggacgtatc cgaaggacag gccgcgggcg ggctgcgggg
    10621 tgcggaagtc catcaggtcg accacctccg ggtcgaacgc cggccgggag gtgcgcacga
    10681 accagccccg gaagtgctgg agcagacggg tgcgggcggc gggcgggcgg ggcggtgggc
    10741 gggagtcgaa gacccaccgg ccgcgcagcc ggaccgggac gcccgcggcg tccgtgcccc
    10801 ggacctcggc cgtcccgtcc ggcaggacgg ccaccgtgtc gacggcggcc tccacacggc
    10861 gcactccggg cgccttgccc agatcgccgg tgaccagggc ctcgaagtcg tccgaacgga
    10921 tcatcttgta gcgcaccggc gcgatgtgcc gccggacggc ggctccgtgc cggtcgcgga
    10981 cccgcagcca ctcccacgac gccgtcaccg ccgggtcgaa gcggcccgcg cccgtctccc
    11041 agaaacacca ggtgcggcgc ggcgcccgca gcggaccggc gggcggctcg accaggacga
    11101 ccgagggcgc cgcacggtgc cccggcgccg cggtcggcag ccggtgcgcc agcgacaggc
    11161 ccgccgcccc ggccccgacg atgacgatgt cggcctgcag tacggcgtcc gcccgccgcc
    11221 cggcgcccgt ctccagcacg gccgttctcc tctcctgcgg tctcctccgg cgccccgcgt
    11281 ctcactccgg ggccttgcgg cagtcctcgg gaccgggagc cctgcggccg gtcgcccggc
    11341 ggtcctgccg ggcccgggtc ctcagctccg gtgcgaggac ggcccggaca cgcccggatg
    11401 ccggccgcac cacccggatg ccgtccggac ccggccggat cccagccgta ttcggccgga
    11461 cgcccgtccc gcatccgggg caggcgtcgg ccgagtattc cccgcgcggc cggctcccgg
    11521 acgtacggcg cgcgggaggc gaccgggccg ggtgcccgcc ggacgggtgg ccgacgcgca
    11581 gaacgggcga ctgcggcttc gggccggacc ccgccgggga aggcatgagg ccgtgcctcg
    11641 cggcgacgac gccgggccgc ccaccggcac ggtgcggaag gcgtgccgtg ccctccgacc
    11701 gggtgccgtg agcggcacgc cgccgacgcg ggacgcctcc ggcacccccg gtcgcccgca
    11761 tgccccgacc ggaccttcgc ggcccggacc cacgacagac gaccgaccac cgacgaccga
    11821 ccaccgacga ccgacgagag gaaccgggat gcgacccagc ggagctaacg gcgcccgccg
    11881 tgcccggggg cgaccaccgg gagccgccgc gcacgccacc gctcggagcc ggccgcgccg
    11941 gaacggcccc gccccggccg cgggaaaggg ccggagatga cccggaccat gcccggccgc
    12001 accgaccacg tcgtgatcgt cggggcgggg ctcgccgggc tgtcggccgc cttgcacctg
    12061 ctgggcgccg ggcggcgggt gacggtcgtg gagcgggacc ggctgccggg cggccgggcc
    12121 gggcgccgtg aactcggcgg atatctcctc gacacgggcc ccaccgtgct gaccatgccc
    12181 caggtggccg acgaggcgtt cgcggccgtc ggcgagcggc tgcgggaccg tgtcgagctg
    12241 ctgccgctgc accccgccta ccgggcctgc ttcgccgacg gcagcaccct cgacgtgcac
    12301 accgacgcca ccgccatgga agcggaggtc gagcggttcg ccggccctcg cgaggccgcc
    12361 ggataccgcc ggctgcgcac ctggctgacc cggctgtaca ccgtgcagat gcgccgcttc
    12421 atcgacgccg acttcgactc gccgctggac ctgctcaccc ccgacctggc ccggctcgcc
    12481 gcgctcggcg ggttcggccg gctcgacgcg cgcatcgggc ggttcctgac cgacgagcgc
    12541 ctgaagcggg tgttctcctt ccaggccctg tacgccggtg tggcaccggc ccgggccctg
