LOCUS       NZ_LDCN01000002        22142 bp    DNA     linear   CON 11-DEC-2024
DEFINITION  Brevibacillus formosus strain DSM 9885 Scaffold2, whole genome
            shotgun sequence.
ACCESSION   NZ_LDCN01000002
VERSION     NZ_LDCN01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Brevibacillus formosus
  ORGANISM  Brevibacillus formosus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Brevibacillus.
REFERENCE   1  (bases 1 to 997053)
  AUTHORS   Wang,J.P., Liu,B., Liu,G.H., Chen,Q.Q., Zhu,Y.J., Chen,Z. and
            Che,J.M.
  TITLE     Genome Sequence of Brevibacillus formosus F12T for a
            Genome-Sequencing Project for Genomic Taxonomy and Phylogenomics of
            Bacillus-Like Bacteria
  JOURNAL   Genome Announc 3 (4), e00753-15 (2015)
   PUBMED   26205874
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 997053)
  AUTHORS   Liu,B., Wang,J., Zhu,Y., Liu,G., Chen,Q., Chen,Z., Lan,J., Che,J.,
            Ge,C., Shi,H., Pan,Z. and Liu,X.
  TITLE     Genome sequencing project for genomic taxonomy and phylogenomics of
            Bacillus-like bacteria
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 997053)
  AUTHORS   Liu,B., Wang,J., Zhu,Y., Liu,G., Chen,Q., Chen,Z., Lan,J., Che,J.,
            Ge,C., Shi,H., Pan,Z. and Liu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) Agricultural Biological Resources Research
            Institute, Fujian Academy of Agricultural Sciences, 247 Wusi Road,
            Fuzhou, Fujian 350003, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. May-2015
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001012775.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:34:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,848
            CDSs (total)                      :: 5,688
            Genes (coding)                    :: 5,626
            CDSs (with protein)               :: 5,626
            Genes (RNA)                       :: 160
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 3, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 146
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 27 of 62
            Pseudo Genes (incomplete)         :: 43 of 62
            Pseudo Genes (internal stop)      :: 9 of 62
            Pseudo Genes (multiple problems)  :: 14 of 62
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:55:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 785072
            Orig. end                         :: 807214
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LDCN01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22142
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="opine-like-metallophore"
                     /region_number="4"
                     /rules="(CntL and CntM)"
                     /tool="antismash"
     cand_cluster    1..22142
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(CntL and CntM)"
                     /kind="single"
                     /product="opine-like-metallophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22142
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:12142](+)"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12142
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
     gene            382..1746
                     /db_xref="GeneID:87585141"
                     /locus_tag="AA984_RS08615"
                     /old_locus_tag="AA984_08620"
     CDS             382..1746
                     /codon_start=1
                     /db_xref="GeneID:87585141"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721753.1"
                     /locus_tag="AA984_RS08615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08620"
                     /product="ATP-binding protein"
                     /protein_id="WP_047069332.1"
                     /transl_table=11
                     /translation="MLTHRRYSLKWRLTLFFSSGMLVLLLFLSIFIFFSTSNLVHQHEQ
                     KLLNQKATAIAADLKTEITEEASLTIAYLTRLLTNYADVNQYINISDQNGKEIASIRGA
                     NWTKEPEEYYERTLVAKEPVQLPFTSELLFVQISTTTEALEWYFSILLTILFLSSFFTL
                     LLSAIGGYWLSNWGLKPLDHLIQQIHSIFPQRLSQRIHHHHVETEIYELIHAFNLLLDR
                     MEEAMVYQQRFVTDASHELRTPLSIIEGYVSLLQRWGQHKPEVRNEALAAVEQECKRLF
                     KLIDDLLSLAKLQHTAQLDSSKVVQPLTPLLLEVKQAWEPIFPPQIKLFFEWEEALVLF
                     MDRERIRQLLDILLDNARKYTDKGQVKVRAYGDEDAVHIVVEDTGIGIQAKEIPHLFKR
                     FYRVDKSRTRKRGGSGIGLAIAQAIVADHEGSISIAPSAEKGLIVHVLLKKAGMD"
     gene            1878..2375
                     /db_xref="GeneID:87585142"
                     /locus_tag="AA984_RS08620"
                     /old_locus_tag="AA984_08625"
     CDS             1878..2375
                     /codon_start=1
                     /db_xref="GeneID:87585142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016740593.1"
                     /locus_tag="AA984_RS08620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08625"
                     /product="hypothetical protein"
                     /protein_id="WP_047069333.1"
                     /transl_table=11
                     /translation="MGKAHKYIHSKIEIRQDQMKGFQHPQYVITINDITLNDYLNQNTR
                     SSSFDLLVPPIELFDNRDQQKVLELLSFTNVALPILVCSDDMDFSCIVVAANVEETKDY
                     IIWKTFGYGMDMSKPIHVPPLTFEKDVYREFVEAFKGFIQKYLAHEASLKECPDHISSG
                     ND"
     gene            complement(2464..3360)
                     /db_xref="GeneID:87585143"
                     /locus_tag="AA984_RS08625"
                     /old_locus_tag="AA984_08630"
     CDS             complement(2464..3360)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585143"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017248496.1"
                     /locus_tag="AA984_RS08625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08630"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_047069334.1"
                     /transl_table=11
                     /translation="MELKQLEYFMALCQELNFTRAAEKLGIAQPSLSQQIRLLEHEIGM
                     PLFDRIGKKTVMTEAGKILLHHSYHVFHELSQARAAISELQGLSRGALKIGVLLTVVNY
                     LLPPTVIAFHQRYPKVELSVFGLRTGDIYEGLLRNELDLGIVFLPMEHDDLETIPLYTE
                     NLALGVPVDHQLAKEPFVSLAILKETPSILLPNTYFLRQLIDERCQELGFSPQPVLEMT
                     TMESITNMVGQGVGVTVLSKGYLDYLDDKRIRTIPIQQPDITAQIGIVYRKNKYLCAAS
                     RVFMEQLIASVKRDEGR"
     gene            3488..4171
                     /db_xref="GeneID:87585144"
                     /locus_tag="AA984_RS08630"
                     /old_locus_tag="AA984_08635"
     CDS             3488..4171
                     /codon_start=1
                     /db_xref="GeneID:87585144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016740595.1"
                     /locus_tag="AA984_RS08630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08635"
