LOCUS       NZ_CP009478            13119 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Burkholderia pseudomallei MSHR2543 chromosome I, complete sequence.
ACCESSION   NZ_CP009478
VERSION     NZ_CP009478.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei MSHR2543
  ORGANISM  Burkholderia pseudomallei MSHR2543
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 4240604)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.E.,
            Davenport,K.W., Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C.,
            Coyne,S.R., Broomall,S.M., Li,P.E., Teshima,H., Gibbons,H.S.,
            Palacios,G.F., Rosenzweig,C.N., Redden,C.L., Xu,Y., Minogue,T.D. and
            Chain,P.S.
  TITLE     Complete genome sequences for 59 burkholderia isolates, both
            pathogenic and near neighbor
  JOURNAL   Genome Announc 3 (2), e00159-15 (2015)
   PUBMED   25931592
  REMARK    Erratum:[Genome Announc. 2016 Apr 21;4(2):e00313-16. doi:
            10.1128/genomeA.00313-16. PMID: 27103731] Publication Status:
            Online-Only
REFERENCE   2  (bases 1 to 4240604)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.,
            Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C., Coyne,S.R.,
            Broomall,S.M., Li,P.-E., Teshima,H., Gibbons,H.S., Palacios,G.F.,
            Rosenzweig,C.N., McMurry,K., Redden,C.L., Xu,Y., Currie,B., Mayo,M.,
            Minogue,T.D. and Chain,P.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-SEP-2014
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; Allpaths v.
            44837; Phrap v. SPS - 4.24; HGAP v. 2.2.0
            Genome Coverage                   :: 463x
            Sequencing Technology             :: Illumina; PacBio, 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000959225.1-RS_2024_06_16
            Annotation Date                   :: 06/16/2024 14:42:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,715
            CDSs (total)                      :: 6,638
            Genes (coding)                    :: 6,472
            CDSs (with protein)               :: 6,472
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 166
            CDSs (without protein)            :: 166
            Pseudo Genes (ambiguous residues) :: 0 of 166
            Pseudo Genes (frameshifted)       :: 85 of 166
            Pseudo Genes (incomplete)         :: 110 of 166
            Pseudo Genes (internal stop)      :: 20 of 166
            Pseudo Genes (multiple problems)  :: 39 of 166
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:58:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3313010
            Orig. end                         :: 3326129
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009478.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The DNA was obtained from USAMRIID.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..13119
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="9"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..13119
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13119
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:8119](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8119
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            925..5004
                     /locus_tag="BG16_RS28220"
                     /old_locus_tag="BG16_2977"
     CDS             925..5004
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004543806.1"
                     /locus_tag="BG16_RS28220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_2977"
                     /product="TOMM system kinase/cyclase fusion protein"
                     /protein_id="WP_011204838.1"
                     /sec_met_domain="Pkinase (E-value: 3.3e-47, bitscore:
                     158.9, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASVLAERARAGNRRAPRALAPPLPGDGDELQGEHRYRLGAVLG
                     EGGAGRVHEAIRLDTSARVAIKLLREDAPRGARERARLRARFRRETALCARLSHPHIVA
