LOCUS       NZ_CP014241            21080 bp    DNA     circular CON 03-MAR-2024
DEFINITION  Bifidobacterium angulatum strain GT102 chromosome, complete genome.
ACCESSION   NZ_CP014241
VERSION     NZ_CP014241.1
KEYWORDS    RefSeq.
SOURCE      Bifidobacterium angulatum
  ORGANISM  Bifidobacterium angulatum
            Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
            Bifidobacteriaceae; Bifidobacterium.
REFERENCE   1  (bases 1 to 2064639)
  AUTHORS   Dyachkova,M.S., Klimina,K.M., Kovtun,A.S., Zakharevich,N.V.,
            Nezametdinova,V.Z., Averina,O.V. and Danilenko,V.N.
  TITLE     Draft Genome Sequences of Bifidobacterium angulatum GT102 and
            Bifidobacterium adolescentis 150: Focusing on the Genes Potentially
            Involved in the Gut-Brain Axis
  JOURNAL   Genome Announc 3 (4), e00709-15 (2015)
   PUBMED   26139716
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2064639)
  AUTHORS   Zakharevich,N.V., Averina,O.V., Nezametdinova,V.Z., Dyachkova,M.S.,
            Kovtun,A.S. and Danilenko,V.N.
  TITLE     Complete Genome Sequence of Bifidobacterium angulatum GT102:
            potential genes and systems to communication with host and bacteria
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 2064639)
  AUTHORS   Danilenko,V.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-FEB-2016) RAS, Vavilov Institute of General Genetics,
            Gubkina, Moscow 119991, Russian Federation
REFERENCE   4  (bases 1 to 2064639)
  AUTHORS   Danilenko,V.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2015) RAS, Vavilov Institute of General Genetics,
            Gubkina str., 3, Moscow 119991, Russian Federation
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: GS de novo assembler v. 3.0
            Genome Coverage                   :: 34x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 08:42:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,676
            CDSs (total)                      :: 1,608
            Genes (coding)                    :: 1,582
            CDSs (with protein)               :: 1,582
            Genes (RNA)                       :: 68
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 26
            CDSs (without protein)            :: 26
            Pseudo Genes (ambiguous residues) :: 0 of 26
            Pseudo Genes (frameshifted)       :: 7 of 26
            Pseudo Genes (incomplete)         :: 19 of 26
            Pseudo Genes (internal stop)      :: 4 of 26
            Pseudo Genes (multiple problems)  :: 3 of 26
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:36:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1354723
            Orig. end                         :: 1375803
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014241.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21080
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21080
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21080
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11080](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11080)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     ncRNA           complement(199..572)
                     /db_xref="RFAM:RF00010"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="Bang102_RS05350"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="Bang102_005350"
                     /product="RNase P RNA component class A"
     gene            complement(199..572)
                     /gene="rnpB"
                     /locus_tag="Bang102_RS05350"
                     /old_locus_tag="Bang102_005350"
     misc_feature    592..605
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.25"
                     /tool="antismash"
     misc_feature    594..607
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.01"
                     /tool="antismash"
     misc_feature    complement(595..608)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.21"
                     /tool="antismash"
     misc_feature    664..677
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.83"
                     /tool="antismash"
     gene            752..1414
                     /gene="raiA"
                     /locus_tag="Bang102_RS05355"
                     /old_locus_tag="Bang102_005355"
     CDS             752..1414
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_component="GO:0022626 - cytosolic ribosome [Evidence
                     IEA]"
                     /GO_function="GO:0045182 - translation regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0009386 - translational attenuation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="raiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012577316.1"
                     /locus_tag="Bang102_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005355"
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="WP_003826022.1"
                     /transl_table=11
                     /translation="MEIVITGRHTQIKQRFRDVVESKMNRVTAIAPDAQRAQIVLSHEG
                     NPRQADTAKRVEITIIAGSTVVRAEASSADEFSALDMALDKLTLRLRRTRDRRKDHRRG
                     YENPVPVDLGVIEPEPAAAEEEVHEDVENSPAAAVASDLGPGESVEVQVGDTPIVIRRK
                     LHIAEPMTIDEALYEMELIGHDFFLFVNKETGRPSVVYHRHGWSYGVFEIDTPEHVN"
     gene            1629..4478
                     /gene="secA"
                     /locus_tag="Bang102_RS05360"
                     /old_locus_tag="Bang102_005360"
     CDS             1629..4478
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006605 - protein targeting [Evidence IEA]"
                     /GO_process="GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /GO_process="GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /gene="secA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013410781.1"
