LOCUS       NZ_LN831790            21029 bp    DNA     linear   CON 08-APR-2024
DEFINITION  Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 =
            NRRL B-24963) chromosome 1.
ACCESSION   NZ_LN831790
VERSION     NZ_LN831790.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces leeuwenhoekii
  ORGANISM  Streptomyces leeuwenhoekii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Gomez-Escribano,P.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2015) JIC, Department of Molecular Microbiology,
            Norwich Research Park, Norwich, NR4 7UH, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001013905.1-RS_2024_04_08
            Annotation Date                   :: 04/08/2024 03:45:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,096
            CDSs (total)                      :: 7,005
            Genes (coding)                    :: 6,806
            CDSs (with protein)               :: 6,806
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 82 of 199
            Pseudo Genes (incomplete)         :: 160 of 199
            Pseudo Genes (internal stop)      :: 10 of 199
            Pseudo Genes (multiple problems)  :: 49 of 199
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:33:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 598794
            Orig. end                         :: 619823
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LN831790.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21029
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21029
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21029
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11029](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11029
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            42..737
                     /locus_tag="BN2145_RS03990"
                     /old_locus_tag="ABM27_RS03905"
     CDS             42..737
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027343.1"
                     /locus_tag="BN2145_RS03990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03905"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_029384826.1"
                     /transl_table=11
                     /translation="MANTSPSVRRTALLASAVAALGALTACGTDGAATGATTSAVTGGT
                     AGTARQSPATGTPPGTAVSSPAGSVERSPSRAVPSDTAGSASASARSDGRCHTSELRAS
                     VGRVDPGAGQRNFPVVLTNISSRTCTLYGYPGAAFTDSSGRQVGPDPRRAPGSPETVTL
                     APGRSAWAGLSFASPDVSGARAATPAVLLVTPPDERDSLRVEWKGGKVPVGGTASTVSV
                     TVLDTGTGP"
     gene            complement(808..1776)
                     /locus_tag="BN2145_RS03995"
                     /old_locus_tag="ABM27_RS03910"
     CDS             complement(808..1776)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978092.1"
                     /locus_tag="BN2145_RS03995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03910"
                     /product="aldo/keto reductase"
                     /protein_id="WP_029384827.1"
                     /transl_table=11
                     /translation="MQYVKLGSTGLDVSRICLGCMTYGVPDRGVHEWTLDEEAARPLIR
                     QALEAGVTFFDTANIYSDGTSEEIVGRALRDFARRDEIVLATKVHYRMRPGPNGAGLSR
                     KAIMTEIDHSLRRLGTDYVDLYQIHRWDAHTPIEETMEALHDLVKSGKVRYIGASSMYA
                     WQFSKAQYTARLNGWTTFVSMQNHYNLLYREEEREMLPLCADQGVGVLPWSPLARGRLT
                     RDWGTTTGRSATDTFGSTLYQEGDRAIVEAVTRIAADRGVPRARVALAWLLHQDTVTAP
                     IIGASKPQHLDDAVAAVELELTDEEIEELERPYTPHPVAGH"
     gene            complement(1851..2384)
                     /locus_tag="BN2145_RS04000"
                     /old_locus_tag="ABM27_RS03915"
     CDS             complement(1851..2384)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994871.1"
                     /locus_tag="BN2145_RS04000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03915"
                     /product="flavoprotein"
                     /protein_id="WP_029384828.1"
                     /sec_met_domain="Flavoprotein (E-value: 1e-10, bitscore:
                     40.2, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEQDAKPFLYVVVCAAGVAADVGTLIAAAHRRGWEVGVIATPTA
                     AADGFFDTAAVEESTGRPVRAGARRPGDPRPFPPPDAVIVAPATFNTLNKWAAGIADTL
                     AVGTLCEAYGLGVPLAVLPCVADALAAHPAYQESVARLRAMGVRFGDPYTGEPGKGAGR
                     REFGWERALDLLDG"
     gene            complement(2394..2852)
                     /locus_tag="BN2145_RS04005"
                     /old_locus_tag="ABM27_RS03920"
     CDS             complement(2394..2852)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134804.1"
                     /locus_tag="BN2145_RS04005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03920"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_029384829.1"
                     /transl_table=11
                     /translation="MTARPPLPPFTRETAALKVQAAEDAWNTRDPHRVALAYTRDSVWR
                     NRDTFLTGRAAIVEFLTRKWQRERDYALRKELWAWEGNRIAVRFQYESRDAEGRWWRSY
                     GNELWEFDEHGLMARREASIDDVPIEEGERRIRGPRPETERGRPFPLQ"
     misc_feature    2876..2889
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.95"
                     /tool="antismash"
     misc_feature    complement(2898..2914)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.81"
                     /tool="antismash"
     misc_feature    complement(2911..2924)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.6"
                     /tool="antismash"
     gene            2947..3498
                     /locus_tag="BN2145_RS04010"
                     /old_locus_tag="ABM27_RS03925"
     CDS             2947..3498
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995700.1"
                     /locus_tag="BN2145_RS04010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03925"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_029384830.1"
                     /transl_table=11
                     /translation="MDIEVARERALDAAETLFYGRGVQCVGMDDIRAASGLSLRRLYQL
                     FPAKEQLVAAYLERRDVRWRGRLAQYTGRYAEPRRRILAVFDWLERWFGEPDFRGCAWI
                     NAHGELGALSPLVAERVRAHKRAFGRFLDELVAGAGLPAPLGGQLFLLAEGAMVTAGIT
                     GSAEPAARAREAARALLAAR"
     gene            3629..4288
                     /locus_tag="BN2145_RS04015"
                     /old_locus_tag="ABM27_RS03930"
     CDS             3629..4288
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019886.4"
                     /locus_tag="BN2145_RS04015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03930"
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_107409015.1"
                     /transl_table=11
                     /translation="MAGGAPEDEAVLAESVGLALLVVLNELGPAERVAFVPHDLFGVPF
                     DRIAAVTGRSRPAAKKLATRARAKVRGVPVLPGAELERHRQVVEAFPGAARGGDLAALL
                     DVLAPDVVRRADPVAVPPGGPVELPGARAVVEGTLLLRQRARSTALALVDGTVGAVVAP
                     RGRLVCALRITVADGRVASYEVVAEPERCRPLGLAVLDLPPRTAPGHALAAAHDGN"
     gene            complement(4475..5392)
                     /locus_tag="BN2145_RS04020"
                     /old_locus_tag="ABM27_RS03935"
     CDS             complement(4475..5392)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994866.1"
                     /locus_tag="BN2145_RS04020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03935"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_234342311.1"
                     /transl_table=11
                     /translation="MLVALAANLVIAVAKAAGGFLAGSPALLSEAAHSVADSMNEVFLL
                     AALRRSRRPADRRHPFGYGKERFFWSLLAAVGIFVMGGCFSFYQGVEALRGGAAEELGG
                     YVAGLVVLGVALLAEGASLLRALYQVRHQGGSRGLRDPALRTVVAEDGTAVVGVTLAIA
                     GMVLHMATGQVVWEACASLAIGTLLVYVAYRLGREARDQLIGEAADPEASGRIRALLQA
                     QPEIDSVEALFTMKTGLDSALVAARVDLVPGLDSERVEEVAVRIKRSIAHTVPEARQIF
                     LDVTDRPAQEARESPAATGERGGA"
     gene            5738..6763
                     /locus_tag="BN2145_RS04025"
                     /old_locus_tag="ABM27_RS03940"
     CDS             5738..6763
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978084.1"
                     /locus_tag="BN2145_RS04025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03940"
                     /product="glutathione S-transferase C-terminal
                     domain-containing protein"
                     /protein_id="WP_029384833.1"
                     /sec_met_domain="GST_C (E-value: 1.9e-05, bitscore: 23.4,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGDGGGGGNRAYGRKTFKRSRSHFADRITADGRDGWPVEPGRYR
                     LVVSRACPWAGRAVISRRLLGLEDALSLAIADPVQDDRSWRFTLDADGRDPVLGIRYLG
                     EAYDKRETGYPGGVSVPAIVDVPSGRLVTNDYQQITLDLATQWSALHRPGAPDLYPPAL
                     RDEIDSVMAEVYEDVNNGVYRAGFATGQREYEAACTAVFERLELLARRLERRRYLVGDT
                     ITEADIRLFTTLVRFDAVYHGHFKCNRWKLTENRVLWAYARDLFQTPGFGDTVDFDHIK
                     RHYYQVHTGINPTGIVPLGPDLSGWLTPHHREELGGRPFGDGTPPGPVPAGERVPARGR
                     P"
