LOCUS       NZ_CP014241            23111 bp    DNA     circular CON 03-MAR-2024
DEFINITION  Bifidobacterium angulatum strain GT102 chromosome, complete genome.
ACCESSION   NZ_CP014241
VERSION     NZ_CP014241.1
KEYWORDS    RefSeq.
SOURCE      Bifidobacterium angulatum
  ORGANISM  Bifidobacterium angulatum
            Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
            Bifidobacteriaceae; Bifidobacterium.
REFERENCE   1  (bases 1 to 2064639)
  AUTHORS   Dyachkova,M.S., Klimina,K.M., Kovtun,A.S., Zakharevich,N.V.,
            Nezametdinova,V.Z., Averina,O.V. and Danilenko,V.N.
  TITLE     Draft Genome Sequences of Bifidobacterium angulatum GT102 and
            Bifidobacterium adolescentis 150: Focusing on the Genes Potentially
            Involved in the Gut-Brain Axis
  JOURNAL   Genome Announc 3 (4), e00709-15 (2015)
   PUBMED   26139716
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2064639)
  AUTHORS   Zakharevich,N.V., Averina,O.V., Nezametdinova,V.Z., Dyachkova,M.S.,
            Kovtun,A.S. and Danilenko,V.N.
  TITLE     Complete Genome Sequence of Bifidobacterium angulatum GT102:
            potential genes and systems to communication with host and bacteria
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 2064639)
  AUTHORS   Danilenko,V.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-FEB-2016) RAS, Vavilov Institute of General Genetics,
            Gubkina, Moscow 119991, Russian Federation
REFERENCE   4  (bases 1 to 2064639)
  AUTHORS   Danilenko,V.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2015) RAS, Vavilov Institute of General Genetics,
            Gubkina str., 3, Moscow 119991, Russian Federation
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: GS de novo assembler v. 3.0
            Genome Coverage                   :: 34x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 08:42:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,676
            CDSs (total)                      :: 1,608
            Genes (coding)                    :: 1,582
            CDSs (with protein)               :: 1,582
            Genes (RNA)                       :: 68
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 26
            CDSs (without protein)            :: 26
            Pseudo Genes (ambiguous residues) :: 0 of 26
            Pseudo Genes (frameshifted)       :: 7 of 26
            Pseudo Genes (incomplete)         :: 19 of 26
            Pseudo Genes (internal stop)      :: 4 of 26
            Pseudo Genes (multiple problems)  :: 3 of 26
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:36:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1953268
            Orig. end                         :: 1976379
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014241.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23111
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23111
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23111
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13111](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13111)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(68..1534)
                     /locus_tag="Bang102_RS07870"
                     /old_locus_tag="Bang102_007870"
     CDS             complement(68..1534)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826882.1"
                     /locus_tag="Bang102_RS07870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007870"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_145885918.1"
                     /transl_table=11
                     /translation="MGVGVSARNWGWRHASRKDFALRHVDFDIRPGERVLLLGASGAGK
                     STLMAGLAGVLGGDDDGEQEGTLLVGGGDARKARGVSGLVLQDPDAQTILERVGDDVAF
                     GCENLGLPKDEIWQRARESLDIVGLDYMRFDHSTRKLSGGQRQRLALAGVLAMHPGLLL
                     LDEPTANLDPDGVKEVHDAVKHVVERTGETLIVVEHHIDVWLDTVDRVIVLGKPDGNSL
                     TGGVIADGTPGEVFGTMGDVLAEGGAWVPGRAITPYHPERSAGEVVLRTDDLSFGREFP
                     LGKHIDLEFHAGEVTALTGRNGVGKSTLALTLAGLLEPFAGHVRMAERMVPPHRANDVS
                     TWKSRDLLGRVGMVFQEPEHQFVTASVRDEVAVGPKSMGKTDEEAYRIADEILERMNLK
                     RFGPANPFTLSGGEKRRLSVASMMAAAPKVVVMDEPTFGQDFTTWTEMVRLIADVRDAG
                     SAVIMVTHDEALIEALDARRIVVSEEEQHD"
     gene            complement(1736..2368)
                     /locus_tag="Bang102_RS07875"
                     /old_locus_tag="Bang102_007875"
     CDS             complement(1736..2368)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826883.1"
                     /locus_tag="Bang102_RS07875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007875"
                     /product="ECF transporter S component"
                     /protein_id="WP_045920233.1"
                     /transl_table=11
                     /translation="MTEPTIDAVENESSAVRKHSNTWRVVDIVVAAIIAVASGVIFWGW
                     DIVCAAPLAIFGAVTPGFEGLLNAFWLFAGPLAAIIVRKPGAALFAETLAAALELTMGN
                     QWGVGGSLIVGIMQGIGAEIGFAIFAYKKWNMLTTAVSGALAGVGCGIYYWVMNPAWGV
                     MRSSIYLGTSIVSGVVLAGVVMYLLHRAIAQTGVLDRFESGRAQTLV"
     CDS             2373..2612
                     /gene="allorf_1955641_1955880"
                     /locus_tag="allorf_1955641_1955880"
                     /protein_id="allorf_1955641_1955880"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPFSHSRHGKRDVRAPELPGKRSYGRSVRFLSASRLPCHCPIIRS
                     TLDFPSSLPRASAAVGAERAGACSFNPRKCSRMA"
     CDS_motif       2373..2558
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MPFSHSRHGKRDVRAPELPGKRSYGRSVRFLSASRLPCHCPIIRSTLDFPSSLPRASAA
                     VGA"
                     /locus_tag="allorf_1955641_1955880_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2559..2612
                     /prepeptide="core"
                     /locus_tag="allorf_1955641_1955880_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.90"
                     /molecular_weight="1848.1"
                     /monoisotopic_mass="1846.9"
                     /core_sequence="ERAGACSFNPRKCSRMA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPFSHSRHGKRDVRAPELPGKRSYGRSVRFLSASRLPCHCP
                     IIRSTLDFPSSLPRASAAVGA"
                     /leader_location="[2372:2558](+)"
     regulatory      complement(2392..2494)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(2452..2463)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     CDS             2483..2602
                     /gene="allorf_1955751_1955870"
                     /locus_tag="allorf_1955751_1955870"
                     /protein_id="allorf_1955751_1955870"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSLPDNTQHARFPVFASTSIGGCRRRTRGSMLLQSPEML"
     CDS_motif       2483..2548
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSLPDNTQHARFPVFASTSIGG"
                     /locus_tag="allorf_1955751_1955870_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2549..2602
                     /prepeptide="core"