                     /locus_tag="Bang102_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005360"
                     /product="preprotein translocase subunit SecA"
                     /protein_id="WP_045920150.1"
                     /transl_table=11
                     /translation="MVDIVDKALRMGEGRQIKKLEGVAKAVNALEDEISALSDEELKGQ
                     TAKFKQQLENGKSLDELMPEAFATVREASKRVLGQRHFDVQLMGGAALHWGNIAEMKTG
                     EGKTLVATLPSYLNALEGKGVHVVTVNDYLASYQSEIMGRIYRFLGMSVGCIITNQKPP
                     ERRKQYNADITYGTNNEFGFDYLRDNMAWEKADLVQRGHHYAIVDEVDSILIDEARTPL
                     IISGPAEGDVTRWYREFAKLVVKLTRDEDYEVDEKKKVVGILDPGITKVEDFLGIDNLY
                     EPNNTALIGYLNNAIKAKELFLRDRDYVVTHGEVLIVDEHTGRVLPGRRYNEGLHQAIE
                     AKEGVEVKAENQTFATITLQNYFRMYDKLAGMTGTAETEAAEFMSTYKLGVLPIPTNKP
                     MQRIDQEDLIFRTKKEKLAAIVKDVAKRHAAGQPVLLGTASVESSEVVSTLLDVAKIPH
                     QVLNAKQHDREAAVVAVAGRKGAVTVATNMAGRGTDIMLGGNVEFLADAKLKADGYSPE
                     DTPDEYEKRWPGVLAEIKEQVKDEHQEVVDLGGLYVLGTERHESRRIDNQLRGRSGRQG
                     DPGESRFYLSLEDDLMRLFNTQLVARVMAKGLPEGEPIAAKSVSKGVRTAQKARESQNF
                     EIRKNVLKYDDVMNKQRTVIYAERQAVLKGEDIHDDILRFISDTVMSYVKGANNSSDKP
                     AEWDWEGLFKALNSVIPIDVTVEEAKKAAEGKKGEKAAEAVRDVIVADADAAYSGFEDK
                     LGGEGLRQLERRVVLAVLDRKWREHLYEMDYLKDGIGLRGMGQRDPLVEYQREGYQMYN
                     SMIEAIKEETVQLLFHVDIQQVAETEDLESEADEDAAVNATQAELGIASSASADTEAEG
                     PDEDGDEVTRDEDGNPVIVGPAPVSHAEGKVPASKQPKSEELKTPWADGRTFPGTGKNA
                     PCPCGSGRKYKMCHGQNEQ"
     misc_feature    complement(4590..4604)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.41"
                     /tool="antismash"
     misc_feature    4591..4605
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 23.51"
                     /tool="antismash"
     misc_feature    complement(4610..4623)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     gene            5159..6211
                     /gene="trpD"
                     /locus_tag="Bang102_RS05365"
                     /old_locus_tag="Bang102_005365"
     CDS             5159..6211
                     /EC_number="2.4.2.18"
                     /GO_function="GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826030.1"
                     /locus_tag="Bang102_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005365"
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="WP_045919916.1"
                     /transl_table=11
                     /translation="MAEITWKSILAKLVGGDHLSAEESEWFVDDLMNGNANPAAVGAAL
                     ATQQQLGLTADEVRGAAKAMVSHAVPLNIEGETTDIVGTGGDGASTVNLSSMGAVIAAA
                     TGVKVVKHGNRAASSECGTADCFEELGLPLDLTAEQVARVGNECGIAFAFARVFHPAMR
                     FVGPIRAALGVPCVFNVLGPLTNPANPKHMAIGCANRAMSPIMAAVYAANGQTGMVYTS
                     SEGLDEMAPTGPISVWEFRNGKVSETEFDPTVELGLAKITVEDLKGGKPAVNAQAMRDL
                     LAGKDVPFRSTALLNAASAIVADGHQVPADVTLAERFKAAYAIAEESVDSGKAEALLNK
                     WIATAQSVKG"
     gene            complement(6389..6946)
                     /locus_tag="Bang102_RS05370"
                     /old_locus_tag="Bang102_005370"
     CDS             complement(6389..6946)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014697929.1"
                     /locus_tag="Bang102_RS05370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005370"
                     /product="DUF308 domain-containing protein"
                     /protein_id="WP_045919915.1"
                     /transl_table=11
                     /translation="MTDLNNTNAGDERPQHTPDGENQPNDLDAAWAAFEAEHQDDLNDV
                     AESRNAKRFEKHAQRKEKETLLSVDDLTADSFAKTGASHGPRDFTGSSWLDADDVMDRY
                     GDDFVPPNPKIGRVRFSKLVFWILLVAGILGAIASVFLPAYTGVLGVIAGICVIVGGAG
                     LLAQHKGFSQTRTDYFDDGARV"
     misc_feature    6947..6962
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 21.05"
                     /tool="antismash"
     gene            6994..7707
                     /locus_tag="Bang102_RS05375"
                     /old_locus_tag="Bang102_005375"
     CDS             6994..7707
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826034.1"
                     /locus_tag="Bang102_RS05375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005375"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_045919914.1"
                     /transl_table=11
                     /translation="MLYWFFVNGFGFIARHRLGPAVTGLENVPREGGAIIAANHLAVID
                     DALIPITCPRMVHFMGKAEYFEGKGLKGKFKKWWFTSVGVFPVDRSGGNKSLGALEHAR
                     EIIEDGHLFGIHIEGTRSPDGRLYKGHTGAARLALETGCPIIPVAIIGSDKLQPVGTVI
                     PKKGKTQVLYGKPIMVEKKSADEITHDDLRSLTDAVSEAIRKMSGQEYVPEYAQKVKAR
                     LKEEAAKAESQQPQE"
     gene            complement(7819..9942)
                     /locus_tag="Bang102_RS05380"
                     /old_locus_tag="Bang102_005380"
     CDS             complement(7819..9942)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826037.1"
                     /locus_tag="Bang102_RS05380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005380"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_045919913.1"
                     /sec_met_domain="Pkinase (E-value: 3e-50, bitscore: 167.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEDASPQGQLIDGRYHVVREIAQGGMATVYEAIDERLNRTVALK
                     VMHTQLAQGAHREQFIERFRREAQSAAQIANPHIVQVYDTGEFNGLAYLVMEYVHGVNL
                     RYEMNQQGTFTVRETLRIIGETLEGLAAAHQVHVVHRDIKPENIMLNDRGRVQITDFGL
                     AKVASAATLSSTGMLLGTAAYLPPETIEHNEATPQGDLYAVGIMAWEMLTGSVPFISDN
                     PVTLVFKHVHEDVPSVALQCPGIDPAVARFIGHLTQRSVQARPADAGAALLELKQLCNS
                     LEPNAWMYRKPSSTTDTAQTGTAPVPAPPAPPVQARSEESVPDATTSPMRPNATTPISE
                     GSTQVLNAPDRSDGTATATTAMPANGNGASKETPAASSKRGRKALIIAIISLVVAVACA
