LOCUS       NZ_LDCN01000003        24525 bp    DNA     linear   CON 11-DEC-2024
DEFINITION  Brevibacillus formosus strain DSM 9885 Scaffold3, whole genome
            shotgun sequence.
ACCESSION   NZ_LDCN01000003
VERSION     NZ_LDCN01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Brevibacillus formosus
  ORGANISM  Brevibacillus formosus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Brevibacillus.
REFERENCE   1  (bases 1 to 907092)
  AUTHORS   Wang,J.P., Liu,B., Liu,G.H., Chen,Q.Q., Zhu,Y.J., Chen,Z. and
            Che,J.M.
  TITLE     Genome Sequence of Brevibacillus formosus F12T for a
            Genome-Sequencing Project for Genomic Taxonomy and Phylogenomics of
            Bacillus-Like Bacteria
  JOURNAL   Genome Announc 3 (4), e00753-15 (2015)
   PUBMED   26205874
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 907092)
  AUTHORS   Liu,B., Wang,J., Zhu,Y., Liu,G., Chen,Q., Chen,Z., Lan,J., Che,J.,
            Ge,C., Shi,H., Pan,Z. and Liu,X.
  TITLE     Genome sequencing project for genomic taxonomy and phylogenomics of
            Bacillus-like bacteria
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 907092)
  AUTHORS   Liu,B., Wang,J., Zhu,Y., Liu,G., Chen,Q., Chen,Z., Lan,J., Che,J.,
            Ge,C., Shi,H., Pan,Z. and Liu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) Agricultural Biological Resources Research
            Institute, Fujian Academy of Agricultural Sciences, 247 Wusi Road,
            Fuzhou, Fujian 350003, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. May-2015
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001012775.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:34:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,848
            CDSs (total)                      :: 5,688
            Genes (coding)                    :: 5,626
            CDSs (with protein)               :: 5,626
            Genes (RNA)                       :: 160
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 3, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 146
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 27 of 62
            Pseudo Genes (incomplete)         :: 43 of 62
            Pseudo Genes (internal stop)      :: 9 of 62
            Pseudo Genes (multiple problems)  :: 14 of 62
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:55:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 799260
            Orig. end                         :: 823785
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LDCN01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24525
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24525
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24525
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14525](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14525
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(39..52)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.3"
                     /tool="antismash"
     gene            381..929
                     /db_xref="GeneID:87585956"
                     /locus_tag="AA984_RS12825"
                     /old_locus_tag="AA984_12840"
     CDS             381..929
                     /codon_start=1
                     /db_xref="GeneID:87585956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015894007.1"
                     /locus_tag="AA984_RS12825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12840"
                     /product="hypothetical protein"
                     /protein_id="WP_047070229.1"
                     /transl_table=11
                     /translation="MNSLTHLTNSIPWQRLTTAYGRGTDIPQLIETRQYEELANLIEHQ
                     STLWQTTPWVLLILLQELTKQKPEQVSSQEIQLYLAVASAINVDEMDSQNAVETMNELL
                     DEKYLWPEDEEDDELWWEEEEPRGYEQEAFFSYYSFSYLLLKDAIPVFTAIMRGNDKLA
                     PAIQELLLMLQSKDVRTVE"
     gene            complement(968..1414)
                     /db_xref="GeneID:87585957"
                     /locus_tag="AA984_RS12830"
                     /old_locus_tag="AA984_12845"
     CDS             complement(968..1414)
                     /codon_start=1
                     /db_xref="GeneID:87585957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007720260.1"
                     /locus_tag="AA984_RS12830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12845"
                     /product="DUF4375 domain-containing protein"
                     /protein_id="WP_047070230.1"
                     /transl_table=11
                     /translation="MSKVDIHDVWFDFAAAFVQKKNALGWNTLTSQEQEIAALWLLEAD
                     VYNGGFLQFFCNWGEEAYIYAVRALQAIGAVHALEIVQSGYACIEHLSEDDRLTQLWDI
                     PRFLTEEEEERLDKLDQSFWEDQDRIAEVAHRYYVQQLEVPAPS"
     gene            1569..2948
                     /db_xref="GeneID:87585958"
                     /locus_tag="AA984_RS12835"
                     /old_locus_tag="AA984_12850"
     CDS             1569..2948
                     /codon_start=1
                     /db_xref="GeneID:87585958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016739444.1"
                     /locus_tag="AA984_RS12835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12850"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_047070231.1"
                     /transl_table=11
                     /translation="MDQVLIEQLNCWHEEDEHQKIVDLLIAVPEEKREYEAVSRLGRAY
                     NNLGLYEEALNQLKKITEAGQQDPVWHFRVGYALYHLKRYEEAGQSFRTSDKLETGNQN
                     TESWLRWSLQKAEKQQRQELRMAAKRAAAVEGSASEEVPFSNMSLEDFWDDSEYAKKAY
                     QSAPPTDELIASIEEELGYKLPASYLALMKQQNGGIPKNTCFPTEDPTSWAEDHIAITG
                     ILGIGREKSYSLCGDLGSRFMIEEWGYPDIGVVICDCPSAGHDLVMLDYRECGRDGEPE
                     VIHVDQENDYEITFLAENFEAFIRGLVSEEEYDTSEEDKEAALYKVAHGKFSSLLEELC
                     TPVSEVEQIDQKIRGICTRIVEEKGYFSFHADEFSYLMYDVQFWLYTKSYPDTTREQYL
                     AVYEKMIAFGGEFGQGGYAPGWISEWLDRRKEEGRIVQENGHIRFTDQFAAEVIQQLRE
                     A"
     gene            complement(3038..4759)
                     /db_xref="GeneID:87585959"
                     /gene="cysI"
                     /locus_tag="AA984_RS12840"
                     /old_locus_tag="AA984_12855"
     CDS             complement(3038..4759)
                     /EC_number="1.8.1.2"
                     /GO_component="GO:0009337 - sulfite reductase complex
                     (NADPH) [Evidence IEA]"
                     /GO_function="GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /GO_process="GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585959"
                     /gene="cysI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007720258.1"
                     /locus_tag="AA984_RS12840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12855"
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="WP_047070232.1"
                     /transl_table=11
                     /translation="MSENHLLSPNSAPHSDVEDIKRRSDYLRGSLAETLEDRISGSIPE
                     DDNRLMKFHGSYMQDDRDLRNERSKQKLEPAYQFMVRVRAAGGVVTPEQWLMMDDIAQK
                     FANGTIRLTTRQSFQLHGVIKWNMKQVIQEVNEALLSTLAACGDVNRNVMCNPNPYESE
                     VHQEVYEWAKKISNHLDPRTRAYHEIWLDEEKVVDSRDGVEQEPIYGPVYLPRKFKIGI