                     /locus_tag="allorf_1955751_1955870_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.20"
                     /molecular_weight="1980.4"
                     /monoisotopic_mass="1979.0"
                     /core_sequence="CRRRTRGSMLLQSPEML"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSLPDNTQHARFPVFASTSIGG"
                     /leader_location="[2482:2548](+)"
                     /alternative_weights="1998.4"
                     /alternative_weights="2016.4"
     gene            2710..3705
                     /locus_tag="Bang102_RS07880"
                     /old_locus_tag="Bang102_007880"
     CDS             2710..3705
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826884.1"
                     /locus_tag="Bang102_RS07880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007880"
                     /product="cation transporter"
                     /protein_id="WP_045920341.1"
                     /transl_table=11
                     /translation="MGQTNGGNTKPAHAGSAVKAALAANVGVACAKFAAAAFTGSSSMF
                     SESVHSVADCANEIVLMFGDRASDRKSKGDHPFGMHRAKYLASFIVATLLFFVGGVFAV
                     SQATKKLIGLLDGSVDRQVDSLELLAALAVVVISACLEGYGLHTSIKEARERMDRVKVE
                     KDSLIGFWKRTKSAELASVMMEDTLALIGLLFAGLGIGCSMLTGDELYDTIGGLMVGLV
                     LVIGSAALAFKSGSLLLGEDVDPRTHKLLSQAVNNTPGVERLINMQAIHMDEDAVLLCL
                     KVQTSKLDRDYDVETVDKIEKNIRVALPWYEWEIYVEPDIWRANHVSAEE"
     gene            3874..5019
                     /locus_tag="Bang102_RS07885"
                     /old_locus_tag="Bang102_007885"
     CDS             3874..5019
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826886.1"
                     /locus_tag="Bang102_RS07885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007885"
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="WP_045920232.1"
                     /transl_table=11
                     /translation="MNDIHTIEANIFERLSHVIDPELGRSVTDLGMITSIEAVPSGTVD
                     ENGDGIIDVTVHVELTVKDCPLSETITNQINGTVRSYVAPGSPNVTLVPHIEVSSMPQD
                     KLTSLVQTLKAERRQNPFSKPGIKTRIFAIASGKGGVGKSSVTANLAATFAALGYDTAA
                     IDADIYGFSLPRLFGVHTQPTNLNGMLMPVTAWGVKLISIGMFAGADRAILWRGPRLQR
                     SLEQFLSDVWWGEPDVLLLDLAPGTGDMAISVAQALPNAELVVVTTPQPSASDIAVRSG
                     LVALQVPMKVRGVVENMSYYEHKSEKLRIFGEGGGQRVSEQLTAALGHDVPLMAQLPLM
                     PELRETGEEGRPAVLTPEGALANTPLADEFTSLARQLMELH"
     CDS             complement(5046..5219)
                     /gene="allorf_1958314_1958487"
                     /locus_tag="allorf_1958314_1958487"
                     /protein_id="allorf_1958314_1958487"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRYRQSQRCAFMEGGRFGRYRAVGGSFGRNQADECRFGRNWARKR
                     PNRHPTSGKRPN"
     CDS_motif       complement(5175..5219)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRYRQSQRCAFMEGG"
                     /locus_tag="allorf_1958314_1958487_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5046..5174)
                     /prepeptide="core"
                     /locus_tag="allorf_1958314_1958487_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.50"
                     /molecular_weight="4863.4"
                     /monoisotopic_mass="4860.5"
                     /core_sequence="RFGRYRAVGGSFGRNQADECRFGRNWARKRPNRHPTSGKRPN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRYRQSQRCAFMEGG"
                     /leader_location="[5174:5219](-)"
                     /alternative_weights="4881.4"
                     /alternative_weights="4899.4"
     gene            5238..6047
                     /locus_tag="Bang102_RS07890"
                     /old_locus_tag="Bang102_007890"
     CDS             5238..6047
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826888.1"
                     /locus_tag="Bang102_RS07890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007890"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_045920231.1"
                     /transl_table=11
                     /translation="MRIAIAQFAVDREPDRNIETIRTYAMQASANNARVLLLPEGIIAR
                     DATDPYYPAHHAQPIDGPFVAALRAISAQTGIALMGTVHVINPETPKPSNVFLVIDNGE
                     IRLAYRKIHLYDAFGERESDVIEPGNEVPPLITIDGWRFGVMTCYDLRFPELARAHAIA
                     GADVLVVSAAWARGADKVDHWTTLCKARALENTCYLMACSEHSAHNIGHSMAVDPLAHV
                     IAQSESDDIVFADFDRDTLDKARQTLPVLRNRRFTAPVLQGATRTTD"
     gene            complement(6217..8502)
                     /locus_tag="Bang102_RS07895"
                     /old_locus_tag="Bang102_007895"
     CDS             complement(6217..8502)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="Bang102_RS07895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007895"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_045920230.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.9e-27, bitscore:
                     91.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGHLRIPLVEQGEHSECGLAACAMILKAYGRDSGLEDLRNAYGV
                     PRGGLSIKNIVTILNDYGVTNRAVAVRNIDGFKKLDSPSILLWNHHHFVVLSHYAFGRF
                     YIIDPASGRSSVREEDFRRHCSSAAVLTERAGEKRSIRGAWRDSNCMGVIKDFLVSSPV
                     FVLSAIVLSLAIQSLGLIPPTGMRFIVNRRQLCTSEGFLLAAFVMMLVSFALYYLISML
                     NGLANARLRIGFGNFLFRKYMRGVFEREFAFFINRTSGDMIYRANLVAVVEQMLATGMI
                     GSLVSFVFLAVYLVMMINYSPQLTMVTLAICFVILMVSTIYAAKSKKLVDKETAAQSAV
                     QQSFIEIFSGIETVKSMNLEGFFYRRWSDLLQKQLHFQWKRGKLDAWMSSLSAALEFVL
                     PLAIILCGSVLLAQDMVDLGTVVGFVTLASSFVVPFGSIMTSIGQFAAVLSYIRKIADI
                     IPSGKRTNDGHMDYEMRHVDGEHAPLQRVLPSDSQSGKEITGIGESQENPSCYAAPHSE
                     RIDNYGRESLTAHNVSFSYTVFSKPVVEDITLHIPKGRKVVIVGPTGSGKSTVLKLLSG
                     LIRPTQGRVMVDGHSCEELPLSWRAKNIAFVHQDTTVFNMTLRENILLRRTSVDESRLR
                     QVCKDCCIDESMMNPGLGLDTMISEHGLNLSGGQRQKIAIARAMVTNPMFMVMDEPTSA
                     LDNVTENKIMRALMRAPYACVVVAHRLSSIRMFDEIYVMDDGHIVEHGSHESLMAEGKL
                     YAKLYRQH"
     gene            complement(8521..9264)
                     /locus_tag="Bang102_RS07900"
                     /old_locus_tag="Bang102_007900"
     CDS             complement(8521..9264)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826891.1"
                     /locus_tag="Bang102_RS07900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007900"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_045920229.1"
                     /transl_table=11
                     /translation="MNTTDIIRVNDLTFGYKRKQAVLEHITFAVPKGQSLAILGYNGVG
                     KTTLFDLIVGLRRPWSGYAAINKAFVPSIRDVFQMTEQGGLIDTMTVRENFKFRKMLFK
                     PKDDDKTFFEALEKNPLVRAFELNDQLDKKVSDLSSGLRKRVGIVAGMMFDPHVIMLDE
                     PTNAIDPLTRDLLIEYMGRLRADNRTILTITHDLHYCWNVSDRIIVLDHKHIALDAMLS
                     DFNSFDEFSKAAMLGKEHEHVDFGL"
     gene            complement(9276..10001)
                     /locus_tag="Bang102_RS07905"