                     GGAWWYFLGPGSYWKIPKPADVTCNADSACSLEGASWKQYERVLKNAGIPYSATKDYSD
                     TVDEGHVISATVAGSPVAVDSHVSMRQQQKVNVVVSKGMRMSTIPDDILDTTSANGKSP
                     LEALKHAGFTNIKHDTGKDEYSLTAPEGTALSITPEPGTTLKHNAKVTVSLSKGPMPVT
                     MPDIADRAKDEASRALDDLKLKATFTEEFSDTVAAGEVISTSVPKDTQLHWGDAVEVMV
                     SKGPETVTLPNVVGKTYDEASAMLKALGLDVKKSAPLGDLTHVVRLQSPNAGDQVRVRD
                     SDGNKTVVTLTVV"
     misc_feature    complement(9988..10003)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.98"
                     /tool="antismash"
     gene            complement(10001..11080)
                     /locus_tag="Bang102_RS05385"
                     /old_locus_tag="Bang102_005385"
     CDS             complement(10001..11080)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826039.1"
                     /locus_tag="Bang102_RS05385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005385"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_045919912.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.1e-47, bitscore:
                     157.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKTDADRSNIESRIVSLVDRWSAMPMEAEMPEACRHVVDAVSRQ
                     AISSSEGGKRLRALLMLAAYDAFDGHADTRNAMLDVACALEVFQTAALVHDDIIDDSDL
                     RRGKPSAHRALETDTGSPAIGRGLGLMLGDLLATVCIDIVNEAAALLPHATALTSAFLN
                     MQREVEIGQILDLAVEQAPLQDAEALANASLNVFRWKTASYTTIAPIELALLGSGAAPG
                     QARERALAIGKPLGLAFQLEDDLIDVIGSSRATGKPVGGDIREGKRTVLLADAIAHADC
                     AARDELIAMFEASSRSESDVSRAIGLFQSTGAIERSRQRIGDLWDESVQAIRECKLEQS
                     HETALLETCARFVPDIAKS"
     gene            11225..12040
                     /locus_tag="Bang102_RS05390"
                     /old_locus_tag="Bang102_005390"
     CDS             11225..12040
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Bang102_RS05390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Bang102_005390"
                     /product="DUF4192 family protein"
                     /protein_id="WP_052946479.1"
                     /transl_table=11
                     /translation="MEDGGGNGIEEDDMTTNRMESAAGQTNDRADGHGDADSAGRVLEE
                     RIVENRCRHGEGEGSVPSADRAACEEFFDALEPVCEHAADEMRKRLQQGRRQYGPSRAD
                     GDWMREPLQVWLCRLDQGMIDLDEVMLPLAVGINEVLAMRDALILSVVGDSTMRDPQML
                     MDIVRTPHAGHVVMAVHKALSAEFDDRDGPDRDRCRTAVLMLAAMAKVMPEPMKVQPLA
                     IISYILWWTGDSRAEDYALSCLAIDEECSLAAIVLKSVSNGLYPACCGG"
     gene            12208..13656
                     /locus_tag="Bang102_RS05395"
                     /old_locus_tag="Bang102_005395"
     CDS             12208..13656
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007055162.1"
                     /locus_tag="Bang102_RS05395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005395"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_045919911.1"
                     /transl_table=11
                     /translation="MATKSTTAAENTEQVQDEAKVVSAKKASATRKTAAAKKTAAKKTA
                     KSGEGTGSVKKKSAATKSTKNSKTKKRSEEDLDEVDEFDEDADLDDAKDEDLDVDDVDD
                     LDGINGESDDDDDDYDDDDDDDDEEEDDKSDAPDISKQKGAFVVSDDDDDDEDVKPRRR
                     RGKIGNPKRRVVTAGATADPVKDYLKQIGRVSLLNAEQEVDLSERIEAGLYAQHLLDTE
                     GDTMDFKRKRELKWAANDGKKAKDHLLEANLRLVVSLAKRYTGRGMLFLDLIQEGNLGL
                     IRAVEKFDWKKGFKFSTYATWWIRQAITRAMADQARTIRVPVHMVEVINKLSRVQRQML
                     QDLGREPTPDELARELDMPVEKVQEVQKYGREPISLHTPLGEDGDSEFGDLIEDTDAIA
                     PSDAVAFSLLQDQFKQVLETLSPRESGVIKMRYGLEDGQPKTLDDIGRVYGVTRERIRQ
                     IESKTMSKLRHPSRSQTLRDFLDQ"
     gene            13735..16029
                     /locus_tag="Bang102_RS05400"
                     /old_locus_tag="Bang102_005400"
     CDS             13735..16029
                     /EC_number="5.6.2.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008783099.1"
                     /locus_tag="Bang102_RS05400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005400"
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="WP_045919910.1"
                     /transl_table=11
                     /translation="MAKEDYGAKDLTVLEGLDAVRKRPGMYIGTTDSQGLMHCLWEIID
                     NAVDEALAGFCNAIVVTLHTDGSITVADNGRGIPVDKEPKTKLSGVEVVLTKLHAGAKF
                     GNSSYNAVGGLHGVGSSVVNALSSRLDIEVDRDGKTYHMAFHQGHPGVYTDTDPEHPSP
                     DAPFKRTRKNKPTELDIIGKVPPKRTGTRIRYWADPEIFNKTAEFSYEQLVDRVRQTSF
                     LVPGLKITVIDENIAQEPAPGEPDHEMTSVPEGVGAGETVTADAASAVGESDSAQTQGD
                     EDLALNEAETIADGAFGTQVDHPRVAEFLHNGGVKDFVDYLSKGEPVSDIWRIQGEGTY
                     EEETQAVGANGELHAEKITRTCGVDIALRWVNGYDTVMRSFVNIIETPGGGTHVDGLMN
                     SVTRQIRKAVEANARKLKVNLKDSNMKVERDDIMAGLVAVVTVRIAEPQFQGQTKDVLG
                     TAQVKPIVTRMSDKQFGEMITGSKRGYKEQSNRVLEKIVGEMHARVQSRKAKEVTRRKN
                     ALESASMPAKLSDCQPGNDDVAELFIVEGDSALGTAKAARNAGFQALLPIRGKILNVQK
                     ASITQMLSNKECAAIIQVVGAGSGQSFDIEQSRYHKVIMMTDADVDGAHIRILLLTLFY
                     RYMRPLIENGYVYAAVPPLHRIALTGSHKGEFIYTYSDDELAGKLAELDRKHIGYNDDI
                     QRYKGLGEMDADQLADTTMDPRTRMLRRIRMEDAEQASEIFSLLMGDDVPPRKAFIVEN
                     ADDFDRSKIDT"
     gene            complement(16161..17420)
                     /locus_tag="Bang102_RS05405"
                     /old_locus_tag="Bang102_005405"
     CDS             complement(16161..17420)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826046.1"
                     /locus_tag="Bang102_RS05405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005405"
                     /product="hypothetical protein"
                     /protein_id="WP_045919909.1"
                     /transl_table=11
                     /translation="MGSISHERIDARHDAEELSDYVNNGWLRTGEFDGPTILWNHLIRE
