LOCUS       NZ_KQ040793            24784 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Paenibacillus wulumuqiensis strain Y24 Scaffold4, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ040793
VERSION     NZ_KQ040793.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus wulumuqiensis
  ORGANISM  Paenibacillus wulumuqiensis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1  (bases 1 to 459295)
  AUTHORS   Wu,Q., Zhu,L., Jiang,L., Xu,X., Xu,Q., Zhang,Z. and Huang,H.
  TITLE     Genome Sequence of Paenibacillus wulumuqiensis sp. nov., a
            Bioflocculant-Producing Species
  JOURNAL   Genome Announc 3 (4), e00795-15 (2015)
   PUBMED   26184946
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 459295)
  AUTHORS   Wu,Q., Jiang,L. and Xu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2015) College of Biotechnology and Pharmaceutical
            Engineering, Nanjing Tech University, No. 30 South Puzhu Road,
            Nanjing, Jiangsu 211816, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000971965.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 14:25:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,570
            CDSs (total)                      :: 4,478
            Genes (coding)                    :: 4,431
            CDSs (with protein)               :: 4,431
            Genes (RNA)                       :: 92
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 10 of 47
            Pseudo Genes (incomplete)         :: 37 of 47
            Pseudo Genes (internal stop)      :: 6 of 47
            Pseudo Genes (multiple problems)  :: 6 of 47
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:39:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 386455
            Orig. end                         :: 411239
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ040793.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24784
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24784
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24784
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14784](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14784)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            816..1592
                     /locus_tag="WH45_RS04680"
     CDS             816..1592
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811543.1"
                     /locus_tag="WH45_RS04680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_046213231.1"
                     /transl_table=11
                     /translation="MLRQSRKNVVFVLVFAALFLIIAGCGNNNGTGSSTSGQTGTSTGT
                     ETNGSSGSTGSTESSSETGSAATDTAQTESANDNSADFKQANDPIVTVEMDDGQKIEIE
                     LYPKAAPNSVNNFISLVKKGFYDGLTFHRVIPGFMIQGGDPKGDGSGDPGYSIPGEFKS
                     NGVQNDLKHTAGVLSMARAGDPNSAGSQFFLMVADAPHLDGEYAAFGKVISGMDEVNKI
                     VNLPRGANDKPETPPVMKKVTVDTKGVDYPEPEKTK"
     regulatory      1894..1988
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            2108..2917
                     /locus_tag="WH45_RS04685"
     CDS             2108..2917
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811544.1"
                     /locus_tag="WH45_RS04685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_052723617.1"
                     /transl_table=11
                     /translation="MTSAHAQSAQKATWLWNTQLIVDSTASILSFAAAQNVNLIYLQVN
                     ADLDADYYHRFISAASAQGIAVQALDGAPSWALDSRRHELQATLDWIATYQNTASADKK
                     FSGIHIDIEPYLLPEWRSDQTSVIAGWQQSVQQVVQAARALHIPASADIPFWLHTLLTA
                     DESATLSSWMMQQYDSITIMAYRDTASGILDVAEAQLAEGDAVGTPVYVGVETNPSAEG
                     DNITFHEEGAAYLNNQLATVIKQAGTHESFAGIAVHDYAGWSALMQQ"
     misc_feature    3126..3143
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            3230..3958
                     /locus_tag="WH45_RS04690"
     CDS             3230..3958
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811545.1"
                     /locus_tag="WH45_RS04690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_046213232.1"
                     /transl_table=11
                     /translation="MLHKQKWLLVLLIAVLLIPQTATAAKSEGISKNKSHSSKVIYLTF
                     DDGPTAHTMQLLDILDQYNAKATFFMLGPHMERFPAATKRIVKEGNGLGLHGVTHVVSK
                     FYSSPYSAYKEMKGANESLHKVTGKYTSLVRTPYGSKPYLKKSYRDIMLSTGGFHLWDW
                     NVDSLDWKYKKDHQKVYNNVMSEVKSAERRGMDPVILMHDQPATLKVLPSVLKELKAEG
                     YQFKILDKQVRPLNFWNDRR"
     gene            4167..4787
                     /gene="cysC"
                     /locus_tag="WH45_RS04695"
     CDS             4167..4787
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811546.1"
                     /locus_tag="WH45_RS04695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_046213233.1"
                     /transl_table=11
                     /translation="MTESQRHVTAGYPSVTRADRERHYRQRGRVLWLTGLPGSGKSTLA
                     FALEQELFLRGQLGYVLDGDRMRQGLNRDLGFAPQDRRENLRRIGEVARLLLDSGQIVI
                     AALISPHAPDRQMVREMFQPQDFCEIYVNCSLEVCEQRDPKGLYRRARSGEIPEFTGVS
                     APYEVPEQPELVINTEFLSVEESVMLIMETLELAGMPSMDVSR"
     gene            complement(4864..5697)
                     /locus_tag="WH45_RS04700"
     CDS             complement(4864..5697)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017692154.1"
                     /locus_tag="WH45_RS04700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_046213234.1"
                     /transl_table=11
                     /translation="MRQTVLLTLQEQPYFCLPESIGHYQQQPEHTVLREEGALNNFNIH
                     YVAAGKGYVEVEGTVHELRSGQAVLYFPHQRQRYYSSEDDPWDVRWVHFYGERLHDYMI
                     ERGFHRHLLWTLRQREAWEMAHLALLEEAEQHRMLHPALLSTLTYAVLAEFVHQAVPLK
                     NRRAGQAENRILSLLPQMQQEACEPFLLQDWADRAGVSVHYFCRLFKSVVEMTPLEFVT
                     RSRLQMAKQWLLERPDRHIGQIAEDAGYPSVSYFNRQFLTREKMTPTEYRRLYWS"
     gene            5831..6757
                     /locus_tag="WH45_RS04705"
     CDS             5831..6757
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811548.1"
                     /locus_tag="WH45_RS04705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_046213235.1"
                     /transl_table=11
                     /translation="MEYIQIEGARKPVSRLIKGTDYFRHDTYEKAAGNLDAFLSIGGST
                     IDTAHIYCGGESEEVLGKYMQERGNRESIVILTKGAHHDQNGPRVNAEAIRSDLLTSLE
                     RLQTDSVELYALHRDDPSIAVGTILEALNEHLEAGRVRAIGASNWTWQRLQEANDYAAS
                     HGLTGFSFSSPNLSLAKANEPFWPGCVSADRQMLDWHEQTQLPLLSWSSQARGFFTGRF
                     TPEVRDNEDLVRVFYSDDNWERLHRAEQLAGQKQTTPIQIALAYVLNQPFPTCALIGAQ
                     NREELLSCDEGARITLSREEVDWLDLK"
     gene            complement(6983..8779)
                     /locus_tag="WH45_RS04710"
