LOCUS       NZ_CP009473            20609 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Burkholderia pseudomallei MSHR840 chromosome II, complete sequence.
ACCESSION   NZ_CP009473
VERSION     NZ_CP009473.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei MSHR840
  ORGANISM  Burkholderia pseudomallei MSHR840
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3108026)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.E.,
            Davenport,K.W., Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C.,
            Coyne,S.R., Broomall,S.M., Li,P.E., Teshima,H., Gibbons,H.S.,
            Palacios,G.F., Rosenzweig,C.N., Redden,C.L., Xu,Y., Minogue,T.D. and
            Chain,P.S.
  TITLE     Complete genome sequences for 59 burkholderia isolates, both
            pathogenic and near neighbor
  JOURNAL   Genome Announc 3 (2), e00159-15 (2015)
   PUBMED   25931592
  REMARK    Erratum:[Genome Announc. 2016 Apr 21;4(2):e00313-16. doi:
            10.1128/genomeA.00313-16. PMID: 27103731] Publication Status:
            Online-Only
REFERENCE   2  (bases 1 to 3108026)
  AUTHORS   Johnson,S.L., Bishop-Lilly,K.A., Ladner,J.T., Daligault,H.,
            Jaissle,J., Frey,K.G., Koroleva,G.I., Bruce,D.C., Coyne,S.R.,
            Broomall,S.M., Li,P.-E., Teshima,H., Gibbons,H.S., Palacios,G.F.,
            Rosenzweig,C.N., McMurry,K., Redden,C.L., Xu,Y., Currie,B., Mayo,M.,
            Minogue,T.D. and Chain,P.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-SEP-2014
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; Allpaths v.
            44837; Phrap v. SPS - 4.24; HGAP v. 2.2.0
            Genome Coverage                   :: 661x
            Sequencing Technology             :: Illumina; PacBio; 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000959185.1-RS_2024_06_16
            Annotation Date                   :: 06/16/2024 14:46:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,351
            CDSs (total)                      :: 6,275
            Genes (coding)                    :: 6,096
            CDSs (with protein)               :: 6,096
            Genes (RNA)                       :: 76
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 110 of 179
            Pseudo Genes (incomplete)         :: 100 of 179
            Pseudo Genes (internal stop)      :: 20 of 179
            Pseudo Genes (multiple problems)  :: 44 of 179
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:09:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 107993
            Orig. end                         :: 128602
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009473.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The DNA was obtained from USAMRIID.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20609
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="1"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20609
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20609
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10609](+)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10609
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     gene            complement(1208..1834)
                     /locus_tag="BG19_RS00500"
                     /old_locus_tag="BG19_3588"
     CDS             complement(1208..1834)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525297.1"
                     /locus_tag="BG19_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3588"
                     /product="LysE family translocator"
                     /protein_id="WP_004525297.1"
                     /transl_table=11
                     /translation="MFSAHLLLVYVAAVVAVYAVPGPDMAFVLQTGIGRGARHGAAAAA
                     GLGLARAVHVTLSACGVAALLKSAPWLYEAVRYGGALYLAYVAVQIFRSPAFALSAADA
                     AAPAARLRHTFVKGLLTNLLNPKALLFCSVLLPQFVQRGGAPVIAQMAVLGAVLVLAGL
                     CFDLACVAGATRIAGWLRAHPLAQLAQRWTFSAVLLGFALRLSID"
     misc_feature    1938..1949
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.57"
                     /tool="antismash"
     gene            1968..2432
                     /locus_tag="BG19_RS00505"
                     /old_locus_tag="BG19_3589"
     CDS             1968..2432
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188527.1"
                     /locus_tag="BG19_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3589"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_004188527.1"
                     /transl_table=11
                     /translation="MIELDKTDRAILAAVQLDGRIPVARLADSVGLSETPCARRLKRLE
                     SDGYIERYRAQLSRNALGFGVVAFVLLRCSVHDRSVANRFEREVLGIPRILSCHNVSGS
                     ADYLLQVVAHDLDDYGTFLRETLRVLPGVTSIESALSLREVKREAELPIP"
     gene            2709..3113
                     /locus_tag="BG19_RS00510"
                     /old_locus_tag="BG19_3590"
     CDS             2709..3113
                     /NRPS_PKS="Domain: Polyketide_cyc2 (10-130). E-value:
                     1.5e-14. Score: 46.5. Matches aSDomain:
                     nrpspksdomains_BG19_RS00510_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009934737.1"
                     /locus_tag="BG19_RS00510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3590"
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_045604418.1"
                     /transl_table=11
                     /translation="MTEAEPIRLEQFVARPPAQVWAALTTPAALARWWAAGDVRPVPGH
                     RFTLDMGPWGRQPCEVIAVEPERRFAIAFAQRTLDTTITWRLEPAPGGTRVCFEHAGFD
                     LDAPQARIAYDGMKRGWPSVLARIKQAIDG"
     aSDomain        2739..3098
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG19_RS00510_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.50E-14"
                     /label="BG19_RS00510_Polyketide_cyc2.1"
                     /locus_tag="BG19_RS00510"
                     /protein_end="130"
                     /protein_start="10"
                     /score="46.5"
                     /tool="antismash"
                     /translation="QFVARPPAQVWAALTTPAALARWWAAGDVRPVPGHRFTLDMGPWG
                     RQPCEVIAVEPERRFAIAFAQRTLDTTITWRLEPAPGGTRVCFEHAGFDLDAPQARIAY
                     DGMKRGWPSVLARIKQ"
     misc_feature    3476..3490
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.41"
                     /tool="antismash"
     gene            3504..5090
                     /locus_tag="BG19_RS00515"
                     /old_locus_tag="BG19_3591"
     CDS             3504..5090
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188605.1"
                     /locus_tag="BG19_RS00515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3591"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_004188605.1"
                     /transl_table=11
                     /translation="MNPLLSAAASEELGRTRHLGVALLVALLAAGVAYVFVHLFADLAP
                     VGPRSAFPYLLLGVALAIALGFEFVNGFHDTANAVATVIYTHSLTPNVAVIWSGLWNFL
                     GVMASTGAVAFGILQLLPVELILQVGHGAGFAMVFALLIAAIAWNLATWYFGLPSSSSH
                     TLIGSIIGVGLANQLMHGPSGTSGVDWAQAAGVGQSLLLSPLVGFLCAALLLAALKALV
                     RVPALYREPQTNEPPPFWVRCLLILTCTGVSFAHGSNDGQKGMGLIMLILIGTVPTAYA
                     LNKAVTPGETQTFIAVAHRASETLARYAGAAQPSPNPRADVEAYVQSRRLSDATLPAVR
                     RLSDALAAEVGATGSIAKVPEGQADNVRNTMYLVSEALRLMEKTGRPAFSPADRLALDD
                     YRRQLDHATKFIPTWVKVAVAIALGLGTMVGWRRIVVTVGEKIGKQHLTYGQGASAEVV
                     AMLTIGAADAYGLPVSTTHVLSSGVAGTMAANGSGLQWSTVRSLVLAWVLTLPASIVLA
                     GALYWAFHALT"
     gene            5240..6022
                     /locus_tag="BG19_RS00520"
                     /old_locus_tag="BG19_3592"
     CDS             5240..6022
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188398.1"
                     /locus_tag="BG19_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3592"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_038759788.1"
                     /transl_table=11
                     /translation="MNTLSEPRVPAARAHDETASGAAREAALARRIDALPWASIERDLE
                     RDGHAIVHGLLAPRTCEALAALYARDALFRSRVTMARHGFGRGEYQYFGYPLPRMVHAL
                     RTALYPHLAPIANRWHAQMRIDARFPAEHAHFIERCRAAGQLRPTPLLLRYREGDYNCL
                     HQDLYGEHVFPLQAAVLLSKPGADFAGGEFVITEQRPRMQSRADVVPLEQGDAVVFAVH
                     HRPVQGARGVYRVNLRHGVSRVRSGQRHTLGIIFHDAP"
     misc_feature    complement(5242..5253)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.02"
                     /tool="antismash"
     misc_feature    6357..6377
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.65"
                     /tool="antismash"
     gene            6618..8225
                     /locus_tag="BG19_RS00525"
                     /old_locus_tag="BG19_3593"
     CDS             6618..8225
                     /NRPS_PKS="Domain: AMP-binding (8-434). E-value: 7.3e-92.