                     ASEHDAENRNDAPVAPLSDADNVIGMPMQWYFDSIAAIVPTAERTETGVEMPRADMPTF
                     HLDSQALSGVDAVVGNALVSTRWVDAVGNLAKALEMTAKFVGNVADRDNEGFDYLKDLI
                     QNVRVYMDAVACNADPMTGEQALRMITTVACNDDFRLNAMQMVELLSCSLSFAQWDDTR
                     MFAYDALNKAVASMAEFSSRSTQTSGQTGTVDAADDIKLSAADLDNLVSLDPSLLTERE
                     LAATACHQFDHAVQFLRHDLMRISGDAEAADAFLREHNTIEPLADTYAARLIASERWED
                     LIDFTNRVEQANANQSMVMFPEEVVPYEWETLREAALEALGRGDELVAMYRSRLEDNYD
                     PNTELNQYKLDLWLNRADNQ"
     misc_feature    complement(17520..17540)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.06"
                     /tool="antismash"
     misc_feature    17731..17743
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     misc_feature    17870..17886
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.56"
                     /tool="antismash"
     gene            18065..18970
                     /locus_tag="Bang102_RS05410"
                     /old_locus_tag="Bang102_005410"
     CDS             18065..18970
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826048.1"
                     /locus_tag="Bang102_RS05410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Bang102_005410"
                     /product="DUF3152 domain-containing protein"
                     /protein_id="WP_045920148.1"
                     /transl_table=11
                     /translation="MVSALNPNASSNLDAKQVFRIRRTVVFSGIAAVVLIVAVIVAVSV
                     HANRSAQADKAGTVVNAQTSKTKQSPSAKATKKTTAGKTAAENSSAKKTQEQSDTSSSS
                     TDETKRQVEALAASISDEESATIKAKADETAHNSGKPVTQYTYCIAGKGNVGALDGFAN
                     TVYRVLNDPRGWPRAGATFVKGDGDACNFTVVLSEAKYMQTFDSGCSAEYSCRVGDNVI
                     INLDRWNGGIGNWMEAGGNLARYRTMVINHEVGHALGHIDNETTCAGAGKPAPLMQEQS
                     MHLDGCTVNEWPLDDELWRS"
     misc_feature    18994..19008
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.46"
                     /tool="antismash"
     misc_feature    complement(19430..19445)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.53"
                     /tool="antismash"
     misc_feature    19693..19708
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.29"
                     /tool="antismash"
     misc_feature    20960..20976
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 20.95"
                     /tool="antismash"
ORIGIN
        1 ttttggtctg cgggagggcg caaaggccat gacgccgaca cgctgcggcg tgtcgcgcat
       61 gagctgttag atgactgact ccggtgtgtc gcggcgtgtc gtgtgcgggc ggaagcacga
      121 ggcgtgagtc tgaccaagtc caggccgcgc tttgcggcaa tatcaacgct gacatgacag
      181 agatcaataa aagcaaaata agtgagacct cttatacccc gggttctgtc gtgtgctggg
      241 cacacggatg gccatccatc tcgacccaac gttgccgctg ggctctagca gcctacccga
      301 tggcacgagc gagcagccct taccgccatc tgtttggcct tgctcccgat gaggcttgcc
      361 atgcggtcca ctgttaccag ggacccggtg gtctcttacg ccgccgtttc acccttacct
      421 tccggccgaa gccgaaaggc ggtctattct ctgttgcgct atctctcagg tcgccctggg
      481 cggacgttat ccgccatcgt gctctatgga gcccggaagt tcctcaacca cgcatgcaaa
      541 gcatgcccgg tcgcggccat caagaggtct caaacacaca actataccag catttttgaa
      601 tataaaaaac caaggaaatt catagacatt tatgtggttt gctcccgccg tttcccaaaa
      661 gctcgtttac aataaaacgt acccggtcag tgaagacacg gctggaacgc aaatagcggg
      721 taatgccgct tgagtttact aggaggtcca catggaaatc gtcattaccg gacgtcacac
      781 tcagatcaag caaaggttcc gtgatgtcgt tgagagcaag atgaatcgtg tgaccgctat
      841 cgcccccgat gcgcagcgtg cccagattgt gctgtcgcat gaaggcaacc cacgccaggc
      901 cgataccgcc aagcgcgtgg aaatcaccat tatcgcaggc agcaccgtgg tgcgtgcgga
      961 ggcttcctcc gcggacgagt tcagcgcact tgacatggcg ctcgacaagc tgaccctgcg
     1021 tctgcgccgt acccgcgatc gtcgcaagga ccatcgtcgc ggctacgaga acccggttcc
     1081 ggtcgatctg ggtgtcatcg agccggagcc tgcagctgct gaggaagagg tccacgagga
     1141 tgtcgagaac agccccgcag cagccgtcgc ttccgatctt ggccccggcg aatccgtcga
     1201 agtccaggtt ggcgataccc cgatcgtgat tcgccgtaag ctgcacatcg ccgagccgat
     1261 gaccattgat gaggcgctgt acgagatgga actgatcggc catgatttct tcctgttcgt
     1321 gaacaaggag accggtcgtc cgtccgtcgt ctaccatcgt cacggctgga gctacggtgt
     1381 gttcgagatc gacaccccgg agcatgtgaa ctgacgatca ctcatcatca atcatgagtc
     1441 gatgaagttg gggcccgcgc cgtccgcata cggtgtgggc cccaactcat ggccgattgt
     1501 ctgttatttg gcgcggcaat ggcgctgtta tcggcaatgt cgcgtaagat aactggcagt
     1561 gtgcccgcac atcatggcag agaatgccgc acgggcacgg aatatcgcga ccgacacagg
     1621 agcagaacgt ggtagatatt gtcgataagg cactgcgcat gggcgaaggc cgtcagatca
     1681 agaagcttga gggtgtcgcc aaggccgtga acgctcttga agatgagatc tcggcgcttt
     1741 cggacgaaga actcaagggg cagaccgcta agttcaagca gcagctggag aatggcaaga
     1801 gcctggatga actcatgccg gaggcattcg caacggtgcg cgaggcttcc aagcgcgttc
     1861 tcgggcagcg ccatttcgat gtacagctca tgggcggcgc ggccctgcac tgggggaaca
     1921 tcgccgaaat gaagacgggc gaaggcaaga ccttggtcgc caccctgccg agctatctga
     1981 acgccttgga gggcaagggc gtgcatgtgg tcaccgtgaa cgactatctg gccagctacc
     2041 agagcgagat catggggcgc atctaccgtt tcctgggcat gagcgtcggc tgtatcatca
     2101 ccaatcagaa gccgccggag cgtcgcaagc agtacaatgc cgacatcacc tacggcacca
     2161 acaacgagtt cggcttcgat tatctgcgtg acaacatggc gtgggagaag gccgatctgg
     2221 tgcagcgcgg ccatcattac gccatcgtcg atgaggtcga ttccattctt atcgatgagg
     2281 cgcgtacccc gcttatcatc tccgggccgg ccgagggcga cgtcacccgc tggtaccgcg
     2341 agttcgccaa gctggtcgtc aagctgaccc gtgacgagga ctacgaggtc gacgagaaga
     2401 agaaggtcgt cggcattctc gatccgggca tcaccaaggt cgaggacttc ctgggcatcg
     2461 acaacctgta cgagccgaac aacaccgccc tgatcggcta tctgaacaac gccatcaagg
     2521 ccaaggagct cttcctgcgt gaccgtgact acgttgtcac ccatggtgag gtgcttatcg
     2581 tcgacgagca caccggtcgc gtgctgccgg gccgccgcta caacgagggt ctgcaccagg
     2641 ccatcgaagc caaggaaggc gtggaggtca aggccgagaa ccagaccttc gccaccatca
