LOCUS       NZ_CP009477            28075 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Burkholderia pseudomallei MSHR2543 chromosome II, complete sequence.
ACCESSION   NZ_CP009477
VERSION     NZ_CP009477.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei MSHR2543
  ORGANISM  Burkholderia pseudomallei MSHR2543
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3205965)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.E.,
            Davenport,K.W., Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C.,
            Coyne,S.R., Broomall,S.M., Li,P.E., Teshima,H., Gibbons,H.S.,
            Palacios,G.F., Rosenzweig,C.N., Redden,C.L., Xu,Y., Minogue,T.D. and
            Chain,P.S.
  TITLE     Complete genome sequences for 59 burkholderia isolates, both
            pathogenic and near neighbor
  JOURNAL   Genome Announc 3 (2), e00159-15 (2015)
   PUBMED   25931592
  REMARK    Erratum:[Genome Announc. 2016 Apr 21;4(2):e00313-16. doi:
            10.1128/genomeA.00313-16. PMID: 27103731] Publication Status:
            Online-Only
REFERENCE   2  (bases 1 to 3205965)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.,
            Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C., Coyne,S.R.,
            Broomall,S.M., Li,P.-E., Teshima,H., Gibbons,H.S., Palacios,G.F.,
            Rosenzweig,C.N., McMurry,K., Redden,C.L., Xu,Y., Currie,B., Mayo,M.,
            Minogue,T.D. and Chain,P.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-SEP-2014
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; Allpaths v.
            44837; Phrap v. SPS - 4.24; HGAP v. 2.2.0
            Genome Coverage                   :: 463x
            Sequencing Technology             :: Illumina; PacBio, 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000959225.1-RS_2024_06_16
            Annotation Date                   :: 06/16/2024 14:42:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,715
            CDSs (total)                      :: 6,638
            Genes (coding)                    :: 6,472
            CDSs (with protein)               :: 6,472
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 166
            CDSs (without protein)            :: 166
            Pseudo Genes (ambiguous residues) :: 0 of 166
            Pseudo Genes (frameshifted)       :: 85 of 166
            Pseudo Genes (incomplete)         :: 110 of 166
            Pseudo Genes (internal stop)      :: 20 of 166
            Pseudo Genes (multiple problems)  :: 39 of 166
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:58:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2683967
            Orig. end                         :: 2712042
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009477.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The DNA was obtained from USAMRIID.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28075
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="16"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..28075
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28075
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:18075](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18075)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            1793..2506
                     /locus_tag="BG16_RS10760"
                     /old_locus_tag="BG16_5829"
     CDS             1793..2506
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019255914.1"
                     /locus_tag="BG16_RS10760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5829"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_045587532.1"
                     /transl_table=11
                     /translation="MSTPSAAAKFDPARAAQYAEQSRIALAGYDACHDLAACMLASAIP
                     AEAHAAQVLVAGAGGTAREIAALAGLAPGWRFTAADPSRPMLDLANANVAAAGLDARVT
                     THLGYVDDLPADARFDGATLIGVLHHVAGDGAKAALLRSIARRLKPGAPLVVAGNYRRY
                     AEHPRLLSAWAQRWRMHGATPEEVARKLATILRGADPPASEDAVHALLDAAGFREPVRF
                     FASLFWGAWIAMRGA"
     gene            2855..3310
                     /locus_tag="BG16_RS10765"
                     /old_locus_tag="BG16_5830"
     CDS             2855..3310
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010110174.1"
                     /locus_tag="BG16_RS10765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5830"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_004190434.1"
                     /transl_table=11
                     /translation="MSVESVRQFLAEKAPDIDVIALSESSSTMTLSAAWDIKPAQIAKT
                     LAMKVGDAHVLLVSCGDSRLDNQKIKAALGGKAKMLSAEETVAVTGHPVGGVCPFGLPA
                     PLPVYCDVMLKSYEFVVPAAGSTHAALRIDPVRLAELVEAEWVDVCK"
     gene            complement(3375..4613)
                     /locus_tag="BG16_RS10770"
                     /old_locus_tag="BG16_5831"
     CDS             complement(3375..4613)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011853665.1"
                     /locus_tag="BG16_RS10770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5831"
                     /product="alpha-hydroxy acid oxidase"
                     /protein_id="WP_004540515.1"
                     /transl_table=11
                     /translation="MANVGKAWNIDDLRKMARKRVPKYFFDYLDGGANSETTMRANEND
                     FARWRLRQKVLTGAQSRVAGLGATYLGAEHRLPILLGPVGFAGMYWSRGEIAAGRAADD
                     AGIGQCLSTFSICSLEDVAAARSGPLYFQLYMFRDRDLTEDILARCRLANVDAVFLTVD
                     TCYIPIRERDARNGFRADTRLSARGVWSMLKRPGWCVGALSHGVPRIGNVLRYPELGAS
                     LLEQSAAVGRMIETRLSWADVKWLRARWPGRIVIKGILDPDDARRAVDEGVDGILISNH
                     GGRQLDPAPSVMDVLPEIAEAVGKRTEILMDGGVRRGADVIKALALGASAVSIGRAYVY
                     GLGAAGEKGVSRCLELLKGEMLPALNMMGFESIAELRAAGKSALRMAVPVHGATAVVEG
                     AEGGARRLTESVL"
     misc_feature    4567..4581
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.52"
                     /tool="antismash"
     misc_feature    complement(4569..4582)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.99"
                     /tool="antismash"
     gene            4866..5276
                     /locus_tag="BG16_RS10775"
                     /old_locus_tag="BG16_5832"
     CDS             4866..5276
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195676.1"
                     /locus_tag="BG16_RS10775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5832"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_004195676.1"
                     /transl_table=11
                     /translation="MDTKHDGGSPIAERRTEGFRLLESGMPQADVARRLVVSRQSVCRW
                     AKRLAERDGRIAKAPGRPRRLNSAQCATLRAMLDDGALAAGFASPQWTLARVRKLIERE
                     FGVAYSKTGGWELLRTLGVSLQRTERHPHIAR"
     gene            complement(5518..6111)
                     /locus_tag="BG16_RS10780"
                     /old_locus_tag="BG16_5833"
     CDS             complement(5518..6111)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009907291.1"
                     /locus_tag="BG16_RS10780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5833"
                     /product="LysE family translocator"
                     /protein_id="WP_004190802.1"
                     /transl_table=11
                     /translation="MRSLVALLFAAAVVMGSPGPSTVSATAMGASYGVRRSLKYAWGLI
                     AGTVAVLLLVSTGVTAFVMSMPSAARILNIVSALYILYLAYRIATAPPLDKRAENLSSP
                     AFKGGFLLAVANPKAYIAIGAVFAGTTLVATDYGLDAAAKIVLLSVMIVIIHLGWLLAG
                     VSLSRFLHDPVASRIINVSLAAILAIVSLIALFE"
     misc_feature    complement(5551..5553)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6163..6172
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     gene            6207..7061
                     /locus_tag="BG16_RS10785"
                     /old_locus_tag="BG16_5835"
     CDS             6207..7061
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525118.1"
                     /locus_tag="BG16_RS10785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5835"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_004529061.1"
                     /transl_table=11
                     /translation="MNDCARDIAPDRDQIRIGSGAPGIERVEAHFLDHAFTPHRHDTYA
                     IGITLSGLQTFGYLGEIHHCLPGQCHILHPDELHDGRAGTDEGFGYRIIYVDPALVQEA
                     LGGRMLPFVRSPIFQAPAVSEALAAGIWNLDEEIDNVSRIDIAVAVANLLTAAAAKGSA
                     PKAGPLAMVELTRIRDIIASCPREPISMDALEHASGLDRWTIARQFRRLFGTSPSRFRT
                     QRQLNLVRRLLMEGESLSTASTDAGFSDQSHMSRHFKSTYGITPGAWISAVRTRHAQHP
                     SDH"
     misc_feature    6235..6248
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            7294..7620
                     /locus_tag="BG16_RS35680"
     CDS             7294..7620
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195671.1"
                     /locus_tag="BG16_RS35680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004195671.1"
                     /transl_table=11
                     /translation="MPAAFAADRNGKNPHRPAPRACDMNAKAAALHIRRSRRSGHSFGP
                     AFNGCALNIPCRTSARGPHRFSESRYPFPNRAINQEFSDSIPAEFIGHQKFNYPKPITN
                     STIN"
     misc_feature    7629..7644
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            7803..8834
                     /locus_tag="BG16_RS10790"
                     /old_locus_tag="BG16_5836"
     CDS             7803..8834
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011853670.1"
                     /locus_tag="BG16_RS10790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5836"
                     /product="autoinducer binding domain-containing protein"
                     /protein_id="WP_004525116.1"
                     /transl_table=11
                     /translation="MARNRTVLPLERAQVDVVQERSGVVGDRRISLRVCGEATQGYLLE
                     RYHAAPGEPSFVQRVNLFDDATIASFVEHDPYSAELESLYRAVIDVPKKALKFAGRETI
                     QPEFASECVSESGLLTVMRNTILECGATNCFYHYFRIDEKTGNLKNHELLIGGTPVWSH
                     RYVHRHWYLNDPAMAHARNDTRPLRASTLAPLPHDHWLNQQAQFLGLTSNVFFPAHRRD
                     DDTIGLLHVSSSLPAAQGEEIIWRNRRTLRGLATEMLEWKVTAQRNTLAREMSLSHHEL
                     VALRLVGRGANARHVAEELKLQEHAVYQLFTSINKKMNSSHIRTSANKAKQFGFLAEGY
                     ISE"
     misc_feature    8154..8156
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8259..8261
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8901..9503)
                     /locus_tag="BG16_RS10795"
                     /old_locus_tag="BG16_5837"
     CDS             complement(8901..9503)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010120151.1"
                     /locus_tag="BG16_RS10795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5837"
                     /product="LysE family translocator"
                     /protein_id="WP_004525115.1"
                     /transl_table=11
                     /translation="MLIQDALLKMSFYVSLVLIVPGPTNTLLLSSGLKVGLRGTWHLVI
                     AEALGYVVAISLWGFFLLSVAASRPWLFGAIKLLSAAYILWLAVKMWTKSRALHELSAG
                     PISFGDLFVATLMNPKALLFASTMFPLEAFRSLSYFGWAVIVFLIVLAPIGVGWSSLGG
                     LLTSQRSWAAHTSTFMRCASLVLATFSGSLAYSVLGH"
     gene            complement(9541..9954)
                     /locus_tag="BG16_RS10800"
                     /old_locus_tag="BG16_5838"
     CDS             complement(9541..9954)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529064.1"
                     /locus_tag="BG16_RS10800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5838"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_004525114.1"
                     /transl_table=11
                     /translation="MNERGFGAWNRIERETLTERIERQVVSGDALTMARLYLKKGAFVG
                     THSHPNEQLTYILEGRLLFRYGEHLEHEVEVGPGEILHLPANVPHNALCLEDAVDLDVF
                     TPVRTDWLAPGGNRYFAGASAATSPTPVPSASR"
     gene            complement(10001..11044)
                     /gene="dmpG"
                     /locus_tag="BG16_RS10805"
                     /old_locus_tag="BG16_5839"
     CDS             complement(10001..11044)
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899155.1"
                     /locus_tag="BG16_RS10805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5839"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_004533405.1"
                     /sec_met_domain="HMGL-like (E-value: 7.5e-50, bitscore:
                     167.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILISDATLRDGNHAIRHQLSAAQIHAYARAADEAGIDVVEVGHG
                     NGLGGSSCLLGQTPIGDRLMLETARAALRTSRLGVHFIPGLGKAADISLALEIGVDVVR
                     VATHCTEANVSARFIEQTRTAGRTAFGVLMMSHMAPPDTLLAQAKLMERYGAQAVVLMD
                     SAGYSTPSLVRAKVERLVDGLDIDVGFHAHNNLGLAVANSLVALEAGARIVDACVKGFG
                     AGAGNTQLETLVAAMEREGHDTRTTFERVMTLARGTETFLNPKTPHIQPANIASGLYGL
                     FSGYVPHIQKAAQEFGVNEFELYKRLAERKLVAGQEDIIIEEASRLARERDVQRATGGV
                     RVRELSA"
     gene            complement(11041..11934)
                     /locus_tag="BG16_RS10810"
                     /old_locus_tag="BG16_5840"
     CDS             complement(11041..11934)
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529065.1"
                     /locus_tag="BG16_RS10810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5840"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_004529065.1"
                     /transl_table=11
                     /translation="MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSD
                     GLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATSAAAHKVNNRFFSDAGKFVIDLTPA
                     KVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIASRSA
                     GIATRENIDEYMTTTEYALAKFSGAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRV
                     RASVADMVEKVREYVPGYRLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAAL
                     AVASHRHATARLGATQ"
     gene            complement(11931..12779)
                     /locus_tag="BG16_RS10815"
                     /old_locus_tag="BG16_5841"
     CDS             complement(11931..12779)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Thioesterase (25-243). E-value: 1e-43.