                     AVPPANDVDVFSQDLGFIAIHEEGRLLGFNVAVGGGMGMTHGDPKTYPQVARVIGFATP
                     EQVLDVAEKTVMIQRDYGDRAVRKHARFKYTIDDRGIEWFVHELEQRLGWELEQARPYH
                     FEHNGDRYGWVKGSDDNWHFTLFIQNGRVKDEDNYLLKSGLREIAKVHTGDFRLTPNQN
                     LLIGNVTSEKKPEIEQIIQAYGLTDGAAYSALRRNSMACVSLPTCGLAMAEAERYLPTL
                     LDEIELILDEAGLRDEEIVIRMTGCPNGCARPALAEISFIGKAVGKYNMYLGGGFSGNR
                     LNKLYRENIGEKEILNELRPILNRYAKEREEGEHFGDFVIRAGYVKEVKSGLDFHE"
     gene            complement(4794..6620)
                     /db_xref="GeneID:87585960"
                     /locus_tag="AA984_RS12845"
                     /old_locus_tag="AA984_12860"
     CDS             complement(4794..6620)
                     /EC_number="1.8.1.2"
                     /GO_component="GO:0009337 - sulfite reductase complex
                     (NADPH) [Evidence IEA]"
                     /GO_function="GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585960"
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007720257.1"
                     /locus_tag="AA984_RS12845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12860"
                     /product="assimilatory sulfite reductase (NADPH)
                     flavoprotein subunit"
                     /protein_id="WP_047070233.1"
                     /transl_table=11
                     /translation="MVLKVTDSPFSQEQVELLNRLLPTLSEVQKVWLSGYLAALHKVEA
                     PMAAGFQATLAANGPVISKEVTVLFGSQSGNSQKLAKVLTGKLQEHGFHVTLSSMSDFK
                     TNALKKVENLLVVVSTHGDGEPPDNALSFHEFLHSKRAPQLEGLRFSVLALGDTSYELF
                     CQTGKEFDKRLEELGGKRLTPRVDCDVDYDEQASEWMNQVLASLSETTATQVAAASAFV
                     GGAVIGSGSLTEYSRSNPFQAVVLENLNLNGRGSDKETRHLEISLEGCNLEYEPGDCLG
                     IYPKNHPGLVRELIDAMGWKPEEPVPINKNGEELPLEEALSSHFEITLLTKPLLEQAVK
                     LSSGNGLQELLAEGREQELRDYVRNRDLLDLVEDYDLKGVPAKDFVSVLRKLPPRLYSI
                     SSSLKSYPDEVHLTIRNVHYQAHGRDRYGVCSSYIADRLETGDTLPVFVQHNPNFKLPA
                     NPDIPLIMIGPGTGVAPFRAFLGEREELGATGKTWLFFGDQHFSTDFLYQLEWQRWLKQ
                     GVLTHMDVAFSRDTSEKVYVQHRMLEKSKELYQWLQAGAHVYVCGDEKKMAHDVHAALV
                     TVLQKEGGLDSEEAVAYLKRMQQEKRYQRDVY"
     gene            6920..7873
                     /db_xref="GeneID:87585961"
                     /locus_tag="AA984_RS12850"
                     /old_locus_tag="AA984_12865"
     CDS             6920..7873
                     /codon_start=1
                     /db_xref="GeneID:87585961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007720253.1"
                     /locus_tag="AA984_RS12850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12865"
                     /product="YndJ family transporter"
                     /protein_id="WP_047070234.1"
                     /transl_table=11
                     /translation="MKPLMVATIPGGIITILIFFLDYFRLQLVDKFLMFAAFVIVPLVI
                     LLLRYDEKNKHQRVIYAALKLLQYPAALLALASVMGSKTWGLGSTAIPGTLSLGWLLFT
                     FLLGIYGLTVIVNRKGRTEEIAIGTGLVYFFIGGIWFTLYQYQFDLFQAKPTTHALSSV
                     HFHFSSAIVPIFIGLLGRVMTKKSWYPWVVAVDIIGPILIAVGIIFSKPIEYIGVTLFA
                     CNIAIYTTYLLGYLRNGSVQNKSSFFLVLSCMAFYTIVVVSICYPLLKNMFSLTIHDFI
                     PIYGALHSFGFVLCGLIGWVYIIDSLKEKYNKEQQE"
     gene            complement(8367..9035)
                     /db_xref="GeneID:87585962"
                     /locus_tag="AA984_RS12855"
                     /old_locus_tag="AA984_12870"
     CDS             complement(8367..9035)
                     /codon_start=1
                     /db_xref="GeneID:87585962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017246793.1"
                     /locus_tag="AA984_RS12855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12870"
                     /product="YdeI/OmpD-associated family protein"
                     /protein_id="WP_047070235.1"
                     /transl_table=11
                     /translation="MSKTIVEKLNLQKYQKTAVLHTPEGEESLAVLKEADHELKDVQYD
                     MIFAFVLDMKSLQELMMKVIDHSYLLEGGLLYVAYPKKGNKVYPTYIHRDELFDGLGAD
                     EDGYIGTSTIKFNRMVGMNEVFTVVGFKNEKKKAAKASSKPSQCVDDYIDFVPKIEEDL
                     RNAPKELTFYQSLTPGYQKDWARYVYSAVQEGTRTKRRAEMITVLAEGFKSIDLYRRGK
                     "
     misc_feature    9378..9394
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.5"
                     /tool="antismash"
     misc_feature    complement(9379..9394)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 24.29"
                     /tool="antismash"
     misc_feature    9433..9448
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.49"
                     /tool="antismash"
     misc_feature    complement(9463..9479)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.09"
                     /tool="antismash"
     misc_feature    9470..9483
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     misc_feature    9471..9484
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     gene            9687..9854
                     /db_xref="GeneID:97007566"
                     /locus_tag="AA984_RS31200"
     CDS             9687..9854
                     /codon_start=1
                     /db_xref="GeneID:97007566"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038155.1"
                     /locus_tag="AA984_RS31200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FDLD family class I lanthipeptide"
                     /protein_id="WP_371863599.1"
                     /transl_table=11
                     /translation="MFDLDVQVNAVGTNGAEPNTIRTALCWVTRVTCKSTCTCVCTAMC
                     TPGCPFSDEK"
     CDS_motif       9687..9743
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MFDLDVQVNAVGTNGAEPN"
                     /locus_tag="AA984_RS31200_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9744..9854
                     /prepeptide="core"
                     /locus_tag="AA984_RS31200_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="12.50"
                     /molecular_weight="3737.4"
                     /monoisotopic_mass="3734.7"
                     /core_sequence="TIRTALCWVTRVTCKSTCTCVCTAMCTPGCPFSDEK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFDLDVQVNAVGTNGAEPN"
                     /leader_location="[9686:9743](+)"
                     /alternative_weights="3755.5"
                     /alternative_weights="3773.5"
                     /alternative_weights="3791.5"
     gene            10001..13222
                     /db_xref="GeneID:87585963"
                     /locus_tag="AA984_RS12860"
                     /old_locus_tag="AA984_12875"
     CDS             10001..13222
                     /codon_start=1
                     /db_xref="GeneID:87585963"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="AA984_RS12860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12875"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_047070236.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.2e-188,
                     bitscore: 623.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.9e-14,
                     bitscore: 49.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.6e-36, bitscore:
