LOCUS       NZ_KQ040794            26706 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Paenibacillus wulumuqiensis strain Y24 Scaffold5, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ040794
VERSION     NZ_KQ040794.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus wulumuqiensis
  ORGANISM  Paenibacillus wulumuqiensis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1  (bases 1 to 424750)
  AUTHORS   Wu,Q., Zhu,L., Jiang,L., Xu,X., Xu,Q., Zhang,Z. and Huang,H.
  TITLE     Genome Sequence of Paenibacillus wulumuqiensis sp. nov., a
            Bioflocculant-Producing Species
  JOURNAL   Genome Announc 3 (4), e00795-15 (2015)
   PUBMED   26184946
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 424750)
  AUTHORS   Wu,Q., Jiang,L. and Xu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2015) College of Biotechnology and Pharmaceutical
            Engineering, Nanjing Tech University, No. 30 South Puzhu Road,
            Nanjing, Jiangsu 211816, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000971965.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 14:25:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,570
            CDSs (total)                      :: 4,478
            Genes (coding)                    :: 4,431
            CDSs (with protein)               :: 4,431
            Genes (RNA)                       :: 92
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 10 of 47
            Pseudo Genes (incomplete)         :: 37 of 47
            Pseudo Genes (internal stop)      :: 6 of 47
            Pseudo Genes (multiple problems)  :: 6 of 47
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:39:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 398044
            Orig. end                         :: 424750
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ040794.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26706
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="2"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..26706
                     /SMILES="NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26706
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>26706](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>26706
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    complement(6..20)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.19"
                     /tool="antismash"
     gene            651..1907
                     /locus_tag="WH45_RS06730"
     CDS             651..1907
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811885.1"
                     /locus_tag="WH45_RS06730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF58 domain-containing protein"
                     /protein_id="WP_046213612.1"
                     /transl_table=11
                     /translation="MRALFSYLRLNLQRQHQPSKLWLVVLVWIGCLLYMLFQGGKTSVM
                     LFSMVTLLSLYLIGGGFRGVGRARGSRHLSIGGDHSEIIHAGDQVQVRLSVTIPGFLPL
                     PYVIVRETLKRHNGESWSFEESLIPSMRGKGELLFQTPPLERGRYRFYGTECISEDIFG
                     LLENKGKFNAPGEFLVLPRTAFVPYWEMGSRHSRLGGQQTSQLMSRPETNQINGVRDYV
                     YGDRISRIHWNATARTGIWKSKEFEHEALPKTVIVLDGMADHYESGTQFELAVSVASSM
                     LEYGMRERMGMGLFTIGEDNYSFLPTDQAADWHRMQVHLVDIMADGRGELLDKLERDAR
                     LFPAGSLFVLISPLRGDKAWEIFQFARMRQMNPVQIRIEGKEQESAGQEPAVDHIRGVA
                     SYALNSLDQLPVVLGGRAL"
     gene            1904..4123
                     /locus_tag="WH45_RS06735"
     CDS             1904..4123
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019912526.1"
                     /locus_tag="WH45_RS06735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transglutaminase domain-containing protein"
                     /protein_id="WP_046213613.1"
                     /transl_table=11
                     /translation="MIKWWSGIRSSWYYSLCLLWVMIIAYQWIQYAADIWYTETTLLVL
                     GTMAAVAVIDIVLPVNAWYRLLIKLVAVIVVVYYALDYYGIYHWQPGESPMANLELFIE
                     TLRSYVWFVISAWVLLEVSARIGTSRRAIIMFVGTNIIALAVLDSFTAATLWQEVAWVV
                     FAGMGWLVSNHFRYFQERFPKGWKHLRKYPLKIMFNIAVIFSIVLLAGINMPEIQPTLK
                     DPYTAWKNWRGESVITINGSSPLDGQGASSGYSREDSNLGGGFNFDYTPVMTVSTTSRS
                     YWRGETRLAYSGTGWIDRSGNGWRELDPVKAGDELSLDESSDEDKRSVKQQVKMLSDNN
                     TTYPVLFGAYTIARIEDVNGGDDTSQLDWRSNNGEVHWSQTRQNRQYPESYSLVSRVPV
                     VPVADLEKETYNQLYAGKSLEPYLQVPSDFPKRVKDLAKEVTASAETPYRKIELLQQYL
                     QNNYAYTNNPDLSRQKSSDFVDSFLFEIKEGYCDYYSTAMVMMARSLDIPARWVKGYAP
                     GQASGYVTNDYFPDGATEYTVTNADAHSWAEIYFAGYGWIPVEATPGFDMPLLTESVQT
                     PAATPDTPEQEETAPQPEAEDTKAPVQASDRAVSPAVVWTAAVLVAAWTGFMLYRYRRQ
                     LKAAYTRIRYGEPMTPQQKIMAESKRWLSWMKRHGMDRQSHETLRESVSRWREMRPELS
                     GVLDPLLALFERAKYSPEVVTEDEWVSMKQHLQDLRKLWRKSAAK"
     gene            4308..4835
                     /locus_tag="WH45_RS06740"
     CDS             4308..4835
                     /GO_function="GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811883.1"
                     /locus_tag="WH45_RS06740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="WP_046213614.1"
                     /sec_met_domain="HAD_2 (E-value: 5e-09, bitscore: 31.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFELLIPKLRVNTVFDIDLEKLYAQGYRGIITDLDNTLVGAKSPT
                     ATPELIEWFAKVKKYGFELIIVSNNKMDRVSLFATPLDIKFVHAARKPSNAPFRKAMKL
                     MNCRDDQTIVVGDQLLTDVYGGNRLGLFTVLVLPIALNEEGWRTRFNRQVERLARTRLR
                     KKGLWAEEERNK"
     gene            4832..5959
                     /gene="yqeH"
                     /locus_tag="WH45_RS06745"
     CDS             4832..5959
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yqeH"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345303.1"
                     /locus_tag="WH45_RS06745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="WP_046213615.1"
                     /transl_table=11
                     /translation="MTELSGLTAGTKCSGCGIVLQNESPDHPGYIPAQALERTPLLCQR
                     CFRIRNYNESSTVTVDQSEFLRLLGQVGEQDALVIHIVDLFDFHGSVISGLQRFVGNNP
                     VVLAVNKIDLLPKVTNWNKLRNWVQKEAKELGLKVEDIVLCSAKQNTGFDRLLDIVGSM
                     RGDRDVYVVGATNVGKSTLINRLISDYSDLEEELTTSRYPGTTLDTVNIPLDDGHYIID
                     TPGIVYESRYTELVNKQDLAAIMPDKPLKPLVYQLNQGQSLFFGAMVRFDYIQGGRQSF
                     TLYLNNRLKIHRTKLERADELYANHAGEMLAPPVKADLDKLPAWTRHELRIPKGKPTDI
                     FISGLGWIKANSTDGALVAVHLPKGVKVMMRPSLI"
     gene            5992..6864
                     /locus_tag="WH45_RS06750"
     CDS             5992..6864
                     /EC_number="1.1.1.25"
                     /GO_function="GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA]"
                     /GO_process="GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811881.1"
                     /locus_tag="WH45_RS06750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="shikimate dehydrogenase"
                     /protein_id="WP_200897664.1"
                     /transl_table=11
                     /translation="MTDRNQANKQAALLLGVMGDPIAHSMSPVMHNIALEAAGLPGMYV
                     PLHVKPDHLAEAVTGARALGFTGFNVTIPHKVEIMKLLDELDESAVSCGAVNTVVIRDG
                     RMKGYNTDGIGYVRSLREEAGELADKRVTVLGAGGAARGIVYALLKENVAGITLINRTV
                     DKAAQLIRELNASDAQMQTATYEELAEYLPQTDILINTTSIGMHPNMDETPVAAELIPE
                     GIIVSDLIYNPMETRLLREARARGCRTVGGLGMFIYQGAYAYEYWTGQEAPVSLMHSAV
                     LEALNHANH"
     gene            6886..7182
                     /gene="yhbY"
                     /locus_tag="WH45_RS06755"
     CDS             6886..7182
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="yhbY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372202.1"
                     /locus_tag="WH45_RS06755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="WP_046213616.1"
                     /transl_table=11
                     /translation="MLTGKQKRYLRSQAHHLDPIFQIGKAGMNEGIVRHVLDAIETREL
                     MKVSVLNNCLEEPKDLAEQLAEGTGAELVQVIGRTIILYKESKDHKQIELPRG"
     gene            7238..7831
                     /gene="nadD"
                     /locus_tag="WH45_RS06760"
     CDS             7238..7831
                     /EC_number="2.7.7.18"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nadD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811879.1"
                     /locus_tag="WH45_RS06760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="WP_046213617.1"
                     /sec_met_domain="CTP_transf_like (E-value: 1.3e-32,
                     bitscore: 107.5, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGIMGGTFDPVHIGHMLAAEAALEGCELDEVWFMPSHIPPHKH
                     AAGVSGEQRLEMVEHAIGTNPAFRTLDIELVRGGVSYTIETIRALQERYDQHEFYFIIG
                     ADMVNSLTEWHGIEELARRLTFVGVGRPGSVIHTETMPAYLQPRVVLVNMPQVDISSTD
                     IRERLAAGKTVRYMVHDHVYEYIKRSGLYESDTR"
     gene            7812..8396
                     /gene="yqeK"
                     /locus_tag="WH45_RS06765"
     CDS             7812..8396
                     /EC_number="3.6.1.41"
                     /codon_start=1
                     /gene="yqeK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811878.1"
                     /locus_tag="WH45_RS06765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="WP_082096566.1"
                     /transl_table=11
                     /translation="MNLTRAELIQSVSSQMPEKRWRHTEGVMQSAVVLARRYGADPDKA
                     DLAAILHDVAKYWPSDRQEQLLRDKALNDELLLYDKPLWHAEIGAYVAETEYGIEDTEI
                     LNAIRYHTSGRVGMTTLEKVICLADYIEPGRDFPGVDHIRRLAETSLEAGLVAGFDSTI
                     NLLLARRQVIYPLTVLSRNDLVKQLELEGEL"
     gene            8397..8744
                     /gene="rsfS"
                     /locus_tag="WH45_RS06770"
     CDS             8397..8744
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsfS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821636.1"
                     /locus_tag="WH45_RS06770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribosome silencing factor"
                     /protein_id="WP_046213618.1"
                     /transl_table=11
                     /translation="MALNPEQLLQMTIDAAESIKAHDLVALDLRGISLVADYFVICHGN
                     SDTQVQSIASEVRKRAHDANVVIRGIEGVNAARWVLIDLGDVVVHIFHRDEREYYNIER
                     LWSDAKVVEKV"
     gene            8741..9661
                     /locus_tag="WH45_RS06775"
     CDS             8741..9661
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224181.1"
                     /locus_tag="WH45_RS06775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="WP_046213619.1"
                     /transl_table=11
                     /translation="MSLEAGTIVTLPIGREVSPYGFFLTDGEQEVLMHYSELIGKVKVG
                     DRVEAFIFHDTEDRLAATMKKPLLTLGELGKLKIADLHPRLGAFLEMGLGRQLLLPMSE
