LOCUS       NZ_CP009477            20609 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Burkholderia pseudomallei MSHR2543 chromosome II, complete sequence.
ACCESSION   NZ_CP009477
VERSION     NZ_CP009477.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei MSHR2543
  ORGANISM  Burkholderia pseudomallei MSHR2543
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3205965)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.E.,
            Davenport,K.W., Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C.,
            Coyne,S.R., Broomall,S.M., Li,P.E., Teshima,H., Gibbons,H.S.,
            Palacios,G.F., Rosenzweig,C.N., Redden,C.L., Xu,Y., Minogue,T.D. and
            Chain,P.S.
  TITLE     Complete genome sequences for 59 burkholderia isolates, both
            pathogenic and near neighbor
  JOURNAL   Genome Announc 3 (2), e00159-15 (2015)
   PUBMED   25931592
  REMARK    Erratum:[Genome Announc. 2016 Apr 21;4(2):e00313-16. doi:
            10.1128/genomeA.00313-16. PMID: 27103731] Publication Status:
            Online-Only
REFERENCE   2  (bases 1 to 3205965)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.,
            Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C., Coyne,S.R.,
            Broomall,S.M., Li,P.-E., Teshima,H., Gibbons,H.S., Palacios,G.F.,
            Rosenzweig,C.N., McMurry,K., Redden,C.L., Xu,Y., Currie,B., Mayo,M.,
            Minogue,T.D. and Chain,P.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-SEP-2014
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; Allpaths v.
            44837; Phrap v. SPS - 4.24; HGAP v. 2.2.0
            Genome Coverage                   :: 463x
            Sequencing Technology             :: Illumina; PacBio, 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000959225.1-RS_2024_06_16
            Annotation Date                   :: 06/16/2024 14:42:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,715
            CDSs (total)                      :: 6,638
            Genes (coding)                    :: 6,472
            CDSs (with protein)               :: 6,472
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 166
            CDSs (without protein)            :: 166
            Pseudo Genes (ambiguous residues) :: 0 of 166
            Pseudo Genes (frameshifted)       :: 85 of 166
            Pseudo Genes (incomplete)         :: 110 of 166
            Pseudo Genes (internal stop)      :: 20 of 166
            Pseudo Genes (multiple problems)  :: 39 of 166
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:58:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2347429
            Orig. end                         :: 2368038
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009477.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The DNA was obtained from USAMRIID.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20609
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="13"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20609
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20609
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10609](+)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10609
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     gene            complement(1182..1808)
                     /locus_tag="BG16_RS09455"
                     /old_locus_tag="BG16_5580"
     CDS             complement(1182..1808)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525297.1"
                     /locus_tag="BG16_RS09455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5580"
                     /product="LysE family translocator"
                     /protein_id="WP_004528842.1"
                     /transl_table=11
                     /translation="MFSAHLLLVYVAAVVAVYAVPGPDMAFVLQTGIGRGARHGAAAAA
                     GLGLARAVHVTLSACGVAALLKSAPWLYEAVRYGGALYLAYVAVQIFRSPAFALSAADA
                     AAPAARLRHTFVKGLLTNLLNPKALLFCSVLLPQFVQRGGAPVIAQMAVLGAVLVLAGL
                     CFDLACVAGATRIAEWLRAHPLAQLAQRWTFSAVLLGFALRLSID"
     misc_feature    1912..1923
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.57"
                     /tool="antismash"
     gene            1942..2406
                     /locus_tag="BG16_RS09460"
                     /old_locus_tag="BG16_5581"
     CDS             1942..2406
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188527.1"
                     /locus_tag="BG16_RS09460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5581"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_004188527.1"
                     /transl_table=11
                     /translation="MIELDKTDRAILAAVQLDGRIPVARLADSVGLSETPCARRLKRLE
                     SDGYIERYRAQLSRNALGFGVVAFVLLRCSVHDRSVANRFEREVLGIPRILSCHNVSGS
                     ADYLLQVVAHDLDDYGTFLRETLRVLPGVTSIESALSLREVKREAELPIP"
     gene            2755..3159
                     /locus_tag="BG16_RS09465"
                     /old_locus_tag="BG16_5582"
     CDS             2755..3159
                     /NRPS_PKS="Domain: Polyketide_cyc2 (10-121). E-value:
                     2.8e-14. Score: 45.7. Matches aSDomain:
                     nrpspksdomains_BG16_RS09465_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009934737.1"
                     /locus_tag="BG16_RS09465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5582"
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_004528843.1"
                     /transl_table=11
                     /translation="MTEAEPIRLEQFVARPPAQVWAALTTPAALARWWAAGDVRPVPGH
                     RFTLDMGPWGRQPCEVIAVEPERRFAIAFAQRTLDTTITWRLEPAPGGTRVCFEHAGFD
                     LDAPQARIAYDGMKRGWPSVLARIEQAIDG"
     aSDomain        2785..3117
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG16_RS09465_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.80E-14"
                     /label="BG16_RS09465_Polyketide_cyc2.1"
                     /locus_tag="BG16_RS09465"
                     /protein_end="121"
                     /protein_start="10"
                     /score="45.7"
                     /tool="antismash"
                     /translation="QFVARPPAQVWAALTTPAALARWWAAGDVRPVPGHRFTLDMGPWG
                     RQPCEVIAVEPERRFAIAFAQRTLDTTITWRLEPAPGGTRVCFEHAGFDLDAPQARIAY
                     DGMKRGW"
     misc_feature    3468..3482
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.41"
                     /tool="antismash"
     gene            3496..5082
                     /locus_tag="BG16_RS09470"
                     /old_locus_tag="BG16_5583"
     CDS             3496..5082
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188605.1"
                     /locus_tag="BG16_RS09470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5583"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_004188605.1"
                     /transl_table=11
                     /translation="MNPLLSAAASEELGRTRHLGVALLVALLAAGVAYVFVHLFADLAP
                     VGPRSAFPYLLLGVALAIALGFEFVNGFHDTANAVATVIYTHSLTPNVAVIWSGLWNFL
                     GVMASTGAVAFGILQLLPVELILQVGHGAGFAMVFALLIAAIAWNLATWYFGLPSSSSH
                     TLIGSIIGVGLANQLMHGPSGTSGVDWAQAAGVGQSLLLSPLVGFLCAALLLAALKALV
                     RVPALYREPQTNEPPPFWVRCLLILTCTGVSFAHGSNDGQKGMGLIMLILIGTVPTAYA
                     LNKAVTPGETQTFIAVAHRASETLARYAGAAQPSPNPRADVEAYVQSRRLSDATLPAVR
                     RLSDALAAEVGATGSIAKVPEGQADNVRNTMYLVSEALRLMEKTGRPAFSPADRLALDD
                     YRRQLDHATKFIPTWVKVAVAIALGLGTMVGWRRIVVTVGEKIGKQHLTYGQGASAEVV
                     AMLTIGAADAYGLPVSTTHVLSSGVAGTMAANGSGLQWSTVRSLVLAWVLTLPASIVLA
                     GALYWAFHALT"
     gene            5232..6014
                     /locus_tag="BG16_RS09475"
                     /old_locus_tag="BG16_5584"
     CDS             5232..6014
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188398.1"
                     /locus_tag="BG16_RS09475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5584"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_038739723.1"
                     /transl_table=11
                     /translation="MNTLSEPRVPAARAHDETASGAAREAALARRIDALPWASIERDLE
                     RDGHAIVHGLLAPRTCEALAALYARDALFRSRVTMARHGFGRGEYQYFGYPLPRAVHAL
                     RTALYPHLAPIANRWHAQMRIDARFPAEHAHFIARCRAAGQLRPTPLLLRYREGDYNCL
                     HQDLYGEHVFPLQAAVLLSKPGADFAGGEFVITEQRPRMQSRADVVPLEQGDAVVFAVH
                     HRPVQGARGVYRVNLRHGVSRVRSGQRHTLGIIFHDAP"
     misc_feature    complement(5234..5245)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.02"
                     /tool="antismash"
     misc_feature    6349..6369
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.65"
                     /tool="antismash"
     gene            6610..8217
                     /locus_tag="BG16_RS09480"
                     /old_locus_tag="BG16_5585"
     CDS             6610..8217
                     /NRPS_PKS="Domain: AMP-binding (8-434). E-value: 6.8e-92.
