LOCUS       NZ_CP010954            20792 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Sphingobium sp. YBL2 chromosome, complete genome.
ACCESSION   NZ_CP010954
VERSION     NZ_CP010954.1
KEYWORDS    RefSeq.
SOURCE      Sphingobium sp. YBL2
  ORGANISM  Sphingobium sp. YBL2
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingobium.
REFERENCE   1  (bases 1 to 4766421)
  AUTHORS   Yan,X.
  TITLE     The analysis of one genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4766421)
  AUTHORS   Yan,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2015) College of Life Sciences, Nanjing
            Agriculture University, Weigang Street #1, Nanjing, Jiangsu 210000,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2014
            Assembly Method                   :: Celera Assembler v. 8.0
            Assembly Name                     :: YBL2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina MiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000943805.1-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 04:34:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,219
            CDSs (total)                      :: 5,153
            Genes (coding)                    :: 5,086
            CDSs (with protein)               :: 5,086
            Genes (RNA)                       :: 66
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 25 of 67
            Pseudo Genes (incomplete)         :: 53 of 67
            Pseudo Genes (internal stop)      :: 4 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1862042
            Orig. end                         :: 1882834
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP010954.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from yanxin@njau.edu.cn.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20792
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="5"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20792
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20792
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10792](-)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10792)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     gene            400..1560
                     /locus_tag="TZ53_RS08590"
                     /old_locus_tag="TZ53_08585"
     CDS             400..1560
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019052357.1"
                     /locus_tag="TZ53_RS08590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08585"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_044661040.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.5e-06, bitscore:
                     25.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAYIVEALRTAGGKRKGALSGVHPADLGAVVLNALVDRSGIDP
                     AAVEDVILGCVTQGGEQSFAFGRNVVLASKLPDSVPAVTIDRQCGSSQQALHFAAQAVM
                     SGTQDLVIAAGVESMTRVPMGSNFNLHAQAGIGEGPWPASIRERYGVNEFSQYHGGQAI
                     ADKYGFSREDMDAYALESHRKAAAAIAAGAFEREIVPVDTPDGRFAQDEGVRANGSMEA
                     LAGLKTLTEGGTITAGNASQMTDGASAVLVANEEALKRFDLRPLARIHNLTVTAGDPVI
                     MLEEPIAATERALRRAGLGLDEIDLFEVNEAFASIPMAWLKVLGADPGKLNVHGGAIAL
                     GHPLGASGTKLMATLVHGLRARGKRYGLQAMCEGGGIANVTIVEAL"
     gene            1754..3463
                     /locus_tag="TZ53_RS08595"
                     /old_locus_tag="TZ53_08590"
     CDS             1754..3463
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821240.1"
                     /locus_tag="TZ53_RS08595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08590"
                     /product="ATP-binding protein"
                     /protein_id="WP_025549434.1"
                     /transl_table=11
                     /translation="MDRKLASERGAEQKALAARWTIAAEAMEALAGARSMEAIINVLRA
                     FARRAVGADGIAVVLRDEDQCHYIAEDSMEPLWAGQRFPASSCVSGWAMEHHRTAVIPD
                     VFDDPRVPVEAYRTTFVRSMVMVPIGRIEPMAALGAYWSEFAQPTDNEIALLEALARAA
                     STALENGRLFASLEALNDQLERRVRERTTELERSQDSLRQVQKLDMLGQLTGHVAHDFN
                     NLLMPIVGGLDLILSGKRTPESIERHATIAMQAAESAQTLVQRLLTFARRQPLTAKAVD
                     LSDLLGGMQALLTSTLGPRIALSVDLQPMVPPVRADAHQLEVALLNLAVNGRDAMPDGG
                     ALSIKAQARQSRLPAALTPGPYVCLTVSDTGTGMTPAVKAAAMEPFFTTKPSGHGTGLG
                     LSMVHGLAAQLGGTVEIDSAVGQGTSVRLWLPVERAPAVKAASPAVEEGPKERSGKVLL
                     VDDNDLVRNSTREMLIDMGYEVVDTDRAERALSMIESGDRPDILITDHIMPGMTGVELA
                     LRLRADHPHIALLIISGYEGVDLIAPDITRLSKPFRHNHLQACIAAARAQAA"
     gene            complement(3678..4331)
                     /locus_tag="TZ53_RS08600"
                     /old_locus_tag="TZ53_08595"
     CDS             complement(3678..4331)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019831808.1"
                     /locus_tag="TZ53_RS08600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08595"
                     /product="CoA transferase subunit B"
                     /protein_id="WP_044661041.1"
                     /transl_table=11
                     /translation="MAWTRDEMAARAAKELQDGFYVNLGIGIPTLVANHIPDGVEVTLQ
                     SENGMLGIGPFPYEGEEDADLINAGKQTISELPQSCYFSSADSFAMIRGGHIDLTVLGA
                     MEVSEHGDIANWMIPGKMIKGMGGAMDLVAGVKKIIVVMEHTSKDGSPKFIPACTLPLT
                     GRNVVDMIVTDLCVFQRPDHDSPFRLIECAPGVTAEEVAAKTSAHYTVDVAQPA"
     gene            complement(4331..5041)
                     /locus_tag="TZ53_RS08605"
                     /old_locus_tag="TZ53_08600"