                     /product="MOSC domain-containing protein"
                     /protein_id="WP_047069335.1"
                     /transl_table=11
                     /translation="MNIEILSINVGKPKQVQYQNKEVSTGIYKTPTTKALYLSFLNLEG
                     DGQADLVHHGGKEKAVCVYPYEHYPFWEAELQRELPIGAFGENLTIRGLIETDVCIGDT
                     FQLGEAVVQVSQPRQPCYKLSVRYGVPEMVLKVQETGYTGFYFRVLKEGQVSHSDVLTM
                     LSRHPKAITVSYANRIMHQEKDNIDGMKKLLEVEELSTNWRATFTKRLSGVEIDTRERM
                     TGNQS"
     gene            4286..4855
                     /db_xref="GeneID:87585145"
                     /locus_tag="AA984_RS08635"
                     /old_locus_tag="AA984_08640"
     CDS             4286..4855
                     /codon_start=1
                     /db_xref="GeneID:87585145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015891107.1"
                     /locus_tag="AA984_RS08635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08640"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_047069336.1"
                     /transl_table=11
                     /translation="MYNNYYHYYQGYYPVLAGWNNNHFRYGWSPHDYNWGHANGNRYWN
                     RYQNTIELRDYGPKPFVVNIEQATKQNNTFRTVLWTGKHLQVTLMSINVGDDIGLENHP
                     NTDQFIRVEEGQGLIRMGDRKDHLDFERRVNDDDAIMIPAGTWHNFINTGNTPLKVYSI
                     YAPPQHPFGTVHETKASAMASEESTQ"
     gene            5008..6828
                     /db_xref="GeneID:87585146"
                     /locus_tag="AA984_RS08640"
                     /old_locus_tag="AA984_08645"
     CDS             5008..6828
                     /codon_start=1
                     /db_xref="GeneID:87585146"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015891114.1"
                     /locus_tag="AA984_RS08640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08645"
                     /product="PAS domain S-box protein"
                     /protein_id="WP_047069337.1"
                     /transl_table=11
                     /translation="MDKEAQRINLRQEQINMNELLQSLVETTTDAISIRDMQGNILFLN
                     SAFEKIYGWTYQDLLKDPYCLVPEDLIQETKEIFHEIKFKGKNITGYETVRQRKNGEIV
                     QVGLTASPLKDTEGRIVGTSVIARDITDRKMAEEALVKSEAKYRILVENTSDVICQYDV
                     HMNNLFVSPSIEHHLGYTPEEFLETNSFDHIHPDDVHIVKDLRSLISMHPQNVQMEIRL
                     RHKNGSWVYWESRCVPIMSESNEVESFLFVSRNITERKQSEEALRKSEEQYRFIAEHTA
                     DFISVIDKYGHVSYSSPSHVKKLGTRQIIFENIHPEDAALVCERFSTMTQFDIPISCEY
                     RYKLENEKWIYLESRGMPFFSSDGGNQYFINITRDITERKQNEELLRRTEKLSVIGELA
                     ASIAHEIRNPLTALKGFIQYLRPTLSGGTTYTDIMLSELDRINFIVSELLVLAKPQTLN
                     VKRIFLHPLIESVVKFLESEANLNNTTINTIFSQIPIAINGEENQVKQVFINILKNSLD
                     AITANGIISIETTCLHNNHVLIRFTDNGCGISQELLPRLGEPFYTTKEKGTGLGLLVSN
                     KIMKDHQGTITISSEINKGTIVEIMFPISK"
     misc_feature    6840..6854
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.38"
                     /tool="antismash"
     gene            6936..7568
                     /db_xref="GeneID:87585147"
                     /locus_tag="AA984_RS08645"
                     /old_locus_tag="AA984_08650"
     CDS             6936..7568
                     /codon_start=1
                     /db_xref="GeneID:87585147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020477522.1"
                     /locus_tag="AA984_RS08645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08650"
                     /product="YitT family protein"
                     /protein_id="WP_047069338.1"
                     /transl_table=11
                     /translation="MWRKFLFHPLAVRYSVFMIGLAVMAFGIGMMIEAHLGVAPWDTLH
                     IGLQKTFGLTIGIWSQIVGAMIILASYIIGKIRPNIGMFLNMFFFGLFIDLFMWLNWIP
                     TGETVVERAILFVVGLLIYTIGTGMYISPRLGAGPRDSFMLALHERMGWGIGKVRIGIE
                     CTVMVLGLLLGGPVSVGTFVTALAIGPLIKQFIPMWERMLAKPYGTA"
     gene            complement(7612..8811)
                     /db_xref="GeneID:87585148"
                     /locus_tag="AA984_RS08650"
                     /old_locus_tag="AA984_08655"
     CDS             complement(7612..8811)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585148"
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015891116.1"
                     /locus_tag="AA984_RS08650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08655"
                     /product="MFS transporter"
                     /protein_id="WP_047069339.1"
                     /transl_table=11
                     /translation="MELSQTTTKKQANKEKSSISLLSLTVGSFAIGMTEFVIMGLLPNV
                     AKDLNVSISSAGQLITMYALGVAVGAPILTVLTHRIPQKKLLCLLMMLFILGNGISVFA
                     PNYEILMGARLITALTHGTFFGVGAVVASSLVSPDKRAAAVSIMMAGLTIANIIGVPLG
                     TFIGQHMGWRASFGSIAIMGIIALIGILVFVPKMRQENTGSITGQITALLKPKLLLYLL
                     IGALGNAGLFTIFTYITPLLTQITGFAEYHVTWILVLFGCGVTIGNIVGGKLADWKLMP
                     SILGLYLAICIILTLFTFTLYNPIAAVLTIFLWGAASFAVFPGLQVRVMNLAQNAPALA
                     STSSHSAGNLGNATGAFVGGWVITHLDITSLPWVGAVLVGLGLILGTASYLAERKLQQS
                     "
     misc_feature    9059..9068
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            9147..10004
                     /db_xref="GeneID:87585149"
                     /locus_tag="AA984_RS08655"
                     /old_locus_tag="AA984_08660"
     CDS             9147..10004
                     /codon_start=1
                     /db_xref="GeneID:87585149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015891117.1"
                     /locus_tag="AA984_RS08655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08660"
                     /product="diaminopimelate epimerase"
                     /protein_id="WP_047069340.1"
                     /transl_table=11
                     /translation="MKREIDFIKFNPTQNMTILVKNNHPAEEYTHIASKIMSYASVHAE
                     QVGFIEKPNKNGAAANLQMAGGEFCGNACMALASLIAHENGLQHDDLTEIVLEASGIDH
                     FVVCQVKRIKDEYFCQVSMPLPKKIEQQSINYDGDEINMVIVRYEDFFHIVIEVDRVNE
                     AVRKRVQSLAKLLGVTGGVSLIGVLLYQPASNELAPLIFVPSLDSMIWESGCGSGTASL
                     GAYLAWKKQGDIAASIRQPGGTIHVTADWQREEVKSLKIEGAVGIVARGKAFIEIQDSK
                     GRTE"
     gene            10001..10807
                     /db_xref="GeneID:87585150"
                     /locus_tag="AA984_RS08660"
                     /old_locus_tag="AA984_08665"
     CDS             10001..10807
                     /codon_start=1
                     /db_xref="GeneID:87585150"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntL"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015891118.1"
                     /locus_tag="AA984_RS08660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08665"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_047069341.1"
