LOCUS       NZ_CP009477            21574 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Burkholderia pseudomallei MSHR2543 chromosome II, complete sequence.
ACCESSION   NZ_CP009477
VERSION     NZ_CP009477.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei MSHR2543
  ORGANISM  Burkholderia pseudomallei MSHR2543
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3205965)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.E.,
            Davenport,K.W., Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C.,
            Coyne,S.R., Broomall,S.M., Li,P.E., Teshima,H., Gibbons,H.S.,
            Palacios,G.F., Rosenzweig,C.N., Redden,C.L., Xu,Y., Minogue,T.D. and
            Chain,P.S.
  TITLE     Complete genome sequences for 59 burkholderia isolates, both
            pathogenic and near neighbor
  JOURNAL   Genome Announc 3 (2), e00159-15 (2015)
   PUBMED   25931592
  REMARK    Erratum:[Genome Announc. 2016 Apr 21;4(2):e00313-16. doi:
            10.1128/genomeA.00313-16. PMID: 27103731] Publication Status:
            Online-Only
REFERENCE   2  (bases 1 to 3205965)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.,
            Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C., Coyne,S.R.,
            Broomall,S.M., Li,P.-E., Teshima,H., Gibbons,H.S., Palacios,G.F.,
            Rosenzweig,C.N., McMurry,K., Redden,C.L., Xu,Y., Currie,B., Mayo,M.,
            Minogue,T.D. and Chain,P.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-SEP-2014
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; Allpaths v.
            44837; Phrap v. SPS - 4.24; HGAP v. 2.2.0
            Genome Coverage                   :: 463x
            Sequencing Technology             :: Illumina; PacBio, 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000959225.1-RS_2024_06_16
            Annotation Date                   :: 06/16/2024 14:42:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,715
            CDSs (total)                      :: 6,638
            Genes (coding)                    :: 6,472
            CDSs (with protein)               :: 6,472
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 166
            CDSs (without protein)            :: 166
            Pseudo Genes (ambiguous residues) :: 0 of 166
            Pseudo Genes (frameshifted)       :: 85 of 166
            Pseudo Genes (incomplete)         :: 110 of 166
            Pseudo Genes (internal stop)      :: 20 of 166
            Pseudo Genes (multiple problems)  :: 39 of 166
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:58:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1053142
            Orig. end                         :: 1074716
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009477.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The DNA was obtained from USAMRIID.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21574
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21574
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21574
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11574](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11574)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            299..1414
                     /locus_tag="BG16_RS04240"
                     /old_locus_tag="BG16_4577"
     CDS             299..1414
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900874.1"
                     /locus_tag="BG16_RS04240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4577"
                     /product="ATP-binding protein"
                     /protein_id="WP_004535157.1"
                     /transl_table=11
                     /translation="MNSTQAHRLSPFRYLKWRWLHFRRSWTDTRADRIPSWSRLYLRTY
                     LHLVGLVLVTVGGTIAVLCSALGPRTVWRALDALPGGALPLAAFVLAVPALAGYRWMRP
                     VWSDLVMVRARAIDFTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIATQRDLTNG
                     ISHELRTPLARVRFALESLREPGSAAEYQNAIDSIEQDVSELDELIDMSLTYARLEYSS
                     LQSNLEQTALVAWFDKQVADAALLYPSKAIEARVALPAELRVKMDKRLMSYAMRNLLRN
                     ASKHARGRISVGLRIRHGNIEIDVEDDGPGVPPDERERIFDAFVRLDRHTAGYGLGLAI
                     TRLVLQAHNGRVAVVDPLRLPGARFEMSWPV"
     misc_feature    323..325
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1751..3937)
                     /locus_tag="BG16_RS04245"
                     /old_locus_tag="BG16_4578"
     CDS             complement(1751..3937)
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201950.1"
                     /locus_tag="BG16_RS04245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4578"
                     /product="patatin-like phospholipase family protein"
                     /protein_id="WP_004557353.1"
                     /transl_table=11
                     /translation="MPDGGGPHRPAIGLVLSGGGARGYAHLGVLKVLEANRIPVDCIAA
                     TSMGAVVGGLYATGMTAQDMQRRLSQVNLADIAFDVTERSDLPQKKREDERLYIDSLTI
                     GFDSKGFKAPVGLVQGNRLQALLANWTAAVPTSQPFDRLPIPFRAIATDLQTGQKVVLD
                     HGSLPLAIRASMALPGLFSPAEIDGRALVDGGLVGNLPVDAARAMGADVVIAVDIGSPL
                     RPLDALASPADVMQQMIGILIRQNVAEQRKQLTANDILLQPDLGKQTFTDFQNANQAIA
                     AGEAAAVAALPRLARYALSPEQYEAYRAAHARPQQPIRITSIEIRTNGASVPKQIVRNA
                     LHVKPGDVYDPQAVSADLLSLTTSGNFENVTQQIINEGDEHRLVIDAQEKYWGPNFLLF
                     GLGMSSSSTDEGGFRLHLGYRRPWLTPSGLEFRADTTLGSDMQSVHVELRQPLSNKTGY
                     YVAPYADYKRRFANLYNGESDVKVTQYRIQTSRAGLDLGLPLARLGDFRIGLAYTHLSA
                     APSYSLLLDSWVDDDGNSLSFPSWYARQVSARARLVIDQLDDPLFPRKGYFAEFRAERS
                     LATSEDKFTDVYGKLMVAERFGRHSVSASVEAGKSFGGVNLSNPFGYTLGGFQHLSAYA
                     ADQLSGDALLYGQVTYMNQLATFNASPIKALYLGASAEVGNVWSLDPAFPSGPLKQSYT
                     FFTSLITSFGPVYVGMAFAPGGRRNIYFQLGRTY"
     gene            3936..4073
                     /locus_tag="BG16_RS42925"
     CDS             3936..4073
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BG16_RS42925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_175648201.1"
                     /transl_table=11
                     /translation="MQTRVSVAAGVGAAAVDAEAPAAAGVAAVGVVGAEGAPAPASGAV
                     "
     gene            4215..4556
                     /locus_tag="BG16_RS42930"
     CDS             4215..4556
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004545898.1"
                     /locus_tag="BG16_RS42930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_063840679.1"
                     /transl_table=11
                     /translation="MAAEAEDEARDEAEDEAEDEAEAEAEAEAATADEATRVGVAAGGS
