LOCUS       NZ_CP009477            20612 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Burkholderia pseudomallei MSHR2543 chromosome II, complete sequence.
ACCESSION   NZ_CP009477
VERSION     NZ_CP009477.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei MSHR2543
  ORGANISM  Burkholderia pseudomallei MSHR2543
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3205965)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.E.,
            Davenport,K.W., Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C.,
            Coyne,S.R., Broomall,S.M., Li,P.E., Teshima,H., Gibbons,H.S.,
            Palacios,G.F., Rosenzweig,C.N., Redden,C.L., Xu,Y., Minogue,T.D. and
            Chain,P.S.
  TITLE     Complete genome sequences for 59 burkholderia isolates, both
            pathogenic and near neighbor
  JOURNAL   Genome Announc 3 (2), e00159-15 (2015)
   PUBMED   25931592
  REMARK    Erratum:[Genome Announc. 2016 Apr 21;4(2):e00313-16. doi:
            10.1128/genomeA.00313-16. PMID: 27103731] Publication Status:
            Online-Only
REFERENCE   2  (bases 1 to 3205965)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.,
            Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C., Coyne,S.R.,
            Broomall,S.M., Li,P.-E., Teshima,H., Gibbons,H.S., Palacios,G.F.,
            Rosenzweig,C.N., McMurry,K., Redden,C.L., Xu,Y., Currie,B., Mayo,M.,
            Minogue,T.D. and Chain,P.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-SEP-2014
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; Allpaths v.
            44837; Phrap v. SPS - 4.24; HGAP v. 2.2.0
            Genome Coverage                   :: 463x
            Sequencing Technology             :: Illumina; PacBio, 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000959225.1-RS_2024_06_16
            Annotation Date                   :: 06/16/2024 14:42:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,715
            CDSs (total)                      :: 6,638
            Genes (coding)                    :: 6,472
            CDSs (with protein)               :: 6,472
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 166
            CDSs (without protein)            :: 166
            Pseudo Genes (ambiguous residues) :: 0 of 166
            Pseudo Genes (frameshifted)       :: 85 of 166
            Pseudo Genes (incomplete)         :: 110 of 166
            Pseudo Genes (internal stop)      :: 20 of 166
            Pseudo Genes (multiple problems)  :: 39 of 166
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:58:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1417845
            Orig. end                         :: 1438457
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009477.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The DNA was obtained from USAMRIID.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="9"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20612
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10612](-)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10612)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     misc_feature    complement(122..137)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.78"
                     /tool="antismash"
     gene            484..762
                     /locus_tag="BG16_RS05850"
     CDS             484..762
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004528146.1"
                     /locus_tag="BG16_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_009924482.1"
                     /transl_table=11
                     /translation="MGDEERAATNHDVCFADVDAARAASIGLARNDGDLLIRLVAMCRQ
                     TGGADRRGSSRGARLMVAREFARRELAARPEHRNVYPVHPIGFSAEA"
     gene            complement(871..1482)
                     /locus_tag="BG16_RS05855"
                     /old_locus_tag="BG16_4883"
     CDS             complement(871..1482)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204410.1"
                     /locus_tag="BG16_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4883"
                     /product="LysE family translocator"
                     /protein_id="WP_004204410.1"
                     /transl_table=11
                     /translation="MSLSSLALFAAALLVAAGSPGPSIAALVARVLTNGVRDVLPFLAA
                     MWLGEVIWLTCAVAGLTALAHTFAFGFLVLKFAGIAYLVFLAWKMWFAPADEPSGQLPR
                     GQSPLRMFLTGIAVTLGNPKIMIFYVALLPTMVDLSRAGAVAWLELTLTLLVVLITVDC
                     AWAWLAARARKLLTSRRAMKAANRASAAAMAGAAVAIAMR"
     gene            1654..2133
                     /locus_tag="BG16_RS05860"
                     /old_locus_tag="BG16_4884"
     CDS             1654..2133
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968142.1"
                     /locus_tag="BG16_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4884"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_004551571.1"
                     /transl_table=11
                     /translation="MAAIEAAAARRFDDIGMPHIASSPPTDLADLRERIDDDRALVAFD
                     AEGLRIVGFAIYRMLGASRLYLEEVDVAPEHAGRRIGSALIEAVAARARAAGARQVVLS
                     TFRHVPWNAPYYRRLGFVELDGNTLDAALTAIRATHVAHGLDESQRVFMARMVHE"
     gene            complement(2274..3335)
                     /locus_tag="BG16_RS05865"
                     /old_locus_tag="BG16_4885"
     CDS             complement(2274..3335)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015602739.1"
                     /locus_tag="BG16_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4885"
                     /product="alkene reductase"
                     /protein_id="WP_004523984.1"
                     /transl_table=11
                     /translation="MPSLFDPLTIGELTLANRIIMAPLTRARAGDTRTPNALMARYYAE
                     RASAGLIISEATSVTPQGVGYASTPGIWSPEQVDGWRLVTDAVHAAGGRIFLQLWHVGR
                     VSDPVFLDGALPVAPSAIAPGGHVSLVRPQRPYVTPRALELDEIPGVVAAFRRGAENAR
                     AAGFDGVEVHGANGYLLDQFLQDSANRRTDAYGGSIENRARLLLEVVDAAIDVWSAARV
                     GVHLAPRGDAHTMGDSDPAATFGHVARELGRRRIAFLFARESFGGDAIGQQLKAAFGGP
                     FIVNENFTLDSAQAALDAGQADAVAWGKLFIANPDLPRRFKLNAPLNEPNAATFYAQGE
                     VGYTDYPALESAA"
     gene            complement(3385..3690)
                     /locus_tag="BG16_RS05870"