    12601 gccgcctacg ccgtcatcgc gtacatggac accgtggcgg gcgtgtactt cccgcgcggc
    12661 ggcatgcacg ccctgccgcg cgcgatggcc gccgctgccg ccgacgcggg gggcgacctg
    12721 cgcttcggcg aggaggtcac ccacctggag cggtccggag accggatcac ggccgtcgtc
    12781 accgcccacg accgcatccc ctgcgacgcc gtcgtcctca cccccgacct gcccctggcg
    12841 caccggttgc tgggccgccg gccgcgccgc ccgctcccgt tgcggcacgc gccctcggcg
    12901 gtcgtgctgc acgccggcac cacccgcacc tggccccatc tcgcccacca cacgctctcc
    12961 ttcggcgccg cctggcagcg cacgttcgac gagctgaccc ggagcggcac cctgatgacc
    13021 gacccgtccc tgctcatcac ccgccccacg gccgcggacc ccggcctcgc ccccgaagga
    13081 cggcacctgc actacgtcct ggccccctgc cccaacaccg acatcgggcc cggcccggag
    13141 gcgtggcacg ccctcgcccc ccgctaccgc gaccgcctcc tcgccaccct cgaccgccgg
    13201 ggcctgtccg gtatcgccgc cgccatcgag gaggagtgcc tggtgacacc cgccgactgg
    13261 accgcgcacg gccacgccgc gggaacgccg ttctcggtgg cccacacctt cacccagacc
    13321 ggtcccttcc gcccccgcaa tctggtgcgc ggcctgcgca acgcggtcct cgccggctgc
    13381 ggcaccacac cgggcgtcgg catccccacc gtcctgatct cgggcaagct cgccgccgcc
    13441 cgcgtcaccg ggcccccggc ccgtccgcgc cgccccgtgg aggccgcacg ccgatgaccc
    13501 agcgcgaact cgacgccgcc ggcatcaccg atcccgtgct gcgcgccgcc tacgcccggt
    13561 gccgccggct caacgcccgc cacggacgca cctacttcct cgccacccgg ctgctgcccg
    13621 ccgcacgccg gcccgccgtg cacgcgctgt acggcttcgc ccgcttcgcc gacgacatcg
    13681 tcgacgacct cggcaccacg gtcggccgcg ccgaacgcgc cgcggccctg gcccggctgg
    13741 aggagcggct gcggcaggca ctgacgggcg ccgcccccgc caccgaaccc gtggtgcggg
    13801 ccgtggccga caccgccgcc cgctacgcca tcgacccggc gcacttcacc gacttcatgg
    13861 cgtcgatgcg cagcgatctg acggtcacct cgtacgcgac ctacgacgac ctgcgcgcct
    13921 acatgcacgg ctccgccgcc gtgatcggcc tgcagatgct gcccgtgctc ggcaccgtca
    13981 ccccgcgcgc cgaggcggcc ccgcacgccg cggccctggg ggtcgcgttc cagctcacca
    14041 acttcctgcg ggacgtcggc gaggacctgg accgcggccg cgtctacctc ccggcggacc
    14101 tgctggccgc gcacggcgtc gaccgggacc tgctgcggtg gagccgccgc accggcgccc
    14161 acgatccgcg gatcaccgcc gccctgaaag ccgccgagaa cctgacccgg gaggtctacc
    14221 gcgaggccgc gcccggcctg gcgatgctgg acccggtggc gcggccgtgc atccgcgccg
    14281 cgtacgtcct ctaccgggac atcctcgacg ccatcgccga gggcgggtac gcggtgctgc
    14341 accggcgcgc ggtggtgccc gcccgccgcc gcgccgccgt ggcggcgggc gggctcgccc
    14401 gggtcctggc cgcccggctg cgggccgggt accccccggt ccccgccacc gccccggccc
    14461 ccgccgccgg caccgccccg gcccccgccg ccggcaccgc cccggcggac gggccggtgc
    14521 cccgtcccga ggggacgagg gaggccgccg gatgacagcc gggaacaacg cccgccccgg