                     Score: 300.0. Matches aSDomain:
                     nrpspksdomains_BG19_RS00525_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004551903.1"
                     /locus_tag="BG19_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3593"
                     /product="acyl-CoA ligase (AMP-forming), exosortase A
                     system-associated"
                     /protein_id="WP_045603483.1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-94, bitscore:
                     314.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNFFDLVEQAACRTPDAEALVAGDARLTYRALAALGLAFAERLQ
                     ALEIAQGERLAIFLDKRIETVVAMLGAAAAGVVFVPINPALKPEQVHHILVDSGARCLV
                     TSSLRARILGDGVLAGMPYVILTDAKTLAPAPASRTTFLRWMQPDAPPESVANRHASAA
                     PEPRADTIDADLAALLYTSGSTGRPKGVMLSHRNLLEGAWSVAQYLRHTAQDRILAALP
                     LSFDAGLSQLTTAWAAGASAVLVNYLMPADVVEVCVRERITGFAGVPPLWIQLARAAWP
                     GEARARLRYFANTGGHLPRPVLHALRELFPSASPYLMYGLTEAFRSTYLDPAEVDRRPD
                     SIGKAVPNARILVVREDGAPCAPNEVGELVHVGACVTLGYWNDPARTALRYRPSPEAKP
                     GGAPRETAVWSGDLVRRDDDGFLYFVARNDAQIKSSGYRISPEEIEEVAHASGLVAEAV
                     ALGVPHDELGESITLVVVPLDAGTFRPDALRARCAQQLPPYMVPHTIATRTSLPRNPNG
                     KFDRVALRADAANLVETL"
     aSDomain        6642..7919
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG19_RS00525_AMP-binding.1"
                     /evalue="7.30E-92"
                     /label="BG19_RS00525_AMP-binding.1"
                     /locus_tag="BG19_RS00525"
                     /protein_end="434"
                     /protein_start="8"
                     /score="300.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EQAACRTPDAEALVAGDARLTYRALAALGLAFAERLQALEIAQGE
                     RLAIFLDKRIETVVAMLGAAAAGVVFVPINPALKPEQVHHILVDSGARCLVTSSLRARI
                     LGDGVLAGMPYVILTDAKTLAPAPASRTTFLRWMQPDAPPESVANRHASAAPEPRADTI
                     DADLAALLYTSGSTGRPKGVMLSHRNLLEGAWSVAQYLRHTAQDRILAALPLSFDAGLS
                     QLTTAWAAGASAVLVNYLMPADVVEVCVRERITGFAGVPPLWIQLARAAWPGEARARLR
                     YFANTGGHLPRPVLHALRELFPSASPYLMYGLTEAFRSTYLDPAEVDRRPDSIGKAVPN
                     ARILVVREDGAPCAPNEVGELVHVGACVTLGYWNDPARTALRYRPSPEAKPGGAPRETA
                     VWSGDLVRRDDDGFLYFVARNDAQIKS"
     CDS_motif       7143..7202
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG19_RS00525_0001"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BG19_RS00525"
                     /protein_end="195"
                     /protein_start="175"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AALLYTSGSTGRPKGVMLSH"
     CDS_motif       7704..7787
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG19_RS00525_0002"
                     /evalue="7.90E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="BG19_RS00525"
                     /protein_end="390"
                     /protein_start="362"
                     /score="27.8"
                     /tool="antismash"
                     /translation="PNEVGELVHVGACVTLGYWNDPARTALR"
     CDS_motif       7887..7952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG19_RS00525_0003"
                     /evalue="8.30E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="BG19_RS00525"
                     /protein_end="445"
                     /protein_start="423"
                     /score="21.5"
                     /tool="antismash"
                     /translation="FVARNDAQIKSSGYRISPEEIE"
     gene            complement(8550..8819)
                     /locus_tag="BG19_RS30700"
     CDS             complement(8550..8819)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525293.1"
                     /locus_tag="BG19_RS30700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004525293.1"
                     /transl_table=11
                     /translation="MTLKLSANNIKCNNDCKSGVRIIEIHLAMAFDIFIPALRVFFAVC
                     NDPIGKAAGRGQIDTAIGILNRCCDAIGKFISFSSEPIFCADRE"
     misc_feature    complement(8625..8627)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8786..8802)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.71"
                     /tool="antismash"
     misc_feature    8792..8801
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.85"
                     /tool="antismash"
     misc_feature    8795..8809
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.94"
                     /tool="antismash"
     misc_feature    complement(8901..8915)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    8926..8941
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.3"
                     /tool="antismash"
     gene            8993..9685
                     /gene="bpsR3"
                     /locus_tag="BG19_RS00530"
                     /old_locus_tag="BG19_3594"
     CDS             8993..9685
                     /codon_start=1
                     /gene="bpsR3"
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188690.1"
                     /locus_tag="BG19_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3594"
                     /product="N-acyl-homoserine lactone dependent regulator
                     BpsR3"
                     /protein_id="WP_004188690.1"
                     /transl_table=11
                     /translation="MLSAALPESRDVRTLVETFRQAALQIGYQHHAIVELSGASHPASI
                     DVVSLHYPSEWVEHYTRNDYFAIDPVHRAAFRYSTPFSWNDVATANLRERHLLMEAEDA
                     GLDNGISIPLHQPLGRVLLVSLSGTAPTHDADAKWRNAYLLGMQFNLQFQSMRTCRPIP
                     PSVHLTDREQMCLTWVARGKSSWVIANMLDISKYTVDFHIENAMEKLNTRSRTFAAVKA
                     TRQGLIFP"
     misc_feature    complement(9956..9965)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            10001..10609
                     /gene="bspI3"
                     /locus_tag="BG19_RS00535"
                     /old_locus_tag="BG19_3595"
     CDS             10001..10609
                     /codon_start=1