                     /old_locus_tag="BG16_4886"
     CDS             complement(3385..3690)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195494.1"
                     /locus_tag="BG16_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4886"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_004195494.1"
                     /transl_table=11
                     /translation="MTFDADAIHKALASPVRRTILAWLKAPDKHFPASQAGPFPQGVCA
                     GQIDALCGLSQSTVSAHLATLERAGLVTSTRVGQWAFFKRNDAVIQAFLDSLQRGL"
     misc_feature    complement(3742..3760)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.92"
                     /tool="antismash"
     gene            complement(3880..4428)
                     /locus_tag="BG16_RS43000"
                     /old_locus_tag="BG16_4887"
     CDS             complement(3880..4428)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024189.4"
                     /locus_tag="BG16_RS43000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4887"
                     /product="YXWGXW repeat-containing protein"
                     /protein_id="WP_229274719.1"
                     /transl_table=11
                     /translation="MFVAGCRSSAPRSPAWASAAAPRRSSRPGRRPRRPDRSPDHRAPA
                     QPRPARPPYPGRPERPPPPLRRERRPAPPRPRGYVWTNGYWRWPGGRSVWIPGRWIAQR
                     PGHRWIPGCWRQRADVRLYIDGRWNCVRGEPHAVCRESRETHRGTRGGGASPPTNTARP
                     FSAQRFVERPCAPARAGRR"
     misc_feature    4536..4551
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(4813..4826)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.3"
                     /tool="antismash"
     misc_feature    4841..4850
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.58"
                     /tool="antismash"
     misc_feature    4844..4858
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.79"
                     /tool="antismash"
     gene            5027..6151
                     /gene="omp38"
                     /locus_tag="BG16_RS05880"
                     /old_locus_tag="BG16_4888"
     CDS             5027..6151
                     /codon_start=1
                     /gene="omp38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184655.1"
                     /locus_tag="BG16_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4888"
                     /product="porin Omp38"
                     /protein_id="WP_004523988.1"
                     /transl_table=11
                     /translation="MNKTLIVAAVAASFATVAHAQSSVTLYGVLDAGITYQSNVATPSG
                     SGKSLWSVGAGVDQSRFGLRGSEDLGGGLKAIFTLESGFNIGNGRFNNGGGMFNRQAFV
                     GLSSNYGTVTLGRQYDATQDYLSPLSATGTWGGTYFAHPLNNDRLNTNGDVAVNNTVKF
                     TSANYAGLQFGGTYSFSNNSQFANNRAYSAGASYQFQGLKVGAAYSQANNAGANTTGAT
                     DPLTGFNIGGTNAASIQGRSRVYGAGASYAYGPLQGGLLWTQSRLDNLANGAPTIRADN
                     YEANVKYNLTPALGLGVAYTYTNAKANGESTHWNQVGVQADYALSKRTDVYAQAVYQRS
                     SKNANASIYNGDLSTPFSTSINQTAATVGLRHRF"
     gene            complement(6370..6768)
                     /locus_tag="BG16_RS05885"
                     /old_locus_tag="BG16_4889"
     CDS             complement(6370..6768)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195489.1"
                     /locus_tag="BG16_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4889"
                     /product="GreA/GreB family elongation factor"
                     /protein_id="WP_004537171.1"
                     /transl_table=11
                     /translation="MRNRIYQLTELDVARLEKHAERNPRYQEMLDTLLERADIVEPNKI
                     QANVVTMNSQIKLLDETAGQDMAWTIVYPDAANFEQGRLNVFSPVGMALLGSRCGERVK
                     VTLPGGADATLKIVEIVYQPEASGDYAH"
     misc_feature    complement(7026..7042)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.83"
                     /tool="antismash"
     misc_feature    7033..7051
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.64"
                     /tool="antismash"
     misc_feature    complement(7034..7052)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.4"
                     /tool="antismash"
     misc_feature    complement(7036..7053)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.31"
                     /tool="antismash"
     misc_feature    7042..7055
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.81"
                     /tool="antismash"
     gene            7288..7629
                     /locus_tag="BG16_RS05890"
                     /old_locus_tag="BG16_4890"
     CDS             7288..7629
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900400.1"
                     /locus_tag="BG16_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4890"
                     /product="DUF4148 domain-containing protein"
                     /protein_id="WP_004195487.1"
                     /transl_table=11
                     /translation="MKSFVYAAVAASILATPLASFAQADQQPPLTREQVRSELVQLEQN
                     GYKPEAGETQYPANVQAASQRMLPAQQTLTHADTSGYGVQPAGAAESGGRASRSPASPA
                     FGHSIYFGN"
     gene            complement(7834..8298)
                     /locus_tag="BG16_RS05895"
                     /old_locus_tag="BG16_4891"
     CDS             complement(7834..8298)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195485.1"
                     /locus_tag="BG16_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4891"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_004195485.1"
                     /transl_table=11
                     /translation="MSLTVAQILRSKPDSGRTIHMVEKSDSVYNAIKLMAEKSIGALLV
                     MDGANIAGIVTERDYARKVVLLDRSSKATRVEEIMTSKVRYVEPTQTSDECMALMTEHR
                     MRHLPVLDDGKLVGLVSIGDLVKSVIADQQFTIDQLEHYIHGIPAAAHPQ"
     misc_feature    8329..8338
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            8475..9128
                     /gene="ribA"
                     /locus_tag="BG16_RS05900"
                     /old_locus_tag="BG16_4893"
     CDS             8475..9128
                     /EC_number="3.5.4.25"
                     /GO_function="GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ribA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195483.1"
                     /locus_tag="BG16_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4893"