                     Score: 142.3. Matches aSDomain:
                     nrpspksdomains_BG16_RS10815_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529066.1"
                     /locus_tag="BG16_RS10815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5841"
                     /product="thioesterase domain-containing protein"
                     /protein_id="WP_004525111.1"
                     /sec_met_domain="Thioesterase (E-value: 2e-43, bitscore:
                     146.5, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.4e-08, bitscore:
                     33.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAREAAAAAESPWLIVHEARNARVRLFCFHYAGATASIFRTWPG
                     GLPDWIEVVAVQLPGREYRLGEPLIEHAEPIVEALADIVPPLLDLPYAFFGHSMGALIA
                     FDLAHLLRARGFAQPLLFVASGRSAPRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALIA
                     DPALRELWLPRLRADLTISATYRYVGPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIG
                     AVRYVGFSGGHFFMHGEEAGVLAEVRRELERVLARAAQDEPNGMREPAARMSHLTEESG
                     T"
     aSDomain        complement(12051..12704)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG16_RS10815_Thioesterase.1"
                     /evalue="1.00E-43"
                     /label="BG16_RS10815_Thioesterase.1"
                     /locus_tag="BG16_RS10815"
                     /protein_end="243"
                     /protein_start="25"
                     /score="142.3"
                     /tool="antismash"
                     /translation="RLFCFHYAGATASIFRTWPGGLPDWIEVVAVQLPGREYRLGEPLI
                     EHAEPIVEALADIVPPLLDLPYAFFGHSMGALIAFDLAHLLRARGFAQPLLFVASGRSA
                     PRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALIADPALRELWLPRLRADLTISATYRYV
                     GPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAVRYVGFSGGHFFMHGEEAGV"
     CDS_motif       complement(12447..12509)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS10815_0001"
                     /evalue="1.00E-07"
                     /label="NRPS-te1"
                     /locus_tag="BG16_RS10815"
                     /protein_end="111"
                     /protein_start="90"
                     /score="24.4"
                     /tool="antismash"
                     /translation="PYAFFGHSMGALIAFDLAHLL"
     gene            complement(12776..13720)
                     /locus_tag="BG16_RS10820"
                     /old_locus_tag="BG16_5842"
     CDS             complement(12776..13720)
                     /EC_number="2.6.1.42"
                     /GO_function="GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (51-286). E-value: 1.5e-38.
                     Score: 124.8. Matches aSDomain:
                     nrpspksdomains_BG16_RS10820_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529067.1"
                     /locus_tag="BG16_RS10820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5842"
                     /product="branched-chain amino acid transaminase"
                     /protein_id="WP_004529067.1"
                     /transl_table=11
                     /translation="MKSSYVWKNGELVPWEHAQVHVMSHALHYGTSVFEGVRAYEIGEK
                     AAILCGREHFERLLFSCKVARIASPMSVGQWMEATVETLRANGQRSAYIRPLVYRGAGE
                     SLGLDARQCPAEALLITTPWGAYLGDEALQQGVDVQVSSWRRNGAGAASTLAKIGGQYV
                     NGQAIVMEAHENGMSEGIALDTNGFVSEGSGENVFLVYKNEIFTPSIGSSILSGITRHC
                     VIRIARDLGYTVTETSIPREMLYLADEIFFTGTAVEICPVRSVDRMPVGSGKRGAVTKA
                     IQDQYFGIVRGTHADKWNWLTPVAVPSRDGARA"
     aSDomain        complement(12863..13567)
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG16_RS10820_Aminotran_4.1"
                     /evalue="1.50E-38"
                     /label="BG16_RS10820_Aminotran_4.1"
                     /locus_tag="BG16_RS10820"
                     /protein_end="286"
                     /protein_start="51"
                     /score="124.8"
                     /tool="antismash"
                     /translation="REHFERLLFSCKVARIASPMSVGQWMEATVETLRANGQRSAYIRP
                     LVYRGAGESLGLDARQCPAEALLITTPWGAYLGDEALQQGVDVQVSSWRRNGAGAASTL
                     AKIGGQYVNGQAIVMEAHENGMSEGIALDTNGFVSEGSGENVFLVYKNEIFTPSIGSSI
                     LSGITRHCVIRIARDLGYTVTETSIPREMLYLADEIFFTGTAVEICPVRSVDRMPVGSG
                     KRGAVTKAIQDQY"
     misc_feature    13688..13703
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(13735..14418)
                     /locus_tag="BG16_RS10825"
                     /old_locus_tag="BG16_5843"
     CDS             complement(13735..14418)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006027931.1"
                     /locus_tag="BG16_RS10825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5843"
                     /product="RraA family protein"
                     /protein_id="WP_004525109.1"
                     /transl_table=11
                     /translation="MAQWNSDDELFALMRAELSTCPVSDVMEVLGFAYPMLPPEIRPLR
                     RDMVMIGRAMPVQDEPPVPHGGLKRYDAKPFGLLFESVEALRPGEVYIASGGPTAVARL
                     GDLLVTRARNLGAAGVVLHAHVRDANAILDLNLPAFAHGTYAYGLQGRHNVVDYRCSIT
                     VGHVRIRPGDLIFGDGDGVCVIPREAEREVITRAIAKNRLERKVRGAIAEGRSVVEAFN
                     QYNVM"
     gene            complement(14426..15223)
                     /locus_tag="BG16_RS10830"
                     /old_locus_tag="BG16_5844"
     CDS             complement(14426..15223)
                     /NRPS_PKS="Domain: Thioesterase (27-252). E-value: 5.3e-49.
                     Score: 159.6. Matches aSDomain:
                     nrpspksdomains_BG16_RS10830_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009978083.1"
                     /locus_tag="BG16_RS10830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5844"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_004525108.1"
                     /sec_met_domain="Thioesterase (E-value: 8.9e-46, bitscore:
                     154.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGADMNACEARWFLFGADERKPDARIRLFCFHYAGSGGSIFRHW
                     GEALPDDVELVAVQMPGRENRLNEPLLYSMDEAVPPLVDALAPLLDRPFAFFGHSTGAL
                     IGFEVARVLRARGYPQPRLLIASAQNAPDVKPEVIRHRLSDAEFVEVLRGCNGTPDAIL
                     QDPALLELLLPRIRADGAVFETYRYERQAPLDCRIVVFHGAADALVHDAGLARWAGETQ
                     HSFARYRFAGDHFFIHDEEASVLDHINRELEPLLSDASSTLIG"
     aSDomain        complement(14468..15142)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG16_RS10830_Thioesterase.1"
                     /evalue="5.30E-49"
                     /label="BG16_RS10830_Thioesterase.1"
                     /locus_tag="BG16_RS10830"
                     /protein_end="252"
                     /protein_start="27"
                     /score="159.6"
                     /tool="antismash"
                     /translation="RLFCFHYAGSGGSIFRHWGEALPDDVELVAVQMPGRENRLNEPLL
                     YSMDEAVPPLVDALAPLLDRPFAFFGHSTGALIGFEVARVLRARGYPQPRLLIASAQNA
                     PDVKPEVIRHRLSDAEFVEVLRGCNGTPDAILQDPALLELLLPRIRADGAVFETYRYER
                     QAPLDCRIVVFHGAADALVHDAGLARWAGETQHSFARYRFAGDHFFIHDEEASVLDHIN
                     REL"
     CDS_motif       complement(14585..14602)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS10830_0004"
                     /evalue="2.30E+01"
                     /label="NRPS-beforete1"
                     /locus_tag="BG16_RS10830"
                     /protein_end="213"
                     /protein_start="207"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="LVHDAG"
     CDS_motif       complement(14612..14632)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS10830_0003"
                     /evalue="3.80E+01"
                     /label="NRPS-beforete1"
                     /locus_tag="BG16_RS10830"
                     /protein_end="204"
                     /protein_start="197"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="IVVFHGA"
     CDS_motif       complement(14885..14950)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS10830_0002"
                     /evalue="8.30E-06"
                     /label="NRPS-te1"
                     /locus_tag="BG16_RS10830"
                     /protein_end="113"
                     /protein_start="91"
                     /score="18.3"
                     /tool="antismash"
                     /translation="RPFAFFGHSTGALIGFEVARVL"
     CDS_motif       complement(15116..15139)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS10830_0001"
                     /evalue="1.30E-02"
                     /label="NRPS-beforete1"
                     /locus_tag="BG16_RS10830"
                     /protein_end="36"
                     /protein_start="28"
                     /score="8.7"
                     /tool="antismash"
                     /translation="LFCFHYAG"
     gene            complement(15227..16132)
                     /locus_tag="BG16_RS10835"
                     /old_locus_tag="BG16_5845"
     CDS             complement(15227..16132)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004533401.1"
                     /locus_tag="BG16_RS10835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5845"
                     /product="chlorinating enzyme"
                     /protein_id="WP_004525107.1"
                     /sec_met_domain="PhyH (E-value: 1.4e-35, bitscore: 120.8,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKRFHLSEAEKKFFYENGYAGPFTLYEPEEMTRVWEEVRMDLLD
                     TAKAAFPNSKLNYDRHLDMLSLNQIISHPKIVDRISSILGPDVLSWRTEWFPKYPGDEG
                     TDWHQAESFVEFEGTEKLEPTAAEEGRPWELTAWIAMSEATKENGCLKLMPGSHRTWFF
                     DEKRNIPFEPENFNKRVLDDGQKSGFYGYDYEKLKLDPSWKPDEARAVHMEVKPGQFFI
                     FTSRCMHGSNPNTSKDSVRFGWATRFVPTHVKVYAGQDSFHHFGEVLPLDRYSTVLVAG
                     EDRYGHNRVTKPLAAVAALA"
     misc_feature    16117..16128
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.79"
                     /tool="antismash"
     gene            complement(16229..16489)
                     /locus_tag="BG16_RS10840"
                     /old_locus_tag="BG16_5846"
     CDS             complement(16229..16489)
                     /NRPS_PKS="Domain: PCP (3-72). E-value: 2.6e-13. Score:
                     42.0. Matches aSDomain: nrpspksdomains_BG16_RS10840_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525106.1"
                     /locus_tag="BG16_RS10840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5846"
                     /product="acyl carrier protein"
                     /protein_id="WP_004525106.1"
                     /sec_met_domain="PP-binding (E-value: 8.2e-11, bitscore:
                     39.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTETMLIQILESVIGVKKVTGDTRFLDIGGNSLNLVEVLKQIKA
                     KTGVAPSPRLFFDKTRSTVAALSAEIDTLREMSSAAAPVAG"
     aSDomain        complement(16274..16480)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG16_RS10840_PCP.1"
                     /evalue="2.60E-13"
                     /label="BG16_RS10840_PCP.1"
                     /locus_tag="BG16_RS10840"
                     /protein_end="72"
                     /protein_start="3"
                     /score="42.0"
                     /tool="antismash"
                     /translation="ETMLIQILESVIGVKKVTGDTRFLDIGGNSLNLVEVLKQIKAKTG
                     VAPSPRLFFDKTRSTVAALSAEID"
     gene            complement(16486..18075)
                     /locus_tag="BG16_RS10845"
                     /old_locus_tag="BG16_5847"
     CDS             complement(16486..18075)
                     /NRPS_PKS="Domain: AMP-binding (9-418). E-value: 2.1e-94.