     CDS             complement(6983..8779)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811549.1"
                     /locus_tag="WH45_RS04710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_046213236.1"
                     /transl_table=11
                     /translation="MNELRSYVNELRQYGGKRIYFYIGLMLVISLLDMVTLYMLVPLLS
                     LIGVFGGGGSSTLPMAGLFEPLKQMPVTTTLIIILSVYSLLTIMQGLMQRKQAIMGAEI
                     QQGFIKNLRLRVYRSIMRSNWSFFLRKRKADLSHMLTTELARVSQGTNLVLMLSTSLLF
                     TVIQIGFAMVLSFKMTLLVMIGGGLLALYSRKFVRRSKSYGDKMTQLSQDYFSGIQENL
                     NGIKDIKSNMLEASHFDWFRKMANKLEYNLIQQIRLNSATQLIYKLISVVFIVGFIVLS
                     AQVFKLQPERSVLIVLIFARLWPRFSGIQSYLEYIGALLPAFRALSKLQAECEQAEESY
                     RPVGYGQGPVQPLQQGIRCEQVSFRYSEEHGNALQNINLFIPAGQMTAVAGRSGAGKST
                     LIDMLMGLMEPQEGQVTVDGEVLTGERLLSWRNSIGYVAQEPFLFHSSIRENLLLVKPD
                     ASEDELWEALSFAACEEFVRQLPGGLDTVIGDRGVRLSGGERQRIVLARAILRKPEVLI
                     LDEATSSLDTENEAKVQLALEKLKGKITLIVIAHRLSTIRNADQVIVMDHGQIVQQGGF
                     NQLSNETKGTFHQLLAYQTAAQ"
     gene            complement(8776..9969)
                     /locus_tag="WH45_RS04715"
     CDS             complement(8776..9969)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.5"
                     /locus_tag="WH45_RS04715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_046213237.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 8.1e-65, bitscore:
                     213.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKEWGLDLRNFPVELKLMLGSMKDKPADLLLAGMGPALDWQEFS
                     SLSMHHRVYPTIHAHLSRQSELLPKETMQWLNHRYHHNTFTMLQLSGQMQKVSQKLSDE
                     KIPALQLKGPVLAQLLYGDLSRRTSKDLDVLVPMDRIEEAEQALLELGYTKTQAVDRAL
                     DKWKWRYNHESYTHERTGVEIELHWRLNGDAGAEQSFDDLWARRQTLTFGGTAVHMLGK
                     EDLLIYLAVHGARHAWFRLRWLADMDKLVQMDIDWELLSRLVRQYKCSHIIGQAFLLSA
                     SLLETPVTPQMEALMNRPRAKDLAQRVIVFIREKVSLCPEPETEQLAQKYRSYQYALRT
                     NGQKALFWWRKMTPDAWDMQTLPLPKPLHFMYYPLHPFLLLYRRNQRRSALQREVGQ"
     gene            complement(10001..10465)
                     /locus_tag="WH45_RS04720"
     CDS             complement(10001..10465)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014461231.1"
                     /locus_tag="WH45_RS04720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_407668013.1"
                     /sec_met_domain="PF13471 (E-value: 4.9e-24, bitscore: 79.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFAKLSKVAKLRSYPASMRKLMLEALFYLAWGRIMKMRPFAK
                     VSPSLGDYMQETSYESDRDAHREAVQISKALHLVSPHVFWETECLVMAFAAMKMLERRK
                     LPSTLYLGMRRDAKGSNAAHAWLRSGRFYLTGAKEIEQYTVVGRFAKQFN"
     gene            complement(10446..10748)
                     /locus_tag="WH45_RS04725"
     CDS             complement(10446..10748)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811551.1"
                     /locus_tag="WH45_RS04725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_046213238.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-28,
                     bitscore: 93.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.4e-17, bitscore: 58.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKNLINAEQKITQNSNYIASDMNGEKVMLDIESGKYYNLGAIGG
                     RIWDISENPVTVDEIVAVLVQEYEVEPEVCKQQVSTFVEKMLQEGLVEVNGAAVR"
     aSDomain        complement(10467..10706)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_WH45_RS04725_Stand_Alone_Lasso_RRE.1"
                     /evalue="7.20E-30"
                     /identifier="RREFam002.1"
                     /label="WH45_RS04725"
                     /locus_tag="WH45_RS04725"
                     /protein_end="94"
                     /protein_start="14"
                     /score="93.9"
                     /tool="antismash"
                     /translation="NSNYIASDMNGEKVMLDIESGKYYNLGAIGGRIWDISENPVTVDE
                     IVAVLVQEYEVEPEVCKQQVSTFVEKMLQEGLVEV"
     gene            complement(10850..11737)
                     /locus_tag="WH45_RS04730"
     CDS             complement(10850..11737)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811552.1"
                     /locus_tag="WH45_RS04730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldolase"
                     /protein_id="WP_235338280.1"
                     /transl_table=11
                     /translation="MPELQQVNNTNRSADVTVRFADLSQWAEAISTRETNFTMQPPGFM
                     FQMPDTGIFCIHEGSSIVIDPSPQVSEAKLRLFVLGTCMGILLMQRDIFPLHGSALLIE
                     GQAYAFVGHSGAGKSTLAATFMQAGYPLITDDVIAVNYENGVPHVYPAYPQQKLWQESL
                     NHFGMSSDQYSTLHDEYDKFAIPVGDRFYNQPVPLAGVFELVKTDAPEASITELNRLER
                     LHIMLAHTFRGAIVPRLGLKQRHFSQIAALAGELDAYQIQRSTTAFTAPAIMDKVLDII
                     RSKNHAASRSGSNG"
     gene            complement(12069..12206)
                     /locus_tag="WH45_RS23335"
     CDS             complement(12069..12206)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811553.1"
                     /locus_tag="WH45_RS23335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_152663479.1"
                     /transl_table=11
                     /translation="MNNEKMQWQAPALEVLEMNETAAGKGWKAIDWVTYDDADLYNPGS
                     "
     CDS_motif       complement(12138..12206)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MNNEKMQWQAPALEVLEMNETAA"
                     /locus_tag="WH45_RS23335_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12069..12137)
                     /prepeptide="core"
                     /locus_tag="WH45_RS23335_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-13.10"
                     /molecular_weight="2453.6"
                     /monoisotopic_mass="2452.1"
                     /core_sequence="GKGWKAIDWVTYDDADLYNPGS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MNNEKMQWQAPALEVLEMNETAA"
                     /leader_location="[12137:12206](-)"
     gene            complement(12264..12398)
                     /locus_tag="WH45_RS23340"
     CDS             complement(12264..12398)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811554.1"
                     /locus_tag="WH45_RS23340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_145953903.1"
                     /transl_table=11
                     /translation="MNQEKMQWQAPSLEVLDVHQTAAGKGWRVIDWVTYDDADLYNPS"
     misc_feature    12433..12445
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.45"
                     /tool="antismash"
     gene            complement(12461..12598)
                     /locus_tag="WH45_RS23345"
     CDS             complement(12461..12598)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811555.1"
                     /locus_tag="WH45_RS23345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_152663480.1"