                     /product="GTP cyclohydrolase II"
                     /protein_id="WP_004195483.1"
                     /transl_table=11
                     /translation="MKSSHPDSPQPDDGAAPECVTLVATATLPTRYGTFTSYAFRVAGG
                     DAEHLALVMGDVAEQPSVLTRLHSECLTGDVFGSYRCDCGEQLDLSLRYIAAEGRGVLL
                     YLRGHEGRGIGLSNKIRAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRILKVTSV
                     RLMSNNPKKFDTLARHGIPVCERVALAVPVREENERYIRTKQLKFGHYYFDENE"
     gene            complement(9091..9912)
                     /locus_tag="BG16_RS05905"
                     /old_locus_tag="BG16_4892"
     CDS             complement(9091..9912)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004554929.1"
                     /locus_tag="BG16_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4892"
                     /product="hypothetical protein"
                     /protein_id="WP_004531723.1"
                     /transl_table=11
                     /translation="MLPTFDAGETRIAVAFPSFAERLPLVRLGRQGLVFRARGAMPPVC
                     GLPRSATLYLDDEPLCTLRLVIREVERCDDGAHDLTMQPSAANGDALLWHALRTRCRHA
                     RAPLAPRAPDERPAPATQASARRRDTAPRADAARPESGAPRAAGTGVRMTRSAAFRLAD
                     RGDALFFADWLEYHFDELRALAQGLSPRLHLNELERDLAGDEVDVRFVYDIDGHADRRM
                     LTDCARQACDWIATEVRRRFDLPIAEQRFGARKPRRATRAIRFRRNNSGRT"
     gene            complement(10001..10612)
                     /gene="bspI1"
                     /locus_tag="BG16_RS05910"
                     /old_locus_tag="BG16_4894"
     CDS             complement(10001..10612)
                     /codon_start=1
                     /gene="bspI1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004523992.1"
                     /locus_tag="BG16_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4894"
                     /product="N-acylhomoserine lactone synthase BspI1"
                     /protein_id="WP_004523992.1"
                     /sec_met_domain="Autoind_synth (E-value: 6.8e-26, bitscore:
                     88.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTFVHGDGRLPSDLAADLGLYRHRVFVEQLGWKLPSASEGFERD
                     QYDRDDTVYVFARDDDGEICGCARLLPTTRPYLLKELFPTLVAQDMPLPQSAAVWELSR
                     FAANAEDPAGGGNPAWAVRPMLAAVVECAARLGAKQLIGVTFLSMERLFRRIGVHAHRA
                     GPAQQIDGRMVVACWIDLDAQTLAALDLDPLLCAPPAEAA"
     misc_feature    10596..10609
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.13"
                     /tool="antismash"
     misc_feature    complement(10804..10817)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            complement(10837..11280)
                     /locus_tag="BG16_RS05915"
                     /old_locus_tag="BG16_4895"
     CDS             complement(10837..11280)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015603338.1"
                     /locus_tag="BG16_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4895"
                     /product="DUF4902 domain-containing protein"
                     /protein_id="WP_004528152.1"
                     /transl_table=11
                     /translation="MNSPWLHRFRGSSTDGYVRLPMHAFAELRLVHVSSGIDSGLLVEL
                     RASDIDARIAGYTEWERPSSAGAAHLTVGWDWYIDGATGAFVIAWGDVRSNVMGVDGNG
                     LDIGMDPTSAALSRRLAQLNWPSAVTAAMLRRGDFAHAGPTLQ"
     gene            11354..12073
                     /gene="bpsR"
                     /locus_tag="BG16_RS05920"
                     /old_locus_tag="BG16_4896"
     CDS             11354..12073
                     /codon_start=1
                     /gene="bpsR"
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184923.1"
                     /locus_tag="BG16_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4896"
                     /product="autoinducer-binding transcriptional regulator
                     BpsR"
                     /protein_id="WP_004184923.1"
                     /transl_table=11
                     /translation="MELRWQDAYLQFSAAENEQQLFQQIAAYTKRLGFEYCCYGIRVPL
                     PISKPVVAIFDTYPNGWMERYQEMNYLEVDPTVREGALSSNMIVWPEASASDATTLWSD
                     ARDHGLAVGVAQSSWASRGVFGLLTIARHTDRLTSAEINHLTLQANWLANMSHSLMSRF
                     LVPKLAPESGVALTHREREVLCWTGEGKTACEIGQILSISERTVNFHVNNILDKLGATN
                     KVQAVVKAIAMGLIDAP"
     gene            complement(12109..12825)
                     /locus_tag="BG16_RS05925"
                     /old_locus_tag="BG16_4897"
     CDS             complement(12109..12825)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897347.1"
                     /locus_tag="BG16_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4897"
                     /product="MgtC/SapB family protein"
                     /protein_id="WP_004184903.1"
                     /transl_table=11
                     /translation="MTFEFALRLFTAFACGVAIGLERQIRQRTAGLRTITLVASGACLF
                     VTLGVLTGNGIPGVTQIAAYVVSGVGFLGGGVIMRDKGSIQGINTAATLWCSAAVGVLS
                     GAGHYLPALAGTGVVLLTNTLLRGVSQAINATPVSNADLVREYQITVICLASDEVHIRT
                     LLSNSMYAKPLSFQSLTSEDVPREADAPERIKVTATLKLHPKDQQKLEQIASRMSMEKS
                     ISSVSWTAKEAEPLME"
     gene            complement(13442..14647)
                     /locus_tag="BG16_RS05930"
                     /old_locus_tag="BG16_4898"
     CDS             complement(13442..14647)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900392.1"
                     /locus_tag="BG16_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4898"
                     /product="metallophosphoesterase"
                     /protein_id="WP_004195471.1"
                     /transl_table=11
                     /translation="MRRVSSFLLRLTIIGVLLHVYVGFRLLPELASPAARYAGALWLVG
                     SCLLIPLGMLSRVFERQPLGDRVAWAGLLAMGFFSSLLVLTLARDVLLASLVTVDALAP
                     GAVSLAQWRIQTAAGVPLAALAVSVVGFVNARRRARVVDVAVPIDDLPAALDGFTIVQI
                     SDIHVGPTIKRGYVEAIVDAVNRLAPDLVAVTGDVVDGTVAQLAGHAAPLGRLRARHGA
                     FVVTGNHEYYSGADEWIAEFRRLGLDVLLNEHRTLDHGDGRLVIAGVTDYSAGHFDPAH
                     RSDPSAALAGAPADVRIRVLLAHQPRSATAAADAGFTLQLSGHTHGGQFFPWNFFVRLQ
                     QPFTAGLARLNGLWVYTSRGTGYWGPPKRLGAPSEITRVRLVRGEGNRTRAPASVTLNA
                     ER"
     gene            complement(14710..15294)