    14581 accgcgcgcg ggtctctccc cgctgcggct gcgccggcgg cccgtcccct gggagcggca
    14641 ggacccgacc tggcggcagg cacggcccgc cgccatcacc ggcgccctga aacgggcgct
    14701 ggcccgtccc tcgggcaact ggtacgtcgt cggcgccgcc gccggcgtac ggccggaccg
    14761 cccgctgggc cggaccgtcg cgggcgtgga agtggtcgtc tggcgggacg cgcgcggacg
    14821 cctggtgggc ggtccgggcg cctgccccca cctcggggct ccgctggccg ccagtccggt
    14881 gcgctgcggg accctcgtct gccactggca cggactggcc ctggacggga ccgcgttcgc
    14941 cgggtgggag cccctgccgg tccacgacga cggcgtgctc gtatgggtcc ggctggacgc
    15001 cgtcggccgg gaacgcccca cccccgcccc ggtgctgagc ccccggcccc cgctgccggc
    15061 cgctctcgtc tccgtctggg agggcgtggg ccggtgcgca cccgaggacg tggtcgccaa
    15121 ccgcctcgac ccgtggcacg gcgcgtggtt ccacccgcac tccttcgccg acctcaccgt
    15181 ggtgcgggaa cccggggccg gcgagccggg cgccggcgac gccgacgacc ggttcgtcgt
    15241 cgacgtgtcc ttccggctca cccgccggct cgtcgtcccc gtgcgggcgg agttcaccgc
    15301 gccggaaccc cgcaccgtgg tcatgcgcat caccgacgga gagggcacgg ggtccgtcgt
    15361 cgagacccac gccacgcccc tggccccgga cggccgcggc acaccccgca cggccgtcgt
    15421 cgaagcggtc ctcgccacct ccgcccgccc cggcttcgcc ctcgcccgcc ggctggcccc
    15481 ggcgctgcgc cccctgatgc gcaccgccgc cgcccggctc tggcgcgacg acctcgccta
    15541 cgccgaacgg cgccggcacc tgcgggacct cggccggcac cccggctgac caccggcccg
    15601 gcccggccgc gcggcgtcac cgcgcaccgg ttgccgcggc gcgggaccgc caccagactc
    15661 gcacgaggac ggtggcgtcg ttcacgcacc gcacgcaccc tgcgcgagga ggtcccgaga
    15721 tggccaggaa cagcggcaag gacggcagcg ggggcaggaa gcgaggcggc gggaagggcg
    15781 gcgggaagga cagggccgag ggcgggacgc cgggcggcgg cgagcggtac gccgaaggcg
    15841 acagggtggc ctggaacagc cacggcggca gcaccgaggg catggtcgag cgcgagatca
    15901 cccggcggac cgaggcggcc ggccgcacgg tggacgccgc tcccgacgca ccgcagtacg
    15961 aggtgcgcag cgacaagttc ggcaagcggg cggtccacaa gccgtccgcc ctgcggaaga
    16021 aggacccggg cgcgtaggga cgacgatcgt gcagacgttc ctgccccacc ccggcttccg
    16081 cgactcggcg ctcgtcctgg accgccggcg gctcggcaag cagcgggtcg aggcgctcca
    16141 ggtcctgcgc gggctgaccg tgccgggcta cggctggcgc cggcaccccg cggtgcgcat
    16201 gtggaccgga tacgaggagg cgctggtccg gtacggcctg gaggtctgcc gggtctggcg
    16261 ggaacgcggt caccaggaca gttgcgccgc ctccctcgtc gccgggctgg agacctggtg
    16321 tcccggcacg ccggtgcgcg accagagcgc gctcgccgag gccggcgaac tgccgccctg
    16381 gctcggcgac gacgccttcc accgcagcca ccgctcggcg ctggtccgca aggatccggc
    16441 cgcctacgcc gagctcttcc ccggcgtccc cgacgacctg ccctacgtat ggccgtcctc
    16501 ggaccgcgag cgcggggaga ccccggcgga ccggtgagcc ggcgcccgcg ccgcgtcccc