                     LLDSGETPDGLLFAVFEHVAGRTLRALLAADGALAAETTGALMAQVLDGLAHAHANGVV
                     HRDLKPQNVMVTTRDGEPCAKILDFGIGALLPDAHAADELTLTATTEVLGSPQYCAPEQ
                     LRGEPPTAKSDFYAWGLIVIECLTGHPVMQGASLADVLYQHLSPVDVALPPAIAAHPLG
                     DVLRDALNKDPRQRAESAQALANRFRAIHFPALVGGLRYGARHGRRAQAEPGVAAREPG
                     GTIALDAPVGRRQVTALCCRVSVVSTLARPADAAADDEALDAFHAHWLTRCSDIAVRYG
                     GHVAGALGDTLLFYFGYPEGIDRPAQRACRAALEMTRHAGQPAGAPRSSDGDARACAPA
                     WRIDIAGAIHVGTAFATARGASGGVLASAALGLQRIAQPGGILLSDEAARALERHVDAA
                     PTALTFAAPGAAPQPVRELLGERYERGPFESLELGDATPIVGRDREQAALARAWRDAVR
                     AAAGGRRARRRATLVVGEPGIGKSRLVHALRELVRAQRGACAACVCLPEQTNHALFPIL
                     RFVRAHWQLDVGDPHALDRMLEAFDGDRASARATLAAWLGLPGGADTLRWSGARQQQAL
                     FDVLCQLLGSLGGGGPVLLIVDDVQWCDSATDDFLDALAHHPACAAVCVVLTSRPERLE
                     RWRRGAERLMLRRLSAAATRNLIVSLMPGAGTQRAALDFLVKRTGGVPLYVEETVRALA
                     EGGVAPGAGARLPDLAQAGRCPLPGSLRETLELALERADDALDTVQLAATIGLEVDARL
                     LAEASPHAGAELDERLRRLIEGRVLYAQHRIGGATYVFRHALLREAAYESMPAATRREY
                     HRRVAQALLACVAQGDPAARSASIADHFARAHAFAAAVPHGIEAARRALARALHDDAIR
                     YAGAVRGWLLHCDYPGQHEDAVSVDLTLAHAQMARDGWGDPRVREHTDRVLSRVGELSD
                     AKAAAGALWTIAVYHHVAGDRDAVRRIGGQLSALARASARADLGVAADTLHGMALWIDG
                     HYTLALDAFDAALAAYDPRRDGDHRHVFGLDTRAWAQSARACVLWGIDDDVARTLALAR
                     DAVQLATCTDHLPTIGLTMMYLARMQQCVGDREGARATADAVLRLSRCHGLNAVERYAA
                     VVRAWCDGDRDAARANVDALRASGCMLGLTYYASVAADIDAERGDARAALATLDECLAL
                     AESMDERHYVAELLLKKARCVRDAHGRRAADDAQALCARAAAVARRSGMARIERKAQAE
                     LRELQRELRSTTGEER"
     gene            5001..5363
                     /locus_tag="BG16_RS28225"
                     /old_locus_tag="BG16_2978"
     CDS             5001..5363
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03795"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004196290.1"
                     /locus_tag="BG16_RS28225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_2978"
                     /product="BMA_0021/BMA_0022 family TOMM bacteriocin"
                     /protein_id="WP_004196290.1"
                     /sec_met_domain="TIGR03795 (E-value: 1.6e-45, bitscore:
                     151.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRSPNVPTYDQFLEYRAVIVQAIAAAWHDAEFREELIAHPVDA
                     LHKRFDYRFPMKMHLKVHENSATWTPLTNGGWTTNEVNGLDLVLPPAPPPEQRAAALAA
                     YNARHISLFGPDRKEI"
     gene            5365..5727
                     /locus_tag="BG16_RS28230"
                     /old_locus_tag="BG16_2979"
     CDS             5365..5727
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03795"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004541074.1"
                     /locus_tag="BG16_RS28230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_2979"
                     /product="BMA_0021/BMA_0022 family TOMM bacteriocin"
                     /protein_id="WP_004189426.1"
                     /sec_met_domain="TIGR03795 (E-value: 2.7e-48, bitscore:
                     160.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAENNAVPTHQSLLDFPEVYLRAIALSWENEQFKRELLADPLDAL
                     ERYFDYRCPWILNLKVAEVPPDESHYGWDAKRQRWNLPVNTLRVGIPTPPKHLAEEGIA
                     LAAYNDAGPAYLFTCC"
     gene            5819..8119
                     /locus_tag="BG16_RS28235"
                     /old_locus_tag="BG16_2980"
     CDS             5819..8119
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03604"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188975.1"
                     /locus_tag="BG16_RS28235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_2980"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_004543962.1"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 1.3e-09,