                     /locus_tag="BG16_RS05935"
                     /old_locus_tag="BG16_4899"
     CDS             complement(14710..15294)
                     /EC_number="1.1.1.298"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004532724.1"
                     /locus_tag="BG16_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4899"
                     /product="malonic semialdehyde reductase"
                     /protein_id="WP_004195469.1"
                     /sec_met_domain="PF00881 (E-value: 3.8e-15, bitscore: 53.7,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSDSALDQIFRTARTHNAWQPKPVDDALLRELIDLVKWGPTSA
                     NSSPARFVFVKSPEAKAKLKPALSEGNLAKTMAAPVTVIVGMDMAFHDHLPKLFPHADA
                     RSWFAGNDALIEATAFRNASLQGAYLIVAARALGLDAGPMSGFDQAAVDAAFFAGTSIK
                     SNFLVNLGYGDAAGLFPRSPRFSFDEIARIE"
     gene            15427..16053
                     /locus_tag="BG16_RS05940"
                     /old_locus_tag="BG16_4900"
     CDS             15427..16053
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004528155.1"
                     /locus_tag="BG16_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4900"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_004528155.1"
                     /transl_table=11
                     /translation="MDDLFDDLPRPDADWHPDWLAPADADRFHARLVDEVAWRQDTMRT
                     PRGLLPLPRLTAWQGEPDALYVYSGIRNEPAPWTPAVLELKRRVEAASRARFNSVLLNR
                     YRNGFDSMGWHADDEPELGAEPVIASLSLGATRVFDLRHNETGVTHAYRLTNGSLLVMR
                     GRTQHAWRHRVPKEPAVRGERINLTFRWVSAPPAAERRARPRSRG"
     misc_feature    15429..15443
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.46"
                     /tool="antismash"
     gene            16140..17090
                     /locus_tag="BG16_RS05945"
                     /old_locus_tag="BG16_4901"
     CDS             16140..17090
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004528156.1"
                     /locus_tag="BG16_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4901"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_045587400.1"
                     /transl_table=11
                     /translation="MAKTTTTAAGRPAADAASAKSRRAAAGARPELDAADDEVAGGASS
                     YLVPGLERGLRILSEFSAREPVLSAPELSKRIGIPRTTTFRLLQTLEALGFIERANGDR
                     HFRLGIGVLRLGFEYLNSLELTDLGAPVLERLRDAAGLSTHLLIRDRRDVVFVAKAQSN
                     APMFGSVKVHVGTRLPAHATVHGHVLMGDLTRDAMRQLYPEKRLEAFTEHTPATVDELY
                     ERVRHYARLGYALSEGAFESGISAVTAPVRDHSGSIVAAITATVPRSEIGAVDEKERLV
                     ELVCGAAVDLSQRLNYRPLDGDPTVAHARHKVALL"
     gene            complement(17407..18495)
                     /locus_tag="BG16_RS05950"
                     /old_locus_tag="BG16_4902"
     CDS             complement(17407..18495)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009939921.1"
                     /locus_tag="BG16_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4902"
                     /product="porin"
                     /protein_id="WP_045587401.1"
                     /transl_table=11
                     /translation="MVKHAVATLLGALAAAGAWAQSSVTLYGSLDAGVAYVNNVGGGAK
                     WSMIQGNTQPDRWGLKGVEDLGGGLKAIFQLENGFYTNNGQMAAAGTMWNRQAFVGLNS
                     DRLGALTLGHQTPFNFDWLDPLSSAFLAQSWYAFHPGNLDQLADTSTVPFNNSVKYRSP
                     AFAGFTVGAMLGFGNTTNFSTGRTMSFGVNYANGPFKAAAVYSNEHDQAFPMATVGGIA
                     GPGGTFQGMPVASYVAKKAQNMGAGLSYRFGPLLVHGLYTRVKLQANGHSDTFQSYDAG
                     ANYQSSPFNVIAGGAATSTLAGRRWTQFELGDTYSLSKRTQLYVNVLYEHASGNAKAAF
                     FTAGASSTANQVIVLTGIHHSF"
     misc_feature    18466..18482
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.51"
                     /tool="antismash"
     misc_feature    complement(18469..18471)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18927..18941)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.26"
                     /tool="antismash"
     gene            18929..19246
                     /locus_tag="BG16_RS05955"
                     /old_locus_tag="BG16_4903"
     CDS             18929..19246
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006396774.1"
                     /locus_tag="BG16_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4903"
                     /product="non-heme iron oxygenase ferredoxin subunit"
                     /protein_id="WP_004184916.1"
                     /transl_table=11
                     /translation="MSEQWVCAGHAGALSEDSPIEFKRTDGVEIGIYRVGDDVYALENV
                     CPHAYALLTQGFVDEGTVECPLHEAVFDIKTGQCLKGPGGRALKTYAVRLAGEEIQIKV
                     E"
     gene            19248..19559
                     /locus_tag="BG16_RS05960"
                     /old_locus_tag="BG16_4904"
     CDS             19248..19559
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184841.1"
                     /locus_tag="BG16_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4904"
                     /product="recombinase-like helix-turn-helix
                     domain-containing protein"
                     /protein_id="WP_004184841.1"
                     /transl_table=11
                     /translation="MNETTVNFNPLLMPWRAPQPNNVAGKGQIEIPGRMPNLVWQTRKA
                     EPTQYENDLGDALERVFESGATELAEVVAGLNRIGFRAPDGAEWTAERFCAELAALAE"
ORIGIN
        1 ctacagtttg tcgaaacgga cggcgctgta tgcggtcgcg atcggacaga tcgcatcggg
       61 gcgcgggctc ggcagcgacg cgaacggcga tcccgtgaac tacgcgcaga ttcccgtatt
      121 ggcgaacagc aattcgaacc ggcagctcgc gatgatggcg ggggtaaagg tggatttctg
      181 acgggcggcg tgtttggcac tgcttgggat gccgccttgg cgcggtgtgt ttcgcttggc
      241 gaagcagtcc tgtcgcgtgg cggcgtgcgc gtgcgacgcc agtggaggcc gacgttctcg
      301 ccgcacggtc gtcgcgggcg atgacggatc gcgcaatggt cggcagagcg gccatgaacg
      361 aggcgacttt ggcgccggga tgcgcgggct tgcgcggggt gcgggcggtt ctcgtcgcgt
      421 gccgatgcgg gcggcacgca tgggatgcgc gccgatcatt ggccgcgagc gccgaaaccg
      481 tggatggggg atgaggagcg cgcggcgacg aatcacgatg tctgtttcgc ggatgtcgac
      541 gcggcgcggg ccgcgtcgat cggcttggcg cgaaacgacg gcgatctgct gatcaggctt
      601 gtcgcgatgt gcaggcaaac cggcggcgcg gatcggcgcg ggtcgagccg gggcgcgcgt
      661 ctgatggtgg cgcgggaatt tgcccgtcgc gaactagcgg ctcgcccgga gcatcggaat
      721 gtatatcctg tacacccgat tgggttctcg gccgaggcgt gaaaaaactt gcccatgcag