    16561 gtacccgccc ggtccgccgc gtccgacgcc cggggggcgg acaggtccgc ccgcacatga
    16621 cggacacttg tggtatggac ggggaaccgg ccgccgtggc ggcggcccgt gagcgcctgg
    16681 gcagcgccct gttccgccgg gtcgccggac cggagggccc ggccaaccgc gcccgcatcc
    16741 acggcacgcc cggcccccgg tggttcggcc ccgaccgccc cgtccgcgtc gtgcacggcg
    16801 acgcgtcgat gttcgtcggc ggcatacgcg ctctgctgct ccagtcgctg catccgctgg
    16861 ccatggccgc cgtcgccgcg cactccggtt accgcggcga cccctggggc cgcctgcagc
    16921 gcaccagcac cttcctcgcc gtgacgacgt acggcaccgc cgacgacgcc cagcgggcgg
    16981 tcgaccacgt ccgcgccgtc cacgagggca tacgcggcac gacggccgag ggcctgccgt
    17041 accacgcggc cgacccgcac ctgctgaagt gggtccacct ggccgagacg gacagcttcc
    17101 tgtgcgccca cgaacgctac ggcgcccacc cgctggacgc cgccggctac gacgcctacg
    17161 tcgccgacac cgcgcgcgtc gcgacggccc tgggcgtact cgatccgccg cgcacccgcc
    17221 gggagctggc cgggcagctg gccgcctacc ggcccgagct ccgggccacg ccccaggccc
    17281 gcgccgccgc gcggttcatc ctgttccagc cgccgctgcc gctgcccgcc cggcccttct
    17341 acacggtgct cgccgccacc gcggtcgcca ccctgccgcc gtgggcgcgc gcaccgctcc
    17401 gcctgccccg cctcccggtg gccgaggacc tcgccgtccg gccggccggg caggccctgg
    17461 tccgggccgt tcgctgggcg atgacgccgc caccggacct gcccggctga ccccgccgat
    17521 ggggtgccgg gcgggaggag agggaacgcg gcggctcacc ccggcccggc gtcccggccc
    17581 gcggcggccg cccgggcgat gttgcgcgcc atgccgccga acaccacggc gtggaagggc
    17641 gagacgcccc accagtacac gtggccgagc agcccgtgcg ggtggaacag ggcccgctgc
    17701 cgatagcggg tacggccctc gccgtcggtc tcgacgtaca tctccagcca ggccagaccc
    17761 ggcagccgca tctcggcgcg cagccgcagc agccgtcccg gctcgatctc ctccacccgc
    17821 cagaagtcca gcgagtcccc gacccgcagc cgtgccgggt cccgccgccc gcgccgcagc
    17881 ccgactccgc cgaccagccg gtccagcagg ccccggaccg cccaggccga cgggaaggag
    17941 taccagccgc gctcgccgcc gatgccctcg atcacccgcc acagcgtccc cggcgaggcg
    18001 tgcacggtcc tggaccggtg gtcggtgtag aggctgccgc ccgcccagtc cgggtcggtg
    18061 ggcagcgggt cgctgggggc gccgggcacg gaggccgacg accagcgggt ggtcacccgg
    18121 gcctcccgga cccgctggag ggccagccgg acggcctcgt cgaagccgat cgggtggccg
    18181 ggcggatcgg gcacgtaccg cgcgatgtcg tgctcgcggc agacgacctc gtggcgcagc
    18241 gattccgtca gcggccgcgc gatggccgcg ggcaccggtg tcaccaggcc cacccagtgg
    18301 ctggacaggc cgggggtgag gaccgggacg ggcacgatca gccggcgcgg gagtcccgcg
    18361 accgccgcgt accgggccat catgtcgcgg tacgtcagga tgtccggccc gccgatgtcg
    18421 aaggcgcggc tgacgtcgtc cggcatgcgc gcgctgccga cgagggcgcg cagcacgtcg
    18481 cggaccgcca ccggctggat ccgggtgcgc acccagctcg gggtgaccat caccggcagc
    18541 cgctcggtga ggtagcgcag catctcgaag gaggccgagc cggagccgat gacgaccgcc