                     Score: 300.1. Matches aSDomain:
                     nrpspksdomains_BG16_RS09480_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004551903.1"
                     /locus_tag="BG16_RS09480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5585"
                     /product="acyl-CoA ligase (AMP-forming), exosortase A
                     system-associated"
                     /protein_id="WP_004551903.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-94, bitscore:
                     314.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNFFDLVEQAACRTPDAEALVAGDARLTYRALAALGLAFAERLQ
                     ALEIAQGERLAIFLDKRIETVVAMLGAAAAGVVFVPINPALKPEQVHHILVDSGARCLV
                     TSSLRARILGDGVLAGMPYVILTDAKTLAPAPASRTTFLRWMQPDAPPESVANRHASAA
                     PEPRADTIDADLAALLYTSGSTGRPKGVMLSHRNLLEGAWSVAQYLRHTAQDRILAALP
                     LSFDAGLSQLTTAWAAGASAVLVNYLMPADVVEICVRERITGFAGVPPLWIQLARAAWP
                     GEARARLRYFANTGGHLPRPVLHALRELFPSASPYLMYGLTEAFRSTYLDPAEVDRRPD
                     SIGKAVPNARILVVREDGAPCAPNEVGELVHVGACVTLGYWNDPARTALRYRPSPEAKP
                     GGAPRETAVWSGDLVRRDDDGFLYFVARNDAQIKSSGYRISPEEIEEVAHASGLVAEAV
                     ALGVPHDELGESITLVVVPLDADTFRPDALRARCAQQLPPYMVPHTIATRTSLPRNPNG
                     KFDRVALRADAANLVETL"
     aSDomain        6634..7911
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG16_RS09480_AMP-binding.1"
                     /evalue="6.80E-92"
                     /label="BG16_RS09480_AMP-binding.1"
                     /locus_tag="BG16_RS09480"
                     /protein_end="434"
                     /protein_start="8"
                     /score="300.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EQAACRTPDAEALVAGDARLTYRALAALGLAFAERLQALEIAQGE
                     RLAIFLDKRIETVVAMLGAAAAGVVFVPINPALKPEQVHHILVDSGARCLVTSSLRARI
                     LGDGVLAGMPYVILTDAKTLAPAPASRTTFLRWMQPDAPPESVANRHASAAPEPRADTI
                     DADLAALLYTSGSTGRPKGVMLSHRNLLEGAWSVAQYLRHTAQDRILAALPLSFDAGLS
                     QLTTAWAAGASAVLVNYLMPADVVEICVRERITGFAGVPPLWIQLARAAWPGEARARLR
                     YFANTGGHLPRPVLHALRELFPSASPYLMYGLTEAFRSTYLDPAEVDRRPDSIGKAVPN
                     ARILVVREDGAPCAPNEVGELVHVGACVTLGYWNDPARTALRYRPSPEAKPGGAPRETA
                     VWSGDLVRRDDDGFLYFVARNDAQIKS"
     CDS_motif       7135..7194
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS09480_0001"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BG16_RS09480"
                     /protein_end="195"
                     /protein_start="175"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AALLYTSGSTGRPKGVMLSH"
     CDS_motif       7696..7779
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS09480_0002"
                     /evalue="7.90E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="BG16_RS09480"
                     /protein_end="390"
                     /protein_start="362"
                     /score="27.8"
                     /tool="antismash"
                     /translation="PNEVGELVHVGACVTLGYWNDPARTALR"
     CDS_motif       7879..7944
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG16_RS09480_0003"
                     /evalue="8.30E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="BG16_RS09480"
                     /protein_end="445"
                     /protein_start="423"
                     /score="21.5"
                     /tool="antismash"
                     /translation="FVARNDAQIKSSGYRISPEEIE"
     gene            complement(8575..8811)
                     /locus_tag="BG16_RS35335"
     CDS             complement(8575..8811)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525293.1"
                     /locus_tag="BG16_RS35335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_080340880.1"
                     /transl_table=11
                     /translation="MTLKLSANNIKCNNDCKSGVRIIEIHLTMAFDIFIPALRVFFAVC
                     NDPIGKAAGRGQIDTAIGILNRCCDAIGKFISF"
     misc_feature    complement(8617..8619)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8778..8794)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.71"
                     /tool="antismash"
     misc_feature    8784..8793
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.85"
                     /tool="antismash"
     misc_feature    8787..8801
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.94"
                     /tool="antismash"
     misc_feature    complement(8893..8907)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    8918..8933
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.3"
                     /tool="antismash"
     gene            8985..9677
                     /gene="bpsR3"
                     /locus_tag="BG16_RS09485"
                     /old_locus_tag="BG16_5586"
     CDS             8985..9677
                     /codon_start=1
                     /gene="bpsR3"
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188690.1"
                     /locus_tag="BG16_RS09485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5586"
                     /product="N-acyl-homoserine lactone dependent regulator
                     BpsR3"
                     /protein_id="WP_004188690.1"
                     /transl_table=11
                     /translation="MLSAALPESRDVRTLVETFRQAALQIGYQHHAIVELSGASHPASI
                     DVVSLHYPSEWVEHYTRNDYFAIDPVHRAAFRYSTPFSWNDVATANLRERHLLMEAEDA
                     GLDNGISIPLHQPLGRVLLVSLSGTAPTHDADAKWRNAYLLGMQFNLQFQSMRTCRPIP
                     PSVHLTDREQMCLTWVARGKSSWVIANMLDISKYTVDFHIENAMEKLNTRSRTFAAVKA
                     TRQGLIFP"
     misc_feature    complement(9956..9965)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            10001..10609
                     /gene="bspI3"
                     /locus_tag="BG16_RS09490"
                     /old_locus_tag="BG16_5587"
     CDS             10001..10609
                     /codon_start=1
                     /gene="bspI3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004528852.1"