      781 gcgctgggta cgcgtcgcca cgcgcatttt gacgtgcgtc ggccggtgcg gctggccacg
      841 cgtggtcgcg ccgtgttggc gcgcggccgg tcagcgcatc gcgatcgcga cggcggcgcc
      901 cgccatcgcg gccgcgctcg cgcgattcgc cgccttcatc gcgcggcggc tcgtcagcag
      961 cttgcgggcg cgcgccgcga gccatgccca tgcgcagtcg accgtgatca acacgacgag
     1021 cagcgtcaac gtcaattcga gccatgcgac ggcccctgcg cgagacagat ccaccatcgt
     1081 cggcagcagc gcgacataga agatcatgat tttcgggttg ccgagcgtga ccgcgatgcc
     1141 cgtcagaaac atgcgcaacg gcgactgtcc gcgcgggagc tggccggacg gctcatcggc
     1201 gggcgcgaac cacatcttcc acgcgagaaa cacgaggtag gcgatgcccg cgaacttcag
     1261 cacgagaaag ccgaatgcga acgtgtgcgc gagcgccgtg agcccggcta ccgcgcaggt
     1321 cagccagatc acttcgccga gccacatcgc cgcgaggaac ggcaacacgt cgcgcactcc
     1381 gttggtcagc acgcgcgcga ccagcgcggc gatgctcggg ccgggcgagc cggcggcgac
     1441 cagcagggcg gcggcgaaga gggcgaggct ggatagtgac atgctcaaac tcccgaggcg
     1501 atgcgatgac gatcggttcg tcaacgatcg attatagtga cggctgctcg cacccgatcg
     1561 accatgcgcc attcaccagt gactgcacgc cgctcagccg ctcgaccctg tccaatcggc
     1621 atccgcgccg cacgcgccga cgaagcgccg ctgatggccg ccatcgaagc cgccgccgcg
     1681 cgccgtttcg acgacatcgg catgccgcac atcgcgtcga gcccgccgac cgatctcgcc
     1741 gatctgcgcg agcggatcga cgacgatcgc gcgctcgtcg ccttcgatgc cgaggggctg
     1801 cgcatcgtcg gttttgcgat ctacaggatg ctcggcgcgt cgcgcctcta tctcgaagag
     1861 gtcgacgtcg cgcccgagca tgcgggacgg cggatcggat ccgcgctgat cgaggccgtc
     1921 gcggcgcgcg ctcgcgcggc gggtgcgcgg caggtcgtgc tgtcgacgtt tcggcatgtg
     1981 ccgtggaacg cgccgtatta ccgccgactc ggcttcgtcg aactcgacgg caacacgctc
     2041 gacgccgcat tgacggcgat acgcgcgaca cacgtcgcgc acgggctcga cgaatcgcaa
     2101 cgcgtgttca tggcgcgcat ggtccacgaa tagcgtcaca gccggcgctg gcatgcgatc
     2161 tcgcatgttg aacgatgacg gccgatcgcc gatcgccaat cgcccgaagc gcacggctca
     2221 agccgccgaa accaaaccgt cccaaacgcc ggcgcccggg tccggacacc tcctcacgcc
     2281 gcgctttcca gcgccggata gtccgtatag cctacttcgc cttgcgcata gaacgtagcg
     2341 gcattcggct cgttgagcgg cgcattcagc ttgaagcggc gcggcaggtc cggattcgcg
     2401 ataaaaagct tgccccacgc gaccgcgtcc gcctgtcccg cgtcgagcgc cgcctgcgcg
     2461 ctgtcgagcg tgaaattctc gttcacgatg aatggcccgc cgaacgccgc cttcaattgc
     2521 tggccgatgg cgtcgccgcc gaacgattcg cgtgcgaaca ggaacgcgat gcggcggcgg
     2581 ccgagttcgc gcgcgacgtg gccgaacgta gctgcggggt ccgaatcgcc catcgtgtgc
     2641 gcatcgccgc gcggcgcgag atgcacgccg acgcgcgccg cgctccagac gtcgatcgcc
     2701 gcgtcgacca cctcgagcaa caggcgcgcg cggttctcga tcgagccgcc atacgcgtcg
     2761 gtgcggcggt tcgcgctgtc ctgcaggaat tgatcgagca gatagccgtt cgcgccgtgt
     2821 acctcgacgc cgtcgaagcc ggccgcgcgc gcgttttccg cgccgcggcg gaacgcggcg
     2881 acgacgcccg gaatctcgtc gagctcgagc gcgcgcggcg tcacgtacgg ccgctgcggg
     2941 cgcacgaggc tcacgtggcc gccgggggcg atcgcgctcg gcgcgacggg cagcgcgccg
     3001 tcgaggaaga ccggatccga cacgcggccg acgtgccaga gctgcaggaa gatgcggccg
     3061 ccggccgcgt ggaccgcgtc tgtcacgagt cgccacccgt cgacctgttc gggcgaccag
     3121 atgcccggcg tgcttgcgta accgacgcct tgcggcgtga ccgacgtcgc ctcgctgatg
     3181 atgagccccg cggatgcgcg ctccgcgtag tagcgcgcca tcagcgcgtt gggcgtgcgt
     3241 gtgtcgccgg cgcgggcgcg cgtgagcggc gccatgatga tgcggttcgc cagtgtgagc
     3301 tcgccgatgg tcagcggatc gaacagagaa ggcatgaggg aacctcttcg agtgtggcta
     3361 agcccttgcg gcgggtgggc ggaatcaaag gccgcgctgc agcgaatcga gaaacgcctg
     3421 gatcaccgcg tcgttgcgct tgaaaaacgc ccattggccg acgcgggtcg acgtgacgag
     3481 cccggcgcgc tcgagcgtcg cgaggtgcgc ggacacggtc gactgcgaca atccgcacag
     3541 cgcgtcgatc tggcccgcgc agacgccttg cggaaacggc cccgcttgcg atgcggggaa
     3601 gtgcttgtcg ggcgccttga gccacgcgag gatcgtgcgg cgcacggggc ttgcaagcgc
     3661 tttgtgaatg gcgtcggcat caaaggtcat gggcggcgcg gtgaaatcgc gaatcgtcgt
     3721 ttgccgaagc ttaaatcggc cgatgacgat ataaacagca acactctatt gactaggggc
     3781 gatggaatcc ggcgatcgag gcgatagcgt cattcggcgc cgtcgtgagg aatccgcggg
     3841 ccgccgccgg cgtgcgcgcg cgtttgccgc gtcgctggtt catcttcggc ccgccctcgc
     3901 gggcgcgcag gggcgttcga caaatcgctg cgccgaaaac gggcgcgcgg tgttcgtcgg
     3961 cggcgatgcg ccgccgcctc gcgttccccg atgcgtttcg cggctttcgc ggcaaacggc
     4021 gtgcggctcg ccgcgcacgc aattccagcg tccgtcgata tagagccgca cgtctgcccg
     4081 ttgtcgccaa cagccgggga tccagcgatg cccggggcgc tgcgcgatcc agcggcccgg
     4141 aatccatacg gatcggccgc cgggccagcg ccagtagccg ttcgtccaga catagccgcg
     4201 cgggcgcggc ggtgcggggc ggcgctcgcg ccgaagcggt ggaggcggcc gctcggggcg
     4261 gcccggatac ggcggccgcg cgggacgggg ctgcgccggc gcgcggtggt ccggcgaacg
     4321 atcggggcgg cgaggacggc ggcccgggcg gctgctgcgt cgcggagccg cggccgaagc
     4381 ccaggccggc gagcgaggcg ccgacgaacg acagcctgcg acgaaaatgg cgtcggttca
     4441 tggtgcttca aagcggtgag ctggaagcgg cgcgagccga tcgcgcgccc aggttcgacg
     4501 ctaacgcgcc gcgtgccggc tatcgttacg aatcctgtaa cggtcgtcac ggcacgccgc
     4561 agccgggcgg gacacgggca ttgcaggaat tcatggggtc tgttcggcga tagtcttaca
     4621 ttttcatgac gtagatccgg gtcggatcgg taaaaaatgc cgaccccgcc gcgtttgcgc
     4681 ggaactgctt gttgtttata cgcaaccgtc aagacgctga cacagaagaa tgctcgtggc
     4741 gaccgtgcca aaaagccggt gtcaagaggc caaaaatgtc tatcaaaaca aatacttata
     4801 agaggatcgc atttctatta tttctagttc tggaaaagct tatttcttta ttcgcgaatg
     4861 gcggccctag ggtacacccc taaactcacg gttcccataa cgggcaacca tccgggcgcg
     4921 gccatgcagg tagtttcgca agccgatatg gcgcttccgg gcggttgcag accgtttatc
     4981 gaaacgaggt cgcaaggcct acctttttta aaagggagct ccacgcatga acaagactct
     5041 gattgttgca gcagttgctg catcgttcgc aaccgtcgct cacgcgcaaa gcagcgtcac
     5101 gctgtacggt gtgctcgacg cgggcatcac gtaccaaagc aacgtcgcga cgccgtcggg
     5161 ctcgggcaag tcgctgtggt cggtcggcgc cggcgtcgac caaagccgtt tcggtctgcg
     5221 cggctcggaa gacctgggtg gcggcctgaa ggcgatcttc acgttggaaa gcggcttcaa
     5281 catcggtaac ggccgcttca acaacggtgg cggcatgttc aaccgtcaag cgttcgtcgg
     5341 tctgtcgagc aactacggca ccgtcacgct gggccgtcag tacgacgcaa cccaagacta
     5401 cctgtcgccg ctgtcggcaa cgggcacctg gggcggcacg tacttcgcgc acccgctcaa
     5461 caacgaccgc ctgaacacga acggcgacgt cgcggtgaac aatacggtca agttcacgag
     5521 cgcgaactac gccggcctgc aattcggcgg cacgtactcg ttctcgaaca actcgcaatt
     5581 cgcgaacaac cgtgcataca gcgcgggcgc ttcgtaccag ttccaaggcc tgaaggtcgg
     5641 tgcggcgtac tcgcaagcta acaacgctgg cgcgaacacc acgggcgcaa cggatccgct