                     /old_locus_tag="Bang102_007905"
     CDS             complement(9276..10001)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826893.1"
                     /locus_tag="Bang102_RS07905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007905"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_045920228.1"
                     /transl_table=11
                     /translation="MYRIFAYCGSRNPQSRTLQAIVLIKQWLSSLQDSIDTQISWTICT
                     PKDLRILPSDGTAQEFSTGVDRQELLGIDDSGRLKTMIEHCDYLILGSPTYGHNVSGDM
                     KIVMDRLCYWSHLFYLSGKPGMPLVSASTNGYLKVGDMLERFMDSLGIVRDPTAYNTYG
                     MPFENNEAQGAARHILSALTSHEASMPNGYQEELFHSYKRSYIRRDEQNAEYRYWKKHR
                     MFDCDSLAEYFASLPQVEH"
     gene            complement(10001..13111)
                     /locus_tag="Bang102_RS07910"
                     /old_locus_tag="Bang102_007910"
     CDS             complement(10001..13111)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="Bang102_RS07910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007910"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_052946496.1"
                     /sec_met_domain="DUF4135 (E-value: 9.4e-92, bitscore:
                     304.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.3e-37, bitscore:
                     126.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIVKSMYADTIEERYSLIDDDDASGDDSFVDSVISQWMSRNCAL
                     RPDDFASMLELRGYDKKKYAKCIDGKSFLKGNKGNLSSWYSDFEKIFAFFSNSKFVEDI
                     NVGYVNIFMPFILYAEKTLRTTIPDSQMNSYDNVQNSIRGTLANRLLNIGLKTLVLEMR
                     RENADGNLQGADGHERMLSFIHMASTYAYQRLLYSRYPVLARMLTQATTDYIAFIREMF
                     TRLEESDSELKMFLKSTVPLVLSDIRLDGGDAHNHGRTVAILEFNNGSRVVYKPRDLSI
                     HVLFADLAHECERSDDFLPLHVSRVLPEDGYAFEEFVRQSQCLTCDQVSRYYLRIGELL
                     ALVWFLHGNDMHYENIISDGEYPQIIDYETVCSNYVEMDSQNSLRETADVKVARRLRDS
                     LAGTSFLPTRMVLNTEGESIDFSALNVKDQEVPTLFPVPVMLDTDGACFQKQHVVFSKK
                     DNVLHYNDDVVNPSDYAHEILDGFTHGVHALDRISDDALCRILQRGKATVRVLVRATSV
                     YARFLNYMHHPKVLDDMTKVEAILENLYVFPYKNKHIFLSEYQQMIHGDIPMFVTSLDS
                     KILRDGEGRECGPSFAYSAIERIMRTKRHLHEEARLQESLIRNAFHMLVRQRPAISSSI
                     NEWPLMIGHYLVDQAILSDDGSTVSWICTKQSGESENDANAVGVPSPDLYDGCGGTAIF
                     LASLSQAFGDRRCADYALKTMRSIQLRTSPSASESAFTGGLSQIYPALMLRSLGIKSDI
                     LTNSALQIMDRLERYVKDESVRLSKVGKANRFTYRMDYLAGASSVIILYLRIWELLRDD
                     DILIQLSQLGRIVAKTACRLQREENANSDDSFPAGAGHGLEGISVALWRLYAAVGDTEF
                     ADDAQKIWEKAMAKHKAQPVRSSRERGKWCRGTVGLLWAQNEIDRCTAYGRRFFDDAGK
                     PFPEFSSVKQLIDSCDWVDDSLCHGRSGAIDVLVSLARNTNDERYSALARHLMDDMVAA
                     ASCNKHFDFGKVSAFPNMSVFLGPLGVAYAMLRVQNPDVPSLLSLEI"
     misc_feature    complement(13089..13107)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.7"
                     /tool="antismash"
     misc_feature    13092..13110
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 21.91"
                     /tool="antismash"
     gene            complement(13137..13796)
                     /locus_tag="Bang102_RS07915"
                     /old_locus_tag="Bang102_007915"
     CDS             complement(13137..13796)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Bang102_RS07915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Bang102_007915"
                     /product="hypothetical protein"
                     /protein_id="WP_061111179.1"
                     /transl_table=11
                     /translation="MIALLYRDCLKARKPGFVALEILGICVTLAVESAMYDTLQPVMDV
                     FLSFVLPGLLVTISVFKLSSLVYGDYIFDIISSIHRAGYGIYGYLVERYVFSFLVVVPI
                     YAAGFIFGVLKHCFHDYSMAMADVASFVVVSFLALSVIMVCAINCSVEADSQTLLQLLI
                     LLVSSGAMALLMLLQYAFIPFYVFCIAAVLVTLCVNMIIARREKTMYCKTLLMLSK"
     gene            complement(13820..14500)
                     /locus_tag="Bang102_RS07920"
                     /old_locus_tag="Bang102_007920"
     CDS             complement(13820..14500)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Bang102_RS07920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Bang102_007920"
                     /product="hypothetical protein"
                     /protein_id="WP_045920226.1"
                     /transl_table=11
                     /translation="MKALLYRDLQLYKKPKYASFWLVTVFTAIIMEIWLGWMYEVGGGD
                     VMPITAKQGLVDSMLCTSFFASVYTNSFLLIEDRHVGIIKILHQSGRGMNYYLLEKIGF
                     TLPHNLLFVLVYIAVGIYMKLFYPSEVMCLLPTIGIAFMTSLTELSVANMLVFRLKDET
                     DRNVVFWGLIICGLICIGVAFVPLFGFPVWLSAAILIGVGFVAYLYTFVTYKTEYVKTI
                     SVFA"
     gene            complement(14574..14780)
                     /locus_tag="Bang102_RS07925"
                     /old_locus_tag="Bang102_007925"
     CDS             complement(14574..14780)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0005488 - binding [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03893.1"
                     /locus_tag="Bang102_RS07925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007925"
                     /product="lichenicidin A2 family type 2 lantibiotic"
                     /protein_id="WP_003826899.1"
                     /transl_table=11
                     /translation="MSNTSIDVDSIVGDDFSDLSPEDMALLTGRGNDVAPQSLSIAVSV
                     DVTVSVAMSVASYFHVGGTCKKH"
     CDS_motif       complement(14694..14780)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSNTSIDVDSIVGDDFSDLSPEDMALLTG"
                     /locus_tag="Bang102_RS07925_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14574..14693)
                     /prepeptide="core"
                     /locus_tag="Bang102_RS07925_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="3874.4"
                     /monoisotopic_mass="3872.0"
                     /core_sequence="RGNDVAPQSLSIAVSVDVTVSVAMSVASYFHVGGTCKKH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSNTSIDVDSIVGDDFSDLSPEDMALLTG"
                     /leader_location="[14693:14780](-)"
                     /alternative_weights="3892.4"
                     /alternative_weights="3910.4"
                     /alternative_weights="3928.4"
                     /alternative_weights="3946.5"
                     /alternative_weights="3964.5"
                     /alternative_weights="3982.5"
                     /alternative_weights="4000.5"
     CDS             complement(14943..15092)
                     /gene="allorf_1968211_1968360"
                     /locus_tag="allorf_1968211_1968360"
                     /protein_id="allorf_1968211_1968360"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNEQATLSVIFPESADSGCSFVAQTRQMDSMTASIVLTVCCIGMT
                     RLRS"
     CDS_motif       complement(14991..15092)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNEQATLSVIFPESADSGCSFVAQTRQMDSMTAS"