                     VVEAGAPAALAAAVAADATVAVSAAAAGAGRPVAAQTNSRAATKPGTRKPARAEEASTV
                     IIVALVWSD"
     gene            4825..5889
                     /locus_tag="BG16_RS04250"
                     /old_locus_tag="BG16_4579"
     CDS             4825..5889
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009967944.1"
                     /locus_tag="BG16_RS04250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4579"
                     /product="rod shape-determining protein"
                     /protein_id="WP_004198787.1"
                     /transl_table=11
                     /translation="MAAPFLGRFFAHNVAVDPGTASTLIYVRNRGVVLNQPSVVCFRKR
                     GGPAERARVEAVGEQAKALLGRSPEHLEAVRPLRHGVVANYHAAEQMMRQFVGMSHARS
                     LFGRRVEFTICVPSNATAVEQRAIREAALAAGASRVSLISEPLAAALGAGLPVSEAVGS
                     MVVDIGGGTTEVAVIALGGIVYREAIRVGGDQFDAAIVNHVRNLYGVLLGEHTAEHVKK
                     TIGTASCRVPRESIHAIGRSVADGLPRTIELSNHDIADALAAPLNQVVSAVKSALENAP
                     PELITDIADRGLVLTGGGALLANLGKRLHDETGLAARVADDPLTCAVRGAGEAMGRGGF
                     DAGDEDAGDFGMNR"
     gene            complement(5941..6174)
                     /locus_tag="BG16_RS04255"
                     /old_locus_tag="BG16_4580"
     CDS             complement(5941..6174)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009923852.1"
                     /locus_tag="BG16_RS04255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4580"
                     /product="c-type cytochrome"
                     /protein_id="WP_038729912.1"
                     /transl_table=11
                     /translation="MTYVTYAACAACAACHGQNGQGAGTFPRLAGQHADYLRQQIDVFR
                     NGMRANAPVMSAVAHTLDGDPAKAVAAWLQSR"
     gene            6395..6985
                     /locus_tag="BG16_RS04260"
                     /old_locus_tag="BG16_4581"
     CDS             6395..6985
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004538973.1"
                     /locus_tag="BG16_RS04260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4581"
                     /product="HD domain-containing protein"
                     /protein_id="WP_004198788.1"
                     /transl_table=11
                     /translation="MDIQKIEARLEFLREAERLKSVLRSAHTSTGRAESTAEHSWRLCL
                     MAITLADELPGLDMLKVLKMCVIHDLGEALRGDVPAIRADAHPDKSAHERADLLTLTRM
                     LDAPLRDEILSLWDEYERAASQEAQAVKALDKLETILQHAQGENPPDFDYAFNLTYGSR
                     YTSAAPLFRAVREIVDAQTRSRIDARGEPPPAR"
     gene            7086..9407
                     /locus_tag="BG16_RS04265"
                     /old_locus_tag="BG16_4582"
     CDS             7086..9407
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009975753.1"
                     /locus_tag="BG16_RS04265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4582"
                     /product="amylo-alpha-1,6-glucosidase"
                     /protein_id="WP_004553254.1"
                     /transl_table=11
                     /translation="MPRQADPASPRAPQAAAPASSSARCAAPGAAPPQSAQPPQSPQSP
                     QPAPSTPAFIAPEPDAQKAVRGSQFVLKAGDAFVVSDALGDIAGRDDGLFVDDMRVLSQ
                     WRLTFGGRAPSLLSGATSADNASFTAHLTNRPLPPLGGRETPEGVIHIERMRVLADNVL
                     HEALTLTNYGTCDAEVPLSVSFGADFKDMFEVRGSRRERRGAVAPPCVEAGAVRLRYDG
                     LDAVERSVRIGFEPKPDTLAVDRADYTLTIAAQACVSLYLTVEARVGAAHAGGDAFARR
                     PCVATGRGALRKALADVHRAMRERRRTIARVHTSNPLFNAWLDRSLADLGLLTTSLETG
                     PYPYAGIPWFSTPFGRDAVITSLQMLWLQPSLARGVLRFLAEHQARETSAFRDAEPGKI
                     MHEFRKSEMAATGEVPFALYYGGVDTTPLFVVLAGAYLEHTGDESLIDELWPALERAAQ
                     WVSTVCERNPRGLLDYQRTSARGLANQGWKDSQDSVFHADGRFPSGPIALVEVQAYACA
                     AFDAMATFSRRRGHAADTVRYAQRAKRLREQVEALFWMPEAGFYGIAVDGHGELCRVLA
                     SNAAHLLAFGLPEQSRGESVARVLGSTLFRTGWGVRTLAAGQPRFNPMAYHNGSIWPHD
                     NALAARGLARYGDKRAVLDLLRALFEAAVSFDMRLPELFCGFPRRRGEPPTAYPVACLP
                     QAWAAGAPFMMLQACLGISVDAARGEVRVERPELPEGVDWLRVDDLRVGGDSVSLTFRR
                     VEGQVVAAAEPGGARVVAVL"
     gene            9503..9766
                     /locus_tag="BG16_RS04270"
                     /old_locus_tag="BG16_4583"
     CDS             9503..9766
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897849.1"
                     /locus_tag="BG16_RS04270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4583"
                     /product="hypothetical protein"
                     /protein_id="WP_004199309.1"
                     /transl_table=11
                     /translation="MTNQKPDDARPHDDEPKLEQLEAAVDHLHDSIQSQSIAAGAAKGI
                     LFSLIETLGALVGDPDLPEHARSGYEALRDKANELKANLENR"
     gene            complement(10001..10294)
                     /locus_tag="BG16_RS43820"
                     /old_locus_tag="BG16_4584"
     CDS             complement(10001..10294)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009981323.1"
                     /locus_tag="BG16_RS43820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4584"
                     /product="hypothetical protein"
                     /protein_id="WP_258007904.1"
                     /sec_met_domain="T1TS (E-value: 6.7e-09, bitscore: 32.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKEREAEEIHHLGISLMHHERISLRAAMRDMRALASAQVERFPA
                     GQAELLRFVAASGAPPEIAAAARHCAANMGNWISSVYWFHHESDRYGTARDF"
     gene            complement(10243..11574)
                     /locus_tag="BG16_RS43825"
     CDS             complement(10243..11574)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="BG16_RS43825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_258007903.1"
                     /sec_met_domain="T1TS (E-value: 6.2e-26, bitscore: 89.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHQPAGIARRQPRDFDGVERLLVELDRGGGAVANQMRGQRMHPLG
                     DRFDCGRHDRGSLASNGFIDRARRSRGHALSSRRTDSAGIDTRCKKIFGRAHPRRSARA
                     RRDPRAAGAPARARRDACRGAPRASRGIRSIAVRRRIDDHLRMDAARSNAASPHARRRR
                     PPCPPRPRPRPRPRRCRRLVGSSARRLVGSPARRLVGEACRIASIERSFERRFDPHRRA
                     LHAHCVRWIGEQSLAPAGSPPADLRALRYPDLVAGYYVGAPPAVLEAIAGLSVWFFVWD
                     DRHDEDARRLRRAAWARLRDALCAVLASPRARVADAEPIVGALSDCIVRIRARLGDAWN
                     RRFTGHLRQMIDAYDDEFRARLAARIPTRDAYMRLRERTFDCEAWLDCLELAAGRALPD
                     AVRAAPPYRLAGPARRSNSPRFTTISVRCARSAKPKKSTISAFR"
     misc_feature    complement(10450..10452)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11473..11892