     5701 gacgggcttc aacatcggcg gcacgaacgc agcaagcatc caaggccgtt cgcgcgtgta
     5761 cggcgccggc gcaagctacg cttacggccc gctgcaaggc ggcctgctct ggacgcaatc
     5821 gcgtctcgac aacctggcaa acggcgcgcc gaccatccgt gccgacaact acgaagcaaa
     5881 cgtgaagtac aacctgacgc cggctctggg tctgggtgtt gcttacacgt acacgaacgc
     5941 gaaggcgaac ggcgaaagca ctcactggaa ccaagttggc gtccaggccg actacgcgct
     6001 gtcgaagcgc accgacgtgt acgcacaagc cgtgtaccag cgttcgtcga agaacgcgaa
     6061 tgcgtcgatc tacaacggcg acctcagcac gccgttcagc acgtcgatca accaaaccgc
     6121 agcgacggtt ggtctgcgtc accgcttcta agcttgacgg ctggctcgtc cagtctcgaa
     6181 aaggcgcctt cgggcgcctt tttttatgcg cgatgcgcat gcgatgcgcg ccgcgcggaa
     6241 aaaaaaaagc gaggcctgcg catgcatcct cgctttggcg tggcggccgt tgccgattcg
     6301 tcgccgctca cgcgggccgg cgatcgttcg gcggccgcgc cgcattcgcc gatccgtcgt
     6361 cgtgcggcct tagtgcgcgt agtcgccgct cgcttccggt tgatagacga tctcgacaat
     6421 cttcagcgtc gcgtccgcgc cgcccggcag cgtcactttg acccgctcgc cgcagcgcga
     6481 gccgagaagc gccatgccga ccggcgaaaa cacgttcaat cggccttgct cgaaattggc
     6541 cgcgtccgga tagacgatgg tccaggccat gtcctggccg gctgtctcgt cgagcagctt
     6601 gatctgcgag ttcatcgtga cgacgtttgc ctgaatcttg ttcggctcga cgatatcggc
     6661 gcgctcgagc agcgtgtcga gcatttcctg atagcgcggg ttgcgttccg catgcttttc
     6721 gaggcgtgcg acatcgagtt cggtgagttg gtaaatcctg tttctcatga cagtctccaa
     6781 atgatcggct tgggtggcgt ggccaacccg ggatcgcccg gagcctgact gacgcggctc
     6841 cgggatggag actgccgtca gatcaagcgc cgggccgcgg cgagcggcgc tgcaagcgtg
     6901 cttcgaagga ggggacgcat cgccgccgcg gccccggccg cgcgcgtacc gcgcgtgcgg
     6961 tgcgcaagaa aggcggggga ggtcggcgtg cgcatgagcg aggcgatcaa acgaaaggcg
     7021 aatgacggtt caaactttac aaatatacaa caaaacgacc gttcagacag ccgacagacg
     7081 gttgcgcgaa gcgttcctcc attgttgccg agatggtgct tttaaccggc tttcggtccg
     7141 actacagtcg gctatttttg tcattggtgc aacgctgtat gttcaaagta ggggtttccc
     7201 cttgttgttc cggtgactag actgaaatca atcgcttccg gcaagggtgc cgggagcgac
     7261 gcaaatacaa cattccggag gtcaatcatg aaatcgttcg tctatgcagc cgttgccgct
     7321 tcgatcctcg ccacgccgct tgcatcgttc gcgcaggccg accagcagcc gccgttgacc
     7381 cgcgagcagg tgaggtccga gctggtccag ctcgaacaga acggctacaa gcccgaagca
     7441 ggcgagaccc agtacccggc gaacgtgcag gctgcgtcgc aacggatgct gcctgcgcag
     7501 cagacgctta cgcatgccga tacgagcggc tatggcgttc agccggccgg cgcggcggaa
     7561 tccggcggcc gcgcgagccg atcgccggct tcgccggcat tcggtcattc gatctacttc
     7621 ggtaactgat cgaatcgagc ggtcagctcc agtgtgagcc cggcatcgcc gggcgcccgt
     7681 cagcccacgc caagaggtcg attctcaaac cgcgagcccg tgcgatgcgt cgggcccgcg
     7741 ggccaggagc cgaacctccg tcgccgcatt tcggcggctt tgcccagacg cgatgcgttt
     7801 gggcattttt tgatgggcgt tgcggcgcgc ggctcattgc ggatgcgcgg cggccggtat
     7861 tccgtggatg taatgctcca attgatcgat cgtgaactgt tgatcggcga tcacgctctt
     7921 cacgagatcg ccgatcgaca cgaggccgac gagcttgccg tcgtcgagca cgggcaagtg
     7981 gcgcatccgg tgttccgtca tcagggccat gcattcgtcg ctcgtttgcg tcggttcgac
     8041 gtagcggact ttcgacgtca tgatttcctc gacgcgtgtc gctttcgacg aacggtcgag
     8101 gagtaccacc ttgcgcgcgt aatcgcgttc cgtcacgatg ccggcaatgt tcgcgccgtc
     8161 catcacgagc agcgcgccga tgcttttctc ggccatcagc ttgatcgcgt tgtagacgga
     8221 gtcggacttt tcgaccatgt gaatcgtgcg ccccgaatcg ggcttcgacc tgagaatctg
     8281 tgcgacggtg aggctcatac gctgtctccc ttggctgggc gattcacgga aggcggcgcg
     8341 cagccgccgc gtcgggtgaa gaatccagta tagatcggcg tccgcgggcg ggtgcgtcca
     8401 gtgcgcagat tagcggtaaa ctccgtgcac tcgccatcca gaacatacct taatcctttc
     8461 gtttgatgca ttccatgaag tcttcgcatc ctgactcgcc gcagccggac gacggcgccg
     8521 cgcccgagtg cgtgacgctc gtcgccaccg cgacgcttcc tacccgctac ggcacgttca
     8581 cgtcgtatgc gtttcgcgtg gcgggcggcg atgccgagca cctcgcgctc gtgatgggcg
     8641 acgtcgccga gcagccgtcg gtgctgacgc ggcttcattc cgagtgcctg acgggtgacg
     8701 tgttcggctc gtatcgatgc gattgcggcg agcagctcga tctctcgctg cgctacatcg
     8761 cggccgaagg gcgcggcgta ttgctgtatc tgcgcggcca cgaaggccgc gggatcggcc
     8821 tgagcaacaa gatccgcgcg tatgcgctgc aggagcaggg gcgcgacacc gtcgaggcga
     8881 acctcgacct cgggctaccc gacgacgcgc gcgaatacga ttccgccgcc gcgatcctgc
     8941 gcatcctgaa agtcacgtcc gtgcgactga tgagcaataa tccgaagaag ttcgacacgc
     9001 tcgcgcggca cggtatcccg gtctgcgagc gcgtcgcgct cgccgtgccg gtgcgcgagg
     9061 agaacgagcg ctatatccgc acgaagcagc tcaagttcgg ccactattat ttcgacgaaa
     9121 acgaatagcg cgcgtcgcgc ggcgcggctt gcgcgcgccg aagcgctgct cggcgatcgg
     9181 cagatcgaag cggcggcgca cttcggtcgc gatccagtcg caggcctgcc gtgcgcaatc
     9241 ggtgagcatc cggcggtccg catggccgtc gatgtcataa acgaagcgca catcgacctc
     9301 gtcgcccgcc aggtcccgtt cgagttcatt caggtgcagc cgcggcgaca ggccttgcgc
     9361 gagcgcgcgc aattcgtcga agtgatattc gagccaatcg gcgaaaaaga gcgcgtcacc
     9421 gcgatccgcg agacggaacg ccgcgctgcg cgtcatgcgc acgccggtgc ccgccgcgcg
     9481 cggtgcgccc gattcggggc gcgccgcgtc ggcgcgcggt gcggtatcgc gccggcgggc
     9541 cgacgcctgc gttgccggtg ccgggcgctc gtccggcgcg cgtggtgcga gcggcgcgcg
     9601 cgcgtgtcgg catcgcgtgc gcagcgcgtg ccagagcagc gcgtcgccgt tcgcggccga
     9661 cggctgcatc gtcagatcgt gcgcgccgtc gtcgcaacgc tcgacttcgc gtatcacgag
     9721 ccgcagcgtg cagagcggct cgtcgtcgag atacagggtc gcggagcgcg gcaatccgca
     9781 gacgggcggc atcgcgccgc gcgcgcgaaa cacgagtccc tgtctgccga gccgcacgag
     9841 cggcaggcgt tcggcgaacg acgggaacgc gacggcgatg cgggtttcgc cggcatcgaa
     9901 cgtagggagc atcgcgcgaa ataccgttga atggtccacg gtgtagaggt ctccttgaat
     9961 gacgaacggc gcggccccga agcggggcga ccgggcgcgc tcaggcggct tcggcgggcg
    10021 gcgcgcacag cagcgggtcg agatcgagcg cggcgagcgt ttgcgcgtcg aggtcgatcc
    10081 agcacgcgac gaccatgcgc ccgtcgatct gctgcgcggg ccccgcccgg tgcgcgtgca
    10141 cgccgatccg gcggaacagg cgctccatgc tcagaaacgt cacgccgatc agttgcttcg
    10201 cgccaagccg cgcggcgcac tcgacgacgg cggcgagcat cggccgcacc gcccaggccg
    10261 ggttgccgcc cccggccgga tcctcggcgt tcgcggcgaa gcgcgacaat tcccagacgg
    10321 cggcggattg cggcaacggc atgtcttgcg cgaccagcgt cgggaacagt tccttcagca
    10381 gatacgggcg ggtcgtcggc agcagccggg cgcagccgca gatttccccg tcgtcgtcgc
    10441 gggcgaacac atagacggta tcgtcgcgat cgtactgatc ccgctcgaac ccttcgcttg
    10501 ccgacggcag tttccagccg agctgctcga cgaaaactcg gtgccgataa aggcccagat
    10561 cagccgccaa gtcgctcggc aggcgcccgt cgccatgaac gaaagttcgc atgtcgtcct
    10621 cgtgcgtgtg ctttggaatg ggcgcattac atcgcgcgct ccgaggacag gtaactgtta