                     /locus_tag="BG16_RS09490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5587"
                     /product="N-acylhomoserine lactone synthase BspI3"
                     /protein_id="WP_004528852.1"
                     /sec_met_domain="Autoind_synth (E-value: 1e-23, bitscore:
                     81.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYIIAGRLNELPPHVQTDLGAYRYDVFVRRLGWTIAGHSLDEHA
                     EWDEFDGPSTIHVVALDDAREICGYARLLPTTGPYLLRDVFAHLLGSSPAPQSPAVWEM
                     SRFAASRRRRSATEREPLGMAFFPSVLTVAASLGATRVVGVMTPSIERLYRRSGIALHR
                     LGNAMPGAGGSLSACSIDLPRLAFAPLGRKQCAACLAMH"
     misc_feature    10897..10913
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            10951..12276
                     /locus_tag="BG16_RS09495"
                     /old_locus_tag="BG16_5588"
     CDS             10951..12276
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004555031.1"
                     /locus_tag="BG16_RS09495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5588"
                     /product="NADH:flavin oxidoreductase/NADH oxidase family
                     protein"
                     /protein_id="WP_004528855.1"
                     /transl_table=11
                     /translation="MPDSNPTAAALLAQPLTLPNGTVLKNRLAKSALSEALCGHDGRVT
                     PQLIALYRRWSGSGAGLLVTGNVMIDGKALGEPGNVVIEDDRDLPRLREWAAAAKAHGS
                     EIWMQINHPGKQAMRGLNEETVAPSAIGFGPKLSPYFAVPRALTVDEIDALIRRYGTTA
                     AVAQQAGFTGVQLHGAHGYLINQFLSPQHNQRTDEWGGSAENRRRFVLAVYAEVRRRVG
                     PDFPIGIKLNSADFQRGGFTEEESLDVIRALAEAGIDLIEISGGTYETPVMQLGDRKAS
                     TIAREAYFLAFAEKVRADVKVPLMVTGGFRSLAGMEAPLRDGALDLIGLGRILAIEPDA
                     PARLLRGEETRHRVKPLSTGVKYFDSLGSLEVTWYTRQLHRIGKGRNPIPDENALKSFL
                     LDLSSKGCAIFKARRLRASSSEASAARGSATSVAGGPRHDAH"
     gene            complement(12622..13473)
                     /locus_tag="BG16_RS09500"
                     /old_locus_tag="BG16_5589"
     CDS             complement(12622..13473)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011853486.1"
                     /locus_tag="BG16_RS09500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5589"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_004528857.1"
                     /transl_table=11
                     /translation="MAATEPNADLALPLPATHAAASAAARRAPRVHAGHAAALATWVAL
                     AAGWWLAARFEWVSAALLPGPEAVLRKLVVLSTEGFDDATLGEHLLASVSRIATAFALA
                     IVTAIPVGILVATNRIVRGVVDPIVEFYRPIPPLAYLPLMVVWFGIGDASKILLIYLTM
                     FAPLAIATAAGASGVSESRLRAAASLGATRVQLLRHVVLPSALPDILTGVRIALGAGWS
                     TLVAAELIAATRGLGFMVYSASRFLVTDVVIAGILVIGAIALALEIGLRALQRRLTPWR
                     AD"
     gene            complement(13476..14258)
                     /locus_tag="BG16_RS09505"
                     /old_locus_tag="BG16_5590"
     CDS             complement(13476..14258)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006028946.1"
                     /locus_tag="BG16_RS09505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5590"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_004188097.1"
                     /transl_table=11
                     /translation="MAKLCAQQVSVVYASRRGALTALENVSMSVGSGEIVVALGASGCG
                     KSTLLSLLAGFQPPTSGRVSVDGAPVAGPGADRGVVFQDDALMPWLNVIENVAFGLRMQ
                     GVGRDARHARARDVLRLVKLAGFEQHRIDEISGGMRQRVGLARALAADPSFLLMDEPLG
                     ALDALTREHMQTLLLDVWRATGKGVFLITHSVEEAVLLATELLILSPRPGRIVARHSLD
                     FARRYAHGEPMRSIKSDPRFTEIHLALVEQLMRETEEV"
     gene            complement(14279..15289)
                     /gene="tauA"
                     /locus_tag="BG16_RS09510"
                     /old_locus_tag="BG16_5591"
     CDS             complement(14279..15289)
                     /GO_component="GO:0009897 - external side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015411 - ABC-type taurine transporter
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0030977 - taurine binding [Evidence IEA]"
                     /GO_process="GO:0015734 - taurine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tauA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525289.1"
                     /locus_tag="BG16_RS09510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5591"
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_004525289.1"
                     /transl_table=11
                     /translation="MILKRILIAASFTAAAASAVHSHAARAETVNVAYQYGADPAKLAQ
                     AGAAYEKATGWKINWRRFDSGADVVAALASGDVQLGDVGQSPFTAAVSRGVPIQAVALN
                     AITGVSEALVVRRGAHIDKPADLVGKTIATPYASNCHYALLAALKHWGIDAQRVKIVNL
                     GPTEIVAAWARGVIDAAYTWDPALGRAKASGGKVLVDSAEVGKWGAPTFDLWAVRSDFA
                     QAHPDFVSKFVKVTTQAIADYRANGKAWTSASRQVAEISRLSGAAAGDIAQLLAGNLYP
                     SAAEQASPELLGGGTADAIASTARFLKEQRKIDRVLPDYRPTVTDRFVRAAIAAR"
     misc_feature    15278..15293
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.08"
                     /tool="antismash"
     misc_feature    15477..15489
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.62"
                     /tool="antismash"
     gene            15592..16425
                     /gene="tauD"
                     /locus_tag="BG16_RS09515"
                     /old_locus_tag="BG16_5592"
     CDS             15592..16425
                     /EC_number="1.14.11.17"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (6-270). E-value: 5.1e-68. Score:
                     221.7. Matches aSDomain:
                     nrpspksdomains_BG16_RS09515_TauD.1"
                     /codon_start=1
                     /gene="tauD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004530602.1"
                     /locus_tag="BG16_RS09515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5592"
                     /product="taurine dioxygenase"