                     121.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERQSKVKKHAKKESRSFFRTMDFFMLRTPLLPIHMFLELCQADW
                     KLENLDPRKQSIIRECLAVASPSLLESLNKLEQSDREQLEQVARSLLRYGIRMSTRSTP
                     FGLFSGIACGHFDTNTNLLVNKMEQHKKRSRPDMEWLLKIVQSLEENLDVVKQLYVQTN
                     TMYEVVGNRVSLPYITRYGQNQNGYQIENVSIAMNELIALVLQKATEPILFMELFQIIK
                     QSYPDTEDNRIESFLFQLVKNEFLFTSLRPRLTHSSPFDHLLAVLERVEGIDERYQQLL
                     SIRQEINAYDQLKIGQGETHFLSTLSKMKSVESSSSQLQVDLSLSTEQVTLPKSIAKDL
                     SKAAELLWRLSPNHIGWPHLAEYRDSFIERYGFEREVPLLDLLDENRGLGAPATYENPM
                     SKRNYTPSSHDKINEKVLLQLLSHSLLTGSKEIELTDDLIEKLEPVSPKWEQVPLSMEL
                     YISLFAPSAKAMDNGDYTIHIGGNTGSMLAGKSFGRFADMLGESFEEKLEQINQEHQKA
                     YPDSIFAEVVYFPRHGRIANVVLSKSKRKYEILIGVPSSEHHSLNIPLSDLVVGATSDS
                     FYLKSRSMNKEVIPVTGHMLNYVGSVPNVYRFLCELGIAKQRNWMPFSWGSFRHAPVLP
                     RLRYGKIVLAPATWNVDPELLSVSKKDGKENWMEAVQIWKRQYQVPDYVYITDHDNKML
                     LDLKSERHLAELIRELQKLKSGEALILTEVGAELKDCVVEGEDGVFHMECVFPLVKNTP
                     VEASATESVSVTTGVHPRRALISDQERLKMPGSDWLFYKLYCDEARMDEFIAFPLQSLC
                     ETMHVKGACQKVFFMRYTDPKPHIRLRFQAASTEGLQSIFSEMYQWTYEMQKQGYLSKT
                     TIDTYDPEIERYGGPQLIPLAEELFFMDSMVVAQWLQLHRTKQMNIPLEKVAVISIIDL
                     LHQFLHSIDEKLSFLNKIISYKAYLDDFRTDREFYLKAGRYTNDWQELKLLEGGSVLHQ
                     LFQVRSEAINNFSTVMHSLKAQSELYNSQEQIIGSIIHLHVNRLLGIDREQERKVMTLA
                     RHTLHNLRYFLLQEESQTKETAHAF"
     aSDomain        10475..10756
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AA984_RS12860_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.00E-15"
                     /identifier="RREFam001.1"
                     /label="AA984_RS12860"
                     /locus_tag="AA984_RS12860"
                     /protein_end="252"
                     /protein_start="158"
                     /score="49.2"
                     /tool="antismash"
                     /translation="YVQTNTMYEVVGNRVSLPYITRYGQNQNGYQIENVSIAMNELIAL
                     VLQKATEPILFMELFQIIKQSYPDTEDNRIESFLFQLVKNEFLFTSLRP"
     gene            13212..14525
                     /db_xref="GeneID:87585964"
                     /locus_tag="AA984_RS12865"
                     /old_locus_tag="AA984_12880"
     CDS             13212..14525
                     /codon_start=1
                     /db_xref="GeneID:87585964"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="AA984_RS12865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12880"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_052773399.1"
                     /sec_met_domain="LANC_like (E-value: 2.9e-69, bitscore:
                     229.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSNTKSWQPIHNATLIKNIEHVVKQVARKLQYPHEVLGEPLPGT
                     DSLASGAMGIVLFYAELDRLYPDEQWDVVAHNYLVHVQTVINADMFNSFSLWSGLSAAP
                     VVASILARDRGRYQNFIEKLHILIQPAIDGFIDQARGRIGNDLFIPDYDVIEGLAGIGR
                     YLLFFKEHPACKENLNKVLSYIIQLTKNIHFNGESVPGWHIRSENQFLEFEKKRYPNGN
                     FNFGISHGIAGPFALLSLALLEGIEVEGQRDAISKLCSYYEKWKTEDEHGPIWPERISF
                     EEETCGQMQNPFTYNASWCYGEPSIARVLWLAGQALGDTELQSLAQQTYLSLVQRSVES
                     LGFESPTFCHGYAGTLWMLQRMMMDTSSDAFEAYREKLVNQILSTFNDNHAYGFQDIEH
                     GQFRDLPGLLVGAAGVALVLLSCLSLDEPEWDCIFLLK"
     gene            14662..16386
                     /db_xref="GeneID:87585965"
                     /locus_tag="AA984_RS12870"
                     /old_locus_tag="AA984_12885"
     CDS             14662..16386
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585965"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016739435.1"
                     /locus_tag="AA984_RS12870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12885"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_236697867.1"
                     /transl_table=11
                     /translation="MILNILQGLFPVGMLYVTQELVNAVSSGISQDGDTVVISFLFFIS
                     FILVKQLVTLIQNYVEGLFQSLLSNRLREMVLDKANAMGLADFENAEVQDQLKRAQQET
                     SYRPYQIFELVLSIVSGVISLVSTSLFLIFWKWWVVFILVLFPLISFYSYLRLSQQEFY
                     IRWSRAERERRGWYISHLLTHDRAFKEVQIYKLGSYLITQFRDMITQFFYEDKKIATIR
                     LKTSLVFESLTIAMIGFMSFIAIKAAFLKEILLGNLVSYIQGITLTQTTSQSLMHSLIG
                     LSQHNMFVEQLFLFLERNSSDPVKLQKVAITTPQENDPFVLESIEFVNVSFTYPETARP
                     VLQNLSFKIRKGESLAIVGENGSGKTTLVKLLTLLYKDYEGQILINGTDLNAFDMEQIR
                     AKIGVVFQDFMQYEMSIRNNVGFGDLSLLHQDDKLYHALEKSGMRSLAEGFEQGLDTQL
                     GKWFTEGLQLSGGQWQRIAIARAFLRNADLYILDEPSASLDPMAEKEVFDSFNLLTKER
                     MGIFISHRYSSAQYADQIMVLDQGRIVEFGTHTELIRLQQKYASLYNLQASPFVSQS"
     gene            16418..16558
                     /db_xref="GeneID:87589146"
                     /locus_tag="AA984_RS30135"
     CDS             16418..16558
                     /codon_start=1
                     /db_xref="GeneID:87589146"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA984_RS30135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_160309982.1"
                     /transl_table=11
                     /translation="MTFLTALMSSLAHIGAIHIALIILIVIGIWKWISNKKKKNDNSGE
                     S"
     gene            complement(16954..17190)
                     /db_xref="GeneID:87792286"
                     /locus_tag="AA984_RS31130"
     CDS             complement(16954..17190)
                     /codon_start=1
                     /db_xref="GeneID:87792286"
                     /inference="COORDINATES: protein motif:HMM:NF036760.5"
                     /locus_tag="AA984_RS31130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_330218231.1"
                     /transl_table=11
                     /translation="MIEQHEDTNIWCSEIVDFVTEWRCFIRYGEILDVRQYKGAWDSKL
                     DLRVIKSAVKDFIDAPAAYGLDFGIDRDGNMKL"
     gene            complement(17204..17482)
                     /db_xref="GeneID:87792287"
                     /locus_tag="AA984_RS31135"
     CDS             complement(17204..17482)
                     /codon_start=1
                     /db_xref="GeneID:87792287"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AA984_RS31135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_327957345.1"
                     /transl_table=11
                     /translation="MRAYIQANKSGEFYNVNAFIAFEGFASLGWEIIKFHDVNEMKENN
                     PEDIVVGGIGNVRRRLEKLGIERSQREIDYPDSLSSYFGRKIWTTRI"
     gene            complement(17682..18401)
                     /db_xref="GeneID:87585966"
                     /locus_tag="AA984_RS12880"
                     /old_locus_tag="AA984_12895"
     CDS             complement(17682..18401)
                     /codon_start=1
                     /db_xref="GeneID:87585966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010501900.1"
                     /locus_tag="AA984_RS12880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12895"
                     /product="hypothetical protein"
                     /protein_id="WP_236697868.1"
                     /transl_table=11