    18601 gcgcgcagca ccgtggccgg caccccgcag tccagcagga tgcggccgac ctcggcccgg
    18661 gaccgcagat gcggcgagag cgcggcttcc ggcaccccgg cgggggtgag accgcccaga
    18721 tagacgacgc gccgcacgcc cgcctcccgg gcgcgctcgc cgaagatccg ggccgcccgc
    18781 cggtcggtct cctcgaaacc gcgtcccgtg cccagcgcgt gcaccaggta gtaggcgacg
    18841 tcgacgccgc gcagggccgc ggcgagcgac gcggaatccg tgacgtcccc gcgcaccgtc
    18901 tccacctcgc ccgcccacga ctggtcccgg agcctgccgg gggagcgggc cagacagcgc
    18961 acccggtggc cctcggcgag cagctcgggg accagccgcc cgccgatgta gccggtcgca
    19021 ccggtcacca ggcagtgcag ccccgccgcg gtgtcgtcac tcatgtccgg cctctcgtac
    19081 ggggacctgt ccgccgatcc ctacccggcg gacggcgggg gtggacgcgg ccgtactccg
    19141 tccggagcgc ctggcgcacg cggtggccgt cccggccggg gaggggaggc cgggagcggg
    19201 gccgggccgc ttctataggg tgctcacgtg atcagtgcgg acggccggga cggccgggaa
    19261 caggagcgga gcgcccaggg gcgcggggcc cgggacggag aggcgggcga gcggccggcg
    19321 gcgactgctc tggcctcctt cgccgtgcag ttgcggcgca tgaacggcga gatcaaccgt
    19381 ctggcgcacg gattcgccgg cgagcacggc ctgcacgcca ccgacgtcca ggcgctggcg
    19441 gcgatcctcg acgcggagga accgatgacg cccggacggc tgcgcgagta cctcggactc
    19501 agctcgggcg ccgtgacggc gtgtgtggac cgcctggaac gggcggggca catccgcagg
    19561 gtccgcgaga gcgccgaccg cagggtggtc cacctgcggt acgcgccgga cgcccggcag
    19621 acggcccgcg cctacttccg tcccctggcc gaggccacgg cctccgcgcg gtcccgcttc
    19681 agcgaggagg agctgtcggt ggtcgtgcgc ttcctcgact cgctcaacga ggaactggcc
    19741 ctgctgaggt ccccgcgagg ctgacccggc gccgccgcgc cgcgcgcccc gtgcgccgcg
    19801 cgcggcgtgt cccggtcccc cgcgacgggg gagatacagg tgtcgtctac gatcggcgca
    19861 agatatctcg atgatcgaga tactttgtcg tcgagtttca tcgcgtttcc cttccgctct
    19921 cccgtgacgc ctggagaacc atgtccgcac ccccctcgca cacgcgccgg acccgtctgc
    19981 tcgtcccgtt gctgctgctc ctgacctggc tcgtcgtggg cgggaccctc ggcccgttcg
    20041 ccggacggct cggcgaggtc gccaccaacg accaggccgc cttcctgccg cgcagcgccg
    20101 agtccaccga ggtcatcgcc gcacagcggg ccttccggca ggacgagagc ctgcccgccg
    20161 tcgtcgtgtg gaccttcgac gcggcggccc gggacgggca gggggcggcc acccgggccc
    20221 tcgcctcgct caccggcacg cccggtgtgg cgggccgccc ctcacccgcg ctggtctccc
    20281 gcgacggtac ggcgctgcag ggtgtcgtcc ccctgcgaac cgacctgggc gaccggctgc
    20341 ccgacgtcct ggaccgcgtc cgcgacgccg ccgagcgggt accgggcgcg acggtccacc
    20401 tggccgggcc cgccgcttcc caggccgacc tctccgacgc cttcgcgggg atcgacggac
    20461 tgctcctggc cgtcgcgctg gtgaccgtcc tggtgatcct gctgctcgtc taccgcagtg
    20521 tgctcctgcc gttcgtcgtc atcctcggcg cggtcttcgc cctgggcctg gcctgcgcga