                     /transl_table=11
                     /translation="MNQEKMQWQAPMLEVLDVNETAAGKGWKVIDWVTYDDADLYNPGS
                     "
     gene            complement(12665..12802)
                     /locus_tag="WH45_RS23350"
     CDS             complement(12665..12802)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811556.1"
                     /locus_tag="WH45_RS23350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_200897658.1"
                     /transl_table=11
                     /translation="MNMTKMEWQAPEMQVLDVNETAAGKGWRVIDWVTYDDADLYNPGS
                     "
     gene            complement(12832..14784)
                     /locus_tag="WH45_RS04735"
     CDS             complement(12832..14784)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280290.1"
                     /locus_tag="WH45_RS04735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_046213240.1"
                     /sec_met_domain="GATase_7 (E-value: 2.8e-23, bitscore:
                     76.8, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.9e-21, bitscore:
                     71.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATAGIWDMAGRHNSEELQQQGNRMMQSMEKYPADASVVWQGEH
                     LFLGCHDQWVTPEAVNQQVPYYDAVRRMAITGDVIIDNREELFGQLGLNASMIDMPDIM
                     LLLHAYDKWGEQMPRYLNGDFAFAIWDESRQQLFLARDWSGNRTLYYYQTAEKFMFAST
                     MEALFQTGDVSKKLSTPWMAEFLTTVAMEESTDIQATVYEQIKQLPPAHAMVLSADKSS
                     IYQYGTLLPDELLRLKSDGEYVEAFRDVFERVIRAKVRTRHGIAATLSGGLDSGSVVSY
                     AAKILSGQNKPIHTYSFVPIPGFKDWTSSRLMANERPYIEETVRHVSKIHPVHDTYMNF
                     ADRSPLSEVEHWLSLMEMPYKYFENSFWIRGIFEQAQKQGAGVLLTGARGNFTISWGPA
                     IEYYGEMLKKFQWIRLYQEMKLYSQNAGIRRKKIIQQIQQSAFPKLSRSTRDLGRPDAL
                     KWINPELAERTGMAERVRRAELDLVGSDTMSDQDIRLGKFSNLATANKDGAVTSKISMG
                     YGVWERDPTNDPRIIKFCLSVPYNQYVQNGMDRALIRRATAGDLPDKIRLNQKVRGLQP
                     ADWVQRMLPMWPAFTSEIREICQDPAAAQWMNTGNIMEALKEVGDSPTAEAAFNPATRL
                     LMRSLIMGRFIRSLA"
     gene            complement(14902..15189)
                     /locus_tag="WH45_RS04740"
     CDS             complement(14902..15189)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="WH45_RS04740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_046213241.1"
                     /transl_table=11
                     /translation="MVTADGKTKLVNKRLIRAQQSDGSPTLTAGEPDHTINTAACRYPS
                     CALSETEAYQVISFIEHHQLRLLHYREQRDQLKQYSEQLLREIPTASCLH"
     misc_feature    15144..15159
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
     misc_feature    15628..15642
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.5"
                     /tool="antismash"
     misc_feature    complement(15665..15681)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.17"
                     /tool="antismash"
     misc_feature    15665..15681
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.69"
                     /tool="antismash"
     misc_feature    15676..15692
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.42"
                     /tool="antismash"
     misc_feature    complement(15696..15712)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 21.48"
                     /tool="antismash"
     misc_feature    complement(15736..15749)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.04"
                     /tool="antismash"
     gene            complement(15978..16958)
                     /locus_tag="WH45_RS04745"
     CDS             complement(15978..16958)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811559.1"
                     /locus_tag="WH45_RS04745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="WP_046213242.1"
                     /transl_table=11
                     /translation="MTKIMPLAQRGISNSRLALGCMPFGGGWDRTPFTDEHVKEAEAAV
                     DAALSIGITMFDHADIYTKGKAEQVFGRVLHNRPELREQIVIQSKCGIQLQDDELPGRF
                     NFSREHILNSVDGSLERLGTEYLDVLLLHRPDPLVEPEEVAEAFAALKASGKVRYFGVS
                     NMSAAQIAFLQQAIPDSFAVNQLEMSLGHLHFVDQVVHVNQAAGTSVNFAEGLMEYCRT
                     QHIQLQAWGPLAQGKFSGRNVDKEPEHIQATARLVQQLADEKETTPEAIVLGWLMRHPA
                     MIQPIIGTANPQRIQACQDAERQSELMTREEWYSLYVSARGEVLP"
     misc_feature    complement(16976..16990)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.52"
                     /tool="antismash"
     misc_feature    16999..17013
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.28"
                     /tool="antismash"
     gene            complement(17272..18273)
                     /locus_tag="WH45_RS04750"
     CDS             complement(17272..18273)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="WH45_RS04750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_046213243.1"
                     /transl_table=11
                     /translation="MGLLTFKNGMVLAGALFLGTVFQGGTVHALQYGGDIVPTLSSSVG
                     SNGTAKASVEETGYEAWRAFDNNETDDSYWRAPAGGMSSLSYELTQKQVVNKYTVQADT
                     YDAADAPKKWQFAGKIGSNWLVIDEQSNQSGWAPGEKRTFEVDNDVAYSGYALFITGNN
                     GSKWVGINDLELAQFDGNTNIIPAMSAPSPTPGNTTMAAGDTATASVNAESAWKAFDHT
                     LSSDSVWTSDSQRYVDASLTYTFSSPKVIKGYAIAVTSKPTAPVSWMLVGSNDGKEWEE
                     VIHEVKSSMRWEPGQKKIYAVDNDSAYKAYKLIINRNSGPTQVVVNEFELYQ"
     misc_feature    18250..18263
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.68"
                     /tool="antismash"
     misc_feature    18600..18614
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 20.08"
                     /tool="antismash"
     misc_feature    18705..18718
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     misc_feature    complement(18747..18761)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.53"
                     /tool="antismash"
     misc_feature    18907..18920
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    complement(18908..18921)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.03"
                     /tool="antismash"
     misc_feature    complement(18909..18922)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.64"
                     /tool="antismash"
     gene            complement(19002..20501)
                     /locus_tag="WH45_RS04755"
     CDS             complement(19002..20501)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019450.5"
                     /locus_tag="WH45_RS04755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="copper amine oxidase N-terminal domain-containing
                     protein"
                     /protein_id="WP_046213244.1"
                     /transl_table=11
                     /translation="MKRKLWITLPLVLLLIVLSGCQAVGNLDIKNAMIRNLDVKSMESS