     2701 ccctgcagaa ctacttccgt atgtacgaca agctcgcagg catgaccggt accgcagaga
     2761 ccgaggccgc cgagttcatg agcacctata agctgggcgt gctgccgatc cccaccaaca
     2821 agccgatgca gcgcatcgac caggaggatc tcatcttccg caccaagaag gaaaagcttg
     2881 ccgccatcgt caaggacgtg gccaagcgcc atgccgcagg ccagccggtg ctgctgggta
     2941 ccgcaagcgt cgaaagctcc gaagtcgtgt ccacgctgct tgatgtggcc aagattccgc
     3001 accaggtgct caacgcgaag cagcatgaca gggaagccgc cgttgtggca gtcgccggcc
     3061 gcaagggcgc cgtcaccgtg gctaccaaca tggcaggccg tggtaccgat atcatgctcg
     3121 gcggcaacgt cgaattcctc gcggatgcca aactcaaggc tgacggctac tccccggagg
     3181 acacccccga cgagtacgag aagcgttggc cgggcgtact ggccgagatc aaggagcagg
     3241 tcaaggacga acaccaggag gtcgtcgatc tgggcggtct gtacgtgctc ggcaccgaac
     3301 gccatgaatc ccgtcgtatc gacaaccagc tgcgtggtcg ttccggtcgc cagggcgatc
     3361 cgggcgaatc ccgcttctac ctgtctctcg aagacgatct gatgcgtctg ttcaatacgc
     3421 agctggtcgc ccgcgtcatg gccaagggtc tgcccgaggg cgagccgatt gcggccaaga
     3481 gcgtgtcgaa gggcgtgcgt accgcgcaaa aggcccgcga atcgcagaac ttcgagattc
     3541 gtaagaacgt gttgaagtac gacgatgtga tgaacaagca gcgtaccgtc atctacgccg
     3601 agcgtcaggc ggtgctcaag ggcgaagaca tccacgacga catcctgcgc ttcatctccg
     3661 acaccgtgat gagctacgtc aagggtgcga acaacagttc cgacaagcct gccgagtggg
     3721 attgggaagg tctgttcaag gcattgaaca gtgtgattcc gatcgacgtg accgtcgagg
     3781 aagccaagaa ggccgccgaa ggcaagaagg gcgagaaggc cgccgaagcg gtacgcgacg
     3841 tgatcgtcgc cgacgccgac gcagcgtatt ccggcttcga agacaagctg ggcggcgaag
     3901 gtctgcgcca gcttgaacgc cgtgtggtgc ttgccgtgct cgaccgcaag tggcgtgaac
     3961 acctgtacga gatggactac ctcaaggacg gcatcggtct gcgcggcatg ggtcagcgcg
     4021 atccgctggt cgaataccag cgcgaaggct accagatgta caactccatg atcgaggcga
     4081 tcaaggagga gaccgtgcag ctgctcttcc atgtggatat ccagcaggtc gccgaaaccg
     4141 aggatcttga atccgaagcc gatgaggatg cggccgtgaa cgccacccag gccgagctcg
     4201 gcatcgcgtc atccgcttcc gccgataccg aggcggaagg ccccgacgag gacggcgacg
     4261 aggtcacccg cgacgaggac ggcaatccgg tcatcgtcgg tccggccccc gtcagccacg
     4321 ccgaaggcaa ggttccagcc agcaagcagc cgaagagcga agagctgaag accccgtggg
     4381 ccgacggtcg tacgttcccc ggcaccggca agaacgctcc gtgcccctgc ggttccggtc
     4441 gcaagtacaa gatgtgccac ggccagaacg agcagtgatc aagctatcgg gccgattccg
     4501 ataacctgtc gattgcgttg agggctgcac ccattgaaat gggtgcagcc ctcaattcga
     4561 ctgtgcatgc tctatgccac agtgaacccc tgggagcgcg cacattccgg caacatggat
     4621 gcccactgtt cgatgacatc gacggaattg ccgccagaaa ccagtgacgg cacaagcgaa
     4681 tcacgatagg cagtgccgag ctgtgtggcg aacggcagtg tgattgcaat atgatcggaa
     4741 gcgcctccaa cccggaacgg tgcggctcca aagggttgtc gaatacttga gatgcgtccc
     4801 ccatgccctc ctcgattacg cgccattccg gtcctagaag cttggctaaa cgtcccgttc
     4861 agcgtatgtt gaaggggtgc cttgttccag gtttcgccgg gttggtaccg aacgtattgg
     4921 aatcaccgaa gcacagtaca ttgttcatgg catggccctt tcgaatcgac tgatgggcag
     4981 tgattgccac tgtaatatcg acgaaaccgt cttcctgatg gattgccatg gattgccatg
     5041 acattaccgg caggggcggt gttcgtgatg cggacgttca tcggcgcgga aataccgaat
     5101 cgttacaatt aggcgacaaa tcatacaaca ggcgtattgg agcgccaagg agggcattat
     5161 ggctgaaatc acatggaagt cgattctcgc caagctggtc ggaggggacc acctgagcgc
     5221 ggaggaatcc gagtggttcg tcgatgacct catgaacggt aacgccaatc cggctgccgt
     5281 gggcgcggcg cttgccaccc agcagcagtt gggattgacc gccgacgaag tgcgtggcgc
     5341 ggccaaggcc atggtctcgc atgcggtgcc gctgaatatc gaaggggaga ccaccgatat
     5401 cgtgggcact ggtggcgacg gcgcctccac ggtgaatctg tcatccatgg gagcggtgat
     5461 tgccgcggcg accggcgtca aggtggttaa gcatggcaat cgtgccgcgt cctccgaatg
     5521 cggcaccgcc gactgcttcg aggagcttgg tctgccactt gatctcaccg cggaacaggt
     5581 ggctcgggtc ggcaacgaat gcggcatcgc cttcgccttc gcgcgtgtgt tccaccccgc
     5641 catgcgtttc gtcggaccga ttcgcgcggc attgggtgtg ccttgcgtgt tcaacgtgct
     5701 cggtccgctc accaatccgg ccaatccgaa gcatatggcc atcggttgcg ccaatcgtgc
     5761 catgagcccc atcatggccg cagtctacgc ggcgaacggg cagaccggca tggtctacac
     5821 ctccagcgaa ggattggacg agatggcacc gaccgggccg atctccgtat gggagtttag
     5881 aaacggcaag gtcagcgaaa ccgaattcga tccgactgtg gaactcggcc ttgccaagat
     5941 caccgtagag gatctgaagg gcggcaagcc ggcggtcaac gcccaggcca tgcgcgatct
     6001 tcttgccggc aaggacgttc cgttccgttc cacggcattg ctcaatgccg catccgccat
     6061 tgtggcggac ggtcatcagg tgcccgctga tgtcacgctt gccgaacggt tcaaggcggc
     6121 ttacgccatt gccgaggagt ccgtggattc aggcaaggcc gaggcgctgc tgaacaagtg
     6181 gatcgcaacg gcgcagtcgg ttaagggctg aacgccgcat ccgccacgcc ggtatcgcgt
     6241 aagcatgcgg tatggtgcga caaaccgcgg atgaccaata gcaatgatgg ggttgtctcc
     6301 aactggaggc gaccccatca ttcgttccgg tgcaattcag gtgctgctct gtatgccgcc
     6361 atggaagtgg acggaggagc ggccgacgtt atacgcgcgc accgtcatcg aaataatcgg
     6421 ttctcgtctg ggaaaagccc ttatgctgcg caagcagtcc cgcaccaccc acgattacgc
     6481 aaatgccggc gatgacgccc agaacaccgg tatatgcggg aaggaacacg gaggcgatgg
     6541 cgccaagaat gccggcgacc agcagaatcc agaacacgag ttttgagaaa cgcactcgac
     6601 cgatcttcgg attcggcggc acgaaatcgt caccataccg atccattacg tcatcggcat
     6661 ccagccagct ggaaccggtg aagtcgcgcg ggccgtgaga ggcgccggtc tttgcgaacg
     6721 aatccgcggt cagatcgtcg acgctcagca gcgtctcctt ctccttgcgc tgcgcatgct
     6781 tttcgaaacg cttcgcgtta cgggattcgg ccacatcgtt cagatcatcc tgatgctcgg
     6841 cttcgaatgc cgcccaagcg gcgtccagat cgttcggctg gttctcgcca tccggcgtgt
     6901 gttgtggccg ctcgtcaccc gcattggtat tgttaaggtc agtcatatgt accactgtaa
     6961 accacggtga gcatcgaatg gaaggaacgc caagtgctgt attggttttt tgtgaacgga
     7021 ttcggtttca tcgcccggca tcgccttggc ccggccgtta ccggtttgga gaacgtccct
     7081 cgtgaaggcg gagcgattat cgcggcgaat catctggccg tcatcgacga cgcgctgatt
     7141 ccgatcacgt gcccgcgtat ggtgcatttt atgggtaagg ccgaatactt tgagggcaag
     7201 gggctcaagg gcaagttcaa gaagtggtgg ttcacttcgg taggcgtgtt tcccgtggac
     7261 cgttccggtg gcaataaatc gctgggcgcg ttggagcatg cgcgggagat catcgaagac