                     /translation="MEQELVALACGVCKGVSERIRTECELFDIAGFENDSMEWSDYENE
                     VPPLDERHWLRSNRPPERGQVRTVKVSHPFHMRIGEPFWIMYTPVLSSFNGWDSHPEEI
                     EQSSFVRCSIERVIERNEFKAWLCVKILDVWMIQDYNKRFPERDGREGYLEGFEMFGDP
                     YIFNYQNCLFISAGSQGNIGVWGLVKRIDGQYHMFVYGDWDFHTNNAYGGNILLPKERI
                     DGWLKQAMENNRFETID"
     gene            complement(18514..19092)
                     /db_xref="GeneID:87585967"
                     /locus_tag="AA984_RS12885"
                     /old_locus_tag="AA984_12900"
     CDS             complement(18514..19092)
                     /GO_process="GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007720246.1"
                     /locus_tag="AA984_RS12885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12900"
                     /product="TMEM175 family protein"
                     /protein_id="WP_047070239.1"
                     /transl_table=11
                     /translation="MRANRMEAFSDGVLAIIITIMVLEFKVPEGHDWHSLIELSPKVLS
                     YIFSFIYIGIYWNNHHHLLHMVRTMNGRLMWLNLILLFWLSLIPFTTAWMGESQFAPTP
                     MALYGIILLLAAISYRLLQLAIISQHSGDSAFVKSMGRDWKVKISPVLYLLAILTAYVG
                     PWVSGFFYVLVAAIWVVPEKRIEHILRSE"
     gene            19307..19681
                     /db_xref="GeneID:87585968"
                     /locus_tag="AA984_RS12890"
                     /old_locus_tag="AA984_12905"
     CDS             19307..19681
                     /codon_start=1
                     /db_xref="GeneID:87585968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015894033.1"
                     /locus_tag="AA984_RS12890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12905"
                     /product="hypothetical protein"
                     /protein_id="WP_047070240.1"
                     /transl_table=11
                     /translation="MKTANEILSIISHDSFLENVFHKDVDWEAELDARDADEFDTAWSS
                     SYKKVDEIDPSENTVIREIREFVFKQTFRITQNSELAGYASDDFGLISKAFENKINIEF
                     INNLWDSYLQGNFPNCSICE"
     CDS             complement(19753..>21697)
                     /codon_start=3
                     /db_xref="GeneID:87585969"
                     /inference="COORDINATES: protein motif:HMM:NF019192.5"
                     /locus_tag="AA984_RS12895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_12910"
                     /product="S-layer homology domain-containing protein"
                     /protein_id="WP_052773400.1"
                     /transl_table=11
                     /translation="ALEKANAVLADPNATQQEVDEALAALTKARDGLKKPDEPTPAVDK
                     TKLQAKADEIKAENLQEEEYTSASWAELKQALEKANAVLADPNATQQEVDEALAALTKA
                     RDGLKKPDEPTPAVDKTKLQAKADEIKAENLQEEEYTSASWAELKQALEKANAVLADPN
                     ATQQEVDEALAALTKARDGLKKPDEPTPTVDKTKLQAKADEIKAENLKEEEYTSASWAE
                     LKQALEKADAVLADPNATQQEVDEALSALKKAREGLKKPSVPTPTPTPTVDKSKLQAKA
                     DEIQSENLTGEDYTSESWEELQKALRKADAILADPNATQEEVDKALSALKKAREGLKKP
                     DEPTPTPTVDKSKLQARVDEIDDEDLDEDDYTSSSWRKLEKALKRANDVLEDPDATQDE
                     VDEALAELKKARRDLESVDERDRDRDKERKKDRESTNHVQNPFFTGGSSGNVEPKPSEP
                     AKEENDQTGYMNGYPTGNFDPNRQVTRAEMAMILVNTGMVKTTSASGMFMDVADQHWAA
                     DAIRRANEAGLMNGYANGTFNPGGGITRAEMATIVYKHLGLNGDGMPNNFYDVPADHWA
                     TQIIAAVSKEGYMAGYPDGTFHPQNTLTRAETVTIINRLLNHSQLSTVIGQSWPDVPPT
                     HWAYKDIEAATKK"
     gene            complement(19753..>21701)
                     /db_xref="GeneID:87585969"
                     /locus_tag="AA984_RS12895"
                     /old_locus_tag="AA984_12910"
     assembly_gap    21702..21876
                     /estimated_length=175
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     misc_feature    22268..22282
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
     misc_feature    22680..22695
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.1"
                     /tool="antismash"
     misc_feature    22905..22920
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.85"
                     /tool="antismash"
     misc_feature    22906..22919
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.38"
                     /tool="antismash"
     misc_feature    23130..23145
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.85"
                     /tool="antismash"
     misc_feature    23131..23144
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.38"
                     /tool="antismash"
     misc_feature    23355..23370
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.85"
                     /tool="antismash"
     misc_feature    23356..23369
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.38"
                     /tool="antismash"
     misc_feature    24426..24438
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.88"
                     /tool="antismash"
     misc_feature    24441..24453
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
ORIGIN
        1 tgctgtatgg agctcataat acccttcctt atctactgtt tttgtaaaaa agaagtagta
       61 gctccttgcc ccgttgcaag acgctacgaa aacatcttac ctttcacaac tataactata
      121 tcatagaaat tatttattga ttcaattatc tattataatt agaggattaa taactattta
      181 atgttggtaa aaaagggagg attccgcaaa cagtgcctga tgaacacgta aaaaccattg
      241 ccctgcctca gtttcttgca ggggtttagg atttggtttg ttgttaccag tgaggagctt
      301 accatataaa tttttcgtta caaatggtaa aacctggcag cccattaaaa ccttaatctc
      361 atatctaagg agagatggag atgaactctt tgacccacct gacaaacagc attccatggc
      421 agcgtttgac gacagcctac ggcagaggga cggacattcc gcagctgata gagacccggc
      481 aatatgagga gttggccaat ctaatcgagc accaaagcac cctgtggcag acgacgccgt
      541 gggtgctgct gatactccta caagagctta ccaaacagaa accagagcag gtctcttcgc
      601 aggaaattca gttgtacttg gctgtagctt ctgctataaa cgtggacgaa atggattcac
      661 aaaatgcggt tgagaccatg aacgagctat tggacgaaaa gtacttgtgg ccagaggacg
      721 aggaagacga tgaattatgg tgggaagaag aggagccacg gggttatgag caggaagcat
      781 ttttcagcta ttattccttc agttacttgc tgctaaaaga cgccattccc gttttcaccg
      841 cgattatgag agggaatgat aagctcgctc ccgctattca agagctgctg cttatgcttc
      901 agtcaaagga tgttagaact gtcgaatagg tattcgagtt tctttgatag cacccacccc
      961 cgtcacctta tgatggggca ggtacttcta gctgctgtac gtaatatcga tgggcaactt
     1021 ctgcaatgcg atcctgatct tcccagaagc tctgatcaag cttatccagc cgttcttcct
     1081 cctcctcggt aaggaaccgt ggaatatccc agagttgggt gaggcggtcg tcttccgata
     1141 gatgctcgat gcaggcatat cccgactgga cgatttcaag agcatggact gccccgatgg
     1201 cttgtaaggc ccgtaccgcg tagatatatg cctcttctcc ccagttgcaa aaaaactgca
     1261 aaaacccgcc gttatataca tcagcctcca acaaccataa ggcggcaatc tcttgttcct
     1321 gcgaggtcag tgtgttccag cccaaagcat tctttttctg cacaaaggct gcggcaaaat
     1381 cgaaccatac gtcatgaata tccaccttgc tcaacttgta cgccccctaa atgttaatcc
     1441 cttcaagaac agatgtgcac aaacaacacg aaataaatta atcttatatg aatacataat
     1501 cttttggtag atggtggtag atctgcgtgg ctggcatcta agaaaaagaa tcgtttagga
     1561 ggtttgcaat ggatcaggta cttatcgagc aattaaattg ctggcatgaa gaagacgaac
     1621 accagaaaat tgtggacttg ctgatagccg ttcctgagga gaagcgagag tatgaggcgg
     1681 tcagccgact gggcagagct tataacaact tgggtctata tgaagaagcg ctcaaccaat