                     LPEKPELRPQIGDEVYVVMQHDRQGRLLARLAGEEEFNPLVFHAPTSWMNEWVEALVYK
                     PLQMGTFVLVDGGVLGFGVLGLIHQNERSRMLRLGERVKVRVTQVREEDGRVNLSMIQR
                     KEIGRDEDSQRLLSFMLDRPDKAMPYSDRTPPDVIKQRFGISKAAFKRALGKLMKEGVV
                     VQDQNWTRIVDKDAPAAEGTQESQQ"
     gene            9756..10556
                     /locus_tag="WH45_RS06780"
     CDS             9756..10556
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017687191.1"
                     /locus_tag="WH45_RS06780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_046213665.1"
                     /transl_table=11
                     /translation="MQKQGRTVKAVPYRKFAYVYDELMEDMPYPDWLRFVREAWDRYGM
                     PRTVAELGCGTGSITIPLVNSGFRMTGIDLSSDMLSVARDKMESTSQGHRLFQDGSVQW
                     ICQNMTSWQLPEPVDSVISFCDCLNYLTEPEDIVHTFQSTYAGLKPGGTFIFDVHHPST
                     LRRYDEEQPFMLDDRSISYLWTCEYDTARTEIEHHLTIFARVNEDSQSLYERFEEIHVQ
                     RAYEQDWLRTELYKAGFRDVKCYADFEWIEASDDAARLFFIAVK"
     misc_feature    10786..10800
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.4"
                     /tool="antismash"
     misc_feature    complement(10841..10852)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.67"
                     /tool="antismash"
     misc_feature    10846..10860
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.28"
                     /tool="antismash"
     gene            10861..11889
                     /locus_tag="WH45_RS06785"
     CDS             10861..11889
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /locus_tag="WH45_RS06785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diguanylate cyclase"
                     /protein_id="WP_324292921.1"
                     /transl_table=11
                     /translation="MDQKLQRVNWMIPVLAGVFAGLLGICMMSFFSIRFSTGDNTVMVD
                     FRQLAIMISFYYGGAWSGLISAIMIGVYRLFSGEPLQFSSWVGFGNAMFTYVVTSLCMR
                     GPRETSLKIWFRAIIATLLVYIVAVTILQAITHIELNLFFGLLYICAGLFAYYIIRYIQ
                     RADDTLTMTREAANHDFLTQLYNPRAFDRLFRQTIVDAREHQRSFALLVVDIDFFKKIN
                     DSYGHLNGDTVLVQVAEVLGRTIRPGDYCARKGGEEFAVILNECDERQAVELAEEIRTA
                     MEQHTFVLEEGQSIQLTVSIGVSCYPLTAPEQLFPEADRALYQAKENGRNRVALADCTP
                     AE"
     misc_feature    complement(10866..10875)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     gene            complement(12013..14088)
                     /locus_tag="WH45_RS06790"
     CDS             complement(12013..14088)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811873.1"
                     /locus_tag="WH45_RS06790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_046213620.1"
                     /transl_table=11
                     /translation="MSAYTQQPDGVFKTVCSLDCPDQCGLLIHKENGKITKIAGDPEHP
                     VTRGNICNKVRHMAERIYDDQRLTQPLKRIGPKGSRQFEPITWTEAIEMITSRWKGLIE
                     EHGPETILPYSFYGNMGNINAEGMDRRFFHRLGASQLERTICTAAGGAGFKYTMGGSIG
                     TDPEDTVHTRLFILWGINAVSTNMHQITLAQQARKQGAKIVVIDVHRNQTGRMADWFIP
                     ILPGTDTALALGLMHVLFAENRVDEHFLHEYTIGHEQLREHVKSYDPVTVSGITGVPVD
                     DIYKLARMYSETAPSMIRIGNGLQHHDNGGMNTRAITCLSVLTGQWLVRGGGAIRSNSA
                     YLAHNAAALQRPDLLHNRNTRSFNMNQLGRALTAAEPPVYSLYVYSCNPAVVAPRAAQV
                     REGLEREDLFTVVHDLFLTETAAYADIVLPATSAFENLDFYTSYWHHYIQIGQPVIENY
                     GQSKSNTEVFRLLAAAMGFEEQALQDSDEQMIRQALAHPGNPHLQGIDYEGLLDHQYLK
                     ANRATIYPERLDTPSGKVELYSSTMLQHGLPPLPTYIPLQEQDSHSYIFIPGPTHNFLN
                     STFSNNAKHAGMEKLPRLFMNTADAEREGIVDGDTVIVSNRYGSCELIAAVGETVLPGV
                     VVSQGLWADTPDHQPSHLVNALTPDRLSDMGGGATFFSGRVDLQKKQAFIPAESFG"
     misc_feature    14120..14136
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.56"
                     /tool="antismash"
     gene            14968..15669
                     /locus_tag="WH45_RS06795"
     CDS             14968..15669
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811872.1"
                     /locus_tag="WH45_RS06795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_046213621.1"
                     /transl_table=11
                     /translation="MNNRILLIEDDVSISELIQTQFAKEGFDISCAYDGEQALQAFSED
                     IFDIILLDLMLPKLDGIEILKIIRSQSMVPILIMSAKDGDLDKALGLGFGADDYISKPF
                     SMIELTARVKANIRRALQYSNPVITTVTKEKIHVGELDLDTDNFAVYKSEDEIKLTAKE
                     FQILKLFMTNPKKVFTKAQLYNLVWGEDYYGDNNVINVHMRRLREKIEDDPSTPRYIKT
                     LWGIGYKLGEF"
     gene            15670..16608
                     /locus_tag="WH45_RS06800"
     CDS             15670..16608
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007086407.1"
                     /locus_tag="WH45_RS06800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase KdpD"
                     /protein_id="WP_046213622.1"
                     /transl_table=11
                     /translation="MDIILGLVIIMLVLLVLFQHHRYKQQQANLLYACTKLQAITNQHT
                     DEKLLLHTEDIHLKTLLNEINRLLEQNQKTVASYYQMEISIRKMLSNISHDLRTPLTVV
                     LGYIEVILNDPTLTRSQVDVLLAKVHDKTIEVLSLMKKFFDLVKLESGDHDIEISKIDV
                     SEICKANILSFYDILTAQDIEVVIDIPDDKHYMAYGNEEELNRILNNLLSNAVQYGSEG
                     RVLGLSVHQQNQHICIDVWDKGKGISEKHKDRVFERMYTLEDSRNRLYQGSGLGLTITK
                     RLVEKMGGEISFVSKPYEKTVFTVMLKRYTT"
     gene            16770..17693
                     /locus_tag="WH45_RS06805"
     CDS             16770..17693
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429312.1"
                     /locus_tag="WH45_RS06805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_046213623.1"
                     /transl_table=11
                     /translation="MTYLIKTHQLSKSYDGHEVVSNLNMSVKKGEIYGFLGPNGAGKTT
                     VMKMMTNLIKPTSGEIEIFGEKVTEHSYEMLKRIGSIIEFPVFYEKLSARENLQLHCEY
                     AGYYDHQAIEEALTLVNLQDVNNKPVKSFSLGMRQRLGIARAIMTKPELLILDEPINGL
                     DPIGIKELRSLFQMLCHEYRITMIISSHILSEVEQIADTIGVINKGQLIEEITVKEIHE
                     RNTEYIEILSDDVKKAVYVLEEVLCIDNFKVIDDSRIRIYNLSITQAEISKQFIINGVN
                     IEEMKKKSHSLEDYFVNLLDGGLKHA"
     gene            17686..18378
                     /locus_tag="WH45_RS06810"
     CDS             17686..18378
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007086405.1"
                     /locus_tag="WH45_RS06810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_046213624.1"
                     /transl_table=11
                     /translation="MLKLLRLEIKKYHLWRYMKGVIIANLCFLSLLVLIYVLEKNDGNI
                     PFESYDMAFSIIGSVVRATFTVFAAVLITRLFLEEYKTKSISVLFMYPIKRQKIMLAKV
                     LLIIIFTFATILLSNILMGSIFYLMNKVLHFLAEPMTSDIFMRNALSVLISAAASAGIG
                     LIPLYIGMRRKSVPATLVSAVLIVGFTSATSNDFSMFAITAVPVSLAAVGLLSAYLSIR
                     NVETTDIA"
     gene            18445..18786
                     /locus_tag="WH45_RS06815"
     CDS             18445..18786
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016100924.1"
                     /locus_tag="WH45_RS06815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_082096570.1"
                     /transl_table=11
                     /translation="MNAQFKKGALELCVLVLLLHKDHYGYELVRQISEDIDIARGTLYP
                     LLKKMQKDQYLSTYFVSSTEGPQRKYYAITYLGKERMESLLQEWMHFSESVTRILQKNC
                     VLSKGEEGF"
     gene            18783..19685
                     /locus_tag="WH45_RS06820"
     CDS             18783..19685
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024743.5"
                     /locus_tag="WH45_RS06820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_046213626.1"
                     /transl_table=11
                     /translation="MKRSISILVTVIIIVAILVIGYLVYNRVTGAVTIHEEKTLSASAI
                     TSLKIDTSSANVEVLPGDGENIVATLDGEISPRLEGKYTFNMTPEQNVANIQLNMGNNV
                     MGIQLDEVSKVGLKIMVPQKTWDQMEVTTTSGQITLHNIAANKLTTESSSGQQHISGLQ
                     ISGSAAFQTTSGDIMAEQNEIASAKWETTSGKIQTAQLSGQSSEMQTTSGAIEYTQNEL
                     SPSVQLATSSGDIDAKLTGNTDSLQLQFESSSGTADIQIEGMLYKDKSEHSALGIKGEG
                     EAQHRIMLKTSSGDVQVGP"
     misc_feature    19764..19773
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    19793..19811
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.12"
                     /tool="antismash"
     misc_feature    19806..19819
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 20.64"
                     /tool="antismash"
     gene            20001..24479
                     /locus_tag="WH45_RS06825"
     CDS             20001..24479
                     /NRPS_PKS="Domain: Condensation_LCL (12-308). E-value:
                     9.7e-78. Score: 253.1. Matches aSDomain:
                     nrpspksdomains_WH45_RS06825_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (473-860). E-value:
                     5.3e-101. Score: 330.1. Matches aSDomain:
                     nrpspksdomains_WH45_RS06825_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (971-1034). E-value: 8.2e-13. Score:
                     40.4. Matches aSDomain: nrpspksdomains_WH45_RS06825_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1053-1349). E-value:
                     1.9e-54. Score: 176.5. Matches aSDomain:
                     nrpspksdomains_WH45_RS06825_Epimerization.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="WH45_RS06825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_046213627.1"
                     /sec_met_domain="Condensation (E-value: 1.7e-69, bitscore:
                     228.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-105, bitscore:
                     346.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.4e-10, bitscore:
                     33.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPRKVMAQGEGYALSAAQQRLWFLEKMAPHSAIYSIPQALSIHG
                     LLDVKRMKTAVRHMVERHPILRTVYQEDEQLNEVKQYIHPVPPDLVHFISMDTVIPDMR
                     EQQAKEMIAKLAAIPFNIDGGHLFTAHLFELKDTQHILFLNFHHSIIDGWSMGIFWKEL
                     LAHYQEQAEHLPELSIHYHDFAEWEKQHHSEAARQHLLYWTDYLQGTSMVRLDHDLSGT
                     IDPAMHQGGIGERSIPSSTSRRIIEYCQAQEVTPYLFFMTAFHLLLHKYTGEYDITTGT
                     PTSGRIHTETHNLIGFFVDMMAIRTQISEEQSFHDHLALVKQNVITCMDHQAVSFEQIV
                     QALQPERELAASPLFQLTFAYQQEGEMPAMEQLRLELFPVDNHTSKYDISVFVGLQNDQ
                     SFHIVCEYNSALYSADRIAQFLDHYEQLVVQIMADPGMPVSDLQIITLQQQSRLLNASS
                     YFPDAPHTFLSFKDRFEYYAQTTPDQTALVIDDREYTYAELNSKANRIAACLQKNNIRH
                     GEFVGVHFARSEKSIMAILGIMKAGAAYVPLDPAYPAERLIYMVDKAGLQYIVSDQTSQ
                     IFSDHISLLSMEQLLNETEYPAAPQPIHLLPEDTAYMIFTSGSTGAPKGVVIEHGSLSN
                     LIDAQQTVFDLHSDERVLQFASLSFDASVWEMVMALGHGSTLCMLPSDWKDMQQDMISL
                     FNRYKITIATFPSSFLVNMYPEELPSLRKVIVAGERCPVELAGRWAASKLFWNAYGPSE
                     TTVCATVFPYVAGSRVPIGYPLPNMQAYVLDEQKRPVPPGRSGELYIGGVGLAREYFAD