     7321 ggtcatctgt tcggtatcca tatcgagggc acgcgcagcc ctgacggacg cttgtacaag
     7381 gggcacaccg gtgccgcgcg actggcgttg gaaaccggtt gcccgattat tcccgtggcg
     7441 attatcggct cggacaagct gcagcctgtg ggtacggtca ttccgaagaa gggcaagacc
     7501 caggtgctgt atggcaagcc gattatggtg gagaaaaaat ccgccgatga gatcacgcat
     7561 gatgatctgc gctcgttgac cgatgccgtc agcgaggcga ttcggaagat gagcggacag
     7621 gaatatgttc ccgaatacgc gcagaaggtc aaggcgcggt tgaaggaaga ggctgctaaa
     7681 gccgagagcc agcagccgca ggaataattc cgcggccatg gcgtggggct gaaactgccg
     7741 gttgagccaa ggggatacga gcgaagaaag gctcgtatcc ccttgactat atgtggagac
     7801 gttgcaaaag ccgtcgcatc agacgacggt cagcgtcacc acggttttgt tgccgtcgct
     7861 gtcgcgcacg cgcacctgat cgcctgcatt ggggctttgc agacgaacga catgcgtcag
     7921 atcgcccaac ggcgctgatt tcttcacatc caagccgagc gccttcagca ttgcgctggc
     7981 ctcatcgtac gttttgccaa ccacattcgg cagtgtcacg gtttccgggc ccttggagac
     8041 catgacctcc acggcatcgc cccagtgcag ttgcgtgtcc ttgggcacgg atgtcgagat
     8101 tacctcgccg gcggcaacgg tatcgctgaa ttcctcggtg aacgtcgcct tcaatttcag
     8161 atcgtcaagt gcccgcgacg cttcgtcctt cgcgcggtct gcaatatccg gcatggtcac
     8221 cggcatgggc cccttgctca acgagacggt aacctttgcg ttgtgcttga gcgtggtgcc
     8281 tggctccggg gtgatggaca atgccgtgcc ttcgggggcg gtcagtgaat actcgtcttt
     8341 gccggtgtcg tgtttgatat tggtgaatcc ggcatgtttc agcgcttcca gcgggctttt
     8401 gccgttggcg ctggtggtat cgagaatatc gtcgggaatc gtcgacatgc gcatgccttt
     8461 ggaaaccacg acattcacct tctgctgctg tcgcatgctc acatggctgt cgaccgcgac
     8521 gggagagcct gccaccgtgg ccgaaatcac atgcccctca tcgacggtat cgctgtagtc
     8581 cttggtggcg ctgtagggga tgccggcatt cttcaacacg cgctcatact gcttccagga
     8641 ggcgccttcc aaggagcatg ccgaatccgc attgcaggtc acatcggccg gcttggggat
     8701 cttccagtag cttcccggcc ccaggaaata ccaccatgcg ccgcccgcgc acgctacggc
     8761 tacgaccagt gagatgatgg cgatgatcag cgctttcctc ccgcgcttcg aggaagcggc
     8821 gggggtttcc ttcgatgcgc cgttgccgtt ggcgggcatg gcggttgtgg cggttgccgt
     8881 gccatcgctt cgatccggtg cgttcagcac ctgcgtggac ccctcgctaa tgggcgtggt
     8941 ggcgttcgga cgcatcggtg aggtcgtcgc gtcaggcacg gattcctcgg atcgcgcctg
     9001 tacgggaggt gccggtggag cgggcacggg tgccgtgccg gtctgtgccg tatcggtggt
     9061 cgaagatggc ttgcgataca tccatgcatt cggctcaagc gaattgcaca actgtttgag
     9121 ctcgagcagc gcagcacccg catccgccgg gcgggcctgc acggatcgct gggtgagatg
     9181 cccgatgaac cgggcgaccg ccggatcgat gccggggcat tgtaacgcca cggacggcac
     9241 atcctcatgc acatgcttga acaccagcgt caccggattg tcggaaatga acggcaccga
     9301 gccggtcagc atctcccatg ccatgatccc cacggcatac aggtcgccct gaggcgtcgc
     9361 ctcattgtgc tcgatggtct ccggaggcag ataggcggcg gtgcccagca gcatgccggt
     9421 ggacgagagc gtggccgccg acgccacttt ggccagaccg aaatcggtga tctgcacacg
     9481 gccgcgatcg ttcagcatga tgttctcggg tttgatgtcg cgatgcacca catggacctg
     9541 atgcgccgcg gcaagccctt cgagggtctc gccgatgatg cgcagcgtct cgcgcacggt
     9601 gaaggtcccc tgctgattca tttcatagcg cagattcacg ccatgcacgt attccatcac
     9661 cagataggca agaccattga attcgccggt gtcatacacc tgcacgatat gaggattggc
     9721 gatctgcgcc gccgactgcg cctccctgcg gaaccgttcg atgaactgtt cgcgatgcgc
     9781 gccctgcgcc aactgcgtat gcatcacttt cagcgcaacc gtgcggttca gtcgttcgtc
     9841 gatcgcctcg tataccgtcg ccatgcctcc ctgtgcgatt tcgcgcacaa catggtagcg
     9901 gccgtcgatc agctggccct ggggtgatgc atcttcgctc atgtcttatc gtcaaatcct
     9961 tgatatgaga agagtccgta cgtcaattct gacagacatt ctagcttttg gcgatgtccg
    10021 ggacgaagcg cgcgcacgtt tcgagaagag ccgtctcgtg gctttgctcc agtttgcact
    10081 cgcgaatggc ctgtaccgac tcatcccata gatccccgat gcgttggcgg gaacgttcga
    10141 tggcaccggt ggactggaac agaccgatgg cgcggctcac atccgattcg ctgcgcgacg
    10201 aggcctcgaa catggcgatc agctcgtccc gcgccgcgca gtcggcatgc gcaatggcat
    10261 cggccagcag cacggtgcgc ttgccttcac gaatatcgcc gcccaccggc ttgccggtgg
    10321 cacggcttga accaatcaca tcgataagat cgtcttcaag ctggaacgca aggccgagcg
    10381 gtttgccgat ggccagcgcg cgctcgcgag cctgcccggg ggcggcgccg ctgcccaaca
    10441 gcgccagctc gatgggtgcg atggtggtgt agctggcggt tttccagcgg aacacattca
    10501 gcgaggcgtt cgccagcgct tcggcgtcct gcaatggtgc ctgttccacg gccagatcga
    10561 gaatctgacc gatttcgact tcgcgctgca tattcagaaa cgccgacgtc aatgcagtgg
    10621 catgggggag cagggcagcg gcctcgttga cgatgtcgat gcacaccgtg gccaacagat
    10681 cgccgagcat aagcccaagt ccacggccga tggcagggct tcccgtatcg gtctccaacg
    10741 cgcggtgagc actcggcttg ccacggcgca ggtcggaatc gtcgatgatg tcgtcatgca
    10801 ccagggcggc ggtctggaac acctcaagcg cgcaggcgac gtcgagcatg gcgttgcgcg
    10861 tatcggcatg gccgtcgaac gcatcgtagg cggcgagcat cagcagcgcg cgcagtcttt
    10921 tgccaccttc gctgctggat atcgcctgcc gtgagacagc atccacgaca tggcggcagg
    10981 cctcgggcat ctcggcttcc atgggcatgg cggaccatct gtccaccagg gagacgatgc
    11041 gggattcgat gttcgaacga tcggcgtcag ttttgcacat gccatctacg gtatcctcat
    11101 cgcactacga atggcatcct tcaccgtatt tcccgtattt ccaatggctc atggcgtgtc
    11161 gaccacagcc tcctgtccgg cgtgcgctcc atgcacgggc gggccatact gtatgcacgc
    11221 cgctatggaa gacggcggcg gcaacggcat cgaggaggat gacatgacaa cgaaccgtat
    11281 ggaatcggca gctggacaaa cgaatgatcg cgcagacggg cacggtgatg cggatagtgc
    11341 aggacgtgtg ctcgaggagc gcatcgtgga aaatcgttgc cggcatggcg aaggcgaggg
    11401 cagcgtgcca tcggcggaca gggctgcctg cgaggaattc ttcgacgcct tggaacccgt
    11461 ctgcgagcat gcggccgatg agatgcgtaa gcgattgcag caggggcgtc gccagtatgg
    11521 gccgagccgt gcggacggcg attggatgag ggaaccgctg caggtatggc tgtgcagact
    11581 cgaccagggc atgatcgacc ttgacgaggt gatgcttccg ttggcggtcg gcatcaacga
    11641 ggttcttgcg atgcgtgatg cgttgattct ttcggttgtc ggcgactcca ccatgcgtga
    11701 cccgcagatg ctgatggata ttgtccgaac gccccatgcc gggcatgtgg tgatggccgt
    11761 gcataaggcg ttgtccgccg agttcgacga tcgcgacggc cccgaccgcg accgatgccg
    11821 caccgcggtg cttatgctcg ccgccatggc caaggtgatg cccgagccca tgaaggttca
