LOCUS       NZ_CP010954            24558 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Sphingobium sp. YBL2 chromosome, complete genome.
ACCESSION   NZ_CP010954
VERSION     NZ_CP010954.1
KEYWORDS    RefSeq.
SOURCE      Sphingobium sp. YBL2
  ORGANISM  Sphingobium sp. YBL2
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingobium.
REFERENCE   1  (bases 1 to 4766421)
  AUTHORS   Yan,X.
  TITLE     The analysis of one genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4766421)
  AUTHORS   Yan,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2015) College of Life Sciences, Nanjing
            Agriculture University, Weigang Street #1, Nanjing, Jiangsu 210000,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2014
            Assembly Method                   :: Celera Assembler v. 8.0
            Assembly Name                     :: YBL2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina MiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000943805.1-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 04:34:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,219
            CDSs (total)                      :: 5,153
            Genes (coding)                    :: 5,086
            CDSs (with protein)               :: 5,086
            Genes (RNA)                       :: 66
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 25 of 67
            Pseudo Genes (incomplete)         :: 53 of 67
            Pseudo Genes (internal stop)      :: 4 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2335598
            Orig. end                         :: 2360156
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP010954.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from yanxin@njau.edu.cn.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24558
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24558
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24558
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14558](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14558
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            68..1846
                     /locus_tag="TZ53_RS10615"
                     /old_locus_tag="TZ53_10610"
     CDS             68..1846
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004209760.1"
                     /locus_tag="TZ53_RS10615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10610"
                     /product="SLC13 family permease"
                     /protein_id="WP_044661242.1"
                     /transl_table=11
                     /translation="MHFITALIGIYRAEIGLLILALMFVAFVRERYSPTVVSVVGACVF
                     AALGLLDEKDLFSVFSNSAPLTVGAMFVLSGALIRTGTINRVADLVMARAQRHPRLALA
                     EVTLGTVILSAFLNNTPVVVLLIPIMFKLAQATGYPVKKLLIPMNAVAVMGGCVTLIGT
                     STNLIVAGIAAEQGMAPFGIFDITPYGLAGVLAGVAALTGLSFLLPGDPPSIAGEDGGN
                     VQDYLTELTLSRDSDLIGRTVGSLSIIGRSASLLGLKRAGEIRRRGIEEEELHAGDRLL
                     VHADGATIMTLRESGDFEIGLAAASETPGGGTVIEAMIAPSHPSIGERLIDIPFLHALR
                     VRIIGIHRARHLPGPDLSETRVRGADRLLIAGSDDSIRSLKDNAHLIGVDISRTRAFRP
                     RKAWIAILALTAVVLLSAVDLIGIGLAAFIAVGVILVTRCIDPEEAWAAIDGDVLILIF
                     AMLAVGLALEQAGSVALMVGWIEPLLAAAPAWTLVFLIYFFALLLSELLSNNAVAALLT
                     PLTIALAHQLGADPRPLVIALMIGASACFATPIGYQTNALVHAAGDYRFSDFVRIGIPL
                     NLIVGLAVCTTLTLLA"
     gene            1958..2746
                     /locus_tag="TZ53_RS10620"
                     /old_locus_tag="TZ53_10615"
     CDS             1958..2746
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007683138.1"
                     /locus_tag="TZ53_RS10620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10615"
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="WP_044661243.1"
                     /transl_table=11
                     /translation="MTSLPIIQVDAFADAPFTGNPAAVMPLGRWLDDATLQAIAAENNL
                     SETAFTVPTPDDPEADYALRWFTPAVEVKLCGHATLASGHVLMGGRTAVRFRTREAGIL
                     TVSRDRDGYGLSLPAWPTAPSPLPELAAAMGGDVLETQWREGGFAIFVYRDAAAIHALE
                     PDFATLKKAGPLLLIATAPGEDSDMVSRVFVPGAGIDEDPVTGSAHCLLTPYWAKRLDK
                     IRLTAFQASQRGGRLTCRLSGDRVILTGACRTVIEGNFLL"
     gene            complement(2822..3943)
                     /locus_tag="TZ53_RS10625"
                     /old_locus_tag="TZ53_10620"
     CDS             complement(2822..3943)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007683145.1"
                     /locus_tag="TZ53_RS10625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10620"
                     /product="serine hydrolase"
                     /protein_id="WP_044661244.1"
                     /transl_table=11
                     /translation="MRLERNSVKRLGMPGGILAILAVAGLWTVRAAGPEPVYHVAGDSD
                     ADAAALRAAIDPLFEDAVGETRALVVMHDGEIVAERYAPGYGPRTKLPSWSTAKSVTAV
                     LIGLMVSDGRLALDSPVPVAAWGQPGDPRGRITLRQLLAMTSGLDHVEDREPLAEADTI
                     RMLFTDGAQDMGAFAEAKPLAHAPGTAFSYSTGNSVILADLMARMLTNSTDPDVRRRAM
                     QMFIDGRLKIPARLDSLAVEYDAAGTMIGGSFMHMTARDYARFGELLRNHGRGVAGHQI
                     VPEKWIDYMRAPSPRNAAYGAHLWLNRDSEDSALMPGRAPRSLFGCVGHGGQYILVSPS
                     QRLTVVRLGMSPTKEERDALKTGLAKLVGLYSR"
     gene            3982..4296
                     /locus_tag="TZ53_RS10630"
                     /old_locus_tag="TZ53_10625"
     CDS             3982..4296
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847875.1"
                     /locus_tag="TZ53_RS10630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10625"
                     /product="hypothetical protein"
                     /protein_id="WP_044661245.1"
                     /transl_table=11
                     /translation="MSGRRKWIYGVLAVALLPLALLAWNWSALRAHAQVGAGFGARVTC
                     SCRYMEGRSMESCHGDKEPGMWAVSLKDMPESQSVNAAVPLLASRTARYRKGWGCLLEP
                     "
     gene            4381..6153
                     /gene="recQ"
                     /locus_tag="TZ53_RS10635"
                     /old_locus_tag="TZ53_10630"
     CDS             4381..6153
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recQ"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007683151.1"
                     /locus_tag="TZ53_RS10635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10630"
                     /product="DNA helicase RecQ"
                     /protein_id="WP_025551867.1"
                     /transl_table=11
                     /translation="MRPDIPTLLHDVFGFPGFRGVQEQVVSRIMAGQATLAIMPTGAGK
                     SLCYQLPAVALEGCCVVISPLIALMHDQLRAAQAVGIRAASLTSVDADWRETQDRLRNG
                     DLDLLYVAPERASGEGFRNLLRAAKIALFAIDEAHCVSEWGHDFRPDYRLLRPLLDEFP
                     DVPRLALTATADHHTRDDILVQLGIPREGLIIAGFDRPNIRYAVHPRDGLPRQLSDLIA
                     GQTGPGIVYAPTRAATEKLAETLSKTGRPTRAYHAGLDPQVRAANQAAFIASEDMVMVA
                     TIAFGMGIDKPDVRFVAHAALPKSIEGYYQESGRAGRDGEPAEAHLFWGADDFARARQR
                     IGELDPLRQQGERARITALGGLVETGTCRRAILLRHFGENPPPGCGNCDNCLNPPPSID
                     ATQTARKFLSAVYRTGQSFGVGHIEQVLTGAVTDKIRERGHDRISVYGIVDGEETALLR
                     PVSRALLVRDALQTNEHGGLEFGPNARPILRGEEEVSLVLPPRKERRRKSARNGSAENP