                     Score: 308.3. Matches aSDomain:
                     nrpspksdomains_BG16_RS10845_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009978089.1"
                     /locus_tag="BG16_RS10845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5847"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_041222224.1"
                     /sec_met_domain="AMP-binding (E-value: 4.2e-105, bitscore:
                     349.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARHIVQAIQSHAFATPYKCALSDSRGDLGYADLDSFSTRFAMRL
                     QDLGCRPGDRVVMLASRRALLVAAIIGVFKAGCVHVPLDPRMPADRLRYILHDVAPTLV
                     IADEDLIDAIEHALPVAAPIVPVTELERLLDDADSPRLDALVQPLPLPPLDERAIAYCI
                     YTSGSTGRPKGVLINHRSIADFFEGTRAVYDVTAQSRCASFSPLNFDVYLMDMLFPLAQ
                     GASLYVHDDVNAPDLLFDAIRAHDVTHFSAWGMMLGLIAQAEEFESAPLPHLKTILTGT
                     DVPDVKTVQRWLRKNAGVQVINAYGPTEATCAATAHVIREIEPERRTLYPIGKPLEHVL
                     ALLVDEGGNRITAPGVPGELMIGGTQVMQGYWNLPEETAARLVRLDGVPFYRTGDVCAY
                     LADGSLYYMGRKDNEVKIGGYRIHLSEIQRVINSVPHVYGSEVVLLESRYGETLLAAGV
                     LLERGAPLDADCKADEIRQRLAAELPAYMVPRHVKVLEQFPQLSSGKTDRKALLSILQQ
                     RINESNQEEVNP"
     CDS_motif       complement(16792..16857)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS10845_0004"
                     /evalue="2.80E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="BG16_RS10845"
                     /protein_end="428"
                     /protein_start="406"
                     /score="26.1"
                     /tool="antismash"
                     /translation="YMGRKDNEVKIGGYRIHLSEIQ"
     aSDomain        complement(16822..18048)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG16_RS10845_AMP-binding.1"
                     /evalue="2.10E-94"
                     /label="BG16_RS10845_AMP-binding.1"
                     /locus_tag="BG16_RS10845"
                     /protein_end="418"
                     /protein_start="9"
                     /score="308.3"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="QSHAFATPYKCALSDSRGDLGYADLDSFSTRFAMRLQDLGCRPGD
                     RVVMLASRRALLVAAIIGVFKAGCVHVPLDPRMPADRLRYILHDVAPTLVIADEDLIDA
                     IEHALPVAAPIVPVTELERLLDDADSPRLDALVQPLPLPPLDERAIAYCIYTSGSTGRP
                     KGVLINHRSIADFFEGTRAVYDVTAQSRCASFSPLNFDVYLMDMLFPLAQGASLYVHDD
                     VNAPDLLFDAIRAHDVTHFSAWGMMLGLIAQAEEFESAPLPHLKTILTGTDVPDVKTVQ
                     RWLRKNAGVQVINAYGPTEATCAATAHVIREIEPERRTLYPIGKPLEHVLALLVDEGGN
                     RITAPGVPGELMIGGTQVMQGYWNLPEETAARLVRLDGVPFYRTGDVCAYLADGSLYYM
                     GRKDNEVKIG"
     CDS_motif       complement(16933..17016)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS10845_0003"
                     /evalue="5.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="BG16_RS10845"
                     /protein_end="381"
                     /protein_start="353"
                     /score="41.1"
                     /tool="antismash"
                     /translation="PGVPGELMIGGTQVMQGYWNLPEETAAR"
     CDS_motif       complement(17539..17598)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS10845_0002"
                     /evalue="3.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="BG16_RS10845"
                     /protein_end="179"
                     /protein_start="159"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYCIYTSGSTGRPKGVLINH"
     misc_feature    complement(17629..17631)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       complement(17824..17862)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS10845_0001"
                     /evalue="1.10E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="BG16_RS10845"
                     /protein_end="84"
                     /protein_start="71"
                     /score="12.5"
                     /tool="antismash"
                     /translation="GVFKAGCVHVPLD"
     gene            complement(18123..18407)
                     /locus_tag="BG16_RS44270"
     CDS             complement(18123..18407)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529069.1"
                     /locus_tag="BG16_RS44270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004544618.1"
                     /transl_table=11
                     /translation="MDAATNDAHSRRRRAVRIEPASCAFASVARRVPRDPAPWAVRRRT
                     GGRYKKATSSLRESSKQSNDEGPVVVGGRTCSANAHAVPSGRLPVRNAA"
     misc_feature    18524..18539
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            complement(18702..18935)
                     /locus_tag="BG16_RS44275"
     CDS             complement(18702..18935)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009940991.1"
                     /locus_tag="BG16_RS44275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004525104.1"
                     /transl_table=11
                     /translation="MTSGRAARDPASRTHRVTICAGMPGRGLVRAFPRKTAEASPRRRA
                     VDRGDTGFRRTFHRRSMKRFGRHREHRVNGGR"
     misc_feature    complement(19230..19245)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.81"
                     /tool="antismash"
     gene            complement(19310..19675)
                     /locus_tag="BG16_RS10855"
                     /old_locus_tag="BG16_5848"
     CDS             complement(19310..19675)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004544760.1"
                     /locus_tag="BG16_RS10855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5848"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_004525103.1"
                     /transl_table=11
                     /translation="MSTRAEGRTSRAPLKRAQLRDCAEVFAALGDETRLRIVAALCAGT
                     ALSIAQITAGTDITRQSVTQHLLVLAQAGLVHDVKVGRERRWSFDPARIDAARAALDAI
                     GRQWDQALLRLRQAVEG"
     gene            complement(19659..20120)
                     /locus_tag="BG16_RS10860"
                     /old_locus_tag="BG16_5849"
     CDS             complement(19659..20120)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (6-147). E-value:
                     5.8e-10. Score: 31.7. Matches aSDomain:
                     nrpspksdomains_BG16_RS10860_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010120211.1"
                     /locus_tag="BG16_RS10860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5849"
                     /product="SRPBCC family protein"
                     /protein_id="WP_004525102.1"
                     /transl_table=11
                     /translation="MNTSTDRIEKRIVLNAPRSRVWRALTNADEFGAWFRVDLAGQTFE
                     AGRCVEGRITYPGYEHLVLRMRIERIEPEHRFSYHWHPAAIDPAVDYAQETPTLVVFEL
                     ADVAGGTLLTVVESGFDKLPIERRAEAFRMNDGGWGEQMTNIAAHVDAR"
     aSDomain        complement(19680..20102)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG16_RS10860_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.80E-10"
                     /label="BG16_RS10860_Polyketide_cyc2.1"
                     /locus_tag="BG16_RS10860"
                     /protein_end="147"
                     /protein_start="6"
                     /score="31.7"
                     /tool="antismash"
                     /translation="RIEKRIVLNAPRSRVWRALTNADEFGAWFRVDLAGQTFEAGRCVE
                     GRITYPGYEHLVLRMRIERIEPEHRFSYHWHPAAIDPAVDYAQETPTLVVFELADVAGG
                     TLLTVVESGFDKLPIERRAEAFRMNDGGWGEQMTNIA"
     gene            complement(20267..20920)
                     /locus_tag="BG16_RS10865"
                     /old_locus_tag="BG16_5850"
     CDS             complement(20267..20920)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015603248.1"
                     /locus_tag="BG16_RS10865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5850"
                     /product="DUF1345 domain-containing protein"
                     /protein_id="WP_004529073.1"
                     /transl_table=11
                     /translation="MTFYPQVLRNRPRMVIAVAAGVALGLLFPYPLRPFARVLIGWDCT
                     IWLYLVLMWVRMVRAHHHKVREIAMREDENATMVLTIICFATVASIAAIVLELVSAKSV
                     GFRSGLGHYAVTGATMFGAWFLIPTIFTLHYARLYYLSPKEARAMAFPDRELEPDYWDF
                     LYFSFTIAVASQTADVSLRGRSIRRAALAQSILSFYFNMAVLGLSVNVAAGLLS"
     misc_feature    complement(20849..20851)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21042..21776
                     /locus_tag="BG16_RS10870"
                     /old_locus_tag="BG16_5851"