                     /protein_id="WP_038727472.1"
                     /sec_met_domain="TauD (E-value: 2.3e-66, bitscore: 221.7,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRLTLTRLTPALGAIVDDVDLSNATDALRDDIRVALAHHQVLFF
                     RGQRLSAARHRDFAAGFGDLHVHPIYPPHPDAREIMVLDNAVFDLQDNAIWHTDVTFTE
                     TPPRASILAAHTLPETGGDTLWGSGFAAYDALSGRVKAQLDGLTAQHDFTKSFPLKRFG
                     VTAEDRARWEKTRATHPSVAHPVVRTHPETGRKTLFVNEGFTTEIDGLPEEEGAALLRF
                     LFAHQSRPEFTLRWRWQPGDVAFWDNRSTIHYAVNDYGKAHRVMHRATIVGDRPY"
     aSDomain        15610..16401
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG16_RS09515_TauD.1"
                     /evalue="5.10E-68"
                     /label="BG16_RS09515_TauD.1"
                     /locus_tag="BG16_RS09515"
                     /protein_end="270"
                     /protein_start="6"
                     /score="221.7"
                     /tool="antismash"
                     /translation="TRLTPALGAIVDDVDLSNATDALRDDIRVALAHHQVLFFRGQRLS
                     AARHRDFAAGFGDLHVHPIYPPHPDAREIMVLDNAVFDLQDNAIWHTDVTFTETPPRAS
                     ILAAHTLPETGGDTLWGSGFAAYDALSGRVKAQLDGLTAQHDFTKSFPLKRFGVTAEDR
                     ARWEKTRATHPSVAHPVVRTHPETGRKTLFVNEGFTTEIDGLPEEEGAALLRFLFAHQS
                     RPEFTLRWRWQPGDVAFWDNRSTIHYAVNDYGKAHRVMHRAT"
     gene            complement(16691..16885)
                     /locus_tag="BG16_RS09520"
                     /old_locus_tag="BG16_5593"
     CDS             complement(16691..16885)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009977638.1"
                     /locus_tag="BG16_RS09520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5593"
                     /product="hypothetical protein"
                     /protein_id="WP_004528860.1"
                     /transl_table=11
                     /translation="MTNGNRNTPAARGDAPPPAHDIAGLARHVREIDPARYLDEQARLA
                     YRTALKRWPVLAKLMGLAD"
     gene            complement(16882..18438)
                     /gene="bcsG"
                     /locus_tag="BG16_RS09525"
                     /old_locus_tag="BG16_5594"
     CDS             complement(16882..18438)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030244 - cellulose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="bcsG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004549777.1"
                     /locus_tag="BG16_RS09525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_5594"
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="WP_004525287.1"
                     /transl_table=11
                     /translation="MTFWNLYFILKLYLFAAGHLKPLWIANLGFALALALSAPARRRGV
                     RLLRHALALALAVPLMYREADVPPLARLVETLGGLRAFSAGYWMELVPRFVPPMLALAA
                     LGVVIGYLIVNRWLRVATFVLLALIALPVWQAGSAALARLDAAAAAVPGPAGTGRAVQP
                     QDHNAALAAFRSQESQRQVTFGRPSADPATQFDVIVLHVCSLSWDDLDVARLRNHPLLG
                     HFDYLFTNFSTAASYSGPAAIRVLRASCGQEAHADLYKPAPAQCHLFGQLAAAGFAPQT
                     LLNHDGHFDNFLQLIRENIGVPNAPMIPNADAPVAMHAFDGSAIKDDYATLANWYAKRG
                     ASPGPVALYYNTISLHDGNQLTGGRMSSLDSYPLRARKLLDDFDRFADLIAASGRRAVI
                     VFVPEHGAALRGDAKQVAGLREIPTPRIVHGPVGVRLVGFKGDHGATTVIDAPASFLAL
                     AQLLANLVSNSPFKPGVTLSQYAADLPQTRMIGENEGTVTMTTPTGYAVKTPDGVWIDE
                     K"
     misc_feature    complement(18408..18422)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.19"
                     /tool="antismash"
     misc_feature    19007..19021
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    complement(19157..19167)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.16"
                     /tool="antismash"
     misc_feature    20368..20382
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.65"
                     /tool="antismash"
ORIGIN
        1 cgacttcgcc gtccggcccg ctcggatcgc ccgtcggcgc gttgcgcccc gcgccgacgc
       61 tcacgtcgac gagcttcggc tgccgcgcga gcccgaggcc gccgaaatac tgctggatct
      121 cggccggccg atagccgccg ccgagctcga cgatcgcgat gcactggccc gcgccgtcgc
      181 cgggcgggaa atcgtagagg gccgcgagct gcggcggcgt gtaggtgacg gccggcgcgc
      241 gcgcgggcag gaaagtcggc cgcagccgga aatgcggccg ggcctgcggg cgatcgtcga
      301 gcccgagcac cgcggtgacg atgccgtgca actcgtcggg cagcgtgata tcgcccgtgc
      361 ggccgcgata ctggccgatc gaccgatgct cgaagcgctc gagcttcacg ccgaaggccg
      421 cctcgaactg cgcgatcgtg cccgacagca cgacgaggct ctcgaccgga tcgacgcgcg
      481 cgaccgcgag gccgcgctgc tgcgcgaatg cctcgacttt catgacgtcg tcgggatgcg
      541 cgccgaaacg ctgggcgaac gcctcgcgcg agacaggctt cacgcccgga tcgccgctcg
      601 cgaggccctg caacaatgaa tcgaggtgct gctcttgctg tcgccgcaac atcaccacta
      661 catgaatcgt ctcggccgga tcgcacggcc cgatgcacgt ggattcggcg acgagatgcg
      721 attcgttgcc ggcgtgaaga tgccttgcca tattcggacc ctccagaagc cgtggtgacg
      781 gattgccagg attcggacac ggtcgcgcga tcgcagttcc gggcggtatg tcggacggcg
      841 cacacacgcc gccatgggga gcgtgcgaca gtacggcaaa gcaagtgtaa agcacgcgcg
      901 gcaatcctgc gtgcgcatct cgcgcgtttg cgccgcccgt tcgcgacgtt cggcgcgccg
      961 cgcgagatcg ggcatgcgca cctgccggcg cgcgcgacgc gcatgcgacg catgcagcgc
     1021 gccgcgtcga cgcgatcgcg ggcgatggcg cgcgtttcgc gattggttgc cgattggttg
     1081 cctcgcgtgc cccgcgattc gccccgcgcg ccgcgcttcg ccgccgcccg cgctcgtgcg
     1141 cgccgcatcc gccgaccggg gcggtccggg gtcgatcgga atcagtcgat cgacagccgc
     1201 agcgcgaagc cgagcagcac ggcggaaaac gtccagcgct gggcgagttg cgcaagcgga
     1261 tgcgcgcgca accattcggc gatgcgcgtc gcgccggcga cgcacgcgag atcgaagcac
     1321 aggcccgcga gcacgagcac cgcgccgagc accgccatct gcgcgatcac cggcgcgccg
     1381 ccccgctgga cgaactgcgg cagcagcacc gagcagaaca gcagcgcctt cgggttgagc
     1441 agattggtga ggaggccctt gacgaaggta tggcgcagcc gggcggcggg cgcggccgcg
     1501 tcggcggcgg acagcgcgaa cgccggcgag cggaagatct gcaccgcgac gtacgcgagg
     1561 tacagcgcgc cgccgtagcg cacggcctcg tagagccacg gcgcgctctt caggagcgcg
     1621 gcgacgccgc atgcggacaa cgtcacgtgc acggcgcgcg cgagcccgag ccccgcggcg