                     /gene="bspI3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004528852.1"
                     /locus_tag="BG19_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3595"
                     /product="N-acylhomoserine lactone synthase BspI3"
                     /protein_id="WP_004528852.1"
                     /sec_met_domain="Autoind_synth (E-value: 9.9e-24, bitscore:
                     81.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYIIAGRLNELPPHVQTDLGAYRYDVFVRRLGWTIAGHSLDEHA
                     EWDEFDGPSTIHVVALDDAREICGYARLLPTTGPYLLRDVFAHLLGSSPAPQSPAVWEM
                     SRFAASRRRRSATEREPLGMAFFPSVLTVAASLGATRVVGVMTPSIERLYRRSGIALHR
                     LGNAMPGAGGSLSACSIDLPRLAFAPLGRKQCAACLAMH"
     misc_feature    10896..10912
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            10950..12275
                     /locus_tag="BG19_RS00540"
                     /old_locus_tag="BG19_3596"
     CDS             10950..12275
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004555031.1"
                     /locus_tag="BG19_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3596"
                     /product="NADH:flavin oxidoreductase/NADH oxidase family
                     protein"
                     /protein_id="WP_045603485.1"
                     /transl_table=11
                     /translation="MPDSNPTAAALLAQPLTLPNGTVLKNRLAKSALSEALCGHDGRVT
                     PQLIALYRRWSGSGAGLLVTGNVMIDGKALGEPGNVVIEDDRDLPRLREWAAAAKAHGS
                     EIWMQINHPGKQAMRGLNEETVAPSAIGFGPKLSPYFAVPRALTVDEIDALIRRYGTTA
                     AVAQQAGFTGVQLHGAHGYLINQFLSPQHNQRTDEWGGSAENRRRFVLAVYAEVRRRVG
                     PDFPIGIKLNSADFQRGGFTEEESLDVIRALAEAGIDLIEISGGTYETPVMQLGDRKAS
                     TIAREAYFLAFAEKVRADVKVPLMVTGGFRSLAGMEAPLRDGALDLIGLGRILSIEPDA
                     PARLLRGEETRHRVKPLSTGVKYFDSLGSLEVTWYTRQLHRIGKGRNPIPDENALKSFL
                     LDLSSKGCAIFKARRLRASSSEASAARGSATSVAGGPRHDAH"
     gene            complement(12603..13454)
                     /locus_tag="BG19_RS00545"
                     /old_locus_tag="BG19_3597"
     CDS             complement(12603..13454)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011853486.1"
                     /locus_tag="BG19_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3597"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_004528857.1"
                     /transl_table=11
                     /translation="MAATEPNADLALPLPATHAAASAAARRAPRVHAGHAAALATWVAL
                     AAGWWLAARFEWVSAALLPGPEAVLRKLVVLSTEGFDDATLGEHLLASVSRIATAFALA
                     IVTAIPVGILVATNRIVRGVVDPIVEFYRPIPPLAYLPLMVVWFGIGDASKILLIYLTM
                     FAPLAIATAAGASGVSESRLRAAASLGATRVQLLRHVVLPSALPDILTGVRIALGAGWS
                     TLVAAELIAATRGLGFMVYSASRFLVTDVVIAGILVIGAIALALEIGLRALQRRLTPWR
                     AD"
     gene            complement(13457..14239)
                     /locus_tag="BG19_RS00550"
                     /old_locus_tag="BG19_3598"
     CDS             complement(13457..14239)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006028946.1"
                     /locus_tag="BG19_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3598"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_004188097.1"
                     /transl_table=11
                     /translation="MAKLCAQQVSVVYASRRGALTALENVSMSVGSGEIVVALGASGCG
                     KSTLLSLLAGFQPPTSGRVSVDGAPVAGPGADRGVVFQDDALMPWLNVIENVAFGLRMQ
                     GVGRDARHARARDVLRLVKLAGFEQHRIDEISGGMRQRVGLARALAADPSFLLMDEPLG
                     ALDALTREHMQTLLLDVWRATGKGVFLITHSVEEAVLLATELLILSPRPGRIVARHSLD
                     FARRYAHGEPMRSIKSDPRFTEIHLALVEQLMRETEEV"
     gene            complement(14260..15270)
                     /gene="tauA"
                     /locus_tag="BG19_RS00555"
                     /old_locus_tag="BG19_3599"
     CDS             complement(14260..15270)
                     /GO_component="GO:0009897 - external side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015411 - ABC-type taurine transporter
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0030977 - taurine binding [Evidence IEA]"
                     /GO_process="GO:0015734 - taurine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tauA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525289.1"
                     /locus_tag="BG19_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3599"
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_004525289.1"
                     /transl_table=11
                     /translation="MILKRILIAASFTAAAASAVHSHAARAETVNVAYQYGADPAKLAQ
                     AGAAYEKATGWKINWRRFDSGADVVAALASGDVQLGDVGQSPFTAAVSRGVPIQAVALN
                     AITGVSEALVVRRGAHIDKPADLVGKTIATPYASNCHYALLAALKHWGIDAQRVKIVNL
                     GPTEIVAAWARGVIDAAYTWDPALGRAKASGGKVLVDSAEVGKWGAPTFDLWAVRSDFA
                     QAHPDFVSKFVKVTTQAIADYRANGKAWTSASRQVAEISRLSGAAAGDIAQLLAGNLYP
                     SAAEQASPELLGGGTADAIASTARFLKEQRKIDRVLPDYRPTVTDRFVRAAIAAR"
     misc_feature    15259..15274
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.08"
                     /tool="antismash"
     misc_feature    15458..15470
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.62"
                     /tool="antismash"
     gene            15543..16376
                     /gene="tauD"
                     /locus_tag="BG19_RS00560"
                     /old_locus_tag="BG19_3600"
     CDS             15543..16376
                     /EC_number="1.14.11.17"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (6-270). E-value: 6.7e-69. Score:
                     224.5. Matches aSDomain:
                     nrpspksdomains_BG19_RS00560_TauD.1"
                     /codon_start=1
                     /gene="tauD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004530602.1"
                     /locus_tag="BG19_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3600"
                     /product="taurine dioxygenase"