     CDS             21042..21776
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525100.1"
                     /locus_tag="BG16_RS10870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5851"
                     /product="metallophosphoesterase"
                     /protein_id="WP_004540458.1"
                     /transl_table=11
                     /translation="MDTAPLIRRHTANHAGRDFVVGDLHGCVDPLRALLHTVRFDPARD
                     RLFSVGDLVDRGAQSEAALALLERPWFHCVLGNHEDVLCSVADGRLPMSVWQRIGGEWA
                     ADLPAATLARHARRLRELPLVRVVGEGDARFNVLHAEFFGSDADLDRGDYAPDVITRLL
                     WGRELAYGRTDPAARQAGLSTTYCGHTPMHDVVRIGAQTFVDTGAFDPSGRLTLLDAKS
                     GESWSMSVAAARHQGAADVPLP"
     gene            complement(21877..22584)
                     /locus_tag="BG16_RS10875"
                     /old_locus_tag="BG16_5852"
     CDS             complement(21877..22584)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019255919.1"
                     /locus_tag="BG16_RS10875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5852"
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="WP_004552047.1"
                     /transl_table=11
                     /translation="MGVTSPERQTNWPTASLDWAPAYRVIPTRFPAINLFDRVASAEDF
                     DALYALEALTNDRVRTEVGMLDLVPPQERRFGPGYGPIMAAFTHLNPNGSRFSDGSYGV
                     FYCARARNTAIAETRYHTSLFLAATKEPPMRQQMRLYTVAAQGEVADVRAWRERDPALL
                     DLVDYSAGQALGRAVRDAGGAGIAYPSVRDPGGECLAAFRTTLLHDCRHAAYLEYNWNG
                     AAIDAVFELNQVG"
     gene            complement(22575..22994)
                     /locus_tag="BG16_RS10880"
                     /old_locus_tag="BG16_5853"
     CDS             complement(22575..22994)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895626.1"
                     /locus_tag="BG16_RS10880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5853"
                     /product="MbcA/ParS/Xre antitoxin family protein"
                     /protein_id="WP_004525097.1"
                     /transl_table=11
                     /translation="MSRPALKPFSTPPAATVEQMSAAGLRAFFNIARDWNLSTDEQLVL
                     LGSPGRSTFFKWKASPQTARLTHDTLERLSLVLGIYKALQILLPQPAAADSWVKRPNDA
                     APFNGKRALDRMLAGNVSDLVAVRQYLDAARGGWA"
     misc_feature    22966..22977
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.06"
                     /tool="antismash"
     misc_feature    23045..23058
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.41"
                     /tool="antismash"
     gene            complement(23725..24633)
                     /locus_tag="BG16_RS10885"
                     /old_locus_tag="BG16_5854"
     CDS             complement(23725..24633)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020415508.1"
                     /locus_tag="BG16_RS10885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5854"
                     /product="metal-dependent hydrolase"
                     /protein_id="WP_004525095.1"
                     /transl_table=11
                     /translation="MNQPAKSTDPVSVMPVRRDLRFNLPVERATDWHGQGSQVSHFFNA
                     LSLLFPAGERFFMDSVRNYRDRIDDPVLKKQVLGFIGQEAMHTREHVEYNELMHANRLP
                     ARTVDRRVWKVTGWMKKVLPHSVQLAHTVAAEHYTAMLANWLLSEPAALAGSHEGYKQM
                     WLWHALEETEHKAVSFDVWNTVMKPGPKRYLIRIGVYLLTTMTFWPNVFLIHSQLIRWD
                     RKSDKSVRGLWRVVSLLYGPRHGMFPAIAREWLSFFRPDFHPWDYDNHHHLARVDAIVE
                     ATQAREARKLAAVELDGAKPA"
     gene            24651..24857
                     /locus_tag="BG16_RS44280"
     CDS             24651..24857
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004548817.1"
                     /locus_tag="BG16_RS44280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_038727957.1"
                     /transl_table=11
                     /translation="MVAGNVREGPRERRAARKPVAAHAGRAFARSDVSAPSRLHGHRAQ
                     KAPPGLAPAARARSLAADLYINN"
     gene            25137..25478
                     /locus_tag="BG16_RS10890"
                     /old_locus_tag="BG16_5856"
     CDS             25137..25478
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004537279.1"
                     /locus_tag="BG16_RS10890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5856"
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="WP_004525093.1"
                     /transl_table=11
                     /translation="MTVVTTESGLKYEDLTEGSGAEARAGQTVSVHYTGWLTDGQKFDS
                     SKDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGVIPPNATL
                     VFEVELLDV"
     gene            25541..26308
                     /locus_tag="BG16_RS10895"
                     /old_locus_tag="BG16_5857"
     CDS             25541..26308
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895622.1"
                     /locus_tag="BG16_RS10895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5857"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_009978103.1"
                     /transl_table=11
                     /translation="MTRLAAPSLSLRRYGAVQASDVHDFHQIVLGVDGAMTMTVDGVDE
                     RIDRRCAWLIPAGARHDYAGLADNSQLVLDLPPGSLAVPERLFERARTMAIDPGLTTLV
                     GELASRIARGPLADAASARRLHWQAAARLCGALVGELGGAPSQPAVGLDFARIDGWLRA
                     HLAQPLRIAELAAHCGFGMRRFHQLFCEAFGETPHRYLQRLRLDAAVMLLGDPKRSLTD
                     IASEVGFADQSAFTHAFTKRFGLAPGRWRSDRH"
     gene            complement(26597..27763)
                     /locus_tag="BG16_RS10900"
                     /old_locus_tag="BG16_5858"
     CDS             complement(26597..27763)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004544567.1"
                     /locus_tag="BG16_RS10900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5858"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_004544567.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 4.1e-34,
                     bitscore: 115.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHTETSIKSLQIGMHWFPERAGGLDRMYYSLVGALPSAGVAVRG
                     VVAGSERVAADTGGAIRGFGPATSSLPRRMIAARHALRDVMRIERPDVVSSHFALYTFP
                     GLDVTRGIPQVSHFQGPWADESHVEGADSLGQKVKHRLEQAVYARSSRLIVLSHAFGQI
                     LTSRYNVDPARVRVVPGCVDTAQFDLPMTPADARRKLQLPQDRPIVLAVRRLVRRMGLE
                     DLIDAVKTVRRRHPDVLLLIAGKGRLEGELRKRIDDAELGENVKLLGFVPDNHLAALYR
                     AATLSVVPTVALEGFGLITVESLASGTPVLVTPVGGLPEAVAGLSEALVLPEVGAAAIA
                     DGLAAALSGSLVLPDADACRRYARAHFDNTVIARRVAEVYEEAIRAAV"
ORIGIN
        1 acgcgatccc gcgcgcgcgc cggcgtttcg aacacgatcg ttccgtccgg cgcgccatga
       61 aacggcaacg cctgcggcga caggttcagc gcgatgctga gcgtctcgcc gtcgccgagc
      121 cgccatgcgg cgacaagcgc atcggcctcg acgccgtcgg ccgcgcgcag catgtcggcg
      181 cggcgcggcc gcacgtcgat caggcgcggc gcgatcagct tcgcgcgcac cgcgagcgcc
      241 gattgcacga aatggcgccg cgacgcgtcg cccgcggctt catcgaagat cagcggaatc
      301 tgcggcgtca gcagcgacag cgcgagcgcc gcgagatccg cctcgcgcgc gtcgcgcacg
      361 acgccgtcgg acagcacgag cgaggtcagc ggcaggccga cgtcggccat cccgccttcg
      421 ccggccggat gcgcgcgctg gaacaccgcg ccgttcgcgg tcaacgcgcg cgcgagcgca
      481 tggatcgact gatgcgtcga cacgccgtcg ccgtgcgcgc gatcgcggcg ccccgtcagc
      541 cggtacagcg cgcgctcgcc gcaaccgttc cattgcgcgt cgaaatgcgt gtcggcgagg
      601 tgcgacggat gccgctcgct gccgagcacg agatgcacga tccggtcggt cggcatcgcc
      661 gcgtgcacgc gatcggcgat ctcgcgcagc cacgcgctgt cgatgcggtc cgcctcgcgg
      721 atccgcaagc cgtcgcatcg atattcttcg agccagtaca gcgcgttgtc gcagaagaag
      781 tcgcacacct gcgggtggtc gagcgcgagc ggcggcgcct gcagcggatc gtcgcgggtg
      841 tggaagaacg gctgcgcgta gcgccgcatt tcatcggagc cgcagccgaa gcgcgcatag
      901 tcgagatcga gcagcaccgc gaggccgaaa ccgtgcgcct cgtcgatcag gcgcttgagc
      961 gcgtcgacgc cgccgtatgc ggcgatcggc gcgaacggca ggctgtcgtc gcgcgcctgc
     1021 ggcgccgcga gcaactcgag cgcggtgacg cccaactgcg cgagctgcgg caagcgctca
     1081 cggacaccgt cgtaaccgcc cgccgcgccg ggctggatcg cgtagagcgc gatctcctcc
     1141 cacggcctgc cacgccagaa cgtgtggcgc cacgtgaacg cgcgcggatc gatcacctcg
     1201 ctcggcccgt cggcgccttc cggctgcgag cgcgacgccg gatcggggat cgtcagcgcc
     1261 tcgtcgagcc gataccggta gcgcgtatgc gcgccgcaat cggcgaacgt ctcgaaccag
     1321 ccgtcgcccg cgggcgccat cggcaattca tgcaggccgc ccgcggtgtc gagcgcgagc
     1381 gtcacggccg catgcgcggg cgcccagacg cgaaagtgag tgcgtgtcgt cgcgcccgcg
     1441 gcgccgcagg gctgggcgcc gaacggcagg caatgcgagt gatgctgcgc atacggatca