     1681 gcggccgcgc cgtgccgcgc gccgcggccg atgcccgtct gcagcacgaa cgccatgtcg
     1741 gggccgggca cggcatagac ggccacgacg gcggcgacgt agacgagcag cagatgagcg
     1801 gaaaacatga tcgaacccga gtggaaaggg ctccatgttg cacccgctcg acgagcgctt
     1861 tttggctaat ttggccgacc gatgcaccaa actgattgga atacactaat agaaaccgat
     1921 ttcttagagc tttcccacaa catgatcgaa ctcgacaaaa ccgaccgcgc cattctcgcc
     1981 gcagtgcagc tcgacggccg catcccggtc gcccgcctcg ccgattcggt gggcctgagc
     2041 gaaacgccgt gcgcgcgccg gctcaaacgc ctcgaaagcg acggctacat cgaacgctat
     2101 cgcgcgcagc tctcgcgcaa cgcgcttggc ttcggcgtcg tcgcgttcgt gctgctgcgc
     2161 tgctcggttc acgatcgcag cgtcgcgaac cgcttcgagc gcgaggtgct cggcattccg
     2221 cgcatcctgt cgtgccacaa cgtgtcgggg tccgccgact atctgctgca agtggtcgcg
     2281 cacgatctcg acgactacgg cacgttcctg cgcgagacgc tgcgcgtgct gcccggcgtc
     2341 acgtcgatcg aatcggcgct gtcgctgcgc gaggtgaaac gcgaggctga actgccgatt
     2401 ccgtgaacga cgccgcgaac ggctccgtcg ccgcatccgc ggctgcccat ggcgcgggtg
     2461 ggccggctgc ggccggccct gtgtcctccg cgtcctccgc gtccttcgcg tcctccgcgc
     2521 cctctgcgcc tgcgcgcctt cgcaccttcg caccttcgca ccttcgcacc ttcgcacctt
     2581 cgcaccttcg caccttcgca ccttcgcacc ttcgcacctt cgcaccttcg cgccttcgcg
     2641 cccccgcgcg tcccgcgctc cgcgggcagc gcgtcgcgcc gacgagccgt atcgtccggg
     2701 ggcggcatcc cctatcatgc gcattccgcc acgcgctttc tcgaatccga cgcgatgacc
     2761 gaagccgaac cgatccgcct cgagcaattc gtcgcccgcc cgcctgcgca ggtctgggcg
     2821 gcgctcacca cccccgcggc gctcgcgcgc tggtgggcgg cgggcgacgt acgccccgtc
     2881 cccggccacc gtttcacgct cgacatgggc ccgtggggcc ggcagccgtg cgaagtgatc
     2941 gcggtcgaac ccgaacgccg gttcgcgatc gcgttcgcgc aacgcacgct cgacacgacg
     3001 atcacatggc ggctcgagcc cgcgcccggc ggcacgcggg tgtgcttcga gcacgcgggc
     3061 ttcgatctcg acgcgccgca ggcgcgcatt gcctacgatg gaatgaagcg cggctggcct
     3121 tcggtgctcg cgcgcatcga gcaggcgatc gacggctgag cgcgcgccgc gcggccgccg
     3181 aaccggagcg ccgaattcgg gcgccgaatc gcggtctcga agcgcgccca gaccgtagcc
     3241 gcggagcgcg gtttcgcatc gcaattccga accgcggcca tgcatcgcag cgatgaatcg
     3301 cggcgccgaa ccgcgtggcc gagccgcgcg acagaattgc gcggcccaat cgcgtccccg
     3361 aatcccgcgc tcgcgatgcg cccatgaccg acgccccgag tcgcacaccc gaatcgcccc
     3421 ccctttgcgc gctgtcatca aactgcctga tcgcaagggc taggatcgaa cgatccgttc
     3481 caaacaaggg ccgtcatgaa tccccttctg tccgccgcgg cgagcgaaga gctcggtcgc
     3541 acccggcatc tgggcgtcgc gctgctcgtc gccctcctcg ccgccggcgt cgcgtacgtg
     3601 ttcgttcacc tgttcgcgga tctcgcgccc gtcggcccac gctcggcgtt tccgtatctg
     3661 ctgctcggcg tcgcgctcgc gatcgcgctc ggcttcgagt tcgtcaacgg cttccacgac
     3721 accgcgaacg ccgtggcgac cgtgatctac acgcattcgc tgacgccgaa cgtcgcggtc
     3781 atctggtcgg gcctctggaa ttttctcggc gtgatggcgt cgacgggcgc ggtcgcgttc
     3841 ggcatcctgc aactgctgcc cgtcgagctg atcctgcaag tcggccacgg cgcgggcttc
     3901 gcgatggtgt tcgcgctgct gatcgcggcg atcgcgtgga atctcgcgac ctggtacttc
     3961 ggcctgcctt cgtcgagctc gcacacgctg atcggctcga tcatcggcgt cgggctcgcg
     4021 aatcagctga tgcacgggcc gtccggcacg agcggcgtcg attgggcaca ggcggcgggc
     4081 gtcggccaat cgctgctgct ctcgccgctc gtcggcttcc tgtgcgcggc cctgctgctc
     4141 gccgcgctga aggcgctcgt gcgcgtgccc gcgctctacc gcgagccgca gacgaacgag
     4201 ccgccgccgt tctgggtccg ctgcctgctg atcctgacct gcaccggcgt gtcgttcgcg
     4261 cacggctcga acgacgggca gaaaggcatg gggctcatca tgctgatcct gatcggcacc
     4321 gtgccgaccg catacgcgct caacaaggcg gtcacgcccg gcgagacgca aacgttcatc
     4381 gccgtcgcac accgcgcgtc cgaaacgctc gcccgctacg cgggcgccgc gcagccgtcg
     4441 ccgaacccgc gcgccgatgt cgaggcttac gtgcagtcgc gccgcctgag cgacgcgacg
     4501 ctgcccgcgg ttcgccggtt gtcggacgcg ctcgcggccg aagtcggcgc gacgggctcg
     4561 atcgcgaaag tgcccgaggg gcaggcggac aacgtgcgca acacgatgta tctggtgtcc
     4621 gaagccctgc gcctgatgga gaaaaccggc cggccggcgt tctcgccggc ggatcgcctc
     4681 gcgctcgacg actaccgcag gcagctcgac cacgcgacca aattcattcc gacctgggtg
     4741 aaggtcgcgg tggcgatcgc gctcggcctc ggcacgatgg tcggctggcg gcgcatcgtc
     4801 gtgaccgtcg gcgagaagat cggcaagcag catctgacct atgggcaagg cgcgtcggcg
     4861 gaagtcgtcg cgatgctcac gatcggcgcg gccgatgcgt acgggctgcc ggtgtcgacg
     4921 acgcacgtgc tgtcttccgg cgtcgcgggc acgatggccg cgaacggctc cgggctgcaa
     4981 tggagcacgg tgcgcagcct cgtgctcgcg tgggtgttga cgctgcccgc gtcgatcgtg
     5041 ctcgcgggcg cgctctattg ggctttccac gcgctgacct gacgcgcatg gcggcgtgac
     5101 ggcccgcgcg cgagacatcg cgcgaaacat aatgcgcggc cgaattgcag cgcaagatcc
     5161 ggtgtgcatc gcttcgcccg ccccgctaga ctggccgcct cgatccccca cgatgccgcg
     5221 aggaagcgcc gatgaatacg ttgtccgaac cacgcgtgcc ggccgcccgc gcgcacgatg
     5281 aaacggcgag cggcgcggcg cgcgaagccg cgctcgcgcg gcggatcgac gcgttgccgt
     5341 gggcgtcgat cgaacgggat ctcgagcgcg acggccatgc gatcgtgcat gggctgctcg
     5401 cgccgcgcac gtgcgaagcg ctcgccgcgc tctacgcgcg cgacgcgctg ttccgcagtc
     5461 gcgtgacgat ggcacgccac gggttcggtc gcggcgaata ccagtatttc ggctacccgc
     5521 tgccgcgcgc ggtccacgcg ctgcgcaccg cgctgtaccc gcacctcgcg ccgatcgcga
     5581 accgctggca tgcgcagatg cgcatcgacg cgcggtttcc cgccgagcac gcgcacttca
     5641 tcgcgcgttg ccgcgcagcc ggacaactgc gtccgacacc gctgctgctg cgctatcgcg
     5701 aaggcgacta caactgcctg catcaggatc tgtatggcga gcacgtattc ccgctgcagg
     5761 cggcggttct gctgtcgaag ccgggcgccg atttcgcggg cggcgaattc gtgatcaccg
     5821 agcaacggcc gcgcatgcaa tcgcgcgccg atgtcgtgcc gctcgagcag ggcgacgcgg
     5881 tcgtgttcgc cgtccatcat cgcccggtgc aaggcgcgcg cggtgtctat cgcgtgaatc
     5941 ttcggcacgg cgtgagccgc gtgcgctccg ggcagcgcca tacgctcggg atcatcttcc
     6001 acgacgcgcc gtgacgccgg cgctcgcgct ggcgcgcgcg caccgcgcgc gcaccggcag
     6061 cccgccatcg gacgccgcgc cggccgacgc atgcgcacgc gcacgcacgc gtgcggcgca
     6121 cggccgccgg aacgaatcgc aatggttgcg cacacatcca ttcgccgcga agcgtgcatc
     6181 tcgcgcttcc atggaaagac gcggcgcgac accggttcct tgcaggcgat gcgagctcgc
     6241 ctcggcgcgt gccgctcgac atgcgatgcg ttcgcccgcg cgacacatgc aaccgaattg
     6301 aaagaccgtg tccgagcgcg ccggcgaaat tcatcaggac aattgacgat cacgtcgagc
     6361 agacgatctc ctccatgcgc gcgcgcgtgc atgtcgaatg tgctagcgcg gcgcgcggcc