                     /locus_tag="BG16_RS04285"
                     /old_locus_tag="BG16_4586"
     CDS             11473..11892
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011204436.1"
                     /locus_tag="BG16_RS04285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4586"
                     /product="VOC family protein"
                     /protein_id="WP_256719050.1"
                     /transl_table=11
                     /translation="MCDGAAAAIEFYKKAFDAVEISRLPSRDAGRLMHAAVRIGDSTLM
                     LVDEMGQCGALSPKALKGSPVFIHLYVPDVDAVIARAVEAGAKLTMPPADMFWGDRYGQ
                     LEDPFGHRWSVATHRQDLTPEQIREGMASCVPPAQ"
     misc_feature    complement(11976..11989)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.27"
                     /tool="antismash"
     gene            12201..12860
                     /locus_tag="BG16_RS04290"
                     /old_locus_tag="BG16_4587"
     CDS             12201..12860
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_process="GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1193: glutathione S-transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009981326.1"
                     /locus_tag="BG16_RS04290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4587"
                     /product="glutathione S-transferase family protein"
                     /protein_id="WP_004554867.1"
                     /sec_met_domain="GST_N_3 (E-value: 6.9e-15, bitscore: 52.6,
                     seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="GST_C (E-value: 2.4e-09, bitscore: 34.6,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLKFYGHPFSLYCQKVLIALYEYDVPFEWCLLAGDTPQASAEFA
                     ARWPLKHMPMLVDGDRTIVESTILIEYLGLRRPASVRLVPADAGVALDARMMDRFFDCY
                     VSTPVQKIVFDALRPQAERDARGVADARRMLDTSYAWLERTLDGRDWAAGGAFTLADCA
                     AAPSLFYADWAHPIDPALQRVTAYRERLLARPSFARAVDEARPYRHLFPLGAPERD"
     gene            12901..13611
                     /locus_tag="BG16_RS04295"
                     /old_locus_tag="BG16_4588"
     CDS             12901..13611
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004530131.1"
                     /locus_tag="BG16_RS04295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4588"
                     /product="DUF899 domain-containing protein"
                     /protein_id="WP_004530131.1"
                     /transl_table=11
                     /translation="MTERSMQTPAAELVKRNTTRWPNESEAYRRARDALLVEEIELRRH
                     VERVAALRRALPPGGEVTGGYRFEGERGPCDFAQLFGDRQTLVVYSYMFGPQRERPCPM
                     CTSLLGAWNGEARDLEQRVALAVVARSPLERLVAFKRERGWRDLKLYCDLDGRYSRDYH
                     AIGADGDEVPAINVFTRRDGTIRHFWSGEMGGWSADPGQDPRGAPDPMPLWTILDMTPE
                     GRGIDWYPSLDYPD"
     misc_feature    13537..13539
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13741..13754
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     gene            13766..13957
                     /locus_tag="BG16_RS40295"
     CDS             13766..13957
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BG16_RS40295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124517955.1"
                     /transl_table=11
                     /translation="MDQSLGARRREISTSLRTKTVENCRVENALWRIVAAGSLPADSAA
                     DGAREARGEPISAAMPHF"
     misc_feature    complement(14100..14118)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.97"
                     /tool="antismash"
     misc_feature    14103..14121
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.71"
                     /tool="antismash"
     gene            14125..14457
                     /locus_tag="BG16_RS41345"
     CDS             14125..14457
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BG16_RS41345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_154234858.1"
                     /transl_table=11
                     /translation="MSMSRGMREIKRDTGISADSAIRMCCRLFDAFGKGPADQGVECPM
                     LSLSTSLPTKIVEKAAAPARCKQAEKRRCALAAMAGRTARIERHGARPSAFVGRFRGLR
                     CRVPLD"
     gene            complement(15465..16844)
                     /locus_tag="BG16_RS04300"
                     /old_locus_tag="BG16_4589"
     CDS             complement(15465..16844)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004551455.1"
                     /locus_tag="BG16_RS04300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4589"
                     /product="ATP-binding protein"
                     /protein_id="WP_004194633.1"
                     /transl_table=11
                     /translation="MTGARGFARRLNASLRGRLLMWLLPAACVVGVLASTGTYWGALRE
                     LDDLLDDQMRSMSKQIQVDDAGKLSIEGRDRLAKRHPADYDSDDVLLQVWRGGKLEFTT
                     DPATQLPPPAAAGFVTLDAGGQRWHTYVRESAGTTIRVAQPRQARWEAIAGIAVHLLWP
                     VLSLLPLLAIGLWLGIGYGLRPLGAIAAGLKRRHANRLDPLDITTVPTEAQPLASEIND
                     LLARLDRSFTLQRHFIADAAHELRTPIMGLSIQTQLLQRTASADERARILAQIQAGTTR
                     LSHLAEQLLTLARLEPEARSAPFAELDLAALGRSVVAERARIAAAQHVDLGALGTAPVR
                     VAGNADTLRVLLNNLVDNAIRYAGAGARVDVDARIDAGGTPVLEVRDNGPGIPAADRER
                     VWERFYRGGGAQLVSASGSGLGLSIVKRIAEQHHADVSLEAGADGRGLTVTVRFGAARQ
                     A"
     gene            complement(16841..17503)
                     /locus_tag="BG16_RS04305"
                     /old_locus_tag="BG16_4590"
     CDS             complement(16841..17503)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194706.1"
                     /locus_tag="BG16_RS04305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4590"
                     /product="response regulator"
                     /protein_id="WP_004194706.1"
                     /transl_table=11
                     /translation="MRVLLVEDDPLIGSGLEQGLKQEGFAVDWAQNADAATLALRTTSY
                     GLLLLDLGLPDKDGLAVLAALRRRDDALPVIVVTARDALPDRIAGLDCGADDYLVKPFA
                     LEELLARIRAVNRRQAGRAQTVLAVGALRLDPARHQVWRGDEEVALSPKEFVLLHELMR
                     EPGAVISREQFEERLYSWGEEIESNAVQVHIHNLRKKLGHDTILTVRGVGYRIGDGA"
     gene            17664..18524
                     /locus_tag="BG16_RS04310"
                     /old_locus_tag="BG16_4591"
     CDS             17664..18524
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010108400.1"
                     /locus_tag="BG16_RS04310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4591"
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="WP_045587331.1"
                     /transl_table=11