                     VGDPLFDALRACRRALAQEAGVPPYVIFHDSTLREMAEQRPTSLTELGHISGVGQRKLD
                     AYGDAFLAAIRPYL"
     gene            6261..6689
                     /locus_tag="TZ53_RS10640"
                     /old_locus_tag="TZ53_10635"
     CDS             6261..6689
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686872.1"
                     /locus_tag="TZ53_RS10640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10635"
                     /product="TIGR01244 family sulfur transferase"
                     /protein_id="WP_025551865.1"
                     /transl_table=11
                     /translation="MFRQLTKSLYVSPQISVDQVAEAKALGVTVIINNRPDDEEPGQTN
                     GAEIEAAARAAGIAYAAVPVAHGGFAPWQLDGMAAALEQAGEGKILAYCRSGTRSTLLW
                     ALTRARAGDHPAALTEQAASAGYDVTPVRQIMDALAAG"
     gene            6689..7873
                     /locus_tag="TZ53_RS10645"
                     /old_locus_tag="TZ53_10640"
     CDS             6689..7873
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847872.1"
                     /locus_tag="TZ53_RS10645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10640"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_044661246.1"
                     /transl_table=11
                     /translation="MASPAETYDAIVLGAGGAGLMCAAVAGQRGRRILVIDHADQAGKK
                     ILISGGGRCNFTNIHTAPDRYLSANPHFAKSALGRYTPQDFLGLVERHGIAWHEKTLGQ
                     LFCDQSARQIVAMLLAECEAGGVAIRLGHAIAAVTHADGRYCVTHGDRTATAPALVIAT
                     GGPSIPKIGATALAYDLARQFGLKVVEPRPALVPLTLGGEELLFRSLSGVSTEVIARHG
                     KTAFREAALLTHRGLSGPAILQISSYWRHGDAIALDLLPDQPQGWLTEAKRGRPRATLT
                     QCLRGHLPDRLADALAERLALPGDLGNIPDRKLQDAERRLSAWPFTPNGTEGFAKAEVT
                     IGGISTAGLSSQTMEARHLPGLYAIGEAVDVTGWLGGYNFQWAWASGWVAAQYL"
     gene            complement(8661..9656)
                     /gene="dmeF"
                     /locus_tag="TZ53_RS10655"
                     /old_locus_tag="TZ53_10650"
     CDS             complement(8661..9656)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="dmeF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686870.1"
                     /locus_tag="TZ53_RS10655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10650"
                     /product="CDF family Co(II)/Ni(II) efflux transporter DmeF"
                     /protein_id="WP_044661248.1"
                     /transl_table=11
                     /translation="MSMHDDHGHGGHHHPEGHDHVHGIPVANADDGEESHYFDHIYLTR
                     GHDENARKTIWVVWLTAATMVVEIVFGWLTGSMALLADGFHMATHAGALAVAAAAYGYA
                     RRHARNPRYTFGTGKVGDLSGFASALILAFTALFIAVESVMRFFEPVKVAFGEATLVAV
                     IGLIINLISALLLGHDHSHDHGHDHGHDHDHRHGHADNNLRAAYVHVLTDALTSVLAIM
                     ALLAGRYMGWWWLDPAVGLLGAVVIARWAWGLMKDTAAILLDTAEPALMARIKALAETE
                     GATIRDLHVWRIGPHAHAAIVSLAPGADVAAVRRQVRALPRMEHVTVECG"
     gene            complement(9653..9925)
                     /locus_tag="TZ53_RS10660"
                     /old_locus_tag="TZ53_10655"
     CDS             complement(9653..9925)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017183776.1"
                     /locus_tag="TZ53_RS10660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10655"
                     /product="metal/formaldehyde-sensitive transcriptional
                     repressor"
                     /protein_id="WP_044661249.1"
                     /transl_table=11
                     /translation="MHIVADRDKLLARVRRIAGQIGAVERQLSGDAGCSETLQLVASVR
                     GAVGSLMEELIEQHMREHVARPGISDAARETAAEEMLALIRRYGK"
     gene            10001..11161
                     /gene="crtY"
                     /locus_tag="TZ53_RS10665"
                     /old_locus_tag="TZ53_10660"
     CDS             10001..11161
                     /EC_number="5.5.1.19"
                     /GO_function="GO:0045436 - lycopene beta cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686868.1"
                     /locus_tag="TZ53_RS10665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10660"
                     /product="lycopene beta-cyclase CrtY"
                     /protein_id="WP_044661250.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 3.7e-112,
                     bitscore: 373.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATMTDCDVAIVGGGLAGSLTALALAARHPHVSLRLLESDDRLGG
                     NHIWSFFDSDVDAGDRWLVEPLIAHRWPEGYEVRFPGHCRQLAVPYNSITSARLDAHVR
                     ERLGDAVLTGAQATGLTPTSVTLSDGRVVRAKAVLDARGGGDLSALRCGWQKFVGQTLR
                     LRAPHGLSRPVVMDATVEQMDGYRFVYLLPWDERTVFVEDTYYSDTPNLDVPMLGARIA
                     AYARARDWQVEEVVHGESGVLPVVHGGDFDRFWPQDDPVARLGARAALFQPMTGYSLPD
                     AVRFALRLANEWPVEGQLLAQATRGWARDHWRQGAYYRLLGRMLFGAARPDQRWRIFER
                     FYRLDPSLIGRFYAGRSTLGDRIRILCGRPPVPIRDAMRALLSPPA"
     gene            11175..12656
                     /locus_tag="TZ53_RS10670"
                     /old_locus_tag="TZ53_10665"
     CDS             11175..12656
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017503709.1"
                     /locus_tag="TZ53_RS10670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10665"
                     /product="phytoene desaturase"
                     /protein_id="WP_025552140.1"
                     /transl_table=11
                     /translation="MNRKAIVIGAGFGGLALAIRLQSAGIDTTLVEARDRPGGRAYMWE
                     KDGFVFDAGPTVITDPDCLGELWRLSGHDMAEDVSLVPVSPFYRLNWRDGTNFDYSNDE
                     TALRAQIARLNPEDVAGYESFLDYADGVYQEGYRKLGSVAFLDFASMVRAAPALMKHQA
                     WRSVYSVVSSHVKDEKLRQALSFHTLLVGGNPMQTSSIYALIHKLEKDGGVWFAKGGTN
                     RLVQAMATHFERLGGTLRLADPVVQIETYGDRAVAVRTASGWRGEADAVASNADLMHSY
                     RDLIGHHPRGEKQAAKLARKRWSPSLFVLHFGIRGSWPGIPHHMILFGPRYEGLLTDIY
                     DYGVLPQDFSLYLHHPTVTDPSMAPEGHSTFYALAPVPHLGKLPIDWDRFAPAYAERIL
                     DEIQHRLIPDIRSRIVTRFHYAPPDFRRDLSAHLGSAFSLEPLLTQSAWFRAHNRDDVI
                     PNLYLVGAGTHPGAGIPGVVGSAKATAALMLEDLA"
     gene            12669..13250
                     /locus_tag="TZ53_RS10675"
                     /old_locus_tag="TZ53_10670"
     CDS             12669..13250
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lysine_decarbox"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020820268.1"
                     /locus_tag="TZ53_RS10675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10670"
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="WP_044661251.1"
                     /sec_met_domain="Lysine_decarbox (E-value: 3.6e-44,
                     bitscore: 148.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLAVYCGSATPADPAYVESARDVGRILAERGIGVVYGGGRLGL
                     MGAVADAALAAGGEVIGVIPEALVGAEVAHRGCTELHVVQTMHQRKQLFTDLSDGFVTL
                     PGGVGTMDELWEAISWAQLGYHRKPVGLLNVAGFYDQLIAFNQHMVEAGFIRAQHANIL
                     IHANAIEALLDRMAAYQPHETIFAMKADRL"
     gene            13605..14558
                     /locus_tag="TZ53_RS10680"
                     /old_locus_tag="TZ53_10675"
     CDS             13605..14558
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020818991.1"