                     /sec_met_domain="CntL (E-value: 6e-101, bitscore: 333.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRPEQLHQHLTAFLERFTHLADRYDGTIQHSSELERIIDEYSTF
                     ITDERNKEVWEQLEQPIVNQLNQLVESVRKSSAICVAIMEKYRALKLLKGIADKTDYFQ
                     NIESCIEEEFGSFQVTVDSKVLMVGSGSFPMTPLLIAKRTGAEVVGIDIDEEAIKLGRS
                     VVERLGSGLSIRLEKEFVERLDMTKDATHIIFSSTVANKYDLLEQLHPLTNDQVIVAMR
                     YGNQMKSLFNYPMREVDERKWRLIETILRPDHVFDIALYKKASAAC"
     gene            10826..12142
                     /db_xref="GeneID:87585151"
                     /locus_tag="AA984_RS08665"
                     /old_locus_tag="AA984_08670"
     CDS             10826..12142
                     /codon_start=1
                     /db_xref="GeneID:87585151"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015891119.1"
                     /locus_tag="AA984_RS08665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08670"
                     /product="opine metallophore biosynthesis dehydrogenase"
                     /protein_id="WP_047069343.1"
                     /sec_met_domain="CntM (E-value: 1.4e-189, bitscore: 626.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDMKRILLLGTGPASIQMAVMLKKHWNCCVGIVGRESVRSKSFF
                     TALKQSNLQIRADVQNEKHQKMEGECQIDHVFHGYGNVTGEWDTFILSVTTDAYTEVLQ
                     QINDQVLQQIKCIVLVSPTFGSNSLLRHYVNKVHSNAEIISFSTYLGDTRWFHDKPSNR
                     VITTGVKKKLYIGSTRSPSPNVKILCELFEQLGINLEVMDSPLEAETRNISLYVHPPLF
                     MNAFSLRVIFGEEPIKKYVYKMFPEGPITQDLIRDMLAQWKEITKVVEKLNIKGLNLLK
                     FMTDDNYPVRLESLSRDDIENFVHYETIHQEYLLFIRYTSLLIDPFSEPDSDGRYFDFS
                     AVPIRKLFINREGYWDIPRMPKEDYYRIKIIQGIARYIDISCPTIDRFIETYESKILEA
                     ARTRKGEQLSDAFVVQSFAEDLKMICSEIDTGIGSKKPY"
     gene            12167..13774
                     /db_xref="GeneID:87585152"
                     /gene="cntA"
                     /locus_tag="AA984_RS08670"
                     /old_locus_tag="AA984_08675"
     CDS             12167..13774
                     /codon_start=1
                     /db_xref="GeneID:87585152"
                     /gene="cntA"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721793.1"
                     /locus_tag="AA984_RS08670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08675"
                     /product="staphylopine-dependent metal ABC transporter
                     substrate-binding lipoprotein"
                     /protein_id="WP_047069344.1"
                     /transl_table=11
                     /translation="MTRNMGFLLKTFMVSIVLLVGCSNGDTEKTKSADTGKEIVYATSK
                     DINDMNPHFYSGSMPAQGMVYESLVENTEEGIKPSLAESWEVSEDGKVYTFHLRKNVTF
                     HDGELFNAEAVKKNIEAVQSNASKHSWIKLSTKIVACNVLDEYTVELVLSEPYYPTLVE
                     LSMTRPYVFISPKNFVNGGTKDGVNGYNGTGPYKLTEHKVDQYAVFEANENYWGGAPKV
                     KKITAKVLPAGETTFLALQKGEVNFVFTDDRGANSLDVEAMNQFVESGEHQMIQSQPMN
                     TGIVVANSSKSESPVHEKAVREAFWHAIDRETISKQIFEGTEQAAYTLFSSNVNYANVE
                     LEKRGYDLEKAKKILEEAGWVIGNAGEFRTKNGKPLAMKLYYDVNSSTQKTQAELIQNT
                     VKRIGVQLEIIGEESSSIANRRSTGDYDLLFNQTWGLAYDPQSTIAAFTSKSSYYHTTR
                     GIAQADELYKKIEDVMVSTNEEHRKSLYADILTIVHKEAVFIPITNGRVTILAPKNLQG
                     ISFKQTQFELPFERMYFE"
     gene            13798..14730
                     /db_xref="GeneID:87585153"
                     /gene="opp1B"
                     /locus_tag="AA984_RS08675"
                     /old_locus_tag="AA984_08680"
     CDS             13798..14730
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585153"
                     /gene="opp1B"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014650326.1"
                     /locus_tag="AA984_RS08675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08680"
                     /product="nickel/cobalt ABC transporter permease"
                     /protein_id="WP_047069345.1"
                     /transl_table=11
                     /translation="MGSYIIKRLMLSIPLVLIISFVTFAFIHLSPMDPAEVVLHSQGIP
                     TITDELLAQTRAKLGMDQPFLTRYLNWVASCLQLDFGDSYITGKPVWSMLGPAFLHTVK
                     LTLISSFAIVALSIVLGVACALNAGKWVDKSVRGVSFFLTSMPSYWLAALLIWYFSVKL
                     DLLPTSGMESYKSYILPVVVITISYAGIYFRIIRSSMLSNMNEDYVLYARACGLPEKKI
                     TMHILRNSLQVAISVFCMAIPIILGSTVVVENIFAWPGLGTLSVKSILSRDFPIIQAYV
                     LVLAVVFILFNTVSDIINAALKPKIRDGL"
     gene            14731..15624
                     /db_xref="GeneID:87585154"
                     /gene="cntC"
                     /gene_synonym="opp1C"
                     /locus_tag="AA984_RS08680"
                     /old_locus_tag="AA984_08685"
     CDS             14731..15624
                     /codon_start=1
                     /db_xref="GeneID:87585154"
                     /gene="cntC"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /gene_synonym="opp1C"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009676623.1"
                     /locus_tag="AA984_RS08680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08685"
                     /product="staphylopine uptake ABC transporter permease
                     subunit CntC"
                     /protein_id="WP_047069346.1"
                     /transl_table=11
                     /translation="MKRLQNVWKDKVAVLSLSIITVTTMAGIFAPFVAPHDPAEVHMEL
                     RFASASWEYLLGNDHLGRCVLSRLIYAIRPSMLWVFVALLLSVFIGSIVGVLAGYFRGK
                     TDAFLMRVCDVVLSFPGYVMILAIIGILGVGFENLIIAFVLMKWAWFARIIRTSVMQYT
                     ESDYVKFAKAIGSSNMAIMIRHIVPVALPDIAVISSSSFGSMILQISGFSFLGLGIQAP
                     EAEWGMMLNEARDVMFSRPEFMLAPGLTIVIVVSAINYLSDALQVALDPKLMTSTYKQQ
                     GLEAASTVKLEGKGVA"
     gene            15632..16453
                     /db_xref="GeneID:87585155"
                     /gene="cntD"
                     /locus_tag="AA984_RS08685"
                     /old_locus_tag="AA984_08690"
     CDS             15632..16453
                     /codon_start=1
                     /db_xref="GeneID:87585155"
                     /gene="cntD"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015891123.1"
                     /locus_tag="AA984_RS08685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08690"
                     /product="staphylopine uptake ABC transporter ATP-binding
                     protein CntD"
                     /protein_id="WP_047069518.1"
                     /transl_table=11
                     /translation="MNILEVNNLKIWDSRNDRVIVPNSSFHVKQGSCLAIVGESGSGKS
                     VTCKAIMRLNSAGIRQSGDILLRGENLMELSEQEMRKKRGKQLCMILQNGMRAFDPSCV
                     VGVHLKETLVEHFGWSRDEITTKMKNAMESVMLKDPIEVMNKYPHQLSGGTLQRVMIAL