                     /translation="MPADFDELASLIRAQFSELSPQFQVGAAFLLDHPDEVAVSSMRKV
                     AQRANVQPASLVRLAQQFGFPGWNELRDLFVARVRTRPQPLTQRARSLVKPNAKASLAA
                     DLLAAQRHNLEASAAQNARALTEAAKLIRKAAHVHVAGFRSCYPVAFGFVYGYRLFRPT
                     VSLLTGVAGSLDMELRTIAKNSVTVVVSFAPYSAEATRVAQAARAQGGRIVAITDSAVS
                     PIALHADAQLIFTHDSPSFFPSLVAAHALVETLVAQLLALEGGEAIAALEQAEAELHAK
                     GAYVV"
     misc_feature    18602..18615
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.43"
                     /tool="antismash"
     misc_feature    complement(18603..18616)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.02"
                     /tool="antismash"
     misc_feature    18619..18634
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.87"
                     /tool="antismash"
     misc_feature    complement(18629..18640)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.3"
                     /tool="antismash"
     misc_feature    complement(18782..18798)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.95"
                     /tool="antismash"
     misc_feature    complement(18783..18798)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(18784..18797)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.64"
                     /tool="antismash"
     misc_feature    18785..18798
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.78"
                     /tool="antismash"
     misc_feature    complement(18785..18800)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.91"
                     /tool="antismash"
     misc_feature    18812..18826
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.56"
                     /tool="antismash"
     misc_feature    complement(18862..18876)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.5"
                     /tool="antismash"
     gene            18910..19179
                     /locus_tag="BG16_RS04315"
                     /old_locus_tag="BG16_4592"
     CDS             18910..19179
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009914577.1"
                     /locus_tag="BG16_RS04315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4592"
                     /product="YodC family protein"
                     /protein_id="WP_004194594.1"
                     /transl_table=11
                     /translation="MTTYRDTHTTSFRIGDVVTLKTGGPRMTVTYAGPVVFDTGEWVIC
                     QWFDENGEFRQEMFPNETVVLEPRTISAGLARMRSLSVRGGMQA"
     gene            complement(19396..19722)
                     /locus_tag="BG16_RS04320"
                     /old_locus_tag="BG16_4593"
     CDS             complement(19396..19722)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006027681.1"
                     /locus_tag="BG16_RS04320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4593"
                     /product="superinfection immunity protein"
                     /protein_id="WP_004523737.1"
                     /transl_table=11
                     /translation="MQMEILIQIVGSVVAIALYFLPAIVADRRHRDDKLTIALFNALFG
                     WTGIGWLLTLYWSLQPNATDDFVSDVRLKRRALSMKTFSTGLVERVQRRIAAQEQWADK
                     QGTR"
     misc_feature    complement(19702..19717)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.89"
                     /tool="antismash"
     misc_feature    complement(19759..19774)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.26"
                     /tool="antismash"
     misc_feature    19782..19797
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.1"
                     /tool="antismash"
     gene            complement(19812..20279)
                     /locus_tag="BG16_RS04325"
                     /old_locus_tag="BG16_4594"
     CDS             complement(19812..20279)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010118182.1"
                     /locus_tag="BG16_RS04325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4594"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_004523738.1"
                     /transl_table=11
                     /translation="MSHVTEIPAADSAAAVAHFAASLAFETDCRDVHDALACGAPDFVL
                     LDVRGPEQYAAAHVPGALNLPHRKIIESKLSEFARDTCFVVYCAGPHCNGAARAALRLA
                     RLGRPVKLMLGGVTGWLDEGFALARGNGASRRQGGVRQRTAGNDPLRNRNN"
     misc_feature    complement(19830..19832)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20386..21342
                     /gene="ftrA"
                     /locus_tag="BG16_RS04330"
                     /old_locus_tag="BG16_4595"
     CDS             20386..21342
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="ftrA"
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009975767.1"
                     /locus_tag="BG16_RS04330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG16_4595"
                     /product="transcriptional regulator FtrA"
                     /protein_id="WP_004531591.1"
                     /transl_table=11
                     /translation="MHPHLVVALAYDRLCTFEFGCVVELFALPRPELGVDWYRFAVCAS
                     EPGPVRAAGGIKVQAPYRLALMDRADTIVIPGWRDPDETPPEPLLKKLRAAHRRGARLC
                     SICSGVFVLAAAGVLDGATVTTHWRYAERLQARYPALRVNPDALYVDAGRIVTSAGSAA
                     GLDMLMHLVRRDHGSAIANRVAQRLVLPPHRDGGQAQFVPRPLPSVGGDRLAKLIDWMR
                     AHAGQPHTLASLAARAAMSPRTLQRQFRDATGLGPYEWLIRERVGLAKEMIERDPALPV
                     ARVAALAGFGSEESLRRHFRRIAATSPAAYRRSFDAG"
ORIGIN
        1 tcgtggtgcg aaatcgcgcg cgccgcgtcg gccacggcga acgcctgtcc cgtgccgggc
       61 ggcgtcacgt ggcgcgggct tcgcgatgcg gtgcggcggc gcatggcgaa gccgctcggc
      121 gtgcgtcgcg gttttactgg acgaaacgcc gcgcccgctc atgtgccgcg cgcaggccgg
      181 ccgcggacgc cggcgctgat gccgatgccc gccgccgatc gccgccgatc gccgccggtc
      241 cggccggttt ccgcccgctg accgacggcg ccgctttccc gacattcgcg atccgaacat
      301 gaacagcacg caagcgcacc gattatcccc gttccgctat ctcaaatggc gctggctgca
      361 tttccgccgc tcgtggacgg acacgcgcgc cgaccggatt ccgagctggt cgcgccttta
      421 tctgcggacc tatctgcacc ttgtcggcct cgtgctggtg acggtcggcg ggacgatcgc
      481 cgtgctttgc tcggcgctcg gtccgcgcac ggtgtggcgc gcgctcgacg cgctgccggg
      541 cggcgcgctg ccgctcgccg cgttcgtgct cgcggtgccg gcgctcgccg gctatcgatg
      601 gatgcggccc gtctggtcgg atctcgtgat ggtgcgcgcg cgcgcgatcg atttcacggg
      661 cgggcgcttc aacacgcgcg cgcgcgaatc gcgcagcgtg atcatcgggc cgctcgcgcg
      721 cacgctgaac gcgctcgcga tgcgcatgga gcgcctgatc gccacgcagc gcgacctgac
      781 caacggcatt tcgcacgagc tgcgcacgcc gctcgcgcgc gtgcgcttcg cgctcgagag
      841 cctgcgcgag ccgggctcgg ccgccgagta tcagaacgcg atcgacagca tcgagcagga