     6421 gcatccgtca atgttcggca ccaccccgtt cggccattta catcgatgcg ccgcgaccgc
     6481 gcgccgtgtc cattcgctac tctttcggca gccaggatcg gccgcgttcg cgcgacggtc
     6541 gttagccatc gcgagcttcg ccgcatcgct cgacgtgcgc cgcccgagtt tcaaaacgga
     6601 ggtggaatca tgcgtaattt cttcgatctg gtcgaacagg cggcatgccg cacgcccgat
     6661 gccgaggcgc tcgtcgccgg cgacgctcgg ctcacctatc gcgcactcgc ggcgctcggc
     6721 ctggcgttcg ccgagcggct gcaagcgctc gagatcgccc agggcgagcg gctcgcgatc
     6781 tttctcgaca agcgcatcga gacggtcgtc gccatgctcg gcgccgcggc ggccggcgtc
     6841 gtgttcgtgc cgatcaaccc ggccctcaag cccgaacagg ttcatcacat cctcgtcgac
     6901 agcggcgcgc gctgtctcgt cacgtcgtcg ctgcgcgcgc gcatactcgg cgacggcgtg
     6961 ctcgcgggca tgccgtacgt gatcctgacc gatgcgaaga cgcttgcacc ggcgccggct
     7021 tcgcgcacca cgtttctgcg atggatgcag cccgatgcgc cgcccgagtc cgtcgcgaac
     7081 cggcacgcga gcgccgcgcc cgagccgcga gcggacacga tcgacgccga tctcgccgca
     7141 ctcctttaca cgtccggctc gacgggccgc cccaagggcg tgatgctcag ccaccgcaat
     7201 ctgctcgagg gcgcgtggag cgtcgcgcaa tacctgcgcc ataccgcgca ggatcgcatt
     7261 ctcgccgcgc tgccgctcag cttcgacgcc ggcttgagcc agttgacgac cgcatgggcc
     7321 gcgggcgcga gcgccgtgct cgtcaactac ctgatgcccg cggacgtcgt cgagatctgc
     7381 gtgcgcgaac gcatcaccgg cttcgcgggc gtaccgccgc tctggattca gctcgcgcgc
     7441 gcggcgtggc ccggcgaagc gcgcgcgcgg ctgcgctatt tcgcgaacac cggcggccat
     7501 ctgccgcggc cggtgctgca cgcgctgcgc gaactgtttc cgagcgcgtc gccgtatctg
     7561 atgtacgggc tgaccgaagc gttccgctcg acctacctcg atcccgccga agtcgaccgt
     7621 cgccccgatt cgatcggcaa ggcggtgccg aacgccagaa ttctcgtcgt gcgcgaggac
     7681 ggcgcgccgt gcgcaccgaa cgaggtcggc gagctggtcc acgtcggcgc gtgcgtgacg
     7741 ctcggctact ggaacgatcc ggcgcgcacc gcgctgcgct accggccttc gcccgaggcg
     7801 aagccgggcg gcgcgccacg tgagacggcc gtctggtccg gtgatctcgt gcgccgcgac
     7861 gacgacggat tcctctattt cgtcgcccgc aacgatgcgc agatcaagag ttccggctac
     7921 cggatcagcc cggaagagat cgaggaggtc gcgcacgcga gcgggctcgt ggccgaagcg
     7981 gtcgcgctcg gcgtgccgca cgacgaactc ggcgaatcga tcacgctcgt cgtcgtgccg
     8041 ctcgacgccg acacgttcag gcccgacgcg ctgcgcgcgc gatgcgcaca gcaacttccc
     8101 ccgtacatgg tgccgcatac gatcgccacg cgcacgtcgc tgccgcgcaa tccgaacggg
     8161 aaattcgatc gcgtcgcgct gcgcgccgac gcggcgaacc tcgtcgaaac gctctgaaga
     8221 cgcgccggat cgccgcgcga gacgctcgtc tacgcgcgac gtccgccgcc cgcctccgtt
     8281 gcctacgccg tacccggcgc cccgggcggc gcgacgttgc gaacgcgcgc gctggggcac
     8341 cgcggcagcg ggcgccgccg cgcgcgccgc ttcgggccga gccgcggcag gcgccggctc
     8401 gcgttccgcc acgaatatat tcgcgcgccg tttctcgacg aaaaacaaga atttaccgca
     8461 catctaataa gacggaatcc ggcggaataa tcattcgaca ccatcctcgg ctgacagcga
     8521 tttcgcatga agattcggca cttactcgcg atccgcgcaa aagattggct cactctaaaa
     8581 tgaaatgaac ttacctattg catcgcagca tcggtttaaa ataccgattg ccgtatcgat
     8641 ctgtccacgc cctgccgcct tgccgatcgg atcgttgcag acagcgaaaa atacccgaag
     8701 cgccgggata aaaatatcga acgccatcgt caaatgaatc tcgattatcc gaacgccgct
     8761 cttgcaatcg ttattgcatt tgatattatt tgcagacaat ttcaacgtca ttgcgttatc
     8821 cgattttcat tggcgacgcg tccccaaccc ggtacacggc acttcgaaag tcttgatttt
     8881 caataacggg ggcatgcaaa ttgagcaggc tgcttcaacg cgaatatcga acaggtggag
     8941 atgacggtgc ggggtcgtcg tcgggagaaa gcgcttcgac acccatgctc tccgccgcgt
     9001 tgccggaatc gcgcgacgtc cgcacgctgg tcgagacttt ccggcaggcg gcgctgcaga
     9061 tcggctacca gcaccatgcg atcgtcgagc tgtcgggcgc atcgcatccg gcgtcgatcg
     9121 acgtcgtctc gctgcactat ccgtccgagt gggtcgagca ctacacccgc aacgactact
     9181 tcgcgatcga tcccgtccat cgcgcggcat tccgctacag cacgccgttc tcgtggaacg
     9241 acgtcgcgac ggcgaacctg cgcgagcggc atctgctgat ggaagccgag gacgcgggcc
     9301 tcgacaacgg catcagcatc ccgctgcatc agccgctcgg acgcgtgctg ctggtgagcc
     9361 tgtccggcac cgcgccgacg cacgatgccg atgcgaaatg gcgcaacgcg tacctgctcg
     9421 gcatgcagtt caatctgcag ttccagagca tgcgcacgtg ccgcccgatt ccgccgtccg
     9481 tccacctgac ggatcgcgaa cagatgtgcc tcacgtgggt cgcgcgcggc aagtcgtcgt
     9541 gggtcatcgc gaacatgctc gacatctcca aatacacggt cgacttccac atcgagaacg
     9601 cgatggagaa gctcaacacg cgcagccgca cgttcgccgc cgtgaaggcg acgcggcagg
     9661 ggctcatctt tccatgagcg cgcgatccat ccggatccgt tagcgccgcc cgtttcatcc
     9721 gccaccgcgc gccgacgcga tgcaaccggc cgcttgcatc ggactgccga tcgatgccgc
     9781 gccggcctgc gcgccgaacg ccgccgcccg ccctcgtcgc gcctcgcggc gaggccgcgc
     9841 cgcgcgcgcg cattgccgta tcgccgtatc gccgcgcctt cgtgtcgcgc aacagccttc
     9901 gagaccgcgc acgcgtgctt ctcgaccctc accgctcata cgcgatcgga acgcgcgccg
     9961 ccttcgcgcc gacgatcgat ccatcggaga accaagcgcc atgtcataca tcatcgcggg
    10021 ccgattgaac gaactgccgc cgcacgtcca gaccgatctc ggcgcgtatc gctacgacgt
    10081 gttcgtgcgc cggctcggct ggacgatcgc cggccactcg ctcgacgaac atgcggagtg
    10141 ggacgagttc gacgggccgt cgacgattca tgtcgtcgcg ctcgacgacg cgcgcgagat
    10201 ctgcggctac gcacgcctgc tgccgacgac gggcccgtat ctgctgcgcg acgtgtttgc
    10261 gcatctgctc ggctcgtcgc ccgcgccgca atcgcctgcc gtctgggaaa tgtcgcgctt
    10321 cgccgcgtcg cggcggcggc gaagcgcgac cgagcgcgag ccgctcggca tggcgttctt
    10381 tccgtcggtg ctcacggtgg ccgcgtcgct cggcgcgacg cgcgtggtcg gcgtgatgac
    10441 gccatcgatc gaacgcctgt accgccgctc gggcatcgcg ctgcatcgcc tcggcaacgc
    10501 gatgccgggc gcgggcggca gcctgtccgc atgctcgatc gatctgccgc gcctcgcgtt
    10561 cgcgccgttg ggccgcaagc agtgcgcggc gtgcctggcg atgcattgac caggaaggcg
    10621 ggcgcatcgg gcgagacacg cgtcttgtcg tttttgccga tgtcgacgcg ctcgcctgac
    10681 gccatcgccc ggtgcgtcgc gacgccgcgc gccgccgaat tggacgttct cctctaaccg
    10741 gaccgccaac gcgccgccgg gcggcgggcc gccacggacg cgggccaccg cccgtcgccc
    10801 cgctcgcccg ccccggcacg cccatcgccg tgcgggtcgc tccgtcttga ctcagttccg
    10861 attttgaact tacgatccca accaatacat caatcgatgt aacattactc gatggatttt
    10921 cggtcgtcga cccaaccgga gcgtcatgcc atgcccgatt cgaatcccac cgcggccgcg
    10981 ttgctcgcgc agccgctcac gctgccgaac ggcaccgtgc tgaagaaccg cctcgcgaaa
    11041 tcggcgctga gcgaagcgct gtgcgggcac gacggccgtg tgacgccgca gctgatcgcg
    11101 ctgtaccggc gctggtcggg ttcgggcgcg gggctgctcg tcaccggcaa cgtgatgatc