                     /locus_tag="TZ53_RS10680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10675"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_044661252.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.5e-39, bitscore:
                     131.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.4e-67,
                     bitscore: 226.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSEFPDRPSLIAQARDSIARGSKSFALASRLFDRSTRERAWLLY
                     AWCRKCDDIADGQDHGGTMRGVADGQARLSTIRVLTGSALQGEPTGDPAFDGFGLVMRE
                     CAIPERYAHDLIEGFALDAREWRPRSEADMLRYCYHVAGTVGCMMAILMGVDPGDEATL
                     DRACDLGLAFQLANIARDISEDEAADRCYLPEEWLVEMDIPPGEHMKPWVRPRLAILAR
                     RMANMAAAYEESARHGTGALPPRSAWAVLAAAGIYGDIAREVARRGDHAWDHRVTTPKG
                     DKLRWVFRAGLQVPGRARRWPAGTSRPDMLWTRPRT"
     gene            complement(14660..16003)
                     /locus_tag="TZ53_RS10685"
                     /old_locus_tag="TZ53_10680"
     CDS             complement(14660..16003)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008519 - ammonium transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009822857.1"
                     /locus_tag="TZ53_RS10685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10680"
                     /product="ammonium transporter"
                     /protein_id="WP_025549956.1"
                     /transl_table=11
                     /translation="MTFSKKLSGVAGAMGLSLFAAMPAWAQAAAPAATVDKGDTAWMMT
                     STVLVLAMILPGLALFYGGLVRTKNMLSVMTQIGAVACLAMLIWVIYGYSMAFGPDYTS
                     GLSNFISTFDKAFLKGITPASQAATFTAGVEIPEYVFVSFQMTFAAITVALVLGSVVER
                     IKFSAVMVFAIVWLTIVYFPIAHMVWAASGLFFKAGALDFAGGTVVHINAGVSALVACL
                     ILGKRVGFPKEPMPPHSLTLTGVGTGLLWVGWFGFNAGSALEANGSAALAMINTFVATA
                     SAGLFWMLAERVNGHKGSALGFCSGIIAGLVAVTPAAGNSGPFGAIVLGAVASIVCFYA
                     VTVLKPKLGYDDSLDAFGIHGIGGMIGAIGTAIVYSPSLGGPGAADYDMGAKLVVQIEA
                     VLTTIVWASIGTAIAIFIAKAVTGLRVSKEVELEGLDLGEHGERAYNP"
     gene            complement(16015..16353)
                     /locus_tag="TZ53_RS10690"
                     /old_locus_tag="TZ53_10685"
     CDS             complement(16015..16353)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014074444.1"
                     /locus_tag="TZ53_RS10690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10685"
                     /product="P-II family nitrogen regulator"
                     /protein_id="WP_013847864.1"
                     /transl_table=11
                     /translation="MKLVMAIIKPFKLDDVREALSSLGIAGMTVSEVKGFGRQKGQTEI
                     YRGAEYSTNMVPKIKIEVVCDDDLAPRVVEATQAAANSGAIGDGKIFVLDVEQAVRIRT
                     GETGETAL"
     misc_feature    complement(16390..16403)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     misc_feature    16458..16474
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 24.09"
                     /tool="antismash"
     misc_feature    16487..16503
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: strong, score: 26.62"
                     /tool="antismash"
     misc_feature    complement(16490..16499)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.77"
                     /tool="antismash"
     misc_feature    16500..16513
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            complement(16629..17204)
                     /locus_tag="TZ53_RS10695"
                     /old_locus_tag="TZ53_10690"
     CDS             complement(16629..17204)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847863.1"
                     /locus_tag="TZ53_RS10695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10690"
                     /product="DUF924 family protein"
                     /protein_id="WP_044661253.1"
                     /transl_table=11
                     /translation="MNMLTDSHDAVTADWAAALLDFWFNRIGEQGWWSHDPALDRACQA
                     RFRALWEEKRHLPAEEFLERADDALAAVLLFDQLPRNMFRGSAAAFSTDPLAREVARGA
                     VAHGYDIQIGGAGRLFFYMPFQHSEARDDQKLSLSLFEGAGDEKSLAFAREHYEMIERF
                     GRFPHRNATLGRANRPGEEEAAKEGGSW"
     misc_feature    17178..17192
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            complement(17260..18702)
                     /gene="tldD"
                     /locus_tag="TZ53_RS10700"
                     /old_locus_tag="TZ53_10695"
     CDS             complement(17260..18702)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="tldD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013038833.1"
                     /locus_tag="TZ53_RS10700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10695"
                     /product="metalloprotease TldD"
                     /protein_id="WP_044661254.1"
                     /transl_table=11
                     /translation="MTDAAPQFTDARGLLYRPGLLDPDGARRLTAEALKGCDDGELYLQ
                     YRASESFGFDDGRLKTADYSTDAGFGLRGVSGEMTGFAHANDISEAAIRRAAETLTLLD
                     PAKGQPAPPPQHTNRHLYTDVNPLEIVPFAEKVTLCAAIDAAARARDPRVAQVSVSLAG
                     SWSVVEIVRADGFTATDIRPLVRLNVSVILEENGRRETGVFGIGGRYLYDEVMEPAIWN
                     RAIDEALAQARVNLRSVAAPAGEMTVLLGPGWPGVLVHEAIGHGLEGDFNRKGTSAFSG
                     RVGQRVAAPGVTVVDDGSIMSRRGSLSIDDEGTPTKENVLIEDGILKGYMQDRLNARLM
                     GVEPTGNGRRESYAHAPMPRMTNTFIKGGQDDPEELLSRMKSGIFAKSFGGGQVDIVSG
                     KFVFSCTEAYKVENGRLGEPIKGATLIGDGPTALTKVIGIGHDWALDEGIGMCGKAGQS
                     VPAGVGQPTLLMEGLTVGGTAT"
     gene            complement(19028..19255)
                     /locus_tag="TZ53_RS10705"
                     /old_locus_tag="TZ53_10700"
     CDS             complement(19028..19255)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847861.1"
                     /locus_tag="TZ53_RS10705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10700"
                     /product="zinc-finger domain-containing protein"
                     /protein_id="WP_044661255.1"
                     /transl_table=11
                     /translation="MIQPPEIIRVTKSRISCDGSGDIPAALGHPRVFLEIDEHGYIDCG
                     YCDRRFVLTGSVADTPEIAGLPDIPSGASL"
     gene            complement(19311..19484)
                     /locus_tag="TZ53_RS27140"
     CDS             complement(19311..19484)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686852.1"
                     /locus_tag="TZ53_RS27140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_165363344.1"
                     /transl_table=11
                     /translation="MSLTLLLAGTVAPFLLMFSPVSLAAARDCLDWEAPAKAVDLGVEK
                     PCPKKKPPLLLM"
     tRNA            complement(19573..19648)
                     /anticodon=(pos:complement(2355211..2355213),aa:Val,
                     seq:tac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="TZ53_RS10710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="TZ53_10705"
                     /product="tRNA-Val"
     gene            complement(19573..19648)
                     /locus_tag="TZ53_RS10710"
                     /old_locus_tag="TZ53_10705"
     gene            complement(19734..20738)
                     /locus_tag="TZ53_RS10715"
                     /old_locus_tag="TZ53_10710"
     CDS             complement(19734..20738)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013038835.1"