                     /locus_tag="allorf_1968211_1968360_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14943..14990)
                     /prepeptide="core"
                     /locus_tag="allorf_1968211_1968360_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.50"
                     /molecular_weight="1611.0"
                     /monoisotopic_mass="1609.9"
                     /core_sequence="IVLTVCCIGMTRLRS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEQATLSVIFPESADSGCSFVAQTRQMDSMTAS"
                     /leader_location="[14990:15092](-)"
                     /alternative_weights="1629.1"
     misc_feature    complement(14974..14994)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.37"
                     /tool="antismash"
     misc_feature    complement(15012..15028)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.22"
                     /tool="antismash"
     gene            complement(15127..16278)
                     /locus_tag="Bang102_RS07930"
                     /old_locus_tag="Bang102_007930"
     CDS             complement(15127..16278)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Bang102_RS07930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Bang102_007930"
                     /product="hypothetical protein"
                     /protein_id="WP_045920225.1"
                     /transl_table=11
                     /translation="MNDRIREVLTGLRQWCSARIPYILIAAALYALTFSNIALVLPLDM
                     VQIIYAAIAIVCIAGIIVMPLPASFGLGIVSIIGTLLPMTETVPNPLLTLFAVLGILGY
                     SSRLWICLLMLAVESVGVFIIQVAWHYDTGMDMYGVINSLAMLGCAIFVGYALRWRKQV
                     DLDRIDKMRLEHLQMRNRIAAGIHDSTTANLTKISQIAQHNIHTGGCENHAWSDVNRLA
                     VSTLRDIYKVIDLLSNEDSKQIMPSHGTFMEHLEDVTDAEDALLQNLGFRGKTEISGVA
                     EGISVQQEDVLLSLMREIYRNIQRHGNPNGTYKVVITIGNGRLLIAQSNEIHPVNDWHI
                     PHGRGIRLHNKQIELLGGKMQCWKKSRQWHLTVCVPLVSESES"
     gene            complement(16268..16933)
                     /locus_tag="Bang102_RS07935"
                     /old_locus_tag="Bang102_007935"
     CDS             complement(16268..16933)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="Bang102_RS07935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007935"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003826903.1"
                     /transl_table=11
                     /translation="MNDRQDSRIRVALVDNDAFTLDMLKMAIPRRNPRLDVCWSARRGA
                     DAIDWALDPVTMPDILLTDMSLEDISGVSVCREIRRRTERVPLLAITAFSIDRYANRAA
                     EAGAQGIIPKVNLNELVDSIDVIVKHGTLGMCGNIDFVDAKTAHQRLAESDMCPIQRLS
                     PTEQQILTLLAQGMEPRNIADMLSIGIGTVKTHIIRLRKKLNARSTKEAMAMWWNNER"
     gene            complement(17058..19832)
                     /gene="ligA"
                     /locus_tag="Bang102_RS07940"
                     /old_locus_tag="Bang102_007940"
     CDS             complement(17058..19832)
                     /EC_number="6.5.1.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="ligA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826907.1"
                     /locus_tag="Bang102_RS07940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_007940"
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="WP_061111180.1"
                     /transl_table=11
                     /translation="MSNESEQLAWDFDGLTGASANADDSKDERNGEPDIAIVANEGIAR
                     FPSGSEQWVAVLQATDEDALRLNRLDVSGMEADTAARLWAKVAAWVESDQIAYYIDDAP
                     VSSDAAYDARLRCLQRLEAAFPTLDNPQSPTRRVGGTFSNDFVSVRHPSRMMSLDDVFS
                     IEELHDWYDGVLRGLDWPEGKPLPMSCEVKIDGLALNLIYRHGVLEQGLTRGDGVTGED
                     ITLNVRTIGTIPANLAGPAEDIPDFVEIRGEVFMRWDDFRRLNDEQEDAGREPFANPRN
                     AAAGSLRQKDPRITATRRLSFYAHGIGRLEWGAGHAGHDEINDQSEAYELYTKWGVPVS
                     PHNRTVASFAEVLDMIDYYGEHRGDIEHALDGIVVKVDDLALQRSLGATSRAPRWAIAY
                     KYPPEEVNTELLDITVQVGRTGRVTPVAMLKPVHVAGSTVARTTLHNPFEVKRKGILIG
                     DTVVVRKAGDVIPELVGPVLERRKGRESELREFVMPEHCPSCGAKLAPAKEGDKDIRCP
                     NVESCPAQLTERVISLGMRKAFDIEHLGDQSAIALTNPEENRPDSVATFAPNITEILVA
                     PGEEPEEYEPVGGVELPPVQTPVLSSEAGIFDLTAADLKDVRVWREAPIIEVREVMGNN
                     GRKRKVRKRIGGSGLWHQVPAFWTTAAPAPKMRRKSGDDVGVVGGSALAERYPGFNVPA
                     DAVVVREETKTSRSGEITVTPIIVKPAENTRKMLEEIDKAKQADLWRVLVALSIRRLGP
                     PTARLIASAMGSLDAISKASVDDLTQIDGVGPEIAESVVHWFAAAREPGDWRGQTLTAW
                     RAAGVGVGEAAKSSLPQTLAGKTVVVTGSLEGFSRDSAKEAIVERGGKAAGSVSKKTDY
                     VVVGANAGSKAAKAEELGIPMLDEAQFELLLAGEYGADVAESTDDGVIEKELD"
     misc_feature    complement(19947..19962)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.35"
                     /tool="antismash"
     misc_feature    20234..20243
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.62"
                     /tool="antismash"
     misc_feature    21288..21303
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.04"
                     /tool="antismash"
     misc_feature    complement(21977..21993)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.65"
                     /tool="antismash"
     misc_feature    complement(22549..22562)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.27"
                     /tool="antismash"
     misc_feature    complement(22848..22863)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.13"
                     /tool="antismash"
ORIGIN
        1 gaaccaggac ggcgatgcgg gtcgggccac atctacacgt tccgtatgcg acactacgcc
       61 gatggtttca gtcatgctgt tcctcctcgc tgacaacgat acggcgtgcg tccaatgcct
      121 cgatcaatgc ctcatcgtgc gtgaccataa tcaccgcgga accggcgtca cgcacgtcgg
      181 cgatcaaacg caccatttcc gtccatgtgg tgaaatcctg accaaaggtc ggttcgtcca
      241 tcaccacgac cttcggcgcg gcggccatca tggatgcgac cgacagtcgc cttttttccc
      301 cgcctgacag tgtgaacgga ttggccgggc cgaatcgttt gagattcata cgttccagaa
      361 tctcgtccgc gatccgatat gcctcctcat ccgttttccc catggatttc ggtcctacgg
      421 caacctcgtc gcgcacgctg gcggtaacga actggtgttc cggctcctgg aacaccatac
      481 cgacacgccc cagcagatca cggctcttcc atgtgctcac atcattggcg cgatgcggcg
      541 gcaccatccg ttccgccatg cgcacatgac cggcaaacgg ttcgagcaga cccgccaaag
      601 taagcgcaag cgtggatttg cccacaccgt tgcgccccgt caatgcggtg acctcgccgg
      661 catggaattc cagatcgata tgtttgccaa gcgggaactc acggccgaag ctcagatcgt
      721 cggttcgcag caccacctcg ccggcagacc gctccggatg atacggcgtg atggctcgcc
      781 caggcaccca tgcgccgcct tcggcaagca catcgcccat ggtgccaaac acctcgcccg
      841 gcgtgccatc cgcaatcacg ccgccggtca gcgaattgcc gtcaggcttg cccagtacga
      901 tcacgcggtc aaccgtgtca agccacacat cgatatgatg ctcgaccacg atcagcgttt
      961 ccccggtgcg ctcgaccaca tgcttgacgg catcatggac ttccttcacg ccgtcgggat
     1021 cgagattcgc cgtcggctcg tcaaggagca ataatccggg gtgcatggcc agcacaccgg
     1081 ccagggcaag acgctgacgc tgaccaccgg aaagcttgcg tgtggaatgg tcgaaacgca
     1141 tgtagtcaag tccgacgatg tccagtgatt cgcgggcacg ctgccagatc tcgtctttgg