      901 cgtgtccgag ctcgacgaac tgatcgacat gagcctcacg tacgcgcggc tcgaatacag
      961 ctcgctgcag tcgaatctcg agcagacggc gcttgtcgcg tggttcgaca agcaggtcgc
     1021 cgacgccgcg ctgctgtatc cgagcaaggc gatcgaagcg cgcgtcgcgt tgcccgccga
     1081 gctgcgtgtg aagatggaca agcggctgat gtcgtatgcg atgcgcaacc tgttgcgcaa
     1141 cgcgagcaag catgcgcgcg ggcggatctc ggtcgggttg cggatacgcc acggcaacat
     1201 cgagatcgac gtcgaggacg acgggcccgg cgtgccgccc gacgagcgcg agcggatctt
     1261 cgacgcattc gtgcggctcg atcgccatac ggcgggctac gggttggggc tcgcgatcac
     1321 gcggctggtg ctgcaggcgc ataacgggcg cgtcgccgtc gtcgatccgc tgcggttgcc
     1381 gggcgcgcgt ttcgagatga gctggccggt gtgatgcgcg gcgggaaggc gcgagcgcgg
     1441 gcgcgccgcg ggcggcccgc acgcgcgtct ggtcacggct ggcggtccgc gccgtcttct
     1501 cgatccatgc cccgcggcca tgcttgtgac tcgcgcctcg cagccgcgcc gccgggctgc
     1561 ggcgatggcg gtctggcctg cgcgctcttc gtcgcggcat ggtgcggtct cgcatcgagc
     1621 aagcgtcgtc gagccggccg gcgcgttcgt ttccttgaat cagttcgctg catgcggacg
     1681 cccgctcgag cgtccgttac ttgccgtgtc cggaaacggc ggcgccaggg caccatccac
     1741 ggtgcgcgga tcaatacgtg cggccgagct ggaagtagat gttgcgccgc ccgccgggtg
     1801 cgaacgccat accgacgtac acgggcccga acgatgtgat caggctggtg aagaacgtgt
     1861 agctctgctt gagcggaccg ctcggaaacg ccgggtcgag cgaccataca ttaccgactt
     1921 ccgcgctcgc gccgaggtag agcgccttga tcggagacgc attgaacgtc gccagctgat
     1981 tcatgtaggt gacctgtcca tagagaagcg catcgccgct caactggtcg gccgcgtacg
     2041 ccgatagatg ctggaagccg ccgagcgtgt agccgaacgg attgctgaga ttcacgccgc
     2101 cgaagctctt gcccgcctca acgctcgcgc tcacgctgtg ccggccgaag cgctcggcga
     2161 ccatcaactt gccgtagacg tcggtgaact tgtcctcgct cgtggcgagc gagcgttcgg
     2221 cgcggaattc cgcgaagtaa cccttgcgcg ggaagagcgg atcgtcgagc tggtcgatga
     2281 cgagccgggc gcgcgcgctg acctgccgtg cgtaccagga tgggaaggac agcgagttgc
     2341 cgtcgtcgtc gacccagctg tccagcagga ggctgtatga gggggcggcc gaaaggtgcg
     2401 tataggcgag gccgatccgg aaatccccga gccgcgcaag cggcagcccg agatcgagcc
     2461 ctgcacgtga ggtctggatc cggtattgcg tgaccttgac gtcgctttcc ccattgtaga
     2521 ggttcgcgaa ccgccgcttg tagtccgcgt acggcgcgac gtagtagccg gtcttgttcg
     2581 acagcggctg gcgcaactcg acgtgcaccg actgcatgtc gctgccgagc gtcgtatccg
     2641 cgcggaattc gaggccggac ggcgtgagcc agggccgccg gtagcccaga tgcagccgga
     2701 agccgccttc gtcggtggaa ctgctcgaca tccccagccc gaacagcagg aagttcggcc
     2761 cccagtactt ctcctgcgcg tcgatcacga gccggtgctc gtcgccttcg ttgatgatct
     2821 gctgcgtgac gttctcgaaa ttgccgctcg tcgtgagcga cagcagatcg gcgctgaccg
     2881 cctgcggatc gtagacgtcg cccggcttca cgtgcagcgc gttgcgcacg atctgcttgg
     2941 gcaccgacgc gccgttggtg cggatctcga tcgacgtgat gcgaatcggc tgctgcgggc
     3001 gcgcgtgggc ggcccgatac gcttcgtatt gctcgggcga cagcgcgtag cgcgcgagcc
     3061 gcggcagcgc ggcgacggcg gcggcctcgc ccgcggcgat cgcctggttc gcgttctgaa
     3121 aatcggtgaa cgtctgcttg ccgaggtccg gctgcagcag gatgtcgttc gccgtcagtt
     3181 gcttgcgctg ctcggcgacg ttctgccgga tcaggatgcc gatcatctgc tgcatcacgt
     3241 cggcgggcga cgctagcgcg tccagcgggc gcagcggcga gccgatgtcg accgcgatca
     3301 cgacgtccgc gcccatcgcg cgcgcggcgt cgacgggcag gttgccgacg agcccgccgt
     3361 ccacgagcgc gcggccgtcg atctcggcgg gcgagaacag gcccggcagc gccatgctcg
     3421 cgcggatcgc gagcggcagc gagccgtgat cgagcaccac cttctggccg gtctgcagat
     3481 cggtcgcgat cgctcggaac gggatcggca gccggtcgaa cggctggctc gtcggcacgg
     3541 cggcggtcca gttcgcgagg agcgcctgca gccggttgcc ctgcacgagc ccgacgggcg
     3601 ccttgaagcc cttcgaatcg aagccgatcg tcaggctgtc gatatagagg cgttcgtcct
     3661 cgcgcttctt ctgcggcagg tccgagcgct cggtcacgtc gaacgcgatg tcggcgaggt
     3721 tcacttgcga cagccgccgc tgcatgtcct gcgcggtcat gccggtcgcg tacaggccgc
     3781 cgacgaccgc gcccatgctc gtcgcggcga tgcagtcgac cggaatccgg ttcgcttcca
     3841 gcaccttcag cacgcccaga tgcgcgtagc cccgcgcgcc gccgcccgac agcacgaggc
     3901 cgatcgccgg ccggtgcggg ccgccgccgt ccggcatgca aacgagggtg tccgtcgcgg
     3961 ccggcgtcgg cgcggctgcc gtggacgccg aggcgcctgc ggcggccggc gtggcggcgg
     4021 tgggcgtcgt cggcgccgag ggcgcgcccg cgcccgcgtc gggcgcggtg tgaggggcgt
     4081 gggggccgtg ggcggcggcg gtcccggcga cgttcgatcc gctattcgag acggcattcg
     4141 agacggagct cgaatccggc gcgtcggcgc gccgggcggc ggtccacgac cacgcggccg
     4201 cagcgttcgc gggcgtggcg gccgaagcgg aggacgaggc gagggacgag gcggaggacg
     4261 aagcggagga cgaagcggag gccgaggcgg aggccgaagc ggccacggcc gacgaggcga
     4321 cgcgcgtcgg cgttgcggcg ggcgggagcg ttgtcgaagc cggcgcaccc gcagcgcttg
     4381 cggcggcggt cgcggcggac gccacggttg cggtatcggc cgcggcggcg ggtgcgggcc
     4441 gtcccgtcgc ggcgcagacg aacagcaggg cggccacgaa gccgggaacg cgaaagcccg
     4501 cacgggcgga agaggcgagc accgtcatta tcgttgcttt ggtgtggtcg gactgaaacg
     4561 gtcgggagcg ccgatccgga accggcaaaa gcgagagagt accgcttttg tcgggccgag
     4621 accacgcgtt gccgcgattc gcgccggccg ggcagtgcaa agcgacctgt cgcgctatag
     4681 aaaattcatg aaatctccta aagtattcag gcatcctgcc gctaagcgac tgagtggatt
     4741 gtgctcgtcg ccggcaaccg gcccgggggg cggccggcga cgcatccgcg gaacccttcc
     4801 acccgtttca atagaggctt cacgatggcg gcaccctttc ttggaaggtt ttttgcgcac
     4861 aacgtcgcgg tcgatcccgg cacggcgagc acgctgatct acgtccgcaa tcgcggcgtc
     4921 gtgctgaacc agccgtcggt cgtctgcttc cgcaagcggg gcggcccggc cgagcgggcg
     4981 cgcgtcgagg cggtcggcga gcaggcgaag gcgctcctcg gccgctcgcc cgagcatctg
     5041 gaagccgtca ggccgctcag gcacggcgtc gtcgcgaact atcacgcggc cgagcagatg
     5101 atgcggcagt tcgtcggcat gtcgcatgcg cgctcgctgt tcggccggcg cgtcgagttc
     5161 acgatctgcg tgccgtcgaa cgcgacggcg gtcgagcagc gcgcgatccg cgaagcggcg
     5221 ctcgcggcgg gcgcctcacg cgtgagcctg atcagcgagc cgctcgcggc cgcgctcggc
     5281 gcggggctgc cggtgtcgga ggcggtcggc tcgatggtgg tcgacatcgg cggcggtacg
     5341 accgaggtcg cggtgatcgc gcttggcggc atcgtctatc gcgaggcgat tcgcgtcggc
     5401 ggcgaccagt tcgacgcggc gatcgtcaat cacgtgcgga acctgtacgg cgtgctgctc
     5461 ggcgaacaca cggccgagca cgtgaagaag acgatcggca ccgcgagctg ccgggtgccg
     5521 cgcgaatcga tccacgcaat cgggcgcagc gtcgcggacg gcctgccgcg caccatcgag
     5581 ctcagcaatc atgacatcgc cgatgcgctc gccgcgccgc tgaaccaggt ggtgagcgcg
     5641 gtgaagagcg cgctcgagaa cgcgccgccc gagctgatca ccgacatcgc ggatcgcggc
     5701 ctcgtgctca cgggcggcgg cgcgctgctc gcgaacctcg gcaagcggct tcacgacgag
     5761 acggggctcg ccgcgcgggt cgccgacgat ccgctcacct gcgcggtgcg cggcgccggc
     5821 gaggcgatgg ggcggggcgg gttcgacgca ggcgacgagg acgcgggtga tttcggcatg
     5881 aatcgctgag ccgcgcgcgc cgccgagcgg ccgtgcggcc gtgcgcgcgc gtcgcgatcg
     5941 ctagcgcgat tgcagccacg ccgcgacggc cttcgccggg tcgccatcga gcgtatgcgc
     6001 gacggcgctc atcaccggcg cgttcgcgcg catgccgttc ctgaagacat cgatctgctg