    10681 acccttacag ggtcgggaaa gcggggttgg tggcgggggc ggggcgggtt ccgccggttt
    10741 tcgtcggtgt cggactgcaa agattcgata atttgcttgt caatccgcaa cgttcgagga
    10801 aaattagaca atatgcactg attgcgccga cgcgcgtcac tgcagggtgg gacccgcatg
    10861 cgcaaaatcg ccgcgacgaa gcatcgcggc ggtgacggcg gacggccagt tcagttgggc
    10921 gagccggcgc gacagtgcgg ccgaggtcgg atccatgccg atgtcgagcc cgttgccgtc
    10981 gacgcccatc acgttgctgc gcacgtcgcc ccatgcaatg acgaaggcgc ccgttgcgcc
    11041 gtcgatgtac cagtcccagc ccaccgtgag atgcgccgcg ccggcgctcg acggccgctc
    11101 ccactcggtg tagccggcga tgcgggcgtc gatgtcgctc gcacgtagtt cgacgagcag
    11161 tccggaatcg attccggacg atacgtgaac gagccgcagc tcggcgaacg cgtgcatcgg
    11221 aaggcgcacg tagccgtcgg tggaagagcc gcgaaagcgg tggagccatg gtgaattcat
    11281 gccgcggaat gtatcagccc gcgcgcgtgc tgaaacctag caagtatgac agcgtgaagc
    11341 tgctggagaa cgaatggaac tgcgctggca agacgcctat cttcaattta gcgccgcgga
    11401 gaacgagcag cagctcttcc aacagatcgc cgcgtatacg aagcggctcg gcttcgaata
    11461 ttgctgctat ggcatacgcg tgccgttgcc gatctcgaag ccggtcgtcg cgattttcga
    11521 tacctatccg aacggctgga tggagcgcta ccaggaaatg aactacctgg aggtcgatcc
    11581 gaccgtacgc gagggcgcgc tcagctcgaa catgatcgtc tggccggagg cgagcgcgag
    11641 cgacgcgacg acgctctgga gcgacgcgcg cgatcacggg ctggcggtcg gcgtcgcgca
    11701 gtcgagctgg gcctcgcgcg gggtgttcgg tctcctgacg atcgcgcggc acaccgaccg
    11761 cctgacgtcc gccgagatca accatctgac gttgcaggcg aactggctcg cgaacatgtc
    11821 gcactcgctg atgagccgtt ttctcgtgcc gaagctcgcg cccgaatcgg gcgtggcgct
    11881 cacgcaccgc gagcgggagg tgctgtgctg gacgggagag ggcaagaccg cgtgcgagat
    11941 cgggcagatc ctcagcatct ccgagcgcac ggtgaacttt cacgtcaaca acatcctcga
    12001 caagctcggc gcgacgaaca aggtgcaggc cgtcgtgaag gcgatcgcga tggggctcat
    12061 cgacgcgccg taagcattgc cgcgagcgcc gtcgcggccg cgcggcgctc actccatcaa
    12121 cggttccgct tccttcgcgg tccagctcac gctggagatg cttttctcca tgctcatccg
    12181 gctcgcgatc tgctcgagct tctgctgatc cttcgggtgc agcttcagcg tcgccgtcac
    12241 cttgatgcgc tcgggcgcat cggcttcgcg cggcacgtcc tcgctcgtca ggctctggaa
    12301 cgacagcggc ttcgcgtaca tcgagttcga cagcagcgtg cggatgtgca cttcgtccga
    12361 tgcgaggcag atcaccgtga tttgatattc gcgcacgaga tcggcgttcg acacgggcgt
    12421 cgcgttgatc gcctggctca cgccgcgcag cagcgtgttg gtgagcagca cgacgcccgt
    12481 gcccgcgagc gcgggcaggt agtggccggc gcccgagagc acgccgaccg cggccgagca
    12541 ccagagggtg gccgcggtgt tgatgccctg gatcgagcct ttgtcgcgca tgatgacgcc
    12601 gccgccgaga aagccgacgc cggagacgac atacgcggcg atctgcgtga cgccggggat
    12661 tccgttgccc gtgagtacgc cgagcgtgac gaacagacac gcgccgctcg cgacgagcgt
    12721 gatcgtgcgc aagccggccg tgcgctggcg gatctgccgt tcgaggccga tggcgacccc
    12781 gcaggcgaac gcggtgaaga ggcgaagtgc gaattcgaaa gtcatgggtg ttctgccgtg
    12841 ccgaatgcgc cgcgcgatgg gcgcggcggc gcacgcttgc cgggcgcgcg tgcattacgt
    12901 acgcgcgcgc cactttagcg cgcgaatcga tgcgattgtg tgaaacggga aatcgcacgc
    12961 gttcttcgat gaacgcgcgc ggcggcgaag cggccggcag gcgttcaggc gaagcggcgt
    13021 gcggacgttg tgctgctact gtccacgacg gttcctgaaa gaatggatgg cgggcattct
    13081 aggcgggacc cgccgtgtga gtcaacccgc gcggcggcgg tgaatgcgcg ggcgcggggc
    13141 gggatgcgtt tcgcgcaggg cacggcggct gcgcgaacgc gcggcggcgg tggcgtggga
    13201 gcggggcgtg cgccgtcgaa atgtcagcgc ggctcgacgg cgtatgtgaa ggcgggcgct
    13261 gctgttgctg tcgcgcatgc gttcccgatg gcgttcggcg ttcggcgttc ggcgttcagc
    13321 gttcggcgtt cggcgttcgg cgttcggcgt tcggcgttcg gcgttcggcg ttcggcgttc
    13381 agcgttcagc gttcagcgtt cagcgttcag cgttcagcgt tcagcgttca gcgttcagcg
    13441 ttcagcgttc agcgttcagc gtgacggacg ccggcgcgcg cgttcggttc ccttcgccgc
    13501 gcacgagccg cacgcgcgtg atttccgacg gcgcgccgag ccgtttcggc ggcccccagt
    13561 aaccggtgcc gcggctcgta tagacccaca ggccgttgag tcgcgcgagc ccggcggtga
    13621 acggctgctg caatcgcacg aagaaattcc acgggaaaaa ctggccgccg tgcgtgtgcc
    13681 cggacagttg cagcgtgaag cccgcatcgg ccgcggcggt tgcgctgcgc ggctggtgcg
    13741 cgagcagcac gcggatgcgc acgtcggcgg gcgcgccggc gagcgccgcg ctcgggtcgc
    13801 tccgatgcgc gggatcgaag tggcccgccg agtaatcggt gacgcccgcg atcacgagcc
    13861 ggccgtcgcc gtggtcgagc gtccgatgct cgttgagcag cacgtcgagg ccgaggcggc
    13921 ggaactcggc gatccactcg tcggcgcccg aatagtactc gtggttgccc gtcacgacga
    13981 atgcgccgtg gcgcgcgcgc agccgcccga gcggcgccgc atggccggcc agttgcgcga
    14041 ccgtgccgtc gacgacgtca cccgtcaccg cgacgagatc cggcgcgagc cggttgaccg
    14101 cgtcgacgat cgcctcgacg tagccgcgct tgatcgtcgg gccgacatgg atgtcgctga
    14161 tctgcacgat cgtgaagccg tcgagcgcgg cgggcagatc gtcgatcggc accgcgacgt
    14221 cgacgacgcg tgcgcggcgt cgcgcattga cgaagccgac gacgctcacc gcgagcgccg
    14281 cgagcggcac gccggccgcc gtctgtatcc gccactgcgc gagcgacacc gcgccgggcg
    14341 cgagcgcgtc gacggtgacg agcgaggcga gcagcacgtc gcgcgcgagc gtgagcacga
    14401 gcagcgacga gaagaagccc atcgcgagga ggccggccca ggcgacgcga tcgccgagcg
    14461 gctgccgctc gaacacgcgc gacagcatgc cgagcggaat cagcaggcac gacccgacga
    14521 gccacagcgc gcccgcgtag cgcgcggcgg gcgaggcgag ctcgggcagc agacggaagc
    14581 cgacgtacac gtgcagcagc acgccgatga tcgtcaggcg cagcagaaac gatgaaacgc
    14641 gtcgcatggg cggaaacggg ggaagtcggg agaggtggcg cggcgcgcga acgcgccgcc
    14701 gtcgcgcgct tattcgatgc gcgcgatttc gtcgaacgag aagcgggggc tgcgcgggaa
    14761 caggccggcg gcgtcgccgt agccgaggtt cacgaggaag ttcgacttga tcgacgtgcc
    14821 ggcgaagaac gccgcgtcga cggcagcctg atcgaagccc gacatcggcc cggcatcgag
    14881 gccgagcgcg cgcgcggcga cgatcagata cgcgccttgc agcgacgcat tgcgaaacgc
    14941 ggtcgcctcg atcagcgcgt cgttgccggc gaaccagctg cgcgcgtccg cgtgcgggaa
    15001 gagcttcggc aggtgatcgt ggaacgccat gtccatgccg acgatcacgg tgacgggcgc
    15061 ggccatcgtc ttcgcgagat tgccttcgga cagcgcgggc ttgagtttgg ccttcgcctc
    15121 gggcgacttc acgaacacga agcgcgcggg gctcgagttc gccgacgtcg ggccccactt
    15181 gacgagatcg atcagttcgc ggagcagcgc gtcgtcgacg ggcttcggct gccatgcgtt
    15241 gtgggtgcgc gcggtacgaa aaatttgatc gagagcggaa tcggaaagag tcatgtcggg
    15301 aatccgggtg agcgcgcaaa cgccgtggcg ttcgcgcggc tagaatttga acaggacggc
    15361 gcggatcgcg ggttgcggtt cgcgccattc cgcgatgata gccggatgcg gagattttga
    15421 ccgacgatgg acgatttgtt cgacgatctg ccgagacccg atgccgactg gcatccggac
    15481 tggctcgcgc ccgccgacgc cgaccgcttc catgcgcgcc tcgtcgacga ggtcgcgtgg
    15541 cgccaggaca cgatgcgcac gccgcgcggc ctgttgccgc tgccgcgcct gaccgcgtgg
    15601 cagggcgagc cggacgcgct ctacgtgtat tcgggcatcc gcaacgagcc ggcgccctgg