     gene            6849..7151
                     /locus_tag="BN2145_RS04030"
                     /old_locus_tag="ABM27_RS03945"
     CDS             6849..7151
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676628.1"
                     /locus_tag="BN2145_RS04030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03945"
                     /product="DUF4235 domain-containing protein"
                     /protein_id="WP_047121486.1"
                     /transl_table=11
                     /translation="MGKSKKKKLPLAYQPVGFVLGWAGGALAGMAFRKTWKVLRHEDDA
                     PDALDPDRGWGEILLAAAVQGAIFAVVRSAVDRTGAKAIARSTGVWPSKDSGGRD"
     gene            complement(7248..7640)
                     /locus_tag="BN2145_RS04035"
                     /old_locus_tag="ABM27_RS03950"
     CDS             complement(7248..7640)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978082.1"
                     /locus_tag="BN2145_RS04035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03950"
                     /product="VOC family protein"
                     /protein_id="WP_047121487.1"
                     /transl_table=11
                     /translation="MALVNAGVVVLDCAEPEKLAEFYKALLGGEETEATANRVEIRGAD
                     GFRMAFRRDVNATPPSWPRPENSLQAHLDFVVEDLDAAERGVVGLGGRPLEAKDAPGPY
                     EERSFADPAGHSFTLRRVASTAPKQG"
     misc_feature    7635..7645
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    complement(7774..7788)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 24.69"
                     /tool="antismash"
     misc_feature    7775..7789
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.29"
                     /tool="antismash"
     gene            complement(7833..9395)
                     /locus_tag="BN2145_RS04040"
                     /old_locus_tag="ABM27_RS03955"
     CDS             complement(7833..9395)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852331.1"
                     /locus_tag="BN2145_RS04040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03955"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_029384837.1"
                     /transl_table=11
                     /translation="MLRRRWTGPLLLATLLTVLAPLPAQAAEPPPAAAPAAAAGATTPR
                     TAAATAAVPLPSLSATTTQVASGLRRPTALVAPDDGTGRLFITEKSGTVRVYHPDTGLA
                     RTPLIDITSAVDESGNERGLLGIAVPPDFATSQDLYLAYTALPDGAVTLARYRLDASRL
                     EVLLSQEHAEYNNHNGGQLAFGPDGKLYWSIGDGGGSGDPFRAGQRLDTLLGKIVRIDV
                     ARSCGTLPYCVPGDNPFVGTANARPEIWLYGLRNPWRFSFDRADGSLWIGDVGQGHWEE
                     VDHLAPGQGGANLGWSCYEGLEKFEGGHCPPGEEYTKPVFTYSPYTGGCSVIGGHVYRG
                     KKYADLVGGTYIATDYCSSTVWALRPDGRGGYDQAEIGKMPTQVTSIGTTVDGEFYVVN
                     DLPGGLHRVSFTREEPTCRVDRTVRSWGTGLTVDLTVTNTGDTPVNGWALQFPLAFGQK
                     VVSDWNTDLTQLSNVITATDAGHNATIPPGGSVTLGYLAEHTGDASAPPRFTLNEDACA
                     VGR"
     misc_feature    complement(9390..9392)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..11029
                     /locus_tag="BN2145_RS04045"
                     /old_locus_tag="ABM27_RS03960"
     CDS             10001..11029
                     /EC_number="4.2.3.169"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040594.1"
                     /locus_tag="BN2145_RS04045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03960"
                     /product="7-epi-alpha-eudesmol synthase"
                     /protein_id="WP_029384838.1"
                     /sec_met_domain="T1TS (E-value: 1.7e-70, bitscore: 237.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQDVRFDLPFDTPVSEHLAYARERHLRWVRERGLVRSQAGFEEYV
                     SWDLAQAAARTYPYASPDGMVVLMNWFSLAFLFDDQFDAGRPDRADRIAEVARELIVTP
                     LRPAGAAPRVVCPITLAWAEVWEQLSHGMSLTWKTRFAASWGRFLAAHCEEVDLAARGL
                     AGSLGVAEYTAFRRRTVGIHHSIDAGEASRGFEVPAQAMAHPLMERMRDLAADTIGFMN
                     DIHSFERERRRGDGHNLVAVLHRERGCSWAEAADAAYRMTTTCLGEYLELEARVPQMCD
                     ELGLDAEQRLRVEMGVEAIRHWINGNYEWALTTGRYAAVKEGPVATAESAGRGSVDDLL
                     TV"
     gene            complement(11173..12414)
                     /locus_tag="BN2145_RS04050"
                     /old_locus_tag="ABM27_RS03965"
     CDS             complement(11173..12414)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994860.1"
                     /locus_tag="BN2145_RS04050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03965"
                     /product="cytochrome P450"
                     /protein_id="WP_029384839.1"
                     /sec_met_domain="p450 (E-value: 3.2e-07, bitscore: 28.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDQTTPGAAGGCPVAHGGAPRLYGPEAATDPQGLYSRLRKQYGV
                     VAPVLLEGDVPAWLVLGYRENRRVLDNPLQFSRDSRIWRDWREGRVDESSPLIPMVGWR
                     PDCVSQDGEPHQRLRAAVTDNLNAVAGRGIRRHATHYAHKQIDAFAGAGRADLVSDFAE
                     YLPMLVLTRVFGLAEAEGRRLAESSNLVIKGGADALAHNERIMGILGELTARKRAEPGS
                     DFTTGLIEHHAGLDEEEIVNHLRLVLITAHTMTSNLLARALQLVLTDTSWLSGLVSGQL
                     DISTVVEEVMWNRPPLAVLPGRFATADLELGGCPIKKGDLLVLGLAAGNSDPDIRPDAD
                     VSVQGNQSHLAFSAGPHECPGQNIGQAIIETAVDVLLHRLPGLRLAVPPEELTSTASTW
                     EDRLDSLPVEFTAA"
     gene            complement(12411..13016)
                     /locus_tag="BN2145_RS04055"
                     /old_locus_tag="ABM27_RS03970"
     CDS             complement(12411..13016)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156547.1"
                     /locus_tag="BN2145_RS04055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03970"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_029384840.1"
                     /transl_table=11
                     /translation="MDLNGFDRPGRPTAGDTRSVKVMIAGGFGTGKTTMVRSVSDIKPL
                     TTEETLTQASADVDRLIGVADKTQTTVSLDFGKISLNDTLMLYLFGTPGQERFWFLWNG
                     LFKGALGAVVLVDTRRLASSFRAIEEMERQNVPFVIALNVFPDSRDFPVEEIRDALDIA
                     PHIPVVSFDARDRASSRDVLVTLIRHLKDRPAVALEPR"
     gene            complement(12997..13368)
                     /locus_tag="BN2145_RS04060"
                     /old_locus_tag="ABM27_RS03975"
     CDS             complement(12997..13368)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995719.1"
                     /locus_tag="BN2145_RS04060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03975"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_029384841.1"
                     /transl_table=11
                     /translation="MSAPRRPTDPSGLERYYVLTGGRSGPGGSASSLDVATLVVARAVP
                     LPGMQYEHAEILRRCRDPLSVAELGAHLHLPFNILAVLLSDLLDAGRIEARDPIPAHDA
                     GRGPDLALLEEVLSGLERL"
     misc_feature    complement(13231..13233)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13365..13775)
                     /locus_tag="BN2145_RS04065"
                     /old_locus_tag="ABM27_RS03980"
     CDS             complement(13365..13775)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057749.1"
                     /locus_tag="BN2145_RS04065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03980"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_029384842.1"
                     /transl_table=11
                     /translation="MTYQGTDVSWALRDLVESIQEIRFALVASSDGKAITSYGAEDPDD
                     VDRFAAVVAGLQALAQPVAEQFPGHAGQLRLAMIEVDGGHLFVVRAGVETYLGVLAREG
                     LDQGLLGHQMRDLARRMGELLGTTPRLEEHSG"
     gene            complement(13780..15492)
                     /locus_tag="BN2145_RS04070"
                     /old_locus_tag="ABM27_RS03985"
     CDS             complement(13780..15492)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327712.1"
                     /locus_tag="BN2145_RS04070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03985"
                     /product="ATP-binding protein"
                     /protein_id="WP_047121488.1"
                     /transl_table=11
                     /translation="MELATPPPAARAPVAWYSWWLMPLGLGGGTVAATFMSSERITAAV
                     AGVTATAASAVCVRLLVRTQARLRRTERDFRASQEETTRQWQRHVAGLEREFATERAAR
                     ETRLAELEQTHRAQLAEQAQTYEAQLTERDRSLEERLSEQAASYEARLAEQSETARERL
                     AHQLAAVARLADEQLPSALDRLRAGDAIDDILPSVEQCAKVGAELQAELRKVLRTALMG
                     VEREFDRSTSAEQAVISIGNRIHVLTSKLRGRLHEMQGEHGRLPAVARGLMELDQAIGP
                     ADCLAASISVLGGSDRPGRQWQEPQRLLSVVRGGIGRIKDFHRVQVRHLPELGVDGGLV
                     DHLTLIFAHLLDNAARYSPPTEPVLVSGKEVPNGVGIEIQDSGKGLSEEKKREAEHALA
                     GTALGAGLGGITEDANIGLRVVGILARRYGIRVTFTDSPWLGTSVVVVVPHKYFSPLPS
                     AVPAPAAVTAQGAPAVPPHEPPAAPAGAVETTPGGLPRRRSRRGDGDRPRQAGRTERTA
                     RGSFSAVPPDASFAGLAAFATAGRDAGETSGPAGDRDTTTGGASTEHRTEESD"
     gene            16083..17033
                     /locus_tag="BN2145_RS04075"
                     /old_locus_tag="ABM27_RS03990"
     CDS             16083..17033
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (25-313). E-value: 5.3e-56.