     1201 gcaaccccag gttttcgcat ccgaacgcga catcatcgcc cacacgttcc agaatcgtct
     1261 gcgcgtccgg gtcctgcaat accaggccgg agactccacg cgccttacgt gcgtccccgc
     1321 caccaaccag cagcgtcccc tcctgctcgc catcatcatc gccgccaagc acgcctgcca
     1381 gtccagccat cagcgtggat ttgccggcac cagaagcgcc aagcaacagc acacgctccc
     1441 ccggccggat gtcgaagtcg acatggcgta gggcgaaatc cttacgtgaa gcgtgccgcc
     1501 acccccagtt gcgcgcggac acgcctaccc ccatggaacg ttccccggcg ccggcatacg
     1561 catctgcgct catacgagca tccgcaccgg tatcggctcc gattccggca tcatcaccag
     1621 aggcaacggt aaccatcgaa atccccctca acaagcaata cgtcgtaata cgtaaacaat
     1681 caaacaaaca caacgggtcc cacgccgcac accagcggca tgggaccctg gccgctcaga
     1741 ccagcgtctg ggcgcgaccg gactcgaaac gatcgagtac accggtctgt gcgatggcac
     1801 gatgcagcag gtacatcacc acgccggcca gcacaacgcc ggaaacaatg gacgtgccca
     1861 ggtaaatgct ggaacgcatc acaccccatg ccgggttcat aacccagtag tagatgccac
     1921 agcccacgcc ggccagagcg ccggaaaccg cggtggtcag catattccac ttcttgtagg
     1981 cgaagatcgc gaatccgatt tccgcgccga tgccctgcat aatgcccacg atcagcgaac
     2041 cgccgacgcc ccactggtta cccatggtca gttccagggc ggcggcgagc gtttcggcga
     2101 acagcgcggc accaggcttg cgcacgatga tggcggcaag cgggccggcg aacagccaaa
     2161 acgcgttcag caggccttcg aagcccggcg tcacagcgcc gaaaatggcc agcggagccg
     2221 cgcagacaat atcccagccc cagaagatca cgccggatgc cacggcgatg atggcggcca
     2281 ccacgatatc gaccacacgc caggtattgc tgtgcttgcg gaccgcggag gattcgttct
     2341 ccacggcatc gattgttggt tcagtcatta ctgtgccttt ctctcattca aggcacggga
     2401 agagagacgt ccgtgcgccg gaattgcccg gtaaacgttc atacggtcga agcgttcgct
     2461 tcctctcagc ctcacggctc ccgtgtcatt gcccgataat acgcagcacg ctcgatttcc
     2521 cgtcttcgct tccacgagca tcggcggctg tcggcgccga acgcgcggga gcatgctcct
     2581 tcaatccccg gaaatgctct aggatggcct aagaagagcg aaaggaatgt tatgaccgcc
     2641 gaaacgaata ccaataacgc atcggacatg ccggtctccg accaaccagt ttccagccaa
     2701 ccgtcacaga tggggcagac gaacggagga aacaccaagc ctgcccatgc tggatccgcc
     2761 gtcaaagccg cgctggccgc caatgtaggt gtggcctgcg cgaaattcgc cgcagccgct
     2821 ttcaccggat catcctccat gttctccgaa tcggtgcatt ccgtggctga ttgcgcgaac
     2881 gagatcgtgc tcatgttcgg cgaccgtgcc tccgaccgca agtcaaaagg cgaccatccg
     2941 ttcggcatgc atcgtgcgaa ataccttgcc agcttcatcg tcgccacgct gctgttcttc
     3001 gtcggcggcg tgttcgccgt cagtcaggcg acgaagaagc tcatcggatt gctcgacggt
     3061 tccgtggacc gccaggtcga ctcgcttgaa ctgcttgccg cgctggccgt ggtcgtgatc
     3121 tccgcctgcc tcgaaggcta cggcctgcac acgtccatca aggaagcacg cgagcgcatg
     3181 gatcgcgtaa aggtcgagaa ggattcgctg atcggcttct ggaagcgcac caagtccgcc
     3241 gaactcgcgt cggtgatgat ggaggacacg ctcgcgctga tcggcctgct gttcgccggt
     3301 cttggcatcg gctgctcgat gctgaccggt gatgaactgt acgatacgat cggtggtctg
     3361 atggtcggct tggtgctggt gattggctcg gccgcgctgg cgttcaaatc cggttcgctg
     3421 ttgctcggcg aggatgtgga tccgcgtacg cacaagctgc tttcgcaggc ggtgaacaat
     3481 acgcctggcg tggaacggct tatcaatatg caagcgattc acatggatga ggatgccgtg
     3541 ctgctgtgtt tgaaggtgca gacgtccaag ttggaccgcg actacgatgt ggagactgtt
     3601 gacaagatcg agaagaacat tcgcgtcgca ttgccctggt atgagtggga gatctatgta
     3661 gaaccggata tctggcgtgc gaaccatgtc tccgctgagg aatagcggct ttccgttttc
     3721 gtttcgcata tccgagcaac gccattgatt cggccgtctg tgtttccggt gcatgttcta
     3781 cctatgatgc gcggtggaaa cgcaggcggc cgaacacggt tctggcgtgg cacgggacca
     3841 cccgctaagg tggtaggcgc acacaggagg atcatgaacg acattcacac catcgaagcg
     3901 aatattttcg aacgactcag ccatgtcatt gacccggaac tgggccgttc cgtcaccgat
     3961 ctgggcatga tcacgtcgat cgaggccgtg ccgtccggca ccgtcgacga gaacggcgac
     4021 ggcatcatcg acgtaaccgt gcatgtggag ctcaccgtca aggattgccc gttgagcgaa
     4081 accatcacca atcagatcaa cggtacggtc cgatcctacg tggcgcccgg ctcccctaac
     4141 gtcacgcttg ttccgcatat cgaggtcagc tccatgccgc aggacaagct gaccagtctc
     4201 gtgcagacgc tcaaagcaga gcgccggcag aatccgttca gcaaacccgg tatcaagacg
     4261 cgcatcttcg ccatcgcatc cggcaagggc ggtgtaggca agtcctccgt aaccgccaat
     4321 cttgcagcca ctttcgccgc gcttggctac gacaccgccg ccatcgacgc ggacatctac
     4381 ggattctccc tgcctcgcct gttcggcgtg catacgcagc ccacgaatct gaacggcatg
     4441 ctcatgccgg tgaccgcatg gggcgtgaag cttatttcaa tcggcatgtt cgcgggcgcg
     4501 gaccgtgcga tcctgtggcg cggccccaga ctgcaacgct cgttggagca gttcctgtcc
     4561 gatgtgtggt ggggcgagcc ggatgtgctg ctgctcgatc ttgcgcccgg caccggcgat
     4621 atggcgattt cggtggcgca ggcgctgccg aatgccgaac tggtggtggt gaccacgcca
     4681 cagccgtccg cttcggatat tgcggtgcgt tccggcttgg tggcgctgca ggtgccgatg
     4741 aaggtgcggg gcgtggtgga gaatatgagc tactacgagc ataagagcga gaaactgcgg
     4801 atcttcggcg agggcggtgg ccagcgcgta tccgaacaac tgaccgcggc gctaggccat
     4861 gatgtgccgt tgatggcgca actgccattg atgcccgaac tgcgtgagac cggtgaagag
     4921 ggccggcctg cggtgctgac gccggagggc gcgttagcca acactcctct ggcggacgag
     4981 ttcacttcgc tggcgcgaca gcttatggaa ctgcactgag tcgccccctt gccgcgcttt
     5041 gggtgtcaat tcggacgttt tccgctggtt gggtgtcgat tcggacgctt tcgggcccaa
     5101 tttcgtccga atcggcactc atctgcctga tttcgtccga atgaaccacc aactgcgcga
     5161 taccgtccga agcgaccacc ttccatgaat gcgcaccgct gcgactgccg gtaacgcaac
     5221 agtgcgagaa tgccggtatg agaatcgcca tcgcacagtt tgcggtcgat cgcgaaccgg
     5281 atcgcaatat cgagaccatc cgcacctatg ccatgcaggc ctcagccaac aacgcacgtg
     5341 tgctgctgct acctgagggc atcatcgcac gggacgcgac cgacccgtat tacccggcac
     5401 atcacgcaca gccaatcgac ggaccgttcg tcgcggcact acgggcgatc agcgcgcaga
     5461 ccggcatcgc gctgatggga accgtgcacg taatcaaccc ggaaactccc aagccaagta
     5521 acgtatttct tgttatcgac aacggtgaga ttcgcctcgc ctaccgtaaa atccacctgt
     5581 acgacgcgtt cggcgagcgt gaatccgacg tgatcgagcc gggcaacgag gttccgccgc
     5641 ttatcaccat cgacggttgg cggttcggtg tgatgacctg ctacgatctg cggttccccg
     5701 aactggcacg ggcgcatgcc attgccggcg cggacgtgct ggtcgtctcg gcagcctggg
     5761 cgcgtggagc ggacaaggtg gatcattgga cgacactgtg caaggcgcgt gcgttggaga
     5821 atacgtgcta cttgatggca tgcagcgagc acagcgcgca taacatcgga catagcatgg
     5881 ccgttgaccc gctggcgcat gtgatcgcac agtcagaaag cgacgacatc gtattcgcgg
     5941 atttcgaccg ggatacgttg gataaggctc gccagacgct gccggtgcta cgcaataggc
     6001 gttttacagc gccggtgctg cagggcgcga cacggacgac tgattagccc ctgcattcgt
     6061 ttgaaacaac cgaccgtgca gcagatggat gtcgattcgg acgctttccg ctggttgggt
     6121 gtcgattcgg acgttttcgg gcccgatttc gtccgaatgg acagccgaat agagaaaaca
     6181 gcagagcaaa aatcatcaca gccagcgcat tcagtactaa tgctgacgat ataactttgc
     6241 gtacaacttc ccctcggcca ttaagctctc atgcgaccca tgttcaacaa tatgcccatc
     6301 atccatcaca tatatctcat caaacatgcg tatcgagctt agcctgtgcg ccaccaccac
     6361 acacgcgtat ggcgcacgca taagggctct cattatcttg ttttccgtaa cattatccag
     6421 cgcactggtc ggctcatcca tcaccatgaa catcggattg gtcaccatgg cacgggcgat
     6481 tgcgatcttc tgcctctggc ctccggaaag attcaaacca tgttcactga tcatggtgtc
     6541 cagtcccaag cccggattca tcatcgattc atcgatgcaa cagtccttgc acacttgcct
     6601 taatcgagat tcatccacgg atgtccgtcg cagcaggata ttttcacgca acgtcatatt
     6661 gaaaaccgtt gtatcttgat ggacaaaagc aatgttcttt gcacgccacg aaagcggcaa