    20581 tcgtctacgc gctcgccgac cacggggccg tccgcgtcga cggccaggtg cagggcatcc
    20641 tctccatcct ggtcatcgga gcggccaccg actacgccct gctgctgacc gcccgctacc
    20701 gcgaggaact cggcgtgcgc ggcgaccgtt tcgcggccgt acgcgccgcg ttgcgggagt
    20761 cctggggcgc catcgtggcc agcgccgcca ccgtggcgct cggcctgctc gccctcctgc
    20821 tgagcgacct gaccaacaac cgggcgctcg gcccggtcgg ggccatcggc atcgtctgcg
    20881 ccgtactgag cgccctgacc ttcctgcccg ccgtcctcgt cctcctcggc cgcgccgcct
    20941 actggcccgc gggcgcccgc gccgcggggg agcggccggg tgtgtggcac cgcgtcgcgc
    21001 acctggtgga ccgggcgccg cgccgggtgt gggccgtcgc gctggcctgc ctgctcgcgg
    21061 gtgccgcctt cgccccgtcg ctgacgtcga agggcgtgcc gctggacgag acgttcgtcg
    21121 gcgacgcgcc gtccgtggcg gcgcagcgcg tcctcggtga gcacttcccc ggtggcgccg
    21181 gaaatcccgc cgtggtgatc gcgaacgccg accgcgccga gcaggtggtg gcggctgccc
    21241 gggacacccg gggcgtggcc ggtgccgtgc ccgtcaccgc ctccggaggc ccgggcgagg
    21301 gcgagccgct gaccgtcggc ggccgggtgc gcatcgacgt caccctgcgg gccgccgccg
    21361 acagcgacga ggccagggag accgtggccc ggctgcgcgg cgccctgcac gccgtgccgg
    21421 gcgccgacgc cctcgtgggc ggctacacgg cacagcgcca cgacaccctc gagacggccg
    21481 agcgggaccg taccctcatc gtcccggtcg tcctcggcat catcttcgtc atcctcgtcg
    21541 ggctgctccg gtcgctgctg ctgccggcgc tgctggtcgt caccgtggcg ctgaacttcc
    21601 tcgccaccct gggcgtctcg gcgctcgtct tccggcatgt gttcggcttc acgggaacgg
    21661 acccgtccgt gccgctgtac ggtttcgtgt tcctggtcgc gctgggggtg gactacaaca
    21721 tcttcctgat gtcccgggtc agggaggaag cgctcgcgca cggcgtgcgc cgcggcatcc
    21781 tgcgggggct cgtcagcacc ggcggggtga tcacgtcggc gggtgtggtg ctcgccgcga
    21841 cgttcgccgc cctcggggtg atcccgctgg ccttcctcgt gcagatcgcc ttcatcgtcg
    21901 cgttcggggt gctgctcgac accctggtcg tacggtcgct gctggtcccc gcgctcagcc
    21961 gggacatcgg ggccgccgcc tggtggccgg ggcgcctctc ccgcgcgccg gggaggtgac
    22021 gggagcgcga cgcctccggc cgccgggcgc ggcccgcacc cggcgggacc gcgccccggg
    22081 gccgccgagc tccctaccgc gcggcggagc ggtcctcgtc gaagtggtag agctccctgg
    22141 acgtcctgat caggtcccgc agctcctgcc gcgaaccgac catcggctgc gagccgttga
    22201 gcggcacctg ggcgctctcc ggcaggaacc gcaccgtcac cagcccgatc agcccggccg
    22261 ccatcagata gaaggccggc accagatcgt tgccggtggc gttcacgagg gcctcggtga
    22321 ccagcggtgt ggtaccgccg aaggcggcga cggcgaagtt gaagccgatg cccatggccg
    22381 cgtaccgcac ggcggtgggg aagagcgccg gcagcgtggc ggcgctcggc gcggcgaagc
    22441 aggccaacag ggtggacagc accagcacgc cgacgacggg ctgccaggtg ccgtccgcct
    22501 tcagcagcag gaaggccggg accgcgagga cgatcatcgc ggcggcgccg accgcgtaga