                     Score: 181.9. Matches aSDomain:
                     nrpspksdomains_BN2145_RS04075_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979474.1"
                     /locus_tag="BN2145_RS04075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS03990"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_029384845.1"
                     /sec_met_domain="ADH_N (E-value: 8.3e-10, bitscore: 37.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.4e-15, bitscore:
                     55.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDVNTMRAISQDTLGGPEVLREVRLERPVPRPNEVLVRVRAAGV
                     NPTDWKHRANGGFLGEPPFVLGWDVAGTVEAVGIGVAAVQPGDEVFGMLPYPFGHGSHA
                     EYVIAPARALVPKPAGIDHVQAGALPLVSLTAWQALVERADVRPGQRVLIHAAAGGVGH
                     VAVQIAKARGAYVIGTASAGKHDFLRSIGVDEPVDYRRADFAEAVRDVDAVLDTIGGDT
                     ALRSLRVLRPGGIVVSILPVGPEEFLREAERLGVRAVRMLVDADQGGMRAIAGLVESGK
                     LRATIAQTFPLSEAARAHEQGETGRTTGKLVLVTD"
     aSDomain        16158..17021
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN2145_RS04075_PKS_ER.1"
                     /evalue="5.30E-56"
                     /label="BN2145_RS04075_PKS_ER.1"
                     /locus_tag="BN2145_RS04075"
                     /protein_end="313"
                     /protein_start="25"
                     /score="181.9"
                     /tool="antismash"
                     /translation="LERPVPRPNEVLVRVRAAGVNPTDWKHRANGGFLGEPPFVLGWDV
                     AGTVEAVGIGVAAVQPGDEVFGMLPYPFGHGSHAEYVIAPARALVPKPAGIDHVQAGAL
                     PLVSLTAWQALVERADVRPGQRVLIHAAAGGVGHVAVQIAKARGAYVIGTASAGKHDFL
                     RSIGVDEPVDYRRADFAEAVRDVDAVLDTIGGDTALRSLRVLRPGGIVVSILPVGPEEF
                     LREAERLGVRAVRMLVDADQGGMRAIAGLVESGKLRATIAQTFPLSEAARAHEQGETGR
                     TTGKLVL"
     CDS_motif       16527..16589
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN2145_RS04075_0001"
                     /evalue="1.70E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="BN2145_RS04075"
                     /protein_end="169"
                     /protein_start="148"
                     /score="26.8"
                     /tool="antismash"
                     /translation="GQRVLIHAAAGGVGHVAVQIA"
     misc_feature    complement(17105..17119)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.62"
                     /tool="antismash"
     misc_feature    17106..17119
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.14"
                     /tool="antismash"
     gene            17232..17612
                     /locus_tag="BN2145_RS04080"
                     /old_locus_tag="ABM27_RS03995"
     CDS             17232..17612
                     /GO_function="GO:0045152 - antisigma factor binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040626.1"
                     /locus_tag="BN2145_RS04080"
                     /note="This anti-anti-sigma factor, or anti-sigma factor
                     antagonist, belongs to a family that includes characterized
                     members SpoIIAA, RsbV, RsfA, and RsfB; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ABM27_RS03995"
                     /product="anti-sigma factor antagonist"
                     /protein_id="WP_029384847.1"
                     /transl_table=11
                     /translation="MRHQPAPLTRHLRVRRERAYTVLEFHGEIDIAAAAEIAPHLERET
                     DRPEALIVLDLGRIEFFDCSGLRLLCRARQRVLDRGGRLHLVCTHPLTLRVLRITGLTR
                     LLPPHPTVGAALEQTEAACGPG"
     gene            complement(17616..18569)
                     /locus_tag="BN2145_RS04085"
                     /old_locus_tag="ABM27_RS04000"
     CDS             complement(17616..18569)
                     /EC_number="2.7.6.1"
                     /GO_component="GO:0002189 - ribose phosphate
                     diphosphokinase complex [Evidence IEA]"
                     /GO_function="GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995732.1"
                     /locus_tag="BN2145_RS04085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS04000"
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="WP_029384848.1"
                     /transl_table=11
                     /translation="MRDIAVFSGSAHPELAEEVCAHLGVPLSPVRVSRFANDCLEVQLR
                     ANCRERDVFLVQPLIRPVQEHLVELLLMCDAARGASAGRITVVMPHYSYARSDKKDAPR
                     ISLGGRLVADLLVTAGASRVLTMTLHAPQVHGFFSVPVDHLHALRELAAHFRRYDLTRT
                     TVVSPDLGNAKEAAAFARLIGARVAAGAKQRYADDRVTITSVIGDVAGRDVIVLDDEIA
                     KGSTVLELLDRLREAGPRSIRVACTHGLFAAGALKRLGEQPDVLEIVCTNTVPVPAGHH
                     TDKLRVLSVAPAFAEAVRRIHNGESVSALFDAPPTV"
     misc_feature    18806..18815
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            18902..19564
                     /locus_tag="BN2145_RS04090"
                     /old_locus_tag="ABM27_RS04005"
     CDS             18902..19564
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823408.1"
                     /locus_tag="BN2145_RS04090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS04005"
                     /product="DUF4230 domain-containing protein"
                     /protein_id="WP_029384850.1"
                     /transl_table=11
                     /translation="MTTPTSRLPGRVPGWVKALAALAVVLAVLFAGLRLSVIPGLKDVF
                     GTETHDRSGPALLKSIRDISRFEAASGTFQVVVDLEKDTRLLPDAIRGTRTLYVGAGTV
                     DAYVDLGKVGEDDVTVNGDRTSATLRLPRAALGTPALDPERSYAVSKQRGLLDRLGDLF
                     SDNPNGEQAVQKLAVRHIAEAAEDSGLTARAESNTTGMLQGLLRSLGFKEVRVSYGE"
     gene            19670..20209
                     /locus_tag="BN2145_RS04095"