     6721 ctcttcacat gaatggccat cgaccatcac tcttccctgc gtcggacgaa tcaatccgga
     6781 aagaagcttg agaaccgtgc tcttccccga accagtgggc cctactatca cgaccttgcg
     6841 ccccttggga atatgtaaag taatgtcttc tactacgggc ttggaaaaaa ccgtatacga
     6901 aaatgagaca ttgtgtgcag tcagactctc ccggccatag ttatcgatac gctcggaatg
     6961 cggcgcagca tagcacgagg gattttcttg gctctcccct attcccgtta tctctttgcc
     7021 gctctgggaa tcactcggca agactctttg gagaggagca tgttctccat ccacatgccg
     7081 catctcataa tccatatgcc cgtcattagt tcgttttcct gatggaataa tgtctgcaat
     7141 cttgcggata tatgagagaa cggcagcaaa ctgcccaatg gacgtcatga tgctgccgaa
     7201 tggcacaaca aacgaagaag ccaacgttac gaatccgact accgtaccca agtcgaccat
     7261 atcttgagca agcagcacgg aaccgcatag gatgatggcg agaggcaata cgaattccag
     7321 tgccgccgac agtgacgaca tccatgcatc gagtttgccc ctcttccact ggaagtgaag
     7381 ctgcttctgc agtaaatcag accagcgccg ataaaagaag ccctccagat tcatgctttt
     7441 tacggtctct attccggaga aaatttcaat aaaggactgt tgcactgcgg attgtgcagc
     7501 ggtctcctta tcaaccagct ttttggattt cgcagcatat atcgtcgaga ccatgagaat
     7561 aacaaagcaa atcgccaatg tcaccattgt gagctgcggt gagtagttga tcatcatcac
     7621 cagatacacg gcaagaaaca cgaaggacac cagcgatcca atcattccgg tagccagcat
     7681 ttgttcaacg acagccacta gattcgcccg gtagatcata tcgccgcttg ttcggtttat
     7741 gaaaaaggca aactctcgtt caaacactcc ccgcatgtat ttgcggaata gaaagttccc
     7801 aaaccctatc cttaatcgag cgttcgccaa tccattgagc atggaaatca ggtaatacag
     7861 cgcaaaagaa acaagcatca tcacgaacgc ggccagcaga aacccctcgc tggtgcacag
     7921 ctgccgacga ttgacgataa atctcattcc tgttggagga atcaatccca agctttgtat
     7981 tgcaagcgac aatactatgg cactcaacac gaaaaccggg gaagaaacaa ggaagtcctt
     8041 aatcactccc atgcaattcg agtcgcgcca tgccccgcga atggatcttt tctctcccgc
     8101 acgctcggta agcacagccg ccgaggagca gtgcctacga aaatcctctt ctcgcacgga
     8161 tgaacgccca ctcgccggat caataatata gaaacggccg aatgcgtaat gactcaagac
     8221 tacgaagtga tgatgattcc atagcaggat ggacggcgaa tccagttttt tgaatccatc
     8281 gatattccgt actgcaacgg cccggttcgt caccccgtaa tcattcagaa tggtcactat
     8341 atttttgatg cttagcccgc cacgaggaac accatacgca ttacgcaaat cctccaatcc
     8401 ggaatcgcgc ccatacgcct tgagtatcat ggcacatgca gccaagccac attcgctgtg
     8461 ctccccctgt tcgacgagag ggatacgcaa atgccctgcc atacaaagcc tcctcttaac
     8521 ttacaagcca aaatcaacat gctcatgttc tttgccgagc atcgcggcct ttgagaattc
     8581 atcaaacgag ttgaaatcgg agagcatcgc atccagggca atatgcttgt gatcaagcac
     8641 gataatacga tcagagacgt tccagcaata atgcaggtca tgggtgatcg taagtatcgt
     8701 acggttatcg gcacgtagcc ttcccatata ctcaatcaac agatcacgtg tcagcggatc
     8761 aatggcattc gtgggttcgt cgagcatgat gacatgcggg tcgaacatca tgccggccac
     8821 tattcccact cgtttgcgca atcctgagct taggtcagag acctttttgt ccagctggtc
     8881 gttcaattcg aatgcccgaa ctaatggatt cttctccaag gcttcaaaaa aggtcttatc
     8941 gtcatccttt ggcttgaata gcatcttgcg gaacttgaaa ttctctcgta cggtcatcgt
     9001 gtcaataagg ccgccctgtt cggtcatttg gaatacgtct cttattgagg gaacaaacgc
     9061 tttgttaatg gcagcgtacc ccgaccaggg ccgccgtaat ccaactatga gatcgaacaa
     9121 cgtggttttc ccaacaccgt tatagcccaa aatagccaat gactgtccct tggggactgc
     9181 aaaggtgata tgttcgagca ccgcctgctt acgcttgtac ccaaaggtca agtcgtttac
     9241 tctgataata tccgttgtgt tcatgtgtat tcctttcagt gctccacctg tggtaatgac
     9301 gcaaagtact ccgccaagct gtcacaatcg aacatgcggt gctttttcca ataccgatat
     9361 tcggcgtttt gttcatcccg gcggatatac gaccgtttat aagaatgaaa cagttcctct
     9421 tgataaccat taggcatgga agcctcgtgc gacgtaagcg cagaaagaat atgccgagcc
     9481 gcgccctgtg cctcattgtt ttcaaaaggc atgccatatg tgttgtatgc agtcggatct
     9541 cggacaatgc ccagagaatc catgaaacgc tccagcatat cgccaacttt gagatatccg
     9601 ttcgtgctgg cgcttacgag gggcatcccc ggcttgccgc tcagatagaa caaatgagac
     9661 cagtagcata atctatccat tacgatcttc atgtcacccg acacgttatg cccatatgtt
     9721 ggcgaaccga gaatcaggta atcgcaatgc tcaatcattg ttttcaatct ccccgaatca
     9781 tcgattccaa ggagctcctg ccggtcaaca ccggtcgaga attcctgcgc tgtaccgtca
     9841 gagggaagga tacgcagatc tttaggcgtg catatggtcc acgatatttg cgtatcgata
     9901 ctgtcttgta gtgaggaaag ccattgcttt attaagacga tggcctgcaa tgttcgggat
     9961 tgcgggttgc gggaaccaca gtaggcaaaa attctgtaca ttagatctcc agtgaaagta
    10021 gtgatggcac atctggattc tgaaccctca gcatggcgta tgccacgcca agtggtccga
    10081 ggaataccga catgttcggg aatgcagaga ccttcccaaa atcaaaatgc ttgttgcacg
    10141 atgcggcagc gaccatatcg tccatgaggt gacgcgccaa cgccgagtat cgttcgtcat
    10201 tcgtgttccg ggccagtgag acaagaacgt caatcgcacc ggaacgaccg tggcacaaag
    10261 aatcgtccac ccagtcgcat gaatcgatga gctgttttac cgatgaaaac tcagggaagg
    10321 gcttgcctgc atcatcaaaa aaacgacgtc cgtaggcagt gcatcggtca atctcattct
    10381 gcgcccataa caggccgact gtacctcgac accacttgcc gcgctccctt gaggaccgta
    10441 ctggctgagc cttatgcttc gccatggcct tttcccatat cttttgcgca tcatctgcaa
    10501 attcggtatc gccgacggcg gcatacagac gccacagagc tacgctgatt ccttcaagac
    10561 catgccctgc gccggcagga aaactgtcgt ccgaattagc attttcctcg cgttgcaatc
    10621 tacaagctgt ttttgcaacg attcttccta attgggataa ttggatgagg atatcgtcat
    10681 cccgaagaag ctcccatatc ctcagataca gtatgattac actagacgca ccggcaaggt
    10741 aatccatacg gtaggtaaac ctgttcgcct taccgacctt cgacaatcgc acggattcgt
    10801 ctttcacata acgctccaaa cgatccataa tctgcaaagc agagttcgtc aagatatcgg
    10861 actttatgcc aaggctccgg agcattaacg ccgggtatat ctgcgatagc ccaccggtaa
    10921 aagccgattc cgaagcgcta ggcgaggtac gtaattggat tgaccgcatt gttttcaatg
    10981 cataatcggc acaacgtcta tcgccaaaag cttgtgacaa gcttgccagg aaaatggcgg
    11041 ttccaccaca tccgtcatac agatcaggag aaggcacgcc aacggcattc gcatcgttct
    11101 cagattcccc tgattgcttt gtgcagatcc acgataccgt gctgccatca tcggatagta
    11161 tcgcttgatc aaccagataa tggcctatca tgagaggcca ctcgttgatg gaagaagaga
    11221 ttgccggacg ctggcgcact agcatatgga atgcatttct gataagagac tcctgcaatc
    11281 tggcttcttc atgaagatgt ctcttggttc gcataatacg ttcgatggcg ctgtatgcga
    11341 atgagggacc gcattccctt ccttctccat ccctcaatat cttggaatca agagaagtaa
    11401 caaacattgg aatatcacca tgaatcatct gctgatactc actaagaaag atatgcttgt
    11461 ttttgtatgg gaatacataa agattctcta atatcgcctc tactttagtc atgtcatcaa
    11521 gcaccttcgg gtgatgcatg taattcaaga agcgagcata tacgctggtg gcccttacga
    11581 gaacgcgaac cgttgctttc ccgcgttgca gaatgcggca taacgcatcg tccgaaatgc
    11641 ggtccaacgc atgcactcca tgtgtaaagc catcaagaat ttcatgagca tagtcagacg
    11701 gattaacgac atcatcgtta taatgcagaa cattatcttt tttactaaaa acgacatgtt
    11761 gcttttgaaa acaagcgccg tccgtatcaa gcattaccgg taccggaaat agcgtgggga
    11821 cttcctgatc tttgacattc agcgcactaa aatcgattga ttctccttcg gtattcagca
    11881 ccatgcgtgt cgggaggaag gacgttccag ccaacgagtc acgcaaccgc ctcgccactt
    11941 tcacgtcagc ggtctctcgc agactgtttt gggaatccat ttccacatag ttggagcaca
    12001 cggtctcata gtcgatgatt tgcggatatt caccatcgga gatgatgttc tcataatgca
    12061 tgtcattgcc gtgcagaaac cacaccaggg caagaagctc gccgattctc aggtagtaac
    12121 gagatacctg gtcacatgtc agacattgcg actgccgcac gaattcctca aacgcatatc