    11881 gccactggcg atcatctcat atatattgtg gtggaccggg gatagcagag cggaggatta
    11941 tgcgctcagc tgccttgcca tagatgagga atgctcgctt gccgcgattg ttctgaagtc
    12001 ggtgagcaat gggctgtacc cggcttgctg tggtggatga tgggattacg cagctgcgga
    12061 ttcgtctgaa atcgcgggtt cttgcgcgtg ttcgggaata atcgtcccta tcaggtggtt
    12121 tactcacata gttgacgatt tgcccttgcc agaagtgtgt ctatatggta tacgaggcgg
    12181 ggcgggtatt ccgcgaggag ggatagtttg gctaccaaga gcacaacggc cgctgagaac
    12241 accgaacagg tacaggacga ggccaaggtc gtttccgcca aaaaagccag tgccacgcgc
    12301 aagactgccg cggctaagaa gaccgcggct aagaagaccg ccaagtctgg cgaaggaacg
    12361 ggcagtgtca agaagaagtc cgctgccacc aagagcacga agaactccaa gaccaagaag
    12421 aggtccgagg aggatcttga cgaagtcgac gagttcgatg aggacgccga tctggacgac
    12481 gccaaggacg aggaccttga cgtcgatgat gtggacgatc tcgacggcat caacggcgag
    12541 tcggacgatg acgatgacga ctacgacgac gatgatgacg acgacgatga ggaggaggac
    12601 gataagtccg atgccccgga catcagcaag cagaagggcg cgttcgtcgt cagcgatgac
    12661 gatgacgatg acgaggacgt gaagcctcgc cgtcgccgcg gcaagatcgg caacccgaag
    12721 cgccgcgtcg tcaccgccgg tgccaccgcc gacccggtga aggattatct caagcagatc
    12781 ggccgtgtca gcctgctgaa cgccgaacag gaagtcgacc tatccgagcg catcgaggcc
    12841 ggcctgtacg cccagcatct gctggatacc gaaggcgaca cgatggactt caagcgtaag
    12901 cgcgagctca agtgggcggc caacgatggc aagaaggcca aggaccacct gctggaggcc
    12961 aatcttcgac tggtggtgtc gctggccaag cgctacaccg gccgtggcat gctgttcctc
    13021 gatctgatcc aggaaggcaa cctgggcctg attcgcgccg tcgagaagtt cgactggaag
    13081 aagggcttca agttctccac ctatgccaca tggtggatcc gtcaggccat cacccgagcc
    13141 atggccgatc aggctcgcac cattcgtgtg cctgtgcaca tggtcgaggt catcaacaag
    13201 ctgtcgcgtg tgcagcgtca gatgctgcag gatcttggcc gcgaacccac gcctgatgag
    13261 ctggcgcgtg agctggatat gccggtcgag aaggtgcagg aggtgcagaa gtacggtcgt
    13321 gagccgattt cgctgcacac cccgcttggc gaggacggcg attccgaatt cggcgatctg
    13381 atcgaagaca ccgacgccat cgcgccgtcc gacgccgtgg ccttctcgct gctgcaggat
    13441 cagttcaagc aggtgcttga gacgctgtct ccccgcgagt ccggtgtgat caagatgcgt
    13501 tacggtctgg aggacggcca gccgaagacg ctggacgata tcggtcgcgt gtacggtgtg
    13561 acccgtgaac gtatccgtca gatcgagtcg aagaccatgt cgaagctgcg ccacccgtct
    13621 cgttcgcaga cgctgcgcga cttcctcgat cagtgacgat gccgcttccc cgaggcttca
    13681 gccttgggga agctttttgt cgtggtatgg attgacaact agtggaagag gcacatggct
    13741 aaagaggatt acggcgcaaa ggatcttacc gttctcgaag ggcttgacgc ggtacgcaag
    13801 cgtccgggca tgtacatcgg taccacggat tcccaggggc ttatgcattg cctgtgggag
    13861 atcatcgaca atgccgtgga tgaggcgttg gcaggattct gcaatgccat cgtcgtcaca
    13921 ttgcatacgg acggctccat caccgtggcc gacaacggtc gaggcatccc cgtcgacaag
    13981 gaaccgaaga cgaagctttc cggtgtcgag gtcgtactga ccaagctgca tgccggtgca
    14041 aaattcggca attcctcata taatgcggtc ggtggtctgc atggcgtcgg ttcgtcggtg
    14101 gtcaatgctt tgagctcccg actcgacata gaggtcgacc gtgatggcaa aacctatcat
    14161 atggcgttcc atcaggggca tcccggcgtc tataccgata ccgacccgga acacccttcg
    14221 ccggatgccc cgttcaagcg tacacgcaag aacaagccca ccgagctgga tattatcggc
    14281 aaggtgccgc cgaagagaac cggcacacgc atccggtact gggcggatcc tgaaattttc
    14341 aacaaaaccg ccgaattttc gtatgagcag cttgtcgacc gtgtccgcca gaccagtttt
    14401 ctggtgccgg ggctgaagat caccgttatc gatgagaata ttgcgcagga gccggctccc
    14461 ggcgaaccgg atcatgagat gacttcggtg ccggaaggag tcggcgccgg cgagaccgtg
    14521 acggccgatg ccgcttcggc cgtcggcgaa tccgattccg cgcagactca gggcgatgag
    14581 gatcttgcct tgaacgaggc tgaaaccatt gcggacggcg cgttcggcac acaggtcgat
    14641 cacccgcgtg tggccgagtt cctccacaat ggcggtgtca aggatttcgt cgattatctg
    14701 tccaaaggcg agcctgtcag cgacatctgg cgtattcagg gtgaaggcac atacgaggag
    14761 gagacccagg cggtcggcgc gaacggcgaa ctgcatgcgg agaagatcac gcgtacctgc
    14821 ggtgtggata tcgcactgcg atgggtgaat ggctacgaca cagtgatgcg cagcttcgtc
    14881 aacatcatcg agactccggg cggcggcacg catgtggacg gtctgatgaa ctccgtcacc
    14941 aggcagatcc gcaaggcggt cgaagcgaac gcacgcaagc tcaaggtgaa tctcaaggat
    15001 tccaatatga aggttgagcg cgacgacatc atggccggtc tggtggccgt ggtcaccgtg
    15061 cgtattgcgg aaccgcagtt ccaggggcag acgaaggatg tgctcggcac cgcgcaggtc
    15121 aagccgatcg tcacgcgcat gagcgataag cagttcggcg agatgatcac cggatccaag
    15181 cgcgggtata aggagcaatc caaccgtgtg ctggagaaga tcgtcggcga aatgcatgcc
    15241 cgcgtgcagt cccgtaaggc caaagaggtc acacgtcgca agaacgcatt ggaatcggcg
    15301 tccatgccgg ccaagctttc cgactgccag ccgggcaatg atgatgtggc cgaactgttc
    15361 atcgtggagg gcgattccgc gcttggcacc gccaaagccg cccgcaatgc gggattccag
    15421 gcgcttttgc cgattcgagg caagattctg aatgtgcaga aggcctcgat cacgcagatg
    15481 ctgtcgaata aggaatgcgc ggccatcatt caggtggtgg gcgccggttc ggggcaaagc
    15541 ttcgatatcg aacagtcgcg ctaccacaag gtcatcatga tgaccgatgc cgatgtggat
    15601 ggcgcccata tccgtattct gctgcttacg ctgttctatc ggtacatgcg accgctgatc
    15661 gagaacgggt atgtgtatgc cgcagtgccg ccgttgcatc gcatcgcgtt gaccggttcg
    15721 cataagggcg agttcatcta cacgtattcc gatgatgagc ttgccggcaa gctggccgaa
    15781 ctcgatcgca aacatatcgg gtataacgac gatatccagc ggtacaaggg cctgggcgag
    15841 atggacgccg accagttggc ggataccacc atggatccgc gcacgcgcat gctccgtcgt
    15901 attcgcatgg aggatgccga gcaggccagc gagatcttca gtctgctcat gggcgacgat
    15961 gttccgccgc gcaaggcgtt catcgtggaa aacgccgacg acttcgaccg ttccaagatc
    16021 gatacctgat ccggttgcag aatcgggcgg ccggtcgccg gtgcatgaat cgacttgtgc
    16081 gcgggaacgg ctgcgatgga ggctccggtg tcggcttggc cgtatccgga gccttcgttg
    16141 caataaggct gtgcgaagtc ttattgattg tctgcgcggt taagccatag gtcgagcttg
    16201 tattggttaa gctcggtgtt cgggtcgtaa ttgtcctcaa gccggctgcg gtacatcgcc
    16261 accagttcgt cgccgcgtcc caacgcttcc agagccgctt cacgcagcgt ctcccattcg
    16321 taggggacga cctcttcggg gaacatcacc atgctttggt tcgcgttggc ctgctccacc
    16381 cgattggtga agtcgatgag atcctcccag cgttcggagg cgataaggcg tgcggcatag
    16441 gtgtcggcga gcggttcgat ggtattgtgc tcgcgcagga aggcgtcggc ggcttccgca