                     /protein_id="WP_004530602.1"
                     /sec_met_domain="TauD (E-value: 2.9e-67, bitscore: 224.5,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRLTLTRLTPALGAIVDDVDLSNATDALRDDIRAALAHHQVLFF
                     RGQRLSAARHRDFAAGFGDLHVHPIYPSHPDAREIMVLDNAVFDLQDNAIWHTDVTFTE
                     TPPRASILAAHTLPETGGDTLWGSGFAAYDALSGRVKAQLDGLTAQHDFTKSFPLKRFG
                     VTAEDRARWEKTRATHPSVAHPVVRTHPETGRKTLFVNEGFTTEIDGLPEEEGAALLRF
                     LFAHQSRPEFTLRWRWQPGDVAFWDNRSTIHYAVNDYGKAHRVMHRATIVGDRPY"
     aSDomain        15561..16352
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG19_RS00560_TauD.1"
                     /evalue="6.70E-69"
                     /label="BG19_RS00560_TauD.1"
                     /locus_tag="BG19_RS00560"
                     /protein_end="270"
                     /protein_start="6"
                     /score="224.5"
                     /tool="antismash"
                     /translation="TRLTPALGAIVDDVDLSNATDALRDDIRAALAHHQVLFFRGQRLS
                     AARHRDFAAGFGDLHVHPIYPSHPDAREIMVLDNAVFDLQDNAIWHTDVTFTETPPRAS
                     ILAAHTLPETGGDTLWGSGFAAYDALSGRVKAQLDGLTAQHDFTKSFPLKRFGVTAEDR
                     ARWEKTRATHPSVAHPVVRTHPETGRKTLFVNEGFTTEIDGLPEEEGAALLRFLFAHQS
                     RPEFTLRWRWQPGDVAFWDNRSTIHYAVNDYGKAHRVMHRAT"
     gene            complement(16642..16836)
                     /locus_tag="BG19_RS00565"
                     /old_locus_tag="BG19_3601"
     CDS             complement(16642..16836)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009977638.1"
                     /locus_tag="BG19_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3601"
                     /product="hypothetical protein"
                     /protein_id="WP_045603487.1"
                     /transl_table=11
                     /translation="MTNGNRNTPAARGDAPPPAHDIAGLARHVREIDPARYLDEQARLA
                     YRTALKRWPLVAKLMGLAD"
     gene            complement(16833..18389)
                     /gene="bcsG"
                     /locus_tag="BG19_RS00570"
                     /old_locus_tag="BG19_3602"
     CDS             complement(16833..18389)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030244 - cellulose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="bcsG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004549777.1"
                     /locus_tag="BG19_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BG19_3602"
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="WP_045603489.1"
                     /transl_table=11
                     /translation="MTFWNLYFILKLYLFAASHLKPLWIANLGFALALALSAPARRRGV
                     RLLRHALALALAVPLMYREADVPPLARLVETLGGLRAFSAGYWMELVPRFVPPMLALAA
                     LGVVIGYLIVNRWLRVATFVLLALIALPVWQAGSAALARLDAAAAAVPGPAGTGRAVQP
                     QDHNAALAAFRSQESQRQVTFSRPSADPATQFDVIVLHVCSLSWDDLDVARLRNHPLLG
                     HFDYLFTNFSTAASYSGPAAIRVLRASCGQEAHADLYKPAPAQCHLFGQLAAAGFAPQT
                     LLNHDGHFDNFLQLIRENIGVPNAPMIPNADAPVAMHAFDGSAIKDDYATLANWYAKRG
                     ASPGPVALYYNTISLHDGNQLTGGRMSSLDSYPLRARKLLDDFDRFADLIAASGRRAVI
                     VFVPEHGAALRGDAKQVAGLREIPTPRIVHGPVGVRLVGFKGDHGATTVIDAPASFFAL
                     AQLLANLVSNSPFKPGVTLSQYAADLPQTRMIGENEGTVTMTTPTGYAVKTPDGVWIDE
                     K"
     misc_feature    complement(18359..18373)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.19"
                     /tool="antismash"
     misc_feature    18958..18972
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    20319..20333
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.65"
                     /tool="antismash"
ORIGIN
        1 cgcgcccgcg atctcgatat cgagcgcgac ttcgccgtcc ggcccgctcg gatcgcccgt
       61 cggcgcgttg cgccccgcgc cgacgctcac gtcgacgagc ttcggctgcc gcgcgagccc
      121 gaggccgccg aaatactgct ggatctcggc cggccgatag ccgccgccga gctcgacgat
      181 cgcgatgcac tggcccgcgc cgtcgccggg cgggaaatcg tagagggccg cgagctgcgg
      241 cggcgtgtag gtgacggccg gcgcgcgcgc gggcaggaaa gtcggccgca gccggaaatg
      301 cggccgggcc tgcgggcggt cgtcgagccc gagtaccgcg gtgacgatgc catgcaactc
      361 gtcgggcagc gtgatatcgc ccgtgcggcc gcgatactgg ccgatcgacc gatgctcgaa
      421 gcgctcgagc ttcacgccga aggccgcctc gaactgcgcg atcgtgcccg acagcacgac
      481 gaggctctcg accggatcga cgcgcgcgac cgcgaggccg cgctgctgcg cgaatgcctc
      541 gactttcatg acgtcgtcgg gatgcgcgcc gaaacgctgg gcgaacgcct cgcgcgagac
      601 aggcttcacg cccggatcgc cgctcgcgag gccctgcaac aatgaatcga ggtgctgctc
      661 ttgctgtcgc cgcaacatca ccactacatg aatcgtctcg gccggatcgc acggcccgat
      721 gcacgtggat tcggcgacga gatgcgattc gttgccggcg tgaagatgcc ttgccatatt
      781 cggaccctcc agaagccgtg gtgacggatt gccaggattc ggacacggtc gcgcgatcgc
      841 agttccgggc ggtatgtcgg acggcgcaca cacgccgcca tggggagcgt gcgacagtac
      901 ggcaaagcaa gtgtaaagca cgcgcggcaa tcctgcgtgc gcatctcgcg cgcttgcgcc
      961 gcccgttcgc gacgttcggc gcgccgcgcg agatcgggca tgcgcacctg ccggcgcgcg
     1021 cgacgcgcat gcgacgcatg cagcgcgccg cgtcgacgcg atcgcgggcg atggcgcgcg
     1081 tttcgcgatt ggttgccgat tggttgcctc gcgtgccccg cgattcgccc cgcgcgccgc
     1141 gcttcgccgc cgcccgcgct cgtgcgcgcc gcatccgccg accggggcgg tccggggtcg
     1201 atcggaatca gtcgatcgac agccgcagcg cgaagccgag cagcacggcg gaaaacgtcc
     1261 agcgctgggc gagttgcgca agcggatgcg cgcgcaacca tccggcgatg cgcgtcgcgc
     1321 cggcgacgca cgcgagatcg aagcacaggc ccgcgagcac gagcaccgcg ccgagcaccg
     1381 ccatctgcgc gatcaccggc gcgccgcccc gctggacgaa ctgcggcagc agcaccgagc
     1441 agaacagcag cgccttcggg ttgagcagat tggtgaggag gcccttgacg aaggtatggc
     1501 gcagccgggc ggcgggcgcg gccgcgtcgg cggcggacag cgcgaacgcc ggcgagcgga
     1561 agatctgcac cgcgacgtac gcgaggtaca gcgcgccgcc gtagcgcacg gcctcgtaga
     1621 gccacggcgc gctcttcaag agcgcggcga cgccgcatgc ggacaacgtc acgtgcacgg
     1681 cgcgcgcgag cccgagcccc gcggcggcgg ccgcgccgtg ccgcgcgccg cgaccgatgc
     1741 ccgtctgcag cacgaacgcc atgtcggggc cgggcacggc atagacggcc acgacggcgg