    12181 catcttcggg aagcactctt gagacatgca gaggcaggaa atcatcggac cgttcacatt
    12241 catgagcaag atcggcaaac agtacatgaa tcgaaagatc acgtggcttg taaacgactc
    12301 tgcttccatt attgaattcc agaatggcga ccgtacgacc atgattatgc gcgtccccgc
    12361 catcgagacg aatatcactc aacacgagcg gcacagtgct cttcaggaac atcttgagtt
    12421 ccgaatcaga ctcttcaagt cttgtgaaca tttcacgtat aaaggcaata taatccgtgg
    12481 tcgcttgtgt cagcatgcga gccagcaccg gataccgaga gtacaacaac cgctgatacg
    12541 catacgttga agccatgtgt atgaaggaaa gcatacgttc atgcccgtca gccccctgca
    12601 aattcccatc cgcgttctca cggcgcatct ccaacaccag tgttttcaaa ccgatgttca
    12661 gcagacgatt agccaatgtt cctcttatgc tgttttgaac attgtcatat gagttcatct
    12721 gcgaatcggg aattgttgtt ctcagcgtct tttccgcata aagaataaaa ggcatgaaga
    12781 tattaacata tcctacgtta atatcttcaa cgaatttgct gtttgaaaag aaggcgaata
    12841 tcttttcaaa atcagaatac catgaagaaa gattgccctt gtttcccttt aaaaacgact
    12901 ttccatcaat gcatttcgca tattttttct tatcataacc acgaagctca agcatgctgg
    12961 caaaatcatc ggggcgcaac gcgcaatttc gcgacatcca ttgactgata acagaatcga
    13021 caaacgaatc atcaccggaa gcgtcatcgt catcaatcaa cgaatagcgt tcttcgatgg
    13081 tatccgcata catacttttt acaatatcca cagcatatcc ccttcaatga attacattat
    13141 ttactcagca tgagaagcgt cttgcagtac attgtttttt ctcttctcgc gataatcata
    13201 tttacgcata gtgtcaccaa aaccgcagct atgcagaata cataaaacgg tatgaaagca
    13261 tattgcaaaa gcatcagcaa ggccattgca ccactcgata ccagaagtat cagaagttgc
    13321 aacaatgtct gggaatccgc ttcgacagaa caattgatgg cacataccat aatcacagat
    13381 aaagccaaga aagaaacaac aacaaaagaa gccacatcag ccattgccat ggaataatca
    13441 tgaaaacaat gtttcaatac tccaaaaata aaaccagcgg catatattgg cactacaacc
    13501 aaaaaagaaa acacataccg ctcaacaaga tatccataaa taccatatcc cgctctatga
    13561 atcgaactta ttatatcgaa aatataatct ccataaacca aagaagacaa cttaaaaaca
    13621 gaaatcgtca ccaacaatcc aggcaaaacg aaagagagaa acacgtccat tactggctgc
    13681 aatgtatcat acattgcgct ttccactgcc aacgtcacgc aaattcccaa tatctcgagt
    13741 gcgacaaatc cgggttttct tgccttcaag caatcacgat acagcaacgc aatcatacaa
    13801 tcaccaacac catacagcac taggcaaaaa cagatatcgt cttcacatat tcggttttat
    13861 atgtgacaaa cgtatataga taagccacaa aaccaacgcc aatcaatatg gcagcactca
    13921 gccacaccgg aaacccaaat aggggaacaa atgccacacc tatacaaatc aatccgcaaa
    13981 tgattagtcc ccaaaatacc acatttcgat cagtctcatc ctttaatcga aagaccagca
    14041 tattggcaac cgataattcc gtgagcgatg tcataaaggc tatgcctatt gtaggcaata
    14101 ggcacattac ctcagacgga taaaaaagct tcatatatat tccgacagca atgtatacga
    14161 gcacgaacag cagattgtga ggcagcgtga atcctatttt ctccagtaaa taataattca
    14221 tgccacgccc cgactgatgc aggatcttga taataccgac atgcctgtct tcgatgagaa
    14281 ggaacgaatt tgtatatact gacgcgaaaa acgatgtaca taacatacta tcaacgagtc
    14341 cttgcttcgc ggttataggc atcacgtcgc cccctccgac ctcatacatc cacccaagcc
    14401 agatttccat gattatcgcc gtaaaaacag ttaccagcca gaaactcgca tacttcggtt
    14461 tcttatacaa ctgcaaatcc ctgtacagca gcgctttcat atgcaccccc ttatagaaag
    14521 ggtgccgcgg catataagcc acgccgcaac acccagatct caccagtcgt cggttaatgc
    14581 ttcttgcagg ttccgccaac atggaaatac gatgcaacag acatcgcaac ggaaacggtg
    14641 acatcaacag aaaccgcaat ggacagtgac tgcggggcca catcgttgcc acgcccggtc
    14701 agcaaggcca tgtcctcagg cgagagatcc gaaaaatcat cccccacaat ggaatcgaca
    14761 tcaatactcg tattgctcat agcagagcct ccttcaacgt acacaccgtt aggtggcttc
    14821 cggagcggaa gcgcggccag tataagctct tcgcagcaga gatcgcccac ccgtgtatcc
    14881 cagaggaata cacgaacttt gtattgtggc tggtctttat atcattgttg ttgtcgtcaa
    14941 tatcaagaac ggagccgtgt catgccaata caacatacag tcaaaactat gcttgcagtc
    15001 atgctatcca tttgcctggt ttgcgcaaca aacgagcaac cgctatccgc cgattccggg
    15061 aatatcacac tcaatgtggc ctgttcattc atgccatggc tgtgccatca ttagcatctc
    15121 acgagcttag gattccgact cgctaaccag cggaacgcat accgtcagat gccattgtct
    15181 gctcttcttc cagcattgca tcttcccacc cagcagctct atttgtttgt tgtgcagtcg
    15241 gatccccctg ccatgaggaa tatgccaatc gttcactgga tgaatctcat tggattgcgc
    15301 gataagcaat ctaccgttgc ctatcgtgat aacgaccttg tatgttccgt ttggattacc
    15361 gtgccgttga atattgcgat atatctccct catcaacgac agcagaacat cttcctgctg
    15421 caccgatatg ccttcggcaa ctccggatat ttccgttttc cctctaaagc ctaagttctg
    15481 cagcaatgca tcttccgcat ccgtaacatc ttccaagtgc tccatgaatg tgccatgcga
    15541 tggcataatc tgcttggaat cctcattgct gagcagatct atgaccttat atatatcccg
    15601 caaggttgag acagcgagac gattgacatc agaccaagca tggttttcac aaccaccagt
    15661 atgaatatta tgctgtgcaa tctgcgatat tttagtcaga ttcgctgttg tggagtcatg
    15721 aatgccagcg gcgatcctat tcctcatttg cagatgctcc agcctcatct tatcgatgcg
    15781 atccagatca acctgcttcc tccaacgcag ggcatatcca acaaaaatcg cacagccgag
    15841 catagccaga gaattgatca caccatacat atccatgccc gtgtcataat gccatgcaac
    15901 ctgaataatg aagactccca ccgattcaac tgcgagcatc aacaggcata tccacaggcg
    15961 ggacgaatac cccaatattc caagtaccgc gaataaagtc agcaaagggt tcggcaccgt
    16021 ctctgtcata ggcagcaacg tacctatgat agagacaatt cctaaaccga acgatgccgg
    16081 taagggcatg acgattattc cggcaataca tactatggca attgccgcat agataatctg
    16141 gaccatatca agcggaagca caagtgcgat attcgaaaaa gtcaaagcat agagcgcagc
    16201 ggctatgagg atatatggga ttcgcgcact gcaccattgc ctcagccccg tgagaacctc
    16261 tcgaattcta tcgttcattg ttccaccaca tcgccattgc ttccttggta ctacgcgcat
    16321 tcagcttctt gcgcaatcgg ataatatgcg tcttcacggt gccgatgcca atggacagca
    16381 tgtcggcaat attgcgaggc tccatgcctt gcgccaaaag cgtcagaatc tgctgctccg
    16441 tgggcgatag gcgttgaatc gggcacatat cggattccgc aagtcgttga tgcgcggtct
    16501 tcgcatccac aaaatcgatg ttcccgcaca tccccaatgt gccgtgcttg actatcacat
    16561 caatcgagtc aacaagttca ttgagattga ctttaggaat aatgccctga gcaccagctt
    16621 cagcggcacg gtttgcatag cgatcaatcg agaatgccgt gatagcaagc aacggaaccc
    16681 gctcggttct tcgacgtatt tccctgcaca cacttacgcc actaatatct tccaggctca
    16741 tgtcagtcaa taagatatcc ggcatagtaa cgggatccaa agcccaatca atggcatcgg
    16801 cgcctctacg cgcggaccag cacacgtcga gccgtgggtt cctgcgaggg atggccatct
    16861 tcagcatgtc caaggtaaag gcatcgttgt ccaccagtgc cacgcgaatg cgggaatctt
    16921 gacgatcgtt catatttcat agaatagctg tactcccaaa agctgagcag gaatccacca
    16981 acagttgggt gccgattcgg acgatttcgg gcccgatttc gtccgaatcg gcactcatct
    17041 gcctgatttc gtccgaatca gtcgagttcc ttttcaatca cgccatcgtc cgtgctctcg
    17101 gccacatccg caccgtattc gccggcaagc agcagttcga attgcgcctc atccagcatg
    17161 gggatgccaa gctcctcggc cttggcggcc ttggaaccgg cgttcgcgcc gaccaccacg
    17221 taatcggttt tcttgctcac cgagccggcg gccttgccgc cacgctccac gatcgcctcc
    17281 ttggcggaat cacgcgagaa gccctccagc gaacccgtca ccaccacggt cttgccggcc
    17341 agggtctgcg gcaggctgct cttggctgcc tcgcccacac ccacaccggc cgcacgccat
    17401 gcggtcaggg tctggcctcg ccagtccccc ggttcgcgcg cggcggcaaa ccagtgcacc
    17461 accgattcgg cgatttccgg ccctacgccg tcgatctgcg tcagatcgtc cacactcgcc
    17521 ttgctgatcg cgtcgagcga tcccatggcg gaggcgatca gtcgcgcggt gggcggcccc
    17581 aggcggcgga tcgacaatgc cacgagcacg cgccacaggt cggcctgttt ggccttgtcg