                     bitscore: 35.9, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 5.8e-18, bitscore:
                     62.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.2e-90, bitscore: 302.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 4.1e-74, bitscore:
                     247.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDDFSRVLRFKPHLLVRDAGSGALYVVDEFRRSVLPGDVFPAIA
                     ACMRDRLTIAQTFAALAARFSQWEVLAALDQLVRRGYVRADAPGERDAELAFHERAGVD
                     GDAASGVASRLTVAVEAFGVDPRAQLDAFAACGIGVAPDAPLTVALTDGYDRAELIVAA
                     ERAAARGGALLVVVADRVEPLIGPLLGAAAGLAASAGSTAPTAPSTSPAPQDAADAPPC
                     IECVRYWTALNHPVETLLARLHGGDAARLPPARSRASAAAVAAVVASFVEQIAVNAQRR
                     RHAGSHIVSLRVDTLATAAHRVVRRPQCPRCAHAGWMREQAERPVTLASADAGARRDGG
                     YRTLAAAELFKRYGHLISPVSGPIAYLHPMPGRNAGMRHVYVAGYLVCPPGAPRENRFD
                     KLCSGKGASDAQARASALAEALERFSGVYQGDEAALRGSLAQLSAHAPPGSGPIDVNAL
                     QQYSDRQFERRERHNATTDDPRKQVPRRFTRDSVIDWTPAWSIATGARRLVPLAYCYAE
                     TPASSGADYCVHNPNGCAAGACIEEAILQGLLELVERDAVAIWWYNMLRRPAVDIESFG
                     DPYFDALAADYASLGWRLWALDITHDLRIPVFVALARETATGRFSIGFGCHPDSRIALQ
                     RALTEVNQLLDVGAAAPPPWDVDKLPDDAFLHPDPALPPVRAPARAPHGRCDLKRDIED
                     CVARLAAAGIDTLVVDKTRPDIGLPVVQVIAPGLCHFWPRFGAPRLYSVPVAQRWRERP
                     RDEDALNRALLFL"
     aSDomain        5831..6070
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BG16_RS28235_Cyanobactin_D_RRE.1"
                     /evalue="9.00E-12"
                     /identifier="RREFam007.1"
                     /label="BG16_RS28235"
                     /locus_tag="BG16_RS28235"
                     /protein_end="84"
                     /protein_start="4"
                     /score="35.9"
                     /tool="antismash"
                     /translation="FSRVLRFKPHLLVRDAGSGALYVVDEFRRSVLPGDVFPAIAACMR
                     DRLTIAQTFAALAARFSQWEVLAALDQLVRRGYVR"
     aSDomain        5831..6112
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BG16_RS28235_NHLP_CD_RRE.1"
                     /evalue="4.10E-20"
                     /identifier="RREFam015.1"
                     /label="BG16_RS28235"
                     /locus_tag="BG16_RS28235"
                     /protein_end="98"
                     /protein_start="4"
                     /score="62.6"
                     /tool="antismash"
                     /translation="FSRVLRFKPHLLVRDAGSGALYVVDEFRRSVLPGDVFPAIAACMR
                     DRLTIAQTFAALAARFSQWEVLAALDQLVRRGYVRADAPGERDAELAFH"
     gene            8189..8965
                     /locus_tag="BG16_RS28240"
                     /old_locus_tag="BG16_2981"
     CDS             8189..8965
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009963399.1"
                     /locus_tag="BG16_RS28240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_2981"
                     /product="class II aldolase/adducin family protein"
                     /protein_id="WP_004522828.1"
                     /transl_table=11
                     /translation="MTNRTPNQPFARPARFAQAEWQARVQLAAAYRIFDHLGWSELIYN
                     HISLRVPGEDTHFLINPFGLHYREVCASNLVKVDVDGHSVGHADWPFNPAGVTFHAAIH
                     AALPDAHCVMHVHTTPTMAVCATRRGLSFSNFYAAQLHGRVAYHDFEGITVRPDEGRRI
                     VDSAAGRPVLLLRNHGPVAIGRTLAHAFSLMWLLHRACEVQVATHALGEPLEIDAPILD
                     ACARDSLNLDPRHGAGQDAFDALQRIVDRIDPGYRS"
     misc_feature    complement(8982..8995)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.4"
                     /tool="antismash"
     misc_feature    complement(9013..9026)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.46"
                     /tool="antismash"