                     AIVLEPDILIADEPTTALDTISQFEVVEQFLQLRDRLGSSMIFISHDLGIVKLLADEVL
                     VMKEGEIVEKGTTQAIFSEPQHTYTRYLLSSKLAMNQHFKRVMGGVSIAER"
     gene            16440..17183
                     /db_xref="GeneID:87585156"
                     /locus_tag="AA984_RS08690"
                     /old_locus_tag="AA984_08695"
     CDS             16440..17183
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585156"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013915624.1"
                     /locus_tag="AA984_RS08690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08695"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_047069347.1"
                     /transl_table=11
                     /translation="MLSVECVEKSYGRGGLFSREREHVLKNISFECKSGECLGIIGESG
                     SGKSTLGRLLLGIEKPDRGAILFEGKKVEDRKGRTGNISAVFQDYTSSINPLYTVEDAI
                     REPLQMKRKGREDVRSEIDHLLSQVGLDSSYRKKYPHELSGGEAQRVCIARAISTEPRF
                     ILFDEAISSLDGSVQMQVLELLKDLRKRYKIGYIFITHDIQAAAYICDRVMIIRNGEIE
                     EIVKVEQLKDVQSAYTKKLLQMIIA"
     gene            17234..18430
                     /db_xref="GeneID:87585157"
                     /gene="cntE"
                     /locus_tag="AA984_RS08695"
                     /old_locus_tag="AA984_08700"
     CDS             17234..18430
                     /codon_start=1
                     /db_xref="GeneID:87585157"
                     /gene="cntE"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015891125.1"
                     /locus_tag="AA984_RS08695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08700"
                     /product="staphylopine family metallophore export MFS
                     transporter CntE"
                     /protein_id="WP_047069349.1"
                     /transl_table=11
                     /translation="MRGALSWPFLRLYILTLLYFSANSILNVIIPLKGAELGATNTTIG
                     VVMGAYLFTTMFFRPWAGHIIQKYGPIKVLRTILIFNGAALILYTFTELEGFIVARILQ
                     GVCTAFFSMALQLGIIDALPDEDRSQGISLYSLCAYLPGILGPLLALGIWQAGDSSYFT
                     VAMVTIAILTGVVGYSASMDKKVAEPAPGQTEQGATMLGSMSQLVKNPYLCKCSVLMLA
                     ASIIFGAVTTFIPLYAVQINYGNAGIFLMLQAGTVVLSRFVLRKKIPSDGKWRSSFMMG
                     IMLILAVAALSVSFSSLGGAAFLYVGAILMGIAQALLYPTLTTYLTFVLPKTDRNVLIG
                     LFIAMADLGVSLGGVIMGPVADHFSYSFMYMICAILGVTMIIFAYERSKTSVGLQQDR"
     misc_feature    complement(18582..18591)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            18719..19795
                     /db_xref="GeneID:87585158"
                     /locus_tag="AA984_RS08700"
                     /old_locus_tag="AA984_08705"
     CDS             18719..19795
                     /codon_start=1
                     /db_xref="GeneID:87585158"
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016740606.1"
                     /locus_tag="AA984_RS08700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08705"
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="WP_236697840.1"
                     /transl_table=11
                     /translation="MMDQSLNYFEHSGDEGNAIDNGYLKQIFDHLQDGIILMDQERKIM
                     VMNPSAEKMTGWKRGEKVPFCSYCQNRELEPGEERCYLLAKREVPYFLSAMPTYEGRYV
                     DMEMSTAVIYENGEQNRQDVLLVLKDMTVKKKEEEVRISKQVLQKTLEAQENEHKRLAR
                     ELHDGVGQSLYSVSVGIQAIQARLNEKGQFREYMQEIVNELEKAMQDVKLYSLQLRPHS
                     LDQLGLIPTVQHLVSSLNKAHQDVSITFSYSNVSDHFQPILEINLYRVIQEALHNALKY
                     AKATLIEVILYKENDLLTLLIQDNGIGFVRDRVQGGLGLKHMEERVDQMEGTLQIQSVL
                     HEGTLIKVTVVGQGGRAE"
     gene            19792..20436
                     /db_xref="GeneID:87585159"
                     /locus_tag="AA984_RS08705"
                     /old_locus_tag="AA984_08710"
     CDS             19792..20436
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585159"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721808.1"
                     /locus_tag="AA984_RS08705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08710"
                     /product="response regulator transcription factor"
                     /protein_id="WP_047069350.1"
                     /transl_table=11
                     /translation="MIRVLLVDDHTMIRKGLRVLLESYSQIKIVGESHTGNDAILKANQ
                     LEPDVVLMDLSLPNGLDGFTASNEIRKSNPFVKIVILTMHDEEIFVQKAITVGADGYIL
                     KNSHGELLFQAIVEVYRGKRFYRTSVSQEVINLWLKSDARTLPSVLTLREKELVRLIVL
                     GYTNKEMADKLLISVKTVENHKTNIMQKLGLDSKHQLIQYAIKNRYLDLAF"
     gene            20569..21768
                     /db_xref="GeneID:87585160"
                     /locus_tag="AA984_RS08710"
                     /old_locus_tag="AA984_08715"
     CDS             20569..21768
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:87585160"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721811.1"
                     /locus_tag="AA984_RS08710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AA984_08715"
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="WP_047069351.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.3e-11, bitscore:
                     37.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKQVHYTVVIVGAGSAGISVAARIVRASKRLRGQVAIIDPASKH
                     YYQPLWTLVGGGAAKKEESERDLSSLIPAGVDLICDAVTMFQPEQNTLSTRQGTIFSYD
                     YLVVAAGLQLDWEGVKGLKDAVGKDGVCSNYSYQTVESTWEAIQSFKGGSAIFTHPNSP
                     VKCGGAPQKIMYLADDYFRKLHVRNQSEIIFASAKGSIFDVPTYANTLNNVIRRKNIET
                     RYKHNLMEVRADTKEVVFENLDTKEQVVWKYDMLHVTPPMKAPDFIANSALADTGGWVD
                     VDPFTLAHKRYPTIFGIGDCTNLPTSKTGAAIRKQAPVLEKNLLALIDGTPLAAKYNGY
                     TSCPLVTGYNKLVLAEFDYNLTPCETFPFDQSKERFSMYLLKRELLPILYWNGMLKGLM
                     "
     misc_feature    22038..22054
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.42"
                     /tool="antismash"
ORIGIN
        1 aagccgtttg ccatcgagga gttgtttgcc cggattcggg ccttattgcg tcagcgggaa
       61 acaaaagcaa cccaggaaat agtggttggt cgcttacgta tccagcccaa cgcacggcgt
      121 gtgttcctcg atgaagagga aatcatgttg acgccacgcg aatttgattt gctttattat
      181 ctagttcaga acaaggagca agcggtctcg cgagaacaaa ttctcacagc agtttggggg
      241 tttgacttta tggggaatac caacatcgtg gatgtgtata tccggtattt gcggaacaaa
      301 attgagactg atccatccgt taaactgata cataccgttc gaggaatcgg atatacacta
      361 cgagattaaa aggagaacgc agtgcttaca catcgcagat actcactcaa atggagactc
      421 acgctgtttt ttagctcggg catgttggtc ttgcttctct ttttgtccat ttttattttt
      481 ttcagcacct ctaatctcgt ccatcaacat gagcaaaaat tactcaatca gaaggcgacg
      541 gctatcgctg ccgatttgaa aacggaaatc accgaagaag catcactgac gattgcctat
      601 ttgactcgtt tgttaaccaa ttacgccgac gtcaatcaat acataaatat cagtgaccaa
      661 aacggcaagg aaatcgcttc gataagggga gccaattgga caaaagagcc ggaagagtat