    17641 atttcctcaa gcattttgcg cgtgttctcg gcgggtttga cgatgatcgg cgtcaccgtg
    17701 atttcgccgg aacgtgaggt tttcgtctcc tcgcgcacca ccacggcgtc agcgggcaca
    17761 ttgaaacccg ggtagcgttc ggcaagggcg gatccaccga ccacaccaac atcatcaccg
    17821 ctcttcctgc gcatcttggg cgcgggcgcg gcggtcgtcc agaaggccgg cacctgatgc
    17881 cataggccgg atccgccgat cctcttgcgc accttgcgtt tgcgcccgtt attgcccatg
    17941 acttcgcgca cctcgatgat cggcgcctcg cgccatacac gcacgtcttt gagatcggcg
    18001 gcggtcagat cgaagatacc cgcctcggag ctcagcaccg gggtctgcac gggcggaagc
    18061 tccactcccc ccaccggctc gtattcctcc ggttcctcgc cgggcgcgac taggatctcg
    18121 gtgatgttcg gcgcgaacgt cgccacggaa tccggcctgt tctcctccgg attcgtcaac
    18181 gcgatggccg actggtcgcc cagatgctcg atgtcgaatg ccttgcgcat gcccaacgag
    18241 atcacacgct cggtcagctg cgccgggcag ctttccacat tcgggcagcg gatgtccttg
    18301 tcgccctctt tggcgggcgc cagcttcgcc ccacagctcg ggcaatgctc gggcatcacg
    18361 aactcgcgca actcgctctc gcgccctttg cggcgttcca ataccggccc caccagttcg
    18421 gggatcacat ctccggcctt gcgcaccacc acggtgtcgc cgatcagaat gcctttgcgc
    18481 ttcacctcga acgggttgtg cagcgtggtg cgggccacag tggagccggc cacatgcacg
    18541 ggcttcagca tggccacggg ggtcacgcgc ccggtgcgcc ccacctgcac ggtgatgtca
    18601 agcagttcgg tgttgacctc ctcgggcggg tacttgtagg cgatagccca gcgcggcgca
    18661 cgcgaagtgg cgcccaggga acgctgcaac gccagatcgt ccaccttgac cacaatgccg
    18721 tcgagcgcat gctcgatgtc gccgcgatgc tcgccgtagt agtcgatcat gtcaagcact
    18781 tcggcgaacg aggcgacagt gcggttgtgc ggcgagaccg gcacacccca cttggtgtac
    18841 agctcatagg cctcggactg gtcgttgatc tcgtcatgcc cggcatgccc cgcaccccat
    18901 tcgagtctgc cgatgccgtg cgcgtagaag ctcagacggc gggtggctgt gatgcgcgga
    18961 tccttctgac gcagcgaccc ggcggccgcg ttgcgcgggt tggcgaacgg ttcgcgcccg
    19021 gcatcctcct gctcgtcgtt gagtctacgg aagtcgtccc agcgcatgaa tacctcaccg
    19081 cggatctcca cgaagtcggg gatgtcttcg gcggggccgg caagattggc cggaatggtg
    19141 ccgatggtgc gcacgttaag cgtgatgtct tcgccggtca cgccgtcgcc gcgcgtcaac
    19201 ccctgttcga gtacgccgtg gcggtagatg aggttcaacg cgagcccgtc gatcttgacc
    19261 tcgcagctca tcggcagcgg cttgccctcg ggccagtcga gtccgcgcag cacgccgtcg
    19321 taccagtcgt gcagctcttc gatggagaac acgtcgtcaa gactcatcat gcgcgagggg
    19381 tgacgtacgg acacgaagtc gttggagaaa gtgccgccga cgcgacgcgt gggcgactgt
    19441 ggattgtcga gcgtggggaa cgcggcctcg agccgttgca gacagcgcag gcgcgcatca
    19501 taggcggcgt cggagctgac cggcgcatca tcgatgtagt aggcgatctg atcggactcc
    19561 acccatgcgg cgaccttcgc ccacagccgg gcggcggtgt ccgcttccat gccggagacg
    19621 tcgagccgat tcagccgcag ggcgtcctcg tcggtggcct gcagcacggc cacccactgt
    19681 tcggagccgc tggggaatcg tgcgatgccc tcattggcca caatggcaat gtcgggttcg
    19741 ccgttccgtt cgtccttact gtcatccgca ttcgccgatg cgcctgtcaa accgtcgaaa
    19801 tcccatgcca gctgttcgct ctcgttgctc atactccccg attctattcg ctcagcgaac
    19861 ggatgaactg cgcctgcacc acgtcaatgc cgttcgactc cgtgtcgttc atacgtgccg
    19921 ccgccaccgc cagcgtacgg gcgggaacga acaggccttc gtccacggtg atgcgcacgg
    19981 cctggcgcac gatgccggcg gcttcggtgt ccggccagac gggcagaccg tgatgcttga
    20041 gcaccatggc ggcctcctga acgttctccg gcacgagaat gcattgcgaa tcggctcgcg
    20101 aaacaagttc gcgcagctcc tcctccaagg tcatgatctt cccgggcgca atgtggttgc
    20161 tcatgatgta tgccgcggcg gcggtgtcga aacgatcctg catccattcg gcatatgcca
    20221 gacgatagta ggcgaacgcg gcgtcgtcac ggtcgagcgc caccagcagc gcgttcaggc
    20281 atgcagcacg cgcggaatcc caatcctcgt cccgcgccaa ttgcacggcg agcttgagat
    20341 gcgccaacgg gtaggacggc gcgtacgcca ccatggcgtt caggtgcggc agcgcctcct
    20401 tggttccctt aagctgcgcg tacatgtcgg ccatttccat gtgcatgtag aacagattgt
    20461 cggggatgag cacggtatgc tcgtcgggcg tggcgaacaa gcgattgtat accacgcgtt
    20521 ccgcgtagga gttgaaatat cgcggcactc catcgccctg cgcatacagc gcatccatac
    20581 gcttgagcag gttctccgcg gactcgcatg cctgatccgg ccgcccggag aacagcatat
    20641 cgtgcatgcg cgcgcgttcg ttgtcaagct gggtcgcaag atcaagcttg accgttgggg
    20701 tatcgcgccc gtcgatcaac gcgccggcga tcgccgcgga ctgctcgctc agctccggat
    20761 cggcgatggt gtcgatgatg cgcgtggcct cctgcgcctt ggcgacggat ggcatggccg
    20821 tatccgaggc gagacggtgg aattcgctgt cggcacgctg catcacatcg acgcgttgga
    20881 tggatagtcc gaacgcattg cgcgcgccca atgcctgcgc cgcctccgga gtgaactcgt
    20941 gatcggccat ctccggttcc tcctgggagc cggctggtgc gaaaccacga tcacgcaggt
    21001 cgaagtcggg cacgatctgc ttgaggccgc cgttctcgtc aacatcgatt gtcgcattga
    21061 acatacggta cgtgtcttgg gggtgttcaa gcccgtcctg cctgatgcgt tcgaggaatt
    21121 cgtttcgggt gaaccggacc gtggccagcg tgcgtaccgt gggattgcgc ctgagcacgt
    21181 tcatcggatc gtcttgattg ccgtcatcgt cgcttttgaa tcctgccggc tgttcgcccg
    21241 ggtcggcgaa ggtggtctcg tcgatgtcga tgcctttgac cagatcctcg aaccgctgtt
    21301 ccatggaggc gtcgccggca tcggcatcgg attcgtcatg aggcgcgccg accggcggca
    21361 tgaacgagtc cgaacccatc tcggcaatgg atcgagccgc ggtacgggaa gggtcgccgt
    21421 gcatatcgcc gtccttgggc tcggccttgc tgccggtcgg tcccatatca ccggtatgca
    21481 tgcgctcgaa tgcgctcaac gcctcgctca tcatcgcctc gatgacggtg tcctgttcgg
    21541 ccacggcctc ctcaagaccg agcgagtcaa catgcagcga cacctcctgc acattgtcac
    21601 atgcgccaaa gctcagcaac gccagcatca ggccgacgcg cagattatag tcggcactga
    21661 gcgccgcacg ctcgcggtcc ctcaaggtga cccattgacc ggactgctcg tcatagcggg
    21721 tcgcgggcat catcgaaacg ccggccgtgg tgaagccgac cgccacgctc ccccgcgcaa
    21781 gatcagaccg caatgccgcg tcgaatcggt acggcaggcg caggctgcgt accagcagcg
    21841 acatggtctg ccgatacacc cattcggaat cggccggctt acccgtctcc ttcgaagctt
    21901 tgcgagccgt atcgaacagg atctgcatgg aactgtgccc cggttccggc gcatggtcga
    21961 cgcccagtgc cagcagggcc gggttcttca gcaggttcat gtcgatggcc gccgcctgct
    22021 cgcgcgtcac ggtctcctcc gtgggttcca atccaagacg cgagttatgt tcaagccacg
    22081 agctgaccat ggcgaatcgg ttgaggttgc cttcgatggc gagcgcccgc agcgctgggg
    22141 caagcgccag cgaggaatcc cagttgaaga agtatgcgcc ggaatagctg gaggtgtaca
    22201 ggtgcaacgg ttcggccccg tgcttggctt caagtccggg gatttcgtcg agtgccccgg
    22261 cttcgcgcat gagctcggcg aagtggtctt cgaggccgga gacgcgcatg ttgcgggcac
    22321 gggcttccag catgtcgcgt acggaacggc gtattgcgcc gatcggcgcc tcgcggttga
    22381 gtctgcggaa gatgttgccg gcgccgaagc cgatcagtgc gccgctcatt tgtggcagca
    22441 tgtatgcggc gaagaaggcg atggcgatgg catcgcggta ttcgaggttc tcccgcatag
    22501 tgccgggcag gttgcgacgc atctgttcga gccgatatct gccgtctttg cgtgaccatg
    22561 cggccagcca ggtcatacgg ccggtcatgt ctcgcccgac cacgccgccg tagtcgtggc
    22621 gttccttgga gaagatgaag cgcggttcga cgccttgcgg atccatgccg atctcgttgc
    22681 cgacgaagac gcgccccttg ccatcagcca cggcaatctg tgcgaaacga tcgcgcccgg
    22741 cgaacaggcc gagggagaat acgttgccct ggtaggttgt gctgggcagc tgcgcccagc
    22801 cgagggtcag tttgccgggg acctcgtcga agtcaaacat gtggcgtttg accagggggc
    22861 caagccgaac ggcatgttcg gcgaattggt cgatgatgcg ctgtgccggc tgattgtgtg
    22921 ccccggtgtt tgatgcatcg tgggattgcg caggcgcggt ggactcgctg ctggcgtgga
    22981 acctgttctt gtctgggcgc gggtcggacg tggcgccgaa cgggtcgacc atgcgcatgg
    23041 tcgcctttcc ctggcgcgac aaccgcgacg cccattgccg cgcgcgcccc aaggcatccc
    23101 cgaaggggtc g
//