                     AAQTAAKFIHYPIGDNDQRLYRTGDIVKYDNQGVLEFIDRIDNQVKIRGYRVELGEIEH
                     QLSLVAGIRETVVICLERPNQTAELTAYIVCDVRGAVNRMDIMDSLNGRLPSYMIPANI
                     IELEHMPLTPNGKIDKKQLPLPVVMNEPVPGTDIQRDLTPAEQQLVAACEKVLKRTVRI
                     TDHFFESGGDSILVLKLINELKTLQWSLTPRSFYQYPVLEALAQKMQPLVEQCLEPETE
                     HEWFSLSPMQNWFFEQQFADAHHWNYSLLFKMPLHVEPEIIEQALYRLYRQHDAMRLQF
                     HYTAEGMRQSYRQHGAIPLHIVDQPAGCSISEFMQDTGAFHQQSLNLSDCLITAVLMRN
                     TEHKQQHLLLVVHHLLTDWVTGGIIAEDLNQFVEEALEDRENRLPSFSLSFKSWIDYLS
                     RHTLQQPVQQDLPYWQMTEHSQRLVPSVPLDRPDGINLKGTVKHVTIALTMEQTNDLIR
                     ISHYHLNSDVKTVLLSTVLYAIRAWSGMESIALDMASHGRHDLWEEVDITRTAGWLTSV
                     YPLVLQSKGQQTLTEYIYHVQQAIQLVPHEGITYGMLRYYAAEQRLDGYNSEIWFNYFG
                     HNHSLDNSPNTENKAPLLELCDDLLGSMNSYQQQRSHVFEILGMIREGQLHLGWQYSEQ
                     LHNRETIQQLADHVYTELAQLIAELKETYIK"
     aSDomain        20037..20924
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WH45_RS06825_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.70E-78"
                     /label="WH45_RS06825_Condensation_LCL.1"
                     /locus_tag="WH45_RS06825"
                     /protein_end="308"
                     /protein_start="12"
                     /score="253.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHSIIDG"
                     /tool="antismash"
                     /translation="YALSAAQQRLWFLEKMAPHSAIYSIPQALSIHGLLDVKRMKTAVR
                     HMVERHPILRTVYQEDEQLNEVKQYIHPVPPDLVHFISMDTVIPDMREQQAKEMIAKLA
                     AIPFNIDGGHLFTAHLFELKDTQHILFLNFHHSIIDGWSMGIFWKELLAHYQEQAEHLP
                     ELSIHYHDFAEWEKQHHSEAARQHLLYWTDYLQGTSMVRLDHDLSGTIDPAMHQGGIGE
                     RSIPSSTSRRIIEYCQAQEVTPYLFFMTAFHLLLHKYTGEYDITTGTPTSGRIHTETHN
                     LIGFFVDMMAIRTQI"
     aSModule        20037..24047
                     /complete
                     /domains="nrpspksdomains_WH45_RS06825_Condensation_LCL.1"
                     /domains="nrpspksdomains_WH45_RS06825_AMP-binding.1"
                     /domains="nrpspksdomains_WH45_RS06825_PCP.1"
                     /domains="nrpspksdomains_WH45_RS06825_Epimerization.1"
                     /locus_tags="WH45_RS06825"
                     /monomer_pairings="Phe -> D-Phe"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20046..20078
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0001"
                     /evalue="9.30E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="WH45_RS06825"
                     /protein_end="26"
                     /protein_start="15"
                     /score="8.8"
                     /tool="antismash"
                     /translation="SAAQQRLWFLE"
     CDS_motif       20097..20210
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0002"
                     /evalue="2.00E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="WH45_RS06825"
                     /protein_end="70"
                     /protein_start="32"
                     /score="39.5"
                     /tool="antismash"
                     /translation="AIYSIPQALSIHGLLDVKRMKTAVRHMVERHPILRTVY"
     CDS_motif       20436..20501
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0003"
                     /evalue="8.70E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="WH45_RS06825"
                     /protein_end="167"
                     /protein_start="145"
                     /score="31.1"
                     /tool="antismash"
                     /translation="FHHSIIDGWSMGIFWKELLAHY"
     CDS_motif       20826..20915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0004"
                     /evalue="1.30E-10"
                     /label="C5_LCL_267-296"
                     /locus_tag="WH45_RS06825"
                     /protein_end="305"
                     /protein_start="275"
                     /score="33.7"
                     /tool="antismash"
                     /translation="DITTGTPTSGRIHTETHNLIGFFVDMMAIR"
     CDS_motif       20964..21083
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0005"
                     /evalue="3.80E-14"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="WH45_RS06825"
                     /protein_end="361"
                     /protein_start="321"
                     /score="45.0"
                     /tool="antismash"
                     /translation="KQNVITCMDHQAVSFEQIVQALQPERELAASPLFQLTFAY"
     aSDomain        21420..22580
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WH45_RS06825_AMP-binding.1"
                     /evalue="5.30E-101"
                     /label="WH45_RS06825_AMP-binding.1"
                     /locus_tag="WH45_RS06825"
                     /protein_end="860"
                     /protein_start="473"
                     /score="330.1"
                     /specificity="substrate consensus: Phe"
                     /tool="antismash"
                     /translation="FEYYAQTTPDQTALVIDDREYTYAELNSKANRIAACLQKNNIRHG
                     EFVGVHFARSEKSIMAILGIMKAGAAYVPLDPAYPAERLIYMVDKAGLQYIVSDQTSQI
                     FSDHISLLSMEQLLNETEYPAAPQPIHLLPEDTAYMIFTSGSTGAPKGVVIEHGSLSNL
                     IDAQQTVFDLHSDERVLQFASLSFDASVWEMVMALGHGSTLCMLPSDWKDMQQDMISLF
                     NRYKITIATFPSSFLVNMYPEELPSLRKVIVAGERCPVELAGRWAASKLFWNAYGPSET
                     TVCATVFPYVAGSRVPIGYPLPNMQAYVLDEQKRPVPPGRSGELYIGGVGLAREYFADA
                     AQTAAKFIHYPIGDNDQRLYRTGDIVKYDNQGVLEFIDRIDNQVKIR"
     CDS_motif       21606..21647
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0006"
                     /evalue="3.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="WH45_RS06825"
                     /protein_end="549"
                     /protein_start="535"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LGIMKAGAAYVPLD"
     CDS_motif       21831..21890
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0007"
                     /evalue="5.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="WH45_RS06825"
                     /protein_end="630"
                     /protein_start="610"
                     /score="31.1"
                     /tool="antismash"
                     /translation="AYMIFTSGSTGAPKGVVIEH"
     CDS_motif       22371..22460
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0008"
                     /evalue="7.80E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="WH45_RS06825"
                     /protein_end="820"
                     /protein_start="790"
                     /score="37.4"
                     /tool="antismash"
                     /translation="PPGRSGELYIGGVGLAREYFADAAQTAAKF"
     CDS_motif       22545..22610
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0009"
                     /evalue="1.20E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="WH45_RS06825"
                     /protein_end="870"
                     /protein_start="848"
                     /score="33.4"
                     /tool="antismash"
                     /translation="FIDRIDNQVKIRGYRVELGEIE"
     aSDomain        22914..23102
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WH45_RS06825_PCP.1"
                     /evalue="8.20E-13"
                     /label="WH45_RS06825_PCP.1"
                     /locus_tag="WH45_RS06825"
                     /protein_end="1034"
                     /protein_start="971"
                     /score="40.4"
                     /tool="antismash"
                     /translation="EQQLVAACEKVLKRTVRITDHFFESGGDSILVLKLINELKTLQWS
                     LTPRSFYQYPVLEALAQK"
     CDS_motif       23160..23189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0010"
                     /evalue="7.20E-03"
                     /label="NRPS-E1"
                     /locus_tag="WH45_RS06825"
                     /protein_end="1063"
                     /protein_start="1053"
                     /score="9.6"
                     /tool="antismash"
                     /translation="LSPMQNWFFE"
     aSDomain        23160..24047
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WH45_RS06825_Epimerization.1"
                     /evalue="1.90E-54"
                     /label="WH45_RS06825_Epimerization.1"
                     /locus_tag="WH45_RS06825"
                     /protein_end="1349"
                     /protein_start="1053"
                     /score="176.5"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLLTDW"
                     /tool="antismash"
                     /translation="LSPMQNWFFEQQFADAHHWNYSLLFKMPLHVEPEIIEQALYRLYR
                     QHDAMRLQFHYTAEGMRQSYRQHGAIPLHIVDQPAGCSISEFMQDTGAFHQQSLNLSDC
                     LITAVLMRNTEHKQQHLLLVVHHLLTDWVTGGIIAEDLNQFVEEALEDRENRLPSFSLS
                     FKSWIDYLSRHTLQQPVQQDLPYWQMTEHSQRLVPSVPLDRPDGINLKGTVKHVTIALT
                     MEQTNDLIRISHYHLNSDVKTVLLSTVLYAIRAWSGMESIALDMASHGRHDLWEEVDIT
                     RTAGWLTSVYPLVLQ"
     CDS_motif       23250..23324
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0011"
                     /evalue="7.10E-02"
                     /label="C2_starter_024-063"
                     /locus_tag="WH45_RS06825"
                     /protein_end="1108"
                     /protein_start="1083"
                     /score="5.9"
                     /tool="antismash"
                     /translation="VEPEIIEQALYRLYRQHDAMRLQFH"
     CDS_motif       23520..23585
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0012"
                     /evalue="5.60E-04"
                     /label="NRPS-E2"
                     /locus_tag="WH45_RS06825"
                     /protein_end="1195"
                     /protein_start="1173"
                     /score="12.7"
                     /tool="antismash"
                     /translation="LLLVVHHLLTDWVTGGIIAEDL"
     CDS_motif       23994..24044
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0013"
                     /evalue="3.60E-06"
                     /label="NRPS-E5"
                     /locus_tag="WH45_RS06825"
                     /protein_end="1348"
                     /protein_start="1331"
                     /score="19.3"
                     /tool="antismash"
                     /translation="DITRTAGWLTSVYPLVL"
     CDS_motif       24108..24149
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06825_0014"
                     /evalue="1.00E-03"
                     /label="NRPS-E6"
                     /locus_tag="WH45_RS06825"
                     /protein_end="1383"
                     /protein_start="1369"
                     /score="11.7"
                     /tool="antismash"
                     /translation="VPHEGITYGMLRYY"
     gene            24476..>26706
                     /locus_tag="WH45_RS06830"
     CDS             24476..>26706
                     /NRPS_PKS="Domain: AMP-binding (17-416). E-value: 3.6e-105.