     6061 ccgcagataa tcggcgtgct gtcccgcgag ccgcgggaac gtgcccgcgc cttggccgtt
     6121 ttgcccgtgg cacgccgcgc acgccgcgca cgccgcgtat gtcacgtatg tcatgtatgt
     6181 cgcccatgtc gccgcacatg ccgagccggg cgcataactt atgcgtggac gatacgccgg
     6241 cgcaccgcgt agactcgccg catcgaaccc ccgaaccacc gtgcgcggcc tatcgcgcgg
     6301 ctcgcggcga gacgcgcgcc cggcgtgcga gccgggtgcg caaccacgtc cgccgcgccc
     6361 cgatcgtccg ccgtcccgat gccgtcatat cgacatggac attcaaaaga tcgaagcgag
     6421 gcttgagttc ctgcgcgaag cggagcgcct gaagagcgtg ctgaggagcg cgcacacgtc
     6481 gacgggccgc gccgagagca cggccgagca cagctggcgg ctgtgcctga tggcgatcac
     6541 gctcgccgac gaactgccgg ggctcgacat gctcaaggtg ctgaagatgt gcgtgattca
     6601 cgatctcggc gaggcgctgc gcggcgacgt gccggcgatc cgcgccgacg cgcatcccga
     6661 caagagcgcg cacgagcgcg ccgatctgct gacgctcacg cgcatgctcg atgcgccgct
     6721 gcgcgacgaa atcctgtcgc tgtgggacga atacgagcgc gcggcgtcgc aggaggcgca
     6781 ggcggtgaag gcgctcgaca agctggaaac gatcctgcag cacgcccagg gagagaaccc
     6841 gcccgatttc gactacgcgt tcaacctcac gtacggcagc cgctacacga gcgcggcgcc
     6901 gctgtttcgc gcagtgcgcg agatcgtcga cgcgcagacc cgaagccgga tcgacgcgcg
     6961 gggcgagccg ccgccggcgc gctagccggc cggcgcgcac gcggctgcgc gcggcgcgca
     7021 ttctgtccta tcctgtgcgg aaaacgcggc gcacccggcg cgtcgcgccc agcccaggag
     7081 ttccgatgcc gaggcaagcc gaccccgctt ccccgcgcgc gccgcaagcc gccgcgcccg
     7141 cttcttcatc cgcgcgttgc gccgcgcccg gcgcggcgcc gccgcaatcg gcacaaccgc
     7201 cgcaatcgcc gcaatcgccg caaccggccc cgtccacgcc cgcgttcatc gcgcccgagc
     7261 ccgatgcgca gaaggccgtg cgcggcagcc agttcgtgct gaaggcgggc gacgcgttcg
     7321 tcgtgagcga cgcgctcggc gacatcgccg ggcgcgacga cggcctcttc gtcgacgaca
     7381 tgcgcgtgct gtcgcaatgg cggctcacgt tcggcggccg cgcgccgtcg ctgctgtcgg
     7441 gggcgacgag cgcggacaac gcgtcgttca ccgcgcacct gacgaaccgt ccgctgccgc
     7501 cgctcggcgg ccgcgagacg cccgagggcg tgatccacat cgagcggatg cgcgtgcttg
     7561 ccgacaatgt gcttcacgag gcgctcacgc tgacgaacta cggcacgtgc gacgccgagg
     7621 tgccgctgtc ggtgtcgttc ggcgcggact tcaaggacat gttcgaagtg cgcggctcgc
     7681 ggcgcgagcg gcgtggcgcg gtcgcgccgc cgtgcgtcga ggcgggcgcg gtcaggctgc
     7741 gctacgacgg gctcgacgcg gtcgagcgca gcgtgcggat cggcttcgag ccgaagcccg
     7801 acacgctcgc cgtcgatcgc gccgactaca cgctgacgat cgccgcgcag gcgtgcgtgt
     7861 cgctgtatct gacggtcgag gcgcgcgtgg gcgccgcgca cgcgggcggc gacgcgttcg
     7921 cgcggcggcc gtgcgtcgcg accgggcgcg gcgcgctgcg caaggcgctg gccgacgtgc
     7981 accgcgcgat gcgcgagcgg cgccgcacga tcgcgcgcgt gcacacgagc aatccgcttt
     8041 tcaacgcgtg gctcgaccgc tcgctcgcgg acctgggcct gctcacgacg tcgctcgaaa
     8101 ccggcccgta cccgtacgcg ggcattccgt ggttctcgac gccgttcggc cgcgacgcgg
     8161 tgatcacgtc gctgcagatg ctgtggctgc agccgtcgct cgcgcgcggc gtgctgcgct
     8221 ttctcgccga gcatcaggcg cgcgagacat cggcgtttcg cgacgcggag ccgggcaaga
     8281 tcatgcacga gttccgcaag agcgagatgg cggccacggg cgaagtgccg ttcgcgctgt
     8341 actacggcgg cgtcgatacc acgccgttgt tcgtcgtgct cgcgggcgcg tatctcgagc
     8401 acaccggcga cgaatcgctg atcgacgagc tgtggcccgc gctcgagcgc gccgcgcagt
     8461 gggtgagcac cgtgtgcgag cgcaacccgc gcgggctgct cgactatcag cgcacctccg
     8521 cgcgcgggct cgccaaccag ggctggaagg acagccagga ttcggtgttc cacgcggacg
     8581 gccgcttccc gagcgggccg atcgcgctcg tcgaagtgca ggcctacgcg tgcgcggcgt
     8641 tcgacgcaat ggcgacgttc tcgcgccggc gcggccacgc ggccgacacc gtgcgctacg
     8701 cgcagcgcgc gaagcggctg cgcgagcagg tcgaggcgtt gttctggatg cccgaggcgg
     8761 gcttctacgg catcgcggtg gacggccacg gcgagctgtg ccgcgtgctc gcgtcgaacg
     8821 ccgcgcacct gctcgcgttc ggcctgcccg agcagagccg cggcgaatcg gtcgcgcgcg
     8881 tgctcggctc gacgctgttt cgcaccggct ggggcgtgcg cacgctcgcg gccggccagc
     8941 cgcgcttcaa tccgatggcg tatcacaacg gctcgatctg gccgcacgac aacgcgctcg
     9001 ccgcgcgcgg cctcgcgcgc tacggcgaca agcgcgcggt gctcgatctg ttgcgcgcgc
     9061 tgttcgaggc ggccgtgagc ttcgacatgc ggctgcccga gctcttctgc ggcttcccgc
     9121 gccggcgcgg cgagccgcca acggcgtatc cggtcgcgtg cctgccgcag gcgtgggcgg
     9181 cgggcgcgcc gttcatgatg ctgcaggctt gcctcggcat ctcggtcgac gcggcgcgcg
     9241 gcgaggtgcg cgtcgagcgg cccgagctgc cggaaggcgt cgattggctg cgcgtcgacg
     9301 atctgcgcgt cggcggcgac agcgtgtcgc tcacgttccg gcgcgtcgag gggcaggtgg
     9361 tcgcggcggc cgagccgggc ggcgcgcgcg tcgtcgcggt gctgtaaaga ttgcgcccgc
     9421 tcgcgtcggg cgcgcgcggc gcgccataca atgacggcat cgatcaacga ttcgcaacga
     9481 accgatatcg gaggccctca ccatgacgaa ccagaagccg gacgacgccc gcccgcacga
     9541 cgacgagccg aagctcgagc agctcgaggc ggccgtcgac catctgcacg actcgatcca
     9601 gtcgcagagc atcgcggccg gcgcggcgaa gggcatcctg ttcagcctga tcgagacgct
     9661 cggcgcgctc gtcggcgatc cggacctgcc ggagcacgcg cgctccggct acgaagcgct
     9721 gcgcgacaag gcgaacgagc tgaaggcgaa tctcgagaat cgctgacgcg gcgcgctgcc
     9781 cgcccgttct ttgcatcggc gcggaaagcg ccgtggtttc aacggcttgg cgcgcgcgtg
     9841 cgcaggatat ccacatgttt gtcgacagaa actgttgata accggcgcgc gcggcggggc
     9901 gggggggcgg tccgtcgacg cgcggagcct cgcggccgcc gcgaccgtgc gccgtcgtcg
     9961 gcgcgggtgg gccgcgcaca tcgccgacgt ccggccgtca tcaaaagtcg cgcgcggtgc
    10021 cgtaacggtc cgattcgtgg tggaaccagt agaccgacga gatccagttg cccatgttcg
    10081 ccgcgcagtg gcgggccgcc gcggcgatct cgggcggtgc cccgctcgcg gcgacgaagc
    10141 gcagcagctc ggcctggccg gccgggaagc gctcgacctg cgcgctcgcc agcgcgcgca
    10201 tatcgcgcat cgcggcccgc agcgagatcc gctcgtgatg catcaacgaa atgccgagat
    10261 ggtggatttc ttcggcttcg cgctccttgc gcagcgaaca gagatcgttg taaagcgcgg
    10321 cgaattgctg cgacgcgcgg gaccggcgag ccgatacggc ggcgcggcgc gcaccgcgtc
    10381 gggtagcgcg cggccggccg cgagttcgag gcagtcgagc caggcttcac agtcgaacgt
    10441 gcgttcgcgt aaccgcatgt acgcgtcgcg cgtcgggatg cgcgccgcca ggcgcgcgcg
    10501 gaattcgtcg tcgtaggcgt cgatcatctg ccgcagatgg ccggtgaagc gccggttcca
    10561 ggcgtcgcca agccgcgcgc ggatccgcac gatgcaatcg gacagcgcgc cgacgatcgg
    10621 ctccgcgtcg gcgacgcgcg cacgcggcga agcgagcacc gcgcacagcg cgtcgcgcag
    10681 gcgcgcccac gcggcgcggc gcaaccgccg cgcgtcctcg tcgtgccggt cgtcccagac
    10741 gaagaaccag accgacagac cggcgatcgc ttcgagcacg gccggcggcg cgccgacgta
    10801 atagccggcg acgaggtccg gatagcggag cgcgcgcaag tcggccggcg gcgatccggc
    10861 gggcgcgagc gactgctcgc cgatccatcg gacgcaatgc gcgtgcagcg cgcgccggtg
    10921 cggatcgaaa cggcgctcaa acgaacgttc gatcgaggca atgcggcacg cttcgccgac
    10981 gagccggcga gccggcgagc cgacgagccg acgagccgac gagccgacga gccggcggca
    11041 tcggcgcggg cgcgggcgcg ggcgcgggcg tggcgggcat ggcggcctcc ttcggcgggc
    11101 gtgcggcgat gcagcgttcg aacgcgccgc gtccatgcga agatggtcgt cgatcctgcg
    11161 ccgcacggct atcgatcgaa tgccccgcga cgcacgcggc gctccccggc aggcgtcgcg