      721 tatgaaagga ccttggtcgc aaaagaacct gtacagctgc cgttcacatc ggagcttttg
      781 tttgtgcaaa tttctactac gacagaagcg cttgaatggt atttttccat cttgctcacg
      841 attctttttc tctcttcctt ttttaccttg ctactttcgg cgattggagg ctattggttg
      901 agtaactggg gactgaagcc tctcgatcat cttatccagc aaatccattc cattttccct
      961 caacgtctct cccaacgaat tcaccaccat catgtagaga ctgaaatcta cgagctgatc
     1021 catgccttta atctgttgtt agaccgtatg gaagaagcaa tggtctatca gcagcgattc
     1081 gtcacagatg cctctcatga attgcgtaca ccgctctcga ttattgaagg gtatgtaagt
     1141 cttctgcaaa gatggggaca gcacaagcct gaagtaagga acgaagcact cgctgctgtg
     1201 gagcaggagt gcaagcgact tttcaaactc attgatgacc tgttgtcgct agccaaattg
     1261 cagcataccg ctcaactaga ttcatcgaaa gtcgtgcagc cattaacccc tctgcttctt
     1321 gaagtaaagc aagcgtggga gcccattttc cctccacaaa ttaagctgtt ttttgaatgg
     1381 gaagaagccc ttgtcctttt catggatcgg gagcggattc gccagttgtt ggacatcctt
     1441 ttggacaatg cacggaaata cacagataaa ggacaagtga aggtacgggc atatggggat
     1501 gaagacgccg tgcacattgt ggtagaggat acagggatcg gcattcaagc aaaggaaatt
     1561 ccccatcttt ttaagcgatt ttatcgtgtg gacaaatctc gtacgcgaaa aaggggagga
     1621 agcgggatcg gtctggccat cgcccaagcg attgtcgcag atcacgaggg aagcatctcc
     1681 attgctcctt ccgcggaaaa aggcttgatt gttcatgttt tgttgaagaa agcgggaatg
     1741 gattgacgac atgaatgatg aacgatgggg ctctgtgagc gttccagagc cttcgtttct
     1801 catagtgttc tggtctatga acctgtaaaa tgaaagggag tcaatacata gagtcatcct
     1861 taacggaggt gcttaaagtg ggtaaggccc ataaatacat acatagcaaa atcgaaatac
     1921 gccaagatca gatgaagggt tttcagcatc cccaatatgt cattacaatc aatgacatca
     1981 ctttgaatga ctatttgaat caaaatactc ggagtagttc ttttgattta ttagttccac
     2041 ctatcgaact ttttgataat cgggatcagc aaaaagtcct tgaattgctt tcttttacaa
     2101 atgtagctct tcctattttg gtttgttcgg atgacatgga tttctcttgt atagttgtcg
     2161 ccgcgaatgt agaggagacg aaggattaca tcatttggaa aacgttcggc tatggcatgg
     2221 acatgtcaaa accgatccat gttccgccat taactttcga aaaagacgtg tatagagaat
     2281 ttgttgaagc gttcaaaggt tttattcaaa agtaccttgc gcatgaagca tccttaaaag
     2341 aatgtcctga ccatatttcc tccgggaatg actaaataat gatagagaat acctatcgaa
     2401 atgataaaaa ggatgctatt gaacaatcat tcgcctcgtc ataaactgat cttgactccc
     2461 gcatcatcga ccttcatcac gctttaccga ggcaatcaat tgctccataa aaactcggct
     2521 tgctgcgcac aaatatttgt ttttccggta aacgataccg atttgcgccg tgatatcggg
     2581 ctgttggatc ggtatcgtgc gaatccgttt atcatcgaga tagtcgaggt aacctttcga
     2641 aagtaccgtg accccgacac cttgcccgac catatttgta atggattcca ttgtggtcat
     2701 ttccaaaaca ggctgtggcg agaagcctag ctcctgacac ctttcatcaa tcaactgacg
     2761 caaaaagtag gtgttgggca ataaaatgga gggggtttct ttcaaaatcg caagggaaac
     2821 aaacggttcc ttcgcgagct gatgatccac aggcactcct aatgccagat tttccgtata
     2881 gagcggaatg gtttccaggt cgtcgtgctc cataggcaaa aagacaatcc ccaaatcgag
     2941 ttcgtttctc aaaagtcctt cataaatatc accggttctc aacccgaaaa cagacaattc
     3001 aaccttcgga taacgctggt gaaacgcgat aacagtaggc gggagcaagt aattgacaac
     3061 cgtcagcagt acgccaatct ttaatgcgcc tctgcttaag ccttgcagtt cgctaatcgc
     3121 tgcacgtgcc tgtgacaact catgaaacac atgatagcta tggtgaagca atattttgcc
     3181 tgcttctgtc ataaccgttt ttttgccgat gcgatcaaac aagggcatgc cgatttcatg
     3241 ctcaagcaga cggatttgct gactgagtga aggctgcgca atgcccaatt tctcggctgc
     3301 gcgggtaaaa ttcaactctt ggcacaatgc cataaagtac tctaattgct tgagctccaa
     3361 cgaccatccc tccagcgatt cgtgatctaa caataggttt ttcctattat tataagataa
     3421 atcattatga aatgatatga atgtagtgtg caatgcccac ttccataaaa gaatgaggtg
     3481 atcgcttgtg aatatcgaaa tcctttcaat aaatgtaggg aaacccaaac aggtacagta
     3541 tcaaaacaaa gaggtttcta ccggcattta caaaaccccg accacaaaag ctctttattt
     3601 atcctttttg aacttggagg gggatggaca ggctgatctt gtccaccatg gagggaagga
     3661 aaaggctgta tgcgtctatc cctatgagca ctacccattt tgggaggctg aattacagag
     3721 agagcttcca atcggtgcat tcggagaaaa tctgacaatt cggggattaa tagaaacgga
     3781 tgtttgtatc ggtgatactt ttcaactagg ggaagcggtc gtacaagtca gtcaaccgag
     3841 acagccctgt tacaaattgt ctgtgagata cggtgtacct gaaatggtgc tgaaggtaca
     3901 ggagacaggc tataccggct tctattttcg cgtgttgaaa gaagggcagg tatcgcattc
     3961 agatgttctg acaatgctct cgcgccatcc aaaggcaata acggtatcgt atgcaaaccg
     4021 aatcatgcat caagagaaag acaatatcga tggcatgaaa aagctgttgg aagtagagga
     4081 gctgtccaca aattggcgag cgacctttac caaacgatta tccggcgtgg aaattgatac
     4141 ccgtgaaagg atgactggca accaatcata gctacagcaa ctgaatggga agaaccatct
     4201 gaaattgctc ttcagaatag ttacctgtca tcaggtagcc acatagccta aagggtaaat
     4261 cctttacact ggagaggaga tagggatgta caacaactat taccattact atcaagggta
     4321 ttatcccgtg cttgccggct ggaacaacaa ccattttcgc tatggttgga gtcctcatga
     4381 ttacaactgg ggccatgcaa atgggaatcg atactggaat cgttatcaga ataccatcga
     4441 attgagagat tatggaccaa agccttttgt cgtgaatatt gaacaagcca caaagcaaaa
     4501 caacacattc cgtacagtat tatggacagg gaagcacttg caggtgacac tgatgagtat
     4561 aaatgttgga gacgacatcg gtttagaaaa tcatccgaat acggatcaat ttatccgagt
     4621 ggaagaaggt caaggactta ttcgtatggg ggatcgcaaa gatcatttag attttgaacg
     4681 aagagtcaat gatgacgatg ccatcatgat ccctgcgggc acatggcaca attttatcaa
     4741 tacgggtaat acgccgctta aagtatattc catctacgcg ccacctcagc atccatttgg
     4801 caccgttcat gagacgaaag ccagtgccat ggcttctgag gaaagcactc aataagaatc
     4861 gaatcgatag gaaaaggtgc caaactatgc cgctcctctt taaggggcgg tattttttag
     4921 tgggatagat attttctcaa ggatattttc aacaaacata gaatattaac cttattcaca
     4981 atcttcgttt aaggaaggta taagcctatg gataaagaag ctcagcgaat caaccttaga
     5041 caagaacaga tcaacatgaa cgagctgctt cagtcattgg ttgaaacgac tacggacgcg
     5101 atttcaatca gggacatgca gggtaatata ctttttttga atagtgcttt tgaaaaaatc
     5161 tacggctgga catatcaaga cctcctgaaa gacccgtact gtctcgtacc tgaagatctc
     5221 attcaagaga caaaggaaat tttccacgag attaaattta aaggaaaaaa tattacgggc
     5281 tatgagaccg tgcgtcaacg aaaaaatggt gagatcgttc aggttggtct aaccgcttct
     5341 ccgttaaaag atacggaagg aaggatcgtc ggaacttcag tcatcgccag agatataacg
     5401 gaccgcaaaa tggcggaaga agcactcgtg aaaagcgagg caaagtaccg catcctcgta
     5461 gaaaatacga gcgatgttat ttgtcaatat gatgtacata tgaataacct ttttgtatct
     5521 ccttctatcg agcaccactt gggatacaca ccggaagaat tccttgaaac gaatagtttt
     5581 gatcacattc accccgatga tgttcatatc gtgaaagatc tgcgttcctt aatttctatg
     5641 catccccaaa atgttcaaat ggagatccga ttacgtcata aaaatggatc gtgggtgtat
     5701 tgggagtcgc gttgtgttcc gatcatgtct gagagcaatg aggttgaaag ctttttattc
     5761 gtttcacgca atatcaccga gcgaaaacaa tccgaagaag ccttgcgcaa gagcgaggaa
     5821 cagtatcgat ttattgccga acacacggca gacttcattt ccgtcataga taaatacggt
     5881 cacgtatcgt atagttcacc ttctcatgtg aagaaattag gtacgaggca aattattttt
     5941 gaaaacatac atcctgaaga tgcagcactc gtctgtgagc gattttccac tatgactcag
     6001 ttcgatatcc ctatttcatg tgagtatcga tataaactag aaaacgagaa atggatctac
     6061 ctcgaatcaa gagggatgcc gttttttagc tcagatggcg gaaatcaata cttcatcaac