                     Score: 343.8. Matches aSDomain:
                     nrpspksdomains_WH45_RS06830_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (524-593). E-value: 2.7e-26. Score:
                     83.6. Matches aSDomain: nrpspksdomains_WH45_RS06830_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="WH45_RS06830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_152663494.1"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-114, bitscore:
                     374.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.4e-16, bitscore:
                     53.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.6e-32, bitscore:
                     106.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMHTTNVITTFKTVPEIFRESLREYPHCVAIENDCSSVTYAELDQ
                     YSDRIAAGLMERGVKQGDMVGTLMERSPELFASWLGILKVGATYVPVDPANPAERIKYI
                     VEDSGMAYLITDQGNRQAPIASLNLCASLHVEELLSERSLISFHQNTYNSDNIAYMIYT
                     SGSTGRPKGVRITDRGIVSLVQNSTYAQLDHTDIIAQASNASFDAITFEVWGALLTGAR
                     VVIAPRETILSVERFSAWLVDKNITILFITVAWFNHIARHEPAAFASLKTVLFGGEACN
                     VRWINEVLRAGKPLHLSNIYGPTECTTFSLSYEITEKELDEQQKVPIGKPINHTLAYIL
                     DERQQLVPYGVTGELYIGGEGLAAGYWNRPELTAERFVHLPQLADGPLYRTGDLVQRRA
                     DGQIDFIGRTDDQIKLRGHRIELGEIEEALRSCPGICEAVAALTTVSGQEEPVLAVYYA
                     TEQELEAGQLRDQLQQRLPAYMVPAAWREVESFALTVNGKIDRRQLPPIQEQDLRQQAY
                     QQPDRPGEAEIAAIWADLLNRQQIGAQDHFFAIGGHSLLAAQVVSRMEEQLQRQVTLRA
                     LFDYPVLRELAAYVQQQPVSGPASVIPAYVSEDGRYPLSPAQQRLWLVQQLEPDSQAYH
                     IPFAFHLYGILDADRLEQAIHEVVERHDSLRTQFGEESGEPYQQVTGNLPVLERSSLHV
                     PVGEQEQHLQEVLQREAWETLSLTAAPPLRLRLIELEAGHHVLSWVIHH"
     aSDomain        24527..25723
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WH45_RS06830_AMP-binding.1"
                     /evalue="3.60E-105"
                     /label="WH45_RS06830_AMP-binding.1"
                     /locus_tag="WH45_RS06830"
                     /protein_end="416"
                     /protein_start="17"
                     /score="343.8"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FRESLREYPHCVAIENDCSSVTYAELDQYSDRIAAGLMERGVKQG
                     DMVGTLMERSPELFASWLGILKVGATYVPVDPANPAERIKYIVEDSGMAYLITDQGNRQ
                     APIASLNLCASLHVEELLSERSLISFHQNTYNSDNIAYMIYTSGSTGRPKGVRITDRGI
                     VSLVQNSTYAQLDHTDIIAQASNASFDAITFEVWGALLTGARVVIAPRETILSVERFSA
                     WLVDKNITILFITVAWFNHIARHEPAAFASLKTVLFGGEACNVRWINEVLRAGKPLHLS
                     NIYGPTECTTFSLSYEITEKELDEQQKVPIGKPINHTLAYILDERQQLVPYGVTGELYI
                     GGEGLAAGYWNRPELTAERFVHLPQLADGPLYRTGDLVQRRADGQIDFIGRTDDQIKLR
                     "
     aSModule        24527..26254
                     /complete
                     /domains="nrpspksdomains_WH45_RS06830_AMP-binding.1"
                     /domains="nrpspksdomains_WH45_RS06830_PCP.1"
                     /locus_tags="WH45_RS06830"
                     /monomer_pairings="Ile -> Ile"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       24713..24754
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06830_0001"
                     /evalue="1.40E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="WH45_RS06830"
                     /protein_end="93"
                     /protein_start="79"
                     /score="15.2"
                     /tool="antismash"
                     /translation="LGILKVGATYVPVD"
     CDS_motif       24947..25003
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06830_0002"
                     /evalue="6.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="WH45_RS06830"
                     /protein_end="176"
                     /protein_start="157"
                     /score="28.0"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGRPKGVRIT"
     CDS_motif       25517..25606
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06830_0003"
                     /evalue="1.20E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="WH45_RS06830"
                     /protein_end="377"
                     /protein_start="347"
                     /score="55.9"
                     /tool="antismash"
                     /translation="PYGVTGELYIGGEGLAAGYWNRPELTAERF"
     CDS_motif       25688..25753
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06830_0004"
                     /evalue="4.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="WH45_RS06830"
                     /protein_end="426"
                     /protein_start="404"
                     /score="37.9"
                     /tool="antismash"
                     /translation="FIGRTDDQIKLRGHRIELGEIE"
     CDS_motif       25904..25978
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06830_0005"
                     /evalue="5.80E+00"
                     /label="C2_LCL_024-062"
                     /locus_tag="WH45_RS06830"
                     /protein_end="501"
                     /protein_start="476"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="PAYMVPAAWREVESFALTVNGKIDR"
     aSDomain        26048..26254
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WH45_RS06830_PCP.1"
                     /evalue="2.70E-26"
                     /label="WH45_RS06830_PCP.1"
                     /locus_tag="WH45_RS06830"
                     /protein_end="593"
                     /protein_start="524"
                     /score="83.6"
                     /tool="antismash"
                     /translation="EAEIAAIWADLLNRQQIGAQDHFFAIGGHSLLAAQVVSRMEEQLQ
                     RQVTLRALFDYPVLRELAAYVQQQ"
     CDS_motif       26309..26350
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06830_0006"
                     /evalue="7.30E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="WH45_RS06830"
                     /protein_end="625"
                     /protein_start="611"
                     /score="9.4"
                     /tool="antismash"
                     /translation="YPLSPAQQRLWLVQ"
     CDS_motif       26372..26482
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_WH45_RS06830_0007"
                     /evalue="4.30E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="WH45_RS06830"
                     /protein_end="669"
                     /protein_start="632"
                     /score="54.5"
                     /tool="antismash"
                     /translation="AYHIPFAFHLYGILDADRLEQAIHEVVERHDSLRTQF"
ORIGIN
        1 tctgctggcc gacgagatca accgggccac gaccaagacg cagtcggcac tactggaagt
       61 aatggaagag cgcaatgtga cggtcgatgg cgagactcat ccgctgccgc atccgttcat
      121 gctgtgtgcg acccagaacc cgattgattt tgaaggaacc tatatgctgc cggaagcgca
      181 gctggaccgg ttcatgatga agattacgat cggttatccg gatgagcaga ccgagaaaaa
      241 tctgctgctt cagcagggag tggccggaca gccggttgac cgtctggagc ctgtcaccga
      301 tatgcagagc attgcggata tccagcagga gattcgcggg gtgcatatgg atgaatccgt
      361 cagcgactat ctggtacgga ttatccgggc gacgcgcgaa caccgttcgg tactgctcgg
      421 tgcaagtcca cgggcgacgc tgtcctttat gatggcagtc aaagcgtacg cctttattca
      481 tgagcgcgat tttgtgctgc cggatgatgt gaagcgtctg gcgccttata ttatcggtca
      541 ccgtatactt gcccgtccgg aagcacggat ggagcgcatg agcgcagacc ggattatgca
      601 tcagattctg gagcagatcc cggctcctgt atcggtgggg ccataatacc atgagagcac
      661 tattttcata tttgcggctg aatctgcagc gccagcatca gccatccaaa ttatggctcg
      721 tcgtgctggt atggatcggc tgcctgttgt atatgctttt tcagggcggc aaaacgtcgg
      781 tcatgttgtt ctccatggtc acactgctgt ccctttatct gattggcgga ggctttcgcg
      841 gcgtgggacg tgcgcggggc agccgtcatt tgtctatcgg cggcgatcat agcgagatta
      901 tccatgcggg cgatcaggtg caggtgcgcc tgagtgtgac cattccgggc ttcctgccgc
      961 tgccgtatgt gattgtccgt gagacgctga agcgtcataa cggcgaatca tggtcatttg
     1021 aggagagtct gattccgagc atgagaggca agggagagct gctgttccag acgccgccgc
     1081 tggagcgcgg gcgttatcgt ttctatggaa cagagtgtat cagtgaagat attttcggac
     1141 tgctggagaa taagggcaag ttcaacgctc ccggtgaatt tctggtgctg ccgcggacag
     1201 cttttgttcc ttactgggaa atgggttctc gtcactcgcg tcttggcgga cagcagactt