                     /locus_tag="TZ53_RS10715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10710"
                     /product="winged helix DNA-binding protein"
                     /protein_id="WP_172668313.1"
                     /transl_table=11
                     /translation="MGLDHDEIGFGASLDQPFGARDERPGLLILADDIYLDDAAMLSQA
                     AGLRLLGTVPLDQASTRLDVQIGCDIILCFCPTPDPMIERLLVQIETLALQNDMPVILV
                     ADLGTVDLAYACLRSERTQLLCRPGHTDLAAALLAAARQRPSESLHEANRDNEGLRLQQ
                     LSDEVSRLARTLEALTLRPRHATPSFDLGPRISDEPSDYIGMPALEPIGSADKSADAAA
                     LEAAQVRDLLRARRLRDDFLPADLFADPAWDMLLDLLAARLEHERVSVSSLCIASAVPP
                     TTALRWIRTLTEMGFVDRQADPHDGRRVFIALADHTAEALTRWFTASRRFLCA"
     gene            complement(20996..21847)
                     /locus_tag="TZ53_RS10720"
                     /old_locus_tag="TZ53_10715"
     CDS             complement(20996..21847)
                     /EC_number="2.6.1.21"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (46-274). E-value: 1.9e-35.
                     Score: 114.6. Matches aSDomain:
                     nrpspksdomains_TZ53_RS10720_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020818997.1"
                     /locus_tag="TZ53_RS10720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10715"
                     /product="D-amino-acid transaminase"
                     /protein_id="WP_044661257.1"
                     /transl_table=11
                     /translation="MSIAYLNGRFLPLEQAQLSVLDRGFLFADGIYEVAAVIDGKLVDS
                     ASHLARLERSTQAIGIALPLSLTEIEAAQKELVARNALAEGLVYLQITRGADATRDFLP
                     SPGIQPTLVMFVQAKPFLDVPAVRNGIAVATMPDLRWARRDIKSVGLLAQAMAKRAAAE
                     AGAQEAWMVEDGFVTEGASSTAFIVTEEGIVTRPYSQAVLAGCTGAALTALAEESGIAI
                     VRRPFTVAEALAAKEAFITSASTLCQSVVRIDGRAIGDGKPGPLAMRLRALYIDFARRT
                     AV"
     aSDomain        complement(21026..21709)
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TZ53_RS10720_Aminotran_4.1"
                     /evalue="1.90E-35"
                     /label="TZ53_RS10720_Aminotran_4.1"
                     /locus_tag="TZ53_RS10720"
                     /protein_end="274"
                     /protein_start="46"
                     /score="114.6"
                     /tool="antismash"
                     /translation="SHLARLERSTQAIGIALPLSLTEIEAAQKELVARNALAEGLVYLQ
                     ITRGADATRDFLPSPGIQPTLVMFVQAKPFLDVPAVRNGIAVATMPDLRWARRDIKSVG
                     LLAQAMAKRAAAEAGAQEAWMVEDGFVTEGASSTAFIVTEEGIVTRPYSQAVLAGCTGA
                     ALTALAEESGIAIVRRPFTVAEALAAKEAFITSASTLCQSVVRIDGRAIGDGKPGPLAM
                     RLRALY"
     gene            complement(22009..23523)
                     /gene="rpoN"
                     /locus_tag="TZ53_RS10725"
                     /old_locus_tag="TZ53_10720"
     CDS             complement(22009..23523)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpoN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020818998.1"
                     /locus_tag="TZ53_RS10725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10720"
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="WP_044661258.1"
                     /transl_table=11
                     /translation="MALAPRLDLRQSQSLVMTPQLQQAIKLLALSNLEIEAFVAGELEK
                     NPLLESGGADDFAPPADGVDRAAEQHDLRAETGDADQLIGQGLGGADSPLDVDYSAETF
                     IDDGPGDRMATAAIGSGGMDLLSGGSGEAPDFDSFANPEQGLQEHLMDQARSALSGMDL
                     MIAAQLIGQIDEAGYLEANLLETAHGMGVPLFQVEQVLAVIQAFDPTGVGARSLSECLA
                     LQAKEVDRYDPCMAKLLANLDLLAKGALPQLRRICGVDEEDMADMIRELRDYDPKPGLR
                     FSTESAAPVTPDLFVRPTREGWAIEVNSATLPRVLINRTYYVELASGPQDKTSKAWLAD
                     CLASANWLVKALDQRQKTIIKVASEIVRQQEDFFRKGVEHLKPLTLKAVADAIQMHEST
                     VSRVTSNKYLSCPRGLYELKYFFTSGVSAAGGDGAVSAEAVKSHIKALIAAETPDAILS
                     DDTLVDLLRAKGMDIARRTVAKYREAMGIGSSVQRRRQKALRGQAA"
     gene            complement(23572..24357)
                     /gene="lptB"
                     /locus_tag="TZ53_RS10730"
                     /old_locus_tag="TZ53_10725"
     CDS             complement(23572..24357)
                     /EC_number="7.5.2.5"
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lptB"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007709503.1"
                     /locus_tag="TZ53_RS10730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_10725"
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="WP_025549950.1"
                     /transl_table=11
                     /translation="MDDVMMQDRSAPASPLPPQEVGEGLSVISIAKSYDKRVVLADVSL
                     TVGKGEVVGLLGPNGAGKTTCFYSVMGLVRPDHGRIVLDGQDITGLPMYRRSILGLGYL
                     PQETSIFRGLTVAQNIGAVLELAEPDRAARQARLEQLLEEFGLTRLRDSSAMALSGGER
                     RRCEIARALAANPSIVLLDEPFAGIDPLSIADIRDLVKQLKTRGIGVLITDHNVRETLE
                     IVDRACIIYDGKVLFAGSPTELVANADVRRLYLGENFSL"
ORIGIN
        1 gccatgcaac catggctggc ccatttcgtt caggcaggac gcgaaaacgc gatccggggc
       61 acaaggcatg catttcatca ccgcgctgat cggcatctat cgcgcggaaa tcggacttct
      121 catcctcgcc ctgatgttcg tcgccttcgt gcgcgaacgc tattcgccca cggtcgtctc
      181 cgtggtcggg gcgtgcgtgt tcgcggcgct gggcctgctc gacgaaaagg acctgttctc
      241 cgtcttctcc aacagtgcgc cgctgacggt gggcgcgatg ttcgtgcttt ccggcgcgct
      301 gatccgcacg gggacgatca atcgcgttgc cgacctggtc atggcccgcg cccagcgcca
      361 cccgcgcctg gcgctggccg aagtcacgct cggcacggtc atcctctcgg ccttcctcaa
      421 caacacgccc gtggtggtgc tgctgatccc gatcatgttc aagctggcgc aggcgaccgg
      481 ctatccggtg aagaagctgc tgatcccgat gaacgccgtt gccgtgatgg gcggttgcgt
      541 gacgctgatc ggcacatcga ccaacctgat cgtcgcaggc atcgccgccg agcagggcat
      601 ggcgcccttc ggcatattcg acatcacgcc ctatgggctg gcgggggtct tggccggcgt
      661 cgccgcgctg accggcctgt ccttcctgct tcccggcgat ccgccctcca tcgcggggga
      721 ggatggcggc aatgtgcagg attatctgac cgaactcacc ctgtcgcgcg acagcgacct
      781 catcggccgc acggtcggct ccctgtcgat catcggccgc tccgccagcc tgctcggcct
      841 caagagggcg ggggagatac ggcgccgggg gatagaggaa gaggaactgc acgccggcga
      901 ccgcctgctg gtccatgccg acggcgcgac gatcatgacc ctgcgcgaat ccggcgattt
      961 cgaaatcggg ctggccgcgg cgtcggagac tccgggcggc ggcaccgtca tcgaagcgat
     1021 gatcgcgccc agccatccgt ccatcgggga acggctgatc gacattccct tcctgcacgc
     1081 gctgcgggtg cggatcatcg gcatccaccg ggcgcgtcac ctgccgggtc cggacctcag
     1141 cgaaacccgc gtgcgcggcg ccgaccgcct gctgatcgcg ggcagcgacg acagcatccg
     1201 ttcgctcaag gacaatgccc atctgatcgg cgtcgacatc agccgcaccc gcgccttccg
     1261 cccgcgaaag gcatggatcg ccattcttgc cctgacggcg gtggtgctgc tctcggccgt
     1321 cgatctcatc ggcatcggcc ttgccgcctt catcgccgtg ggcgtgatcc tcgtcacccg
     1381 ctgcatcgac ccggaggaag cctgggccgc catcgacggc gacgtgctga tcctgatctt
     1441 cgccatgctc gcggtcgggc tggcgctcga acaggcgggc agcgtcgcgc tgatggtcgg
     1501 ctggatcgag ccgctgctcg ccgccgctcc ggcatggacg ctggtgttcc tcatctattt
     1561 cttcgcgctt ctgctgtcgg aactgctcag caacaatgcg gttgcggcgc tgctcacgcc
     1621 gctcaccatc gcgctcgccc atcaactcgg cgctgatccg cgtccgctgg tgatcgcgct
     1681 gatgatcggc gcgtcggcct gcttcgccac gccgatcggt tatcagacca acgcgctcgt