     misc_feature    complement(9013..9027)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    complement(9014..9023)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     misc_feature    complement(9017..9031)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.55"
                     /tool="antismash"
     misc_feature    complement(9017..9032)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.68"
                     /tool="antismash"
     misc_feature    9018..9031
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.07"
                     /tool="antismash"
     misc_feature    complement(9072..9085)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.8"
                     /tool="antismash"
     misc_feature    complement(9073..9086)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.03"
                     /tool="antismash"
     misc_feature    9074..9083
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     misc_feature    complement(9093..9104)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    9132..9146
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.7"
                     /tool="antismash"
     misc_feature    complement(9323..9337)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.29"
                     /tool="antismash"
     misc_feature    9340..9355
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.17"
                     /tool="antismash"
     gene            9448..11811
                     /locus_tag="BG16_RS28245"
                     /old_locus_tag="BG16_2982"
     CDS             9448..11811
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004534205.1"
                     /locus_tag="BG16_RS28245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_2982"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_045588268.1"
                     /transl_table=11
                     /translation="MRSAVAVALAVALLGAALLSVERFGAARSRASAAIPASIGARLSG
                     CAFIAVRIGAALSRRAPSPAHAAAPGVARPDFDAIERVFGPIRMRERRAHGATCTADAP
                     DASHAGWIEPARACSAAAHAAPGRGAEGAPNTMPRPSEAGAAAVPQSQPYLDMIDSTFR
                     EPAAIVLALSLLGMIALALLPVFRIRRLALRLGEAQGALEMSEARARAALVAVGDGVIF
                     TGRAGRVECLNPAAERLIGMLADDCRGRPLVSTLRLSRTATSASSGAFAASAGLDAPDS
                     PSSAASPDAPLGDLEDGGSCDATLYRADGGAIAVRATASSIAPPPGHARRACGSGRVLV
                     LKSLATEHELVRRLAWQTTHDPLTGLASRAEFERHVGFALAADVREPVALLFVDLDRFR
                     IVNDTCGYAAGDAMLAALAARLVSCAASADVVARLGGDEFCVLLDARDEASAVSAAERL
                     RASVDGFVFVWDGQPFSVTASVGVALLGGPGRAPRVEDAVRLAGIACDVAKARGRNRVQ
                     LADPHDHELAHHISDVSWCARVRQALEYDDFRLYVQPIVDTATQSATGLPRARRGELLL
                     RMGALGEREGVAPPGLFIRAAERYGLVTDIDRWVVRTVLDALARTRSRRFSEYAINLSG
                     ISIGDERFLDYVLEQFARTRVAPALICFEITETAAIANLAGALRFMHELKALGCRFALD
                     DFGSGMASLSYLKQLPVEYLKIDGSFVTGIANDAASLDIVASINDIGHAMNCKTIAEYV
                     DSAATLQKLAALGVDYAQGYYIGRPVPWCEAARA"
     misc_feature    complement(12489..12503)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.19"
                     /tool="antismash"
ORIGIN
        1 tcgccgatcc gtacgtgtcg cgcatccacg cgagcatctg ctggacggcg gggcggtggg
       61 agctgcacga tcacggccgc aacggcacgt tcgtgtccgg gcgattcgtc ggcgaaggcg
      121 aatgcgtggt gctgcgcgac ggcgatctga tccagttcgg cagcgccggc tcggttcgct
      181 ggcgcgcgcg cgaactgggc gagcccgtcg acatgctctg gccgctgcgc gcgcccgcgc
      241 ggccgatcgc gctcgatcgc acgcacgcgc tgccgggcgc cgcgttcacc gtcagccgct
      301 ccgcgcaggg cgactggctc tgcaacgaca cgacgcccgc gcgcgtgctg catgacggcg
      361 acgcggtgat ctgcggcgaa ttcgcgtggc agctggtgct cgcgcatcgc ggcgtgacgg
      421 ccgcgctgcc gcgcgcgacg caggtcgcga cgctgccgca gcgcatcgat ttcacggtga
      481 gccgcgacga ggagcacgtg acggcgacgc tgcacacgcg cggcggcgcg gtcgatctcg
      541 gcgcgcgcgc gcatcactac tgcctcgtga cgctcgcgcg cgcgcgcttc gccgatgcgc
      601 aggcgggcta cgacacggcg tcgcgcggct ggatcgagct cgacgtgctc gcgcggatgc
      661 tcggcctcga cgaatcgcac atcaatgtgc agatccaccg cgcccgcacg cagttcctgc