     1261 cgcagctgat gtcccgtccc gagactaacc agatcaacgg agtgcgtgac tatgtgtacg
     1321 gtgaccgtat ttcccggatt cactggaacg cgaccgcacg taccgggatc tggaagtcca
     1381 aggaatttga acatgaagca ctgcccaaga ccgtcattgt gctggatggg atggccgatc
     1441 attatgaatc gggtacccag tttgagctgg cggtatcggt cgcttcgtcc atgctggaat
     1501 acggcatgcg cgagcgaatg ggtatgggtt tatttacaat tggtgaagac aattattcat
     1561 tcctgccgac ggatcaagcg gcagactggc accggatgca ggtgcatctg gtagatatta
     1621 tggcggatgg ccggggcgag ctgctggata agctggagcg ggatgcacgt ctgttccctg
     1681 caggttcgct gtttgtcctg atcagtccgc tgcgcggtga caaagcctgg gagattttcc
     1741 agtttgcacg aatgcgtcag atgaatccgg tacagatccg gatcgaaggc aaggagcagg
     1801 aatccgccgg acaggaacct gccgttgatc atatccgggg tgtggccagc tatgcgctga
     1861 attccctgga tcagctgccg gtggttttag gagggagagc cctatgataa agtggtggag
     1921 cggtattcgc agctcctggt attactcgct gtgcctgtta tgggtgatga ttattgccta
     1981 tcaatggatt caatatgcgg cagacatctg gtataccgag acgacattac tcgtactcgg
     2041 aacgatggct gctgttgcag ttatagatat tgtactgccg gtcaacgcct ggtatcggct
     2101 gctgatcaag ctggtggcgg ttattgtagt ggtatattac gcactagatt attatggtat
     2161 atatcactgg cagcccggcg aatcgccgat ggcgaatctg gaactgttca tagagacgct
     2221 tcgttcctat gtgtggttcg taatctctgc ctgggtgctg ctggaggtct ccgcgcgcat
     2281 cggtacgtcg cgccgggcga tcatcatgtt tgtcggtacg aacattatcg cgctggccgt
     2341 tcttgattcc tttacggctg cgacattatg gcaggaagtt gcctgggtgg tatttgccgg
     2401 aatgggctgg ctcgtgagca atcatttccg ttattttcag gagagattcc ccaaaggctg
     2461 gaagcatctg cgcaaatatc cgctcaaaat catgtttaat atcgccgtaa ttttctcgat
     2521 tgtactgcta gcggggatca atatgccgga gattcagccg acactgaaag atccgtatac
     2581 cgcctggaaa aactggcgcg gcgagtcggt tattaccatt aatggctcga gtccgctgga
     2641 tggacagggt gcttcctccg gctacagccg ggaagactcc aatctgggcg gcggcttcaa
     2701 ctttgactac acgccggtaa tgacggtgag cactaccagc cgtagttact ggcgcggcga
     2761 gacccgtctg gcctattcgg gtacgggctg gattgatcgt tccggcaatg gctggcggga
     2821 gctggatccg gtaaaagccg gagacgagct gtcgctggat gagagttcgg atgaagacaa
     2881 gcgcagcgtc aagcagcagg taaaaatgct gtcggacaac aatacgacct atccggtgct
     2941 gttcggtgcg tatacgattg ctcgcatcga agacgtcaat ggcggagatg atacgagtca
     3001 actggactgg cgcagcaaca acggtgaggt gcactggagc cagacccggc agaatcggca
     3061 gtacccggaa tcctactcgc tcgtatcgag agtacctgtc gtaccggtag ccgatctgga
     3121 aaaggaaacc tacaaccagc tgtatgccgg caaatcgctg gagccgtatc tgcaggtgcc
     3181 gtcggatttc cccaaacggg tcaaagatct ggcaaaggaa gtaactgctt cggcagagac
     3241 gccttaccgc aaaatcgaac tgctgcagca gtatttgcaa aataattatg cctatacgaa
     3301 caacccggat ctttcccgcc aaaaaagcag cgactttgtc gacagctttt tgtttgagat
     3361 caaggaaggg tactgcgatt attattccac tgccatggtc atgatggccc gctcgctgga
     3421 tattccggca cgctgggtca aaggttatgc gcccggtcag gcgtccggct atgtcaccaa
     3481 tgactatttc cctgacggtg caaccgaata tacggtgacc aatgcggatg cccattcctg
     3541 ggcagagatt tattttgccg ggtatggatg gattccggtg gaagcaacgc cgggctttga
     3601 tatgccgctg ttgaccgaga gtgtacagac acctgcggcg acgccggata caccggagca
     3661 ggaagaaact gcaccgcagc cggaagcgga agataccaag gctcctgtgc aggcttcgga
     3721 tcgtgccgta tcgccagctg tcgtctggac agcggcagtg ctggtcgctg catggaccgg
     3781 attcatgctg tatcgttacc gtcgccagct caaagcagcc tatacgcgta ttcgctacgg
     3841 agaaccgatg acaccacaac agaaaatcat ggcggaatcc aaacgctggc tgagctggat
     3901 gaagcggcat ggcatggatc gtcaatctca tgagaccctg cgggaatcgg taagccgctg
     3961 gcgggagatg cgtcccgaac tgagcggagt gctggacccg ctgctggccc tgtttgaacg
     4021 ggccaagtac agtcccgagg tggttaccga ggatgaatgg gtatcgatga agcagcattt
     4081 gcaggattta cgaaagttat ggcgcaaatc tgccgcaaag tagtataatg gataaagtgc
     4141 gtatcggccg gtctcgatgg agcaccggtc gatatcgtgt gagccagagt atcccgatca
     4201 aaaaaatacc atgaagttca aaataacgcc gcatagcggc gtttcttttt gtcagagtgg
     4261 ttaaatttat gatatagttt gtcgtatgaa atcgaggtga ataaagcttg tttgaattac
     4321 tcattcctaa attacgtgta aatacagtat ttgatattga tctggaaaag ctgtacgccc
     4381 agggctatcg ggggatcatt acggaccttg acaataccct ggtcggtgcc aaatcaccta
     4441 cggctacgcc tgaactgata gaatggttcg ccaaagtaaa aaagtacgga tttgaactga
     4501 ttattgtatc caataacaaa atggacaggg tctccctgtt tgccactccg ctggatatta
     4561 agttcgtgca tgcagcacgt aagccgtcca atgccccttt ccggaaggcg atgaaattga
     4621 tgaactgccg cgatgatcag acgatcgttg tgggggatca gctgttgacg gacgtgtatg
     4681 gagggaatcg tctgggctta ttcacagttc tggtgctgcc aatcgctctc aatgaagagg
     4741 gctggcgaac ccggtttaat cgtcaggtgg aacggctggc aagaacaaga cttcgcaaaa
     4801 aaggcttatg ggctgaggag gaacgcaata aatgacagaa cttagcgggt taaccgctgg
     4861 aaccaaatgc agcggctgcg gtatcgtgct gcagaatgaa tccccggatc atccgggcta
     4921 tataccggca caggcgcttg aacggacacc actgctgtgt cagcgctgtt tccgcatacg
     4981 taactacaat gaatcgtcga cagtaacggt agatcagagt gaattcttac gtctgcttgg
     5041 tcaagtaggg gaacaggatg cactggtcat ccatattgtc gacctgttcg attttcacgg
     5101 tagtgtgatt tccggactgc agcgttttgt aggcaataat cctgtagtac tggcggtcaa
     5161 caagatcgat ctgctgccca aagtaaccaa ctggaacaag cttcgcaact gggtccagaa
     5221 ggaagccaag gaacttggac tcaaagtcga agatatcgta ctgtgcagtg ccaagcagaa
     5281 taccgggttt gatcgtctat tggatattgt cggctcgatg cgcggtgacc gcgacgtcta
     5341 tgtggtcggc gcgaccaatg tcggcaaatc gacgctcatt aaccgtctga tctccgatta
     5401 cagcgatctg gaagaagagt tgaccacttc ccgttatccg ggtacgacac tggatacggt
     5461 gaatattccg ctggatgacg gtcattatat tatcgataca ccgggaattg tatacgaatc
     5521 ccgttatacc gaattggtga acaagcagga tctggctgcg attatgccgg acaaaccact
     5581 caagccgctt gtgtaccagt taaatcaagg acaatctctg ttcttcggtg cgatggtacg
     5641 gtttgactat attcagggag gacgtcagtc ttttaccctc tacttgaata atcgcctcaa
     5701 aatccaccgc accaagctgg agcgcgcaga tgaactgtat gcgaaccatg caggtgagat
     5761 gctggctccg ccggtcaaag cggatctgga caaactgccg gcgtggacac gtcacgagct
     5821 acgtattccc aaaggcaaac cgacggatat cttcatctcc ggactgggct ggatcaaagc
     5881 taacagtacg gacggcgcac tcgttgccgt acatctgcca aaaggcgtca aagtgatgat
     5941 gcgtccgtcg ctgatctgat catttcgtaa gtaatgagga ggatgagaat aatgactgac
     6001 cgtaatcagg ccaacaagca ggctgctctg ctgctcggag tcatgggtga tccgatcgcc
     6061 cactccatgt ccccggtaat gcataatatc gcattggaag cggccggact gccgggaatg
     6121 tatgtgccgc tgcacgtcaa gccggatcat ctggccgagg cggtcacagg cgcccgtgcc
     6181 cttgggttca caggcttcaa cgtcaccatc ccgcataagg tggagattat gaagctactg
     6241 gacgaactgg acgaatccgc agtcagctgc ggagcggtga atacggtagt gatccgtgat
     6301 ggacggatga aaggatataa taccgatggc atcggctatg tgcgttcact gcgtgaggaa
     6361 gccggggaac tggccgacaa gcgggtgacc gtactgggcg ccggaggagc agcaagaggg
     6421 attgtctatg cgctgctcaa ggaaaatgtc gccggtatta cgctcatcaa ccgtacggtg
     6481 gacaaagcag cacaactgat tcgggaactg aacgcttccg atgcacagat gcagacagcg
     6541 acctatgaag agctggcaga gtatctgccg cagaccgata tactcattaa tacgacctcg
     6601 atcggtatgc atccgaatat ggacgagacg cctgtagccg cggagctgat tccggaaggc
     6661 attattgtca gtgatctcat ttacaatccg atggagacac gcctgctgcg tgaagcacgt
     6721 gcccggggct gccggacggt aggcggactg ggtatgttca tttatcaggg cgcgtatgcg
     6781 tatgaatact ggacaggaca ggaagcgccg gtgtcgctga tgcacagcgc ggtactggaa
     6841 gcactgaacc atgcaaatca ttaattataa ttaaggggat atacaatgct aactggaaaa
     6901 caaaaacgtt atttgcgcag tcaggcgcat catctggacc cgattttcca aatcggtaaa
     6961 gccggtatga atgaaggtat cgtccgtcac gttctggatg cgatcgagac acgtgaactg
     7021 atgaaggtat ccgtactgaa caactgcctg gaagagccaa aagatctggc cgagcagctg
     7081 gctgaaggta caggagccga gctggtacag gttatcggac gcacaatcat tctgtacaaa
     7141 gagtccaaag atcacaagca gatcgaattg cctagaggtt aagtcaaagt caggcagccg
     7201 attttgctgg aataaaaaat gattcggtgg tgggttcatg aaagtcggta ttatgggagg
     7261 tacatttgat cctgtgcata tcgggcatat gctcgccgca gaggccgcgc ttgaaggctg
     7321 cgaactggat gaagtctggt tcatgccgtc acatattccg ccgcataagc atgcggccgg
     7381 tgtaagcgga gagcagcgtc tggagatggt ggagcatgcc attggcacca atccggcatt
     7441 ccgtacgctc gatatcgagc tggtccgcgg cggtgtatcc tatacgattg agacaatccg
     7501 tgcgctgcag gagcggtatg atcagcatga attctacttt attatcggag cggacatggt
     7561 aaactcattg accgagtggc atggcatcga agagctggcc cggcgtctga cctttgttgg