                     /old_locus_tag="ABM27_RS04010"
     CDS             19670..20209
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823409.1"
                     /locus_tag="BN2145_RS04095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS04010"
                     /product="VanZ family protein"
                     /protein_id="WP_029384851.1"
                     /transl_table=11
                     /translation="MARAVPRPRFLARPRAPEAEEPARPERRPLPLPLRLLAMACAFVF
                     MVAFAVVLARLTLHPSPASESLTHTNLHPGRSLEAYLDQPALRDAVKQIGGNVLLGVPF
                     GVLVPVVAPRTRRMLRVLALTALVMLLVEFAQGALVTGRAFDIDDVILNTTGALVGYLL
                     LGRRLSRAVHARRPAH"
     gene            complement(20331..20567)
                     /locus_tag="BN2145_RS04100"
                     /old_locus_tag="ABM27_RS04015"
     CDS             complement(20331..20567)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117104.1"
                     /locus_tag="BN2145_RS04100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABM27_RS04015"
                     /product="hypothetical protein"
                     /protein_id="WP_029384852.1"
                     /transl_table=11
                     /translation="MTEIASLHITHPRITVLGVQPARPPFRIVEIDGQVVGEARNLIDV
                     LEAAAAFGITVHDLDDPEAVRWVGGDKFTWTRH"
     misc_feature    20608..20623
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.31"
                     /tool="antismash"
ORIGIN
        1 ggcagggccg tacgcggtga gtctcctgga gggcagaagc gatggcgaac acgtccccgt
       61 ccgtgcgccg gacggccctg ctggcgagtg cggtggcggc gctgggcgcg ctgaccgcct
      121 gcggcacgga cggcgccgcg accggcgcca cgacgagcgc cgtgacgggc ggcacggccg
      181 ggaccgcccg gcagtcgcct gccacgggaa cgccgccggg caccgccgtc agttcgcccg
      241 ccggttccgt ggagcggtcg ccctctcgtg ccgtgccgag cgacacggcg ggatccgcgt
      301 ccgcctccgc ccggtccgac ggccgctgtc acacctccga gctgcgcgcg tcggtcggcc
      361 gggtcgaccc gggcgccgga cagcggaact tccccgtcgt actgaccaac atctcgtcgc
      421 gcacctgcac cctgtacggc tatccgggcg ccgccttcac cgactcctcc ggccgccagg
      481 tgggcccgga tccgcggcgt gcgcccggct cccctgagac ggtgacgctg gcgcccggcc
      541 ggagcgcctg ggccgggctg tcgttcgcga gcccggacgt cagcggcgcc cgcgccgcga
      601 ccccggcggt gctgctggtc accccgccgg acgagcggga ctccctgagg gtggagtgga
      661 agggcggcaa ggtgcccgtg ggcggcaccg cgtccacggt gtccgtcacc gtgctggaca
      721 ccggcaccgg gccctgagac acggcgtgct tcgcggcggg caccggccgc ccgtgggacg
      781 gtggccggtg cccgccgcgg cgtccggtca gtgaccggcg accgggtgcg gcgtgtaggg
      841 ccgctccagt tcctcgatct cctcgtcggt cagctccagt tcgaccgcgg ccaccgcgtc
      901 gtccaggtgc tgcggcttgg acgcgccgat gatcggcgcg gtcaccgtgt cctggtgcag
      961 cagccaggcg agggccaccc gggcgcgcgg gacgccccgg tcggcggcga tacgggtgac
     1021 ggcctcgacg atggcgcgat cgccctcctg gtagagggtg ctgccgaagg tgtcggtggc
     1081 actgcgcccg gtggtggtgc cccagtcccg ggtgagccgg ccgcgcgcga gcgggctcca
     1141 cggcagcacc ccgacgccct ggtccgcgca gagcggcagc atctcgcgct cttcctcccg
     1201 ataaaggagg ttgtagtggt tctgcatgga gacgaacgtg gtccagccgt tgagccgcgc
     1261 ggtgtactgg gccttggaga actgccaggc gtacatcgaa ctggccccga tgtagcgcac
     1321 cttgccggac ttcaccagat cgtggagcgc ctccatggtc tcctcgatcg gcgtgtgcgc
     1381 gtcccagcgg tggatctggt acaggtcgac gtagtcggtg cccaggcgcc gcaggctgtg
     1441 gtcgatctcg gtcatgatcg ccttgcggga cagtccggcg ccgttgggcc cggggcgcat
     1501 ccggtagtgg accttcgtgg cgagcacgat ctcgtcccgg cgggcgaagt cgcgcagcgc
     1561 ccgtccgacg atctcctcgc tggtgccgtc ggagtagatg ttggcggtgt cgaagaaggt
     1621 gacgcccgcc tccagcgcct gccggatcag cgggcgcgcg gcctcctcgt cgagggtcca
     1681 ctcgtgcacg ccgcggtcgg ggaccccgta ggtcatgcac cccagacaga tccgcgacac
     1741 gtccaggccg gtcgaaccga gcttcacata ctgcatcctt gccgctgctc cttcgcgttc
     1801 ggtaccggga acgagcctac gtgttcgcgt gcactccagg tccgggccgc tcagccgtcg
     1861 agcaggtcca gcgcccgttc ccagccgaac tcccgtcgtc cggcgccttt tccgggttcg
     1921 ccggtgtacg ggtcgccgaa gcggacgccc atggcgcgca gccgggccac gctctcctgg
     1981 taggcggggt gcgcggccag cgcgtcggcc acgcacggca ggacggcgag gggtacgccg
     2041 agcccgtacg cctcgcacag ggtgcccacg gcgagggtgt cggcgatgcc ggcggcccat
     2101 ttgttgaggg tgttgaaggt ggccggcgcg acgatcacgg cgtccggcgg cgggaagggg
     2161 cgcgggtcgc ccgggcggcg cgccccggcg cggaccgggc ggccggtcga ctcctcgacg
     2221 gcggcggtgt cgaagaatcc gtccgccgcg gcggtcgggg tggcgatcac cccgacctcc
     2281 caaccgcgcc ggtgcgccgc ggcgatgagc gtcccgacgt ccgcggcgac cccggccgcg
     2341 cagacgacga cgtagaggaa gggcttggcg tcctgttcga tcacccgggc accctactga
     2401 agggggaacg ggcgcccgcg ctcggtctcg ggccggggcc cgcggatccg gcgctccccc
     2461 tcctcgatcg ggacgtcgtc gatgctcgcc tcgcggcggg ccatcaggcc gtgctcgtcg
     2521 aactcccaca gttcgttgcc gtaggagcgc caccaccggc cctccgcgtc gcgcgactcg
     2581 tactggaagc gcaccgcgat gcggttgccc tcccaggccc acagttcctt gcgcagggcg
     2641 tagtcccgct cgcgctgcca cttgcgggtc aggaactcga cgatggcggc gcgcccggtc
     2701 aggaaggtgt cccggttgcg ccagacggag tcccgcgtgt acgcgagcgc cacccggtgc
     2761 gggtcgcggg tgttccaggc gtcctcggcg gcctgcacct tcagggcggc ggtctcccgg
     2821 gtgaacggcg ggagcggcgg acgggcggtc atgggtcctc cccggcggca gaatgagaac
     2881 gggcgttctc cacaaggctg ttaccgtatg agaacgatcg ttctcaggtc aaggaggggt
     2941 ccccgcatgg acatcgaggt cgcccgggag cgggcgctgg acgccgccga gacactgttc
     3001 tacggccggg gtgtgcagtg cgtcggcatg gacgacatcc gcgccgcctc cggcctctcg
     3061 ctcaggcgtc tgtaccagct cttcccggcc aaggagcagt tggtggcggc ctatctggag
     3121 cggcgcgatg tgcgctggcg ggggcggctg gcgcagtaca ccgggcggta cgcggagccg
     3181 cggcggcgga tcctggccgt cttcgactgg ctggagcggt ggttcggcga accggacttc