     1501 tgaggacatt cggacatgat gcgctcctcc tgcgctcaga ggcatggcga agcgccgtgt
     1561 gcggcgcgca tgcgtgacgc gcgtggcccg acgaagaagg ggcacccagt atgcgccgat
     1621 tcgcattacg atgcgagatt cggcgggagg ttttaaacgt gaagcgaccc cgaaatggcc
     1681 ggtagccgcc ataccatgat ggccgctcgc cttgttgcgc gccgcgtcgg cgcttaggct
     1741 gcggtttcgc gcgccattgt cggcggcgcg attcgtcagg agtccgatcg ccatgtccac
     1801 gccgtccgcc gcagccaaat tcgatccggc gcgcgcagct caatacgccg agcaaagccg
     1861 catcgcgctc gcgggctacg acgcatgcca cgacctcgcc gcttgcatgc tcgcttcggc
     1921 gatccccgcc gaagcgcatg ccgcgcaggt ccttgttgcg ggcgcgggcg gcaccgcgcg
     1981 cgaaatcgcc gcgctcgccg gcctcgcgcc cggctggcgc ttcacggcgg ccgacccgtc
     2041 gcggccgatg ctcgatctcg cgaacgcgaa cgtcgccgcg gccggtctcg atgcgcgcgt
     2101 gacgacgcac ctcggctatg tcgacgattt gcccgccgac gcccgcttcg acggcgcgac
     2161 gctgatcggc gtgctgcacc acgtggccgg cgacggcgcg aaggccgcgc tgctgcgctc
     2221 gatcgcacgc cggttgaagc cgggcgcgcc gctcgtcgtc gcgggcaact atcgccgcta
     2281 cgccgagcat ccgcggctcc tgagcgcgtg ggcgcagcgc tggcggatgc acggcgcgac
     2341 gccggaagaa gtcgcgcgca agctcgcgac gatcctgcgc ggcgcggacc ctcccgcatc
     2401 cgaggatgcg gtgcatgcgc tgctcgacgc cgccgggttc cgcgagccgg tgcgattttt
     2461 cgcgagtctg ttctgggggg catggatcgc gatgcgcggc gcatgaacgg gcctgccggc
     2521 aacccggccc gcggcgcccg ggacccgcgc ccccccgcaa cggcggccgc gacatcgcgc
     2581 gccggcgcga gcgccgcgcg tacgcgcgcc ccgcgcggcg caaaccatgc gcggcgcgcc
     2641 gaaccgcgat cgggccgcgc tcacctcgaa cgtcatgcat cgatgactgc ccggggcgag
     2701 cttgcacaat cgttcaatac aacttgcgcc gagtgcgtta gcttatccgt tccgagggtt
     2761 caccaaagat gcgggagcaa ggatcgtcga gcctgccctt gctcccgccg ataatacaaa
     2821 agcgggcatg caggctgcac ggagggccac gaacgtgagt gttgaatcgg ttcgccagtt
     2881 cctggcggaa aaggcgccgg atatcgatgt catcgcgctg agcgaaagca gttccacgat
     2941 gacgctgtcg gcggcctggg acatcaagcc ggcgcaaatc gccaagacgc tcgcgatgaa
     3001 agtcggcgac gcacacgtat tgctcgtatc ctgcggcgat tcccgcctcg acaaccagaa
     3061 aatcaaggcc gcgctgggcg gcaaggcgaa aatgctctcc gcggaggaaa cggtcgccgt
     3121 caccggccat ccggtgggcg gcgtttgccc gttcggcctt ccggctccgt tgcccgttta
     3181 ttgcgacgtg atgttgaagt cgtacgagtt cgtcgtgccg gccgcgggct cgacgcatgc
     3241 cgcgttgcgc atcgatccgg tccgcctggc cgagctggtc gaagccgaat gggtcgacgt
     3301 ctgcaagtag cctgcgtgat gagcgccgtg cgccgccggt tgcggcgcca cggcacgcca
     3361 tcggcacgtt gacgctacag cacgctctcc gtcagtctac gcgccccgcc ctccgcccct
     3421 tcgacaaccg ccgtcgcgcc atgaaccggc accgccattc gcaacgcgga cttgcctgcg
     3481 gccctgagtt ccgcgatcga ttcaaagccc atcatgttga gcgccggcag catctcgccc
     3541 ttcagcaatt cgagacatcg cgagacgccc ttctcacccg ccgcaccgag cccatagacg
     3601 taggcgcgcc cgatcgagac cgcgctggcc ccgagcgcca gcgccttgat cacgtccgca
     3661 ccgcgccgca caccgccgtc catcaggatc tcggtgcgct tgccgaccgc ctcggcgatc
     3721 tccggcaaca cgtccatcac cgacggcgcc ggatcgagtt gccggccgcc atgattcgag
     3781 atcaggatgc cgtcgacgcc ctcgtcgacc gcgcgccgcg cgtcgtctgg atcgagaatc
     3841 cccttgatga cgatcctgcc gggccagcgc gcgcgcagcc acttgacgtc ggcccaggac
     3901 aagcgcgtct cgatcatccg gccgaccgcc gcggattgct cgagcaacga tgcgccaagc
     3961 tccggatagc gcagcacgtt gccgatcctc ggcacgccat gggacaacgc accgacgcac
     4021 cagcccgggc gcttgagcat cgaccatacc ccgcgcgccg acaagcgcgt atcggcgcga
     4081 aacccgttgc gcgcatcgcg ttcgcgaatc gggatatagc aggtgtccac cgtcagaaag
     4141 acggcgtcga cgttcgccag ccggcagcgc gcgagaatgt cctcggtcag atcgcgatcg
     4201 cggaacatgt agagctgaaa atacagcgga ccggagcgcg ccgcggcgac atcctcgagc
     4261 gaacagatcg agaacgtcga caaacactga ccgatgcccg cgtcgtcggc agcgcgtccc
     4321 gccgcgatct cgccgcgcga ccaatacatg ccggcaaatc ccaccggccc gagcagaatc
     4381 ggaagccgat gctcggcgcc gaggtatgtc gcccccaaac ccgcaacccg gctctgcgcg
     4441 ccggtcaata ctttctgacg cagccgccag cgcgcgaaat cgttttcgtt cgcgcgcatc
     4501 gtggtttcgc tgttcgcgcc gccgtccaga taatcgaaga aatatttggg cacgcgcttt
     4561 cgcgccattt ttctcaaatc atcgatgttc caagccttgc cgacattggc catctgaatt
     4621 cttctccgtt ctccgccggc gcaccgcggg cgttcgtctt cgggcgtgcg ccggatgcgc
     4681 acgctcattg cgctcacacc ggcgcaccgc gatcaggtct tcgtcgcaat cattccgatc
     4741 cagcaggatt tccacctcga ctgcgtcatg gacattctaa tgtgatcttc atcggccttg
     4801 cgtcgctctt ttcaatcatt tagcaatccg tcacgtccat gagtttttca accgggagaa
     4861 cgcagatgga tacgaagcac gatggcggct cgccgatcgc cgaacggcgc accgaaggct
     4921 ttcgcttgct cgaatcgggc atgccgcagg ccgacgttgc gcgaaggctc gtcgtatcgc
     4981 ggcaatcggt ctgcagatgg gcgaaacggc tcgcggaacg cgacgggcgc atcgcgaagg
     5041 cgccgggacg gccacggcgg ctgaattccg cgcaatgcgc gacgcttcgc gcgatgctcg
     5101 acgacggcgc gctcgcggcg ggcttcgcaa gcccgcagtg gacgctcgcg cgagtacgca
     5161 agctgatcga acgcgaattc ggcgtcgcat acagcaagac gggcggatgg gaattgctgc
     5221 gcacgctcgg cgtctcgctg caacgaacgg aaaggcatcc gcacatcgcg cgctgaccgg
     5281 tatccggaga ttcgtgtcga cttggtgacc cgttcgcggc gcgatcgcgc cgcaagtaca
     5341 tgcctgcgtc acgcgcctat gatcggctgc cgcacgcatg cacacgccga tcgtcccgaa
     5401 cgcgttttga cgacggcaaa ccagggttcc gtttccgcgc cgtttcggtc actctgcccc
     5461 cctgcaccac gctgaaaata acgtgccgcc ttcgatgagg cctgcacgtc gagtatttca
     5521 ttcgaatagc gcaatcagcg aaacaatggc taatatcgcc gccaacgaaa cattgatgat
     5581 gcgagacgca acggggtcgt gcaaaaaccg ggacagcgat acgcccgcca atagccagcc
     5641 gagatggatg atgacgatca ttacgctgag cagaacgatc ttggccgcgg catcgagacc
     5701 gtaatcagtc gcgacgagcg tcgttcccgc aaataccgcg ccgatcgcga tatacgcctt
     5761 cggattggcg acggccagca ggaatccccc cttgaaagcg ggagacgaga ggttttccgc
     5821 ccgcttgtcg agtggcggcg cggtggcgat cctgtacgcg agatagagga tgtagagggc
     5881 cgaaacgata ttgagaatcc tcgctgcgct cggcatcgac atcacgaatg ccgtcacgcc
     5941 cgtcgacacg agcagcaata ccgccaccgt gcccgcgatg aggccccacg catacttgag
     6001 cgaccggcgc actccgtagg acgcgcccat cgcggtcgca ctgacggtgg agggcccggg
     6061 gctgcccatc accacagccg cagcgaaaag cagggccacc agagagcgca atgtctccga
     6121 aacaaggtcg acttggttta ccatcgaagc tccagcgcgc catctttttt gaatgggtag
     6181 cttatggaag cgtcagggag gctgtcttga acgattgtgc acgcgacatc gcacccgacc
     6241 gagatcaaat tcggatcgga tccggcgccc caggcatcga acgcgtggag gcgcacttcc
     6301 tcgatcatgc gttcacgccg catcgtcacg acacgtacgc gatcggcatc acgctctcgg
     6361 gcttgcaaac cttcggctat ctcggcgaaa tccaccactg cctgccggga cagtgccata
     6421 tcctgcaccc cgacgagttg cacgacggcc gcgcgggaac cgacgaaggc ttcggttacc
     6481 gaatcatcta cgtcgatccc gcgctcgtcc aggaagcgct cggcggccgc atgctgccgt
     6541 tcgttcgctc accgatcttc caggcacccg ccgtttccga ggcgctcgcg gccggcatct
     6601 ggaacctgga cgaggaaatc gacaacgtat cgcgcatcga catcgccgtc gccgtcgcga
     6661 acctgctgac ggccgccgcc gcgaagggca gcgcgccgaa agccggcccg ctcgcgatgg
     6721 tcgaattgac acgtatccgc gatatcatcg cctcctgtcc gcgcgagccg atctcgatgg
     6781 acgcgctcga gcacgcatcg ggactcgacc gctggacaat cgcccgccag ttccgacggc
     6841 tgttcggcac gagcccgagc cgctttcgca cgcagcgaca gctcaatctc gtgcgtcggc
     6901 tattgatgga aggcgaatcg ctgtcgaccg cctccaccga cgcgggcttt tccgatcaga
     6961 gccacatgtc gcggcacttc aagagtactt acggcatcac gccgggtgcg tggatttccg
     7021 ccgtgcgcac ccggcacgcg cagcacccgt cggaccacta aacacgtccg accggacggc
     7081 ggcgaaacac cctcgcgccg ctttctttcg atcgccgtgc ccgcccaaca ggcggatatg
     7141 gcgttccgtc ccagcgctcg cgcgcatacg cggcccatcc ggccgcgccc gacaccccgc
     7201 acgccgccgg ccgcatgcct gcccggcttc gaatgaacca acccgtgagg ccattctttg
     7261 cgaaccgccc gtcattcgat atccgtcgcc cggatgcccg ccgcgttcgc ggcggatcgc
     7321 aacggcaaaa acccacaccg tccggctccg cgcgcttgcg acatgaacgc gaaagcagcg
     7381 gcccttcaca tccggcgctc gcgccgctcg ggacacagct tcggcccggc cttcaatggt
     7441 tgtgcgctca acatcccctg ccggacaagc gcgcgcggcc cgcatcgctt tagcgaatcg
     7501 cgatatccct ttccgaatcg agcgatcaac caggagtttt ccgattcgat ccccgccgaa
     7561 tttattggcc accaaaaatt caattatcca aaacccatca caaacagcac gatcaattaa
     7621 aagtttgtat tgccaatcaa tatatggacg cagtaattta aaggacctat tccaacgcat
     7681 gcatccgccc cgcgcaccgc gaacgatttg ttggcgggcc tttccccatc ggcccggcgc
     7741 tccgtttggt cgcggcgatt cgtcatgaaa tccggcagtc cccgaagcat ggcttggcgc
     7801 gtatggctcg aaatcgtaca gtgttgcctc tcgaacgcgc gcaagtggac gtggtgcagg
     7861 aacgcagcgg cgtcgtcggc gataggcgaa tatcgctcag ggtgtgcgga gaggcgactc
     7921 agggatattt gctagagcga taccatgcgg caccgggcga gccttcgttc gtccaacgcg
     7981 tgaatctgtt cgacgacgcg accattgcat cgttcgtcga acacgatcct tattccgcgg
     8041 aactggaaag cttgtaccgt gcggtcatag acgtgccgaa aaaagcattg aaattcgctg
     8101 gacgcgaaac gattcaaccc gaattcgcat cggaatgcgt gagcgagagc ggtttattga