     7621 tgtagggcgt ccgggctcgg tcattcatac ggagaccatg cctgcctatc tgcagccgag
     7681 agtggtgctg gtcaatatgc cgcaggtgga tatttcttct acagacatcc gtgaacgtct
     7741 cgctgccggc aaaaccgtcc gttacatggt gcacgatcat gtgtatgaat atatcaagag
     7801 gagtggactc tatgaatctg acacgcgctg aactcattca atccgtctcc tctcaaatgc
     7861 cggaaaagcg ctggcgccat accgagggtg tcatgcagtc tgctgtcgta ctcgcccggc
     7921 gttatggggc agaccccgac aaggcggatc ttgccgccat tttacacgat gtggccaaat
     7981 actggccgag tgaccgtcag gagcagctgc tccgcgacaa ggcgctcaat gatgaactgc
     8041 tgttatatga taagccgctg tggcatgcgg agatcggcgc ttatgtcgcc gagaccgaat
     8101 acggtattga agacacggag attctcaatg ccatccgcta tcatacctcc ggccgcgtag
     8161 gcatgacgac tttggaaaag gtcatctgtc tcgcggatta tattgaacct ggccgtgatt
     8221 ttccgggagt cgaccatatt cgccgtctgg cggagaccag tctggaagcc ggactggtcg
     8281 caggatttga ttccacgatt aatctgctgc tggcgcggcg tcaggtgatt tacccgttaa
     8341 cggtattgtc cagaaatgat ctggtcaaac aacttgaatt ggagggagaa ctttaaatgg
     8401 cattaaatcc ggaacaattg ctgcaaatga caattgacgc agccgaaagt ataaaagctc
     8461 acgacctggt ggcactggac ctgagaggaa tctcgctggt agccgactat tttgtaatct
     8521 gtcatggtaa ctcggataca caggtacaat cgatcgcatc cgaggtgcgc aagcgcgccc
     8581 atgatgccaa tgtagtaatc cgtggtatcg aaggcgttaa cgcggcacgc tgggtactga
     8641 tcgacctggg tgacgtcgtg gtacacattt tccatcgcga cgagcgcgaa tattacaata
     8701 tcgagcgtct gtggtccgac gccaaagtgg tggagaaagt atgagcctgg aagcaggaac
     8761 gattgtcacg cttcccatcg ggcgtgaagt atccccttat ggctttttcc tgactgatgg
     8821 tgagcaggaa gtactgatgc attacagcga actgatcggc aaagtaaaag tcggcgaccg
     8881 ggtggaagca tttattttcc atgataccga agatcgtctg gccgctacga tgaaaaagcc
     8941 gctgctgact ctgggagaac tgggcaagct gaagatcgcc gatctgcatc cgcgtctggg
     9001 tgcttttctg gaaatggggc ttggacgcca gctgctgctg ccgatgagcg aactgccgga
     9061 gaagccggaa ctgcgtccgc agatcggtga cgaggtgtat gtggtgatgc agcatgaccg
     9121 tcagggtcgt ctgctcgccc gtctcgccgg tgaagaggaa ttcaatccgc ttgtattcca
     9181 tgcaccaacc agctggatga atgaatgggt ggaagcgctg gtgtacaagc cgctccagat
     9241 gggtacattt gtactcgtgg atggcggcgt actcggcttc ggcgtactcg gtctgattca
     9301 tcagaacgaa cgcagccgga tgctgcgcct gggggaacgg gtcaaagtac gcgtgaccca
     9361 ggtacgcgag gaagacggac gtgtgaatct gtccatgatc cagcgcaagg aaatcggacg
     9421 tgatgaagac tcccagcgtc tgctgtcctt tatgctggat cgcccggaca aggcaatgcc
     9481 ttattcggac cggactccac cggatgtcat caagcagcgc tttggcatca gcaaagcagc
     9541 tttcaagcgc gcactcggca agctgatgaa agaaggcgtt gtcgtacagg atcagaactg
     9601 gacacgtatc gtggacaagg atgctcctgc cgctgaaggc acacaggaat cccagcaata
     9661 aagggaacga ttgattttca attacagacg gaaaggttag gactgcatcc cgcagtccgg
     9721 acctttctgt ttttgcatca gccatgatca ccggcatgca aaaacaggga aggacggtta
     9781 aagcagtgcc ataccgcaag tttgcctatg tatatgatga gttgatggaa gacatgcctt
     9841 atccggactg gctgcgtttt gtacgtgaag cctgggatcg atatggaatg ccgcgtacgg
     9901 tagccgagct gggctgcggt accggcagca ttaccattcc gctggtgaac tccggcttcc
     9961 gaatgactgg aattgatctg tcgtcggata tgctctcggt cgcccgtgac aaaatggaat
    10021 caacgtcgca gggacaccgg ctgttccagg atggcagtgt ccagtggatc tgccagaaca
    10081 tgaccagctg gcagctgcct gagccggtag acagcgtcat ttccttttgc gattgtctga
    10141 attacctgac cgaaccggaa gatattgtgc atacgtttca gtccacttat gccggtctga
    10201 agccgggtgg tacgtttatt tttgatgtgc atcatccgag cacgctgcgc cgatatgatg
    10261 aagagcagcc ctttatgctg gatgaccggt cgatctccta tctgtggacc tgtgagtatg
    10321 atacggcccg cacggagatt gagcatcatc tgacgatttt tgcccgggta aatgaagaca
    10381 gccagtcgct gtatgaacgc tttgaggaaa tacatgtcca gcgtgcctat gaacaggact
    10441 ggctgcgtac cgagctgtac aaagccggct tccgtgatgt gaaatgttat gccgactttg
    10501 aatggatcga agcaagcgat gatgccgccc gtttattttt tatcgccgtc aaataagacg
    10561 ggcatgacaa aaaaacggaa taatatgtaa agctcctgtc tcaggagctt tttacttgtg
    10621 cgtacatata gacaatacaa tttaaatagt cggtaaaata aaaagaatga tgatatttgt
    10681 cgaagcatga attgtgtata ataaatacaa ccgataaaat gaacccgata atacaaacaa
    10741 gaaggcaatt caatgctacg atgatgggga cgatatatgc agacgattat tcagacattg
    10801 ttcaacaatc ttaccttttt gacgactgtc ctttttttcg gaaatctttt tctgaaattt
    10861 atggatcaaa aattacagag agtaaattgg atgattccag tgcttgccgg agtatttgca
    10921 ggcttgcttg gcatttgcat gatgagcttt ttctcaatcc gtttctctac cggagataat
    10981 acggttatgg tggattttcg ccagctggct attatgattt ccttttatta tggcggagcc
    11041 tggagtgggc tgatctcggc gattatgata ggcgtgtatc gtctgttcag cggagagccg
    11101 ctgcaattca gttcatgggt cgggtttggc aatgcgatgt ttacgtatgt cgttacctca
    11161 ctgtgcatgc gcggcccacg ggagacctcg ctgaaaatct ggttcagagc gattatcgct
    11221 actttgctgg tttatatcgt ggctgtcacc attttgcagg cgattacaca tattgagctg
    11281 aatctgtttt ttggattgtt atatatttgt gccgggctgt tcgcctatta tatcatccgc
    11341 tatatccagc gggccgatga tacgctcact atgaccaggg aagcggccaa tcatgatttt
    11401 ctgacccagt tatacaatcc gcgtgcgttt gaccggctgt tccgacagac gattgttgat
    11461 gccagggagc atcagcgatc atttgccctg ctggtcgtag acatcgattt tttcaaaaaa
    11521 attaacgata gttacgggca tcttaacggg gatacggtat tggtacaggt agccgaagtg
    11581 ctgggccgga cgattcgacc gggagactac tgcgcccgca aaggtggaga agaatttgcg
    11641 gttattctga acgagtgtga tgagcgacag gcagtagagc tggcagagga gatccggacc
    11701 gcaatggaac agcatacctt tgtgctggaa gagggacaga gcatccaatt gaccgtttca
    11761 atcggagtaa gctgttatcc attgaccgcg ccggagcagc tctttcccga agcggaccgt
    11821 gcactttacc aggccaagga aaatggacgc aatcgggtag cgctggctga ctgtacgccg
    11881 gcagagtaaa agctgattta agacaaacaa cccaaaaggc tgtctctctt gtgagtacca
    11941 ggagcagaca gccttttggg tcattttttg gccatattat aagttgaata atcttcttgt
    12001 cagccgatta gtttaaccga acgattcggc aggaatgaat gcctgctttt tttgcagatc
    12061 gactctaccc gagaagaagg tggcaccgcc gcccatatca gacaggcggt ccggagtcag
    12121 tgcattcacc agatgagacg gctgatgatc cggggtgtcg gcccatagtc cctggctgac
    12181 caccacgccg ggcagcaccg tctcgccgac agcggcgatc agttcacagg agccgtaccg
    12241 attggagacg atgacggtat cgccatcaac gatgccttcc cgctcggcat cagccgtgtt
    12301 cataaacagc cgcggcagct tttccatacc ggcatgcttg gcattattgg agaaggtcga
    12361 attcaggaaa ttatgtgtcg gacccggtat gaaaatatag ctgtgactgt cctgttcctg
    12421 cagcggaata taggtcggca gcggcggcag accatgctgc agcatggtgc tggagtatag
    12481 ttccacctta ccgcttggcg tatccagccg ctccgggtaa atggtggcac ggttcgcctt
    12541 gagatactga tgatccagca gtccctcata atcaattccc tgcaaatgcg gattgcccgg
    12601 atgagccagc gcctggcgga tcatctgctc atcactgtcc tgcagcgctt gctcttcaaa
    12661 gcccatcgca gccgccagca gacgaaacac ttcggtattg gatttacttt gtccataatt
    12721 ctcgatcacc ggctgaccga tctgtatata atgatgccag taggacgtat agaaatccag
    12781 attctcaaag gctgaagtgg caggcagtac aatatccgca tatgccgctg tctccgtcaa
    12841 aaacagatca tgcaccactg taaacagatc ttcccgctcc agtccctcac gcacctgtgc
    12901 agcacgaggc gctacgacag ccggattgca gctgtagaca tacagggaat ataccggcgg
    12961 ctcggcagcg gtgagcgccc ttcccagctg gttcatgtta aaagaacggg tattgcggtt
    13021 gtgcagcaga tcaggacgct gcagagcggc tgcattatga gccagataag cagaattgga
    13081 acggatcgct ccgccaccgc gcaccagcca ctggccggtt aatacggata ggcaggtaat
    13141 cgcacgagta ttcatgccgc cgttatcatg atgctgcagc ccattgccga tgcggatcat
    13201 ggacggggcc gtctcgctat acatacgggc caatttgtaa atgtcatcca caggaacgcc
    13261 tgtgatgccg gatacggtta ccggatcata ggacttcaca tgttcacgca gctgttcatg
    13321 cccgattgta tattcatgca gaaaatgctc atctacccgg ttctcggcga acagtacatg
    13381 catcagccca agcgccagtg cagtatccgt gccggggagg atcggaatga accagtccgc
    13441 catccggccg gtctgattgc ggtgcacgtc gatgacgacg attttggcgc cctgcttgcg
    13501 tgcctgctga gccagggtaa tctggtgcat attggtactg accgcattga ttccccacag
    13561 gataaacaat cgtgtatgca ccgtgtcttc cgggtcggtt cctatgctgc cgcccatcgt
    13621 atacttgaat ccggctcctc cggctgccgt acaaattgta cgctccagct gactggcacc
    13681 caggcgatgg aaaaagcgcc gatccatgcc ttccgcattg atattgccca tattgccata
    13741 gaagctgtac ggcaggatgg tttcgggacc atgctcttca atcaggcctt tccagcggga
    13801 agtgatcatc tcgatcgcct ctgtccatgt aatcggctcg aactggcggc tgcctttggg
    13861 tcctatccgt ttaagcggct gggtgagacg ttgatcatca tagatacgct cggccatatg
    13921 ccgtactttg ttgcatatat tgccacgggt aaccggatgt tccgggtcgc cggcgatttt