     1741 taaagaaaat tactgaagca ggtcaacaag acccagtctg gcactttcga gtaggttatg
     1801 ccctctatca tttgaaaaga tatgaagaag cgggacagtc attccgtacc tcagacaagt
     1861 tagaaaccgg taatcagaac accgaatcat ggttacggtg gagcttgcaa aaagcggaga
     1921 agcagcaaag acaggagctt cggatggctg ccaaaagagc agcggccgtt gagggttccg
     1981 catcggagga agtccctttt tcgaacatgt cacttgaaga cttttgggac gacagcgagt
     2041 acgcgaaaaa ggcatatcaa tccgcgccac ccactgatga actgatcgct tcgatcgagg
     2101 aagagctggg atacaagctc cctgcctcct atcttgcact aatgaagcag cagaatggcg
     2161 gcattccgaa aaacacatgc ttcccaacag aggaccctac ctcctgggct gaggatcaca
     2221 ttgccattac aggcattcta ggcattggcc gagagaaaag ctattcgctc tgtggggatc
     2281 ttggcagtcg gtttatgatt gaggaatggg gatatcccga cattggagtc gtcatctgcg
     2341 attgtccttc agcaggtcat gacctagtca tgctggatta ccgggaatgc ggtagggatg
     2401 gtgaacccga agtcattcac gtcgatcagg aaaacgatta tgagattact ttcctggctg
     2461 aaaatttcga ggcgtttatc agaggcttgg tgagcgaaga agaatacgat acctccgagg
     2521 aggataagga agcggctctt tacaaagtag cccatgggaa attctcttcc ttgctggagg
     2581 agctgtgcac acccgtgtcg gaagtggaac aaattgatca gaaaatacgc ggcatttgta
     2641 cacggattgt agaggagaaa ggctattttt cttttcatgc ggatgaattc tcgtatttga
     2701 tgtatgatgt gcagttttgg ctatacacaa agtcataccc ggataccact cgcgaacagt
     2761 acctggctgt ctatgagaaa atgattgcct ttggcggaga attcgggcaa ggcggctatg
     2821 cgccgggatg gattagcgaa tggctggatc gtcgcaagga ggaaggccgg atcgtacagg
     2881 aaaatggaca catccggttt acagatcagt tcgctgcgga agtgattcaa cagctgcgag
     2941 aagcctaaaa tacatgcaag caacaaagag cccacattgt cgcgggctct tcttttattt
     3001 ccattgattg cgggtgtatc cctgattgct atgcgttcta ctcatgaaaa tcgaggcccg
     3061 atttgacttc tttcacatac cctgcccgaa tcacgaaatc tccgaaatgc tccccttcct
     3121 cacgttcctt cgcataccga tttaagatcg gccgcagttc attcagtatt tctttttctc
     3181 cgatgttttc acgatacagc ttgttcaatc gattgccgga gaaaccgccg cccaaataca
     3241 tgttgtattt accgacagcc ttcccaataa aagagatttc tgcgagtgca ggtcttgcgc
     3301 atccatttgg gcaccctgtc atgcgaatga cgatctcctc atcgcgcaaa cccgcctcat
     3361 ccaagatcag ctcgatctca tccagcagtg taggcaaata acgctctgcc tcagccatcg
     3421 cgagtccgca agtcggcaac gaaacacaag ccatggagtt tctccgcagt gcagaataag
     3481 cagctccatc ggtgagcccg tatgcttgaa tgatctgttc aatttccggt ttcttttcac
     3541 tggtgacatt tccaatgagg agattttgat tcggcgtcag gcggaaatcc cctgtatgca
     3601 ccttggcaat ctcccgcagg ccggacttca ggaggtagtt gtcctcgtct tttacacggc
     3661 cattctgaat gaaaagggta aaatgccagt tatcgtcgct cccttttacc cagccgtagc
     3721 gatcgccatt atgctcgaag tgataggggc gtgcctgctc cagctcccag cccagtcgct
     3781 gctccagttc atggacaaac cattcgatac cgcggtcgtc gattgtatat ttaaaccgag
     3841 catgcttccg caccgcgcga tctccgtagt ccctctggat catgaccgtt ttctcggcga
     3901 catccaatac ttgttccggt gtggcgaaac cgatcacccg cgccacctgc ggatacgttt
     3961 tgggatcgcc gtgggtcatt cccattccgc ctccgaccgc aacattgaag cccagcagtc
     4021 gaccttcctc atgaatggcg ataaagccca aatcctgcga aaaaacgtca acatcattgg
     4081 caggcggaac ggcgatgccg atcttaaact tgcgcggcaa atagacaggc ccgtaaatcg
     4141 gttcttgctc taccccatcc cgactgtcga cgaccttttc ttcatccagc cagatttcat
     4201 gataggcgcg ggtccggggg tccaaatgat tgcttatttt tttggcccat tcgtaaacct
     4261 cttgatgaac ttccgactcg tacggattcg ggttgcacat gacgttgcgg ttgacgtccc
     4321 cacacgcagc cagtgtactt aacaaggcct cgtttacttc ttgaatcacc tgcttcatat
     4381 tccacttaat cacgccatgc agttgaaaag actgacgagt cgtcaggcga atcgttccat
     4441 tcgcaaactt ctgggcgata tcgtccatca taagccattg ctcgggtgtg acaacgccac
     4501 cagcggcacg cacacgcacc atgaattgat aggctggctc cagcttctgt ttgctccgtt
     4561 cgttccgaag atcccggtca tcctgcatgt agctgccatg aaatttcatc aggcggttat
     4621 catcctcagg gatggaccca gaaattctgt cttccagcgt ttccgccaga cttccccgca
     4681 agtaatcgct tcggcgttta atgtcctcta catcgctgtg aggagcactg tttggcgaaa
     4741 gcaaatgatt ttctgacatg gtttcaatct cccctctcat tctttctcaa aactcaatag
     4801 acatctcgct gatagcgttt ttcctgctgc atccgtttca aatacgccac ggcttcctct
     4861 gaatcaagtc cgccctcttt ttgaagaacg gtgactaggg ctgcgtgaac gtcgtgcgcc
     4921 atcttcttct cgtctccgca tacgtataca tgcgccccag cctgcagcca ttggtacagc
     4981 tccttgctct tttcaagcat ccggtgctga acatacactt tttcgcttgt atcccgagag
     5041 aacgcgacat ccatgtgggt tagtacgccc tgtttgagcc aacgctgcca ttcgagctga
     5101 tagagaaaat ctgtggagaa atgctgatcg ccaaagaaaa gccatgtctt gcccgtcgcc
     5161 ccaagctcct cccgttcccc caaaaaggca cggaatggag caacacccgt gccaggcccg
     5221 atcatgatca atgggatgtc ggggttagcc ggaagcttaa agttggggtt atgctgtaca
     5281 aatactggca gtgtatcacc cgtctccaaa cgatccgcga tatagctgga acaaacgcca
     5341 taccgatctc gaccatgagc ctgatagtga acattgcgaa ttgtcagatg aacttcgtct
     5401 gggtaggact tcaaactgct cgagatcgaa tagagacgcg gcggcagctt tctaagtacg
     5461 gagacaaaat ctttggcagg cacacccttc aaatcgtagt cctccaccag atctagcaaa
     5521 tcgcgatttc gaacataatc gcgaagctct tgctctcgcc cttccgcaag cagttcctgc
     5581 aaaccatttc ctgatgatag ctttactgct tgttctaaga gaggcttggt gagaagcgtg
     5641 atttcaaaat gactggacaa ggcctcttcc aacgggagct cttccccgtt cttgttaatc
     5701 gggacaggct cttctggctt ccagcccatt gcgtcaatca gctcacggac aaggccagga
     5761 tgatttttag gatagattcc caaacagtca cccggttcat actcgagatt gcaaccctca
     5821 agggagattt ccaagtgacg ggtttcctta tccgatcccc gtccgttcag attcaagttc
     5881 tccaagacca cagcctgaaa cggattggat cgtgaatatt cggtcagtga ccctgacccg
     5941 atcactgcac cgcccacgaa tgcgcttgca gcagcaactt gggtcgccgt agtttcactg
     6001 agagaagcca ggacctgatt catccattca gaggcttgct cgtcgtaatc cacatcgcaa
     6061 tcgacccggg gagtaagacg cttgccgcct agctcttcca accgcttgtc gaactccttg
     6121 ccagtttggc aaaataattc ataagaggta tcgcccaatg ccagcacaga aaaacgcagg
     6181 ccctccaatt gcggggctct cttgctgtgc aggaattcat ggaaagagag ggcgttgtcc
     6241 ggtggttcac catccccgtg cgtgcttacc acaacaagca ggttttcaac ttttttcaac
     6301 gcattcgtct tgaagtcgct catggaggaa agagttacgt ggaatccgtg ctcctgaagc
     6361 tttccggtca gtaccttggc cagcttttgg ctgttcccgg actgagaacc gaaaagtact
     6421 gtcacctctt tggaaatgac tggcccattc gcggctaaag tggcttgaaa cccagcggcc
     6481 atcggtgctt ccactttgtg aagagctgca agatacccgc tcagccaaac cttttgcacc
     6541 tccgaaagcg taggcagtaa ccgatttagg agctctactt gttcctgact gaaaggactg
     6601 tctgtcacct taagtaccaa cgatatgcac ctcacacgag aaaaaattaa ttccgagtaa
     6661 tcttatatga ttatttactt taagctacca tagtgagtag aacccgagca attggaattc
     6721 attattgtca tcataagttt tactaatcgt tggaaaacaa cataaaaagc ccggttccaa
     6781 gataaggaac cggggtgatc ttcactcatg atttatcgaa aaatagccct cacagaatgt
     6841 gttaaactac cttaaaacaa gcacttctct ataaaaaatg tgaagtgaac atccataaat
     6901 gactttatgg gggcatttga tgaaaccatt gatggtagcg acgattcccg gtggaatcat
     6961 aaccattctt atattttttc tagattactt ccgattgcag cttgtcgaca aatttctcat
     7021 gtttgcggct ttcgtcattg tacctcttgt gattttactt ttgcgctatg acgaaaagaa
     7081 taaacatcaa cgggttattt atgctgcttt aaagctgctt caatatcccg cagcgcttct
     7141 cgccttagcc tctgtaatgg gcagcaaaac gtgggggcta ggaagtacag ccataccagg
     7201 gactctctcg ctcgggtggc tacttttcac attcctgctc ggcatctatg gcctgaccgt
     7261 tattgtgaat cgcaagggaa gaacagagga aatcgcgatt ggcacggggc tcgtttactt
     7321 ttttatcggg ggcatttggt tcactctcta tcagtatcaa tttgacctct tccaggctaa