     1801 cgacgtagac gagcagcaga tgagcggaaa acatgatcga acccgagtgg aaagggctcc
     1861 atgttgcacc cgctcgacga gcgctttttg gctaatttgg ccgaccgatg caccaaactg
     1921 attggaatac actaatagaa accgatttct tagagctttc ccacaacatg atcgaactcg
     1981 acaaaaccga ccgcgccatt ctcgccgcag tgcagctcga cggccgcatc ccggtcgccc
     2041 gcctcgccga ttcggtgggc ctgagcgaaa cgccgtgcgc gcgccggctc aaacgcctcg
     2101 aaagcgacgg ctacatcgaa cgctatcgcg cgcagctctc gcgcaacgcg cttggcttcg
     2161 gcgtcgtcgc gttcgtgctg ctgcgctgct cggttcacga tcgcagcgtc gcgaaccgct
     2221 tcgagcgcga ggtgctcggc attccacgca tcctgtcgtg ccacaacgtg tcggggtccg
     2281 ccgactatct gctgcaagtg gtcgcgcacg atctcgacga ctacggcacg ttcctgcgcg
     2341 agacgctgcg cgtgctgccc ggcgtcacgt cgatcgaatc ggcgctgtcg ctgcgcgagg
     2401 tgaaacgcga ggctgaactg ccgattccgt gaacgacgcc gcgaacggct ccgtcgccgc
     2461 atccgcggct gcccatggcg cgggtgggcc ggctgcggcc ggccctgtgt cctccgcgtc
     2521 ctccgcgtcc tccgcgtcct ccgcgccctc tgcgccttcg caccttcgca ccttcgtacc
     2581 tctgcacctc cgtgcccccg cgcatcccgc gctccgcggg caacgcgtcg cgccgacgag
     2641 ccgtatcgtc cgggggcggc atcccctatc atgcgcattc cgccacgcgc tttctcgaat
     2701 ccgacgcgat gaccgaagcc gaaccgatcc gcctcgagca attcgtcgcc cgcccgcctg
     2761 cgcaggtctg ggcggcgctc accacccccg cggcgctcgc gcgctggtgg gcggcgggcg
     2821 acgtgcgccc cgtccccggc caccgtttca cgctcgacat gggcccgtgg ggccggcagc
     2881 cgtgcgaagt gatcgcggtc gaacccgaac gccggttcgc gatcgcgttc gcgcaacgca
     2941 cgctcgacac gacgatcaca tggcggctcg agcccgcgcc cggcggcacg cgggtgtgct
     3001 tcgagcacgc gggcttcgat ctcgacgcgc cgcaggcacg cattgcctac gatggaatga
     3061 agcgcggctg gccttcggtg ctcgcgcgca tcaagcaggc gatcgacggc tgagcgcgcg
     3121 ccgcgcgcat gcgcggcgtg cgcccgccgc gccgccgccg aaccggagcg ccgaaccgga
     3181 gcgccgaatt cgggcgccga atcgcggtct cgaagcgcgc ccagaccgta gccgcggagc
     3241 gcggtttcgc atcgcaattc cgaaccgcgg ccatgcatcg cagcgatgaa tcgcggcgcc
     3301 gaaccgcgtg gccgagccgc gcgacagaat tgcgcggccc aatcttgcgc ggcccaatcg
     3361 cgtccccgaa tcccgcgccc gcgacgcgcc catgaccgac gcctccgagt cgcacacccg
     3421 aatcgccccc ctttgcgcgc tgtcatcaaa ctgcctgatc gcgagggcta ggatcgaacg
     3481 atccgttcca aacaagggcc gtcatgaatc cccttctgtc cgccgcggcg agcgaagagc
     3541 tcggtcgcac ccggcatctg ggcgtcgcgc tgctcgtcgc cctcctcgcc gccggcgtcg
     3601 cgtacgtgtt cgttcacctg ttcgcggatc tcgcgcccgt cggcccacgc tcggcgtttc
     3661 cgtatctgct gctcggcgtc gcgctcgcga tcgcgctcgg cttcgagttc gtcaacggct
     3721 tccacgacac cgcgaacgcc gtggcgaccg tgatctacac gcattcgctg acgccgaacg
     3781 tcgcggtcat ctggtcgggc ctctggaatt ttctcggcgt gatggcgtcg acgggcgcgg
     3841 tcgcgttcgg catcctgcaa ctgctgcccg tcgagctgat cctgcaagtc ggccacggcg
     3901 cgggcttcgc gatggtgttc gcgctgctga tcgcggcgat cgcgtggaat ctcgcgacct
     3961 ggtacttcgg cctgccttcg tcgagctcgc acacgctgat cggctcgatc atcggcgtcg
     4021 ggctcgcgaa tcagctgatg cacgggccgt ccggcacgag cggcgtcgat tgggcacagg
     4081 cggcgggcgt cggccaatcg ctgctgctct cgccgctcgt cggcttcctg tgcgcggccc
     4141 tgctgctcgc cgcgctgaag gcgctcgtgc gcgtgcccgc gctctaccgc gagccgcaga
     4201 cgaacgagcc gccgccgttc tgggtccgct gcctgctgat cctgacctgc accggcgtgt
     4261 cgttcgcgca cggctcgaac gacgggcaga aaggcatggg gctcatcatg ctgatcctga
     4321 tcggcaccgt gccgaccgca tacgcgctca acaaggcggt cacgcccggc gagacgcaaa
     4381 cgttcatcgc cgtcgcacac cgcgcgtccg aaacgctcgc ccgctacgcg ggcgccgcgc
     4441 agccgtcgcc gaacccgcgc gccgatgtcg aggcttacgt gcagtcgcgc cgcctgagcg
     4501 acgcgacgct gcccgcggtt cgccggttgt cggacgcgct cgcggccgaa gtcggcgcga
     4561 cgggctcgat cgcgaaagtg cccgaggggc aggcggacaa cgtgcgcaac acgatgtatc
     4621 tggtgtccga agccctgcgc ctgatggaga aaaccggccg gccggcgttc tcgccggcgg
     4681 atcgcctcgc gctcgacgac taccgcaggc agctcgacca cgcgaccaaa ttcattccga
     4741 cctgggtgaa ggtcgcggtg gcgatcgcgc tcggcctcgg cacgatggtc ggctggcggc
     4801 gcatcgtcgt gaccgtcggc gagaagatcg gcaagcagca tctgacctat gggcaaggcg
     4861 cgtcggcgga agtcgtcgcg atgctcacga tcggcgcggc cgatgcgtac gggctgccgg
     4921 tgtcgacgac gcacgtgctg tcttccggcg tcgcgggcac gatggccgcg aacggctccg
     4981 ggctgcaatg gagcacggtg cgcagcctcg tgctcgcgtg ggtgttgacg ctgcccgcgt
     5041 cgatcgtgct cgcgggcgcg ctctattggg ctttccacgc gctgacctga cgcgcatggc
     5101 ggcgtgacgg cccgcgcgcg agacatcgcg cgaaacataa tgcgcggccg aattgcagcg
     5161 caagatccgg tgtgcatcgc ttcgcccgcc ccgctagact ggccgcctcg atcccccacg
     5221 atgccgcgag gaagcgccga tgaatacgtt gtccgaacca cgcgtgccgg ccgcccgcgc
     5281 gcacgatgaa acggcgagcg gcgcggcgcg cgaagccgcg ctcgcgcggc ggatcgacgc
     5341 gttgccgtgg gcgtcgatcg aacgggatct cgagcgcgac ggccatgcga tcgtgcatgg
     5401 gctgctcgcg ccgcgcacgt gcgaagcgct cgccgcgctc tacgcgcgcg acgcgctgtt
     5461 ccgcagtcgc gtgacgatgg cacgccacgg gttcggccgc ggcgaatacc agtatttcgg
     5521 ctacccgctg ccgcgcatgg tccacgcgct gcgcaccgcg ctgtacccgc acctcgcgcc
     5581 gatcgcgaac cgctggcatg cgcagatgcg catcgacgcg cggtttcccg ccgagcacgc
     5641 gcacttcatc gagcgttgcc gcgcagccgg acaactgcgt ccgacaccgc tgctgctgcg
     5701 ctatcgcgaa ggcgactaca actgcctgca tcaggatctg tatggcgagc acgtattccc
     5761 gctgcaggcg gcggttctgc tgtcgaagcc gggcgccgat ttcgcgggcg gcgaattcgt
     5821 gatcaccgag caacggccgc gcatgcaatc gcgcgccgat gtcgtgccgc tcgagcaggg
     5881 cgacgcggtc gtgttcgccg tccatcatcg cccggtgcaa ggcgcgcgcg gtgtctatcg
     5941 cgtgaatctt cggcacggcg tgagccgcgt gcgctccggg cagcgccata cgctcgggat
     6001 catcttccac gacgcgccgt gacgccggcg ctcgcgctgg cgcgcgcgca ccgcgcgcgc
     6061 accggcagcc cgccatcgga cgccgcgccg gccgacgcat gcgcacgcgc acgcacgcgt
     6121 gcggcgcacg gccgccggaa cgaatcgcaa tggttgcgca cacatccatt cgccgcgaag
     6181 cgtgcatctc gcgccgccat ggaaagacgc ggcgcgacac cggttccttg cgggcgatgc
     6241 gagctcgcct cggcgcgtgc cgctcgacat gcgatgcgtt cgcccgcgcg acacatgcaa
     6301 ccgaattgaa agaccgtgtc cgagcgcgcc ggcgaaattc atcaggacaa ttgacgatca
     6361 cgtcgagcag acgatctcct ccatgcgcgc gcgtgtgcat gtcgaatgtg ctagcgcggc
     6421 gcgcggccgc atccgtcaat gttcggcacc accccgttcg gccatttaca tcgatgcgcc