    11161 gacggcaagg cgctcggcga gcccggcaac gtcgtgatcg aggacgaccg cgatctgccg
    11221 cgtctgcgcg aatgggccgc ggccgcgaaa gcgcacggca gcgagatctg gatgcagatc
    11281 aatcatcccg gcaagcaggc gatgcgcgga ctcaacgagg aaaccgtcgc gccgtcggcg
    11341 atcggcttcg ggccgaagct ttcgccgtat ttcgcggtgc cgcgcgcgct aaccgtggac
    11401 gagatcgacg cgctgatccg gcgctacgga acgacggccg ccgtcgcgca gcaggcgggc
    11461 ttcaccggcg tgcagttgca cggcgcgcac ggctatctga tcaaccagtt cctgtcgccg
    11521 cagcacaatc agcgcaccga cgaatggggc ggcagcgcgg agaaccgccg gcgcttcgtg
    11581 ctcgcggtgt acgcggaagt gcggcgccgg gtgggccccg attttccgat cggcatcaag
    11641 ctcaattcgg ccgatttcca gcgcggcggc ttcaccgagg aagaatcgct cgacgtgatc
    11701 cgcgcgctcg ccgaggcggg catcgatctg atcgagattt ccggcggcac ctacgaaacg
    11761 cccgtgatgc agctcggcga ccgcaaggcg tcgacgatcg cgcgcgaagc gtacttcctc
    11821 gcgttcgccg agaaggtgcg cgcggacgtg aaggtgccgt tgatggtcac gggcggcttt
    11881 cgcagcctcg ccggcatgga ggcaccgctg cgcgacggcg cgctcgacct gatcggcctc
    11941 gggcgtatcc tcgcgatcga gcccgacgcg cccgcgcgcc tgctgcgcgg cgaggaaacg
    12001 cgccatcgcg tgaagccgct cagcacgggc gtcaaatact tcgatagcct cggttcgctc
    12061 gaagtcacgt ggtatacgcg gcagctccat cgaatcggca aggggcgcaa tccgattccc
    12121 gacgagaatg cactgaaatc gttcctgctc gacctgtcgt ccaagggctg cgcgatcttc
    12181 aaggcgcgcc gcctgcgtgc ttcgtcctcc gaagcgtcgg ccgcgcgggg ttcggcgacg
    12241 tcggtcgccg gcggcccgcg gcacgatgcg cattgagcgg ggcgacccgc ctcgcgcaac
    12301 ggcgccgccc ggccgagtga acgccgcgcg gcgcgcggca tcggcgcatc gaatgcgctt
    12361 tgctcgatgc ttcgcgcgtt gaagccgcgg tggatagcca ggccgatgtc gatatcaact
    12421 tcgccgctca tcgctcatcg acgataaggg ataaggcgaa acgccgatga aacgaagcgg
    12481 cgcgcgcgtg atagcagatg aaccgccgca catcgtcacg gaccgccacg aaccggcgca
    12541 acgccggtgc gatctcggcg gcgccgatcg atcggccgcc ccccgcgccc ctgacgccca
    12601 ccgcatcgca aacgcgccgc gctaatcggc ccgccacggc gtcaatcgcc gctgcagcgc
    12661 gcgcaagccg atttccagcg cgagcgcgat cgcgccgatc acgaggatcc ccgcgatcac
    12721 gacgtccgtc acgaggaacc gtgacgcgga atacaccatg aagccgagcc cgcgcgtcgc
    12781 cgcgatcagc tccgccgcga cgagcgtcga ccatcccgcg ccgagcgcga tgcgcacgcc
    12841 ggtcaggatg tccggcagcg cgctcggcag cacgacgtgg cgcagcagtt gcacgcgcgt
    12901 cgcgccgagc gacgcggccg cgcgcaggcg gctttccgat acgccgctcg cgcccgcggc
    12961 ggtcgcgatc gcgagcggtg cgaacatcgt cagatagatc agcaggattt tcgacgcgtc
    13021 gccgatcccg aaccagacga ccatcaacgg cagatacgcg agcggcggaa tcggccggta
    13081 aaactcgacg atcggatcga cgacgccgcg cacgatccgg ttcgtcgcga ccaggatgcc
    13141 gaccgggatc gcggtgacga tcgcgagtgc gaacgccgtc gcgatccgcg acacgctcgc
    13201 gagcagatgt tcgccgagcg tcgcgtcgtc gaaaccctcg gtgctcagca cgacgagctt
    13261 gcgcagcacg gcctcggggc ccggcagcag cgcggccgat acccattcga agcgcgcggc
    13321 gagccaccag ccggcggcaa gcgcgaccca cgtcgcgagc gcggccgcgt ggcccgcatg
    13381 cacgcgcggc gcgcggcgcg ccgccgcgct cgcggccgca tgggttgccg gcagcggcag
    13441 cgcgagatcg gcattcggtt cagtggcggc caacgtcaaa cctcctcggt ttcgcgcatc
    13501 agctgctcga cgagcgcgag atggatttcg gtgaagcgcg gatcgctctt gatcgagcgc
    13561 atcggttcgc cgtgcgcgta gcgccgcgcg aagtcgagcg aatgccgcgc gacgatccgg
    13621 cccgggcgcg gcgacaggat cagcagctcg gtcgcgagca acaccgcttc ctcgacgctg
    13681 tgcgtgatca gaaacacgcc cttgcccgtc gcgcgccaca cgtcgagcag cagcgtctgc
    13741 atgtgctcgc gcgtgagcgc gtcgagcgcg ccgagcggct cgtccatcag caggaacgac
    13801 gggtccgcgg cgagcgcgcg cgcgagcccg acgcgctgcc gcatgccgcc cgaaatctcg
    13861 tcgatccgat gctgctcgaa gccggcgagc ttcacgagcc gcagcacgtc gcgcgcacgc
    13921 gcgtggcgtg cgtcgcggcc gacgccttgc atccgcagcc cgaacgcgac gttctcgatc
    13981 acgttcagcc acggcatcag cgcgtcgtcc tgaaacacga cgccgcgatc ggcgccgggc
    14041 cccgcgacgg gtgcgccgtc gacgctcacg cggcccgacg tcggcggctg aaagccggcg
    14101 agcagcgaca gcagcgtgct cttgccgcag ccggacgcgc cgagcgcgac aacgatctcg
    14161 ccgctgccga ccgacatcga tacgttctcg agcgccgtca gcgcgccgcg ccgcgacgcg
    14221 tagacgacgg atacctgttg cgcgcaaagc ttcgccatgc cgatgccgcc gcgtcgtctc
    14281 agcgcgcggc gatcgccgcg cggacgaacc ggtccgtcac cgtcggccgg taatcgggca
    14341 gcacgcggtc gatcttgcgc tgctccttca ggaagcgcgc ggtcgacgcg atcgcgtcgg
    14401 ccgtgccgcc gccgagcagc tcgggcgacg cctgctcggc cgcgctcggg tagagattgc
    14461 cggcgagcag ttgcgcaatg tcgcccgccg ccgcgccgct cagccgcgag atttcggcga
    14521 cctgccgcga cgcgctcgtc catgccttgc cgttcgcgcg atagtcggcg atcgcctgcg
    14581 tcgtcacctt cacgaacttc gacacgaaat ccggatgcgc ttgcgcgaaa tcgctgcgca
    14641 ccgcccacag atcgaatgtc ggcgcgcccc acttgccgac ttcggccgaa tcgacgagca
    14701 ccttgccgcc gctcgccttc gcgcggccga gcgccgggtc ccacgtatag gcggcgtcga
    14761 tcacgccgcg cgcccatgcg gcgacgatct cggtcggccc gagattcacg atcttcacgc
    14821 gctgcgcatc gatgccccag tgcttgagcg cggcgagcag cgcgtaatgg cagttcgacg
    14881 cgtaaggcgt cgcgatcgtc ttgccgacga gatcggccgg cttgtcgata tgcgcgccgc
    14941 ggcgcacgac gagcgcctcg gacacgccgg tgatcgcgtt cagcgcgacc gcctggatcg
    15001 gcacgccgcg cgacaccgcc gcggtaaacg gactctgccc gacatcgccg agctggacat
    15061 cgcccgaggc gagcgccgcg acgacatccg cgcccgaatc gaagcggcgc cagttgatct
    15121 tccagccggt ggccttctcg tacgcggcgc ccgcctgcgc gagcttcgcc ggatcggcgc
    15181 cgtactgata ggcgacgttc accgtctccg cccgggcggc gtgcgaatga acggccgagg
    15241 ccgcggcggc ggtgaaagac gcggcgatga ggatgcgctt gagaatcatg aacgggcctt
    15301 cccttctgct ggatgcgttg aattcggatg gccgtcgaga ttaccggctt gcgcgccgtc
    15361 cgttaaacaa cgaaatctgc gaaggatatg agacggcgca ttcggcgatg gcgccaagcc
    15421 ggccgcaatc ccggcgcgac gataagcaat gcggatttcg ttggttcacc aaacgaacgc
    15481 gttttgcgag acttggcggc ttcccgccat gcgaggcgca ctgaggcgca ctgaggcgca
    15541 ccgaggcgca ccgaggcgca ccgaggcgca ccgacgatat ccggaccgac gatgacccga
    15601 ctgacattga cccgactcac gcccgcgctc ggcgcgatcg tcgacgacgt ggacctctcg
    15661 aacgcgaccg acgccctgcg cgacgacatc cgcgtcgcgc tcgcgcacca tcaggtgctg
    15721 ttcttccgcg gccagcgcct gagcgcggcc cggcatcgcg acttcgcggc cggattcggc
    15781 gatctgcacg tgcacccgat ctatccgccg catccggacg cgcgcgagat catggtgctc
    15841 gacaacgccg tgttcgacct acaggacaac gcgatctggc atacggacgt gacattcacc