     3241 cgcggatgcg cgtggatcaa cgcccacggt gagctcggcg ccctctcgcc cctggtggcg
     3301 gagcgggttc gggcgcacaa gcgggccttc gggcggttcc tcgacgagct ggtcgccgga
     3361 gcgggcctgc cggccccgct gggcggacag ttgttcctgc tggcggaggg cgccatggtg
     3421 acggcgggca tcacggggag cgcggaaccc gcggcccgcg cgcgcgaggc ggcgcgggcc
     3481 ctgctggcgg cccgctgacc ggcgtcggac ggcggccggc gacgccaccg cctcccgtgc
     3541 cgcggccggc gacgccgcgg cccgtcccac cgccccggcc ggcccgggca gcaggtcgaa
     3601 tccctgcggg gacacgctcc cggagcgggt ggcgggcggc gcgccggagg acgaggcggt
     3661 gctggccgag tcggtgggcc tcgccctgct ggtggtgctg aacgagctcg gcccggccga
     3721 gcgggtggcg ttcgtgccgc acgacctgtt cggtgtgccg ttcgaccgga tcgcggcggt
     3781 caccgggcgg tcccggccgg ccgccaagaa gctcgccacc cgcgcccgag ccaaggtgcg
     3841 gggcgtcccg gtgctgccgg gtgccgagct ggagcggcac cggcaggtcg tcgaggcgtt
     3901 cccgggcgcc gcccggggcg gtgacctggc cgcgctgctc gacgtcctgg caccggacgt
     3961 cgtccggcgg gccgatccgg tggccgtacc gcccggtggc ccggtcgaac tgccgggtgc
     4021 ccgggcggtg gtggaaggga cgctgctgct gcggcagcgg gcccggtcca ccgcgctcgc
     4081 cctggtggac ggcaccgtcg gcgcggtggt cgcgccgcgc gggcggctgg tgtgcgccct
     4141 gcggatcacc gtcgccgacg gtcgggtcgc ctcgtacgag gtggtggcgg agccggagcg
     4201 gtgccgcccg ctcggcctcg cggtgctgga tctcccgccg cgaacggcgc ccgggcacgc
     4261 cctcgcggct gcgcacgacg ggaactgacg ggccgtcgga cagcgatcgg gcgcgcggag
     4321 agccgggcgg tgaagaaacg ggcgccctcg tggccgcccc gcccgacgcc cgctgccggg
     4381 cggggccggg aaaggccgac ggacgggagg ggagaccggg gagttctttc ccggccgggc
     4441 gcgcatgaag cggggatggc cgggcatccg ggtgtcaggc cccgccgcgc tcccccgtcg
     4501 cggcggggct ttcccgtgcc tcctgcgccg ggcggtcggt cacgtcgagg aagatctgcc
     4561 gcgcttcggg cacggtgtgg gctatggacc gcttgatgcg gacggcgacc tcctcgaccc
     4621 gctcgctgtc caggccgggc accaggtcga cgcgggccgc caccagggcg gagtccaggc
     4681 ccgtcttcat cgtgaacagc gcttccacgc tgtcgatctc cggctgcgcc tggagcagcg
     4741 cccggatccg gccactggcc tccgggtcgg cggcctcccc gatcaactgg tcgcgggcct
     4801 cgcggcccag gcggtaggcg acgtacacca gcagggtgcc gatcgcgagg gaggcgcacg
     4861 cctcccacac cacctggccg gtggccatgt ggagcaccat gccggcgatc gccagcgtca
     4921 ccccgaccac ggcggtgccg tcctcggcga cgaccgtacg cagcgccggg tcgcgcaggc
     4981 cgcgcgagcc gccctggtgg cgcacctggt acagggcccg cagcagcgac gcgccctcgg
     5041 ccagcagggc gacgccgagc acgaccaggc cggcgacata gccgccgagc tcctccgcgg
     5101 ccccgccgcg gagggcttcg acgccctggt agaaggagaa gcagccgccc atcacgaaga
     5161 tcccgacggc cgcgagaagg gaccagaaga accgttcctt gccgtaaccg aaagggtgcc
     5221 gccggtcggc ggggcggcgg ctgcggcgca gcgcggccag caggaagacc tcgttcatgc
     5281 tgtcggccac cgagtgcgcc gcctccgaca gcagggcggg cgatccggcg aggaagccgc
     5341 cggccgcctt ggcgaccgcg atcaccagat tggccgccag cgccaccagc acggtgacgc
     5401 gggtcctgcg gtcggccttc gtgccggtgc ccccgtccgg gccgccctcg gcgttcccct
     5461 ccgtcgtctc tccccctgcg tcgccgcccc ctttcccctc ctggtgcgcc gccgcggacc
     5521 ggtgtggtgt gccgtccgcc gcccggtgcg cctcgcgctg ctccgtcttc cgctccgtct
     5581 gccgatccga ggatgtcccg ctcacgtctc gccgactgcc ccggccgggc gcgcctcaca
     5641 cccttcttgt gggtggctca ccagtgccga cggcgcaaaa cggggaacgc gtccaccagg
     5701 gcacccgcac gacgggtacg actgggaggt gaggtgcatg agcggcgacg gcgggggcgg
     5761 cggcaaccgc gcgtacggca ggaagacgtt caagcggtcc aggagccact tcgcggaccg
     5821 gatcaccgcg gacgggcggg acggctggcc ggtggagccc ggccggtacc gcctggtggt
     5881 cagccgcgcc tgtccctggg ccggccgggc ggtgatctcc cggcggctgc tcggtctgga
     5941 ggacgccctg tccctggcga tcgccgaccc ggtccaggac gaccgtagct ggcggttcac
     6001 cctcgatgcg gacggtcgcg acccggtgct cggcatccgg tacctcggcg aggcgtacga
     6061 caagcgggag acggggtatc cgggcggggt gagcgtaccg gcgatcgtgg acgtgcccag
     6121 tgggcggctg gtcaccaacg actaccagca gatcaccctg gatctggcca cccagtggtc
     6181 ggcgctgcac cgtccgggag cgcccgacct gtacccgccg gcgctgcggg acgagatcga
     6241 ctcggtgatg gcggaggtct acgaagacgt caacaacggt gtctaccggg cgggcttcgc
     6301 caccggccag cgtgagtacg aggccgcctg cacggccgtg ttcgagcggc tggagctgct
     6361 cgcgcggcgg ctggagaggc ggcgctatct ggtcggcgac acgatcacgg aggcggacat
     6421 ccggctgttc accacgctgg tccgcttcga cgccgtctac cacggccact tcaagtgcaa
     6481 ccgctggaag ctgacggaga accgggtcct gtgggcgtac gcccgcgatc tgttccagac
     6541 gcccggcttc ggcgacaccg tcgacttcga tcacatcaag cgccactact accaggtcca
     6601 caccggcatc aatcccaccg ggatcgttcc gctgggcccg gacctgtccg ggtggctgac
     6661 cccgcatcac cgtgaggagc tgggcggccg gcccttcggc gacgggacgc cgccgggtcc
     6721 ggtccccgcc ggggagcggg tccccgcacg gggccgcccc tgacagtcct cctcccccgc
     6781 gcgcggccgg catcggtcgg cgcgcccgcc gaacacccac cgcacacgca tcacacaagg
     6841 agatccacgt gggcaagagc aagaagaaga aactccccct cgcctaccag cccgtcgggt
     6901 tcgtgctggg ctgggcgggc ggcgcgctgg ccggcatggc cttccgcaag acctggaagg
     6961 tgctccggca cgaggacgac gcgcccgacg cgctcgaccc ggaccgcggc tggggcgaga
     7021 tcctgctggc ggccgcggtg cagggtgcca tcttcgccgt ggtgcgcagc gccgtggacc
     7081 ggaccggggc caaggccatc gcccgctcga ccggggtctg gccctccaag gacagcggcg
     7141 gccgggactg atgacgcgag ccccggtgcc ggccggacgc catccacggg gtccggccgg
     7201 caccggggct ctcgctcgcc cgccccgccg gggcgggcgg acggggctca gccctgcttg
     7261 ggcgccgtcg acgcgacacg gcgcagtgtg aaggagtggc ccgccgggtc ggcgaagctc
     7321 cgctcctcgt agggaccggg cgcgtccttc gcctccagcg ggcgtccgcc gagcccgacg
     7381 accccgcgct cggccgcgtc cagatcctcc accacgaagt ccaggtgggc ctggagggag
     7441 ttctcgggcc ggggccagct cggcggggtg gcgttcacat cacgccggaa ggccatgcgg
     7501 aaaccgtccg ctcccctgat ctccacccgg ttggcggtcg cctccgtctc ctccccgccc
     7561 agcagcgcct tgtagaactc ggcgagcttc tcgggctcgg cacagtcgag caccacgacg
     7621 cccgcgttca ccagtgccat gtctcctccg aagggatccc aggcgcgaaa cggccgtgcc
     7681 ccgcgccctg ttaccttgcg gatatcccgg cccggcggat tcagtcggtc gcgggcctcc