    16501 tctccgctga tgcgcatcag atcgtgacgg aggaattgta cggcatggtc gaattggtgg
    16561 catgcggttg cggccagctc ccgttccgtg agcaatgagg ggtcgagcga aacgagattg
    16621 tcgagatccg cggcgctgag cttgatatcg tcggctgcgt cgacagtgcc ggtctgcccg
    16681 cttgtctgtg tggatcggct tgagaattcg gccattgacg ctaccgcctt gttcaacgca
    16741 tcataggcga acatgcgagt gtcgtcccat tgggcgaacg ataggctgca agacagcaat
    16801 tccaccattt gcatggcgtt gaggcgaaaa tcatcgttgc aggcgaccgt ggtgatcatg
    16861 cgcagcgcct gttcgccggt catcgggtcg gcgttgcagg ccacggcgtc catgtagacc
    16921 cgtacgttct ggatcagatc cttaaggtag tcgaatcctt cgttgtctcg atccgccacg
    16981 ttgcctacga atttcgccgt catttccaag gccttggcga ggttgcccac ggcgtcgacc
    17041 cagcgtgtgc tgaccagcgc gttgccgacc acggcgtcga cgccggaaag cgcctgcgag
    17101 tcaagatgga aggtcggcat gtcggcgcgt ggcatttcca cgccggtttc ggtccgttcc
    17161 gctgtgggaa cgatggcggc gatggagtcg aaataccatt gcatgggcat gccgatgacg
    17221 ttgtccgcgt cggatagggg agcgacgggc gcgtcgttgc ggttctcggc atcgtgctcc
    17281 gaagcctcgc ggatcagatg attccataga atcgtcggac cgtcgaattc tcctgttctc
    17341 agccagccgt tgttgacgta gtcgctgagc tcctcggcgt catgccgggc gtcgatgcgt
    17401 tcatgagata tgctgcccat agccaccttt cctgcactgg taaggctaca acctgcgctg
    17461 gtcgaagggg accggcgaga ggggagccat gcgaaaggat gaggttcgct gagagcaaat
    17521 catcctcaaa acgacaaaac aagtcaaaat gtcgaataat ataaagtttg tagtcatgtg
    17581 gttcgcagtg atcgcaagac tggaaaggag ccggtggaga catggataat tcaaagttct
    17641 ctcatctcct ttggctgaat acctagttga agccggtttc tttccgtttc ttttccctca
    17701 tttccctggg gtcttatggc tccggggaat ttgctttttg caggtgcggc gccatgctgc
    17761 ccgcaccctg tgaggcaacg attgtccttt cgaataagtg ccttcgacaa tatgcgcgtt
    17821 gctcgcatat actggggtgt tggctgagag agcgacagat tggaacatag tgttgcaaga
    17881 taacggcaac gttgataaaa gcgaaggcga gggaagagcc gcaaaaggca cggcgcttaa
    17941 acacgcggca acggcacggc gaagaatccc ggaagcggcc agacgtgcat gcggcagcgc
    18001 aggcggcctc atcgtgcgtg gcacgcgcac tgcaggcagt gcaatcgcaa agtgctggcg
    18061 aaccgtggta agcgccctga atcccaacgc ctcatcgaac ctggatgcga aacaagtgtt
    18121 ccgtatccgc agaaccgtcg tgttctcagg catagcagcc gttgtactga tcgtggctgt
    18181 tatcgtggct gtatcagtgc acgcgaatcg cagtgcacag gcagacaaag ccggcacggt
    18241 ggtgaacgcc caaaccagta agaccaagca atcgccatct gcaaaagcga cgaagaaaac
    18301 cacggcgggg aaaaccgcgg cagagaacag ttcggcgaag aaaactcagg aacagtccga
    18361 cacatcaagc tcctcaacgg atgagacaaa gcggcaggtc gaagcgctcg ccgcttcgat
    18421 cagcgatgaa gagtccgcga cgatcaaggc caaagcggac gaaacggcgc acaacagcgg
    18481 caaacccgtt acgcaataca cctactgcat tgccggcaaa ggcaatgtgg gcgctttgga
    18541 cggtttcgcc aacaccgtgt accgcgtgct caacgatccg cgcggctggc cgcgtgccgg
    18601 agccaccttc gtcaaaggcg acggcgacgc gtgcaacttc accgtggtgc tttccgaagc
    18661 gaaatacatg cagacgttcg actccggatg cagtgccgaa tacagctgcc gtgtggggga
    18721 taacgtcatc atcaacctcg accggtggaa cggcggcatc ggcaactgga tggaagccgg
    18781 cggcaatctc gcacgctacc gcaccatggt gatcaaccac gaggtcggcc atgccctagg
    18841 gcatatcgat aatgagacca cctgtgccgg tgcaggcaag cccgcgccgc tgatgcagga
    18901 acagtccatg catctggacg gctgcacggt gaacgagtgg ccgctcgatg acgaactgtg
    18961 gagaagctga gggggaggcg ccctgcacag ctgggactat tcgatccggc ctgtcaggta
    19021 cttgtagaac tcagggtcca gcggcttatg cagacgtaag gtcgagagca ccacattgac
    19081 ggtatcgtcg ccactggccc cgggcttctg cactgcgcgc atgttcgaga tcgaagcgac
    19141 atggccgaga taatagtatt tcttatcggt ctcctcctgc ttgcgcataa cgaacagcgg
    19201 cacgaaatgc gtctcatccc aatacgtggt gtcggcatcc ttttgcaacc atttgaattc
    19261 cggggaattc aagagacgat tgttcttgct ataccagtcc atctcctgcg tgttgaggaa
    19321 ccggtcctcg tactggcttg cctcgtattt gacaagaatg ggcatggtgc cggttgccgt
    19381 atggcataag tatccgccga cgttctggcc gttgacttcc ttcatccatc cgcacagccg
    19441 ttcgatgtcg gtcagcgtgt accgatgccc atatacaaag ccatgctcga catccagccg
    19501 ctgatccttc acatcgcgga acaggtcccg gcagttgagc agtccggttc gcagcgtatc
    19561 ggcgaaaaac agacggaacg tgctgttgcc ctgcagcaga cctacgaacg gctcgcttaa
    19621 tgaaatatcg ccgttggcgc ttcgggcaat caacggaacg tcgccgaatc gcttcatgtt
    19681 ctgctgagtg aaataggagt agtccaatac cttcagcgcg gattcccatt gcgcgtcgga
    19741 atcgtcggct gcggcgaaat cgtcgcggat cgcctgtctg agcgcagaag ccggcatggc
    19801 cgacactggt ttccaaggaa gcgtgtctcc caagcgctcg ttgccaaagc ggcagagtct
    19861 atccaaaatc accagctcat gcggacggac gccggggagc agcagttccg tggccatctt
    19921 cagtatcccg tcttcgacag gggacgtcgg ttcaagcata ttggcgaagg attgcgaatc
    19981 ggcgttccgt ttgccagcca gactgcgctc gcaggcccgc acgaattcca gatacgaggc
    20041 ggtgaggatg ctgccgcctt tgcctttctg ccctttgccg ctgctgcggc gcaatgcgag
    20101 catgccgggc agcgaggggt catgggcata tacatcggta agcatgggta tgcgcccgat
    20161 ctggaaacga atctgccggt attcttcgga aagccgtttc atattggacc agtcggctgt
    20221 gtcgagggcc ttgagaatac gttcccgtga gatacggtcg aagctgatgg aacttaaccc
    20281 gatactgtta cgggacgcga tgttcttatg aggattgccc tttctgccat acagcgcgac
    20341 gggaataagg aagttattgg cgtagttgcc gatgaaatcg atgacagtga cgctgtcctt
    20401 ataggcgaac ttgcgcaggc ctcgaccaag ctgttgggtg aacacgatgc tggacttggt
    20461 gttgcgtagc atgacgatct ggttgatcgc cggaacgtcc acgccttcat tgaacaggtc
    20521 gacggtgaag atgtagtcga gtctgttctc ctcaagatcc ttgacggcct gcttacgttc
    20581 ctcgtccgaa ttcttgccgg taatggcgcg ggtccggtaa tggcgctcct tgtactcgta
    20641 gtagcgttcg ttgaacaatg ccgacagccg ttcggcctca tcctgccggc tgcagaacac
    20701 cagtccggtc agatcctgac ggtaaggcgt gtacttgcga agctgatcga tgatgtagtc
    20761 gactcgtttg gcattggtaa gctggccgat ctcataggtc agctgatctc tgttcccgga
    20821 attcaggcca ttgtccaaca gaatgccttc ggaagcctgg ccgttatccg ccgcccccag
    20881 atattcggcg atgccatagt agtggaacgg gcagagcata tcctcgtcca acgcctgctg
    20941 gagcctgatc tcataggcga cgttataacc gaacatctcg aagatgttca cgccatcggt
    21001 acgttccggt gtcgcggtca tgccaagcat gaaatccggt gtgaaatagt cgatgatccg
    21061 acggtagctt gcggcggaaa
//