    15901 gagacgccgc cgcgcgcgtc gatcctcgcc gcgcacacgc tgcccgagac gggcggcgac
    15961 acgctgtggg gcagcggctt cgccgcgtac gacgcgctgt ccgggcgcgt gaaggcgcag
    16021 ctcgacggcc tcaccgcgca gcacgatttc acgaagtcgt ttccgctgaa acgcttcggc
    16081 gtcaccgccg aggatcgcgc gcgctgggag aagacgcgcg cgacgcatcc gagcgtcgcg
    16141 catcccgtcg tgcgcacgca cccggagacc ggccgcaaga cgctgttcgt caacgaaggc
    16201 ttcacgaccg agatcgacgg gctgcccgaa gaggaaggcg ccgcgctgct gcgcttcctg
    16261 ttcgcgcatc agtcgcggcc cgagttcacg ctgcgctggc gctggcagcc gggcgacgtc
    16321 gcgttctggg acaaccgctc gacgatccat tacgcggtga acgactacgg caaagcgcat
    16381 cgggtgatgc accgcgcgac gatcgtcggc gacaggccgt attgagcggg cggcgcgggg
    16441 attccggaga ggcttcgccg gccgcgggtt cgttcgtcgg tcggctcgcc gcttcgttcg
    16501 ccggctcgtt cgcgggcctg ccgtatcggc tcgttcatcg gcccgttcat cggcccgctc
    16561 atcggcccgc ccatcggcgc cgcatggcgc tccgttcgtc gccccgctcg ttcaccggcg
    16621 gctcgtcggc cggccattcg cctgccgcgg gcgcgcgccg tcgcgcgcgt cgcggggcgc
    16681 ggctcgcgcg tcaatccgcg agccccatca gcttcgcgag caccggccac ctcttgagcg
    16741 ccgtgcggta cgcgagccgc gcctgctcgt cgagatagcg cgccggatcg atctcgcgca
    16801 cgtggcgcgc gagccccgca atgtcgtgcg ccggcggcgg cgcgtcgccg cgcgccgccg
    16861 gcgtgttccg attcccgttc gtcatttttc gtcgatccat acgccgtccg gcgtcttcac
    16921 cgcgtagccc gtcggcgtcg tcatcgtcac cgtgccctcg ttctcgccga tcattcgcgt
    16981 ctgcggcaga tcggccgcgt attgcgacag cgtcacgccc ggcttgaacg ggctgttcga
    17041 cacgagattc gccagcagtt gcgcgagcgc gaggaagctc gccggcgcgt cgatcacggt
    17101 ggtcgcgccg tggtcgccct tgaagccgac gagccgcacg ccgaccggcc cgtgcacgat
    17161 ccgcggcgtc ggaatctcgc gcagccccgc cacctgtttc gcgtcgccgc gcagcgccgc
    17221 gccgtgctcg ggcacgaaca cgatcaccgc gcgccgcccc gatgcggcaa tgagatccgc
    17281 gaagcggtcg aagtcgtcca gcagcttgcg cgcgcgcagc gggtacgaat cgaggctcga
    17341 catccggccg cccgtcagct gattgccgtc gtgcaggctg atcgtgttgt agtacagcgc
    17401 gacggggccg gggctcgcgc cgcgtttcgc gtaccagttc gcgagcgtcg cgtagtcgtc
    17461 cttgatcgcc gagccgtcga acgcgtgcat cgcgacgggc gcgtccgcgt tcgggatcat
    17521 cggcgcgttc ggcacgccga tgttctcgcg gatcaactgg agaaagttgt cgaagtggcc
    17581 gtcgtggttg agcagcgtct gcggcgcgaa gccggcggcc gcgagttgcc cgaacagatg
    17641 gcactgcgcg ggcgcgggct tgtacaggtc cgcgtgcgcc tcctgcccgc agctcgcgcg
    17701 cagcacgcgg atcgcggccg ggccgctgta gctcgccgcc gtgctgaaat tcgtgaacag
    17761 atagtcgaaa tggccaagca gcggatgatt gcgcagcctc gcgacgtcga ggtcgtccca
    17821 cgacagcgag cacacatgca gcacgatcac gtcgaactgc gtcgccggat cggcgctcgg
    17881 ccggccgaac gtcacctgcc gctgcgattc ctgcgagcgg aacgcggcga gcgccgcgtt
    17941 gtgatcctgc ggctgcacgg cgcggcccgt tccggccggc ccgggcacgg ccgcggcagc
    18001 cgcgtcgagc cgcgcgagcg ccgcgctgcc cgcctgccac accggcagcg cgatcagcgc
    18061 gagcagcacg aacgtcgcca cgcgcagcca gcgattgacg atcagatagc cgatcacgac
    18121 gccgagcgcg gccaatgcga gcatcggcgg cacgaagcgc ggcacgagct ccatccagta
    18181 gccggcgctg aacgcgcgca ggccgccgag cgtttcgacg agccgcgcga gtggcggcac
    18241 gtccgcttcg cgatacatca gcggcaccgc gagcgccagc gcgagcgcgt ggcgcagcag
    18301 ccgcacgccg cgccgcctcg ccggcgcgct cagcgcgagc gccagcgcga aaccgagatt
    18361 cgcgatccac aacggcttca agtggcccgc cgcgaacaga tagagcttca gaatgaaata
    18421 cagattccag aacgtcatcg acgcgactcc gtcatcagtt gaatccgcgc gtcaatgacg
    18481 cgtccggtcg gccgcgcgcc gcgcccgcac cgcgctcgtc gcggcccgca gcatccgtgc
    18541 gtagcattcg aaccccatcg acagcacctc cttcagcccg cgcagcggcg catcgtcgtg
    18601 ctcggcgcgc gcgtcgcgcc agtcgagcca cgcatccgcg cggccgaacg tgcactgcac
    18661 gagctgccgc tcctgctcga gcgtcaatgg ctcgaactgc acgccgagat gcgcggcgtc
    18721 gacgcgggtc acgcgcaccg gaaaatggaa cgggcgatcg ccgcggctca cgcatacgtc
    18781 gagcgtatcg ccgagcgcga tgcgcgcgag cggcaccgcg tcgagcccca agccgcccgc
    18841 cgaataatcc ttcgtgtggc acgcggccgt cgtgccgtcg gcgagcaaca gcgtcgccgg
    18901 cacccgcatc gcgacccggt gcgtgacgcg cacctgtttc gcctcgcgcg cgaccgcgag
    18961 cgccgcgccg agcatcgcga ggttgtacaa cgcccacgcg acgttcatca ggatcgtcga
    19021 cgcttcgtcg ccgccgctcg cggcgagacg cacgccgccc gccgcgatcg ccgcgacgtt
    19081 cagcacgaac agcgcgagat agggcctgga cgtcgcccag tcgacgtagc cttcgtcgat
    19141 gcgcccgccc ttcgcggtca cattgaagcg gccgtgcctc gggctcagga acgcgagcgt
    19201 cgtcggcagc gcgatgtacc acgcgagcac cgattcgtac acctcggccc agaacgaatg
    19261 ccgaaagcgc ccctgcatcc gcgcgttcgc gacgtgcgcg agcgccatgt acggcagcac
    19321 gtagctcgcg agcgcgagcg ccgacgcgtt gatgaaatac aaatggaaga acagatacgc
    19381 gatcggcatc gtcaggaaca cgagccgcgg gatgccgtag aagaaatgca gcatcgcgtt
    19441 gccgtagcac acgcgctgga agaagccgag gccgcggccg acgaacgggt tgtcgatccg
    19501 gaagatctgc gccatcccgc gcgcccagcg cgcgcgctgc cggatgtggc ccgcgaggct
    19561 ttcggtcgcg aggccggcgg cctgcacggt cggcagatag gcgctcgtgt agccgcggcg
    19621 gtgcagcttg agcgcggtgt gcgcatcctc ggtgacggtc tcgatcgcga cgccgccgat
    19681 tgcttcgagc gggccgcgct tgagcaccgc gcacgaaccg cagaagaacg cggcgttcca
    19741 cagatcgttg cccgcctgca cgaggccata gaacaggctg ccctcgttcg gcacgcggcg
    19801 gaacgtgccg aggttgcgct cgaacgggtc cggcgagaag aaatgatgcg gcgtctgcac
    19861 gagcgcacag ttcggatcgc gaaggaacgc gcccatcgtc gtctgcagga acgagcgcgt
    19921 cggcacgtga tcgcagtcga agatcgcgat gtattcgccg tgcgtgcgcg caagcgcgct
    19981 attgatgttg ccggccttcg cgtggcgatt gtcgtcgcgc gtcagatagc cgatgcccgc
    20041 gtcgcgcgcg aacgcctcga actccgggcg gcggccgtcg tcgagcagat agacgttgag
    20101 cttgtccgcc ggccaatcga ggctttgcgc ggcgaagatc gtcggcttca cgaccgcgag
    20161 cggctcgttg tacgtcggaa tgtagacgtc gacgctcggc cagccggcgg gatcgtccgg
    20221 caggcgcgcg accgggcgct cgagcggcca cgcggtctgc acgaagccga gcacgaggat
    20281 gagccacgtg tacgcctcgg ccgcgtacag cagatagccg acgcacgcct cgaccggtgt
    20341 gcgcaaatcg agcgtctcgg tgctgcgcca ccagatgtag cgggccatcg cgagcagcgc
    20401 gaacgtcgcg agcgcgagcg tcggcaagcg gccgggcacg cggcgcagcg cgagcgcgag
    20461 cgcggcgagc gtcgcgaaga acgcgaactg gccggcgggc gcgagcggcg acgtgccggc
    20521 cgcgagccac agcgcaacgc ccgccgccgc gctcgccggc aacagccagc ggcgtgcgac
    20581 ggcccgctgc gcgccctgct cgaggcgcg
//