      721 cgctgctgtc gcccggctcc gccgaactcg tcgagcgccg ccgcggcggg gtgcgcttcg
      781 gcgcgctcgc atttcgcgtc gtgcgcggcg atcggctcga atgccagtcg gccgacgccg
      841 acgcttcagc gccgctgccc gatccgctcg cgcgcggcgc ggcgacgttc gtctcgcccg
      901 ccgcgctcgg ctgagcggcg cttcatgtcc gcttccgttc tggccgaacg cgcgcgcgcc
      961 ggcaatcgcc gtgcgccgcg cgcgctcgcg ccgccgctgc ccggcgacgg cgacgaactg
     1021 caaggcgagc atcgctaccg gctcggcgcc gtgctcggcg aaggcggcgc gggccgcgtg
     1081 cacgaggcga tccggctcga cacgtcggcg cgcgtcgcga tcaagctgct gcgcgaggat
     1141 gcgccgcgcg gcgcgcgtga gcgcgcccgg ctgcgcgcgc gctttcgccg cgagacggcg
     1201 ctgtgcgcac ggctgtcgca tccgcacatc gtcgcgctgc tcgacagcgg cgagacgcca
     1261 gacggcctgc tgttcgcggt gttcgagcac gtcgccgggc gcacgctgcg cgcgctgctc
     1321 gcggccgacg gcgcgctggc cgccgagacg acgggcgcgc tgatggcgca ggtgctcgac
     1381 ggcctcgcgc acgcgcatgc gaacggcgtc gtgcatcgtg acctgaagcc gcagaacgtg
     1441 atggtgacga cgcgcgacgg cgagccgtgc gcgaagatcc tcgacttcgg aatcggcgcg
     1501 ctgctgcccg atgcgcatgc cgccgacgaa ctaacgctca ccgcgacgac cgaggtgctc
     1561 ggctcgccgc agtactgcgc gccggagcaa ttgcgcggcg agccgccgac cgcgaaaagc
     1621 gatttctacg cgtggggcct gatcgtcatc gaatgcctga ccggacatcc ggtgatgcag
     1681 ggcgcgagcc tcgcggacgt gctgtatcag catctgagcc ccgtcgacgt cgcgctgccg
     1741 cccgcgatcg ccgcgcatcc gctcggcgac gtgttgcgcg atgcgctgaa caaggatccg
     1801 cggcagcgcg cggaatccgc gcaggcgctc gccaaccggt tccgcgcgat ccacttcccg
     1861 gcgctcgtcg gcggcctgcg ctatggcgcg cgtcacgggc ggcgcgcgca ggcggagccg
     1921 ggcgtcgcgg cccgcgagcc gggtgggacg atcgcgctcg acgcgcccgt cgggcggcgg
     1981 caggtgacgg cgctctgttg ccgcgtgtcg gtcgtctcga cgctggcgcg gccggccgac
     2041 gcggcggccg acgacgaagc gctcgacgca tttcacgcgc actggctcac gcgctgctcg
     2101 gacatcgcgg tgcgctacgg cggccacgtc gcgggcgcgc tcggcgatac gctgctgttc
     2161 tacttcggct accccgaggg gatcgatcgc cccgcgcagc gcgcgtgccg cgcggcgctc
     2221 gagatgacgc ggcacgcggg gcagccggcg ggcgcgccgc gttcgtccga cggcgacgcg
     2281 cgtgcgtgcg cgcccgcgtg gcgaatcgac atcgcgggcg cgatccatgt cggcacggcg
     2341 ttcgcgaccg cgcgcggcgc gtcgggcggc gtgctcgcga gcgcggcgct cggcctgcag
     2401 cgcatcgcgc agccgggcgg cattctgttg agcgacgaag cggcgcgcgc gctcgagcgc
     2461 cacgtcgacg ccgcgccgac tgcgctcacg ttcgccgcgc ccggcgcggc gccgcagccg
     2521 gtgcgcgagc tgctcggcga gcgctacgag cgcgggccgt tcgaatcgct cgaactcggc
     2581 gacgcgacgc cgatcgtcgg gcgcgatcgc gagcaggcgg cgctcgcgcg cgcatggcgc
     2641 gatgcggtgc gcgcggcggc gggcgggcgt cgcgcgcggc ggcgcgcgac gctcgtcgtc
     2701 ggcgagccgg gcatcggcaa atcgcggctc gtgcatgcgc tgcgcgagct ggtgcgcgcg
     2761 cagcgcggcg cgtgcgcggc atgcgtgtgc ctgcccgagc agacgaatca cgcgcttttt
     2821 ccgatcctgc gtttcgtgcg cgcgcactgg cagctcgatg tgggcgatcc gcacgcgctc
     2881 gaccggatgc tcgaagcgtt cgacggcgat cgcgcatccg cgcgcgcgac gcttgccgcg
     2941 tggctcggcc tgccgggcgg cgcggatacg ctgcgctggt cgggcgcgcg gcagcagcag
     3001 gcgcttttcg acgtgctgtg ccaactgctc ggctcgctcg gcggcggcgg tcccgtgctg
     3061 ctgatcgtcg acgacgtgca atggtgcgac agcgcgacgg acgattttct cgacgcgctc
     3121 gcgcaccacc cggcgtgcgc ggcggtgtgc gtcgtgctga cgtcgcggcc ggagcggctc
     3181 gagcgctggc ggcgcggcgc cgaacgcctg atgctgcgcc gcctgtcggc tgccgcgacg
     3241 cgcaatctga tcgtgtcgct gatgcccggc gcgggcacgc agcgcgcggc gctcgatttt
     3301 ctcgtgaagc gcacgggcgg cgtgccgctg tacgtggagg aaacggtccg cgcgctcgcc
     3361 gaaggcggcg ttgcgccggg cgcgggcgct cggctgcccg atctcgcgca ggcggggcgc
     3421 tgcccgctgc cgggcagcct gcgcgagacg ctcgagctcg cgctcgaacg cgcggacgac
     3481 gcgctcgata ccgtgcagct cgccgcgacg atcggcctcg aggtggacgc gcggctgctc
     3541 gccgaagcgt cgccgcacgc gggcgcggaa ctggacgagc ggttgcggcg gctgatcgaa
     3601 ggccgcgtgc tgtacgcgca gcaccgcatc ggcggcgcga cgtacgtgtt ccgtcacgca
     3661 ttgctgcgcg aggccgcgta cgaatcgatg ccggccgcga cgcgccgcga atatcatcgg
     3721 cgcgtcgcgc aggcgctgct cgcgtgcgtc gcgcagggcg atccggcggc gcgctcggcg
     3781 agcatcgccg atcacttcgc gcgtgcgcac gcgttcgccg ccgcggtgcc gcacggcatc