     6121 attacacgtg acataacgga gaggaagcag aacgaagaac ttcttcgcag aacagagaag
     6181 ttgtccgtaa tcggtgaatt ggctgcaagt atcgcgcacg aaataagaaa tccgcttacg
     6241 gcattgaaag gctttatcca atatttgcgg ccaacactat caggcggcac cacgtataca
     6301 gacataatgt tgtccgagct agatcgaatc aattttatcg tgagtgagct acttgtattg
     6361 gccaaaccgc aaacgctgaa tgtgaagcga atttttttac accctcttat tgaaagtgtg
     6421 gtaaagtttc tcgaatcaga agcaaatcta aacaacacga cgatcaacac aatattcagc
     6481 caaataccga tagcgattaa tggagaagaa aatcaagtaa aacaagtctt tatcaatata
     6541 ttgaagaatt ccctggatgc gatcacggca aatggcataa tcagcataga aaccacatgt
     6601 ctacataata accacgtcct gattcgcttt accgacaatg gatgtggcat ttcccaagag
     6661 ctgctgccca ggcttggcga accgttttat accacgaaag agaaaggaac aggcttaggt
     6721 ttactggtca gcaataaaat aatgaaagat catcaaggaa ccataaccat ctcaagtgag
     6781 atcaacaagg gtaccatcgt ggaaatcatg tttcccattt cgaaatagga aggtgatcct
     6841 tatgaatttg caaatcgttc ttgataaggt agcattcacc aaatctccac ctacaggtac
     6901 tgtaaaagct agaatgatta gagggggaga aaatcatgtg gaggaagttc ctgtttcatc
     6961 cgcttgcagt tcgatacagt gtgtttatga tcggactggc ggtcatggcg tttggcattg
     7021 gcatgatgat tgaggctcat ttaggtgttg caccgtggga tacactgcat atcggattac
     7081 agaagacatt tgggctgacc atcggaatat ggtcgcaaat cgtgggagcc atgatcatcc
     7141 tcgcttccta catcattggc aagatccggc ctaacatagg tatgttttta aacatgtttt
     7201 tcttcgggct gtttattgac ttattcatgt ggctgaactg gattcctaca ggagagaccg
     7261 ttgtggaacg agctattttg ttcgttgttg gtctgctcat ctatacgatc ggtacaggca
     7321 tgtatatttc accgcgtttg ggagctggtc cacgtgacag ttttatgtta gctttacatg
     7381 aacgaatggg atggggcatc ggtaaagtca ggatcggtat cgagtgcacg gtcatggtgt
     7441 tgggcttgtt gcttggcgga cccgtttcgg tgggaacatt tgtgacggcc cttgccatag
     7501 gaccgctgat caagcagttt attccgatgt gggagcgaat gttggcaaaa ccgtacggaa
     7561 cagcttagag cagagtaaaa agaaaaaggg tgctcaaatt gagtaccctt ttcaactttg
     7621 ttgcagcttg cgttcagcca gataggatgc ggttcctaaa atcagaccca gtcctacgag
     7681 cacggcaccg acccatggga gggaagtaat atcaagatgt gtaataaccc atccgccaac
     7741 gaaagcgcca gtcgcatttc ctagatttcc ggcagaatga ctggaagtgg aagcaagcgc
     7801 tggtgcattc tgagcgaggt tcatcacacg tacttgcagc cctggaaata cagcgaaaga
     7861 tgcagcgccc catagaaaaa tggtcaatac ggcagctata ggattataca gcgtaaatgt
     7921 aaagagcgtc agaataatgc atatcgctaa gtaaagtccg agaatggaag gcatcagttt
     7981 ccaatctgca agctttccgc ccacgatatt gccgatggtc actccacagc cgaagagaac
     8041 aagaatccac gttacatgat actcagcaaa accggtaatt tgcgtcagca gtggcgtaat
     8101 atacgtaaat atggtgaata aacctgcatt gcccagcgct ccgatcaaga ggtatagaag
     8161 aagctttggt ttgagaaggg cagtaatttg cccagtgata ctccccgtat tttcttgccg
     8221 catttttggg acgaaaacga gtattccgat cagtgctatt attcccatga tcgcaataga
     8281 gccaaatgag gctcgccacc ccatgtgttg accgatgaaa gtccccagag gcactccaat
     8341 aatattagca atcgtcagac ctgccatcat aatggaaacg gctgcggcac gtttgtcagg
     8401 acttacaaga ctggaagcta caacagcccc aaccccaaag aatgtcccgt gcgtcaaagc
     8461 ggtgatcagg cgtgctccca tcaatatttc gtagttggga gcaaaaacag agattccgtt
     8521 cccaagaata aatagcatca tgaggagaca gagtagcttc ttttggggaa tccggtgagt
     8581 gaggactgtc agtatcggtg caccgacagc tacccctaga gcatacatgg taatgagttg
     8641 acccgcagag gagatactaa cattcaaatc ctttgcaaca ttcggcaaaa gccccatgat
     8701 gacaaactcc gtcatcccaa tagcaaaaga acctacggta agagagagca aagagataga
     8761 cgacttttcc ttgttggcct gtttcttggt agtagtttga gataactcca tgaagtcaat
     8821 acaacctttc tgtacgataa aatcccgttt gtggtgcggg taaagattac ctgttccact
     8881 ttgttaagtc aaggtattct tcttgtatat agggaaaaat cctactagaa aatactagaa
     8941 cacatacctg gaaggggggc gacttcgaga agaggaataa agaactacaa gtgtacagtt
     9001 gacagacacc caaattgtgg ttatgattta ctcgttaata atcgtaatca ttacggttta
     9061 tttttttaag ttttaaatcg taatgattac gtttaatcca agggaatttg ctgttcatca
     9121 aaaatttggt aagagggtag gttgagatga aacgggaaat cgattttata aagtttaatc
     9181 ccacacaaaa tatgaccatt cttgtgaaaa acaatcatcc agctgaagag tatacgcaca
     9241 tcgcgtcaaa aattatgtcc tacgctagtg ttcatgctga acaagtgggt tttatcgaaa
     9301 aaccgaataa aaatggagca gcggcaaatc tgcaaatggc tgggggtgag ttttgcggca
     9361 atgcatgcat ggcattagcg tcgcttatcg cgcatgaaaa tggtctacag catgatgatt
     9421 tgaccgaaat tgttttggaa gcttcgggaa tagatcactt cgttgtttgt caagtaaaaa
     9481 gaatcaaaga tgaatatttc tgccaggttt cgatgcctct tcccaaaaag atcgagcagc
     9541 aatcaatcaa ctatgatggc gacgaaataa acatggtgat tgtgagatat gaagatttct
     9601 ttcacatcgt gattgaagta gatcgggtca atgaggcggt aagaaaacgt gtacaatctt
     9661 tagccaagct gcttggagta actggagggg tgagtttaat cggggtgcta ttgtatcagc
     9721 cagcctcgaa tgaactggct ccacttatct tcgttccgtc attagatagc atgatctggg
     9781 aaagcggctg tgggtcaggt actgcttcac ttggagccta tctggcttgg aaaaaacaag
     9841 gcgatatcgc tgcttccatc agacaacccg gaggcacgat tcatgtaacg gcggattggc
     9901 aaagagaaga agtaaaaagt ctcaaaattg agggtgcagt cggaatcgtg gcacgaggca
     9961 aagcattcat cgagattcaa gatagcaagg ggagaacgga atgaatagac cagaacagtt
    10021 gcatcaacac ttgactgcat ttctagaaag gttcacccat ttagcagatc gatatgacgg
    10081 taccatccaa cacagctcgg agttagagag gatcatcgat gagtattcta ctttcataac
    10141 ggacgaaaga aacaaagaag tctgggagca gctagaacag ccaatcgtaa accaattgaa
    10201 ccagcttgtg gagagtgtaa ggaaatcgtc ggcgatttgc gttgcgatta tggagaaata
    10261 tcgtgcgttg aagctgctaa aagggattgc cgataagacc gactactttc aaaacataga
    10321 atcttgtatt gaagaagaat ttgggagttt tcaagttact gttgattcaa aggtgttgat
    10381 ggtaggttca ggttcctttc ccatgacgcc attgttgatt gcgaagcgga caggagcgga
    10441 agtagtgggg atcgacattg atgaagaggc catcaaacta gggcggagtg ttgtagaaag
    10501 gctgggaagt ggattgtcta tccgcttgga gaaagagttt gtggaacgac ttgatatgac
    10561 gaaggatgca acccatatca tctttagttc aacggttgca aataagtatg acctgttaga
    10621 acaattgcat ccattaacaa atgaccaagt gatcgtggcg atgcgatacg gcaatcaaat
    10681 gaaatccctt tttaactacc ccatgagaga ggtagatgag cggaaatgga ggctgattga
    10741 aaccatcttg cgtcccgacc atgtgtttga tatcgcgttg tataaaaaag catcggctgc
    10801 atgttgatct taaaaggagg tttctatggg tgatatgaaa cgaatcttgc tattgggaac
    10861 aggtcctgct tccattcaaa tggctgtcat gcttaaaaaa cattggaatt gctgtgttgg
    10921 gatcgttggg cgcgagtctg ttcgttccaa atcattcttt actgcactta agcaaagcaa
    10981 tctgcaaatt cgcgcagatg ttcaaaatga gaagcatcaa aagatggaag gcgaatgcca
    11041 aattgatcat gtattccatg ggtatgggaa cgttacaggg gaatgggata ccttcatatt
    11101 atctgtcaca acagatgctt atactgaggt tttacaacaa ataaatgatc aggttttaca
    11161 acaaataaag tgcatcgttt tggtttctcc aacctttggt tccaatagtt tactacgcca
    11221 ttatgtaaac aaggttcatt cgaatgcgga gattatcagt ttttctacat accttggcga
    11281 tacacgctgg ttccatgata agccatcaaa tcgagtgatt acgacagggg ttaagaaaaa
    11341 gctttacatc ggctcgacgc gctctccttc cccgaatgta aaaatacttt gtgagttatt
    11401 tgagcaatta ggtattaatt tggaagtcat ggactctccg ctcgaggcgg aaacgagaaa