     7741 ggcctggccg tcggcacacg gggcgagccc gggtggggag cgctcccacg accaggaagc
     7801 gctccccctc ggccggcccg cgggccggcg gctcagcgtc cgacggcgca ggcgtcttcg
     7861 ttgagggtga accgcggcgg cgccgaggcg tcgccggtgt gttcggcgag gtagccgagg
     7921 gtgacgctcc cgcccggcgg gatcgtcgcg ttgtgcccgg cgtcggtcgc cgtgatcacg
     7981 ttgctcagct gggtgaggtc ggtgttccag tcggagacga ccttctgccc gaacgccagc
     8041 gggaactgga gcgcccagcc gttcaccggc gtgtcaccgg tgttggtgac ggtgaggtcg
     8101 accgtcaagc cggtgcccca ggaccgcacg gtgcggtcga cccggcaggt gggctcctcc
     8161 cgggtgaacg acacccggtg caggccgccg ggaaggtcgt tgaccacgta gaactcaccg
     8221 tcgaccgtcg tgccgatcga cgtcacctgg gtgggcatct tcccgatctc ggcctggtcg
     8281 tacccgcccc ggccgtccgg ccgcagtgcc cagacggtgg acgagcagta gtcggtggcg
     8341 atgtacgtgc cgcccaccag atcggcgtac ttcttccccc ggtagacgtg gccgccgatg
     8401 accgagcagc cgccggtgta cggggagtag gtgaagacgg gcttggtgta ctcctcaccg
     8461 ggcgggcagt ggccgccctc gaacttctcc agaccctcgt agcaggacca gccgaggttc
     8521 gccccgccct gtccgggcgc gagatggtcg acctcctccc agtggccctg gccgacgtcg
     8581 ccgatccaca gcgagccgtc ggcgcggtcg aaggagaacc gccacgggtt gcgcagcccg
     8641 tacagccaga tctccgggcg ggcgttcgcg gtgccgacga aggggttgtc cccggggacg
     8701 cagtacggga gcgtgccgca gctccgggcg acgtcgatcc gcacgatctt gcccagcagg
     8761 gtgtccaggc gctgcccggc gcggaaggga tctcccgagc cgccgccgtc gccgatgctc
     8821 cagtacagct tgccgtcggg gccgaaggcg agctggccgc cgttgtggtt gttgtactcg
     8881 gcgtgttcct gggagagcag gacctccagg cgggatgcgt cgagccggta gcgggcgagg
     8941 gtgaccgcgc cgtcggggag cgcggtgtac gccaggtaca ggtcctggct cgtggcgaag
     9001 tcgggcggga cggcgatgcc gagcaggccg cgttcgttgc ccgattcgtc caccgccgag
     9061 gtgatgtcga tcagcggggt gcgggcgagg ccggtgtccg ggtggtagac gcggacggtg
     9121 ccggacttct cggtgatgaa caggcggccc gtgccgtcgt cgggggcgac cagggcggtg
     9181 ggccgtcgca ggccggaggc gacctgggtg gtcgtggcgc tgagcgacgg cagcggcacc
     9241 gcggcggtgg ccgccgcggt ccggggcgtg gtggccccgg cggcggccgc gggtgccgcg
     9301 gcggggggcg gttcggcggc ctgggcgggc agcggggcca ggacggtgag gagggtggcg
     9361 agcaggaggg gaccggtcca gcggcgtcgt aacatgtcgg ctccaggagc gaggacgctt
     9421 gcacggcggt ggcgcttcca tgggcagcag gcacgaccgc gccgccgccc gccgggctgg
     9481 ccggacacgg acggccgcgc gcggggacac ggatgccgga accggccggg tggggaaccg
     9541 gccgggccga aggatcgtgt gcgtccccca ggtgtgcctg ccgggacggt aaccgctctc
     9601 ccctgcgtca caccaggccc ttaccgcgac ttccggccgg gcggacactc ggacaccacg
     9661 cacgcggcag gcggacaccg gggccaccgt ccgcccgccg ggtctctcgc tcgcggggcg
     9721 ggccgggcgt acgcgcaccg cctccacggc ccggccggta agtcgagcgg cgtcgccgca
     9781 ggtgggaagc gggcgagtct acgcggccgc cgacgcgcgg gcagtaacca agatcacgag
     9841 atgaccaccg tgtagatcat ttacggcctg ggcagcctcg taccgctttt cggttcgatc
     9901 ttcgagccgc gaaggcgagt tcgacagcgc gggtggtcgg ggagaccgcc cgctcgcagg
     9961 ggcggggggg ctctgcggtc cgtctcccga aaggaagccc atgcaggacg tccggttcga
    10021 ccttcccttc gacacccccg tcagtgagca cctggcctac gcgcgggagc gtcatctgcg
    10081 ctgggtgcgg gagcgagggc tggtgcgcag tcaggccggg ttcgaggagt acgtgtcctg
    10141 ggatctggcc caggccgccg cccgcaccta cccgtacgcc tcgccggacg gcatggtggt
    10201 gctgatgaac tggttctccc tggccttcct cttcgacgac cagttcgacg cgggccggcc
    10261 cgaccgggcg gaccggatag ccgaggtggc ccgggagctc atcgtcacgc cgctgcggcc
    10321 cgccggggct gcgccgcggg tggtctgccc catcacgctg gcctgggcgg aggtctggga
    10381 acagctctcg catggcatgt ccctgacctg gaagacgcgt ttcgccgcct cctgggggcg
    10441 gttcctggcg gcgcactgcg aggaggtgga cctggcggca cgggggctgg ccgggtcgct
    10501 gggggtggcg gagtacaccg cgttccggcg ccgcacggtc ggcatccacc acagcatcga
    10561 cgcgggcgag gccagccgcg gtttcgaggt gccggctcag gcgatggcgc atccgctgat
    10621 ggagcggatg cgggacctgg ccgcggacac catcgggttc atgaacgaca tccactcctt
    10681 cgagcgggag cggcgccgcg gggacggcca caacctcgtc gccgtcctgc accgggagcg
    10741 ggggtgctcg tgggcggagg ccgccgacgc ggcctaccgc atgacgacca cctgcctcgg
    10801 cgagtacctc gaactggagg cccgcgtccc gcagatgtgc gacgagctgg ggctcgacgc
    10861 ggagcagcgg ctccgggtgg agatgggcgt ggaggccatc cggcactgga tcaacggcaa
    10921 ctacgagtgg gcgctgacca ccggtcgcta tgcggcggtg aaggagggcc cggtggccac
    10981 ggccgagtcg gcggggcggg gttcggtgga cgacctgctg acggtctgac ccctgttgcc
    11041 cctgcgggtg ccgcccggcc gggtcgccgg acgggcggtg gccgggcggt ggcccggttg
    11101 cggggggcag gcaccggacc gggcggttcc ggccgcctcg ccgccggacc gcctcgccgg
    11161 cccacccggg cctcaggccg cggtgaactc caccggcagg ctgtccaggc ggtcctccca
    11221 ggtggaggcc gtggaggtga gttcctccgg gggcacggcc aggcgcaggc ccggcaggcg
    11281 gtgcagcagg acgtcgacgg cggtctcgat gatggcctgg ccgatgttct gcccgggaca
    11341 ctcgtgcggt ccggcgctga aggccagatg ggactggttg ccctggacgg agacgtcggc
    11401 gtccgggcgg atgtccgggt cggagttccc ggccgccagg cccagcacca gcaggtcccc
    11461 cttcttgatc gggcagccgc ccagttccag gtcggcggtg gcgaaccgtc ccggcagcac
    11521 cgccagcggg ggcctgttcc acatcacctc ctccacgacc gtggagatgt cgagctgtcc
    11581 gctcaccagc ccggacagcc aggaggtgtc ggtgaggacg agctggagcg cccgggcgag
    11641 caggttgctg gtcatggtgt gggcggtgat gagcaccaga cgcagatggt tgacgatctc
    11701 ttcctcgtcg agcccggcgt ggtgttcgat gagcccggtg gtgaagtcgg agcccggctc
    11761 cgcgcgcttg cgggcggtca gctcgccgag gatgcccatg atgcgttcgt tgtgcgccaa
    11821 cgcgtccgcg ccgcccttga tgaccaggtt gctggactcg gccaggcggc gcccctccgc
    11881 ttcggccagc ccgaagaccc gcgtgagcac cagcatgggc aggtactcgg cgaagtcgct
    11941 caccagatcg gcgcggccgg cgccggcgaa ggcgtcgatc tgcttgtgcg cgtagtgcgt
    12001 ggcgtggcgg cggatgcccc ggccggcgac ggcgttcagg ttgtcggtga ccgcggcgcg
    12061 cagccgctgg tgcggttccc cgtcctgcga gacgcagtcg gggcgccagc ccaccatcgg
    12121 tatcaggggc gagctctcgt cgacccggcc ctcgcgccag tcccgccaga tccgtgagtc