    15661 acgcccgccg tgctcgagct gaagcgaagg gtcgaggcgg cgagccgcgc gcgcttcaac
    15721 agcgtgctgc tgaaccgcta tcgcaacggc ttcgacagca tgggctggca tgcggacgac
    15781 gagccggagc tcggcgccga gccggtgatc gcgtcgctga gcctcggcgc gacgcgggtg
    15841 ttcgatctgc ggcacaacga gacgggcgtg acgcacgcgt atcgtctgac gaacggcagc
    15901 ctgctcgtga tgcgcgggcg cacccagcac gcatggcggc accgcgtgcc gaaggagccc
    15961 gcggtacggg gcgagcggat caacctgacg tttcgctggg tgagcgcgcc gcccgccgcc
    16021 gagcgccgcg cgaggccgcg ttcgcgcgga tgacgcgggc ccgcccgcgc gccgaaaccg
    16081 cgcggccttc ggatgatgtc gcgttatgat tcggtttctc tccgtccctt gcagccgaca
    16141 tggccaaaac cactacgacc gccgcgggta gacctgccgc cgacgccgca tcggccaagt
    16201 cgcgccgtgc cgcggccggc gcgcgccccg aacttgacgc ggccgacgac gaagtcgcgg
    16261 gcggcgcatc gtcgtacctc gttcccgggc tcgagcgcgg gctgcggatc ctgtccgaat
    16321 tttccgcgcg cgagccggtg ctgagcgcgc cggagctgtc caagcgcatc ggcattccgc
    16381 gcacgacgac gttccgcctg ctgcagacgc tcgaggcgct cggcttcatc gagcgcgcga
    16441 acggcgaccg ccatttccgg ctcggcatcg gcgtgctgcg gctcggtttc gaatatctga
    16501 attcgctcga attgaccgat ctcggcgcgc cggtgctcga gcgcctgcgc gacgcggccg
    16561 ggctgtcgac gcatctgctg atccgcgacc gccgcgacgt cgtgttcgtc gccaaggcgc
    16621 agagcaacgc gccgatgttc ggctcggtga aggtgcacgt gggcacgcgg ctgcccgcgc
    16681 acgcgaccgt gcacggccac gtgttgatgg gcgacctcac gcgcgacgcg atgcgccagc
    16741 tctatcccga gaagcgcctc gaggcgttca ccgaacacac gcccgcgacc gtcgacgaac
    16801 tgtacgagcg cgtgcgccat tacgcgcgtc tcggttacgc gctcagcgaa ggggcgttcg
    16861 agagcgggat ttcggcggtg acggcgccgg tgcgcgacca ttcgggctcg atcgtcgcgg
    16921 cgatcaccgc gacggtgccg cgctcggaaa ttggcgccgt cgacgaaaag gagcggctcg
    16981 tcgaactcgt gtgcggcgcg gccgtcgatt tgtcgcagcg gctgaactac cggccgctcg
    17041 acggcgatcc gaccgtcgcg catgcgcggc acaaggttgc gttgctctga cgacgtccgg
    17101 ccgcatcgag cggggcgagc ggggcgcaca tgcggcgtat tgcggcgcgc gccgcggcgg
    17161 ccgatgatgc cggcgccggg ggcggcatgg cgtaggcagc ggcgcgcgtc ggcggcccgg
    17221 cgggccgatc cccctttcat tgcatttgcc gccgcggaaa ggaaaaagcc tccgttttgc
    17281 gcggaggctt tttcgcattc gtgagcatcg ccgcgatgcg cgccgaagaa acgccacgtc
    17341 gcttgcgagc gccgctcggc acgcgccgtc gccaccgccg cgcgtgtgcg aaacgatgcg
    17401 ccgcgctcag aacgagtggt gaatccccgt caggacaatc acctgattcg ccgtgctcga
    17461 cgcgcccgcc gtgaagaacg cggccttcgc gttgccgctc gcgtgctcgt acagcacgtt
    17521 cacgtagagc tgcgtgcgct tggacagcga atacgtgtcg ccgagttcga actgggtcca
    17581 gcggcggccg gcgagcgtcg aagtcgccgc gccgcccgcg atcacgttga acggcgagct
    17641 ctggtagttc gcgccggcgt cgtagctctg gaacgtatcc gagtggccgt tcgcctgcag
    17701 tttcacgcgc gtgtaaaggc cgtgcacgag cagcgggccg aagcggtacg acaggcccgc
    17761 gcccatgttc tgcgccttct tcgcgacata gctcgcgacg ggcatgccct ggaacgtgcc
    17821 gcccggcccg gcgatgccgc cgacggtcgc catcgggaac gcctggtcgt gctcgttcga
    17881 atagacggcg gccgccttga acgggccgtt cgcgtagttc acgccgaagc tcatcgtgcg
    17941 gccggtcgag aagttcgtcg tgttgccgaa gccgagcatc gcgcccaccg tgaagcccgc
    18001 aaaggcgggc gagcggtact tgaccgagtt gttgaacggc acggtgctgg tgtccgcgag
    18061 ctggtcgagg ttgccgggat ggaacgcata ccagctctgc gcgaggaatg cgctcgacag
    18121 cgggtcgagc cagtcgaagt tgaacggcgt ctggtggccg agcgtcagcg cgccgagccg
    18181 gtcggaattc aggccgacga acgcctgacg gttccacatc gtgcccgccg ccgccatctg
    18241 gccgttgttc gtatagaagc cgttttcgag ctggaagatc gccttcagac cgccgcccag
    18301 atcctcgacg ccctttagcc cccatcgatc gggctgcgtg ttgccctgaa tcatcgacca
    18361 ctttgcgccg ccgccgacgt tgttcacgta cgcgacgccg gcgtcgaggc tgccgtacag
    18421 cgtgacgctg ctctgcgccc acgcgccggc ggcggcgagc gcgccgagta atgttgctac
    18481 cgcatgcttg accatctgat ctcctgacct ttgctccaaa tgacgcgggc ggtggccgcg
    18541 cgcgaaacga tcggccacgc gcgttcccac ggctgagttt ttggctttct tttgttccat
    18601 atatggaact gtgtgccttt agtggaatgg agtatagggg cggaaatcag cggaaacaaa
    18661 taaattttcg aatcgaagcg gcggccgcga ttcgtccgag gacatatcgc caacgctttg
    18721 aaagttcgag ggaaaacccg aaatttccgc ttcttgccgg ttccgcctgc attgccgggc
    18781 atcgagcgga aacgcggtct cggtattttc cctaggagcc tcggcttttt attttgatct
    18841 tcggatgacg ctcctataat caccatccat aaactgacgt tccgtatttg gaacaatcaa
    18901 gcgagtcgac ttgaaggaag ggtgtgagat gtctgaacaa tgggtttgcg ccggacacgc
    18961 cggcgcgctg tccgaggatt cgccgatcga gttcaagcgc accgacggcg tcgagatcgg
    19021 gatctaccgc gtcggcgacg acgtgtacgc gctcgagaac gtctgcccgc acgcgtatgc
    19081 gctgctcacg caaggcttcg tcgacgaggg cacggtcgag tgcccgctgc acgaggccgt
    19141 gttcgacatc aagacgggcc agtgcctgaa ggggccgggc ggccgcgcgc tgaagacgta
    19201 cgcggtgcgg ctcgccggcg aggaaatcca gatcaaggtg gaatgacatg aacgagacga
    19261 ccgtgaactt caatccgttg ctcatgccgt ggcgcgcgcc gcagccgaac aacgtcgcgg
    19321 gcaaggggca gatcgagatt cccgggcgga tgccgaatct cgtgtggcag acgcgcaagg
    19381 ccgagccgac gcagtacgag aacgatctcg gcgacgcgct cgagcgcgtg ttcgaaagcg
    19441 gcgcgaccga actcgcggag gtcgtcgcgg gcctgaaccg catcggcttt cgcgcgcccg
    19501 acggcgccga gtggaccgcc gagcgcttct gcgcggaact cgccgcgctc gccgaatgac
    19561 gcagccgccc tcaaacgctt ccggagcaaa cagatgacgt cttccgacca aacgaattcc
    19621 ggcaccgatc cggtgcgcgc gtatctcgac cgcggcatcc gcaactactg gtatcccgtc
    19681 gcgccgagct ggcaggtgtc gagcgcgccc gtcggcatca ttcggttgtc cgaacagatc
    19741 gtgttgtggc gcgatcggga gggcaacgtg cacgcgctcg aggatcgctg cccgcatcgc
    19801 ggcgcgcgcc tgtcgctcgg ctggaatctc ggcgatcgcg tcgcgtgctg gtatcacggc
    19861 gtcgaagtaa acggcggcgg taccgtgacg aaggtgccgg ccgtgtcgaa ctgtccgctc
    19921 gaagggcagg cctgcgtgaa gtcgtacccg gtcgaggagc gtgcgggcgc gatcttcctg
    19981 tggttcggcg acgacgcgca tcgcgagccc gcgccgctcg ttttgcccga cgaactcgtc
    20041 gcgccggagt acgcgcaatt cgtttgcgtg tcgaactgga cctgcaatta ccagtacgcg
    20101 atcgacaacg tgatggaccc gatgcacggc gcgtatctgc acgcgacatc gcattcgatg
    20161 gccgaaggcg acaagcaggc cgacatgcgc gtgcgcagga ccgagacggg cctgatgttc
    20221 gagaaggtca atcagcgcga cgtgaacttc gactgggtcg aactcggcga gacgggctgc
    20281 atctggctgc gcctcgcgat tccgtatcaa cgcaagttcg gccccggagg cagcttcggc
    20341 atcgtcggct tcgcgacgcc gatcgacgac gagcactgcc aagtctattt ctggcgcacc
    20401 cgcaaggttg ccggctggca gcgcgacgtg tggcgcttcc tgtatcggaa ccgcctcgag
    20461 gggctgcact gggcggtgct cgagcaagac cgctacgtgc tcgaaagcat ggcgccgaac
    20521 gcgcgcgatc acgaatacct gtatcagcac gacatcggcg tcacgcgcgt gcggcggatg
    20581 ctgcgccagc gcgcgcagga gcatctcgcc gc
//