                     QTLSVQLTPSSTASADDIKMATILNSLQLNIDSAKLQADGKISVKGAVQYSGQQLPYHL
                     YLDDKGMTIDLQGAKQPIYISFALNDSMTGLSGLSGSFATTSLQGEEQEFAKQIISFLY
                     THLPNPSDISVSSVQQEVYGENLDLTQLHVELTGQELITLVKPFLSSISQDEQGMRQLI
                     GTFYDFMASTLKKAGDQSSLDSMGSREKFVNNGYKEISKMLTLALKEYDSQLAELQESP
                     EFNTVFGPNTRVSTDVYFDKDMYIRKQSMELTIALPDTEYTPFSSIRITTASESWNING
                     NVTADPVDTAGGVLQVSEKTTPGTFLRNFEETSPLYMLLNNMNGITEKTAYFGDYGDHD
                     DIITRNRVTLVPAKDLAEALDAKMEWNASAKQLTLTDDITGAVTVLKLNSNQAVVDGQT
                     QTLSSKVINVKGKVYVPLRSVAGILGATVTSEGNGFTVHRK"
     misc_feature    complement(20575..20589)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.41"
                     /tool="antismash"
     gene            20722..21198
                     /gene="infC"
                     /locus_tag="WH45_RS04760"
     CDS             20722..21198
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="infC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811562.1"
                     /locus_tag="WH45_RS04760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="translation initiation factor IF-3"
                     /protein_id="WP_046213245.1"
                     /transl_table=11
                     /translation="MIKNEKIKASEVHLTGLNGEDLGIMPTNEALQMAKQLKVDLVCNS
                     LFSSPPPCQLIAAGAAKQNKQQAAKSDRPAKVKEIRLTANIEDHDYETKKNQALRILQS
                     GNAVLLVVKTQGSKEAAKAKSIIEDLLRDLKEVGKPQTGIQVSGKQSMVQVDPV"
     misc_feature    complement(21406..21426)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.3"
                     /tool="antismash"
     misc_feature    complement(21926..21940)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.38"
                     /tool="antismash"
     misc_feature    complement(22686..22699)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.88"
                     /tool="antismash"
     misc_feature    22686..22700
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.02"
                     /tool="antismash"
     misc_feature    complement(23403..23418)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.02"
                     /tool="antismash"
     misc_feature    complement(23631..23645)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.66"
                     /tool="antismash"
     misc_feature    complement(24157..24169)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.08"
                     /tool="antismash"
ORIGIN
        1 ataatagcat catgctagac aactccggca attacggtct gccggtcaat cagcttgtct
       61 tcagcggaga gccgctggcg gcctccatgc aggcgctgat catgtcgctg cagagcctgc
      121 tgacctttac atatggagtt atctccatcc agggttcccg gctgcagggc aattatcgca
      181 gcgtccttat cggattcctg aaaatgccgg ttccctatgc gctcgcactc ggtctaatca
      241 tgcatgcgct ggcgcttccg ctgccgaccg tactcgccca gccgctcacc tatgcccagc
      301 agtccatggt agcaatcgcg ctgatcacgc ttggcgcgca gatcgtcaag tatccgctgc
      361 ggctctatcg cagtgatatc tatatcagca tggtactgcg gctgttcggc ggcccgctga
      421 tcgggctgac gctgattctg ctgctcgata tgcacggtat tccggctcag gcgctgctca
      481 tcgcttctgc catgccgaca ggcgtcaaca cctcgatact cgcggaagag taccggaacg
      541 aaccggactt tgccgcccag acggtactaa tctccacgat tgtcaatgta tttacaatta
      601 cggcggttat tgccctgtcc ggacatctac agtaaataaa atatccgttt acgtccatat
      661 ttgcttcatc cccctgcctt ggtttaaagt catagtatat gtcctgcagt acggcctgtc
      721 tgttatgcgt catatcccgg tgaaataccg gccatttcgc gtaacggcag acggcgtgct
      781 gaggaactta taacccataa ggagtgagca catctatgct acgccaatcg cgtaaaaatg
      841 ttgtatttgt actcgtattt gcagcgctgt tcctgatcat cgcaggctgc ggcaacaaca
      901 atggaacagg cagttccact tccggccaga ccggaacttc cacaggcacg gagacaaacg
      961 gctccagcgg cagcaccggt tctacggaaa gctccagcga gaccggctct gcggcgacag
     1021 atacggcaca gaccgaatcc gcaaacgaca attccgccga cttcaagcag gccaatgatc
     1081 caatcgttac cgttgaaatg gacgacggcc agaagatcga gatcgagctg tatcccaaag
     1141 ctgcaccgaa cagcgtcaac aactttattt ctctcgtcaa aaaaggattc tatgacggcc
     1201 tcactttcca ccgcgtcatc ccgggcttca tgatccaggg cggcgatccc aaaggcgatg
     1261 gctccggtga tccgggttac agtattccgg gcgaattcaa gtccaatggc gtgcaaaatg
     1321 atctgaagca tacggcaggc gtactgtcga tggcacgtgc aggcgatccg aactctgccg
     1381 gctcccagtt cttcctgatg gtagcggacg ctccgcatct ggatggtgag tatgcagcat
     1441 ttggtaaagt gattagcggc atggatgaag tcaacaaaat cgtcaatctg ccaagaggcg
     1501 cgaatgacaa accggagact cctcctgtaa tgaaaaaagt aacggtagac accaaaggtg
     1561 tggactatcc ggaacccgag aaaacaaaat aagacagcac accgaaccgg cgctttccat
     1621 ggcgccggtt ttttgctgca ttcatttcta tctactgtac agcctcctgc catttactgc
     1681 ttctgcaaat ggtaggattc ttaccaactg gtacttatac gccgtatcgt ttctattctt
     1741 ctgcatacac cgttacggct gttcactcaa tcaataaaaa tgtcaatttt tgtcgtataa
     1801 attatgaata ttctatttag aaacttagct aatgcgacga tatatatgct atgcaatctc
     1861 ccggagaatg catgtgacta tattgcttat catatttaat cagggcaaac tcaccgaaag
     1921 gtgaagacgc aaagccaagg gtctaaggtg tgatgggcag gatcgcgcta tgacagccgg
     1981 ttgccgatga atacctgatg cggtatgact cgaaggagtc cgattcacca tgagaaacac
     2041 tgtatatttc cgacacaaaa tgggtatcct ctctatagtg ctattactct tgctaggagg
     2101 attcccgatg acatccgctc atgcccaatc ggcccagaaa gcgacctggc tgtggaatac
     2161 acagctgatt gtggattcta ccgccagtat tttatctttt gcagcagccc agaacgtgaa
     2221 tctgatctac ctgcaggtca atgccgatct ggatgctgat tactatcacc gctttatctc
     2281 tgccgcttcc gcccagggaa ttgccgtgca ggcactggat ggagctccct cctgggcgct
     2341 ggattcccgg cgtcatgaac ttcaggccac gcttgactgg attgccacgt atcagaatac
     2401 tgcctctgca gataagaagt ttagcggtat ccacatcgat atcgagcctt atctgctgcc
     2461 cgaatggcgc agtgaccaga ccagtgttat cgccggctgg cagcaaagtg tgcagcaggt
     2521 cgtacaggct gcacgcgcac tgcatatccc cgcttctgcc gatatcccgt tctggctgca
     2581 taccctgctg accgcagacg aatctgcgac gctcagcagc tggatgatgc agcagtacga
     2641 ttccattaca atcatggctt accgtgatac cgcctccgga attctggatg tcgccgaagc
     2701 ccagctcgcc gaaggtgatg ctgtcggcac acctgtctat gtaggggtag agaccaatcc
     2761 ttcggcggaa ggtgataata ttactttcca cgaagaaggc gctgcctatc tgaacaacca
     2821 gcttgccaca gtgatcaagc aggctggcac gcatgaatcg tttgccggaa ttgccgtgca
     2881 tgattatgcc ggctggtctg cactcatgca gcagtaagaa tactatctat gaccgaagaa
     2941 gcctggaaaa gagtctatct cttccaggct tcttcggttt attttatgta agcgtctata
     3001 tattacaatc gtctgtatag tataccaggg catatacgac cagctgctta tctctctgtc
     3061 tttagtcctg gttctttaat tttcaatatt cgcaatttga cgtttttgta gtttcctggc
     3121 gattaatgta acaaaaatgt tatgcaatag tatccattta cggaagattc atagcttcca
     3181 gtcttgttat gatggataca gaaaattgca ggtaaggagc gtcttattca tgttacataa
     3241 gcaaaaatgg ttactcgttc tactcatcgc cgtactgctg attccccaga cagcaactgc
     3301 tgccaagtcg gaaggcatca gcaagaacaa atcgcattcg tccaaagtga tctatctgac
     3361 ctttgacgat ggaccgaccg cacatacgat gcagctgctt gatattctcg atcagtacaa