    12181 gcggctgaac tggagcgggt tgtcgagtac ccggcggttc tcgcggtagc ccagcaccag
    12241 ccaggcgggg acgtcgccct ccagcaggac gggggcgacg actccgtact gcttgcgcag
    12301 ccgggagtag aggccctgcg ggtccgtcgc cgcctcggga ccgtacaggc gcggggcgcc
    12361 gccatgggcg accgggcagc cgccggcggc gccgggagtg gtctggtcgt tcatcggggc
    12421 tccagggcga cggccgggcg gtccttcagg tgacgtatga gggtgacgag cacgtcacgg
    12481 ctggaggccc ggtcgcgtgc gtcgaaggac acgaccggga tgtggggggc gatgtcgagc
    12541 gcgtcgcgga tctcctcgac cgggaagtcc cgggagtcgg ggaagacgtt cagcgcgatg
    12601 acgaagggca cgttctgccg ctccatctcc tcgatcgccc ggaaactgga cgccagccgc
    12661 cgggtgtcga ccagcacgac cgcgccgagc gcgcccttga acagcccgtt ccacaggaac
    12721 cagaagcgct cctggccggg ggtgccgaac aggtacagca tcagcgtgtc gttgaggctg
    12781 atcttcccga agtccaggct gacggtggtc tgtgtcttgt cggcgacgcc gatgaggcgg
    12841 tcgacgtcgg cgctggcctg ggtgagggtc tcctcggtgg tgagcggttt gatgtcgctg
    12901 accgagcgga ccatggtggt cttcccggtg ccgaagccgc cggcgatcat caccttgacc
    12961 gagcgggtgt caccggccgt gggccggccg ggccggtcaa agccgttcaa gtccactgag
    13021 tacctcctca aggagcgcga ggtcgggccc gcggccggcg tcgtgtgccg ggatggggtc
    13081 gcgggcctcg atgcggcccg cgtccagcag gtccgacagc agcaccgcga gaatgttgaa
    13141 gggcagatgg aggtgggcgc cgagttcggc caccgacagc ggatcgcggc agcgccggag
    13201 gatctccgcg tgttcgtact gcatgcccgg taaggggacg gcgcgggcga ccacgagagt
    13261 cgccacgtcg aggctcgacg ccgaaccgcc cggtccgctg cgcccgcctg tgaggacgta
    13321 gtagcgctcg agaccggacg ggtccgtcgg ccggcgggga gcactcatcc agagtgctcc
    13381 tccaggcgcg gcgtggtgcc gagcagctcg cccatcctgc gggccaggtc cctcatctgg
    13441 tgtcccagca ggccctggtc gagaccctcg cgggcgagaa cgccgagata cgtctcgacg
    13501 cccgcgcgga cgacgaagag gtggcctccg tcgacctcga tcatggccag ccgcaactgc
    13561 ccggcgtggc cggggaactg ctcggcgacc ggctgggcca gcgcctgcag cccggccacc
    13621 acggccgcga agcggtcgac gtcgtcgggg tcctcggcgc cgtaggacgt gatggccttg
    13681 ccgtcgctgg aggcgacgag ggcgaagcgg atttcctgga tgctctccac aagatcgcgg
    13741 agcgcccagc ttacgtcggt tccctggtac gtcatggcac tagtcgctct cttctgtgcg
    13801 gtgctcggtg gacgcgccac cggtggtcgt gtcgcggtcg ccggccggtc cggaggtctc
    13861 gccggcgtcc cggccggcgg tggcgaacgc ggccagaccg gcgaaggagg cgtccggcgg
    13921 gacggcggag aagctgcccc gtgcggtccg ctcggtacgt ccggcctgcc gggggcggtc
    13981 gccgtcgccg cgccggcttc tgcgccgggg cagcccgccg ggggtggtct ccacggcacc
    14041 ggccggcgcg gccggcggct cgtgcggggg gaccgccggg gcaccctgcg ccgtgacggc
    14101 ggcgggggcc ggcacggccg acggcagcgg gctgaagtac ttgtgcggta cgacgaccac
    14161 gaccgaggtg ccgagccacg gggagtcggt gaaggtgacg cggatgccgt agcggcgggc
    14221 gaggatgccg acgacccgca ggccgatgtt ggcgtcctcg gtgataccgc cgaggccggc
    14281 gccgagcgcg gtgcccgcga gggcgtgctc ggcctcgcgt ttcttctcct cgctcaggcc
    14341 cttgccggag tcctggatct cgatgccgac gccgttgggg acctccttgc cggagaccag
    14401 caccggttcg gtgggcggcg agtagcgggc cgcgttgtcg agcagatggg cgaagatcag
    14461 cgtcaggtgg tccaccaggc cgccgtcgac gccgagttcg ggcaggtggc gcacctggac
    14521 gcggtggaag tccttgatcc ggccgatgcc gccgcgcacc acgctcagca ggcgctgcgg
    14581 ctcctgccac tgccggcccg ggcggtcgga accgccgagc acgctgatgc tggccgccag
    14641 gcagtcggcg gggccgatcg cctggtcgag ttccatcagg ccccgggcga ccgcgggcag
    14701 ccgtccgtgc tcgccctgca tctcgtgcag tcgtccgcgc agcttgctgg tcaggacgtg
    14761 gatgcggttg ccgatgctga tgacggcctg ttccgcggag gtcgaccggt cgaactcgcg
    14821 ctcgacgccc atgagggcgg tgcgcagtac cttgcgcagc tcggcctgca actcggcgcc
    14881 gaccttggcg cactgctcga cgctgggcag gatgtcgtcg atggcgtcac cggcgcgcag
    14941 ccggtccagc gcgctcggca gttgctcgtc ggcgagccgg gccacggcgg ccagctggtg
    15001 cgccagccgc tcccgcgcgg tctcggactg ctcggcgagc cgggcctcgt aggacgcggc
    15061 ctgctcgctc agccgttcct cgagggaccg gtcccgctcg gtgagctgcg cctcgtaggt
    15121 ctgggcctgt tcggccagtt gcgcccggtg cgtctgttcc agctcggcca gtcgcgtctc
    15181 ccgggcggcg cgctcggtgg cgaactcgcg ctccagaccc gccacatgcc gctgccactg
    15241 ccgcgtggtc tcctcctgcg aggcgcggaa gtcacgctcc gtgcgccgca gccgggcctg
    15301 cgtgcggacc aggaggcgca cgcacacggc gctggccgcc gtcgccgtga caccggcgac
    15361 ggccgcggtt attcgctccg agctcatgaa cgtggcggct accgtcccgc ctcccaggcc
    15421 cagcggcatc agccaccagc tgtaccaggc gacaggggcc cgcgccgcag gtggcggagt
    15481 ggcgagttcc atctgcatcc ttcgaagcaa cacgatcgat caggggggtg cgcaaggggg
    15541 accgcactca tgggtacgca gggcgatccg agccgtcgcg atcgcgtcaa ctcgcagcgc
    15601 cgatcggaac cttatcgggt tcgaacggaa aaggatcaat ctcaacgacc tgcggaagtg
    15661 agggttccgt cactctccgc caggaaacgc ggggcgggcg aatcaccccg cgggccagcg
    15721 cagttgccct ccccgccggg gcgggcggcc ccttcccgcg gtgccggatg agccgggggc
    15781 ctgtggccgg gggcctcgtc gtgacagcgg cgggcgacgg cgcgcgcacg aggggagccg
    15841 gggcgccgga cagcggcgta cgggccgcgg gcgggggccg gccctgtggc cgtcgtccgg
    15901 aaccgggcgg cgcggggcac gagagcgcga tcggcgcccg gcggcgggtc cggcggggga
    15961 cgccgtcggg gcgagcgacg ccgcgccttc cccgggcccc ggacctccgc acggcgtgat
    16021 cgtcgccagg tcggaccgct caccgtgttc cggacgggcg gagtcgggca ggctgggaca
    16081 ccatgagcga tgtgaacacc atgcgagcca tcagccagga caccctcggc gggcccgagg
    16141 tcctgcggga ggtacggctg gagcgccccg tgccgcgccc gaacgaggtg ctggtccggg
    16201 tgcgcgccgc cggcgtcaac ccgaccgact ggaagcaccg cgccaacggc ggcttcctgg
    16261 gcgagccgcc cttcgtgctc ggctgggacg tggccggcac ggtcgaggcg gtcgggatcg
    16321 gggtggcggc ggtccagccg ggcgacgagg tcttcggcat gctgccctac ccgttcggcc
    16381 acggctccca cgccgagtac gtcatcgccc cggcccgcgc gctcgtgccg aaaccggccg
    16441 ggatcgacca tgtgcaggcg ggcgcgctgc cgctggtgtc gctgaccgcg tggcaggccc
    16501 tggtggagcg ggcggacgtc cgtccgggac agcgggtgct gatccacgcg gcggccggcg
    16561 gcgtcggcca tgtggccgtg cagatcgcca aggcgcgcgg cgcgtacgtg atcggcaccg