     7381 gcccacaacg cacgccctga gttcggtcca ctttcatttc tcatctgcaa tcgttccgat
     7441 ttttatcggt ttactgggac gagtcatgac aaagaaaagc tggtatccct gggtcgttgc
     7501 tgtcgatatc attggaccca ttttgatcgc ggtcggaatt attttctcga agccgattga
     7561 gtacattggc gtcaccttgt tcgcctgtaa tattgcgatt tacactactt atctgcttgg
     7621 ttacttgaga aacggctccg tacagaataa gtcgagcttc tttttagtcc tttcctgcat
     7681 ggccttctac acgattgtcg tcgtttccat ttgctatccg ttattgaaaa acatgttttc
     7741 tttaaccata catgatttca ttccgattta cggagcgctg cattcgtttg ggtttgtttt
     7801 atgtgggctg attggatggg tgtacatcat agattctctt aaggaaaaat acaacaagga
     7861 gcaacaggag tgattgccac tacgtgttgc tctttgtttc tgaattacac ttcgcacatc
     7921 ctcttcgtac atgacagcaa cctcttgcct gttggcataa ttgaacctta catagccgtt
     7981 tagctgccga taaaacagtt tgcaaacata ttcgttctca atcgtcagat cagggagaaa
     8041 agcttctcgg aacatgccag ccagctccgg caacgaaagc tgctcctgca ctgggggcaa
     8101 gcgcaaaaag aggtgactcc tcgtctccga ccacggctca taataaaccg ctccctccta
     8161 gtcacttccg tatacctggc gatagatttc gtccagcact ctagcataca tcgcttcgtc
     8221 ttcctgctcc tgccctaata cgttgcggcg gctgcttcac cggtaaggcc gcctcggttc
     8281 atggaagcaa caaagagccc acgctcgacg cgggctcttc ttgtatttca ttctatggag
     8341 gcttcctcac aacctcaaac aacgcctcac ttaccccggc gatagagatc gatgctttta
     8401 aagccctcag ccaagactgt aatcatttca gctcggcgct ttgtccgtgt cccctcttgt
     8461 acagcactat atacataccg cgcccaatcc ttttggtacc cgggcgtgag tgattggtaa
     8521 aaagtgagct cttttggcgc attgcgtaaa tcctcttcta ttttcggcac aaagtctata
     8581 taatcatcga cgcattgact cggtttagat gaagcttttg ccgccttctt tttctcattt
     8641 ttaaacccga caaccgtaaa cacctcattc ataccgacca ttcgattgaa tttgatcgtg
     8701 cttgtcccga tatagccatc ttcatcggcc cctaacccat cgaataattc atcccgatgg
     8761 atataagtcg gatagacttt attccctttc ttgggataag caacgtatag aagccctccc
     8821 tccaataaat agctgtggtc gattaccttc atcatgagct cctgcaagga cttcatatct
     8881 agtacgaagg caaaaatcat gtcatattgc acgtctttca actcatggtc cgcttcttta
     8941 agtacggcta agctctcctc accctccggt gtatgtaaga cagccgtttt ttgatatttt
     9001 tgcaggttca gcttctcaac gattgttttc gacatgatgg atcttcccct ttgatttcat
     9061 gatacggctc ggagccaagc ctagcttact ttcttcctac ccagatatac ataaatacga
     9121 aaccacgtaa cctattcatg taggtaattc tctcgtggaa ttcctcttaa tgtgtaactt
     9181 actggtaaag taccccgaaa ttactcgatt aatctttttc aagagtaata cttccattca
     9241 ttattcgaca ttttttgatt atgtcttgtc acgaaatagc tttatagaaa tacaaattca
     9301 tgtagttctt ttaaaaattt gttcttattt acaacacttt tgtcgagctt tcgcgttgca
     9361 taaaaaactt tactgagata ccaccaaggg ctattactcg ttctctgatc acccactcca
     9421 tatttggaat ttatatgtct agaccaattt cataaatcaa cgatggtata ttttttcaaa
     9481 aaaacaatgt tttgttataa attttacgac atatcgaaat atgttgaaaa tattatgttg
     9541 aattctatcg attcctttgt tttaatcatt ttggaataat tgggtatatt tcccttttat
     9601 cctttgctct ttgtgctcca cattgccagc tctttcactc atcaaaaact attaaaaatt
     9661 gggggaaccg gataatgaac aaagacatgt ttgatttgga tgtacaagta aacgcagtag
     9721 gcactaatgg tgctgaacca aacacgatta gaaccgcact gtgttgggtt accagagtaa
     9781 cttgcaaaag cacttgcact tgcgtatgta cagctatgtg cacaccaggt tgcccattct
     9841 ccgacgagaa ataggatagc accgaactaa aaaccaatgt ggagcacaat cttcttgggt
     9901 cagccagacc ctgttttatg gatagtaaat gcctggtgcc agacgtttct ttcaccagca
     9961 tttactatcc tttccccatt tacaaaagga gggatctaag gtggagcgtc agtcaaaagt
    10021 gaaaaaacac gcaaagaaag aatcccgatc cttttttcga acgatggatt ttttcatgct
    10081 tcgaacgcca ttgttgccta tacatatgtt cctagagtta tgtcaagctg attggaaact
    10141 ggaaaatctc gatccgagaa aacaatccat cattcgtgag tgcctagccg ttgccagtcc
    10201 ttcgttgctt gaatcactaa acaaactgga gcagtctgac cgtgagcagc ttgagcaagt
    10261 tgcaaggagc ttacttcgat atggaatccg aatgagtacg cgttcgacgc catttgggct
    10321 attttccgga atagcctgcg ggcattttga tacaaacacc aatctcctcg taaacaaaat
    10381 ggagcagcat aaaaaacgga gccgccctga catggaatgg ctcctgaaaa tcgttcaatc
    10441 tctggaagag aatctggatg tggtcaagca gctttatgtc cagacaaaca cgatgtatga
    10501 ggttgtaggt aatcgggttt cattgccgta tattacgcgg tacggtcaaa atcaaaatgg
    10561 ctaccaaata gaaaatgtct cgattgcgat gaatgaattg attgcgctcg tcttgcaaaa
    10621 agcaacagaa ccaatcttgt ttatggaatt attccaaatc attaagcaat cgtacccgga
    10681 tacggaagac aaccgaattg aatccttttt gtttcagctg gtcaaaaatg agtttctgtt
    10741 cacaagcctt cgcccgcgtc tcactcattc ctcgccgttt gatcatctgc tggctgtatt
    10801 ggagcgtgtt gaagggattg atgaacggta ccagcaacta ctgtcgatca ggcaggaaat
    10861 caacgcctat gaccagctaa aaattggcca aggagaaaca catttcctct ccacactctc
    10921 caaaatgaaa tcggtagagt catcatcttc gcagttacag gtagatttat cgttgtcaac
    10981 agagcaagtg acgcttccga aatcgattgc caaggatctg agcaaagcag cagaactgct
    11041 gtggagactt tcacccaatc atattggatg gcctcatttg gcggaatatc gggactcttt
    11101 tattgaacga tacggttttg aacgagaagt tcccttgctt gatttgctgg atgaaaacag
    11161 ggggttaggt gctcctgcca cctatgaaaa tcccatgagc aaaagaaact ataccccttc
    11221 tagccatgac aagataaatg aaaaagttct tttgcaattg ttgtcccact cgcttttgac
    11281 aggaagcaag gaaatagaac tgacagacga tctgatcgaa aagctggaac cggtatcacc
    11341 aaaatgggag caagtcccgc tttcgatgga attgtatatc tccctgtttg ccccttcagc
    11401 aaaagccatg gataacggtg attacaccat tcatattggt ggaaataccg gatccatgtt
    11461 ggccggcaaa tcttttggac gattcgctga catgcttgga gagtcgttcg aagaaaagct
    11521 ggagcagatc aatcaggaac accagaaggc atacccggac agtatatttg ctgaagttgt
    11581 ttactttcca cggcacggaa gaatcgccaa tgtcgttctt tcgaagagca agcggaaata
    11641 cgagattttg atcggcgtcc cctcttccga acatcactcc ttaaacattc ccttgtctga
    11701 tttggttgta ggggctacat cggattcctt ctatttaaag tcacgatcca tgaataagga
    11761 agtcattcct gttacaggcc atatgcttaa ctacgtaggc tctgttccca atgtatatcg
    11821 ttttctgtgc gaattaggga tagcaaagca gcgaaattgg atgcctttca gttggggcag
    11881 ctttcgtcat gctcctgtcc tacctcgtct gcgttacgga aagattgtac tggcaccagc
    11941 tacgtggaat gttgaccctg aactattgtc tgtttctaaa aaagatggga aagaaaactg
    12001 gatggaagcc gtgcaaatct ggaaacgaca ataccaagtt ccagattacg tgtatattac
    12061 cgaccatgac aacaagatgc tgctcgatct gaaaagtgag agacatctcg ctgagttgat
    12121 ccgggagctt caaaagctga aatctggtga ggctctcatt ctgacagaag taggtgctga
    12181 gctgaaggac tgtgtagtgg aaggagaaga cggtgtcttt catatggagt gtgtcttccc
    12241 acttgtaaaa aatactcccg tcgaagcatc tgcaaccgaa tcggtttctg tgaccacagg
    12301 ggtacacccc cgccgcgcac ttatttctga tcaagaacga ttgaaaatgc caggcagtga
    12361 ttggctattc tacaagcttt actgtgacga agccagaatg gatgagttca ttgcctttcc
    12421 acttcagtct ttatgcgaaa cgatgcacgt aaaaggggct tgtcaaaagg tattcttcat
    12481 gaggtacacc gatccgaaac cgcatatccg tctgcgtttt caagccgcat ccaccgaagg
    12541 actgcaatcc attttctcag aaatgtatca atggacatat gaaatgcaaa aacaaggcta
    12601 cctgtccaaa acaactatcg atacgtatga ccctgaaatt gaacgatatg gtggacctca
    12661 attgattccc ctagctgagg agctattttt tatggacagt atggttgtgg ctcaatggct
    12721 acaactgcat cgtacaaagc agatgaatat accattggag aaggttgcgg taatcagcat
    12781 catcgacctt ttgcatcaat tcttgcattc gatcgacgaa aagctgagct tcctgaacaa
    12841 aatcatttcg tataaagcct acctggatga tttccgcaca gacagagagt tctacctgaa
    12901 agcgggacgc tacacgaatg attggcaaga gctgaaactg ttagagggtg gttccgttct
    12961 ccaccagctt ttccaagtca gatcagaggc gatcaacaac ttttccacgg tcatgcattc
    13021 actgaaagcc caatcggagc tgtataattc gcaggagcaa atcataggca gtatcatcca