     3421 tgccaaagcg actttcttta tgcttggacc gcatatggaa cgttttcctg cagcgaccaa
     3481 gcgaattgtc aaagaaggca acggccttgg actgcatggt gtcactcatg tggtgagcaa
     3541 gttctacagc tctccataca gcgcctacaa ggaaatgaaa ggtgcaaatg agagcctgca
     3601 caaggtaacc ggcaagtaca ccagcctcgt ccgtactcct tatggcagca aaccgtatct
     3661 caaaaaatcc taccgggata ttatgctgag cactggcggt ttccatctgt gggactggaa
     3721 tgtggattcc ctcgactgga aatacaaaaa agaccaccag aaggtctaca acaacgtcat
     3781 gagcgaagtg aaatccgctg aacgccgcgg catggacccg gttatactga tgcatgatca
     3841 gccggccacc ctcaaagtac tgccatccgt actcaaggag ctcaaggcag aaggctacca
     3901 gttcaaaata ctggacaagc aggtacgtcc cctgaacttc tggaatgaca gacgctaagc
     3961 cgctgtaatg gctcccagaa tacagcaatc agcatagatc aacccatcac cccatccaca
     4021 gcgaaagaac attcgctgtg gatggggtga ttttatttgt tggcatcatc attcctccct
     4081 gtatccgcag acatcgccta gagacaatca ggaagcattg ctgttatgat aaagtaaatc
     4141 catctggtga ataaaggagc ataattatga cagaatcaca gcgtcatgta acagcaggct
     4201 atccttctgt tacacgtgcc gatcgcgaac ggcattatcg acaaagagga cgggtattgt
     4261 ggctgaccgg attgcccgga tcaggcaagt cgacactcgc ttttgcactg gagcaggagt
     4321 tgttcctgcg tggacagctc ggttatgtac tggacggaga ccgaatgcgc caggggctga
     4381 atcgagacct tggctttgct ccgcaggatc gccgggagaa tctgcgccgg atcggagaag
     4441 tcgcccgtct gctgcttgat agcggacaga tcgttatcgc cgccctgatc tctcctcatg
     4501 cgcccgaccg gcaaatggtc cgggagatgt tccagccgca ggacttttgc gagatctatg
     4561 tcaactgctc actggaagtg tgtgaacagc gtgatcccaa gggactctat cgccgggccc
     4621 gcagcggcga gattcccgaa tttaccgggg tcagtgctcc ctatgaggta ccggagcagc
     4681 cggagctggt tattaacacc gagttcctgt ctgtcgagga atccgtcatg ctgatcatgg
     4741 agacgctgga actggcaggc atgccaagca tggatgtatc gcgctaatcc aatgactgct
     4801 gaagctgctc ccattcacag ccatataaaa ggatcgatga tggctgatcg accagaagca
     4861 gcttcagctc cagtacagtc tgcggtactc ggtcggggtc atcttttccc gggtcaggaa
     4921 ctgccggtta aaatagctta cactcggata gcccgcatcc tcagcgatct ggccgatatg
     4981 gcggtccggt cgctccagca gccactgctt ggccatctgc aatcgtgaac gggtgacgaa
     5041 ttccagcggc gtcatctcga ctacactttt gaacagacgg cagaaataat gcacactcac
     5101 acctgcccgg tccgcccagt cctgcagcag aaaaggttca caggcttcct gctgcatctg
     5161 cggcagcagg cttaatatcc ggttctccgc ctggccggcc cgtcggttct tcagcggcac
     5221 tgcctgatgg acaaattccg ccagtacggc ataagtcagg gtggataaca gtgccgggtg
     5281 cagcatccgg tgctgctctg cctcttccaa cagagccaga tgcgccatct cccatgcctc
     5341 ccgttgacgc agcgtccaca gcagatgccg gtgaaatccc cgctcgatca tatagtcatg
     5401 cagacgttcc ccatagaaat gaacccagcg cacatcccac ggatcatctt cactgctgta
     5461 atatcgctga cgctgatgcg gaaaatacag caccgcctgg ccgctgcgca gctcatgtac
     5521 cgttccttca acctccacat atcctttccc tgcagctaca taatgaatat tgaagttatt
     5581 cagcgctccc tcttccctca ggacggtatg ttccggctgc tgctggtagt gcccgatcga
     5641 ctccggcaga caaaaatacg gctgttcctg cagggtaagc agtacggtct gtctcatctt
     5701 gcccaccttc cctaatgaca atattgtgtt aaccttattc aatatattat catttccaag
     5761 cgtttttgaa ttcattataa tcacaatata caagtaaaga aatctgctct gcgaaaggaa
     5821 gcgataccaa gtggaatata tccaaattga aggcgcccgc aaaccggtct cccggctgat
     5881 caaaggtacc gactacttca gacatgatac gtacgagaaa gcggcaggca atctggatgc
     5941 ttttctgtcg attggcggca gcacgatcga tactgcccat atttactgcg gtggtgagag
     6001 tgaggaagtg ctgggcaaat acatgcagga gcgcggcaac cgggaatcca tcgtgatact
     6061 gactaagggt gcgcatcatg accagaatgg acctcgtgtg aatgccgaag caattcgcag
     6121 cgatctgctg accagcctgg aacggctgca gaccgactct gtggagctgt atgccctgca
     6181 tcgtgatgat ccatccattg ctgtaggcac tattctggaa gcgcttaacg aacatttgga
     6241 agccgggcgg gtcagagcga ttggagcttc caactggacc tggcagcgtc tgcaggaagc
     6301 gaatgattac gcagcttccc atggactcac cggcttcagc ttcagcagtc cgaaccttag
     6361 tctggccaaa gccaatgaac cattctggcc aggctgcgtc tccgctgatc gtcagatgct
     6421 ggactggcat gaacagacgc agctgccgct gctgtcctgg tcttcccagg ccaggggctt
     6481 ctttaccgga cgcttcaccc cggaagtacg ggacaatgaa gatctggtac gtgtgttcta
     6541 cagcgatgac aactgggagc gcctacaccg ggcggagcag ctggccggac agaagcagac
     6601 gactcccatc cagatcgcgc tcgcctatgt gctcaatcag ccatttccga catgtgcatt
     6661 gatcggcgca cagaatcgtg aggagctgct gtcctgtgat gaaggagccc gcattaccct
     6721 gtcccgtgaa gaagtagact ggctggatct gaaataagga tgaaaagcgt agacgggtta
     6781 taccggatat cgcaaggaaa agccaagcga tcgcttctat atcattttta atttacatgg
     6841 ttatatgcat gtacatgttt atatgcagtc aaaaaaaagg aacagattac actgcatagg
     6901 cagtcatctg ttcctttttg ctattacgat gggtattcaa ctatgactat agcccatgct
     6961 gcacctgcac ttccaggcgg tattactggg cagccgtctg atacgccagc agctggtgga
     7021 acgtgccttt ggtctcgttg gacagctggt tgaatccacc ctgctgtacg atctgaccgt
     7081 gatccatgac gatgacctga tcggcgttgc ggatcgtgga cagacggtga gcgataacga
     7141 tcagtgtgat cttgcctttg agcttctcga gagcgagctg caccttggct tcattctcgg
     7201 tatccagcga gctggtcgct tcatccaaaa tgagcacttc cggcttgcgc agaatggcac
     7261 gggccagcac gatacgctga cgctctcctc cggacaggcg gactccccgg tccccaatga
     7321 ccgtatccag cccacccggg agctgccgaa caaactcctc gcaggcggca aaggacaatg
     7381 cttcccacag ctcgtcctcg ctcgcatccg gcttcacgag cagcagattc tcgcggatac
     7441 tgctgtggaa cagaaacggc tcctgagcga cataaccgat cgaattgcgc caggacaata
     7501 gacgttctcc ggtcagcacc tctccatcta ccgtaacctg gccttcctgc ggctccatca
     7561 gtcccatcag catatcgatc agcgtactct tgcctgctcc cgaacggccg gcgacagcgg
     7621 tcatctgacc tgccggaatg aacaaattaa tattttgaag ggcattgcca tgctcttcgc
     7681 tgtagcggaa cgatacctgc tcacagcgga ttccctgctg cagcggctgg accggtccct
     7741 gaccgtagcc gaccggacga tacgattcct cggcctgttc acattcggcc tgcagcttgg
     7801 acaatgcgcg gaatgcaggc agcagtgcac ctatgtattc cagatacgac tgaatcccgc
     7861 tgaatctcgg ccataaccgg gcaaagatca gcacgatcag caccgaacgc tccggctgca
     7921 gcttgaatac ctgcgcagac aatacgataa agcccacgat aaatacgaca gagatcagct
     7981 tgtagatgag ctgtgttgcc gaattcaggc gaatctgctg aatcaggtta tactccagct
     8041 tgttggccat tttgcggaac cagtcaaaat gcgatgcttc cagcatattg cttttgatat
     8101 ctttgatgcc attcaggttc tcctgaatcc cggagaaata gtcctgcgac agctgggtca
     8161 ttttgtcccc gtaggatttg gatctgcgaa caaatttgcg cgaatacagc gccagcaatc
     8221 cgccgccgat catcaccagc agcgtcattt tgaatgacag taccatggcg aatccgatct
     8281 gaatcacggt aaacagcagc gaagtggaca gcatcagcac cagattggta ccctggctga
     8341 cccgggccag ttcggtagtc agcatatggc tgagatccgc tttgcgcttg cgcaggaaaa
     8401 atgaccagtt ggagcgcata atcgagcgat acacacgcag acgcaggttt ttgataaatc
     8461 cctgctggat ctcggcgccc ataatggcct gcttgcgctg catcagtccc tgcataatcg
     8521 tcagcagact gtagacggac aaaatgataa ttagcgtcgt ggtgaccggc atttgcttga
     8581 gcggttcgaa cagtccggcc atcggcagcg tactgctgcc accaccgccg aatacaccaa
     8641 tcaggctaag cagcggtacc agcatataca gagtgaccat atcgagcaga ctgatgacca
     8701 gcataagccc gatatagaaa tagatccgtt tgccgccata ttgacggagt tcatttacat