     8161 ccgtgatgcg caatacgata ctggaatgtg gcgcaacgaa ctgtttttac cattacttcc
     8221 ggatagacga gaaaaccgga aatctgaaga atcacgaatt attgatcggc ggaacgcccg
     8281 tatggtcgca ccgttatgtg catcgccatt ggtatctgaa tgatcccgcg atggcgcacg
     8341 cgcgcaacga tacgcgcccg ctgcgcgcat cgacgctcgc cccgctgccg cacgatcact
     8401 ggctgaacca gcaggcgcaa tttctcggcc tgaccagcaa tgtgtttttc cctgcgcatc
     8461 gtcgcgacga cgacacgatc ggtttgttgc acgtgagctc gtcgctgccc gccgcgcaag
     8521 gcgaggaaat catctggcgc aaccggcgca cgctgcgcgg cctcgccacc gagatgctcg
     8581 aatggaaagt cacggcgcag cgcaacacgc ttgcccgcga gatgtcgctc agccatcacg
     8641 agctcgtcgc gctgcgactc gtcggcaggg gggccaacgc gcgccacgtc gccgaggaac
     8701 tgaagctgca ggagcatgcg gtctatcagc tgttcacgtc gatcaacaag aagatgaaca
     8761 gcagccacat caggacgagc gcgaacaagg cgaagcagtt cggctttctg gcggaagggt
     8821 acatctcgga ataacggagc gccatgcgcg gcaccccgcc ggctcggtcc gtctcgcggg
     8881 cgggcggccc gcgagcggct tcagtgcccc aacaccgaat aggcaagcga ccccgaaaac
     8941 gtcgcgagca cgagcgacgc gcaacgcatg aacgtcgacg tatgcgcggc ccacgatcgc
     9001 tgcgacgtca gcagcccgcc gaggctcgac cagccgacgc cgatcggcgc gagcacgatc
     9061 aggaacacga taaccgccca cccgaagtag ctgagcgagc ggaacgcctc gagcgggaac
     9121 atcgtgctcg cgaacagcag tgctttcggg ttcatcagcg tggcgacgaa cagatcgccg
     9181 aagctgatcg gccccgcgga cagctcgtga agcgcgcggc tcttcgtcca catcttgacc
     9241 gcgagccaga ggatgtacgc ggcgctcaac agcttgatcg cgccgaagag ccagggccgg
     9301 ctcgccgcca cggagagcag gaagaagccc catagcgaga tcgcgacgac atagcccagc
     9361 gcctcggcga tcacgaggtg ccaggtgccg cgcaggccga ccttcaggcc cgacgacagc
     9421 agcaacgtgt tcgtcggccc aggtacgatc agcacgagcg acacgtaaaa cgacatcttg
     9481 agcaacgcat cctgaatgag cacggcgcct cctcggttcg tcggcttcgg taaacggtag
     9541 tcatcggctc gccgacggaa ccggcgtggg cgacgtcgcg gccgacgcgc cggcgaaata
     9601 gcggttgccg ccgggcgcga gccagtccgt ccgcaccggc gtgaacacgt cgagatcgac
     9661 cgcgtcttcg aggcacagcg cgttgtgcgg cacgttcgcc gggagatgca ggatctcccc
     9721 cggcccgacc tcgacctcgt gctcgagatg ctcgccgtaa cgaaacagca ggcgcccctc
     9781 gaggatgtag gtgagctgct cgttcggatg cgagtgcgtc ccgacgaacg cgcctttctt
     9841 cagatacagc ctcgccatcg tcagcgcgtc gcccgagacg acctgccgct cgatccgctc
     9901 ggtcagcgtt tcgcgctcga tccgattcca tgcgccaaag cctcgttcat tcaaacctgt
     9961 cacgatttcc tcctcgctcg atcgtgtgaa aggcgcgcgc tcacgcggac agctcgcgaa
    10021 cgcgcacgcc gcccgttgcg cgctgcacat cccgttcgcg cgcgagacgg cttgcctctt
    10081 cgatgatgat gtcctcctgc ccggcgacga gcttgcgctc cgcaagccgc ttgtacagct
    10141 cgaattcgtt gacgccgaat tcctgcgcgg ctttctggat atgcggcacg tagccggaga
    10201 aaaggccgta cagcccgctc gcgatgttcg ccggctggat gtgcggcgtc ttcggattga
    10261 gaaacgtctc cgtgccgcgc gcgagcgtca tcacgcgctc gaacgtcgtg cgcgtgtcgt
    10321 gcccttcgcg ctccatcgcg gcgacgagcg tttcgagctg cgtattgccc gcgccggccc
    10381 cgaagccttt cacgcatgcg tcgacgatgc gcgcgcccgc ttcgagcgcg acgaggctgt
    10441 tcgcgaccgc gagcccgagg ttgttgtgcg cgtgaaagcc gacgtcgatg tcgagaccgt
    10501 cgacgaggcg ctcgaccttc gcgcgcacga gcgacggcgt cgaatacccg gcgctgtcca
    10561 tcagcaccac tgcctgcgcg ccgtagcgct ccatcagctt cgcctgcgcg agcagcgtat
    10621 cgggcggcgc catgtgcgac atcatcagca cgccgaacgc cgtgcgtccg gccgtccggg
    10681 tctgctcgat gaagcgcgcc gacacgttcg cctcggtgca atgcgtcgcg acgcgcacga
    10741 catcgacgcc gatctcgagc gcaagcgaga tgtccgccgc cttgccgagc cccggaatga
    10801 aatgcacgcc gagccggctc gtgcgcagcg cggcgcgcgc ggtctcgagc atcaggcgat
    10861 cgccgatcgg cgtctgcccg agcaggcaag acgagcctcc gagaccattg ccgtggccga
    10921 cttcgacgac atcgatgccg gcttcgtcgg ccgcgcgcgc atacgcatgt atctgcgcgg
    10981 cgctcagttg gtgacgaatc gcatggttgc cgtcgcgcaa ggtcgcatcg ctgatcagta
    11041 tcattgtgtg gctcctagtc tggcggttgc gtgccgatgc gaggcgaccg cgagcgccgc
    11101 gcagttgatg atgtccagat tgcccgcgta ctcgggcaga tagtcgccgc gcccgcgcac
    11161 ggtgagaccg atcgtgatcc tcccctggct ttcgagcggc tcgacgacga gccgatagcc
    11221 gggcacgtat tcgcgcacct tctcgaccat gtcggcaacg cttgcgcgca cgcggtcgaa
    11281 atcgcgatag cgcgcgtacg catagagcgt cgtctgcatc cgcacaccgg gctcggccgg
    11341 attgatgttg aggatcgcct tcgtcttctt cgcaccgctg aatttcgcga gcgcgtactc
    11401 ggtcgtcgtc atgtattcgt cgatgttctc gcgcgtcgcg atgccggcgc tgcgcgacgc
    11461 gatcgccgac accacctcca ggtaatcgat ctcgtcgacc gcctgcttca gcgcgtacgc
    11521 gagcggcagg ctcgcctgcc cgccgcaggt gatcaggttc acgttctgct cggcgcccat
    11581 gtcgtccaga ttgatgcacg gcacgcacag gcggccgacc ttcgcgggcg tcagatcgat
    11641 cacgaacttg cccgcgtcgg agaagaagcg gttgttgacc ttgtgcgcgg cggccgatgt
    11701 cgcgtcgaac acgaggtcgt acgcatcctc gtgcgccttc aggaaatcga gaccgtcgct
    11761 cgatgtctcc acgttgcaac tgcgcgcgag ccgcagcccg tcgctgttcg cattgcgtcc
    11821 gacgacgaac ttcagatcga attgctcgga tgccttgact ttgaacatca gatcgagccc
    11881 gatgctgccc gagcccagga tcgccacccg cgtgcgcgat gacttgctct tcatgttccg
    11941 ctctcctccg tcaaatgact catgcgcgcc gccggctcgc gcatgccgtt cggctcatcc
    12001 tgcgcggcgc gcgcgagcac gcgctcgagc tcgcggcgaa cctcggcgag cacacctgct
    12061 tcctcgccgt gcataaagaa atggccgccg gaaaagccga catagcgcac ggccccgatc
    12121 gtctcggcga gccagccgga caaaccggcg tcgctgacga ggccgtcgtt cgagccgtgc
    12181 aacaccagca tcgggcaatc gagcggcggc ggcccgacgt agcggtatgt cgccgaaatc
    12241 gtcagatccg cgcgcagcct cggcagccac agctcgcgca gcgcgggatc ggcgatcagc
    12301 gcttccggcg tgccgttgta gtcgcgcacc gcggcgatga acgcctcgtc gggcagcgtc
    12361 tgaatgcccg catcccgcca cctgaagcgc ggcgcgctgc gccccgatgc gacgaacagc
    12421 aacggctgcg cgaagccgcg cgcgcgcagc aggtgcgcga gatcgaatgc gatcagcgcg
    12481 cccatgctgt gaccgaagaa tgcgtacggc agatcgagca gcggcggcac gatatccgcg
    12541 agcgcctcga cgatcggctc cgcgtgctcg atcagcggct cgccgagccg atactcgcgg
    12601 cccggcaatt gcaccgcgac gacttcgatc caatccggca ggccgcccgg ccaggttcgg
    12661 aagatcgacg cggtcgcgcc cgcgtagtga aagcagaaga gccgcacgcg cgcgttgcgc
    12721 gcctcatgga cgatcagcca aggcgattcg gctgcggctg cggcttcgcg cgcgctcatg
    12781 cccgtgctcc gtcgcgcgac ggcaccgcca cgggcgtgag ccagttccat ttgtccgcgt
    12841 gcgtgccgcg cacgatgccg aagtactgat cctggatcgc cttcgtcacc gcgccgcgct
    12901 tgccgctgcc gaccggcatc cggtcgaccg agcgaacggg acaaatctcg acggcggtgc
    12961 ccgtgaagaa gatttcgtcg gcgaggtaga gcatttcgcg cggaatgctc gtttcggtca
    13021 cggtatagcc gagatcgcgc gcgatccgga tcacgcagtg gcgcgtgatg ccgctcagga
    13081 tgctgctgcc gatcgacggc gtgaaaattt cgttcttgta gacaaggaac acgttctcgc
    13141 cgctgccttc gctgacgaaa ccgttcgtat cgagcgcgat gccttcgctc atcccgttct
    13201 cgtgcgcctc catcacgatc gcctgaccgt tgacgtactg gccgccgatc ttcgccagcg
    13261 tgcttgccgc tcccgcgccg ttgcgccgcc agctgctcac ctgcacgtcg acgccttgct
    13321 gcaacgcctc gtcgccgaga tacgcgcccc acggtgtggt gatgagcagc gcctcggccg
    13381 ggcactgtcg cgcgtcgagc ccgagcgatt cgcccgcgcc gcgatagacg agcggccgga
    13441 tgtacgcgct gcgctgaccg ttcgcgcgca gcgtctcgac cgtcgcctcc atccattgcc
    13501 cgacgctcat cggcgacgca atccgcgcga ccttgcagct gaacagcagg cgctcgaagt
    13561 gctcacggcc gcagaggatc gccgccttct cgccgatctc gtacgcgcgc acgccttcga
    13621 acacactcgt cccgtaatgc agcgcatggc tcatcacatg cacctgcgca tgctcccacg
    13681 gcaccagttc accgttcttc cacacgtagc tcgatttcat cgttgttgcg ctcctcacat
    13741 gacgttgtat tgattgaatg cctcgacgac gctgcgcccc tctgcgatcg cgccgcgtac
    13801 cttgcgctcg agccggttct tcgcgatcgc gcgcgtgatc acctcccgct ccgcctcgcg
    13861 cggaatcacg cagaccccgt cgccgtcgcc gaaaatcaga tcgcccgggc gaattcgcac
    13921 gtggccgacg gtgatcgagc agcgatagtc gacgacgttg tggcggccct gcagcccgta
    13981 cgcatacgta ccgtgcgcga acgccggcag gttcaggtcg agaatcgcgt tcgcgtcgcg
    14041 gacgtgcgcg tggagcacga cgcccgccgc gcccagattg cgcgcgcgcg tgacgagcag
    14101 gtcgccgagc cgcgcaaccg ccgtcgggcc gccgctcgcg atgtagactt cgcctgggcg
    14161 cagcgcctcg accgattcga acagcagtcc gaacggcttc gcgtcgtagc gcttgaggcc
    14221 gccgtgcggc acgggcggct cgtcctgcac cggcatcgcg cggccgatca tcaccatgtc
    14281 ccgccgcaac ggccggatct ccggcggcag catcgggtag gcaaacccga gcacctccat
    14341 cacgtcgctg acgggacagg tcgagagctc ggcgcgcatc agcgcgaaca gctcgtcatc
    14401 cgaattccac tgcgccattt gtctgtcatc cgattagagt ggagctcgcg tcgctcaaaa
    14461 gcggctcgag ctcgcggttg atgtggtcga gcaccgacgc ctcttcgtcg tgaatgaaga
    14521 agtgatcgcc ggcaaaccgg taccgcgcga aactgtgctg cgtctcgcct gcccagcggg
    14581 cgagccccgc gtcgtgcacg agcgcgtcgg cggcgccgtg aaagacgacg atccggcaat
    14641 cgagcggcgc ttgccgctca taccgatacg tctcgaacac cgcgccgtcc gcgcggattc
    14701 gcggcagcag cagctcgagc agtgccgggt cctgcaggat cgcgtcgggc gtaccgttgc