    11221 ccgcgcacgg gcgggtgcgc cggcggctcg cggatcacgc ctcgcgcgcg ccgagcggcg
    11281 cgggtgggcg cggccaaaaa ttttcttgca acgcgtgtcg attccggcgg aatccgttcg
    11341 tcgtgacgat agagcgtgcc cgcgcgagcg gcgcgctcga tcgatgaacc cattcgaagc
    11401 caaggagccg cgatcatgcc taccgcagtc aaaccgatcc ccgaggggat gcattcgctg
    11461 acccctcatc tgatttgcga cggcgccgcc gccgcgatcg agttctacaa gaaggcgttc
    11521 gacgccgtcg aaatctcgcg gttgccttcg cgcgatgccg gccggctgat gcatgcggcc
    11581 gtcaggatcg gcgattcgac gctgatgctc gtcgacgaga tggggcagtg cggcgcgttg
    11641 agccccaagg cactgaaggg ctcgcccgtg ttcatccacc tgtacgtgcc ggacgtcgac
    11701 gcggtgatcg cgcgcgcggt ggaagcgggc gcgaagctga cgatgccgcc cgccgacatg
    11761 ttctggggcg atcgctacgg ccagctcgag gatccgttcg ggcatcgctg gtcggtggcg
    11821 acgcaccggc aggacttgac gcccgagcag attcgcgaag ggatggcgag ctgcgtgccg
    11881 cccgcgcagt gaccgcgcgg cgggcgaggg gctcgccgcg tgcaggcgcg cggcgcatgt
    11941 gtgtgcgtat gtgcatgtat gcgtgtgcgt acgtgtgcgt gcgcatgcgc gccccggcgc
    12001 gcgccgtgcg tgcggtgcgc gtagcgggcg cggcgcgcat gcgccggcgg tcggcaatgg
    12061 ggcggcgcgc gatggtgagg cgtggcggag gtcgccgccc gtcgtccggg cggccgccca
    12121 tcgcgtgcga accggcgcgc gcggccgtgg cttgcggcgt gcgcgtgtcg cgcgcgccgc
    12181 gtcaatcgag gagaaacaca atgagcctga agttctacgg gcatccgttt tcgctgtatt
    12241 gccagaaggt gctgatcgcg ctgtacgagt acgacgtgcc gttcgaatgg tgcctgctcg
    12301 cgggcgacac gccgcaggcg agcgccgagt tcgctgcgcg atggcccctc aagcacatgc
    12361 cgatgctcgt cgacggcgat cgcacgatcg tcgagtcgac gattctcatc gagtatctcg
    12421 ggctgcgccg ccccgcgtcc gtgcggctcg tgcccgccga tgccggcgtg gcgctcgacg
    12481 cgcggatgat ggaccgcttc ttcgactgct acgtatcgac gccggtgcag aagatcgtgt
    12541 tcgacgcgct gcgcccgcaa gccgagcgcg atgcgcgcgg cgtcgccgat gcgcggcgca
    12601 tgctcgacac gtcgtacgcg tggctcgagc gcacgctcga cgggcgcgac tgggccgcgg
    12661 gcggcgcgtt caccctggcc gattgcgcgg ccgcgccttc gctgttctat gcggactggg
    12721 cgcatccgat cgatccggcg ctgcagcgcg tgaccgcata tcgcgagcgg ctgctcgcgc
    12781 ggccgtcgtt cgcgcgggca gtcgacgaag cgcgcccgta ccggcatctc tttccgctcg
    12841 gcgcacccga gcgggactag cgcaaacggg ccctgaccgt tcgatcgaca ggagacggac
    12901 atgacagaac gttcgatgca gacaccggcc gccgagctcg tgaaacgcaa cacgacgcga
    12961 tggccgaacg aaagcgaggc ctatcgccgc gcgcgcgacg cgctgctcgt cgaggagatc
    13021 gagctgcgcc ggcacgtcga gcgggtggcc gcgttgcggc gcgcgctgcc gccgggcggc
    13081 gaggtgacgg gcggctaccg cttcgagggc gagcgcggcc cgtgcgattt cgcgcagctg
    13141 ttcggcgaca ggcaaacgct cgtcgtctac agctacatgt tcgggccgca gcgcgagcgg
    13201 ccttgcccga tgtgcacgtc gctgctcggc gcgtggaacg gcgaggcgcg cgacctcgag
    13261 cagcgcgtcg cgctcgcggt cgtcgcgcgc tcgccgctcg agcggctcgt cgcgttcaag
    13321 cgcgagcgag gctggcgcga cctgaagctg tattgcgatc tcgacggccg ctacagccgc
    13381 gactatcacg cgatcggcgc cgacggcgac gaagtgccgg cgatcaacgt gttcacgcgc
    13441 cgcgacggta cgatccgcca cttctggagc ggcgagatgg gcggctggag cgccgacccc
    13501 gggcaggacc cgcgcggcgc acccgatccg atgccgttat ggacgatcct cgacatgacg
    13561 cccgaggggc gcggcatcga ctggtatccg tcgctcgact atccggattg acggcggtgc
    13621 gccgcgcgac gccggcacgg gcatgtgcga cggtgccggc atgcgcccgt ataggcgctc
    13681 gcccgcgcgg cgcgtgcgcc ggatcgcatc gctgacgctt gggcgagccg tctcgccgca
    13741 ggcacgagga ttgcgaaaag ttccgatgga tcaatcgctt ggcgcgcggc ggcgcgagat
    13801 atccacaagt ttgcgcacaa aaactgtgga aaactgccga gtcgaaaatg cgttgtggag
    13861 gattgtcgct gcgggctcgc tgccggccga ttcggcggcg gacggcgccc gtgaggcgcg
    13921 cggcgaaccg atttcagccg cgatgccgca tttctgacgg tttcgggaaa gcgccgccgg
    13981 atcaacgtgt tggacggcgg atgctcagga tgtccacaag cttgccaaca aaaattgtgg
    14041 aaaaggccat gcgggcgcga tgttcgatgt atcgacgccg gatgccaggg accggatgcc
    14101 ggatacggga taccggatgc gccgatgtcg atgtcgcgcg gcatgcggga gataaagcgt
    14161 gacaccggaa tatcggccga cagcgcgatt cgcatgtgtt gccgcttgtt tgacgcgttc
    14221 gggaaagggc cggcggatca aggggttgaa tgcccaatgc tcagcctgtc cacaagcttg
    14281 ccaacaaaaa ttgtggaaaa ggcggcggct ccggcgcggt gtaaacaggc cgagaagcgg
    14341 cggtgcgcgc tcgcggccat ggcggggagg accgcgagaa tcgagcgcca cggcgcgcgg
    14401 ccgtcggcgt ttgtagggcg gtttcgcggc ctgcgttgcc gcgtgccgct tgattgatcc
    14461 ggcgatgttt gtaccgccgg atcaatggct tgcggatcga atgcgcaaga tgtccacaag
    14521 cttggccaca aaaagtgtgg acaagccagt ctcgacgccg gctgcccacg gccgcgcccg
    14581 cgccgctatg ggcgcgggcg cggaggcgct cgacgattcg tgcgcggcgg ccgcgttgcc
    14641 tctttgcgag cgtggcggga aaaatgtcgc cggatcaatg ggttgtgcgg cggatgtgtg
    14701 ggatgtccac aagcttgacc acaaaaaatg tggacaagcg ctgcggcgat ccggtgggcg
    14761 gaggcgcgga gtccggcgag cggcgtccga ccgaacgcgc gccgtgccgg gacgcggggc
    14821 atcgatcggc atcgactgcc gtttatccga cctattcgac aaaagcgtga cggatcaacg
    14881 gattgagcgc tgcgcaccca ggatgtccac aagcttgcca acaaaaattg gggaaaacga
    14941 tcgtggtctc cgagcgcggt cggcgtggtg cgacgcgcgc ggcccgatcc gtcgacgtga
    15001 atcgatcggc gcgttcggcg ccgtgcggcg cgtgcgatac gcatgcgggc ggcgattgac
    15061 gcattcgtga catcgtcgcg aaaacgcttg cacatcaagg ggttgatcgc ttgatgcgca
    15121 ggatgtccac aagcttgcca acaaaaaatg tggaaaaggg cgaggcgtgt cgcgcaacga
    15181 acggggcaat tcgttcggtc caatcggtcc ggccgacgtt ggaccaacga cgacgaacaa
    15241 cgatgaacaa gaaccgacaa ccgacgagtg acgagtgacg cgcggcggcg cagtgcgcac
    15301 ggccaaacac ggatgacgcg atcgacagga tcaacgggcc catcgcgacc cacgacccac
    15361 gacccacgta cgaccttacg acccgcaaca acccacgcaa cgcgtcagcg accgacgccc
    15421 atccagccga cacccagcgc ccgcgagaag ggcctcgcca ccgctcacgc ctgtcgcgcg
    15481 gcaccgaagc gcaccgtgac cgtcagcccg cgcccatcgg cgccggcctc gagcgacacg
    15541 tccgcatgat gctgctcggc gatgcgcttg acgatcgaca acccgagccc gctgcccgac
    15601 gccgacacga gctgcgcgcc gccgccgcga tagaaccgct cccacacgcg ctcgcggtcg
    15661 gcggccggaa tgcccgggcc gttgtcgcgc acttcgagca ccggcgtgcc gccggcgtcg
    15721 atgcgcgcgt cgacgtcgac gcgcgcgccg gctcccgcat agcggatcgc gttgtcgacg
    15781 agattgttca gcagcacgcg cagcgtgtcc gcgttgccgg ccacccggac gggcgccgtg
    15841 ccgagcgcgc cgagatcgac gtgctgcgcg gccgcgatgc gcgcgcgctc ggcgaccacc
    15901 gagcggccga gcgcggcgag gtcgagctcg gcgaacggcg ccgatcgcgc ttcgggctcg
    15961 aggcgcgcga gcgtcagcaa ttgctcggcg agatgcgaca ggcgcgtcgt gccggcctga
    16021 atctgcgcga ggatgcgcgc acgctcgtcg gcgctcgccg tacgttgcag cagttgcgtc
    16081 tggatcgaca ggcccatgat cggcgtgcgc agctcgtgcg ccgcgtccgc gatgaaatgg
    16141 cgctgcagcg tgaacgagcg atcgagccgc gcgagcagat cgttgatctc ggaggcgagc
    16201 ggttgcgcct cggtcggcac ggtcgtgatg tcgagcggat cgaggcgatt cgcatggcgg
    16261 cgcttcaggc ccgcggcgat cgcgccgagc gggcgcagcc cgtagccgat gccgagccac
    16321 agcccgatcg cgagcagcgg cagcagcgac agcaccggcc acagcaggtg cacggcgatg
    16381 cccgcgatcg cctcccagcg cgcctggcgc ggctgcgcga cgcggatcgt cgtgcccgcg