    13981 ggtgattttg ccgttttctt tatgaatgag cagtccgcac tgatccgggc agtccagtga
    14041 gcagaccgtt ttgaagacgc catccggctg ttgcgtataa gcagacatga atcactgctc
    14101 ctttcgggtg agtatttctt ttaaatttta ttccaaagag attctcttta atgtcgactt
    14161 tgttactggg tttaattaga atcaagaaga attattgtcg aatcgacaaa tttagtcaag
    14221 cttacattgc tacatatcat agcgtgttcc ttattattgc acaaccttac agctacatat
    14281 tcattatatt ttctgtgcag agagcggaaa gggctgccct tgcgataact cggcaatttc
    14341 caagctgtac agagcctctt tccgtacctg gggaaagagg ctcttttggt ttacattatc
    14401 tatactcttt gctttaaagc taactactaa ggccgtcagc agctgaagga tgggtgtaca
    14461 gtaagaagat gtatcggtgc ggttgtaaaa gcaatggaat ggtagtattt taatgtaaga
    14521 tattttgctg aaccccgaat cactttttta ttgaagcaag agataatcct tttctgcatt
    14581 gaccgaaata aaataaatac ataataaggc agcacgatcc agttgatata cagcgctgcc
    14641 caactcaact tctatcctgg cgatgtatat gctgaagata ggagtttttt tgcgagatgg
    14701 ggttctgttt acaccgctaa aagtagtatg tgcatctata ctatacacct atacttttat
    14761 aagtttaagt tacttttata agtattattt gctgaacaac aatgcataaa tctcctatct
    14821 gtatgaaaaa atgctacgat tcactcgatt aaccaaagta ataatattcc tttcaatcca
    14881 cataattatc aataaaatat aaaattgtaa aatcaataca atctaaggta gaataaaatt
    14941 gacaatgaac gtaaggggga acagcaagtg aataatcgaa ttttattgat tgaagacgat
    15001 gtatctatca gtgaattgat ccagactcaa tttgccaaag aaggttttga tattagctgt
    15061 gcttatgacg gggaacaggc acttcaggcc ttctcggaag atatatttga tatcattttg
    15121 ctggatttga tgcttcccaa attggatggg atagaaattc tgaaaattat tcggtcacag
    15181 agcatggtac cgattctgat tatgtctgca aaagacgggg atcttgataa agcccttgga
    15241 ctcggttttg gagccgatga ttacatatcc aagccatttt ccatgattga attaaccgcc
    15301 cgggtaaaag ccaatatccg gcgtgcactg caatattcca atcctgttat tacaacagtg
    15361 accaaagaaa agatccatgt gggtgaattg gatctggata cggataattt tgccgtgtac
    15421 aaaagcgagg atgaaattaa actcactgcc aaagaatttc aaatcctgaa attattcatg
    15481 actaacccca aaaaagtatt taccaaggcc caactgtata atctggtctg gggtgaagat
    15541 tactacggtg acaacaatgt aattaatgta catatgagaa gactgcgtga aaagattgaa
    15601 gatgatcctt ctactccccg ctatatcaaa acattatggg gcatcggtta taagctggga
    15661 gaattttaaa tggatattat actggggctt gtcatcatta tgcttgtact gctggtttta
    15721 tttcaacatc atcgctataa gcagcagcag gctaatcttc tttatgcttg taccaaatta
    15781 caagccatta ccaatcaaca tacagatgaa aaactgctgc tgcatacaga ggatattcat
    15841 ctgaaaaccc ttttgaatga gattaaccgg ctgttggagc aaaatcagaa aacggtcgct
    15901 tcctactatc agatggaaat atccatccgt aaaatgttat ccaatatttc acatgatttg
    15961 cgtactccac ttacggttgt gcttggttac attgaggtca tcctgaatga ccctacacta
    16021 accagatccc aagtggatgt tttgcttgcc aaagttcatg acaagacgat cgaagtgctc
    16081 agcttaatga aaaagttttt tgatctggtc aagctcgaat ccggtgatca cgatatcgaa
    16141 atttccaaaa ttgacgtaag tgagatttgc aaagcgaata ttttaagctt ttacgatatt
    16201 ttgactgctc aggatattga agtcgtcatc gatattccgg atgacaaaca ttatatggct
    16261 tatggaaatg aagaagagtt aaaccggata ttaaacaatt tattatcaaa tgcggttcag
    16321 tacggcagtg agggaagagt actggggttg tcggttcatc agcagaatca gcatatatgt
    16381 atcgatgtat gggacaaagg taagggaatt agcgaaaagc acaaagatcg tgtgtttgag
    16441 cgcatgtata cgctggaaga ttcaagaaac cgactatacc aggggagtgg tctgggatta
    16501 accattacca agcgtctcgt ggagaaaatg ggcggagaga tttcatttgt cagtaagcct
    16561 tatgaaaaga cggtatttac cgtaatgctt aaacgataca ccacataatc caattatcga
    16621 gaatacccta ctggataaag gggatatcga ggataggtat tcctttctca cgaaattaag
    16681 gaataagtaa gagttgatta ataaaaaagc aatttcactc ctgtaaagta aaagtataag
    16741 taatccatta cacttaggag ggaaatccag tgacatattt aattaaaacc catcaattaa
    16801 gcaaaagcta cgatggtcat gaagtagtct ccaatttaaa catgagtgtt aaaaaaggag
    16861 aaatttatgg ttttcttggt cccaacggtg caggtaaaac aacggttatg aaaatgatga
    16921 ccaatctgat caaaccgacg agcggggaga tcgagatttt cggtgaaaaa gtgaccgagc
    16981 attcctatga gatgttaaaa agaatcggca gcattatcga attcccggta ttttatgaaa
    17041 agctgagcgc gcgtgagaat ctacagctgc attgtgaata tgccggttat tatgatcatc
    17101 aggcgattga agaagcactg acacttgtaa atctgcagga tgtgaataac aagcctgtaa
    17161 aaagcttctc cctcgggatg cggcagcgcc ttggtatcgc tcgtgcgatt atgaccaaac
    17221 cggaactgct tattctggat gagcccatca atggactgga ccctatcggc atcaaagaac
    17281 tgcgcagtct gttccagatg ctgtgccacg aataccggat taccatgatc atctccagtc
    17341 atattctgag tgaagtggag cagattgccg atacaatcgg tgtcattaac aagggccagc
    17401 ttattgaaga gattaccgtc aaagaaattc atgaaagaaa taccgagtat atcgaaatcc
    17461 tgagtgatga tgtcaaaaaa gcagtgtatg tgctggaaga agttctatgt atcgataatt
    17521 tcaaagtaat cgatgattcc cggatacgca tttataatct gtccataaca caggcagaga
    17581 tttccaagca atttattatc aatggagtca atattgaaga aatgaagaaa aagagtcact
    17641 cgctggaaga ttattttgtc aatctactgg acggaggtct aaaacatgct taaattactc
    17701 cgattggaaa tcaaaaaata tcacttatgg cgttatatga aaggcgtaat tatcgccaat
    17761 ctttgctttc tgtccctatt ggtactcatt tacgtgctcg aaaaaaatga cggcaatatt
    17821 ccttttgaaa gttatgatat ggcattcagc attattggca gcgtggtgcg ggcgaccttc
    17881 accgtatttg ccgccgtatt gattaccagg ctgtttttgg aagaatacaa gaccaagtcc
    17941 atttccgtgc tgttcatgta tccaatcaaa agacagaaaa ttatgctggc caaagtgctg
    18001 ttgattatca tttttacctt tgcaacgatc ctgctgtcga acatacttat gggaagcatt
    18061 ttctatctga tgaacaaagt gcttcatttc ctggctgaac cgatgacttc cgatattttc
    18121 atgcgtaatg ccctcagcgt attgatcagt gctgcggcat ctgcaggtat tggcctcatc
    18181 ccgctgtata tcggaatgcg ccgcaaatcc gtacctgcca cactcgtatc tgccgtattg
    18241 attgtagggt ttaccagtgc taccagcaat gatttctcaa tgtttgccat tacagctgtt
    18301 cctgtgagtc tggctgctgt tggtctgctg tctgcctatc tgtccattcg caatgtggag
    18361 acgaccgata ttgcataatg ggcaataaac tgcactctaa ccgtctcaga tcaatggtcc
    18421 agattcaata aaggagaagc catgattaat gcacaattca aaaaaggtgc acttgaactc
    18481 tgtgtgctgg tattactgct gcataaagac cactacggat atgagctggt cagacaaatt
    18541 tccgaagata tagacatcgc ccgcggtaca ctatatccgc tgctaaaaaa aatgcaaaaa
    18601 gatcagtatc tgtccaccta ttttgtttct tccacagagg gccctcaacg aaaatattac
    18661 gctattacgt atctgggcaa agagcgaatg gaaagtttat tacaggaatg gatgcatttt
    18721 tccgaatcgg taaccagaat tctacagaaa aattgtgtac ttagtaaggg agaggaaggc
    18781 ttttgaaacg ttcaatatcc atactcgtta cagttatcat tattgttgcc atccttgtaa
    18841 tcggttatct cgtgtataac cgtgttaccg gagcagtcac gatccatgaa gaaaagactt
    18901 tatccgcgtc agccatcacc agtctcaaaa ttgatacgtc atcagccaat gtggaagtgc
    18961 tgccaggcga tggggagaat attgttgcta ccctggatgg cgagatcagc ccaagattag
    19021 aaggcaaata tacctttaat atgacgcctg aacaaaacgt cgcgaacatt caactgaaca
    19081 tgggcaacaa tgtaatgggc atacagctgg atgaggtaag caaggtaggc ctgaaaataa
    19141 tggtaccgca aaaaacatgg gatcaaatgg aagtaacgac cacgtcgggg caaattacac
    19201 tgcataatat tgccgctaac aagctgacga cggaatcgag ttccggtcaa cagcatatat
    19261 ccggattaca aatttccggt tcggccgcat tccagacaac gagcggagat atcatggccg
    19321 aacaaaatga gattgcttca gccaaatggg aaacgacaag cggcaaaatc cagactgccc
    19381 agttatccgg gcaaagcagc gagatgcaga caacgagcgg agctatcgag tatacccaga
    19441 atgagctgtc tccgagcgta cagctagcga cttccagcgg tgatattgat gccaaactga
    19501 ccggaaatac ggattcgctt caattgcaat ttgagagcag ttcaggtacg gcagacatcc
    19561 agatagaagg catgctgtac aaagataagt ctgagcacag tgccctcgga atcaagggcg
    19621 aaggagaagc ccagcatcgg atcatgctca aaacgagttc cggtgatgta caggttggcc
    19681 cgtaataata tcatgcaaaa aagataaaaa acgacctttc ccattcggga aaggtcgttt
    19741 ttatatccga taaattgcat aaatattttt ttaaatcgtt aacattgtag ttattttgta
    19801 tatattataa atattaataa aaaagtaata aacaattaat aattccactt attgttataa
    19861 aaagaatttc tgctatatta tttactagga aacatagttg aacagtgagg tggaaaaatg
    19921 ctatggacaa aacaggatta acggatcgaa cggtcagttt gaagcagagg ttaagccttt
    19981 accaaaaagg aaggcagacg ttgattccgc gtaaagtgat ggcgcagggc gaaggatatg
    20041 ctttatcggc ggctcagcag cggttatggt ttttggaaaa gatggctcct cattccgcca
    20101 tttacagtat accgcaggca ttatccatac atggtttgct ggatgtaaaa agaatgaaaa
    20161 cggcggtccg gcatatggtt gaacggcatc cgattctgcg aaccgtttat caggaagatg
    20221 agcagcttaa cgaagtgaaa cagtatattc atccggttcc tcccgatctt gttcatttca
    20281 tttccatgga taccgttatt ccggatatga gggaacagca ggccaaagag atgattgcca