    22561 gcgggcggcg cccgacgcgg tcgctgagcc gcccgaggaa ggtgatcagc aggacgatcc
    22621 acaccatgcc gatcagcacc agcaggtcgg cgaagctggt ggagcggccc acgttctccg
    22681 tctggtaggt cggcaggaag ccggtgacca tgtagttggt gacgttgtag agcaggacca
    22741 ggcccatgca gaccaggagc ggacgccagt gcctgcggat gatcgtcttg aactcgctgc
    22801 ccgccgatgc ctgggcgagg ctcttctcgt gttcgtcgag ctgcttctgg aaggcgggcg
    22861 actcctccag cttcagccgc atgtacagac cgatcaggcc gagcgggccg gcgatcagga
    22921 acgggatccg ccagccccag gagagcatct cggcgtccgt gagcgccagg ttcaacacgg
    22981 tgaccagcgc cgagccgagc gcgtagccga cgaaggtgcc gaagtcgagc cagctcgaga
    23041 ggaagccgcg ccgccggtcc ggtgagtact cggcgacgaa cgtggtggcg ccgccgtact
    23101 cgcctccggt cgagaagccc tggaccatgc gggcgagcag cagcagggcg ggggccgcga
    23161 tgccgatgct cgcgtagccg gggatcaggc cgatggagaa ggtgccgatc gccatcatga
    23221 tcatggtggt ggcgagcacc ttctgccggc cgatgcggtc tccgaggggc ccgaagacca
    23281 ggccgccgag cggacggacg acgaaggccg cggcgaaggt cgcgaaggag gagatcaact
    23341 gagcgcccgg agacgcgccg gggaagaaga ccttgccgat ggtggcggcg agatagctgt
    23401 agacgccgaa gtcgaaccac tccatgcagt tgccgagcgc ggaggcgccg accgcgcgct
    23461 tgagcagggg ccgttcgacg acctggacgt cctcctcgcg gaaggcccct ttcttccggt
    23521 ggagccggcg cgacagctcc tcgcggacct gccgcggcat gtcggcgacc gtcttcggca
    23581 ccgtcgcccg gccgcgcgga ccgggccgtc cgtcgggcat cgcgtcgctc acgctgccgc
    23641 ctttctgtcg ctgcactctc ttcgcctatg cgaattctgc gcctcggtga tcatggggcg
    23701 catgtcaggg ctgctgcccg ggttcgcacg cggcacacac cggaggcatg tccggtaggt
    23761 cacgaaagcg gcggcgtgga ggcggtgggg gtgcggacgc ggcggcggtc cccgcacccg
    23821 gcggcagggg ggcacgggga ccgccggggc tcgcccccgg cccgggcgcg atcggctccc
    23881 ggaccgggcg cgatcggctc ccgggccggg ctcggccggg cacggcccgg ggtgcctgcc
    23941 cgcgcccggc ccggggcgag cccggaggcg gggttacggc agcagaggca gcgtccggca
    24001 gttggcggcg gccggctcgc ccgacagccg gtccgtgagc caggagatcg cgtcgccctg
    24061 gtcggtcagc agcggcccga agtggttgag cagcccccgg ccgacgtcgg gcaggaccac
    24121 cggggcgtag gtgacgttcc cgcccagccg gcaccagtcg acggccatcc gccgggactg
    24181 ggcgtgcggg accagatcgt cgttgacgcc ggtggccacc cggaccgggc cgctgggctt
    24241 cagcgtgccg atgcgctgct tgccgaggaa cgtccgcagg gtgggctcgg ccgcgatgat
    24301 ctcgccgagc gactgccccg tggtggtcca cgccgtactg cgggaggacc cgtacgcgaa
    24361 cagcgcgtcg ccgacgcacc gggtggacag gtccgccagg gcctcgcgcc ccgcgtcgtt
    24421 gaggtaccgg tcggcgatgg gccgcaggga cggctcggtc tgcaggaagc cgttcagcga
    24481 ccagcccagg gctcccgcca ggtcgcttcc gtcgatcgcc ccggtgacct cggtcaggtc
    24541 cgcgggcgga gctcc
//