     3841 gaagccgcgc gccgcgcgct cgcgcgcgcg ctgcacgacg acgcgatccg ctacgcgggc
     3901 gcggtgcgcg gctggctgct gcattgcgac tacccggggc agcacgagga tgcggtatcg
     3961 gtcgacctga cgctcgcgca cgcgcagatg gcgcgcgacg gctggggcga tccccgcgtg
     4021 cgcgagcata ccgaccgcgt gctgtcgcgc gtcggcgagc tgagcgacgc gaaggcggcc
     4081 gcgggcgcgt tgtggacgat cgcggtgtat caccacgtcg ccggcgatcg cgacgcggtg
     4141 cgccgcatcg gcgggcaact gtcggcgctc gcgcgcgcgt ccgcgcgcgc ggatctcggc
     4201 gtcgcggccg atacgctgca cggcatggcg ctctggatcg acggccacta cacgctcgcg
     4261 ctcgacgcgt tcgacgcggc gctcgccgcg tacgatccgc gccgcgacgg cgatcaccgg
     4321 cacgtgttcg gcctggacac gcgcgcgtgg gcgcaatccg cgcgcgcgtg cgtgctgtgg
     4381 ggcatcgacg acgatgtcgc gcgcacgctc gcgctcgcgc gcgacgcggt tcaactggcg
     4441 acctgcaccg atcatctgcc gacgatcggc ctgacgatga tgtatctcgc gcgaatgcag
     4501 caatgcgtgg gcgaccggga aggcgcgcgc gcgacggccg acgcggtgct gcggctgtcg
     4561 cgctgccacg ggctcaacgc agtcgagcgc tacgcggccg tcgtgcgggc gtggtgcgac
     4621 ggcgatcgcg acgcggcgcg cgcgaacgtc gatgcgctgc gcgcgtcggg atgcatgctg
     4681 ggcctcacgt attacgcgtc ggtcgccgcc gacatcgacg ccgagcgcgg cgatgcgcgc
     4741 gccgcgctcg cgacgctcga cgaatgcctc gcgctcgccg aatcgatgga cgagcgccat
     4801 tacgtcgccg aactgctgct caagaaggcg cgctgcgtgc gcgacgcgca cggccgccgc
     4861 gcggccgacg acgcccaagc gctgtgcgcg cgggccgccg ccgtcgcgcg gcgcagcggc
     4921 atggctcgaa tcgagaggaa agcgcaggcg gagctgcgcg agctgcaacg ggaactccga
     4981 tcaaccacgg gagaagagcg atgacagacc gaagccccaa tgttccgacg tacgaccagt
     5041 ttctcgaata ccgcgcggtg atcgtgcagg cgatcgcggc ggcgtggcac gacgccgagt
     5101 ttcgcgagga actgatcgcg catccggtcg acgcgctgca caagcgtttc gactaccggt
     5161 ttccgatgaa gatgcacctg aaagtgcatg agaacagcgc gacgtggaca ccgctcacga
     5221 acggcgggtg gacgaccaac gaggtcaacg gcctcgatct cgtgctgccg ccggcgccgc
     5281 cgccggagca gcgcgcggcc gcgctcgccg cgtacaacgc gagacacatc agtctgttcg
     5341 gaccggaccg caaggagatc tgacatggct gagaacaacg ccgtccctac ccaccaatcg
     5401 ctgctcgatt ttccggaggt ctatctgcgc gcgatcgcgc tgtcatggga gaacgagcag
     5461 ttcaagcggg agctgctcgc cgatccgctg gatgcgctcg agcgctattt cgactatcgc
     5521 tgcccgtgga tcctgaatct gaaggtcgcc gaagtgccgc cggacgagtc tcattatggc
     5581 tgggacgcca agcggcagcg ctggaatctg cccgtcaaca cgttgcgcgt cggcattccg
     5641 acgccgccga agcacctcgc cgaggaaggc atcgcgctcg ccgcatacaa cgacgcgggc
     5701 ccggcgtacc tgttcacctg ctgctgagcc gttcatccgg cgagccgcgg cgcggcccgg
     5761 cgcacgttgc gcgggccgcg ccgcgcacgt cgatcgcggt atccgatacg ggggggcgat
     5821 gctcgacgac ttctcgcgcg tgctgcgttt caagccgcat ctgctggtgc gcgacgccgg
     5881 ttccggcgcg ctgtatgtgg tggacgaatt caggcgctcg gtgctgccgg gcgacgtgtt
     5941 tcccgcgatc gccgcgtgca tgcgcgatcg cctgacgatc gcgcagacgt tcgcggcgct
     6001 cgccgcgcgg ttttctcaat gggaggtgct cgccgcgctc gatcaactgg tgcggcgcgg
     6061 ctacgtgcgc gccgatgcac ccggcgagcg cgacgccgag cttgccttcc atgaacgcgc
     6121 gggcgtcgac ggcgatgcgg cgagcggcgt cgcgtcgcgg cttacggtcg ccgtcgaggc
     6181 gttcggcgtg gacccgcgcg cgcagctcga cgcgttcgcc gcatgcggga tcggcgttgc
     6241 gcccgacgcg ccgctgacgg tcgcgctcac cgacggctac gatcgcgccg aattgatcgt
     6301 ggccgccgaa cgcgcggcgg cgcgcggcgg cgcattgctc gttgtcgtgg ccgatcgcgt
     6361 ggagccgctg atcggcccgt tgctcggcgc tgcggcgggc ttggcggcat cggcgggatc
     6421 gacggcgccg acggcaccgt cgacatcgcc cgcgccgcag gacgccgccg acgcgccgcc
     6481 ctgcatcgaa tgcgtgcgct actggacggc gctgaaccat cccgtcgaga cgctgctcgc
     6541 gcgcctgcac ggcggcgacg cggcgcgcct gccgcccgcg cgcagccgtg cgagcgccgc
     6601 cgccgtcgcg gccgtcgtcg cgtcgttcgt cgagcagatc gcggtgaacg cgcagcgccg
     6661 ccgtcatgcg ggctcgcata tcgtgtcgct gcgcgtcgat acgctggcca ccgccgcgca
     6721 tcgcgtcgtc aggcggccgc aatgtccgcg ctgcgctcac gcgggatgga tgcgcgagca
     6781 ggccgagcgc ccggtgacgc tcgcgtcggc ggatgcgggc gcgcgccgcg acggcggcta
     6841 tcggacgctt gccgccgccg agctcttcaa acgctacgga catctgattt ccccggtgag
     6901 cgggccgatc gcctatctgc atccgatgcc ggggcgcaac gccggcatgc ggcacgtgta