    16621 ccagtgcggg caagcacgac ttcctgcgct ccatcggggt ggacgagccg gtcgactacc
    16681 gccgggccga cttcgcggag gccgtgcggg acgtcgacgc cgtcctggac acgatcggcg
    16741 gggacaccgc cctgcgctcg ctgcgcgtgc tgcgcccggg cggcatcgtg gtgtcgatcc
    16801 tgccggtcgg gccggaggag tttctccggg aggccgagcg gctcggtgtc cgggcggtcc
    16861 ggatgctcgt cgacgccgac cagggcggca tgcgggcgat cgccggcctg gtggagtccg
    16921 ggaagctgcg cgccaccatc gcgcagacct tcccgctgtc cgaggccgcc cgggcgcacg
    16981 agcagggcga gaccggccgt acgacgggca agctggtcct cgtgaccgac tgacatcggc
    17041 catccgcaca cacgccgacg gccgcgccgc tcctcgcacc gcaggtcaca cgagctgtct
    17101 cgagaatttg aagacatatg tcaatcgaac atgctcaaat tcgttcgatc gagggtaact
    17161 tgcggggcga ggacaggcgg tgctgtccca cgatcccacc gtccagggag cagtctggag
    17221 gcgatgccgt cgtgcggcac caacccgcac cgctcacccg gcatctgcgc gtgcgccgcg
    17281 agcgggcgta cacggtgctg gagttccacg gcgagatcga catcgccgcg gcggccgaga
    17341 tcgccccgca tctggagcgg gagacggacc ggccggaagc cctgatcgtg ctcgacctcg
    17401 gccggatcga gttcttcgac tgctccggcc tgcgactgct gtgccgggcc cggcagcggg
    17461 tgctggaccg cggcggacgg ctccatctgg tctgcaccca tccgctgacg ctgcgcgtcc
    17521 tgcggatcac cgggctgacg cggctgctgc caccgcatcc gacggtcggg gcggccctcg
    17581 aacagacaga ggccgcctgc gggccgggat gaacctcaga cggtgggcgg cgcgtcgaac
    17641 agggcgctga cggactcgcc gttgtggatc cgccgtacgg cttccgcgaa cgcgggggcg
    17701 accgacagga cgcgcagctt gtccgtgtgg tggccggccg ggaccgggac ggtgttggtg
    17761 cacacgatct ccagcacgtc cggctgctcg ccgagccgct tgagcgcgcc cgccgcgaac
    17821 agcccgtgcg tgcaggcgac gcggatggaa cgcgggcccg cctcccgcag ccggtccagg
    17881 agctccagga cggtactccc cttggcgatc tcgtcgtcga gcacgatgac gtcccgtccg
    17941 gcgacgtcac cgatcacgga ggtgatggtc acccggtcgt cggcgtagcg ctgcttggcg
    18001 cccgcggcca cccgggcacc gatcagccgg gcgaacgcgg cggcctcctt ggcgttgccg
    18061 aggtccggcg agacgacggt ggtgcgggtc aggtcgtagc gccggaagtg ggcggccagc
    18121 tcccgcaggg cgtgcaggtg gtccacgggc accgagaaga agccgtgcac ctgcggcgcg
    18181 tgcagcgtca tggtgaggac ccggctcgca cccgccgtca ccagcaggtc cgccaccagg
    18241 cgcccgccca gcgagatgcg gggagcgtcc ttcttgtccg agcgggcgta ggagtagtgc
    18301 ggcatgacga cggtgatgcg gcccgccgag gccccgcgcg ccgcgtcgca catcagcagc
    18361 agctcgacga ggtgctcctg caccggccgg atcagcggct ggaccaggaa gacgtcccgc
    18421 tcccggcagt tggcccggag ctgcacctcc aggcagtcgt tggcgaaccg gctgacccgg
    18481 acggggctga gggggacgcc gaggtgcgcg cagacctcct cggccagctc cgggtgggcg
    18541 ctaccgctga acacggcgat gtctcgcacg gaccgctcct cgcgtgatcg tgtcgggccg
    18601 gggcctcagg ccaccgacga ggacatcccg tcgcggcgca cccgcgcagg cacgccatga
    18661 cggcgcggtc cgttgtctgc ccgccccggg cgccctccat gcgcccccac cgcggaatca
    18721 cccggctccc gcaccgtcgc gggcccgttc gggacggcca ccggcgcgtc accggacgcc
    18781 gggggagtcc gaggcgtccg cacgggaagg cggccgggct cgtacgcccg cacgcctcaa
    18841 ctcccctgtc tggcgggcgg catgagcggg catccggaca tcaggaagga gggccgccgc
    18901 catgacgact cccaccagcc gcctgcccgg gcgagtgccc ggctgggtga aggcactggc
    18961 cgcgctcgcg gtggtgctcg ccgtgctctt cgcgggcctg cggctgagcg tgatcccggg
    19021 cctgaaggac gtgttcggca ccgagacgca cgaccgctcg ggccccgcgc tgctgaagtc
    19081 catccgggac atcagccgtt tcgaggccgc ctccggtacc ttccaggtgg tcgtggacct
    19141 ggagaaggac acccggctcc tgccggacgc gatccggggc acccgcaccc tgtacgtggg
    19201 tgcgggcacc gtcgacgcct atgtcgacct cggcaaggtc ggcgaggacg acgtgacggt
    19261 gaacggggac cgcacgtcgg cgacgctgcg gctgccgcgc gccgcgctcg gcacaccggc
    19321 cctggacccc gagcgctcct acgccgtctc caagcagcgc ggcctcctgg accgcctcgg
    19381 cgacctcttc tcggacaacc cgaacggcga acaggccgtg cagaagctcg ccgtgcggca
    19441 catcgcggaa gccgccgagg acagcgggct gaccgcgcgc gccgagagca acaccaccgg
    19501 catgctccag ggcctgctgc ggtccctggg gttcaaggag gtgcgggtgt cgtacgggga
    19561 gtgagcgggc cgggcggggc ggcatcggcg gcgccccggc gggtaaccgg tccctcactc
    19621 agcggtcaac tcctctcacg caggaaagcc gacgtctgga ggacacctca tggcccgtgc
    19681 agtcccacgg ccgcgttttc tagcccgccc gcgcgccccc gaggcggagg aacccgcccg
    19741 gcccgagcgg cgcccgctgc ccctacccct gcgcctgctc gcgatggcgt gcgcgttcgt
    19801 gttcatggtg gcgttcgcgg tggtcctggc ccggctcacc ctgcacccct cccccgcctc
    19861 ggagtcgctg acgcacacca acctgcaccc cggccgctcc ctggaggcgt acctggacca
    19921 gccggcgctg cgcgacgccg tcaagcagat cggcggcaac gtgctgctcg gcgtgccctt
    19981 cggtgtgctg gtcccggtcg tcgccccgcg gacccgccgg atgctgcgcg tcctggcgct
    20041 gaccgccctg gtgatgctgc tggtggagtt cgcgcaagga gcgctggtca ccggccgcgc
    20101 cttcgacatc gacgacgtca tcctcaacac taccggggcg ctggtcggtt acctgctgct
    20161 ggggcggcgc ctgagccgcg cggtacacgc gcgccggccc gcgcactgag ggccgcgtcc
    20221 gccgccccgc cgggtccggg ggcccgcctg gcacggaggc acggcccggg gagtgtccgg
    20281 caccgcccgt cgtccgcccg ccgggcgggc ggggagccgc cggacactcc ctagtgccgg
    20341 gtccaggtga acttgtcgcc gcccacccag cggaccgcct cgggatcgtc caggtcgtga
    20401 accgtgatgc cgaacgcggc ggcggcctcc agcacgtcga tgaggttccg cgcctcaccg
    20461 accacctgac cgtcgatctc cacgatccgg aacggaggcc gcgccggctg cacgccgagc
    20521 accgtgatcc gcggatgggt gatgtgcagg ctcgcgattt cggtcataca gagagcgtag
    20581 agcgcaatca gccattatgg ccttttcgcg ccgttcgcga acacatcaca ggtgtgttct
    20641 cagcgcctac gagtgtgttc tccgggagta caggggcgca ttcccagggg gtggccgacg
    20701 ggcggacgcg ggtgaggccg taccggtcgc ggggaccggt acgcggtcgc ggggcggccc
    20761 gttcaggggc gccgccagtc gtcgccggtc agatgcgatc cggccatcgg ccccatccgc
    20821 agcatgccgc cgtccacgct ccaggaggcg ccggtgacgt acgaggcgtc gggcccggcg
    20881 aggaacgcga tcaccgcggc gacctcgcgg gcgtcgccgg gccgtccgag cggcacgccg
    20941 ggccggtgcc gggtgtgcgg gtcgacgtcc tcctggccgg tcatgggggt ggcgatctcg
    21001 ccgggcgcga ccgcgttgac ggtgatgcc
//