     1741 ccatgcggcg ggcgactatc gcttttccga tttcgtgcgc atcgggattc cgctcaacct
     1801 gatcgtcgga ctggcggtct gcaccacgct cacccttctg gcttgaggag cgggcctggc
     1861 ctgaggagcc gggcgacgcc aagccatttt cggcggaccg gccctgtccc cgcatcgaac
     1921 gcatcgtcat gatggcccga aaaccaaagg attgcccgtg accagcctgc ccatcattca
     1981 ggtcgacgcc ttcgccgacg ctcccttcac cggcaatccg gccgcggtca tgccgctcgg
     2041 ccgatggctg gacgatgcga cgcttcaggc gatagcggcg gaaaataatc tgtccgaaac
     2101 cgccttcacc gtgcccacgc ccgacgatcc ggaggcggac tatgcgctgc gctggttcac
     2161 gcccgccgtg gaggtcaagc tctgcggcca cgccacgctg gcgagcggcc atgtgctgat
     2221 gggcgggcgt accgccgtcc gcttccgcac gcgggaagcg ggcatcctga ccgtgtcgcg
     2281 ggaccgcgac ggctatggcc tctcgctccc ggcctggccg accgcgccca gcccgctgcc
     2341 ggagctggcg gcggcgatgg gcggggacgt cctcgaaacc cagtggcgcg agggcggctt
     2401 cgcgatcttc gtctatcgcg atgccgccgc gatccatgcg ctggaaccgg acttcgcgac
     2461 gctgaagaag gcggggcccc tgctgctcat cgccaccgca cccggcgagg acagcgacat
     2521 ggtgagccgc gtcttcgttc ctggcgcggg catagacgaa gacccggtga ccggctccgc
     2581 ccattgcctg ctcacgccct attgggcgaa gcggctcgac aagatcaggc tgacggcatt
     2641 tcaggcatcg cagcgcggcg ggcgcttaac gtgccggctt tcaggcgacc gggtgatcct
     2701 gacgggcgcc tgccgcacgg tgatcgaagg caatttcctg ctttgagagg tggcgatggc
     2761 tgaggccgtc cggccaattc cagccaaccg gcggccctgc gcaaagaaaa tagaggtcag
     2821 ttcaccgcga ataaagcccg acgagcttcg ccagccccgt cttcagcgca tcgcgctcct
     2881 ccttcgtggg cgacatgccc agccgcacga ccgtcaggcg ctgcgaaggc gaaaccagta
     2941 tatattgccc gccatgcccg acgcagccga acaggctgcg cggcgcccgc cccggcatca
     3001 gcgcgctgtc ctcgctgtcc cggttcagcc acagatgcgc gccataggcg gcattgcggg
     3061 gcgagggcgc gcgcatatag tcgatccact tttccggcac gatctgatgc cccgccacgc
     3121 cgcgcccgtg attgcgcagc aattccccga agcgggcata atcccgcgcc gtcatatgca
     3181 tgaagctgcc gccgatcatc gtcccggccg catcatattc caccgccaag ctgtcgaggc
     3241 gcgccggaat cttcagccgc ccgtcgatga acatctgcat cgcccgccgc cgcacgtcgg
     3301 gatcggtgct gttggtcagc atccgcgcca tcaggtcggc caggatgacg ctgttgccgg
     3361 tcgaatagga aaaggcggtc ccaggcgcat gggcaagcgg cttggcctcc gcaaaggcgc
     3421 ccatgtcctg cgctccgtcg gtgaacagca tccttatcgt gtcggcctcc gccagcggtt
     3481 ccctgtcctc gacatgatcg aggcccgacg tcatggccag caactgccgc agggtgatgc
     3541 gccctcgcgg atcgcccggc tgcccccagg ccgcgaccgg caccggcgaa tcgagcgcca
     3601 gccgcccgtc cgacaccatc agcccgatca gcaccgccgt cacgctcttg gccgtggacc
     3661 aggacggcag cttcgtccgc ggcccatagc ccggcgcata gcgctccgcc acgatttcgc
     3721 catcgtgcat gacgaccagc gcccgggtct cgcccaccgc atcctcgaac aaaggatcga
     3781 tggccgcgcg cagggcggcg gcgtccgcgt ccgaatcgcc tgcgacatgg tagaccggct
     3841 ccggcccggc ggcgcgcacc gtccacaacc cggccacggc cagaatcgcc aaaatcccgc
     3901 ccggcatgcc aaggcgcttt acgctgttcc gctcaagcct cataagccgc ggccttagca
     3961 tggagcgcgg gaaaggggag catgtccggt cgccggaaat ggatttatgg ggttttggcg
     4021 gtggccctgc tgccgctggc gctactggcg tggaactgga gcgcccttcg cgcccatgcc
     4081 caggtcggcg cgggcttcgg cgcgcgcgtc acctgctcct gccgctatat ggaaggccgg
     4141 tcgatggaaa gctgtcatgg cgacaaggaa cccggcatgt gggccgtgtc gctgaaggac
     4201 atgcccgaat cgcaatcggt caacgcggcg gttccgctgc tcgcttcgcg cacggcgcgc
     4261 tatcgcaagg gctggggctg tctgctggag ccttgagctt ccatggtcat cccggctttc
     4321 gctgggatga ccatgtggga agctggcccc aatcccctca aagcgctaca gccccttccc
     4381 atgcgtcctg acatcccgac cctcctccac gatgttttcg gctttcccgg cttcaggggc
     4441 gtgcaggaac aggtggtcag ccgcatcatg gcggggcagg cgacgctggc gatcatgccg
     4501 accggcgcgg gcaagtctct ctgctaccag cttcccgccg tcgcgctcga aggctgctgc
     4561 gtcgtcatat cgccgctgat cgcgttgatg cacgaccagc ttcgcgccgc gcaggcggtc
     4621 ggcatccgcg ccgccagcct caccagcgtc gacgccgact ggcgcgagac gcaggaccgg
     4681 ctgcgcaatg gcgatctcga cctgctctat gtcgcgccgg agcgcgccag cggggagggg
     4741 ttccgcaacc tcctgcgcgc cgcgaagatc gccctcttcg cgatagacga agcccattgc
     4801 gtctccgaat ggggccatga tttccgcccg gactatcgcc tgctgcgccc gctgctcgat
     4861 gaatttccgg acgttccccg tctcgcactg accgcgaccg ccgaccacca cacccgcgac
     4921 gacatccttg tccagcttgg cattccccgc gaaggcctga tcatcgcggg cttcgaccgt
     4981 ccgaacatcc gctacgccgt ccatccccgc gatggcctgc cccgccagct ttccgacctg
     5041 atcgccggcc agaccggccc cggcatcgtc tacgccccca cccgcgccgc gaccgagaag
     5101 ctggccgaaa ccctcagcaa gaccggccgc ccgacccgcg cctatcatgc cgggctcgac
     5161 ccgcaggtcc gcgccgccaa ccaggccgcc ttcatcgcca gcgaggatat ggtgatggtc
     5221 gcgaccatcg ccttcggcat gggcatcgac aagcccgacg tccgcttcgt cgcccatgcg
     5281 gcgctgccca agtcgatcga gggctattat caggaatccg gccgcgcagg ccgcgacgga
     5341 gaacccgccg aagcgcatct tttctggggc gccgacgatt tcgcccgcgc ccggcagcgc
     5401 atcggcgagc tcgatcccct gcgccagcag ggcgagcgcg cccgcatcac cgcgctgggc
     5461 gggctggtcg aaaccggcac ctgccgccgc gccatattgc tccgccattt cggggaaaat
     5521 cccccgccgg gctgcggcaa ttgcgacaat tgcctcaatc cgccgcccag catcgacgcg
     5581 acccagaccg cgcgcaaatt cctgtccgcc gtttaccgca ccggccagag cttcggcgtc
     5641 ggccatatcg agcaggtgct gaccggcgcc gtcaccgaca agattcgcga acgcggccat
     5701 gacaggattt cggtctacgg catcgtcgac ggagaggaga cggcgttgct gcgccccgtc
     5761 tcccgcgccc tgctggtgcg cgacgcgctc cagaccaacg agcatggcgg gctggaattc
     5821 ggccccaatg cccgcccgat cctgcgcggg gaggaagagg tcagcctggt cctcccgccc
     5881 cgcaaggaac gccgccgcaa gagcgcccgc aacggcagcg cggaaaatcc ggtgggcgat
     5941 ccgctgttcg acgccctgcg cgcctgccgc cgcgcactgg cgcaggaggc gggcgtgccg
     6001 ccctatgtga tcttccacga ttcgaccctg cgtgaaatgg cggagcagcg cccgacgagc
     6061 ctcacggaac tcggccacat cagcggcgtg ggacagcgca agctcgacgc ctatggcgac
     6121 gccttcctcg cggcgatccg cccttatctt tagaacggaa gaattgacct gctcctgcga
     6181 aggagcatgc tgctctgtag cctaccctct tgaatcccgc cgcccacaag cgcaaggaga
     6241 cccgaaaagg agtcccgccc atgttccgcc agctcaccaa aagcctctac gtctccccac
     6301 agatcagcgt cgatcaggtg gcggaagcca aggcgctggg cgtgacggtg atcatcaaca
     6361 accgccccga cgacgaggag ccgggccaga ccaacggcgc ggagatcgaa gccgcagcca
     6421 gggccgccgg catcgcctat gccgccgtcc ccgtggccca tggcggcttc gcgccctggc
     6481 agctcgacgg catggccgcc gcgctggagc aggcgggcga gggcaagata ctcgcctatt
     6541 gccgttccgg cacgcgcagc accttgctct gggcgctgac ccgcgcccgc gcgggcgacc
     6601 atccggcggc gctgaccgag caggccgcct ccgccggcta tgacgtcacg cccgtccgcc
     6661 agatcatgga cgcgctcgcc gccggttgat ggcttcccca gcggaaacct atgacgccat
     6721 cgtcctgggc gctggcggcg ctggcctgat gtgcgcggcc gtggcgggcc agcggggcag
     6781 gcgcatcctc gtcatcgacc atgccgacca ggcagggaag aaaatcctga tttccggcgg
     6841 cggccgctgc aacttcacca atatccacac cgcgcccgac cgctacctgt ccgccaaccc
     6901 tcatttcgcc aaatcggcgc tgggccgcta cacgccgcaa gatttcctcg ggcttgtcga
     6961 acgccacggc atcgcctggc acgaaaagac tctgggccag ctcttctgcg accagagcgc
     7021 gcgccagatc gtcgccatgc tgctggccga atgcgaggcg ggcggcgtcg cgatccggct
     7081 cggccacgcc atcgccgccg tcacccatgc cgacggccgg tactgcgtca cccatggcga
     7141 caggaccgcc acggccccgg cgctggtcat cgccaccggc ggcccctcca tccccaagat
     7201 cggcgcaacc gcccttgcct atgacctcgc ccgccagttc gggctcaagg tggtggaacc
     7261 ccgaccggcg ctggtgcccc tgaccctcgg cggcgaagag ctgctcttcc gctcgctctc
     7321 cggcgtctcg accgaggtca tcgcccgcca tggcaagacc gccttccgcg aagccgcgct
     7381 gctcacccac cggggcctat ccggcccggc gatcctgcag atttcatcct attggcggca