    11461 catatcacta tacgtgcatc cgccactgtt tatgaatgct ttctcccttc gtgtgatatt
    11521 tggagaggaa ccaatcaaaa agtacgtata caaaatgttt ccagagggcc ccattacgca
    11581 agatctcata cgcgatatgc tggctcaatg gaaagagatt accaaagtgg tggaaaagct
    11641 caatataaaa gggctcaatt tgctaaagtt catgacggat gacaactatc cggtgagact
    11701 ggaaagtcta tcacgtgatg atatcgaaaa cttcgttcat tatgaaacga ttcatcaaga
    11761 gtatttattg ttcattcggt atacctcact gttgattgat cctttttcag agccagattc
    11821 agacggaaga tacttcgatt tttctgctgt ccccatccgg aaactgttta tcaataggga
    11881 agggtattgg gatatcccgc gcatgccaaa ggaagattac tatcggataa aaatcataca
    11941 gggcattgca agatacatag atatcagctg cccgacgatc gatagattca ttgaaacgta
    12001 cgaaagtaaa attttggagg ccgcgcgaac acgtaagggc gaacagttat cggatgcgtt
    12061 cgttgtgcaa agctttgcgg aagatttgaa gatgatatgc agtgagatcg atacgggtat
    12121 tggatcaaag aaaccatact aacacgcatt ttctggagga aatggcatga caagaaatat
    12181 gggattttta ttaaagactt tcatggtctc catcgttctg ttggtgggct gcagtaacgg
    12241 tgatacggaa aaaacaaagt cagccgatac agggaaagag atcgtgtatg ccacttcgaa
    12301 agatattaac gatatgaacc cgcattttta ttccggctcc atgccagctc aagggatggt
    12361 gtacgaatcg ctggtagaaa atacggaaga ggggatcaaa ccttcgttgg ctgaatcttg
    12421 ggaagtttcc gaagacggaa aagtgtacac gtttcatttg agaaaaaacg tgacgttcca
    12481 cgatggagag ctgttcaatg cggaagcagt gaaaaagaat atcgaagcgg tgcaaagcaa
    12541 tgcaagcaag cattcctgga tcaagttatc aacaaagatc gtggcctgca atgtactcga
    12601 tgaatatacg gttgaactgg tcttatccga accgtattac ccgacgctgg ttgaattgtc
    12661 gatgacaaga ccttatgtat tcatctcgcc aaaaaatttt gtgaacgggg gaaccaaaga
    12721 tggcgttaat ggttataacg gaactggtcc ctataagctc actgagcata aagtcgatca
    12781 gtatgccgtt tttgaagcaa atgaaaatta ttggggcggc gcgcctaaag tgaagaaaat
    12841 cacagcaaaa gtacttcccg caggagaaac tactttcttg gcactccaaa agggagaagt
    12901 caactttgta tttacggatg atcgaggcgc taatagtctc gatgtagaag ccatgaatca
    12961 atttgttgaa tcaggtgaac accaaatgat tcagagtcaa ccaatgaata caggcatagt
    13021 tgtcgctaat agcagcaaat ccgagagccc tgtacatgaa aaggctgtgc gcgaagcgtt
    13081 ttggcatgcg attgacagag agaccatcag taaacaaata tttgaaggta cggaacaagc
    13141 agcctatacc cttttctcgt cgaatgtcaa ttacgccaac gtggaattag aaaagcgggg
    13201 atacgatttg gaaaaagcga agaagatttt ggaggaggca ggctgggtaa tcgggaatgc
    13261 gggcgaattc agaacgaaaa acggaaagcc attagccatg aagctttatt atgatgtaaa
    13321 ttcgtccact caaaaaacgc aggctgaatt gattcaaaat acggtaaaaa ggattggggt
    13381 ccaactggag attattggcg aggagtcttc ttcgattgcg aacagaaggt ctacaggtga
    13441 ctatgacctg ctcttcaatc aaacgtgggg acttgcgtat gatccgcaga gcacaatcgc
    13501 tgcttttact tccaagtctt cctattacca tacgacaaga ggcatcgcgc aagctgatga
    13561 gctctataaa aaaattgaag acgtcatggt gtcgactaat gaagaacata gaaaatcact
    13621 atatgctgat attttgacca ttgtccataa ggaagctgta tttattccga ttacgaatgg
    13681 aagagtcacg atcttggctc ccaaaaacct gcagggtatc tcgtttaagc aaacgcaatt
    13741 cgagcttcca tttgagcgga tgtactttga ataaatacgc aaaaaaggag cttgcttatg
    13801 ggtagctata tcatcaaaag gttaatgcta tcgattcctt tggtcctgat catatcgttt
    13861 gtaacgtttg ccttcattca tctatctccc atggatcctg ccgaagtggt actgcattcg
    13921 caaggcatcc ccacaataac ggatgagtta cttgcgcaaa ccagagcgaa acttgggatg
    13981 gaccaaccct ttttgactcg gtaccttaac tgggttgctt catgcttgca gttagatttt
    14041 ggagattcat atataacggg aaaacccgtg tggtctatgc taggaccagc ctttctccat
    14101 acagtaaagc tgacgttgat ttcgtcattt gccatagttg cgctgtccat cgtattggga
    14161 gtggcatgcg cattgaacgc aggcaaatgg gtggacaaat cagtcagagg cgtttcgttt
    14221 ttcctgacat cgatgccgtc ctattggctc gctgctctgc tgatctggta tttttccgtc
    14281 aagctggatt tgcttccgac aagcggaatg gagtcataca aaagctatat attgcccgtt
    14341 gttgtgatta caatcagcta tgctggcatc tattttcgaa tcatcagaag ttccatgtta
    14401 agcaacatga atgaagacta tgttctctac gcaagggcat gcggtttacc ggagaagaag
    14461 atcacgatgc acattcttag aaattcattg caggtggcca tttccgtatt ttgcatggcg
    14521 attcccatta ttttgggaag cacagtcgtc gtggaaaaca tctttgcttg gccgggactc
    14581 ggaacgctaa gcgtcaaatc catattaagc agggattttc caatcattca agcctatgtt
    14641 cttgtgttgg cagtcgtctt tatcctgttc aacaccgttt ccgacatcat caatgccgca
    14701 ttgaaaccca aaataaggga tggtctctag atgaagcgat tacaaaatgt gtggaaagac
    14761 aaggttgctg tcctatcctt atccattatc acggttacaa ctatggctgg gatatttgcg
    14821 cctttcgttg caccgcatga tcccgcagaa gtacatatgg agcttcgatt tgcatccgca
    14881 tcatgggagt atctcttggg caacgaccac ctagggcgat gcgttttatc cagactcatt
    14941 tacgctattc gtcccagcat gctatgggtc tttgttgcac tgctcctatc tgtattcatt
    15001 gggtcaattg taggggttct tgcgggttac tttcgtggaa aaacagatgc cttcttgatg
    15061 cgcgtttgcg atgtggtcct ttcttttcct ggatatgtca tgatcctggc gatcatcggc
    15121 attttgggag taggttttga aaatttgatc atcgcctttg tattgatgaa atgggcgtgg
    15181 tttgctcgaa tcatcagaac gtcagtcatg caatatacgg aatccgacta tgtaaaattc
    15241 gcaaaggcaa tcggatcgag caatatggca attatgatca ggcacattgt tccggttgca
    15301 ttgcccgaca ttgctgtcat ttcaagcagc tccttcggtt cgatgatttt gcaaatatcg
    15361 ggattttctt tcctcggttt aggcatacaa gcaccggaag cagagtgggg catgatgctg
    15421 aatgaagcga gagacgtcat gttttcacgc ccggaattca tgctagctcc cggtttgacc
    15481 attgtaatcg tcgtttcggc cattaactat ttgtctgatg cgcttcaagt agctttagat
    15541 cccaaattga tgacttctac ctataagcag caaggattag aagctgcttc taccgtgaag
    15601 cttgagggaa agggggtggc ataactggat gatgaacatt ttggaggtaa ataacctgaa
    15661 aatctgggac agccgcaatg atcgagtgat cgttccaaac agttcatttc atgtgaagca
    15721 gggaagctgc ctggccattg ttggagaaag cggaagcggg aagtcggtga cttgcaaggc
    15781 catcatgaga ttgaatagcg ccgggattcg ccaatcggga gacattctat tacgaggaga
    15841 aaacctcatg gagctctcag aacaggagat gaggaaaaag aggggaaagc agctttgcat
    15901 gattttacag aatggcatgc gtgcctttga tccctcttgc gtggtgggcg ttcatctaaa
    15961 ggagacgcta gtggaacatt ttggatggag ccgtgacgaa atcacaacca aaatgaaaaa
    16021 tgccatggaa agcgtcatgc tgaaagaccc gatcgaggta atgaataaat atccccacca
    16081 gctgtcgggt ggaacgctgc agcgggtcat gattgcgctg gccatcgtat tggagcctga
    16141 cattctgatt gctgatgaac ccacgacagc actcgataca atctcgcagt tcgaagtggt
    16201 tgagcagttc ctgcaattgc gcgatcgact aggcagctcc atgatcttca tttctcacga
    16261 tttagggatt gtcaaattat tagcagatga ggttctcgtc atgaaagaag gagaaattgt
    16321 tgaaaaaggg acgacccaag ccatcttctc tgaaccgcag catacctata cccgttactt
    16381 gctctcctcg aagctagcga tgaatcaaca ttttaagagg gtcatgggag gagttagtat
    16441 tgctgagcgt tgagtgtgtg gagaaatcat acggaagggg cggattgttc tcaagggaaa
    16501 gagagcatgt gttgaaaaac attagcttcg aatgcaagtc tggggagtgt ctcggcatca
    16561 tcggagaaag cggaagtggt aaatcaacat taggaagatt gctattgggg attgaaaagc
    16621 ctgatcgagg tgccatcttg tttgagggca aaaaagtaga ggatcgaaaa ggaagaacag
    16681 ggaacatcag cgctgtattt caagattaca cttcttcgat caatccatta tatacggttg
    16741 aggacgccat acgggagcct ttgcaaatga aaagaaaggg acgagaagat gttcgaagcg