     6481 gcgaccgcgc gccgtgtcca ttcgctactc tttcggcagc caggatcggc cgcgttcgcg
     6541 cgacggtcgt tagccatcgc gagcttcgcc gcatcgctcg acgtgcgccg cccgagtttc
     6601 aaaacggagg tggaatcatg cgtaatttct tcgatctggt cgaacaggcg gcatgccgca
     6661 cacccgatgc cgaggcgctc gtcgccggcg acgctcggct cacctatcgc gcactcgcgg
     6721 cgctcggcct ggcgttcgcc gagcggctgc aagcgctcga gatcgcccag ggcgagcggc
     6781 tcgcgatctt tctcgacaag cgcatcgaga cggtcgtcgc catgctcggc gccgcggcgg
     6841 ccggcgtcgt gttcgtgccg atcaacccgg ccctcaagcc cgaacaggtt catcacatcc
     6901 tcgtcgacag cggcgcgcgc tgtctcgtca cgtcgtcgct gcgcgcgcgc atactcggcg
     6961 acggcgtgct cgcaggcatg ccgtacgtga tcctgaccga tgcgaagacg cttgcaccgg
     7021 cgccggcttc gcgcaccacg tttctgcgat ggatgcagcc cgatgcgccg cccgagtccg
     7081 tcgcgaaccg gcacgcgagc gccgcgcccg agccgcgagc ggacacgatc gacgccgatc
     7141 tcgccgcgct cctttacacg tccggctcga cgggccgccc caagggcgtg atgctcagcc
     7201 accgcaatct gctcgagggc gcgtggagcg tcgcgcaata cctgcgccat accgcgcagg
     7261 atcgcattct cgccgcgctg ccgctcagct tcgacgccgg cctgagccag ttgacgaccg
     7321 catgggccgc gggcgcgagc gccgtgctcg tcaactacct gatgcccgcg gacgtcgtcg
     7381 aggtctgcgt gcgcgaacgc atcaccggct tcgcgggcgt accgccgctc tggattcagc
     7441 tcgcgcgcgc ggcgtggccc ggcgaagcgc gcgcgcggct gcgctatttc gcgaacaccg
     7501 gcggtcatct gccgcggccg gtgctgcacg cgctgcgcga actgtttccg agcgcgtcgc
     7561 cgtatctgat gtacgggctg accgaagcgt tccgctcgac ctacctcgat cccgccgaag
     7621 tcgaccgtcg ccccgattcg atcggcaagg cggtgccgaa cgccagaatt ctcgtcgtgc
     7681 gcgaggacgg cgcgccgtgc gcgccgaacg aggtcggcga gctggtccac gtcggcgcgt
     7741 gcgtgacgct cggctactgg aacgatccgg cgcgcaccgc gctgcgctac cggccttcgc
     7801 ccgaggcgaa gccgggcggc gcgccacgtg agacggccgt ctggtccggt gatctcgtgc
     7861 gccgcgacga cgacggattc ctctatttcg tcgcccgcaa cgatgcgcag atcaagagtt
     7921 ccggctaccg gatcagcccg gaagagatcg aggaggtcgc gcacgcgagc gggctcgtgg
     7981 ccgaagcggt cgcgctcggc gtgccgcacg acgagctcgg cgaatcgatc acgctcgtcg
     8041 tcgtgccgct cgacgccggc acgttcaggc ccgacgcgct gcgcgcgcga tgcgcacagc
     8101 aacttccccc gtacatggtg ccgcatacga tcgccacgcg cacgtcgctg ccgcgcaatc
     8161 cgaacgggaa attcgatcgc gtcgcgctgc gcgccgacgc ggcgaacctc gtcgaaacgc
     8221 tctgaagacg cgccggatcg ccgcgcgaga cgctcgtcta cgcgcgacgt ccgccgcccg
     8281 cctccgttgc ctacgccgta cccggcgccc cgggcggcgc gacgttgcga acgcgcgcgc
     8341 tggggcaccg cggcagcggg cgccgccgcg cgcgccgctt cgggccgagc cgcggcaggc
     8401 gccggctcgc gttccgccac gaatatattc gcgcgccgtt tctcgacgaa aaacaagaat
     8461 ttaccgcaca tctaataaga cggaatccgg cggaataatc attcgacacc atcctcggct
     8521 gacagcgatt tcgcatgaag attcggcact tactcgcgat ccgcgcaaaa gattggctca
     8581 ctcgaaaatg aaatgaactt acctattgca tcgcagcatc ggtttaaaat accgattgcc
     8641 gtatcgatct gtccacgccc tgccgccttg ccgatcggat cgttgcagac agcgaaaaat
     8701 acccgaagcg ccgggataaa aatatcgaac gccatcgcca aatgaatctc gattatccga
     8761 acgccgctct tgcaatcgtt attgcatttg atattatttg cagacaattt caacgtcatt
     8821 gcgttatccg attttcattg gcgacgcgtc cccaacccgg tacacggcac ttcgaaagtc
     8881 ttgattttca ataacggggg catgcaaatt gagcaggctg cttcaacgcg aatatcgaac
     8941 aggtggagat gacggtgcgg ggtcgtcgtc gggagaaagc gcttcgacac ccatgctctc
     9001 cgccgcgttg ccggaatcgc gcgacgtccg cacgctggtc gagactttcc ggcaggcggc
     9061 gctgcagatc ggctaccagc accatgcgat cgtcgagctg tcgggcgcat cgcatccggc
     9121 gtcgatcgac gtcgtctcgc tgcactatcc gtccgagtgg gtcgagcact acacccgcaa
     9181 cgactacttc gcgatcgatc ccgtccatcg cgcggcattc cgctacagca cgccgttctc
     9241 gtggaacgac gtcgcgacgg cgaacctgcg cgagcggcat ctgctgatgg aagccgagga
     9301 cgcgggcctc gacaacggca tcagcatccc gctgcatcag ccgctcggac gcgtgctgct
     9361 ggtgagcctg tccggcaccg cgccgacgca cgatgccgat gcgaaatggc gcaacgcgta
     9421 cctgctcggc atgcagttca atctgcagtt ccagagcatg cgcacgtgcc gcccgattcc
     9481 gccgtccgtc cacctgacgg atcgcgaaca gatgtgcctc acgtgggtcg cgcgcggcaa
     9541 gtcgtcgtgg gtcatcgcga acatgctcga catctccaaa tacacggtcg acttccacat
     9601 cgagaacgcg atggagaagc tcaacacgcg cagccgcacg ttcgccgccg tgaaggcgac
     9661 gcggcagggg ctcatctttc catgagcgcg cgatccatcc ggatccgtta gcgccgcccg
     9721 tttcatccgc caccgcgcgc cgacgcgatg caaccggccg cttgcatcgg actgccgatc
     9781 gatgccgcgc cggcctgcgc gccgaacgcc gccgaccgcc ctcgtcgcgc ctcgcggcga
     9841 ggccgcgccg cgcgcgcgca ttgccgtatc gccgcgcctt cgtgtcgcgc aacagccttc
     9901 gagaccgcgc acgcgtgctt ctcgaccctc accgctcata cgcgatcgga acgcgcgccg
     9961 ccttcgcgcc gacgatcgat ccatcggaga accaagcgcc atgtcataca tcatcgcggg
    10021 ccgattgaac gaactgccgc cgcacgtcca gaccgatctc ggcgcgtatc gctacgacgt
    10081 gttcgtgcgc cggctcggct ggacgatcgc cggccactcg ctcgacgaac atgcggagtg
    10141 ggacgagttc gacgggccgt cgacgattca tgtcgtcgcg ctcgacgacg cgcgcgagat
    10201 ctgcggctac gcacgcctgc tgccgacgac gggcccgtat ctgctgcgcg acgtgtttgc
    10261 gcatctgctc ggctcgtcgc ccgcgccgca atcgcctgcc gtctgggaaa tgtcgcgctt
    10321 cgccgcgtcg cggcggcggc gaagcgcgac cgagcgcgag ccgctcggca tggcgttctt
    10381 tccgtcggtg ctcacggtgg ccgcgtcgct cggcgcgacg cgcgtggtcg gcgtgatgac
    10441 gccatcgatc gaacgcctgt accgccgctc gggcatcgcg ctgcatcgcc tcggcaacgc
    10501 gatgccgggc gcgggcggca gcctgtccgc atgctcgatc gatctgccgc gcctcgcgtt
    10561 cgcgccgttg ggccgcaagc agtgcgcggc gtgcctggcg atgcattgac caggaaggcg
    10621 ggcgcatcgg gcgagacacg cgtcttgtcg tttttgccga tgtcgacgcg ctcgcctgac
    10681 gccatcgccc ggtgcgtcgc gacgccgcgc gccgccgaat tggacgttct cctctaaccg
    10741 gaccgccaac gcgccgccgg gcggcgggcc gccacggacg cggaccgccg cccgtcgccc
    10801 cgttcgcccg cccggcacgc ccatcgccgt gcgggtcgct ccgtcttgac tcagttccga
    10861 ttttgaactt acgatcccaa ccaatacatc aatcgatgta acattactcg atggattttc
    10921 ggtcgtcgac ccaaccggag cgtcatgcca tgcccgattc gaatcccacc gcggccgcgt
    10981 tgctcgcgca gccgctcacg ctgccgaacg gcaccgtgct gaagaaccgc ctcgcgaaat
    11041 cggcgctgag cgaagcgctg tgcgggcacg acggccgtgt gacgccgcag ctgatcgcgc
    11101 tgtaccggcg ctggtcgggt tcgggcgcgg ggctgctcgt caccggcaac gtgatgatcg
    11161 acggcaaggc gctcggcgag cccggcaacg tcgtgatcga ggacgaccgc gatctgccgc