    13081 tctgcatgta aataggctgc ttggaataga tcgtgaacag gaaaggaaag tgatgacctt
    13141 ggcccgccat accctgcaca acttgcgata tttcctattg caagaggaaa gtcaaacaaa
    13201 ggagactgcg catgctttct aatacaaaga gctggcaacc gattcataac gctacgctga
    13261 ttaaaaatat tgagcacgta gtaaagcaag tagcccgtaa gcttcaatat cctcacgagg
    13321 tcttgggcga acctcttccc ggtacagact cgcttgcctc cggtgcaatg ggcatcgtcc
    13381 tcttttatgc ggaattggat cgactgtacc ccgatgagca atgggatgtt gtcgcacata
    13441 actatttggt acatgtacaa accgtgatta acgcagatat gtttaactcg ttttccctgt
    13501 ggagtggttt atccgcagca cccgtggtcg cctctattct agcccgtgat cgaggcagat
    13561 atcaaaactt catcgaaaaa ctgcatattc ttatacagcc tgcgattgat gggttcattg
    13621 accaagctcg agggcgaatc gggaacgatt tattcatccc tgattacgat gtaatagaag
    13681 gattagctgg tatcggtcga tatcttcttt tctttaaaga gcaccctgca tgtaaagaaa
    13741 accttaacaa agtattgtca tatattatac aattaactaa aaatatccat tttaatggcg
    13801 agagtgttcc aggctggcat atcagaagtg agaatcagtt tttggaattt gaaaaaaagc
    13861 gatacccaaa tggcaacttt aatttcggaa tttcccacgg gattgccggt ccgtttgcct
    13921 tgctctctct tgctttatta gagggaatag aggtggaggg acaacgagat gccattagca
    13981 agctatgttc ctattatgag aagtggaaaa cggaagacga gcacgggcca atttggccgg
    14041 agagaatcag ttttgaagaa gaaacatgcg gacagatgca gaaccctttt acctataatg
    14101 catcttggtg ctacggggaa ccaagtatag cacgagtatt gtggctagct ggtcaagcat
    14161 tgggtgacac tgagctccag tctttggctc aacaaactta tctctcactt gttcagcgat
    14221 cagtggaatc gctcggtttc gaatccccga cgttttgtca cggctatgct ggtacacttt
    14281 ggatgctcca acgaatgatg atggacacga gctctgatgc ttttgaagca taccgcgaga
    14341 aactagtaaa ccagattctg agcactttca acgataacca tgcttacgga tttcaagaca
    14401 ttgagcatgg acaattccgg gacctgccag gattgttggt cggtgcagca ggagtagcac
    14461 ttgtcttact aagctgcctg agtttggatg aacccgaatg ggactgtatt ttcttactta
    14521 aatagctgag ttaggggaga ctacatgtac ggaccaacag aagatttgtt taccctaaag
    14581 actgtcatcc agtcttttcg aaactggccg aaaatttttc gccttttctg gactgtacaa
    14641 aaaggatatt ttatcaccat tgtgattctg aatatactcc aagggctgtt ccctgttggt
    14701 atgctgtatg ttacccagga acttgttaac gctgtttcca gtggaataag ccaagatggg
    14761 gatactgtcg taatcagctt ccttttcttc atttccttca ttttagtgaa acaactcgtt
    14821 accctcattc agaattatgt cgaaggattg tttcaatccc tgctatcaaa tcgtctccgt
    14881 gaaatggtgt tggataaagc gaatgcgatg gggttagctg attttgaaaa tgcagaggtg
    14941 caagatcagc taaagcgtgc ccaacaagaa accagctacc gcccctatca gatttttgag
    15001 ctggttctaa gtattgtatc cggtgttatt tctctggttt ctacttcgct gtttctcatc
    15061 ttttggaaat ggtgggttgt tttcattctg gtgttgtttc cgcttatctc cttctattcc
    15121 tatttgcgat taagtcaaca ggagttctat attcgttgga gtagagctga aagggaaaga
    15181 agaggctggt acatcagtca tttattaacc cacgatcgtg catttaagga agtacaaatt
    15241 tataaacttg gctcctatct catcacacaa tttcgcgata tgatcactca gtttttttat
    15301 gaagacaaaa agatcgccac aattcgtttg aagacctcgc ttgttttcga aagtttgacg
    15361 attgcgatga ttggttttat gagctttatc gctataaaag cggcttttct gaaagagatt
    15421 ctgctaggga atttggttag ttatattcag gggattactt taacccaaac gacgtcgcag
    15481 tcgttgatgc attccctgat tggactgtct cagcacaata tgtttgtgga acagctgttc
    15541 ctctttttag aaagaaattc gtctgatcca gtcaaactac agaaagtggc tatcactact
    15601 cctcaagaaa acgacccttt tgttcttgaa agtatcgagt tcgtcaatgt ttcatttaca
    15661 tacccggaaa cagcacgacc cgttcttcaa aacctctctt tcaagataag aaaaggagag
    15721 tcgctggcga ttgtaggcga gaatgggtcc ggtaaaacga cattagtcaa actgcttacc
    15781 ttgttatata aagactatga aggacaaata ctgattaatg gaaccgactt gaacgctttt
    15841 gatatggaac agattcgagc aaaaatcggg gtcgtctttc aagattttat gcagtatgag
    15901 atgtctattc gtaacaatgt cgggttcggt gatctttctc ttcttcacca ggatgacaag
    15961 ctatatcacg cacttgaaaa atcaggcatg cgaagcttgg cagaaggttt tgaacaaggt
    16021 ttggatactc agttgggaaa atggttcaca gaaggtcttc agttatcggg cggacagtgg
    16081 caacgcatcg ccattgctag agctttcctc cgaaatgcag acctctatat tctcgacgaa
    16141 ccaagtgcat cactggaccc tatggcagaa aaagaagtat ttgattcatt taatctgttg
    16201 accaaagagc gaatgggaat atttatttcc caccgttact catccgctca gtatgctgat
    16261 caaatcatgg tactggatca aggaagaatc gttgaatttg gtacccacac cgagttgatt
    16321 cgtttacaac aaaagtatgc cagcttgtat aatctgcaag cgtcaccctt tgtttcccaa
    16381 agttgacaca cactttgcta aaaaggagcg gacgactttg acttttctta cggcgctaat
    16441 gagcagcctt gctcacatcg gagcgattca tatcgcactc atcatcttga ttgtgattgg
    16501 gatatggaaa tggattagca acaagaagaa gaaaaatgat aattctgggg aaagttaatg
    16561 taagcttgag aagagttgaa tcaggatgtc aatatgatcg cgctctacaa tggatacggt
    16621 gaggaaattg gcatgtatgg cggacatgaa tttgttagga tacggacact tggccaattt
    16681 gatgacgaag accgagataa tttttattcc ttgttagaac gtgatggtgt aggataatct
    16741 gcacaatagg ctggcgattc cggtggcaag gcactgtgaa aagtcagcct ttttgatttt
    16801 attttgcctc ctcgggcata gttcgcctca taaactatag gctttttaaa tagtctttag
    16861 tccctgttaa ttctgaccat ctggctgaaa gaagcttcgc atagtttata ggagcgattc
    16921 cataagtccc taaggaatga ccatcattaa cctctacagc ttcatattcc catctcgatc
    16981 aattccaaaa tctaaaccat atgcggctgg cgcatcaata aaatccttaa cagcactttt
    17041 tataacacgt agatctaatt ttgaatccca ggcaccttta tactgcctga catcaagtat
    17101 ttctccatat cgtataaagc aacgccattc cgtcacaaaa tcaacgattt ccgaacacca
    17161 aatattcgta tcctcatgtt gttcaatcaa tcctataaaa tctttatatt cttgtagtcc
    17221 atattttcct gccaaaataa ctagacaaag aatctggata atctatctct ctttggcttc
    17281 tttctatccc taatttttca agacgtcttc tcacgttgcc aataccgcca actactatgt
    17341 cttctggatt attttctttc atttcattaa catcatgaaa cttaatgatc tcccatccta
    17401 atgaagcgaa accttcaaaa gcaataaatg catttacatt gtagaattct ccacttttgt
    17461 ttgcctgtat atacgctctc atccatatcg ccccatcatt tcatatggtt tttcattttt
    17521 aagcagtact aaaatcgttc ggcctacgtt atagctctat attcaaactc ctacctcatg
    17581 cttatcatag cacgacatgg aaaattacag gaaataccta aagcatttgt aaaaaataag
    17641 aaaggagctg cggcggccag ctcctttcac tctctcaaat actaatcaat cgtttcaaaa
    17701 cgattattct ccatcgcctg cttgagccat ccatcgatcc gctccttagg tagcaggatg
    17761 tttcctccat aagcattatt cgtatgaaag tcccaatctc catatacgaa catatggtac
    17821 tgaccatcta ttcgttttac gagtccccat acaccgatat tcccctgtga accagcactg
    17881 ataaatagac agttctggta gttgaatatg taaggatctc caaacatctc aaaaccctct
    17941 aaataacctt cccttccgtc tctttccgga aatctcttgt tgtaatcctg aatcatccat
    18001 acatctaaaa tctttacgca caaccaagct ttaaactcat tccgctcaat tacacgttca
    18061 atggaacacc gtacaaaaga agattgttca atctcttcgg gatgcgaatc ccatccatta
    18121 aaactggaga gtaccggcgt gtacatgatc caaaagggtt cgccaatcct catatggaaa
    18181 ggatgggaga ccttcaccgt tctaacctga cctcgctcag gcgggcgatt agaacgcagc
    18241 caatggcgct catccaacgg gggaacttcg ttttcataat ctgaccattc catactatca
    18301 ttttcgaagc cagcaatatc aaacagctca cattccgttc ttatgcgctc tgatactcct
    18361 ttgcataccc cgcacgctaa ggcaacgagc tcttgttcca tttccttcac cctcatcctt
    18421 tcatctttgg gtctgtaacg acaagctctt gaaaaaaaag tagcctcccg tttggagact
    18481 tcttttcgtt tcctatactt ttctcaggtc caattattcg cttctcaaaa tatgctcgat
    18541 tcgcttttcc ggcacgaccc agatcgcggc aacgagtaca taaaagaagc ccgataccca
    18601 tggacccaca tacgcggtta atatcgcgag caaataaaga acaggagata ttttcacctt
    18661 ccagtccctg cccattgact ttacgaatgc agaatctcca gaatgctggc taatgattgc