     7441 tggcgatgcc atcgctctcg acctcctgcc cgaccagccg caaggctggc tgacggaggc
     7501 gaagcgcggc aggccgcgcg ccacgctgac gcaatgcctg cgcggccacc tgcccgaccg
     7561 tctggccgac gccttggcgg agcggctggc gcttcccggc gacctgggca acatcccgga
     7621 tcgcaagctg caggacgccg aacgccgcct gtcggcctgg cccttcacgc ccaatggcac
     7681 cgaaggcttc gccaaggcgg aggtcacaat cggcggcatt tcgaccgcgg gattgtcctc
     7741 gcaaacgatg gaagcgcgcc acctgcccgg cctttacgcc ataggggaag cggtcgacgt
     7801 caccggctgg ctgggcggct ataatttcca atgggcctgg gcgagcggct gggtagcggc
     7861 ccaatatctc tagagcgcgc tgcgttacat cagacgcagg ccgcgcgctc taagcttttg
     7921 ttgccgcatc gtttaagcgc aaaaccggtt cccacttttg cgcacgatgc tcttaaaaaa
     7981 gcagccccgg cgcaagggaa cgccggggcc acaaagaggg atgtcccggc gggagggggg
     8041 agaaggccgg gacaagaggg aaataggaag agctatttca gtttcaagat gctacggaga
     8101 attttcttcg ggctgatgcg tctacttcgc gcctcacaat ggctgatagg gaacagtcgc
     8161 cattcaaacc ccatcatgag gatggagcca gcgccggtca tccccgcctt ggcttcaaca
     8221 tcgaccgagc gtcaggatat ctccctatgc atttccgccg gagccgaccc gaacgccatc
     8281 agagccgcat tgatcatctg ccggtgggcg tcgcttcccc ttgccacatc ccgccaatcc
     8341 tgcccggtca tcgatccatg actgtcctgc cagattttgg aggcgaccga gtccacttca
     8401 tcggcggtgg gccttcgctg ttcagcgaaa cattccatca agagggcgtg aaaaaccttt
     8461 cccgcaaagg gctttgcaac cggcataaag cctcctctcc gacggtattt tatagatttc
     8521 cgtaagggaa attgaatggc cgcccgagtc gagtcaagcc atgccgatct gccatcgtgg
     8581 tgaatttccg ccttaacccg gcggtttcgc tgctctaact cttaaggatt atctcttcgg
     8641 tagcggagtc tgcgggctgg ctatccgcac tccaccgtca catgctccat gcgcggcagg
     8701 gcgcggacct ggcggcgcac ggcggcgaca tcggcgccgg gggccaggct gacgatcgcg
     8761 gcatgggcat gcggcccgat gcgccagaca tgcaggtcgc ggatggtcgc cccttccgtc
     8821 tcggccagcg ccttgatccg cgccatcagc gccggttcgg ccgtgtcgag caggatcgcg
     8881 gcggtatcct tcatcagccc ccaggcccag cgcgcgatca ccaccgcgcc cagcaggccg
     8941 acggcggggt ccagccacca ccagcccata tagcgccccg ccagcaacgc catgatcgcc
     9001 agcaccgacg tcagcgcgtc ggtcagcaca tgcacatagg cggcgcgcag attattgtcg
     9061 gcatggccat gcctgtgatc atgatcatgc ccgtgatcat gcccgtgatc atggctatgg
     9121 tcgtgtccca gcagcagggc gctgatcagg ttgatgatca ggccgatcac cgcgaccagc
     9181 gtcgcttcgc caaaggccac cttcaccggt tcgaagaagc gcatcacgga ctcgacggcg
     9241 atgaacaggg cggtgaaggc caggatcagc gcggatgcga agccggacag gtcgcccacc
     9301 ttgcctgtcc cgaacgtata gcgcgggttg cgcgcatgcc gccgggcata gccataggcg
     9361 gcggccgcca ccgccagcgc gccggcatgg gtcgccatgt ggaagccgtc ggccagcagc
     9421 gccatcgacc cggtcagcca gccgaagacg atctcgacca ccatggtcgc cgcggtcagc
     9481 cacaccaccc agatcgtctt gcgggcattc tcgtcatgtc cgcgcgtcag gtagatatgg
     9541 tcgaaataat ggctttcctc gccatcatcc gcattggcca ccggaatgcc atgcacatga
     9601 tcatggccct cgggatgatg gtggccgcca tggccatggt cgtcgtgcat gctcatttcc
     9661 cgtagcgccg gatcagcgcc agcatttcct ccgccgcggt ctctcgcgct gcgtcgctga
     9721 tgcccggccg ggcgacatgt tcgcgcatat gctgctcgat caattcttcc atcaggctgc
     9781 cgaccgcacc ccgcacggag gcgacgagtt gcagcgtttc cgaacaaccc gcatcgcccg
     9841 acaattgccg ttctacggcg ccgatctgcc ccgcgatgcg ccgcacccgc gccagcagct
     9901 tgtcccgatc cgccacgata tgcatagggt acccccctat actatgccgg tgtgaaaatc
     9961 aatccgtgca tttccccgcg cagcccctaa caagggtgcg atggcgacca tgaccgattg
    10021 cgacgtggcg atagtgggcg gcggccttgc cggcagcctg accgcgctcg ccctcgcggc
    10081 gcgccacccg catgtctccc tgcgcctgct ggaaagcgac gatcggctgg gcggcaatca
    10141 tatctggtcc ttcttcgaca gcgacgttga cgccggggac cgctggctgg tcgagcccct
    10201 gatcgcccat cgctggccgg agggttatga ggtccgcttc cccggccact gccgccaact
    10261 tgccgtgcct tataacagca tcacctcggc gcgcctcgac gcccatgtcc gggagcggct
    10321 tggcgatgcc gtgctgaccg gcgcgcaggc caccgggctg acgcccacca gcgtcaccct
    10381 gtccgacggc cgcgtcgtcc gcgccaaggc cgtgctcgac gccagagggg gcggcgatct
    10441 ttccgccctg cggtgcggct ggcagaaatt cgtcggccag accctgcgcc tccgtgcccc
    10501 gcacggcctt tcccgtccgg tcgtcatgga cgccacggtc gagcagatgg acggctatcg
    10561 cttcgtctat ctgctgccct gggacgaacg gaccgtcttc gtcgaggata cttattatag
    10621 cgacacgccg aacctcgacg tgcccatgct cggcgcccgg atcgccgcct atgcgcgggc
    10681 gcgggactgg caggtggagg aggtcgtcca tggcgaaagc ggcgtccttc cggtcgtcca
    10741 cggcggcgat ttcgaccgct tctggccgca ggacgatccg gtcgcgcggc tgggggcaag
    10801 ggcggcgcta ttccagccca tgaccggcta ttccctgccc gatgcggtgc gcttcgcgct
    10861 gcgcctggcg aatgaatggc cggtggaggg gcaactgctc gcccaggcca cgcgcggttg
    10921 ggcgcgggac cattggcggc agggcgctta ttaccggttg ctcggccgca tgctgttcgg
    10981 cgcggccaga ccggaccagc gctggcgcat cttcgaacgt ttctatcggc ttgatccctc
    11041 ccttatcggc cgcttctatg cgggccgctc gacgctcggg gatcgcatcc gcatcttgtg
    11101 cgggcggccc cccgtgccca taagggacgc catgcgcgcc ctgttgagcc ctcccgcctg
    11161 atgaaccgga cccgatgaac cggaaagcga tcgtcatcgg cgcgggcttc ggcggccttg
    11221 cgctggccat ccgcctgcaa tccgccggaa tcgacaccac tctggtcgag gcgcgcgacc
    11281 gtccgggggg ccgcgcctat atgtgggaaa aggacggctt cgtcttcgac gccgggccga
    11341 ccgtcatcac cgatcccgat tgcctgggcg agttgtggcg cctttcgggc cacgacatgg
    11401 cggaggatgt cagcctcgtc cccgtctccc ccttctaccg gctcaactgg cgcgacggca
    11461 cgaatttcga ctattccaac gacgaaaccg ccctccgcgc ccagatcgcc cggctcaatc
    11521 cggaggatgt cgcgggctat gaaagcttcc tcgactatgc cgacggcgtt tatcaggagg
    11581 ggtatcgcaa gctcggctcg gtcgccttcc tcgacttcgc ctccatggtc cgcgccgcgc
    11641 ccgcgctgat gaagcatcag gcgtggcgct ccgtctattc cgtggtttcc tctcatgtga
    11701 aggatgagaa gctgcggcag gcgctctcct tccacacgtt gctggtcggc ggcaatccga
    11761 tgcagaccag ctcgatctac gccctgatcc acaagctgga gaaggatggc ggcgtctggt
    11821 tcgccaaggg cggcaccaac cgcctcgtcc aggcgatggc cacgcatttc gagcggctgg
    11881 gcggcacgct gcgcctcgcc gatccggtgg tgcagatcga aacctatggc gaccgcgccg
    11941 tcgccgtgcg caccgcttcg ggctggcggg gggaggcgga tgccgtcgcc tccaacgccg
    12001 acctgatgca cagctatcgc gacctgatcg gccatcatcc caggggcgag aaacaggcgg
    12061 cgaagcttgc ccgcaagcgc tggtcgccca gcctgttcgt gctgcatttc ggcatccggg
    12121 gaagctggcc gggcatcccg caccatatga tcctgttcgg cccgcgctat gaagggctgc
    12181 tgaccgacat ctatgattat ggcgtgttgc cgcaggattt ttcgctctac ctgcaccatc
    12241 cgaccgtcac cgaccccagc atggcgccgg agggccattc gaccttctac gcgcttgccc
    12301 cggtgccgca tctgggcaag ctgcctatcg attgggaccg tttcgcgccg gcctatgcgg
    12361 aacgtatcct agacgagatc cagcatcgcc tgattccgga catccgctcg cgcattgtga
    12421 cgcggttcca ttatgcgccg ccagactttc gtcgcgacct gtcggcgcat ctgggcagcg
    12481 cattcagcct ggagccgctg ttgacccaga gcgcctggtt ccgcgcgcat aatcgcgacg
    12541 acgtcattcc caacctctat ctggtagggg cgggcacgca tccgggggcg ggcattcccg
    12601 gcgtggtcgg cagcgccaag gcgacggccg cattgatgct ggaagacctg gcctgacatg
    12661 aaggatttat gaagagactg gctgtctatt gcggctcggc caccccggcc gatcccgcct
    12721 atgtcgaatc tgcccgcgat gtcggacgca tcctagccga acggggcatc ggcgtcgtct
    12781 atggcggtgg ccggctggga ctgatgggcg cggtggccga cgcggcgctg gcagcgggcg
    12841 gcgaagtgat cggcgtcatc cccgaagcgc tggtcggggc cgaagtcgcc catcgcggct
    12901 gcacggaact gcacgtcgtc cagaccatgc accagcgcaa gcagcttttc accgacctgt
    12961 ccgacggctt cgtgaccttg ccgggcggcg tcggcacgat ggatgaattg tgggaagcga
    13021 tcagttgggc gcagctcggc tatcaccgca agccggtcgg cctgctcaat gtcgcgggct
    13081 tctatgacca actcatcgct ttcaaccagc atatggtgga ggcgggcttc atccgcgcgc