     8761 aactgcgaag ctcattcact gtcccacctc ccgctgcagg gcactgcggc gctggttacg
     8821 acggtatagc agcagaaacg ggtgcagcgg ataatacatg aaatgcagcg gcttaggcag
     8881 cggcagtgtc tgcatatccc aggcatccgg tgtcatcttg cgccaccaga acagtgcttt
     8941 ctgtccgttc gtacgcagtg catactggta ggaacggtat ttctgggcaa gctgctcggt
     9001 ctcgggttcc gggcataggc ttaccttctc ccggatgaag acgatgaccc gctgggcaag
     9061 atccttcgcc cgcggccgat tcatcagcgc ttccatctgt ggcgtcaccg gtgtctccag
     9121 cagggaagcc gacagcagga aggcctgtcc gataatatga ctgcatttgt actggcgaac
     9181 aagacggctc agcagctccc aatcgatatc catctggacc agcttgtcca tatcggccag
     9241 ccagcgcagc cggaaccagg catgacgtgc tccatgaaca gcgaggtaga tcagcagatc
     9301 ttccttgcca agcatatgca ccgccgttcc gccaaacgtc agcgtctgtc tgcgtgccca
     9361 cagatcatcg aagctctgct cggcgccggc atccccgttc agccgccagt gcagctcaat
     9421 ctccaccccg gtgcgttcat gggtgtatga ttcatgatta tagcgccatt tccacttatc
     9481 cagcgcacgg tccactgcct gggtcttcgt ataaccaagc tccagcagcg cctgctccgc
     9541 ctcttcgatc cggtccatag gtacgagcac atccagatcc ttggacgtgc ggcgggacag
     9601 atcaccatac agcagctggg ccagtaccgg tcctttgagc tgcagagccg ggatcttctc
     9661 atccgagagc ttctggctga ccttttgcat ctggccgctc agctgcagca tggtaaatgt
     9721 attatgatga tatctgtgat tcagccactg catcgtttcc ttgggcagca gctcgctctg
     9781 ccgggacaga tgcgcatgga tggtcggata gacccggtga tgcatggaca gcgaactgaa
     9841 ctcctgccag tccagcgctg gccccatgcc agccagtaac aggtcagcag gcttatcctt
     9901 cattgaaccc aacatcagtt tcaattcgac agggaagttc cgtagatcaa ggccccattc
     9961 cttattcatg gcttactcct ttattccgta ttcgtaataa tcagttaaat tgcttggcaa
    10021 atcgtccgac aaccgtatac tgctcgattt ccttggcgcc ggttaagtaa aagcgcccgc
    10081 ttctcagcca cgcatgggcg gcattgctgc ctttggcgtc acgacgcatg cccagataga
    10141 gcgtgctcgg cagcttgcgg cgttcaagca ttttcatcgc ggcaaaggcc ataacgagac
    10201 attccgtttc ccagaataca tgcggactaa ccagatgcag cgctttggag atctgtaccg
    10261 cctcacgatg ggcatcccgg tccgactcat acgaggtctc ctgcatgtaa tcaccgagag
    10321 aaggcgatac cttggcaaaa ggacgcatct tcatgatacg cccccaggcc aggtagaaca
    10381 gggcttccag catcagcttg cgcatcgaag ccggatagct gcgcagtttg gctactttgg
    10441 acaatttagc gaacggctgc gccattgacc tcaaccagcc cttcctgcag cattttttct
    10501 acaaatgtgc tcacctgctg cttgcatact tccggttcaa cttcgtattc ctgcaccagt
    10561 acagctacaa tctcatcgac ggtaacagga ttttcgctga tatcccagat tcggcctcca
    10621 atagcgccca gattgtaata tttgccggat tcgatatcca gcatgacttt ttctccattc
    10681 atatcgctgg cgatatagtt ggaattctgg gtaattttct gttcggcatt gatcaggttt
    10741 ttagacatta atggttcccc tttcgctcgt aagctggtat atggtcagac atgggtatct
    10801 cgatataggg taggcttttt atctccttgg cccattcctc tctctgcctt cagccattgc
    10861 tgccggagcg ggatgcggcg tgatttttgg aacggataat gtccaatacc ttgtccataa
    10921 tagccggtgc ggtaaaagca gtcgtggagc gctggatctg gtacgcgtcc agttcccctg
    10981 ccagtgcggc gatctgggag aaatgacgct gcttcagccc caggcgcggc acgatcgcac
    11041 cgcggaacgt atgggccagc ataatatgaa gccgttccag ccggttcagt tccgtaatgc
    11101 tcgcttccgg tgcatcggtc ttcaccagtt caaatacgcc agcgagcggc actggttgat
    11161 tgtaaaagcg gtcgccgacc gggatcgcga atttatcgta ttcatcatgc agggtcgaat
    11221 actgatccga tgacattccg aaatgattca aactctcctg ccacagcttc tgttgcgggt
    11281 aggccggata cacatgcggt actccattct cataattcac ggcaatcaca tcatcggtga
    11341 tcagcggata gccggcctgc ataaatgtag ccgcaagcgt cgacttgccc gctcccgaat
    11401 gaccgacaaa agcatacgct tgaccttcga tcagcagcgc actgccatgc agcgggaaaa
    11461 tgtcacgctg catcagcaga atgcccatgc aggtgcccag tacgaacagg cgcagcttgg
    11521 cttcactgac ctgaggagat ggatcgatca cgatactgct gccttcatga atacagaata
    11581 tgccggtatc cggcatctga aacataaagc ctggaggctg catcgtaaag ttcgtttcac
    11641 gggtagagat tgcttccgcc cattgggata aatccgcaaa gcggacggtc acatcagctg
    11701 atctatttgt attattaact tgctgtagct caggcaagga aatttcgctt ttaattcgca
    11761 gaccaaaggc ttggtatacg gtttgttgga tcgtgttaat agtaataacc tcccgatagg
    11821 ttccttcgcg tatcgcttca ggaacttaat gcacaccggt gattccgtca tgtcaaaatc
    11881 ctgttgaaga aaatggaccc ttatacattt ttgaggtata agggtcactt tgagaattac
    11941 attattgctg gtcttacgaa gcaacacagg ttgcttacca aaaacaatca gcaagactta
    12001 cgcaaatctg catcatttat attcgactcc gtcgatgacc tttcagcctt tacctggcac
    12061 taaatcaatt agctgcctgg attgtacagg tctgcgtcat cataagtgac ccagtcaatt
    12121 gctttccagc ctttacctgc cgcagtttcg ttcatttcca aaacttccag cgctggagct
    12181 tgccattgca ttttttcgtt gttcatcctg tgttcctcct tactcgttaa atagaataat
    12241 ttgctatgga taagatatgg aaatcagctc gggttgtaca ggtccgcatc gtcgtaagta
    12301 acccagtcga tgactctcca acctttacca gctgctgttt gatgcacgtc caaaacttcc
    12361 aaggatggtg cttgccattg cattttttcc tggttcatta ttatttcctc ctcaaatgtt
    12421 ttggattcag gggtgagcct gtcactttaa tggaaatgga ttagctacct gggttgtaca
    12481 ggtcagcatc atcgtaagta acccagtcaa tgactttcca gcctttacca gctgctgttt
    12541 cattgacatc caaaacttcc aacattggag cttgccattg cattttttct tggttcatga
    12601 gtatttcctc ctcaaatgtt ttggatagat tggtcgtgca acttacccct ttaacatgcg
    12661 acaattagct gcccgggttg tacagatcag catcatcgta agtaacccag tcaatgactc
    12721 tccagccttt accagctgca gtctcattca catccaggac ctgcatttcc ggagcttgcc
    12781 attccatttt tgtcatgttc attattcacc tcctttatag ggtatacctt gctatgctaa
    12841 gctgcggata aagcgtccca taatgagact gcgcatcagc aagcgtgtag ccggattaaa
    12901 tgccgcttca gcggttggtg aatctcccac ttccttcaga gcttccataa tattgccggt
    12961 gttcatccac tgcgcagctg ccgggtcctg gcagatctcg cggatctcgc tcgtaaaggc
    13021 aggccacatc ggcagcatac gctgtaccca gtcggcaggc tgcagaccgc gtactttctg
    13081 gttgagcctg atcttgtccg gcaggtctcc ggctgttgca cgccggatga gcgcgcggtc
    13141 cattccattt tgtacatact ggttatatgg aaccgacaga cagaacttga taatccgcgg
    13201 atcgttggtt gggtcgcgtt cccagacgcc gtagcccatt gagatcttgg aggtaactgc
    13261 accatccttg ttggctgtcg ccaggttgga gaacttgcca agacggatat cctggtcgct
    13321 catcgtatcg ctgccaacca gatcgagctc ggctcgtcgt actcgctccg ccatcccggt
    13381 tcgctcagcc agctccggat taatccattt cagcgcatcc ggccgtccca gatcacgggt
    13441 actgcggctc agcttgggaa aagcggactg ctgaatctgc tgaatgatct tcttgcgccg
    13501 tatgccggca ttctggctgt acagcttcat ttcctgatac aggcgaatcc actggaattt
    13561 cttgagcatc tcgccatagt attcaatcgc cggcccccag gagattgtaa agttcccacg
    13621 tgctccggtg agcagtacac ccgctccctg cttctgcgcc tgttcgaaaa taccgcgaat
    13681 ccagaaggaa ttctcaaagt acttgtaagg catctccatt agggaaagcc agtgttccac
    13741 ttcactgagc ggactgcggt cggcaaaatt catgtacgta tcatgcacag gatggatttt
    13801 gctgacatgt ctcacggtct cttcgatata tggccgttca ttggccatga gccgtgagga
    13861 ggtccagtct ttgaagccgg gaatgggcac aaagctgtat gtatgaatcg gcttgttctg
    13921 accggacaga attttcgctg catagctgac gacgctgccg gaatcgagtc caccgctcag
    13981 tgtagctgct atgccgtgac gggtacgaac cttggcccga ataacccgtt caaatacgtc
    14041 gcggaatgct tccacatact cgccatccga cttgagccgc agcagttcat ccggcagcag