     6961 cgtcgcgggc tacctggtgt gcccgccggg cgcgccgcgc gagaaccgtt tcgacaagct
     7021 gtgctcgggc aagggcgcga gcgacgcgca ggcgcgcgcc agcgcgctcg ccgaggcgct
     7081 ggagcgcttc agcggcgtct atcagggcga cgaggcggcg ctgcgcggca gtctcgcgca
     7141 gttgtcggca cacgcgccgc cgggcagcgg gccgatcgac gtcaacgcgc tgcagcagta
     7201 cagcgatcgc cagttcgagc ggcgcgagcg ccacaacgcg acgaccgacg acccgcgcaa
     7261 gcaggtgccg cggcgcttca cgcgcgacag cgtgatcgac tggacacccg cgtggtcgat
     7321 cgcgacgggc gcgcggcggc tcgtgccgct cgcgtactgc tatgcggaaa cgcccgcgtc
     7381 gagcggcgcc gactattgcg tgcacaaccc gaacggctgc gcggcaggcg catgcatcga
     7441 ggaagcgatc ctgcagggcc tgctcgagct cgtcgagcgc gacgcggtgg cgatctggtg
     7501 gtacaacatg ctgcgccggc cggccgtgga catcgaaagc ttcggcgatc cgtacttcga
     7561 cgcgctcgcc gccgactatg cgtcgctcgg ctggcgcttg tgggcgctcg acatcacgca
     7621 cgacctgcgc attccggtgt tcgtcgcgct cgcgcgcgaa acggcgacgg ggcgcttctc
     7681 gatcggcttc ggctgccatc cggacagccg gatcgcgctg cagcgcgcgc tcaccgaagt
     7741 gaatcaactg ctcgacgtcg gcgcggcggc gccgccgccg tgggacgtcg acaagctgcc
     7801 ggacgacgcg tttcttcatc cggatcccgc gctgccgccg gtgcgcgcgc cggcgcgcgc
     7861 gccgcacggc cgctgcgatc tgaagcgtga catcgaggat tgcgtcgcgc gcttggccgc
     7921 ggcgggcatc gatacgctcg tcgtcgacaa gacgcggccc gacatcggcc tgccggtcgt
     7981 gcaggtgatc gcacccggcc tgtgtcattt ctggccgcgc ttcggcgcgc cgcgactgta
     8041 ttcggtgccc gtcgcgcagc gctggcgcga gcggccgcgc gacgaggacg cgctcaatcg
     8101 cgcgctgctg ttcctgtagc gcgggcccgc cgccggcggg cttgcatgcg ccggcgcccg
     8161 caacgatgtc attcgacgag gagcgcacgt gacgaatcga acgccgaatc aaccgttcgc
     8221 ccgcccggcg cgttttgcgc aagcggagtg gcaggcgcgc gtgcaactgg cggccgcgta
     8281 ccggatcttc gatcatctgg gctggagcga gctgatctac aaccacatct cgctgcgcgt
     8341 gccgggcgaa gacacgcatt ttctgatcaa cccgttcggg ctgcactacc gcgaggtctg
     8401 cgcctcgaac ctcgtgaagg tcgacgtcga cggccattcg gtcggccacg cggactggcc
     8461 gttcaatccg gcaggcgtca cgttccatgc ggcgattcac gcggcgctgc ccgatgcgca
     8521 ctgcgtgatg cacgtgcaca cgacgccgac gatggccgtg tgcgcgacgc gccgcgggct
     8581 gtcgttctcc aatttctatg cggcgcaatt gcacggccgc gtcgcgtatc acgatttcga
     8641 gggcatcacc gtgcggcccg acgaaggccg gcggatcgtc gacagcgcgg ccgggcggcc
     8701 ggtgctgctg ttgcgcaatc acggcccggt cgcgatcggc cgcacgctcg cgcatgcgtt
     8761 ctcgctgatg tggctgctcc atcgcgcgtg cgaggtgcag gtcgcgacgc atgcgctcgg
     8821 cgagccgctc gagatcgacg cgccgattct cgacgcgtgc gcgcgcgatt cgctgaatct
     8881 cgatccgcgc cacggcgcgg ggcaggatgc gttcgatgcg ctgcagcgca tcgtcgaccg
     8941 gatcgatccg ggttatcgca gctgaatgcg gatgccgcga ttgttctgat caaaatcgtt
     9001 cgacggattg acttcaaata ttaagaatca attgatccgg aatgctttca ttcggaagcg
     9061 aaatttgatg gtttatgttt tgaatttcga ttgcgttcga ttattttcgg gtatgcgaga
     9121 agccgtaata cggcacttcg ttttcatgcg cggcagcgcg gatcggcaag cctgaagggc
     9181 caaggcggga aacgtgcgcg ccgcgtcagg tgcgcgccaa tgcgaaatga attgcgtcat
     9241 ccagcccaca cacccgcatc gcgatgtcgg agatgatcgc atcagatcga atcggcgcaa
     9301 atggcaatag atttggtatc cgaattttgg gcagattaat cgaatgcgtg ctcgaaatgt
     9361 tcgcggcttg tcgctttcgg tgatgtatcg atggctttcg tccccagtgg tccgtcttgc
     9421 gatgcgaacg cgcgatgcgc ccggttcgtg cgttcggccg tcgcggttgc actggcggtt
     9481 gcgttgctcg gcgcggcgct gctgtccgtc gagcggttcg gcgccgcgcg aagccgcgcg
     9541 tcggccgcga tcccggcgag catcggcgcg cgcctgagcg gctgcgcgtt catcgccgtg
     9601 cgcatcggcg cggcgctgtc gcggcgcgcg ccgtcgccgg cgcatgcggc ggcgcctggc
     9661 gttgcgcggc cggatttcga cgcgatcgag cgcgtgttcg gcccgatccg catgcgcgag
     9721 cggcgcgcgc atggcgcgac gtgcaccgcg gacgcgccgg acgcgtcgca cgcagggtgg
     9781 atcgaacccg cgcgcgcgtg ctcggccgcc gcgcatgcgg cgccggggcg cggcgccgag
     9841 ggcgcgccga acacgatgcc gaggccgtcc gaagcgggcg ccgcggcggt cccacaatcg
     9901 caaccgtacc tggacatgat cgattcgacg tttcgcgaac cggcggccat cgtgctcgct
     9961 ttgagcctgc tcggcatgat cgcgctcgca ctgctgcccg tgttccggat caggcggctc