    16801 agattgatca tttattaagt caagtagggt tggattcttc ctatcgaaag aaatatcctc
    16861 atgagttatc agggggggag gctcagaggg tatgcatagc gagagccatt tcaacggaac
    16921 cgagattcat tctatttgat gaagcaatca gttcactgga tgggtctgtg caaatgcaag
    16981 tgcttgaatt actaaaggac ttgaggaaac gttacaagat tggctatatc ttcatcaccc
    17041 atgatataca ggctgccgcc tatatatgcg acagagtcat gatcatacga aatggtgaga
    17101 tcgaagagat tgtgaaggtt gaacaattaa aagatgttca atccgcctat acgaagaaac
    17161 tgctgcaaat gattattgcc taaaggaatt ggcaacgaga gtgagcagag gatcagagga
    17221 aggagcaaga actatgagag gggctctgtc ttggccattt ttacgattat acatattgac
    17281 tcttttgtat tttagtgcga actctattct gaatgtcatt attccgttaa agggtgcaga
    17341 gttgggtgcg accaatacaa caatcggagt cgttatggga gcgtatctgt ttacaaccat
    17401 gttttttcgg ccgtgggcag gtcatattat ccaaaaatat ggaccaatca aagtgctccg
    17461 cacgattctt attttcaatg gagcggctct cattttgtat acgtttactg aattagaggg
    17521 ttttattgtt gcccgtattc tgcaaggggt gtgtaccgct tttttctcca tggcattaca
    17581 gttagggatt attgatgcgt tgccggacga ggatcgttct caaggaattt ccctgtattc
    17641 cttatgtgct tatttgcctg gtattcttgg ccctttactc gctttaggca tctggcaagc
    17701 gggggatagc tcttatttta cagttgctat ggtcaccatt gcgatcctta caggagtggt
    17761 gggttatagc gccagcatgg acaaaaaagt ggctgagcct gctccgggtc agactgaaca
    17821 gggagcaacc atgcttggtt ccatgagcca attagtcaaa aacccgtatt tatgtaaatg
    17881 cagcgtcctg atgctggctg catctattat atttggagct gtgacaacct ttataccgct
    17941 gtacgctgta caaatcaact acgggaatgc gggaattttc ctgatgcttc aagcgggtac
    18001 cgtcgtatta tcgcggtttg tattgagaaa gaaaatccct tcagacggca agtggcgttc
    18061 ctcttttatg atgggaatta tgctcattct tgcggtagcg gcgttaagtg taagcttttc
    18121 tagcttgggt ggagcagcct ttctctacgt aggggccata ttaatgggaa tcgctcaagc
    18181 ccttctctat cctacgttaa cgacgtattt gacatttgtt ctgccaaaga cggatcgcaa
    18241 tgtgttaatc gggttattca tagctatggc ggatttgggt gtttctctgg gaggagtcat
    18301 catggggcca gtcgctgatc atttctctta ttcctttatg tatatgatct gtgcaatctt
    18361 aggcgtgacg atgatcattt ttgcctatga acgaagcaaa acttctgttg ggttacaaca
    18421 agacagatga ttttctttgc cgaggctcaa tcgtggaagg aagaaaaggg ttatctgtaa
    18481 atagtggttg gacacgtaag aaaatattca ggtggcaagc ctagtacatg ttaggagatg
    18541 atacctagcg tttactcggc tttttcatat taggatgcga atcaaaaaac agtacctatt
    18601 tgaccatcat ttagcgtcat aaaagatagg ggaaggtacc tatttgaaag gtgcttcccg
    18661 tcttttacga ttgggttata gaagaaatga tctcgatacc attcagtatg gaggaccaat
    18721 gatggatcaa agtctgaatt attttgaaca ctctggtgat gaaggaaacg cgatcgacaa
    18781 cgggtatcta aagcaaatct tcgaccactt gcaagacgga attattctca tggaccagga
    18841 acgaaaaatt atggtgatga acccatccgc agagaaaatg accggttgga aacgaggaga
    18901 aaaggtcccg ttctgctcct actgccaaaa cagagagttg gaaccgggag aagaacgatg
    18961 ttatttgctc gccaaacggg aggttcccta ttttctttct gcgatgccta catatgaagg
    19021 acggtacgta gacatggaga tgagtacggc tgtcatctat gaaaatggtg aacaaaatag
    19081 gcaggatgtc cttttggtct taaaagatat gacggtcaag aaaaaagaag aggaggtcag
    19141 aatctccaag caggtgctgc aaaaaacgct agaagctcaa gaaaatgaac ataagcgcct
    19201 ggcccgggag ctgcatgacg gcgtaggaca atccttgtat tccgtttcgg taggtattca
    19261 agcgattcaa gctcgcctaa acgagaaagg acaattccgg gaatacatgc aagagatcgt
    19321 gaatgagctg gaaaaagcga tgcaagacgt caagctgtat tctctacagc tgcgtccgca
    19381 tagtctcgat caactggggc tgattcctac tgtacaacat cttgtttcca gcttgaacaa
    19441 agcacatcag gatgtttcca ttaccttttc ctacagcaat gtcagcgatc attttcagcc
    19501 aatcttggaa atcaacctgt accgtgtcat ccaagaagcc ttacataatg cactgaaata
    19561 cgcgaaggcg acactcattg aagtcatctt gtacaaggaa aacgacctac tgacgttact
    19621 gattcaggac aacggaatcg gatttgtgcg cgatcgggtt cagggtggtc tgggactcaa
    19681 acatatggaa gaacgagtgg atcagatgga ggggactctt cagattcaat ccgtgctcca
    19741 cgaaggtaca ttgatcaagg taacagtagt aggacaagga gggagagcag agtgatacgg
    19801 gtgcttttgg ttgatgatca cacgatgatt cggaagggat tgcgtgtgct tctcgaaagt
    19861 tactctcaaa taaaaattgt cggagagagt catacaggaa acgatgccat ccttaaagcc
    19921 aatcagctgg aacccgatgt ggtgctgatg gatttgtcat tgccaaatgg gctggatgga
    19981 tttaccgcga gcaatgagat tcgcaagtcg aatcctttcg tgaaaatcgt catattgacc
    20041 atgcatgacg aggagatttt tgtccagaag gctattactg tcggagccga tgggtacatc
    20101 ttaaaaaaca gtcatggcga gctgctgttt caagccattg tggaggtcta tagaggtaag
    20161 cgcttttaca gaacatccgt atcgcaagag gtcatcaatc tatggctgaa atcggatgcc
    20221 aggacgctgc cttctgtatt aacgctgcga gaaaaggagc ttgtcagact cattgtgctt
    20281 ggctatacca ataaggaaat ggcagataag ctgttgatca gcgtcaaaac tgtggagaac
    20341 cacaaaacga atatcatgca gaaactagga ctggattcta agcatcaatt gatccaatac
    20401 gccattaaaa atagatatct cgatctggcg ttttaatcgc atagatcaaa aagtagggga
    20461 cttcccctat atagaaaaaa taacaggcga ataaactgaa tatagtgact acatcgcatg
    20521 aaccatcatc gtacgattgg aaaccatacc gtcggcgaag gaggaactat ggcaaaacaa
    20581 gttcattata cggttgtcat cgtgggagca ggctcagccg gtatctctgt tgctgcccgt
    20641 atcgtccggg cttccaaaag gctcagggga caagtcgcca tcatcgatcc cgcatccaag
    20701 cattattatc agcctctgtg gacattagtc ggagggggcg ccgcgaaaaa ggaggaatcc
    20761 gagcgtgacc tctcctctct cattcccgca ggcgtcgatt tgatttgcga tgcagtcacc
    20821 atgtttcaac cagaacaaaa cacgctcagc acgaggcagg ggaccatctt ttcctatgac
    20881 tacctcgttg ttgctgccgg tctgcaacta gattgggagg gcgtaaaggg tttgaaagat
    20941 gctgttggga aggacggtgt ttgcagcaat tactcatacc aaacggtaga aagtacatgg
    21001 gaagccatcc agagttttaa aggcggctct gccattttta cgcacccgaa ttcacccgta
    21061 aaatgcggcg gagctcctca gaaaatcatg tatctggccg atgactactt tcgcaagtta
    21121 catgttcgca accagtcaga gatcattttt gcatcagcga agggaagtat ttttgacgtt
    21181 cccacgtatg ccaataccct caacaacgtc attcgtcgca agaacatcga aacgagatac
    21241 aagcataacc tgatggaagt gcgggcagat accaaggaag tcgtattcga gaatctggac
    21301 accaaagagc aggtagtatg gaagtatgac atgcttcatg tgacccctcc catgaaagcg
    21361 cccgatttca ttgcaaacag cgcattggca gacacaggag gctgggtcga tgtcgatcca
    21421 tttacgcttg cgcataaaag ataccccact attttcggca tcggcgattg cacgaatctt
    21481 cccacgtcca aaaccggagc tgcgattcgc aaacaagcgc cagttttgga gaaaaacctg
    21541 ctcgcactga tcgatggtac ccctttggct gccaagtaca acggttatac atcctgccca
    21601 ctcgtaacag ggtacaacaa actggtacta gccgaatttg attacaacct gacgccgtgt
    21661 gaaacctttc cttttgacca atctaaagag aggttcagta tgtacctgtt gaaaagagaa
    21721 ctgcttccca tcctttattg gaatggcatg cttaaaggat tgatgtaagg aagtttttaa
    21781 aagaaagggg gagaagcagc ttttgaacga caggaaggta gcgagtagat ggtcaactgt
    21841 cccgtttctt tgtgtaaaaa gaatcgatag acgccctgtt caccttgctt gataagctgc
    21901 caaagctcgt taagtatgtc agcgttttac aagctcatga aaaagcccac cgtccaaaaa
    21961 acacttcgtt ttatccaatc actgctcgaa gtacacgcgg aaaaatcaaa caaaaaacag
    22021 acctgttaaa ggaggaatgc accatgttgt tgcgttactt ttatgatgaa aagctggccc
    22081 atgcatctta tctggtcggc tgccaaaaaa ccggggaggc gattgttatc gatcctgccc
    22141 gc
//