    14101 ggttccgtac tggtaaatgg atgatttgtc cgcagacagc accatcgcat gtgccggagg
    14161 cagctgcttg atctgctcgt acacggtcgc ctggatatcg gttgattctt ccatggcgac
    14221 tgtagtcagg aattccgcca tccacggagt ggacaatttc ttgctcacat caccggtctg
    14281 gaacagggct tccatcgtgc tggcaaacat gaatttttct gcggtctggt aatagtagag
    14341 cgtccggtta cctgaccagt ctctggccag aaacagctgc tgtctggatt cgtcccagat
    14401 cgcaaaagcg aagtcaccgt tcagataacg cggcatctgc tcgccccatt tatcgtaggc
    14461 atgcagcagc agcataatat ccggcatatc gatcatggaa gcattcaatc ccagctggcc
    14521 gaacagctct tcacgattgt cgataatgac atcgcccgtg atcgccatcc gccgaaccgc
    14581 atcataatag ggcacctgct gattcaccgc ttccggtgtc acccactggt catggcagcc
    14641 gaggaaaaga tgttctccct gccatactac cgaagcatca gcaggatatt tctccatact
    14701 ctgcatcata cgattgccct gctgctgcag ctcctcgctg ttatgccgtc cggccatgtc
    14761 ccagattcca gctgttgcac tcatgcctgc accccctttg gtgattagtt atttcgatat
    14821 ctgtgtattt ataaatcatc tattatttat taatgaacag ctctgttatc aggctgtata
    14881 tatatgatgt ccgctgatgc cttaatgcag acaagaagct gtcggtattt cgcgcagcag
    14941 ctgttcgctg tactgcttga gctgatcacg ctgctctctg taatggagca gacgcagttg
    15001 atgatgctca atgaaagaga taacctgata tgcctctgtc tccgataatg cacaggatgg
    15061 atacctgcat gcagcagtat taatcgtgtg atccggctct ccggcagtaa gggttgggga
    15121 accatccgat tgctgcgcac gaattaaccg tttattcact aacttagttt tgccatccgc
    15181 agttaccatt tgttttctcc tcctgtccac tctctatccg ctgcgaacat ttacatccgc
    15241 tgtcagacct gaaccgttta cgggaaaacg tatatccatc tcttcataca acaaccattg
    15301 gatgaatcgg ttattgaaca agtagcaggg ccggtaattg atcgacaagc aaatttgctc
    15361 attgttacct ttacccaatt gttattcgtt ttgaataact ttattgattt gtaacatatt
    15421 atatactcta atcgaataat ttacatgata aattttccaa ttactaagat aaattatttt
    15481 tttcgttaaa tgcataaatg ccgaaagtcc tagtacagct tagattctca tcttacattt
    15541 atggtatttt aagtaaaagt aattatctaa acccttataa cataagggta tttgctaact
    15601 tataatcatg gtctattgtt ccttttttat tttcataaac tttggtagta ggaaaatagt
    15661 aagcgtttta ttttattaca attttgttac aaaagatatt ttattgtaat aatttatgct
    15721 atttattcca acataagatc gtatgttcta tttatatacc taattaaaat atttcaaaat
    15781 ttggctatct gaccaggctt tccttattct tttgcatttt gctcacttct tatgtaagct
    15841 ttgcctttaa tctcattttt ttctacttcc atatccacat cttcaaacgg gacatccatt
    15901 tactttttta agtattcttg tcataaaaaa gaacaggccg tagttatggc ctgctctcga
    15961 aacctgaatt ttgattttta aggcaggact tctcctcttg cgcttacata cagactatac
    16021 cattcttccc gggtcatcag ctcggattgg cgttcggcat cctgacaggc ttgaatccgc
    16081 tgcggattgg ccgtaccgat aatcggctga atcatcgccg gatggcgcat cagccagccg
    16141 agcacaatcg cttcgggagt tgtctccttc tcatccgcca gctgctgtac gagccgggca
    16201 gtcgcctgga tatgctcggg ttctttgtcc acattgcgac cggagaattt gccctgtgcg
    16261 agcggccccc acgcctgaag ctgaatatgc tgtgtgcggc agtactccat cagtccctct
    16321 gcaaagttga ctgacgtgcc ggccgcctga ttcacatgta caacctgatc gacaaagtgc
    16381 agatgtccca gactcatctc cagctgattc actgcaaagg aatccggtat cgcctgctgc
    16441 aggaaagcga tctgtgcagc actcatattg gatacgccaa aatagcgtac tttaccggaa
    16501 gccttgagcg cagcaaaagc ttcagcgacc tcttccggtt ccaccagcgg atccgggcga
    16561 tgcagcagca gtacatccag atactcggtg cccaggcgct ccagactgcc atcgaccgaa
    16621 ttcagaatat gttcccgcga gaaattaaag cggccaggca gttcatcgtc ctgcagctga
    16681 atcccgcatt tggactggat aacgatctgt tcacgcagtt ccggacggtt atgcagcaca
    16741 cggccgaata cctgctcggc cttacctttt gtataaatat ccgcatgatc gaacatggta
    16801 atgccgatcg acagtgcagc atccaccgca gcttccgctt ccttaacatg ctcatcggta
    16861 aatggcgtcc gatcccagcc gcctccaaaa ggcatacatc ccagggccag acggctattt
    16921 gaaattccgc gctgggccag tggcataatc ttggtcattg tatttcctcc tgtctatgat
    16981 agcgctctta ttccatccta tattctcata attccatcgg tgagcacaag ctatcgtatc
    17041 attacccata aaactggcag acagggcgtc tccttctaaa ataaacccat accactcccc
    17101 gacaagtcac cgactggtgc gcaaccaaaa aaggagcagc ctctgcatag gctgctcctt
    17161 cttacaaacg tacttgtagc atctcatatt ccgtatttcc attttcgcac tttatattat
    17221 agagggaacg gcacactgac tgccacagtt ctctacctct accttcactt tttattgata
    17281 caattcaaat tcatttacca caacctgagt aggaccggaa ttgcggttaa tgatcagttt
    17341 gtatgctttg taagcactat cgttgtctac agcgtagatt ttcttttggc ctggctccca
    17401 acgcatggag gatttcactt catgaatgac ttcttcccac tctttgccat cattggagcc
    17461 tacgagcatc caggataccg gagccgtcgg tttgctggtt accgctattg cataaccttt
    17521 gatcactttt gggctggaga acgtataggt cagggatgca tccacataac gctgtgaatc
    17581 ggatgtccag acactgtcac tgctcagcgt atgatcaaac gctttccagg cggactctgc
    17641 attgaccgat gccgtagctg tatcgccggc tgccatagtt gtgttaccgg gcgtcggtga
    17701 tggagcactc attgccggga ttatattggt atttccatca aactgtgcca gttccaggtc
    17761 attgattcct acccatttgc tgccgttgtt gccggtgatg aacagtgcat aaccggagta
    17821 agcaacatca ttatccactt caaaggtacg tttctcacct ggtgcccagc cgctttgatt
    17881 ggactgctca tcgatcacga gccagttgct gccgattttg ccggcgaact gccatttttt
    17941 cggtgcgtct gctgcatcat acgtatctgc ctgtactgta tatttattga caacctgctt
    18001 ctgggtcagt tcgtaagaca ggctggacat gccgcctgcc ggtgctctcc agtagctgtc
    18061 gtcggtttcg ttattgtcaa aagctctcca ggcttcatag cctgtttctt ctacactggc
    18121 tttggctgta ccattgctgc caacactgct gcttagtgtt ggtacgatat ccccaccgta
    18181 ttgcaatgca tgcactgttc caccttgaaa gacagtcccc agaaacaatg cgccagccag
    18241 taccattcca tttttaaaag taagcaatcc cattttaaat ctctcctttt gaattcaatc
    18301 gttctttata tttgtggtaa agcggatggg atagctttct gtagaagagc aatacatcat
    18361 cgagtaccaa ttacagttcc actcccatag aaccgtctga gtctgaagat tgatgatact
    18421 gtctacatcc atttctcccc aaaaaatgaa tgaatatttc cctgacggtt aaataaccat
    18481 attttagatt gttgactcac ttgattacat attattttat aattttccaa tttattttta
    18541 ctttttttga atccctgctt tttcgccttc aagcagggca gtctcctcct tccatgcaaa
    18601 gtttccagaa aatacgggtt tcacagttgt taggtgcact ggagagaact atgtagaagt
    18661 ctctgcccat caatagagga caattcttac tgcgatccct atatatttct aataaaaagt
    18721 atttatggat aaattctaca tccatctact caaattgaga tgatgcgaat tgctcattta
    18781 tcttttttta cgttttttgc ctttaaatga cggaatatgg ccgaatatca ggtgttttta
    18841 ttcgctattt cctccttatt ttctttacga tgcttttcat atgacttttt tcgacatgta
    18901 atatgcattt ttatgtaaaa attcatataa gaaaaaggac caatccgccc agggatatgg
    18961 tccttttctt tattattata tggttttgca taaatgtgaa cttatttacg gtgtacagta
    19021 aagccatttc cttcggaagt cacggttgca cccaggattc cagctaccga acgcaggggt
    19081 acatagacct tgcctttgac attaatcact ttggaagaca gtgtctgggt ctgtccatcc
    19141 actaccgcct ggttggagtt cagcttcagt acagttaccg cgccagtaat atcgtcggtc
    19201 agggtgagct gcttggcgga ggcattccat tccattttgg catccagcgc ttcagccaga
    19261 tccttggccg gaaccagggt tacacggttg cgggtaataa tatcgtcatg gtcgccatag
    19321 tctccgaaat aagccgtttt ctcggtaatg ccattcatgt tgttcagcag catgtacagt
    19381 ggagatgtct cttcaaagtt acgcaggaac gtacctggcg tagtcttctc ggacacctgc