    20341 agctggctgc aattcctttc aacattgatg gcgggcattt gtttacagcg catctgttcg
    20401 agctgaagga cacacagcac attttatttt tgaattttca tcacagtatt atagatgggt
    20461 ggtcgatggg gattttctgg aaagagctgc ttgcccatta tcaggaacag gcggaacact
    20521 taccggagct atcgattcat tatcatgatt ttgcggaatg ggagaaacag catcattctg
    20581 aagcagccag acagcatttg ctgtattgga ccgattattt gcagggcacc tcaatggttc
    20641 ggctggatca cgatttgagc ggcacgatcg atcctgcgat gcatcaggga ggaatcggtg
    20701 agcgatcgat cccgtcatca accagcaggc gtattatcga atattgccaa gcgcaggaag
    20761 ttacgccgta cctctttttt atgacagcat ttcatttact tctacataaa tataccggag
    20821 agtatgacat tactaccggt acccctacat ccgggagaat acatacagaa acacataatc
    20881 tgattggctt ttttgtagac atgatggcta tccgcacaca gatcagtgag gagcaatcct
    20941 tccatgatca tctggcactt gtcaaacaaa atgtaataac ctgcatggat catcaggcgg
    21001 tatcttttga acagattgta caggctctgc agcctgaacg tgaacttgct gccagtcctt
    21061 tgttccagct gacgttcgca tatcagcagg agggtgagat gcctgccatg gagcagcttc
    21121 gtctggagct tttcccggtg gacaatcata cttccaaata tgacataagt gtatttgtag
    21181 gtctgcaaaa tgatcagtcc tttcatatcg tgtgcgaata taacagtgca ctgtacagtg
    21241 ctgatcgaat cgcgcagttc cttgatcatt atgaacagct ggttgtccag attatggcgg
    21301 accccggtat gcctgtatcg gatctgcaaa ttattacctt gcagcagcaa agccgattat
    21361 taaatgcttc atcgtacttc ccggatgctc ctcatacttt cctttcattt aaagacagat
    21421 tcgaatatta tgcccaaact actccggatc aaacggcatt ggtgatcgat gaccgggagt
    21481 atacgtatgc cgaattgaac tcaaaagcca atcggatagc tgcctgtctg caaaaaaata
    21541 atattcggca tggcgagttt gtcggtgtac attttgcaag gtccgaaaaa tccattatgg
    21601 ctattctggg gattatgaaa gccggtgctg cttatgtacc actcgatccc gcctacccgg
    21661 cagaacgctt aatctacatg gtggacaaag ccggattgca gtatatagtg tctgatcaga
    21721 ccagccagat attttctgat catataagcc tgttgtctat ggaacagctg ttgaatgaaa
    21781 cagaatatcc ggcagcgcct cagccgattc atctgcttcc tgaagatacg gcgtatatga
    21841 ttttcacttc cggatcgacc ggagcaccca aaggtgtcgt tattgaacat ggcagcctga
    21901 gcaatctgat tgatgcacag cagaccgttt tcgatttgca tagtgacgag cgggttctgc
    21961 agtttgcttc acttagcttt gacgcctcgg tatgggaaat ggtgatggct cttggtcatg
    22021 gttctactct gtgcatgttg ccttcggact ggaaagatat gcagcaggat atgatcagtt
    22081 tgtttaaccg gtacaaaatt acgattgcta ctttcccgtc ttcatttctg gtgaatatgt
    22141 atccggaaga gctgccttcc ttacggaaag ttattgtggc cggtgaacga tgcccggtag
    22201 aactggctgg cagatgggca gcatccaaat tattctggaa tgcgtacgga ccttccgaga
    22261 ctacagtgtg tgcgacggtg tttccttatg tggcaggcag cagggttccg atcggttatc
    22321 ctctgccgaa tatgcaggct tatgtactgg atgaacaaaa gcggccggta cctccaggga
    22381 gatcgggaga actatatata ggcggagtgg gactggccag ggagtatttt gctgatgctg
    22441 ctcaaaccgc cgcaaaattt atccattatc cgatagggga taatgatcag cgtctgtatc
    22501 gcaccggcga tatagtgaag tatgataacc agggcgtatt ggaatttatt gatcgcattg
    22561 ataatcaggt caaaatcagg ggttatcggg ttgaacttgg agaaattgag catcagttaa
    22621 gtctggttgc cgggatcagg gaaactgttg tgatctgtct ggagcgcccc aatcagacag
    22681 cggagctgac agcttatatt gtctgcgatg tacgcggtgc ggttaaccgg atggatatca
    22741 tggatagtct gaatggacgg ctgccatcct atatgattcc ggcaaatatt atagagctgg
    22801 agcatatgcc tctgactcct aacggcaaaa tagacaaaaa gcagctgcca cttccggttg
    22861 taatgaacga gccggtgcct ggaacagata tccagcgcga tcttactcct gcagagcagc
    22921 agctggttgc agcctgtgaa aaagtattga aacgtacggt gcgaatcacc gatcattttt
    22981 ttgaatccgg gggcgactcc attctggtac ttaaattaat taatgagcta aaaaccttgc
    23041 agtggagtct gacaccgcgc tctttttacc agtacccggt attggaagct ttggcgcaga
    23101 aaatgcagcc gcttgtggag cagtgcctgg agccggagac ggagcatgaa tggttttctc
    23161 tctctcccat gcaaaactgg ttttttgaac agcagtttgc cgatgcgcat cactggaatt
    23221 attcactatt gttcaagatg cctctgcatg ttgaaccgga aattattgag caagcgctgt
    23281 accgattgta ccggcagcat gatgcaatgc gcctgcaatt tcattacacc gctgagggga
    23341 tgcgtcagtc gtaccgccag catggagcaa tcccactgca tattgtagat cagcctgccg
    23401 gttgttccat ttcggaattt atgcaggata cgggtgcttt tcatcagcag tccctgaacc
    23461 tcagtgattg cctgatcaca gcggtgctca tgcgcaatac agaacacaaa cagcagcatc
    23521 tgctgctcgt ggttcaccat ttgctgacag attgggtcac ggggggcatc attgcagaag
    23581 atttaaatca gtttgttgaa gaagcgctgg aagacaggga aaaccggctt ccgtcatttt
    23641 ccctatcatt caaaagctgg atcgattatc tgtcgaggca taccctgcag cagccggtgc
    23701 aacaggatct gccctactgg cagatgacag aacattcaca gcgtctggtt ccatccgtac
    23761 ctcttgatcg gcctgacggt atcaatctaa aaggaacggt gaaacatgta actattgcat
    23821 taacgatgga gcagaccaat gatctgatcc gcatcagtca ttaccatttg aattcagatg
    23881 taaaaacagt tcttttgtct actgtgctgt atgcgatccg ggcatggtcg ggaatggaaa
    23941 gtattgcact ggatatggcg agtcatggca gacatgattt gtgggaagag gtggacatta
    24001 cccgtacggc tggctggctg accagtgtct atccgcttgt gctgcaatcg aaaggacaac
    24061 aaactctcac agaatacatc tatcatgtgc agcaggccat acagctggtt ccccatgaag
    24121 gaataaccta tggaatgctt cgttattatg cggcagagca gcggctggac ggatacaact
    24181 ccgaaatctg gttcaattat tttggccata atcattcatt ggataacagc ccgaatacgg
    24241 aaaataaggc acctctgctg gaattatgtg atgacctgct gggcagcatg aacagttatc
    24301 agcagcagcg cagtcatgtt tttgagattc tgggcatgat tcgggaaggg cagctgcatc
    24361 tgggatggca gtattcggaa cagcttcata atcgggagac cattcagcag ctggctgatc
    24421 atgtatacac tgaactggct cagctgattg ccgaactaaa ggagacgtat atcaaatgat
    24481 gcataccacg aatgtcatca ctactttcaa aacagtgccg gagatcttcc gtgaaagcct
    24541 gcgggagtat ccgcattgtg tcgcaattga aaatgattgc agctctgtga cttatgctga
    24601 gcttgatcag tattcagatc gtatcgccgc tggattaatg gaacgaggag tcaagcaagg
    24661 cgatatggtg gggacattga tggagcgttc acctgaactg tttgccagct ggctggggat
    24721 attaaaagtc ggcgcaacct atgtacccgt agatccggcc aatcctgcag agcgcataaa
    24781 gtatattgtg gaagattcgg gaatggcgta tttaataacg gatcagggta atcggcaggc
    24841 accgattgcc agtctgaacc tatgcgcttc cttgcatgta gaggaactgc taagcgaacg
    24901 atcgttaatt tcctttcatc aaaatacgta taattcggat aacatcgcat atatgatata
    24961 cacttctggt tcaaccggca gaccaaaagg ggtacggatc acggacagag gtattgtcag
    25021 tcttgtacaa aatagcacct atgcgcagct ggaccacacg gatattattg cccaggcgtc
    25081 aaatgcatct tttgatgcga ttacttttga ggtatgggga gcgttattga ccggagccag
    25141 agtggttatc gctccaaggg aaaccattct ttctgtggag cggttcagtg catggctggt
    25201 cgataagaat ataaccatat tatttattac cgtagcctgg ttcaatcata ttgcccgtca
    25261 tgaaccagct gcatttgcaa gtctgaaaac ggttctgttt ggtggcgaag cgtgcaatgt
    25321 ccgctggatt aatgaagtat tgcgtgcagg caagcccctt catctctcca atatttatgg
    25381 tccaaccgaa tgcaccacct tctcgctgag ttatgaaatt acggaaaaag agttggatga
    25441 acagcaaaaa gtgccgattg gaaagcccat caatcatact ctggcctaca ttctggatga
    25501 gcggcagcag ctagtgcctt atggagtgac cggagagcta tatatcgggg gtgaaggact
    25561 ggcagcaggg tactggaacc gtccggagct gaccgctgag cgatttgttc atctgccgca
    25621 gctggcggat ggaccgttgt accgtaccgg tgatctggtc cagcggcgag cggatggcca
    25681 gattgacttt atcggccgaa ccgatgatca gatcaagctg cgcggtcacc ggattgagct
    25741 gggagagatt gaagaagcgc tgcgcagctg cccgggaatc tgcgaggcag tggccgcatt
    25801 gactaccgta tccggtcagg aagagccggt gctggctgtg tactatgcga ccgaacaaga
    25861 gctggaggcc ggacagctgc gtgaccagct gcagcagcgg ctgcctgcct atatggtgcc
    25921 cgctgcctgg cgggaagtgg agtcatttgc cctgaccgtc aatggcaaga ttgaccgcag
    25981 acagctgcca ccgattcagg aacaggatct gcgtcagcag gcgtaccagc agccggatcg
    26041 accgggagaa gcagagatag ccgccatctg ggcggatctg ctgaaccggc agcagattgg
    26101 cgcccaggat catttcttcg ctatcggagg gcattccttg ctggcggcgc aggtcgtcag
    26161 ccgcatggaa gaacagctgc agcggcaggt gaccctgcga gccctgttcg attatccggt
    26221 gctgcgggag ctggcagcgt atgtgcagca gcagccggta agcggcccgg ccagcgtgat
    26281 tccggcctat gtctcggaag atggtcgtta cccgttatca ccggcgcagc agcggctgtg
    26341 gctggtccag cagctggaac cggacagcca ggcgtatcat attccttttg cctttcatct
    26401 gtatggcatt ttggatgccg atcgactgga gcaggctatt cacgaagtgg tggagcgcca
    26461 tgacagtttg cggacgcagt ttggagaaga gagcggggaa ccgtatcagc aggtaaccgg
    26521 caatttgccg gtcctggagc gttcgagtct gcatgtgccg gtaggagagc aggagcagca
    26581 tctgcaggag gtactgcagc gggaagcctg ggagacgctg tcgctgacgg ctgcaccgcc
    26641 gctgcgcctg cgcctgattg agctggaagc aggtcaccat gtgctgagct gggtgatcca
    26701 ccatat
//