    13141 aacacgccaa tatcctgatc catgccaacg cgatcgaggc attgctcgac aggatggcgg
    13201 cctatcagcc gcatgaaacc atcttcgcga tgaaggcgga tcggttgtga tcccatagca
    13261 ggacccgttc cgagaaacgg gaagcgctga gccacgctgc ggacaaattc ggaatgccgg
    13321 gaaatggcca attcaggaca ttcccctccc gtaaacggga ggggttaggg gtgggcgcga
    13381 gcgtagcgag cttctgactt agccgttgca aaacggcgca gatgccgcgc cagcccaccc
    13441 cctaaccccc tcccgcctgc gggaggggga atgtccgcaa tccacccaaa tcacccaatc
    13501 cggcgagtct tgaatttgtc cacgccggat agccgtttct caacttcgct cgaaatgaac
    13561 ggaggtcggg tgactttggc gcctgcgcag ggcatgtcct gaccatgtcc tccgaatttc
    13621 ctgaccgccc ctccctcatc gcccaggctc gcgacagcat cgccaggggt tccaaatcct
    13681 ttgcgctcgc ttccagactc ttcgaccgtt ccacccgcga acgggcatgg ctgctctacg
    13741 cctggtgccg caaatgcgac gacatcgcgg acgggcagga ccatggcggc acgatgcgcg
    13801 gcgtcgcgga cggtcaggcg cgcctctcca ccatccgcgt gctgaccggt tcggcgcttc
    13861 agggcgaacc caccggcgat ccggccttcg acggcttcgg cctcgtcatg cgcgaatgcg
    13921 cgattccgga gcgctacgct catgacctga tcgaaggctt cgccctcgac gcacgcgaat
    13981 ggcgcccgcg cagcgaggcg gacatgctgc gctactgcta ccatgtggcg ggcacggtcg
    14041 gctgcatgat ggcgatcctg atgggcgtcg atcccggcga cgaagccacg ctcgaccgcg
    14101 cctgcgactt gggccttgcc ttccagctcg ccaatatcgc ccgcgacatc agcgaggatg
    14161 aggccgccga ccgctgctac ctgccggagg aatggctggt cgaaatggac atcccgccgg
    14221 gcgagcatat gaagccgtgg gtccgcccgc gcctcgccat ccttgcccgt cgcatggcca
    14281 acatggccgc cgcctatgag gaaagcgccc gccacggcac cggcgccctg ccgccgcgat
    14341 ccgcctgggc ggtcctcgcc gccgccggca tctatggcga catcgcccga gaagtggcgc
    14401 gccggggcga ccatgcctgg gaccatcgcg tcaccacgcc gaaaggcgac aagctccgct
    14461 gggtctttcg cgcgggcctt caggtgccgg gccgcgcccg ccgctggccc gccggaacat
    14521 cgcggccgga catgctctgg acccgccccc ggacctgaca aaaaaaggga ccgatacttg
    14581 cgcatcggtc ccaaggcatg ttcgcaggag gaacaaggtg gggcgggcgg gccgtcctta
    14641 ccggcccgcc ctgccaaact tacgggttgt aggcgcgctc gccatgttcg ccgaggtcga
    14701 ggccttccag ttcgacctcc ttgctgacgc gcaggccagt gaccgccttg gcgatgaaga
    14761 tggcgatggc ggtgccgatc gacgcccaga cgatggtggt caggaccgct tcgatctgga
    14821 cgaccagctt ggcgcccatg tcatagtccg cagcgcccgg accgcccagc gagggcgagt
    14881 agacgatggc ggtgccgatg gcgccgatca tgccgccgat gccgtggatg ccgaaggcgt
    14941 ccagcgagtc gtcatagccg agcttcggct tgaggacggt gacggcatag aagcagacga
    15001 tcgaagcgac ggcgcccagg acgatcgcgc cgaagggtcc ggaattgccg gcggccgggg
    15061 tgacggcgac cagaccggcg atgatgcccg aacagaagcc cagggccgaa cccttgtggc
    15121 cgttgacgcg ctcggcaagc atccagaaca gaccggccga ggcggtggcg acgaaggtgt
    15181 tgatcatcgc gagagcggcc gagccattgg cttccagcgc cgaaccggcg ttgaagccga
    15241 accagccgac ccacagcagg ccggtgccga caccggtcag cgtcaggctg tgcggcggca
    15301 tcggttcctt ggggaagccc acgcgcttgc ccagaatgag gcaggcgacc agcgccgaga
    15361 cgccggcgtt gatgtgcacc acggtgccgc ccgcgaagtc cagcgcgcca gccttgaaga
    15421 acaggccact cgccgcccag accatgtgcg cgatcgggaa gtagacgatg gtcagccaca
    15481 cgatggcgaa caccatcacg gccgagaatt tgatgcgctc gaccaccgaa cccagcacca
    15541 gcgccacggt gatcgcggca aaggtcatct ggaagctgac gaacacatat tcggggattt
    15601 cgacgcccgc ggtgaaggtc gccgcctgcg atgcgggcgt gatgcccttc aggaaggcct
    15661 tgtcgaaggt cgagatgaag ttgctgaggc cgctggtgta atccgggccg aacgccatgg
    15721 aatagccgta gatcacccag atcagcatgg cgaggcaggc cacggcgccg atctgcgtca
    15781 tgaccgacag catgttcttt gtgcggacca ggccgccata gaacagcgcc aggccgggca
    15841 ggatcatcgc cagcaccagg accgtggagg tcatcatcca ggccgtatcg cccttgtcga
    15901 cggtggccgc gggcgcggcg gcctgtgccc aggcgggcat cgcggcgaac agcgacaggc
    15961 ccatggcccc cgcgacgccg ctaagcttct tggaaaaggt cattaattcc ccccttacag
    16021 agcggtttcg ccggtttcgc cggtgcggat gcgcactgcc tgctcgacat cgagaacgaa
    16081 gatcttgcca tcgccgatgg cgccggaatt ggcggcggcc tgggtggctt ccacgacgcg
    16141 cggcgcgagg tcgtcgtcgc agaccacctc gatcttgatc ttcggaacca tgttggtcga
    16201 atattcggcg ccgcgataga tttcggtctg ccccttctgg cggccgaagc ccttcacttc
    16261 gctcaccgtc atgccggcga tgccgagcga ggaaagtgcc tcgcggacat cgtcaagctt
    16321 gaacggcttg atgatagcca tgacaagttt catgtcgccc cctgttactg gtgtgcgaca
    16381 aactactcag caagaggcgt gccaattcgt aaaaggcggg ttaatgcggg cttttgatgc
    16441 ggtgcgtcaa aacagggcgc tgaaaaaatg ggcagcgcca ggacgatgct taaaaattag
    16501 gcacggccgt tgcctatgat caggccccca attgggatgg agccatcagc ccagtcgtaa
    16561 cgaagtcatc cccaacgtca tgctgaaaca gtccagcatg acggagtggg gaaagcctta
    16621 ccaagccttc accaactccc accttccttc gccgcttctt cctcgcccgg tctgttcgcg
    16681 cgacccagcg tcgcattacg atgcggaaag cggccgaagc gttcaatcat ctcataatgc
    16741 tcccgcgcaa aggccagcga cttctcgtcg cccgctccct cgaacaggct cagcgacagt
    16801 ttctggtcgt cccgcgcttc gctgtgctgg aagggcatgt agaagaacag acgccccgcc
    16861 ccgccgatct ggatgtcata gccatgggca accgcaccgc gcgccacttc cctggcaaga
    16921 ggatcggtcg aaaacgccgc cgccgatccc ctgaacatgt tgcgcggcaa ctggtcgaac
    16981 agcaacaccg ccgccagcgc gtcatcggcc cgctccagaa actcttcggc gggcaaatgg
    17041 cgcttttcct cccataatgc gcggaagcgc gcctgacagg cccggtccag cgccggatca
    17101 tggctccacc acccctgttc cccgatccgg ttgaaccaga aatccagcag ggcagccgcc
    17161 caatcggcgg tcaccgcatc atggctgtcg gtcagcatgt tcatgaaaga gataaagacg
    17221 cactctcacg ctggttcctc cgcccgtggc gttggtgcct caggtcgccg tgccgcccac
    17281 ggtaaggccc tccatcagca gggtcggctg gcccacgccc gccggcacgc tctgcccggc
    17341 cttgccgcac atgccgatgc cttcgtccag cgcccagtca tggccgatgc cgatcacctt
    17401 ggtcagcgcc gtcggcccgt ccccgatcag cgtcgcgccc ttgatcggct cgcccagcct
    17461 gccattctcg accttatagg cctcggtgca ggagaagacg aacttgcccg acacgatgtc
    17521 gacctgcccg ccgccgaagc ttttcgcgaa aatgcccgac ttcatccggc tcagcagctc
    17581 ttccggatcg tcctgtccgc ccttgatgaa ggtgttggtc atgcgcggca tcggcgcatg
    17641 ggcatagctt tcgcggcggc cgttgccggt gggttcgacg cccatcagcc gggcgttcag
    17701 ccgatcctgc atatagccct tgaggatgcc gtcctcgatc agcacatttt ccttcgtcgg
    17761 cgtgccctcg tcatcgatgg agagcgagcc gcgccggctc atgatcgatc cgtcgtcgac
    17821 caccgtgacg cccggcgcgg cgacccgctg gcccacgcgg ccggaaaagg cgctggtgcc
    17881 cttgcggttg aagtcgccct ccaggccgtg cccgatggct tcatgcacca gcacgcccgg
    17941 ccagcccggt cccagcagca cggtcatctc gcccgcgggc gcggccacgg aacgcaggtt
    18001 gacccgcgcc tgcgccagcg cctcgtcaat ggcgcggttc cagatggcgg gttccatcac
    18061 ctcatcgtag agatagcgcc cgccaatgcc gaacacgccc gtctcccggc ggccattctc
    18121 ctccaggatg acggagacgt tgagccgcac cagcgggcgg atgtcggtcg cggtaaagcc
    18181 gtcggcgcgc acgatctcga ccaccgacca gcttcccgcc aggctcaccg acacctgcgc
    18241 gacgcgcgga tcgcgggcgc gggcggcggc gtcgatggcg gcgcagagcg tcaccttctc
    18301 ggcaaagggc acgatctcca gcggattgac gtcggtatag agatggcggt tggtgtgctg
    18361 cggcggcggc gcgggctgcc ccttggccgg atcgagcagc gtcagcgtct cggccgcccg
    18421 gcggatcgcg gcttcgctga tgtcgttggc atgggcgaaa ccggtcatct cgcccgacac
    18481 gccgcgcagg ccgaaacccg catcggtcga ataatcggcg gtcttcagcc gcccatcgtc
    18541 gaagccgaag ctctcgctcg cccgatattg caggtagagt tcgccatcgt cgcagccttt
    18601 cagcgcctcg gcggtcaggc ggcgcgcgcc gtcgggatcg aggaggccgg gccggtagag
    18661 caggccgcgg gcgtcggtga actggggagc agcatcggtc atgccgtccg atataggggc
    18721 ggcagaggct agagccaatc gacattcagc cttgacggcc tgcaaatgac gcttttccgt
    18781 ggttccggtg ctcacctact ttgagtaggc tgcgcgccgg gtcacggaaa accatcattt