    18721 gagctgaagc agcctgtaag aaatcgctgc aagcagaaga atgatcccgt acaatgccat
    18781 cggagtgggc gcaaactggc tttcccccat ccacgcggtc gtgaacggaa taagggatag
    18841 ccagaagagc aatatcaaat tcagccacat gagtcgcccg ttcattgtac gaaccatgtg
    18901 cagcagatga tgatggttgt tccagtagat gccgatataa atgaaactga atatgtagct
    18961 aagaactttt ggacttagtt cgattaacga atgccagtcg tggccttctg gtactttgaa
    19021 ttctaatacc ataatcgtaa tgataattgc cagcacgcca tcgctgaacg cttccatccg
    19081 gtttgctctc atttggtgat cacctttttc ccgctttacg cgctgaattg atctaataga
    19141 tatccatagt ttattctagc ttttcttcat gatgtcaagc acaacctttc cctcattcag
    19201 gatcgtttta acgcagacac ttggccaatt tgatgacgaa gaccgagatc ccattgtcct
    19261 tcaaagtgat tcccattagt atattatggg agggggtagg gttccgttga aaacagcgaa
    19321 tgagatactt tcgataatca gtcatgatag ttttttagag aatgtcttcc ataaagatgt
    19381 tgattgggag gctgaattag acgctaggga cgctgatgaa tttgatacgg catggagttc
    19441 tagttacaaa aaagttgatg aaattgaccc ctctgaaaat accgtgatca gagaaattag
    19501 ggaatttgtg ttcaagcaaa cttttcggat aacccagaat tcagagctgg cagggtatgc
    19561 gtcggacgac tttggtctca tttccaaggc gtttgaaaac aagattaata ttgaatttat
    19621 caataacctg tgggattcct acctgcaagg gaatttcccg aattgcagta tatgtgagta
    19681 gtcgaaaaag accggagaag catataaaat atgcactccg gtcttctttt ggattaggga
    19741 agagagttcc ctttactttt tggttgctgc ttcaatatct ttgtacgccc aatgggttgg
    19801 gggtacatcc ggccagcttt gtcctattac cgtgcttaac tgtgaatggt tcagcaaacg
    19861 attgatgatg gtgaccgttt ctgctcgagt caatgtattt tggggatgga atgtaccatc
    19921 tggatagccg gccatgtagc cttctttact tactgccgca ataatctgag ttgcccagtg
    19981 atctgctggt acatcgtaga agttgttcgg catgccgtct ccatttaatc ccagatgctt
    20041 gtatacaatg gtcgccattt ccgcgcgcgt gattccgcct cccggattga acgtgccatt
    20101 tgcataaccg ttcatcagac ctgcttcatt cgctcttcta atcgcatctg ccgcccaatg
    20161 ttggtcggct acgtccataa acattccact tgcggatgta gtcttgacca ttcctgtgtt
    20221 taccaggatc atagccattt ctgcacgggt cacttggcga tttggatcga agtttccggt
    20281 tggatagccg ttcatgtagc ctgtttggtc gttttcttct tttgctggct cacttggctt
    20341 cggttctaca ttaccggagc tgcctccagt aaagaacggg ttttgaacat gattcgtgct
    20401 ttcccggtct tttttccgtt ctttatcccg gtctctgtct cgttcgtcga cagattctaa
    20461 atctcttctt gcttttttta gctcagccag tgcttcgtct acttcgtctt gggttgcgtc
    20521 aggatcttcc agtacgtcat ttgctcgctt caatgctttt tcgagctttc tccaacttga
    20581 agatgtatag tcatcttcat ccaaatcttc atcgtcgatt tcatctactc ttgcttgcag
    20641 ctttgatttg tcgactgtag gcgttggcgt tggctcgtct ggttttttca acccttctct
    20701 agcctttttc aatgccgaga gcgctttgtc tacttcttct tgagttgcat ttggatcagc
    20761 cagtattgca tccgcttttc tcaaagcttt ttgcagttct tcccagctct cgcttgtgta
    20821 gtcttcaccc gtaagattct cggattggat ttcgtccgct tttgcttgca atttcgattt
    20881 gtcgactgta ggtgttggtg taggcgtagg cacgcttggt tttttcaaac cttctctggc
    20941 ctttttcaat gccgagagcg cttcgtctac ttcttgctgg gttgcatttg gatcagccag
    21001 cactgcatcc gctttttcca atgcctgttt cagttctgcc cagctcgcgc ttgtgtactc
    21061 ttcttctttc aaattctcag ccttgatttc atccgctttg gcttgtagct tcgttttgtc
    21121 gacggtaggc gtaggctcgt ctggtttttt caaaccgtct ctcgcctttg tcagtgccgc
    21181 cagcgcttcg tctacttctt gctgggttgc atttggatca gccagcactg cattcgcttt
    21241 ttccaacgcc tgtttcagtt ctgcccagct cgcgcttgtg tactcttctt cctgcaagtt
    21301 ctcagccttg atttcatctg ctttggcttg cagcttggtt ttgtcgacag caggcgtagg
    21361 ctcgtctggt tttttcaaac cgtctctcgc ctttgtcagt gccgccagcg cttcgtctac
    21421 ttcttgctgg gttgcatttg gatcagccag cactgcattc gctttttcca acgcctgttt
    21481 cagttctgcc cagctcgcgc ttgtgtactc ttcttcctgc aagttctcag ccttgatttc
    21541 atctgctttg gcttgcagct tggttttgtc gacagcaggc gtaggctcgt ctggtttttt
    21601 caaaccgtct ctcgcctttg tcagtgccgc cagcgcttcg tctacttctt gctgggttgc
    21661 atttggatca gccagcactg cattcgcttt ttccaacgcc tnnnnnnnnn nnnnnnnnnn
    21721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnctgt gtttaccagg atcatagcca
    21901 tttctgcacg ggtcacttgg cgatttggat cgaagtttcc ggttggatag ccgttcatgt
    21961 agcctgtttg gtcgttttct tcttttgctg gctcacttgg cttcggttct acattaccgg
    22021 agctgcctcc agtaaagaac gggttttgaa catgattcgt gctttcccgg tcttttttcc
    22081 gttctttatc ccggtctctg tctcgttcgt cgacagattc taaatctctt cttgcttttt
    22141 ttagctcagc cagtgcttcg tctacttcgt cttgggttgc gtcaggatct tccagtacgt
    22201 catttgctcg cttcaatgct ttttcgagct ttctccaact tgaagatgta tagtcatctt
    22261 catccaaatc ttcatcgtcg atttcatcta ctcttgcttg cagctttgat ttgtcgactg
    22321 taggcgttgg cgttggctcg tctggttttt tcaacccttc tctagccttt ttcaatgccg
    22381 agagcgcttt gtctacttct tcttgagttg catttggatc agccagtatt gcatccgctt
    22441 ttctcaaagc tttttgcagt tcttcccagc tctcgcttgt gtagtcttca cccgtaagat
    22501 tctcggattg gatttcgtcc gcttttgctt gcaatttcga tttgtcgact gtaggtgttg
    22561 gtgtaggcgt aggcacgctt ggttttttca aaccttctct ggcctttttc aatgccgaga
    22621 gcgcttcgtc tacttcttgc tgggttgcat ttggatcagc cagcactgca tccgcttttt
    22681 ccaatgcctg tttcagttct gcccagctcg cgcttgtgta ctcttcttct ttcaaattct
    22741 cagccttgat ttcatccgct ttggcttgta gcttcgtttt gtcgacggta ggcgtaggct
    22801 cgtctggttt tttcaaaccg tctctcgcct ttgtcagtgc cgccagcgct tcgtctactt
    22861 cttgctgggt tgcatttgga tcagccagca ctgcattcgc tttttccaac gcctgtttca
    22921 gttctgccca gctcgcgctt gtgtactctt cttcctgcaa gttctcagcc ttgatttcat
    22981 ctgctttggc ttgcagcttg gttttgtcga cagcaggcgt aggctcgtct ggttttttca
    23041 aaccgtctct cgcctttgtc agtgccgcca gcgcttcgtc tacttcttgc tgggttgcat
    23101 ttggatcagc cagcactgca ttcgcttttt ccaacgcctg tttcagttct gcccagctcg
    23161 cgcttgtgta ctcttcttcc tgcaagttct cagccttgat ttcatctgct ttggcttgca
    23221 gcttggtttt gtcgacagca ggcgtaggct cgtctggttt tttcaaaccg tctctcgcct
    23281 ttgtcagtgc cgccagcgct tcgtctactt cttgctgggt tgcatttgga tcagccagca
    23341 ctgcattcgc tttttccaac gcctgtttca gttctgccca gctcgcgctt gtgtactctt
    23401 cttctgtcaa gttctctgcc ttgatttcat ctgctttggc ttgcagcttc gatttatcaa
    23461 cgacaggttc ggttggtgtt gtatctacgg taatagactt tgtcgccttg gctgacttgc
    23521 cgtctattgt cgtcgctgtt acctcaacgg tgtattcacc atcttttaaa tcttgggtag
    23581 gtgtaaacgc ccagttgcct tctgcatcaa ctgttaccgt tggagtatct actacattgc
    23641 cagctttgtc tttaatctca acggtcacct tagatcccgc tgttgacgtt cctttgaaca
    23701 ctggcttcgt tacagtgacc ggattggcac ttggttcagt aattgtaatt gtcgccccag
    23761 aatcctcaac atttttgtta aatggatcta ctggaacacc gtttgtacct tttaagttcc
    23821 ccaagccatc ataagaaatg tttactgctt tatcggaaac attcgtacct gctggcaagg
    23881 tgatcactag ctttgtagaa tcgttttcgt caactttgaa agtgagacca ccgttttcta
    23941 cagctgtacc atcaactgtg attgtaaatc cagttaaatc ggttaactct actcctcgat
    24001 caaacgtcac cgttatttta ttgccatccg ctactgtttc ctcaattgta gcagctgttg
    24061 gtacgggtac agttgcggca atcgtaaaat aatggccatt agcaaattca gcactattaa
    24121 gtgttgctgt gccatctgtt agtggataga atgcatcgtt ttgatcgaat tgctcatcct
    24181 cactaacaac aagatacaaa ggccacccgg aagcacctgc tactttgtct acgtgcagcg
    24241 taatgtctgt atcttgccaa ttcgttttct ctactttata ggtgcgtcca atacgtttta
    24301 gactttctgt atcttttgtg attggagtcc cgaatgtaac gtctccaccg ttatcgctaa
    24361 aaacaaagaa tgatttatct tcagcaatcg tcttggtatt ctgggcattc gtctcttgaa
    24421 tcacattgcc tattgcaagc gtgacattgg caccgtcaac ctgagatttc gattgctttt
    24481 gatacaaagc acctgcttca tcacgaccga tccctgtgat gcggt
//