    11221 gtctgcgcga atgggccgcg gccgcgaaag cgcacggcag cgagatctgg atgcagatca
    11281 atcatcccgg caagcaggcg atgcgcggac tcaacgagga aaccgtcgcg ccgtcggcga
    11341 tcggcttcgg gccgaagctt tcgccgtatt tcgcggtgcc gcgcgcgctg accgtggacg
    11401 agatcgacgc gctgatccgg cgctacggaa cgacggccgc cgtcgcgcag caggcgggct
    11461 tcaccggcgt gcagttgcac ggcgcgcacg gctatctgat caaccagttc ctgtcgccgc
    11521 agcacaatca gcgcaccgac gaatggggcg gcagcgcgga gaaccgccgg cgcttcgtgc
    11581 tcgcggtgta cgcggaagtg cggcgccggg tgggccccga ttttccgatc ggcatcaagc
    11641 tcaattcggc cgatttccag cgcggcggct tcaccgagga agaatcgctc gacgtgatcc
    11701 gcgcgctcgc cgaggcgggc atcgatctga tcgagatttc cggcggcacc tacgaaacgc
    11761 ccgtgatgca gctcggcgac cgcaaggcgt cgacgatcgc gcgcgaagcg tacttcctcg
    11821 cgttcgccga gaaggtgcgc gcggacgtga aggtgccgtt gatggtcacg ggcggctttc
    11881 gcagcctcgc cggcatggag gcaccgctgc gcgacggcgc gctcgacctg atcggcctcg
    11941 ggcgtatcct ctcgatcgag cccgacgcgc ccgcgcgcct gctgcgcggc gaggaaacgc
    12001 gccatcgcgt gaagccgctc agcacgggcg tcaaatactt cgatagcctc ggttcgctcg
    12061 aagtcacgtg gtatacgcgg cagctccatc gaatcggcaa ggggcgcaat ccgattcccg
    12121 acgagaatgc gctgaaatcg ttcctgctcg acctgtcgtc gaagggctgc gcgatcttca
    12181 aggcgcgtcg cctgcgtgct tcgtcctccg aagcgtcggc cgcgcggggt tcggcgacgt
    12241 cggtcgccgg cggcccgcgg cacgatgcgc attgagcggg gcgacccgcc tcgcgcaacg
    12301 gcgccgcgcg gcgcgcggca tcggcgcatc gaatgcgctt tgctcgatgc ttcgcgcgtt
    12361 gaagcggcga tggatagccg tgccgatgtc gatatcaact tcgccgctca tcgctcatcg
    12421 acgataaggg ataaggcgaa acgccgatga aacgaagcgg cgcgcgcgtg atagcagatg
    12481 aaccgccgca catcgtcacg gaccgccacg aaccggcgca acgccggtgc gatctcggcg
    12541 gctccggtcg atcggccgcc cccccgcgcc cctgaccccc accgcatcgc aaacgcgccg
    12601 cgctaatcgg cccgccacgg cgtcaatcgc cgctgcagcg cgcgcaagcc gatttccagc
    12661 gcgagcgcga tcgcgccgat cacgaggatc cccgcgatca cgacgtccgt cacgaggaac
    12721 cgtgacgcgg aatacaccat gaagccgagc ccgcgcgtcg ccgcgatcag ctccgccgcg
    12781 acgagcgtcg accatcccgc gccgagcgcg atgcgcacgc cggtcaggat gtccggcagc
    12841 gcgctcggca gcacgacgtg gcgcagcagt tgcacgcgcg tcgcgccgag cgacgcggcc
    12901 gcgcgcaggc ggctttccga tacgccgctc gcgcccgcgg cggtcgcgat cgcgagcggt
    12961 gcgaacatcg tcagatagat cagcaggatt ttcgacgcgt cgccgatccc gaaccagacg
    13021 accatcaacg gcagatacgc gagcggcgga atcggccggt aaaactcgac gatcggatcg
    13081 acgacaccgc gcacgatccg gttcgtcgcg accaggatgc cgaccgggat cgcggtgacg
    13141 atcgcgagtg cgaacgccgt cgcgatccgc gacacgctcg cgagcagatg ttcgccgagc
    13201 gtcgcgtcgt cgaaaccctc ggtgctcagc acgacgagct tgcgcagcac ggcctcgggg
    13261 cccggcagca gcgcggccga tacccattcg aagcgcgcgg cgagccacca gccggcggca
    13321 agcgcgaccc acgtcgcgag cgcggccgcg tggcccgcat gcacgcgcgg cgcgcggcgc
    13381 gccgccgcgc tcgcggccgc atgggttgcc ggcagcggca gcgcgagatc ggcattcggt
    13441 tcagtggcgg ccaacgtcaa acctcctcgg tttcgcgcat caactgctcg acgagcgcga
    13501 gatggatttc ggtgaagcgc ggatcgctct ttatcgagcg catcggttcg ccgtgcgcgt
    13561 agcgccgcgc gaagtcgagc gaatgccgcg cgacgatccg gccagggcgc ggcgacagga
    13621 tcagcagctc ggtcgcgagc aacaccgctt cctcgacact gtgcgtgatc agaaacacgc
    13681 ccttgcccgt cgcgcgccac acgtcgagca gcagcgtctg catgtgctcg cgcgtgagcg
    13741 cgtcgagcgc gccgagcggc tcgtccatca gcaggaacga cgggtccgcg gcgagcgcgc
    13801 gcgcgagccc gacgcgctgc cgcatgccgc ccgaaatctc gtcgatccga tgctgctcga
    13861 agccggcgag cttcacgagc cgcagcacgt cgcgcgcacg cgcgtggcgt gcgtcgcggc
    13921 cgacgccttg catccgcagc ccgaacgcga cgttctcgat cacgttcagc cacggcatca
    13981 gcgcgtcgtc ctgaaacacg acgccgcgat cggcgccggg ccccgcgacg ggcgcgccgt
    14041 cgacgctcac gcggcccgac gtcggcggct gaaagccggc gagcagcgac agcagcgtgc
    14101 tcttgccgca gccggacgcg ccgagcgcga caacgatctc gccgctgccg accgacatcg
    14161 atacgttctc gagcgccgtc agcgcgccgc gacgcgacgc gtagacgacg gatacctgtt
    14221 gcgcgcaaag cttcgccatg ccgatgccgc cgcgtcgtct cagcgcgcgg cgatcgccgc
    14281 gcggacgaac cggtccgtca ccgtcggccg gtaatcgggc agcacgcggt cgatcttgcg
    14341 ctgctccttc aggaagcgcg cggtcgacgc gatcgcgtcg gccgtgccgc cgccgagcag
    14401 ctcgggcgac gcctgctcgg ccgcgctcgg gtagagattg ccggcgagca gttgcgcaat
    14461 gtcgcccgcc gccgcgccgc tcagccgcga gatttcggcg acctgccgcg acgcgctcgt
    14521 ccatgctttg ccgttcgcgc gatagtcggc gatcgcctgc gtcgtcacct tcacgaactt
    14581 cgacacgaaa tccggatgcg cttgcgcgaa atcgctgcgc accgcccaca gatcgaatgt
    14641 cggcgcgccc cacttgccga cttcggccga atcgacgagc accttgccgc cgctcgcctt
    14701 cgcgcggccg agcgccgggt cccacgtata ggcggcgtcg atcacgccgc gcgcccatgc
    14761 ggcgacgatc tcggtcggcc cgagattcac gatcttcacg cgctgcgcat cgatgcccca
    14821 gtgcttgagc gcggcgagca gcgcgtaatg gcagttcgac gcgtaaggcg tcgcgatcgt
    14881 cttgccgacg agatcggccg gcttgtcgat atgcgcgccg cggcgcacga cgagcgcctc
    14941 ggacacgccg gtgatcgcgt tcagcgcgac cgcctggatc ggcacgccgc gcgacaccgc
    15001 cgcggtaaac ggactctgcc cgacatcgcc gagctggaca tcgcccgagg cgagcgccgc
    15061 gacgacatcc gcgcccgaat cgaagcggcg ccagttgatc ttccagccgg tggccttctc
    15121 gtacgcggcg cccgcctgcg cgagcttcgc cggatcggcg ccgtactgat aggcgacgtt
    15181 caccgtctcc gcccgggcgg cgtgcgaatg aacggccgag gccgcggcgg cggtgaaaga
    15241 cgcggcgatg aggatgcgct tgagaatcat gaacgggcct tcccttctgc tggatgcgtt
    15301 gaattcggat ggccgtcgag attaccggct tgcgcgccgt ccgttaaaca acgaaatctg
    15361 cgaaggatat gagacggcgc attcggcgat ggcgccaagc cggccgcaat ccccgcgcga
    15421 cgataagcaa tgcggatttc gttggttcac caaacgaacg cgttttgcga gacttggcgg
    15481 ctttccgcca tgcgaggcgc gcgccggcgc accgaggcgc accgacgata tccggaccga
    15541 cgatgacccg actgacattg acccgactca cgcccgcgct cggcgcgatc gtcgacgacg
    15601 tggacctctc gaacgcgacc gacgccctgc gcgacgacat ccgcgccgcg ctcgcgcacc
    15661 atcaggtgct gttcttccgc ggccagcgcc tgagcgcggc ccggcatcgc gacttcgcgg
    15721 ccggattcgg cgatctgcac gtgcacccga tctatccgtc gcatccggac gcgcgcgaga
    15781 tcatggtgct cgacaacgcc gtgttcgacc tgcaggacaa cgcgatctgg catacggacg
    15841 tgacattcac cgagacgccg ccgcgcgcgt cgatcctcgc cgcgcacacg ctgcccgaga