    14761 aaccgcgcag cacttcgacg aactccgcat ccgacaatcg atgccgaatc acctccggct
    14821 tcacgtcggg cgcgttctgc gcggacgcga tcagcaagcg cggctgcgga tagccgcgtg
    14881 cgcgcagcac ccgcgcgacc tcgaagccga tcagcgcgcc cgtgctgtgc ccgaagaacg
    14941 cgaacgggcg gtcgagcaac ggcgcgagcg cgtcgacgag cggcggcacg gcctcgtcca
    15001 tcgaatacag cagcggctcg ttcagccggt tctcccggcc cggcatctgc accgcgacga
    15061 gctcgacatc gtccggcagc gcctcgcccc agtggcggaa gatcgaaccg ccgctacccg
    15121 cgtagtgaaa gcagaacagc cggattcgcg catcgggttt ccgttcgtcg gcgccgaaca
    15181 ggaaccagcg ggcctcgcat gcattcatgt cggcgccgtc catcgcttac gcgagcgccg
    15241 cgacggcggc gagcggcttg gtcacgcggt tatggccgta gcggtcctcg cccgccacca
    15301 gcaccgtcga gtaacggtcg agcggcagca cttcgccgaa gtggtggaac gagtcctgcc
    15361 ccgcgtagac cttcacgtgc gtcggcacga agcgcgttgc ccagccgaag cgcaccgagt
    15421 ccttgctcgt gttcgggttc gagccgtgca tgcagcgcga cgtgaagatg aagaactggc
    15481 cgggcttcac ctccatgtgc accgcgcgcg cttcatccgg cttccagctc ggatcgagct
    15541 tcagcttttc gtagtcgtag ccgtagaagc ccgatttctg gccgtcgtcg agcacgcgct
    15601 tgttgaaatt ctccggctcg aacgggatat tgcgcttctc gtcgaagaac caggtgcgat
    15661 ggctgcccgg catcagcttc aggcagccgt tctccttcgt cgcctcgctc atcgcgatcc
    15721 acgcggtcag ctcccacggc cgcccttctt ccgcggccgt cggctcgagc ttctcggtgc
    15781 cttcgaactc gacgaagctt tcggcctggt gccagtcggt gccttcgtcg cccggatatt
    15841 tcgggaacca ctcggtgcgc cagctcagca cgtccggccc gaggatgctc gagatccggt
    15901 cgacgatctt cggatggctg atgatctggt tcagcgaaag catgtcgaga tggcggtcgt
    15961 agttgagctt gctgttcgga aacgccgcct tcgccgtgtc gagcaggtcc atccgcactt
    16021 cttcccagac gcgggtcatc tcctccggct cgtacagcgt gaacgggccg gcatagccgt
    16081 tctcgtagaa gaatttcttc tcggcttccg acagatgaaa acgcttttgc atatcagttc
    16141 tcctaaatat ggcgtaaaga gccatgtcct gaaaagattc cgcttgtcgc ggccgccgct
    16201 cgcgcggctc ttgcaatgcc ccgcgggatc agcccgcgac cggagccgcg gcgctgctca
    16261 tttcgcgcag cgtatcgatc tcggcgctca acgccgcgac cgtcgagcgc gtcttgtcga
    16321 aaaacagtct cggcgacggc gcgacgcccg ttttcgcctt gatctgcttg agcacttcga
    16381 cgagattgag cgaattgccg ccgatgtcca gaaaacgggt atcgccggtc accttcttga
    16441 cgccgatcac gctctccaga atctgaatca acatcgtttc ggttttcatg gattcacttc
    16501 ctcctggtta ctttcgttga tgcgctgttg caatatcgac agaagcgctt tgcgatccgt
    16561 ctttcccgat gacaactgcg gaaactgctc gagaaccttg acgtggcggg gcaccatgta
    16621 ggcgggcagc tccgccgcga ggcgctgcct gatttcgtcg gccttgcaat cggcgtcgag
    16681 cggcgcgccg cgttcgagca gcacgccggc ggcgagcagc gtctcgccgt agcgcgattc
    16741 gagcagcacc acctccgatc cgtacacgtg cggcacgctg ttgatgaccc gctggatttc
    16801 gctcaaatgg atccggtagc cgccaatctt cacttcgtta tccttgcggc ccatgtagta
    16861 gaggctgccg tcggcgagat acgcgcagac gtcgcccgtt cgatagaacg gcacgccgtc
    16921 gagacgcacg agccgcgccg ccgtttcttc cggcagattc cagtagccct gcattacctg
    16981 cgtgccgccg atcatcaact cgcccggcac gcccggcgcc gtgattcggt tgccgccctc
    17041 gtcgacgagc agcgccagca cgtgctcgag cggcttgccg atcgggtaga gcgtgcgccg
    17101 ctccggctcg atctcgcgga tcacgtgcgc ggtcgccgcg caggtggctt cggtcggccc
    17161 gtaggcgttg atcacctgca cgcccgcgtt cttcctgagc cagcgctgga ccgtcttcac
    17221 gtcgggcacg tcggtgccgg tgaggatcgt cttcagatgc ggcagcggcg cggattcgaa
    17281 ttcctcagct tgcgcaatca ggccgagcat cattccccac gcggaaaagt gggtgacgtc
    17341 gtgcgcgcga atcgcgtcga acagcagatc gggcgcgttc acgtcgtcgt gcacgtatag
    17401 cgacgcgccc tgcgcgagcg gaaacagcat gtccatcagg tacacgtcaa agttcagcgg
    17461 cgagaagctc gcgcagcgcg attgcgccgt gacatcgtag acggcgcgcg tgccctcgaa
    17521 gaaatccgcg atgctgcgat gattgatcag cacgcctttc gggcggccgg tcgagcccga
    17581 cgtgtagatg cagtacgcga tcgctcgctc gtcgagcggc ggcagcggta acggctgcac
    17641 gagcgcgtcg agccgcggcg aatcggcgtc gtctagaagc cgctcgagct cggtcacggg
    17701 cacgatcggc gcggcgaccg gcagcgcgtg ttcgatcgcg tcgatcagat cctcgtcggc
    17761 gatcacgagc gttggcgcga cgtcgtgcag gatgtagcga agacggtcgg ccggcatgcg
    17821 cggatcgagc ggcacatgca cgcagcctgc cttgaacacg ccgatgatcg ccgcgacaag
    17881 cagcgcgcgg cggctcgcga gcatcacgac gcgatcgccg gggcgacagc ccagatcctg
    17941 caggcgcatc gcaaaacgcg tgctgaagct gtcgagatcg gcgtagccga gatcgccgcg
    18001 ggaatcggac aacgcgcatt tgtacggcgt cgcgaacgcg tgagactgga ttgcttgaac
    18061 gatgtgtctg gccatctgac tgaatcctct ttgcgatgtc tctttacggg caccttcgag
    18121 attcaggcgg cattgcgcac cggcagacgg ccggacggca cggcatgcgc gttcgcgctg
    18181 cacgttcgtc cgccaacgac taccggcccc tcgtcgtttg actgcttgct gctttctctc
    18241 agactgctgg ttgctttttt gtatcgcccg ccggtacgcc gccgaaccgc ccatggagcg
    18301 ggatcgcgcg gcacccggcg cgcaacgctc gcgaacgcgc acgaggcagg ctcgatacgt
    18361 acggcgcggc gtcgtctgga atgcgcgtcg ttcgtcgccg catccattga ttgataggct
    18421 agatgaaatt ctccgaggaa atacttagat cacttccgga atatatgccc gcgatttcac
    18481 cggaaatgaa gaataagcac cgtaatgaaa atttaagtgt ttaattgata tttatttggt
    18541 cgcgcaatta tttttcggtg acccaataag tacgtcggcg ccacgtagtt gcgcgggtca
    18601 tatccgtatt acgacaggtg caaggtcgta tcacgcggcg tcatatccgc tctgaacgca
    18661 gccgaattgg ctatcgaggc aaatcgagga cattcgtcgc tttaacggcc accgttcacg
    18721 cggtgctcgc gatgccgccc gaagcgtttc atcgatcgac gatgaaaggt gcggcgaaat
    18781 cccgtgtcgc cgcggtcaac cgcgcgtctg cgcggcgacg cttcggccgt cttgcgcgga
    18841 aaagcgcgta cgagccctct ccccggcatg cccgcgcaaa tcgtgacccg atgcgtgcgc
    18901 gatgcgggat cgcgcgcggc gcggccgctc gtcacgaaac aggatcggtt tgtatggatt
    18961 cggcgaagcc cgccgcgaaa ggcgatttcg gtgcgcaacg tcgcccgcca gcaatgcgtg
    19021 cgatgttgtc gacggcacgg caggcacgcg cgcaggcgcg atgccggcca ccaagtatcg
    19081 gctgcggctg cgcaccggcg cgccgcgtaa cgcctccagc gcgcttgacg tgcatgcaac
    19141 acggcgcggg ccctatcgcc gaatgcgcgg cgctcgccgg cactggcgag cgccgcgcgc
    19201 attcgcccgc ggcgccggct cgcgcgcggc ggatcattcg gtcaaccgaa cgtatcggcc
    19261 agcggagcca accgcgcctg cctccgaaga cgacgcggtc acgccgccgt catccttcga
    19321 cggcctgccg cagccgcaac aatgcctgat cccactgccg gccgatcgca tcgagcgccg
    19381 cgcgcgccgc atcgatccgc gcgggatcga agctccagcg ccgctcgcgc ccgactttca
    19441 cgtcgtgcac gagccccgct tgcgcgagca cgagcagatg ctgcgtgacc gactggcgcg
    19501 tgatgtcggt gcccgcggtg atttgcgcga tcgacagcgc cgtgccggca cacagcgcgg
    19561 cgacgatccg cagccgcgtt tcgtcgccga gcgcggcgaa tacctccgcg caatcgcgca
    19621 gttgcgcgcg cttgagcggc gcgcgcgatg tccggccctc agcgcgcgtc gacatgggcg
    19681 gcgatgttcg tcatctgctc gccccaaccg ccgtcgttca ttcggaacgc ttcggcacgg
    19741 cgctcgatcg gcagcttgtc gaagcccgat tcgacgacgg tgagcagcgt gccgccagcg
    19801 acgtcggcca gctcgaacac gacgagcgtc ggcgtctcct gcgcgtagtc gacggccgga
    19861 tcgatcgcag cggggtgcca gtggtacgag aagcgatgtt ccggctcgat tcgctcgatg
    19921 cgcatccgca acaccagatg ctcatagccg ggatacgtga tgcggccttc gacgcaccgc
    19981 cccgcttcga acgtctgccc cgccagatcg acgcgaaacc acgcgccgaa ttcgtcggcg
    20041 ttcgtcagcg cgcgccacac gcgcgagcgc ggcgcgttca gcacgatccg cttttcgata
    20101 cgatcggtcg atgtgttcat atgcagcctc ctggctgcat attagacagc gcgtccgtga
    20161 aaggcaagca aatgcctgca tgtgcgggcg tcgcgcgcgc cggctcgcgc cgccggcgcg
    20221 tcgcgcgaga caaatgtcgc gccacgcaag cttcgcgcat tcgcgctcag ctcagcaggc
    20281 ctgccgccac gttgaccgac agccccagca ccgccatgtt gaaatagaag gacaggatcg
    20341 actgcgcgag cgccgcgcgc cggatcgagc gcccgcgcag cgatacgtcc gccgtctgcg
    20401 acgcgaccgc gatcgtgaac gagaagtaca ggaaatccca gtaatcgggc tcgagctcgc
    20461 gatcaggaaa cgccatcgcg cgcgcctcct tcggcgacag atagtagagc cgcgcatagt
    20521 gcagcgtgaa gatcgtcgga atcaggaacc atgcgccgaa catcgtcgcg cccgtcaccg
    20581 cgtagtggcc gaggccggag cggaacccga cgctcttcgc gctgacgagt tcgagcacga
    20641 tcgccgcgat gctcgcgacc gttgcaaaac agatgatggt cagcaccatc gtcgcgttct
    20701 cgtcttcgcg catcgcgatc tcgcgcacct tgtgatgatg cgcgcgcacc atcctcaccc
    20761 acatcagcac gagatacagc cagatcgtgc aatcccagcc gatcagcacg cgcgcgaacg
    20821 gccgcagcgg atacggaaac agcaggccta acgcgacgcc ggcggcgacc gcgatcacca
    20881 tgcgcgggcg attgcgcagc acttgcggat agaacgtcat ggtcactcgc cgaaacgatc
    20941 gaaagtcggg tgaaagaacg cgccgctgtt gcggcgcgtc gcagcgatta tcgtcacgtt
    21001 ctcccgctgc gccaagcccg gctgtgtcct aagatgggcg aatggacact gctcccctga
    21061 tccgtcgcca taccgcgaac cacgccggcc gcgatttcgt cgtcggcgat ctgcacggtt
    21121 gcgtcgatcc gctgcgcgcg ctgctgcaca ccgtgcgctt cgatccggca cgcgaccggc
    21181 tgttctcggt gggcgacctc gtcgaccgcg gcgcgcaatc ggaagcggcg ctcgcgctgc
    21241 tcgagcgccc gtggtttcat tgcgtgctcg gcaaccacga agacgtgctg tgctcggtcg
    21301 cggacggcag gctgccgatg agcgtgtggc agcgcatcgg cggcgaatgg gcggccgacc
    21361 tgccggccgc gacgctcgcg cgccatgcgc ggcggctgcg cgagttgccc ctcgtgcgcg