    16441 ctctcgcgca catacgtgtg ccagcgctgg ccgccggcgt cgagcgtcac gaagccggcc
    16501 gcggcgggcg gcggcagttg cgtggccggg tcggtcgtga actcgagctt gccgccgcgc
    16561 cacacctgca gcagcacgtc gtcggaatcg tagtcggccg gatggcgctt ggcgagcctg
    16621 tcacgtccct cgatcgacag cttgccggcg tcgtcgacct gaatctgctt cgacatgctg
    16681 cgcatctggt cgtcgagcag atcgtcgagc tcgcgcagcg cgccccaata ggtgcccgtg
    16741 ctcgcgagca cgccgacgac gcacgcggcg ggcagcagcc acatcagcag ccgcccgcgc
    16801 agcgacgcgt tcaggcgccg cgcgaatccg cgcgcgcccg tcatgcgccg tctccgatcc
    16861 ggtagccgac gccgcgcacc gtgaggatcg tgtcgtggcc gagcttcttg cgcaggttgt
    16921 ggatatgcac ctgcaccgcg ttgctctcga tttcctcgcc ccagctgtac agccgctcct
    16981 cgaactgctc gcgcgagatc accgcgcccg gctcgcgcat cagctcgtgc agcagcacga
    17041 attccttcgg cgacagcgcg acttcctcgt cgccgcgcca cacctgatgg cgcgccggat
    17101 cgagccgcag cgcgccgacc gcgagcaccg tctgcgcgcg gccggcctgg cggcggttca
    17161 ccgcgcggat gcgcgcgagc agttcctcga gcgcgaacgg cttgacgagg taatcgtccg
    17221 cgccgcaatc gaggcccgcg atccggtcgg gcagcgcgtc gcgcgcggtg acgacgatca
    17281 cgggcagcgc gtcgtcgcgg cggcgcagcg cggcgagcac cgcgaggccg tccttgtccg
    17341 gcaggccgag gtcgagcagc agcaggccgt acgacgtcgt gcgcagcgcg agcgtcgccg
    17401 cgtcggcgtt ctgcgcccag tccaccgcga agccttcctg tttcagcccc tgttcgagcc
    17461 cgctgccgat gagcggatcg tcttcgacaa gcaatacgcg catgttcggt gattccgtct
    17521 gaatgcggcg cgcgcatgcg ggccgctggc ggcaatgata agcggtggat gcttagcggc
    17581 ggcttaaagc ggcgcggcgt cggcgccgtc gccggcgagg gggcgggtga taccatgtcc
    17641 gatcgacttt ccgagcgatc acgatgcccg ccgatttcga cgaactcgcg tccctgattc
    17701 gggcgcaatt ttccgagctg agcccgcaat tccaggtggg cgcggcgttc ctgctcgatc
    17761 atcccgacga ggtggccgtg tcgtcgatgc gcaaggtcgc gcagcgcgcg aatgtgcagc
    17821 cggcctcgct cgtgcggctc gcgcagcagt tcggctttcc gggctggaac gaactgcgcg
    17881 acctgttcgt cgcgcgcgtg cgcacgcggc cgcagccgct cacgcagcgc gcgcgctcgc
    17941 tcgtgaagcc gaatgcgaag gcgtcgctcg cggccgatct gctcgccgcg cagcggcaca
    18001 acctcgaggc gagcgccgcg cagaacgcgc gggcgctcac cgaggcggcg aagctgatcc
    18061 gcaaggccgc gcacgtgcat gtcgcgggct tccgctcgtg ctacccggtc gcgttcgggt
    18121 tcgtctacgg ctatcggctg ttccggccga cggtgtcgct gctcacgggc gtcgcgggct
    18181 cgctcgacat ggagctgcgc acgatcgcga agaacagcgt gaccgtggtc gtcagcttcg
    18241 cgccgtattc ggccgaagcg acgcgcgtcg cgcaggcggc gcgcgcgcag ggcggcagga
    18301 tcgtcgcgat caccgacagc gcggtgtcgc cgatcgcgct gcacgcggat gcgcaactga
    18361 tcttcacgca cgacagcccg tcgttcttcc cgtcgctcgt cgccgcgcat gcgctcgtgg
    18421 agacgctcgt cgcacaactg ctcgcgctcg agggcggcga ggcgatcgcg gcgctcgagc
    18481 aggccgaggc cgaattgcac gcgaagggcg cctacgtcgt ctgacatgcc gccgcgtacg
    18541 cgcggcatgc gaaaagcctt tcgcctcgcc ctatccggcg cgcatggatt tcctgcggcg
    18601 aatttgaata ttaaatcgct ccacaattgg aaacgtttcc acgcatcagt gcgccgaatt
    18661 agcgccggcc ccatttgctg cggcgcaaat ggattacgcc gggaagccgc ttcggaggcc
    18721 gttccgcacg ctcttcgggc ggccaaaggg ccgtaacgat gcggcgactt attaactcga
    18781 gtcggaaaaa aattttaatg gcgacttgcc ggttattcag acgattgcta atctgcggga
    18841 gatgaacaaa tagccggatc gaagatccgg aaaaatgaat aaataaatta tttccgagaa
    18901 aaggccacca tgacgactta ccgtgatacg cataccactt cgttccggat cggcgatgtc
    18961 gtgacgctca agacaggcgg tccgcgaatg acggtgacgt atgccggccc tgtcgtgttc
    19021 gacacgggcg aatgggtgat ctgccaatgg ttcgacgaga acggcgagtt ccgtcaagag
    19081 atgtttccga acgagaccgt cgtgctcgag ccgcggacga tttcggcggg actcgcgcgg
    19141 atgcgctcgc tgtcggtgcg cggcggcatg caggcgtgac gcctcgcatg cgccgggcgt
    19201 aaagaatttg tcaggaagac ggcgggcgtg tgaccgccga acgatgcgcc gcggcgccga
    19261 aagggcgcgc ggcgttgccg ttgttgcacg ccgcgcatga cgctgcgcgc gccgttcgcg
    19321 gcgatcatgc cgcatgcgcc gcgccgcgtc acgatgcacg gcccgccgaa cgagaaatgc
    19381 gtggcgggca ggggctcagc gggtgccttg cttgtcggcc cattgctcct gcgcggcgat
    19441 tcgccgctgc acacgctcga cgaggcccgt cgagaacgtc ttcatgctga gcgcacggcg
    19501 cttgagccgc acgtcgctca cgaaatcgtc ggtcgcgttc ggctgcagcg accagtacag
    19561 cgtcagcagc cagccgattc ccgtccagcc gaacagcgcg ttgaacagcg cgatcgtcag
    19621 tttgtcatcg cgatggcggc gatcggcgac gatcgccggg agaaagtaga gcgcgatcgc
    19681 gacgaccgag ccgacaatct ggatcaggat ttccatctgc atggtgcttc tccgtccgtg
    19741 ctgcggtgcg acttgacgtc gcacatgcaa tggaggtgat tgtcgcgctt ttttgcctgc
    19801 cgtgccgaca actaattgtt gcggtttcgt aacggatcgt tccccgccgt tcgctgcctt
    19861 acgccgcctt gccggcgtga cgcgccgttg ccgcgcgcga gcgcgaatcc ttcgtcgagc
    19921 cagcccgtca cgccgcccag catcagcttt accggccggc caaggcgcgc gagcctgagc
    19981 gccgcgcgcg cggcgccgtt gcagtgcggg ccggcgcaat agacgacgaa gcacgtgtcg
    20041 cgcgcaaatt cggacaactt gctttcaatg atctttcggt gcggcagatt gagcgcgccc
    20101 ggcacgtgcg cggccgcgta ctgctcgggg ccacgcacgt cgagcagcac gaaatcgggc
    20161 gcgccgcacg cgagtgcgtc gtgcacgtcc cggcaatcgg tttcgaacgc gagcgacgcg
    20221 gcgaagtggg cgacggcggc ggcgctgtcg gcggcgggaa tctcggtgac gtgggacatg
    20281 tccgttctcc tcgggacggt gatggtggca aacgagcgct cagtatccgc ggcgcccgcg
    20341 ccgtgcgata gtggcgcgat cgacaacttc cggtaacatc gcgccatgca ccctcatctc
    20401 gtcgtcgcgc tcgcctacga tcgcctctgc actttcgaat tcggctgcgt cgtcgaactg
    20461 ttcgcgctgc cgcggccgga gctcggcgtc gactggtatc gcttcgcggt ttgcgcgagc
    20521 gagccggggc cggtgcgcgc ggcgggcggc atcaaggtgc aggcgccgta tcggctcgcg
    20581 ctgatggatc gcgcggacac gatcgtgatt cccggctggc gcgatccgga cgaaacgccg
    20641 cccgagccgc tgctcaagaa gctccgcgcg gcgcaccggc gcggcgcgcg actatgctcg
    20701 atctgctcgg gcgtgttcgt gctggccgcg gcgggcgtgc tcgacggcgc gaccgtcacc
    20761 acgcactggc gctacgccga gcgcctgcag gcgcgctatc cggcgctgcg cgtgaatccc
    20821 gatgcgctct atgtcgacgc ggggcggatc gtcacgtcgg cgggttcggc ggcgggcctc
    20881 gacatgctga tgcatctcgt gcgccgcgat cacggcagcg cgatcgcgaa tcgcgtcgcg
    20941 caacggctcg tgctgccgcc gcatcgcgac ggcggccagg cgcagttcgt gccgcggccg
    21001 ctgccgagcg tcggcggcga ccggctcgcg aagctgatcg actggatgcg cgcgcacgcg
    21061 gggcagccgc atacgctcgc gtcgctcgcc gcgcgcgcgg cgatgagtcc gcgcacgctg
    21121 cagcggcagt ttcgcgacgc gaccgggctc ggcccgtacg aatggctgat ccgcgagcgg
    21181 gtcgggctcg cgaaggagat gatcgagcgc gatcccgcgt tgcccgtcgc gcgcgttgcc
    21241 gcgctcgcgg ggttcggctc tgaggagtcg ctgcgccggc atttcaggcg catcgcggcg
    21301 acgagtccgg ccgcgtatcg ccgcagtttc gatgcgggtt gactgcggcg ggcggggcga
    21361 tgcgcggcgc ggtggcgctt gcgtgcgggg agtggtgcgg aatcgatgag cggcgcgatc
    21421 cggcagcgtg cgcggcaggc tcgattcgag tcgatttgat tcgagccgaa tagagtcgaa
    21481 tagagtcgga tcgagtcggg gcagccgacc ggcgcgttcg acgtgcgcga tgcgtggcgc
    21541 ttggcgcgca aggcggcgag tgtcgtgatg gcgg
//