    18841 taccttcggt ggtcttcggc tcggctcgtc atcatctgaa tgtcgattgg ccctaagcca
    18901 attaaaaagg catttccatc atccccgcga aggcggggat ccatctcccc cactcgcgtc
    18961 aggcggaacg tgcaggagat ggatttccgc cttcgcggga ataacgattt gaatgggatt
    19021 gccctactta aaggctagcg cccgaaggaa tatccggcag cccggcgatt tccggcgtat
    19081 ccgcaacgct gccggtcagc acgaagcggc ggtcgcaata gccgcagtcg atatagccat
    19141 gctcatcgat ctcaaggaag acgcgcggat ggccgagcgc ggcgggaatg tcgcccgaac
    19201 cgtcgcagga gatgcgggac ttggtgactc ggatgatttc aggcggctgg atcatggccg
    19261 caccgattag cagcgctggc gctgcgccgc aatatccgtg gagacggggc ttacatcagc
    19321 agcaatggcg gcttcttttt cgggcagggc ttctccacgc ccaggtccac cgccttggcc
    19381 ggcgcttccc aatccaggca atcgcgggcg gccgccagcg aaaccggcga aaacatcagc
    19441 aggaaggggg ccaccgttcc agcgagaaga agcgtgagag acatgatgca agtgcctcac
    19501 aaaagcgttc cgttgccgga accttacgcc attcccccgg ccgcgggaac agctttctcc
    19561 aagaaggggg catggtgggc gatgacgggc tcgaaccgcc gacatcctcg gtgtaaacga
    19621 gacgctctac caactgagct aatcgcccga tgcctgtcct gatgccaagc gtccggtgcg
    19681 cgcctatcta cggcaatccg ggcgtcggtc aagcggcgat gcgcaccggt acgtcatgcg
    19741 caaaggaaac ggcggctggc ggtgaaccag cgggtcagcg cctccgccgt gtggtcggcc
    19801 agcgcgatga agacgcggcg cccgtcatgc ggatcggcct gcctgtcgac aaagcccatc
    19861 tcggtcagcg tcctgatcca gcgcagcgcg gtggtgggcg gcacggccga tgcgatgcac
    19921 aggctggaca cggacacgcg ctcatgctcc agccgcgccg ccagcaggtc cagcagcatg
    19981 tcccaggccg ggtcagcgaa cagatcggcg ggcaggaaat cgtcgcgcaa gcgacgcgcc
    20041 cgcaacaggt cgcgcacctg cgccgcttcc agggccgcgg catcggcgga cttgtcggcg
    20101 ctcccgatcg gttccagcgc cggcatgccg atatagtcgc tcggctcgtc cgatatgcgg
    20161 ggccccaggt cgaaggacgg cgtcgcatgg cgcgggcgca gcgtcagcgc ctccagcgtg
    20221 cgggcgaggc ggctcacctc gtcgctcaac tgttgcagcc gcaggccttc attatcccgg
    20281 ttcgcctcgt gcagcgattc ggacggcctc tggcgggcgg ccgccagaag ggcggcggcc
    20341 agatccgtat gccccggccg gcaaagcaat tgcgtccgct cgctgcgcag acaggcatag
    20401 gcaagatcga cggttcccag atcggccact aatatgaccg gcatgtcgtt ctgcagcgcc
    20461 aaggtctcga tctgcaccag cagccgctcg atcatcggat cgggcgtcgg gcagaagcac
    20521 aggatgatgt cgcagccgat ctgcacgtcc agccgggtcg acgcctggtc cagcggcacc
    20581 gtgcccagca gccgaaggcc cgccgcctgg ctcagcatcg cggcgtcgtc cagatagatg
    20641 tcgtcggcca ggatcagcag gcccggccgt tcgtcgcgcg cgccgaaggg ttggtccagg
    20701 gatgcgccga aaccgatctc atcatgatcc aaacccacgc cgaaaatctc catcctgttt
    20761 gttccagctt atcgcaacgc cgtcgttacg cagccaaacc attctccatt atggagataa
    20821 tgccgcccat cgcgttcatg gagcgccctg taaacggctc ttttccagcc tcaccgtaac
    20881 ggaccgccaa aatggagcct cgatccccgc cgaaatggcg ggaatggcgg cattccctta
    20941 gttcatccga aatggatcaa gttttgcgcg ttcttttgct caaaccgcct tttgctcaga
    21001 cagcggtgcg ccgcgcaaag tcgatataga gcgcgcgcag ccgcatcgcg agcgggccgg
    21061 gcttgccgtc cccaatggcc cggccgtcga tccgcaccac cgactggcag agcgtcgaag
    21121 cgctggtgat gaaggcttcc ttcgccgcca acgcttccgc aacggtgaag gggcggcgga
    21181 cgatggcgat gccgctttcc tccgccagcg cggtcagcgc cgcgccggtg cagcccgcca
    21241 gcaccgcctg actatagggc cgggtgacga tgccctcctc cgtcacgatg aaggccgtgg
    21301 acgaagcccc ttcggtgacg aagccgtcct cgaccatcca ggcctcctgc gcgcctgctt
    21361 cggcggcggc gcgcttggcc atggcctggg cgagcaggcc gacgctcttg atgtcgcgcc
    21421 gcgcccagcg caggtcgggc atggtcgcga ccgcgatccc gttgcgcacg gcgggcacgt
    21481 cgaggaaagg cttggcctgg acgaacatga ccagcgtggg ctggatgccg ggcgagggca
    21541 ggaaatcgcg ggtcgcatcg gcgccgcggg tgatctggag atagaccagc ccttcggcca
    21601 gcgcattgcg cgccaccagt tccttctgtg ccgcctcgat ctccgtcagg gagaggggca
    21661 gggcgatgcc gatcgcttgg gtggaccgct ccagccgggc gagatgggac gcgctgtcga
    21721 ccagcttgcc gtcgatcacc gccgcgacct cataaatgcc gtccgcgaac aggaaaccgc
    21781 gatccagcac ggacagctgg gcttgttcca gcggcaggaa gcggccgttc agataggcga
    21841 tggacatggg atgacgatga aatccttgag ggaagagggg gtcgatgttg ccgcttgtgt
    21901 cggccgggtc aagcttatga gcggatttgt accctctccc cttcgtcatg ctgaagcaag
    21961 ttcagcatga cgaaggggag aggggggctc tccgcgtcta aacccgcgct aagccgcctg
    22021 cccgcgcaac gccttctgcc gccgccgctg caccgatgac ccgatcccca tcgcctcgcg
    22081 atatttggcg acggtgcggc gggcgatgtc catgcccttg gcgcgcagca ggtcgaccag
    22141 cgtgtcgtcg gacaagatgg cgtcgggcgt ctcggccgcg atcagcgcct tgatgtggct
    22201 cttgactgcc tcggccgaca ccgcgccgtc gcccccggcc gcagaaacgc cgctggtgaa
    22261 gaaatatttg agttcgtaaa gcccgcgcgg gcaggacaga tatttgttcg acgtcacccg
    22321 gctgacggtc gattcatgca tctggatcgc atccgccacg gccttcagcg tcagcggctt
    22381 cagatgctcc acccccttgc ggaagaaatc ctcctgctgg cggacgatct cgctcgcgac
    22441 cttgatgatg gttttctgcc gctggtcgag cgccttgacc agccagttgg cgctggcgag
    22501 gcagtcggcc agccaggcct tggacgtctt gtcctgcgga ccggacgcca gctcgacata
    22561 ataggtccgg ttgatcagca cgcggggcag ggtggcgctg ttgacctcga tcgcccagcc
    22621 ctcccgcgtc ggccgcacga acaggtcggg cgtcaccggc gccgcgctct cggtggaaaa
    22681 gcgcaggccg ggcttgggat catagtcgcg cagctcgcgg atcatgtccg ccatatcctc
    22741 ctcgtccacg ccgcagatcc ggcgtagctg cggcagcgcc cccttggcga gcaggtccag
    22801 attggcgagc agcttcgcca tgcagggatc gtaacgatcg acctccttgg cctgcaacgc
    22861 cagacattcc gacagcgacc gcgcacccac tccggtcgga tcgaaagcct ggatcaccgc
    22921 cagcacctgt tcgacctgaa agagcggcac ccccatgcca tgggcggtct ccagcagatt
    22981 ggcctccaga tagccggcct cgtcgatctg cccgatcagt tgcgcggcga tcatcaggtc
    23041 catgcccgac agcgcgctgc gggcctgatc catcagatgt tcctgaaggc cctgctccgg
    23101 attggcgaaa ctgtcgaaat ccggcgcctc gccgctgccg ccggacagca ggtccatgcc
    23161 gccggaaccg atggccgccg tcgccatccg gtcgcccggc ccatcgtcga tgaaggtctc
    23221 cgcgctatag tcgacgtcca gcggcgaatc cgcgccgccc agaccctggc cgatcaactg
    23281 gtcggcatcg ccggtctcgg cgcgcaggtc atgctgttcc gccgcccggt ccacgccgtc
    23341 ggcgggcggc gcgaaatcat ccgctccgcc ggattccaat aacgggttct tttccagttc
    23401 gcccgcgacg aacgcctcga tctccagatt ggacagcgcc agcagcttga tcgcctgctg
    23461 aagctgcggc gtcatcacca gcgactggct ctgccgcagg tcgagacggg gcgcgagcgc
    23521 catcagcctt ccccctcgcc gccgtcagga aggacccgcc cgccgcccat gtcagagcga
    23581 gaaattctcg cccagataga gccgacgcac atcggcattg gcgaccagct ccgtcgggct
    23641 gcccgcgaac agcaccttgc cgtcataaat gatgcaggcg cggtccacga tctccagcgt
    23701 ctcgcggaca ttatggtcgg tgatgaggac gccgatgccg cgcgtcttca actgcttcac
    23761 caggtcgcga atatccgcga tggacagcgg atcgatgccc gcgaacggct cgtccagcag
    23821 cacgatcgaa ggattggccg ccaaggcgcg ggcgatctcg caccgccgcc gctcgccgcc
    23881 cgacagcgcc atggcggagg aatcgcgcag ccgggtcagg ccgaattcct ccagcaactg
    23941 ttccagccgc gcctgccgcg ccgccctgtc cggttccgcc agttccagca ccgcgccgat
    24001 attctgcgcc acggtcaggc cccggaagat cgatgtttcc tgcggcagat agcccagccc
    24061 caatatcgac cggcggtaca tgggcaggcc ggtgatgtcc tgcccgtcca gcacgatgcg
    24121 gccatggtcc ggccgcacca gccccatcac cgaatagaag caggtcgtct tgcccgcgcc
    24181 attggggccg agcaggccga ccacctcgcc cttgccgacg gtcagcgaca catcggccag
    24241 cacgacgcgc ttgtcatagc ttttggcgat ggagatgacg gacaggcctt ctcccacttc
    24301 ctgcggggga aggggcgatg ccggggctga gcggtcctgc atcatcacgt cgtccatcac
    24361 gtcatccttg ctgccgcatg cttcttgcgg gttgaatcca tgacccgtgc ggcaattggc
    24421 aagctttgtg catgggatcg ccgccggggc aaggggaaaa tggttccatg cgccttttag
    24481 ggctgtgaaa ggccgcaaga ttgggactgg cggtggcgct ttcaatgacg atggcgggaa
    24541 gcatcctcgg ttggcgag
//