    19441 agtacgccgc ctgcagtatc taccggatcg gcagtaacgt taccgttgat attccacgat
    19501 tcacttgctg tcgtaatacg gatcgagcta aatggtgtat attccgtatc cggcagtgca
    19561 atcgtcaact ccatggactg cttgcggata tacatgtcct tgtcaaaata cacatcggtg
    19621 ctgacacggg tattcggacc gaatacggta ttgaattcag gcgattcctg cagctcagcc
    19681 agctggctgt catattcttt gagagcgagt gtgagcattt tgctgatttc cttgtatccg
    19741 ttatttacaa atttctctct gctgcccatc gaatccagcg atgattggtc accggctttt
    19801 ttgagagtag aggccataaa gtcatagaag gtaccgatca gctgacgcat tccctgctca
    19861 tcctgcgaga tgctgctcag aaacggttta acgagtgtga ttaattcctg tcctgtcagc
    19921 tctacatgca gctgggtcag atcaagattc tcaccatata cctcctgctg tacggaactc
    19981 accgagatat cggatgggtt cggcagatga gtgtacagga aagagataat ctgtttggca
    20041 aattcctgtt cttctccctg gagggaagtg gtggcaaagc tgccgctcag cccggacaag
    20101 ccggtcatcg aatcattaag ggcaaaagat atgtatattg gctgtttggc gccctgcaga
    20161 tcgatggtca ttcctttgtc atccagatag aggtgatatg gcagttgttg tccgctgtat
    20221 tgtacggcac cttttacgga gatcttgccg tctgcctgaa gtttggcact gtcaatattc
    20281 agctgcagcg aattcaggat ggtagccatc ttgatgtcat ctgcactggc tgtactggaa
    20341 ggtgtcaact gaaccgacag cgtctgactg gattccattg atttgacatc cagattgcgg
    20401 atcatggcat ttttgatatc cagattccca accgcctgac aaccggacag tacgattaac
    20461 aacagtacca gtggaagcgt aatccataat ttccttttca tgattaatcc cctttcgtat
    20521 tcggaattcc tttccattat cccagcttgc caaccatttg taaaataaca ctgtaatttt
    20581 atgtaaatat ggatgtataa tatttagcta tccgtactgc ttgctgtgcc ttgcgggaga
    20641 gcgaatatgg tacaatacag cctgatagct ggtgcagctg ataataaggc aagatcaata
    20701 gacaagctgg aggaatcatc catgataaaa aatgaaaaga tcaaagcatc cgaagtgcat
    20761 ctgaccggcc tgaacggtga agatctcggg attatgccga cgaacgaagc gctgcagatg
    20821 gctaagcagc taaaggtcga tttggtatgc aattcgctat tcagcagccc gccgccctgt
    20881 cagctgatcg ctgccggagc cgccaaacag aacaaacagc aggctgccaa aagcgaccgc
    20941 ccggccaagg tcaaagaaat tcgtcttact gccaatatcg aagatcatga ttatgaaacc
    21001 aagaaaaatc aggcactgcg catcctgcaa tccggcaatg ctgtcctgct cgtcgtcaaa
    21061 acccagggca gcaaggaagc cgccaaagcc aaatcgatta tcgaagacct gctccgcgat
    21121 ctcaaggaag tcggcaaacc acagaccggc attcaggtca gcggcaaaca atccatggta
    21181 caggtcgatc cggtataact tcgtaacgtt ataacgccaa aaaagacata caaaaagagg
    21241 agcacccgaa tgatcgcggg gtgctcctct ttttatctct tatccatccg tttgctgcca
    21301 cattagattc cgtctctgat ccttacagct gcggatcact gaccgggcgc cgcaagcgga
    21361 taatggccgc actctcctgc agcacccgct gcagctcgga acccataatc ggtttgctga
    21421 caaaattatg catgcctgca gccaggcagc gctctctgtc ttcatgacgg gcaaatgctg
    21481 ttactccaat aatcagaggg gtctgttcat ccgtaaaatg attccggatt acttcggaag
    21541 cttccagtcc gttcatgccc ggcatctgta catccataaa gatcagatca tacgtcctag
    21601 tcatgcaggc ctgtaccgcc tcttccccgt tcatgaccag atctgccgta tagccttccc
    21661 gctgcagcat ggatagcaga acccgctgat tggacggatg atcttcggca atcaatatgc
    21721 gcagctccgg catatccgcc gccatactgg cgacagctgc cctggcagtc tgaccgccgg
    21781 catgaatact caccgactgc tgttcatccg atttctcctg ctgatcggcg gtgacgctgc
    21841 ccagcttgag tacgaatcgg aacatcgcac cctggttctc ctcgctgatg acgccgatgc
    21901 tgccatccat cagctccacc agctttttgc aaatggataa tccaagcccg gtgccgccat
    21961 acttgcggtt ccagaccgga tgcagctggg agaacggctg gaacagcaga tgctgctgat
    22021 gaagagcaat gccaataccg gtatcctgta cagcaaattc aagccagatt tcctcgggat
    22081 tatcactttg tccctcagag cgctccagcg cacgaaccga taccttgatc tgtccctgct
    22141 cggtgaattt cactgcattc cctaccagat tgatcagaat ctggcgaatt cgtccggaat
    22201 cgccgaccag cacttccggt acttcgggag caatctcgac agtgagttcg gtccccttct
    22261 cggaagctct catcaggaac agatctgcaa cagaatcgag tactctcgat gcctcgaacg
    22321 gttctggttc cagtgtcagc atgccggctt cggccttgct gaagtccagt atttcattga
    22381 gcagctgcag cagcgtttca ctgctgttca ttacaatttc cagatagctg cgctgctgct
    22441 catccagctc cgtatcggcc aacagaccgg tcatgcccat aataccgttc atcggtgtac
    22501 gcagctcatg gctcatcacg gacaggaatt ccgatttggc ccggtctgcc ttttcggcgg
    22561 attccttggc acgcagaatc tccttctcat ccgtaatatc ccggaagacg ataaccgtcc
    22621 cgcgatattc gccctgctcg tacaccggtg tcacccgata agtggcaagg aagctcgaac
    22681 cgtcgttttt ccaaaaaatt gtctcctgtg cctgatgagg ggacccctgc ttgatcgcct
    22741 ggataatcgc cgattgttca ttcaggatgt ccacatcata gagcgcctga ttccagccat
    22801 gagcattata aagaccctgc ccttcctgct gatgcatcgt cagccccagc atttccgcac
    22861 cggcccggtt gatgaaaatg ccgtgacctt ccgcatccac actgaatatg ccttccgaga
    22921 ccgaatcgag gatgagcgca cgttcattgc ccagcttctc gatctggctg atatactgct
    22981 tgagcttggt tgtctcggta ataataccgt acaatccgat aacctcggta tccgccataa
    23041 tcggcacatt gataacgtcc gccgggaaaa aggaaccgtc tttgcgcggc accgaaatct
    23101 cgtacgtctg cggaacaccg cgcgccgcca tccgggcgtg atgagtgatt ttgtccaggt
    23161 cctccgccga gaagaagctg aaaatccggc gtccgatcaa ttcatgacgg gagaagccgg
    23221 taatctcctc cagactactg ttgaccgaca ggaaatgtcc tttgagatcc attgcacata
    23281 cgcccgatgg attgttctca aataaggaac ggtagcgata ttcactgtca cgcagcacca
    23341 tttccagata tttgcgctcc gtaatatcac gggagacaga ggtgtaaccg tagctgcctt
    23401 cctgctcgtt ataggcgtac cggctgaccg tctcgaacca gatataatgg ccctttttgt
    23461 gccgatagcg gaagatgatc gtatcatgct ggctgccttt gcctttgatt tcttcgagga
    23521 agcagcgtgc cttgtcgaca tcttccgggt gcaggagttc atagcatgaa cgaccgatca
    23581 gctcttcggg ttcataaccg agaataatca tgctggccgg tgatacataa cggaacgtga
    23641 attcctgatc atcataatgc cgggaaatca tatcgagtga attttccgtg atcagacggt
    23701 aattatgctc actctgccgg agctgctcac tcatctgatg gccggcggtt acgtcctgca
    23761 cgatgccgat aatttgcagc ggctggccgc tgactttgtc ggtaatcact tcccagtaag
    23821 cctgcacgac tttttgtata tcaccgggca gtacaatccg gtaaagggct tctccactgg
    23881 taccgtcacg aaccgcatcc agaatacatt tcatgacccg ttcggcatcg tccggatgaa
    23941 tggtggacat atacgaatcg gtattcagct ccaccggttt cattacattg ccaaagatcc
    24001 gccggatgtc tctggagaaa tgaatccgat tattgaccat atcccaatcc caggcaccga
    24061 tctgggccag tttgtgggca cgggagataa tatcttcctg ggctttgcgc ttggttacat
    24121 cctgcgcaat actgagaatt cgctccactt cgccgcttgc attatgcatc gtctgggtaa
    24181 agacctcgat ccacagataa tgcccttctt tatgtctggc ccggcgaata aatgttttgc
    24241 tgtcattata catatggccc ggcttgagca tatcctgggc gtcctgctca tggtaatact
    24301 ccatccgctt ggaattcata acttcatacg gctcgtagcc gagcactttt ttgatcgaag
    24361 gcgatacgta gttgatcgta ccgtccggca agctgaccga tatcatactg gatgaattgc
    24421 gagcgaccat cgtatacagg tcttcctctt cccgatcggc aatttcactg gcatagagca
    24481 ccagatactc catatcctgc tccggtacat ccggatagcg cgacacttgc agggataacc
    24541 agatcgtatt ctggtcgcgc cgcatcagac gccgctccaa tatgtcgttc tgctgctgat
    24601 acagccagct gtccgccagc ttctgtatat tcaaaaactg cttcagctcg tcctcttcat
    24661 aatccagtaa ccggcaaaaa gcgggattga cctgcagaca ttcaccctga ggcgagaaga
    24721 ctgcaatccc ttgcggggta tgcttgtata catgcgctag taaggacatg cctggtgcag
    24781 atga
//