    21421 tcgtcggcga aggcgacgcg cgcttcaacg tgctgcacgc ggagttcttc ggcagcgacg
    21481 ccgacctcga ccgcggcgat tacgcgcccg acgtgatcac gcggctgctg tggggccgcg
    21541 agctggcgta cgggcgcacc gacccggccg cgcggcaggc cgggctgtcg accacttact
    21601 gcggccatac gccgatgcat gatgtcgtgc gcatcggcgc gcagacgttc gtcgatacgg
    21661 gcgcgttcga tccgtcgggc cggctcacgt tgctcgacgc gaagagcggc gaaagctggt
    21721 cgatgtcggt tgcggccgcg cgccaccagg gcgccgccga cgtgccgctg ccgtgacgcg
    21781 cggaagccgg acggagccga cgtacggcgc ccggcgcccg acgcgctgcg tcgagacggc
    21841 gcgcaagcgc gacggcggcg caaaccgcac gccgcctcag ccgacctgat tcagttcgaa
    21901 caccgcatcg atcgccgcgc cgttccagtt gtattcgaga tacgcggcgt ggcggcaatc
    21961 gtgcagcaac gtcgtcctga acgcggcgag gcactcgccg cccggatccc gcaccgacgg
    22021 gtacgcaata cctgcgccgc ccgcatcgcg caccgcgcgg ccgagcgcct ggccggccga
    22081 gtaatcgacg agatcgagca gcgccgggtc gcgctcacgc cacgcgcgca cgtcggcgac
    22141 ctcgccttgc gcggctaccg tgtagagacg catctgctgg cgcatcggcg gctccttcgt
    22201 cgcggcgaga aacagcgacg tgtgataacg cgtctccgcg atcgccgtat tgcgcgcgcg
    22261 ggcgcaatag aacacgccgt agctgccgtc cgaaaaacgg ctgccgttcg gattcaggtg
    22321 cgtgaacgcg gccatgatcg gcccgtagcc gggcccgaag cgccgctcct gcggcggcac
    22381 gagatcgagc atgccgactt cggtgcgcac gcggtcgttg gtcagcgcct cgagtgcata
    22441 gagcgcgtcg aaatcctcgg ccgatgcgac gcggtcgaac aggttgatcg cgggaaagcg
    22501 cgtgggaatc acgcgatagg cgggcgccca gtcgagcgac gcggtgggcc agttcgtctg
    22561 ccgttccgga gaggtcacgc ccatccgcct cgcgccgcgt cgagatattg ccgcaccgcg
    22621 acgagatcgc tgacgttgcc ggcgagcatc cggtcgagcg cgcgcttgcc gttgaacggc
    22681 gcggcgtcgt tcggccgctt gacccacgaa tcggccgcgg ccggctgcgg cagcaggatc
    22741 tgcagcgcct tgtagatgcc gagcacgagc gacaggcgct cgagcgtatc gtgcgtgagg
    22801 cgcgcggttt gcggcgacgc cttccatttg aagaacgtcg aacggccggg cgagcccagc
    22861 aaaacgagct gctcatcggt cgacagattc cagtcgcgcg cgatattgaa aaatgcgcgc
    22921 agaccggccg ccgacatttg ctcgacggtc gccgccggtg gcgtcgaaaa cggcttcagg
    22981 gcgggacggg acatggcggt tagtctcgaa atgaatctac taacaagatt agtccatttc
    23041 gggatctttg caagaaaaat aatggcggat ccgaataagc tgcggattgc aatcgttttg
    23101 atggggtcga agtgaaatgg gttggcgagc tggttttcgg gctggcgttc gagcgcaact
    23161 gtccgggcta acgccagcag ccccctgcac ggatggcatc ccgccttccc tagcgcacgc
    23221 ctgcggctac tccagccgct catcgcgcaa ttgtctccct accttcccgc gcatacgcgg
    23281 caacggcgca tcgcccgccc gtcactgcgc acgcgagaaa ggcaacgcgc tcggcagccg
    23341 ggcatcggca tgtgcccgcg acgcggagaa cggatggtgc atgcgtggca gattctttgc
    23401 agtgttccgg gtgcgcacga agacgggcca aagcgatcgg gcaagaaacg gccggagggg
    23461 aaaccggcga gaatcggata tcgcgagacc gggaagcgag caccgcgcgc aaggccgcgc
    23521 ggcagcgaat acgcccgccc ctgcccgctg cgggggcgcg cggcgaatcg gccgaccgca
    23581 gacacgagcc gacgcaagcc gtcaccgcgc ggcgcgccac gcaacctgcg cgaccggcct
    23641 ctccgtccgc gtcgacgcac cgtccggcgc gccgcagtca agcgacgcgg caccggcgcg
    23701 aacgccgccg cccgccgccg tcgtttacgc cggcttcgcg ccgtcgagct cgacggccgc
    23761 cagcttccgc gcttcgcgcg cctgcgtcgc ctcgacaatg gcgtcgacgc gggcgagatg
    23821 atgatgattg tcgtaatccc acggatggaa gtccggcctg aagaagctca gccactcgcg
    23881 cgcgatcgcc gggaacatgc cgtgacgcgg gccgtacagc aggctgacca cgcgccagag
    23941 gccgcgtacg ctcttgtccg acttgcggtc ccatcgaatc agttgcgaat ggatcaggaa
    24001 cacgttcggc cagaacgtca tcgtcgtcag caaatacacg ccgatgcgaa tcagatagcg
    24061 cttcggccca ggcttcatca ccgtgttcca gacatcgaac gacaccgcct tgtgctcggt
    24121 ttcctcgagc gcgtgccaca gccacatctg cttgtagcct tcgtgcgaac cggcgagcgc
    24181 ggcgggctcg ctcagcagcc agttggccag catcgccgtg tagtgctcgg ccgcgaccgt
    24241 atgcgcgagc tgcaccgaat gcggcagcac cttcttcatc cagcccgtga ctttccacac
    24301 gcgcctgtcg accgtgcgcg ccggcagccg gttcgcgtgc atcaattcgt tgtactcgac
    24361 atgctcgcgc gtgtgcatcg cctcctggcc gatgaagccg agcacctgtt tcttcagcac
    24421 cggatcgtcg atccggtcgc gatagttgcg caccgaatcc atgaaaaagc gctcgcccgc
    24481 gggaaacagc agcgatagcg cgttgaagaa gtgcgaaact tgcgagccct gcccgtgcca
    24541 atccgtcgcg cgctcgacgg gcaagttgaa gcgcagatcg cggcgcacgg gcatcacgga
    24601 caccgggtcc gtcgacttcg cgggttgatt catcgatgtc tcctgtctgg gtggtggcgg
    24661 gcaacgtccg cgaaggtccg cgcgagcggc gcgcggcacg caaaccggtt gcggcgcatg
    24721 ccggccgggc gttcgcgcgg tccgacgttt cggcgccgtc gcgcttgcac gggcaccgcg
    24781 cgcagaaggc gccgcccggc ctagcgccag ccgctcgcgc ccgcagcctg gccgccgacc
    24841 tttacattaa taactgaaac aatatggcga cggaccgggg ttaagcaagg cgcgtgttag
    24901 tggcggcctt ccaaacgcgc ggcgcgcggc aagcgccgcg cggcgaaccc gcaagccccg
    24961 cgcgacgggc gtttcggcgt gatcgcgcaa atcggcgtct gtcttgcaaa cgcccgtcgc
    25021 cgagcgtttt cccgcggcat cggccgacgc cgcgaaaccg gcgcgccggg aaatccggtc
    25081 gagatcgcgc ggctccccta caatagcggg tcatttcgat ccttcaggag catttcatga
    25141 cagtcgtcac caccgaatcg ggcctcaaat acgaagacct gaccgaaggc tcgggcgccg
    25201 aggcgcgcgc gggccagacg gtgagcgtgc actacacggg ctggctcacc gacggccaga
    25261 agttcgattc gagcaaggat cgcaatgatc cgttcgcgtt cgtgctcggc ggcggcatgg
    25321 tcatcaaggg gtgggacgaa ggcgtgcaag ggatgaaggt gggcggcgtg cgccgtctga
    25381 cgatcccgcc gcaactcggc tacggcgcgc gcggcgcggg cggcgtgatt ccgcccaatg
    25441 cgacgctcgt gttcgaagtc gaactgctcg acgtctgagc ccggcgccgc cccgccgccc
    25501 gtcgccccgt cgcgcgcgtt caccggccgc ccgcccgatc atgacccgcc tcgccgcccc
    25561 gagcctgtcg ctgcgccgtt acggcgccgt gcaggcgtcg gacgtgcacg atttccatca
    25621 gatcgtgctc ggcgtcgacg gcgcgatgac gatgacggtc gacggcgtcg acgagcggat
    25681 cgaccgccgc tgcgcgtggc tgattccggc cggcgcgcgg cacgattacg cgggcctcgc
    25741 cgacaacagc caactggtgc tcgacttgcc gcccggctcg ctcgcggtgc ccgagcggct
    25801 gttcgagcgc gccaggacga tggcgatcga cccgggcctc acgacgctcg tcggcgaact
    25861 cgcgtcgcgc atcgcgcgcg ggccgctcgc cgatgccgcc tcggcccggc gcctgcactg
    25921 gcaagcggcc gcgcggctgt gcggcgcgct cgtcggcgag ctgggcggcg cgccgtcgca
    25981 gcccgccgtc gggctcgact tcgcacgcat cgacggctgg ctgcgcgcgc acctcgcgca
    26041 gccgctgcgc atcgccgagc tcgccgcgca ttgcggcttc ggcatgcgcc gcttccatca
    26101 gcttttctgc gaagcgttcg gcgagacgcc gcatcgctat ctgcagcggt tgcggctcga
    26161 cgccgccgtc atgttgctcg gggatccgaa acgttcgctg accgacatcg cgagcgaagt
    26221 cggattcgcc gaccagagcg cgttcacgca cgcgttcacg aaacggttcg ggctcgcgcc
    26281 cggccgctgg cgcagcgatc ggcactgagc tttccgatgc gcgcgagcgg gccgacatcg
    26341 cacgcgacgt gaagcaccga cgccgcgacg atgcaacgac gcgacgactc gaagaaggcg
    26401 ccccatctcg cattcgccac cgcctcgcac gctcgcgtgc gcctcgcacg ttgcaccggg
    26461 gcggccgcgc cgggccgggc gcgtcgcggc aatcccgtcg ggtaacgtga aagcgcgcgg
    26521 cgccgcccgg cgcgccaggc ccggcgcccc gcacgcgatt cgcgggacac cgagcccgcc
    26581 gtgcccgccg catcggtcaa acggcggccc gaatcgcctc ctcgtagacc tccgcgacgc
    26641 ggcgcgcgat caccgtgttg tcgaaatgcg cgcgcgcgta tcgccggcat gcgtccgcat
    26701 ccggcagcac gagcgagccg gacaacgccg cggccaaccc gtccgcgatc gcggccgcgc
    26761 ccacctccgg cagcacgagc gcctccgaca ggcccgcgac cgcctccggc agcccgccga
    26821 cgggcgtcac gagcaccggc gtgccggacg cgagcgactc gacggtgatg agcccgaatc
    26881 cctcgagcgc gacggtcggc acgacgctga gcgtcgccgc acggtacagc gcggccagat
    26941 gattgtcggg cacgaaaccg agcagcttca cgttctcgcc gagctcggcg tcgtcgatcc
    27001 gtttgcgcag ctcgccttcg agccgcccct tgccggcgat cagcagcagc acgtccggat
    27061 gccggcggcg cacggtcttc accgcgtcga tcagatcctc gagccccatg cgccgcacga
    27121 gccgccgcac cgcgagcacg atcggccgat cctgcggcag ttgcagcttg cggcgcgcgt
    27181 cggcgggcgt catcggcaga tcgaattgcg cggtgtcgac gcagccgggc acgacgcgca
    27241 cgcgcgccgg atcgacgttg tagcgcgacg tgagaatctg cccgaacgcg tgcgacagca
    27301 cgatgagccg cgacgagcgg gcatagaccg cctgctcgag ccggtgcttg accttctgcc
    27361 cgagcgaatc cgcgccctcg acgtggctct cgtcggccca cgggccctgg aaatgcgaca
    27421 cctgcggaat gccgcgcgtc acgtcgagcc cagggaacgt gtacagcgcg aagtgcgacg
    27481 acacgacgtc gggccgctcg atgcgcatca cgtcgcgcag cgcatggcgc gcggcgatca
    27541 tccgccgcgg caacgacgac gtcgccggcc cgaagccgcg gatcgcgccg cccgtgtcgg
    27601 ccgcgacgcg ctcggagccc gcgaccacgc cgcgcaccgc gacgcccgcg ctcggcagcg
    27661 cgccaacgag cgagtaatac atgcgatcga gcccgcccgc tcgctcggga aaccagtgca
    27721 tgccgatctg cagcgacttg atcgacgttt cggtatgctt cattacgacc gctcctgcgt
    27781 cacgacatgc tcggtgccgg cgagcggcga cggctgcgac gactggcgca gccgccgata
    27841 caatgcgatg tactgcgcgc ccatgcgcgc ccatccgaat ccctccatca gcctgcgggc
    27901 cgcctcgccc atcgcgcggc acgcgtcgcg cgagcgcgcg aggcgctcga tcgcggccgc
    27961 gagcgcggcc ggatcgtcgg gatcgtcgag cacgatcccg cactccggcg tgatgatctc
    28021 cgcgccgccc gcggtgcgcg cggtcacgac gggcagcccc gccgccatcg cctcg
//