    15901 cgggcggcga cacgctgtgg ggcagcggct tcgccgcgta cgacgcgctg tccgggcgcg
    15961 tgaaggcgca gctcgacggc ctcaccgcgc agcacgattt cacgaagtcg tttccgctga
    16021 aacgcttcgg cgtcaccgcc gaggatcgcg cgcgctggga gaagacgcgt gcgacgcatc
    16081 cgagcgtcgc gcatcccgtc gtgcgcacgc acccggagac cggccgcaag acgctgttcg
    16141 tcaacgaagg cttcacgacc gagatcgacg ggctgcccga agaggaaggc gccgcgctgc
    16201 tgcgcttcct gttcgcgcat cagtcgcggc ccgagttcac gctgcgctgg cgctggcagc
    16261 cgggcgacgt cgcgttctgg gacaaccgct cgacgatcca ttacgcggtg aacgactacg
    16321 gcaaagcgca tcgggtgatg caccgcgcga cgatcgtcgg cgacaggccg tattgagcgg
    16381 gcggcgcggg gattccggag aggcttcgcc ggccgcgggt tcgttcgtcg gtcggctcgc
    16441 cgcttcgttc gccggctcgt tcgcgggcct gccgtatcgg ctcgttcatc ggcccgttca
    16501 tcggcccgct catcggcccg cccatcggcg ccgcatggcg ctccgttcgt cgtcccgctc
    16561 gttcaccggc ggctcgtcgg ccggccattc gcctgccgcg ggcgcgcgcc gtcgcgcgcg
    16621 tcgcggggcg cggctcgcgc gtcaatccgc gagccccatc agcttcgcga ccaacggcca
    16681 cctcttaagc gccgtgcggt acgcgagccg cgcctgctcg tcgagatagc gcgccggatc
    16741 gatctcgcgc acgtggcgcg cgagccccgc aatgtcgtgc gccggcggcg gcgcgtcgcc
    16801 gcgcgccgcc ggcgtgttcc gattcccgtt cgtcattttt cgtcgatcca tacgccgtcc
    16861 ggcgtcttca ccgcgtagcc cgtcggcgtc gtcatcgtca ccgtgccctc gttctcgccg
    16921 atcattcgcg tctgcggcag atcggccgcg tattgcgaca gcgtcacgcc cggcttgaac
    16981 gggctgttcg acacgagatt cgccagcagt tgcgcgagcg cgaagaagct cgccggcgcg
    17041 tcgatcacgg tggtcgcgcc gtggtcgccc ttgaagccga cgagccgcac gccgaccggc
    17101 ccgtgcacga tccgcggcgt cggaatctcg cgcagccccg ccacctgttt cgcgtcgccg
    17161 cgcagcgccg cgccgtgctc gggcacgaac acgatcaccg cgcgccgccc cgatgcggca
    17221 atgagatccg cgaagcggtc gaagtcgtcc agcagcttgc gcgcgcgcag cgggtacgaa
    17281 tcgaggctcg acatccggcc gcccgtcagc tgattgccgt cgtgcaggct gatcgtgttg
    17341 tagtacagcg cgacggggcc ggggctcgcg ccgcgtttcg cgtaccagtt cgcgagcgtc
    17401 gcgtagtcgt ccttgatcgc cgagccgtcg aacgcgtgca tcgcgacggg cgcgtccgcg
    17461 ttcgggatca tcggcgcgtt cggcacgccg atgttctcgc ggatcaactg gagaaagttg
    17521 tcgaagtggc cgtcgtggtt gagcagcgtc tgcggcgcga agccggcggc cgcgagttgc
    17581 ccgaacagat ggcactgcgc gggcgcgggc ttgtacaggt ccgcgtgcgc ctcctgcccg
    17641 cagctcgcgc gcagcacgcg gatcgcggcc gggccgctgt agctcgccgc cgtgctgaaa
    17701 ttcgtgaaca gatagtcgaa atggccaagc agcggatgat tgcgcagcct cgcgacgtcg
    17761 aggtcgtccc acgacagcga gcacacatgc agcacgatca cgtcgaactg cgtcgccgga
    17821 tcggcgctcg gccggctgaa cgtcacctgc cgctgcgatt cctgcgagcg gaacgcggcg
    17881 agcgccgcgt tgtgatcctg cggctgcacg gcgcggcccg ttccggccgg cccgggcacg
    17941 gccgcggcag ccgcgtcgag ccgcgcgagc gccgcgctgc ccgcctgcca caccggcagc
    18001 gcgatcagcg cgagcagcac gaacgtcgcc acgcgcagcc agcgattgac gatcagatag
    18061 ccgatcacga cgccgagcgc ggccaatgcg agcatcggcg gcacgaagcg cggcacgagc
    18121 tccatccagt agccggcgct gaacgcgcgc aggccgccga gcgtttcgac gagccgcgcg
    18181 agtggcggca cgtccgcttc gcgatacatc agcggcaccg cgagcgccag cgcaagcgcg
    18241 tggcgcagca gccgcacgcc gcgccgcctc gccggcgcgc tcagcgcgag cgccagcgcg
    18301 aaaccgagat tcgcgatcca caacggcttc aagtggctcg ccgcgaacag atagagcttc
    18361 agaatgaaat acagattcca gaacgtcatc gacgcgactc cgtcatcagt tgaatccgcg
    18421 cgtcaatgac gcgtccggtc ggccgcgcgc cgcgcccgca ccgcgctcgt cgcggcccgc
    18481 agcatccgtg cgtagccttc gaaccccatc gacagcacct ccttcagccc gcgcagcggc
    18541 gcatcgtcgt gctcggcgcg cgcgtcgcgc cagtcgagcc acgcatccgc gcggccgaac
    18601 gtgcactgca cgagctgccg ctcctgctcg agcgtcaatg gctcgaactg cacgccgaga
    18661 tgcgcggcgt cgacgcgggt cacgcgcacc ggaaaatgga acgggcgatc gccgcggctc
    18721 acgcatacgt cgagcgtatc gccgagcgcg atgcgcgcga gcggcaccgc gtcgagcccc
    18781 aagccgcccg ccgaataatc cttcgtgtgg cacgcggccg tcgtgccgtc ggcgagcaac
    18841 agcgtcgccg gcacccgcat cgcgacccgg tgcgtgacgc gcacctgttt cgcctcgcgc
    18901 gcgaccgcga gcgccgcgcc gagcatcgcg aggttgtaca acgcccacgc gacgttcatc
    18961 aggatcgtcg acgcttcgtc gccgccgctc gcggcgagac gcacgccgcc cgccgcgatc
    19021 gccgcgacgt tcagcacgaa cagcgcgaga tagggcctgg acgtcgccca gtcgacgtag
    19081 ccttcgtcga tgcgcccgcc cttcgcggtc acgttgaagc ggccgtgcct cgggctcagg
    19141 aacgcgagcg tcgtcggcag cgcgatgtac cacgcgagca tcgattcgta cacctcggcc
    19201 cagaacgaat gccgaaagcg cccctgcatc cgcgcgttcg cgacgtgcgc gagcgccatg
    19261 tacggcagca cgtagctcgc gagcgcgagc gccgacgcgt tgatgaaata cagatggaag
    19321 aacagatacg cgatcggcat cgtcaggaac acgagccgcg ggatgccgta gaagaaatgc
    19381 agcatcgcgt tgccgtagca cacgcgctgg aagaagccga ggccgcggcc gacgaacggg
    19441 ttgtcgatcc ggaagatctg cgccatcccg cgcgcccagc gcgcgcgctg ccggatgtgg
    19501 cccgcgaggc tttcggtcgc gaggccggcg gcctgcacgg tcggcagata ggcgctcgtg
    19561 tagccgcggc ggtgcagctt gagcgcggtg tgcgcatcct cggtgacggt ctcgatcgcg
    19621 acgccgccga ttgcttcgag cgggccgcgc ttgagcaccg cgcacgaacc gcagaagaac
    19681 gcggcgttcc acagatcgtt gcccgcctgc acgaggccat agaacaggct gccctcgttc
    19741 ggcacgcggc ggaacgtgcc gaggttgcgc tcgaacgggt ccggcgagaa gaaatgatgc
    19801 ggcgtctgca cgagcgcaca gttcggatcg cgaaggaacg cgcccatcgt cgtctgcagg
    19861 aacgagcgcg tcggcacgtg atcgcagtcg aagatcgcga tgtattcgcc gtgcgtgcgc
    19921 gcaagcgcgc tattgatgtt gccggccttc gcgtggcgat tgtcgtcgcg cgtcagatag
    19981 ccgatgcccg cgtcgcgcgc gaacgcctcg aactccgggc ggcggccgtc gtcgagcaga
    20041 tagacgttga gcttgtccgc cggccaatcg aggctttgcg cggcgaagat cgtcggtttc
    20101 acgaccgcga gcggctcgtt gtacgtcgga atgtagacgt cgacgctcgg ccagccggcg
    20161 ggatcgtccg gcaggcgcgc gaccgggcgc tcgagcggcc acgcggtctg cacgaagccg
    20221 agcacgagga tgagccacgt gtacgcctcg gccgcgtaca gcagatagcc gacgcacgcc
    20281 tcgaccggtg tgcgcaaatc gagcgtctcg gtgctgcgcc accagatgta gcgggccatc
    20341 gcgagcagcg cgaacgtcgc gagcgcgagc gtcggcaagc ggccgggcac gcggcgcagc
    20401 gcgagcgcga gcgcggcgag cgtcgcgaag aacgcgaact ggccggcggg cgcgagcggc
    20461 gacgtgccgg ccgcgagcca cagcgcaacg cccgccgccg cgctcgccgg caacagccag
    20521 cggcgtgcga cggcccgctg cgcgccgtgc tcgaggcgcg cgccccagcg gtgccacggc
    20581 agacgggcga gccaggcgtc gacgcgccg
//