    10021 gcgcttcgcc tcggcgaggc gcagggagcg ctcgagatga gcgaagcgcg cgcccgcgcg
    10081 gcgctcgtcg ccgtcggcga cggcgtgatc ttcaccggcc gggcggggcg cgtcgaatgc
    10141 ctgaatccgg cggcggagcg attgatcggc atgctcgccg acgattgccg cggccgtccg
    10201 ctcgtgtcga cgctgcggct gtcgcgcacg gccacgtccg cttcgtccgg cgcgttcgcc
    10261 gcgtccgccg ggctcgacgc gccggattcg ccgagctcgg ccgcctcgcc cgatgcgccg
    10321 ctcggcgatc tcgaggacgg cggcagttgc gacgcgacgc tctaccgcgc ggacggcggc
    10381 gcgatcgccg tgcgcgcgac cgcgtcgtcg atcgcgccgc cgccggggca tgcgcggcgc
    10441 gcgtgcggca gcggccgcgt gctcgtgctc aagagcctcg cgaccgagca cgagctcgtg
    10501 cgccgcctcg cgtggcagac aacgcacgat ccgctcaccg gcctggcgag ccgcgccgag
    10561 ttcgagcgtc acgttggttt cgcgctcgcc gccgacgtgc gcgagccggt cgcgctgctg
    10621 ttcgtcgatc tggatcgctt ccggatcgtc aacgatacgt gcggctacgc ggcgggcgac
    10681 gcgatgctcg cagcgctcgc cgcgcgtctc gtgtcgtgcg cggcgtcggc cgacgtcgtc
    10741 gcgcggctcg gcggcgacga attctgcgtg ctgctcgacg cccgcgacga agcgtcggcc
    10801 gtgagcgcgg ccgagcgcct gcgcgcgagc gtcgacggct tcgtgttcgt ctgggacggc
    10861 cagccgttct cggtgacggc gagcgtcggc gtcgcgctgc tcggcgggcc gggccgcgcg
    10921 ccgcgcgtcg aggatgcggt gcggctcgcc ggcatcgcgt gcgacgtcgc gaaggcgcgc
    10981 gggcgcaacc gcgtgcaact ggccgatccg cacgatcacg agctcgcgca ccacatcagc
    11041 gacgtatcgt ggtgcgcgcg cgtgaggcag gcgctcgaat acgacgattt ccgcctgtac
    11101 gtgcagccga tcgtcgatac ggcgacgcag agtgcgaccg gcctgccgcg cgcgaggcgc
    11161 ggcgagctgc tgctgcgcat gggcgcgctc ggcgagcgcg agggcgtcgc gccgcccggc
    11221 cttttcatcc gcgcggccga gcgctacggg ctcgtcaccg acatcgaccg ctgggtcgtg
    11281 cgcacggtgc tcgacgcgct cgcgcgcacg cgcagccggc gcttcagcga atacgcgatc
    11341 aatctgtcgg ggatctcgat cggcgacgag cgctttctcg actatgtgct cgaacagttc
    11401 gctcgcacgc gcgtcgcgcc cgcgctcatc tgtttcgaga tcaccgagac ggcggcgatc
    11461 gcgaacctgg ccggcgcgct gcgcttcatg cacgagctga aggcgctcgg ctgccggttc
    11521 gcgctcgacg atttcggctc cgggatggcg tcgctcagct atctgaagca actgcccgtc
    11581 gagtacctga agatcgacgg cagcttcgtg acgggcatcg cgaacgatgc cgcgagcctc
    11641 gacatcgtcg cgtcgatcaa cgacatcggc cacgcgatga attgcaagac gatcgccgag
    11701 tacgtcgaca gcgcggcgac gctgcaaaaa ctcgccgcgc tcggcgtcga ttatgcgcag
    11761 ggctactaca tcggccggcc cgtgccgtgg tgcgaggccg cgcgcgcgta gcggcgcgtc
    11821 cggcgcggcg gacggcgagc gtgcgccgac gggcggcggc gagcggccgg cggcaacggc
    11881 cggcgcgaga gcgaccgtca atagcgaccg tcaatagcga ccggagataa aggccggaga
    11941 tagagaccgg cgaggacgac gaacgacgac agccgccgtt cgccgccgtc acccgcggga
    12001 cgcggggcgc ggcgccggcc gcgcgaagat cgatacgcgc ttccgataca gcacgtatgc
    12061 gagcgtcgcg gcaaccgcgg tctcggcgat cagcacggcc gccgccgcgc cttgctcggc
    12121 gaagcacttc gcgagcggcg gcagcagcgc gacattcagc acgccggacg aaatcagcac
    12181 gcggctgaag gcggtcttca tgccgagcgg cagcatcgtc tgcacgccga acagatcggt
    12241 catcccggcc atgaacggaa tgagcgccat gcagcgcagc acgccgacgg tcggctcgta
    12301 ggtggacccg tacaggatgt gcaccgcgag cggcgcgagc gcgaagatcg cgagcgagat
    12361 cgcgagcacc atcgcgccct gcacgacgag cagcttgcgc aggaacgaca tcgcgtcctc
    12421 gcgcgcgtgg tgcatcagat agctgacgtg cggatacgcg gcggccttca gcggctgcag
    12481 caggctgatg gccgagcgga tcagcttgtc gcccgcggcg aagtagcccg ccgcgacgtt
    12541 gcccgacacg aagccgagca gcacggtgtt cgtcgacgcg tagaacgcga ctgacgtcga
    12601 cgcgagaaac acctgccagc cgcccttgag cgacgcggcg acgtcggccg cgccgatgcg
    12661 aacgaacacg acttcgcgcc gcacgatcag gtagccgaac acgagcacgc cgcacacgag
    12721 cggcacggcc gcgttgatcg cgaccgcgtc gatcaggtcg gcgggcgagc gcacgcacag
    12781 atacatcgcg ggcacgctga gcgcgcggca cgcgaacagc gtcacgctgt agatgcgcag
    12841 cttctggatg ccctggaaat accagcccgg cgtgagcgcg gcgcccaccg tcatgccgaa
    12901 gccgatcacg agcagcgtgc ggtcgatcgc gaaccgctcg atcgcgaacg tgagcgcgag
    12961 caggatcgcg aagcccgcca ccgtgatcgc ggcctgcgcg gcgaaggtcg cccagaagat
    13021 cttcgagcgc gcggcgagat cgtcgtgcgc gagcgcgatg cgcggcgtcg cggtcagatc
    13081 gaagctgtag ttcgtgaaat tgatgaagta ggtgatgac
//