     CDS             complement(4331..5041)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010335662.1"
                     /locus_tag="TZ53_RS08605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08600"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_025549432.1"
                     /transl_table=11
                     /translation="MVKKLYSDAASALEGLLFDGMHLCAGGFGLCGIPERLIDAIRDSG
                     VRDLTIASNNAGVDGEGLGKLLRTRQVRKMISSYVGENKEFERQYLAGELEVEFCPQGT
                     LAERCRAGGAGIPGFYTRTGVGTAVAEGKEVKSFDGQDYILERGIFADVAVIKGWKADE
                     SGNLIFRKTARNFNQPMATAAKICVAEVEEVVPTGSLDPDAIHLPGIYVKRMIVGAPYD
                     KKIEFRTVRQREAA"
     misc_feature    complement(5076..5091)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.45"
                     /tool="antismash"
     misc_feature    5102..5111
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.35"
                     /tool="antismash"
     gene            5126..6028
                     /locus_tag="TZ53_RS08610"
                     /old_locus_tag="TZ53_08605"
     CDS             5126..6028
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004210362.1"
                     /locus_tag="TZ53_RS08610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08605"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_044661042.1"
                     /transl_table=11
                     /translation="MSINRIGLFHLETLLWIDRLGTFAAAAERLNTTQPAISARVRELE
                     SHLGARLFRREGRTMSFTPAGRQLVRDCGPLWSDLQSMLLRCGGLAEASGVVRIGAGEI
                     AAASCLPDFVSQLKGAMPHVSLELEIDLTANLIQQLLVGRADISFAAGPIAHPALQSRP
                     IGGVSLVWLASPAIAASFHGDAADRTIPIWSLASHSPIYGRMRDAIAASQIARKSLNLC
                     NNARMMIDIAKAGGGIGIFPEPMARADLMSGALVKLEGMPALSPIEFHVARRISDNDPV
                     IAAIFEQASALRLGPEGEG"
     gene            complement(6047..6646)
                     /locus_tag="TZ53_RS08615"
                     /old_locus_tag="TZ53_08610"
     CDS             complement(6047..6646)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821239.1"
                     /locus_tag="TZ53_RS08615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08610"
                     /product="hypothetical protein"
                     /protein_id="WP_025549430.1"
                     /transl_table=11
                     /translation="MIRLSLPMRSAIPLLLAASAGPALAQSTILPEGMAIQLETRQEIS
                     SKSARVGDRIELAVAKPVTIGGVTLIPAGSPAVGEVSRVRDNGLLGRSGKLDIKVSTVR
                     AGGMDVPVRGQRNSQGKSGTLGAVGAGIVFLPLAVIVRGKDVKLPAGTLFEVYVDKEVS
                     LGSGVAPGGPAAATPAESRDMPGSIRTVDPNQALGS"
     gene            complement(6938..8719)
                     /locus_tag="TZ53_RS08620"
                     /old_locus_tag="TZ53_08615"
     CDS             complement(6938..8719)
                     /NRPS_PKS="Domain: CAL_domain (148-473). E-value: 7.1e-99.
                     Score: 323.1. Matches aSDomain:
                     nrpspksdomains_TZ53_RS08620_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013849347.1"
                     /locus_tag="TZ53_RS08620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08615"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_044662951.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 4.2e-184, bitscore:
                     612.1, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-81, bitscore:
                     271.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIDFSRSIVDIVLDHGNSVPDRPALIFDQGDGPQSSLTYAQVAA
                     QVGQLAGAMAARGLAAGGPAGPRIALLFSAGTDFALALLACLAVGGVAIPLAPVGRRKA
                     RLRNILNMLDDIRPDCILLDDSMAGLFGEELSAALSAGPVRYLEFAALAAVSHAFSPLA
                     LAPDRLAVLQFTSGTTSNPKGVMISHGNIIANETMIRAAFGHDRDSHFVGWVPHYHDQG
                     LFGNILQPLFLGSTCVITSPAAFINRPMSWLQLISRYRAHTSGGPNFGYDLCVDHATRR
                     GMPDGLDLSGWRVAFNGAERVRPATLDRFAECFAGAGFDRRAFLPCYGLAESTLVTIAV
                     PPRSDPIVKSYDSRALAAGRAEESAGGDAVLDLACCGPAMAGAEARIVDPESGEALPDG
                     AVGEIWLRGPHITAGYIDNPAATEASFGRLDEGGPFLRTGDLGFSTADGFFIVSRLKDL
                     IIVRGRNHAPSDVEQIWSELSGTVGQASAAAVEIEMGDAQHIVLIAEMKRDDGRSLSDE
                     KLQDLAARLRATAMERLELAITDLVMVPASAIPRTTSGKVQRKQAGRMLMDGELTVLGM
                     AGPLAQAFAPPGQRASA"
     aSDomain        complement(7301..8275)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TZ53_RS08620_CAL_domain.1"
                     /evalue="7.10E-99"
                     /label="TZ53_RS08620_CAL_domain.1"
                     /locus_tag="TZ53_RS08620"
                     /protein_end="473"
                     /protein_start="148"
                     /score="323.1"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="FAALAAVSHAFSPLALAPDRLAVLQFTSGTTSNPKGVMISHGNII
                     ANETMIRAAFGHDRDSHFVGWVPHYHDQGLFGNILQPLFLGSTCVITSPAAFINRPMSW
                     LQLISRYRAHTSGGPNFGYDLCVDHATRRGMPDGLDLSGWRVAFNGAERVRPATLDRFA
                     ECFAGAGFDRRAFLPCYGLAESTLVTIAVPPRSDPIVKSYDSRALAAGRAEESAGGDAV
                     LDLACCGPAMAGAEARIVDPESGEALPDGAVGEIWLRGPHITAGYIDNPAATEASFGRL
                     DEGGPFLRTGDLGFSTADGFFIVSRLKDLIIVRGRNHAPSDVEQ"
     CDS_motif       complement(7442..7531)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TZ53_RS08620_0002"
                     /evalue="3.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="TZ53_RS08620"
                     /protein_end="426"
                     /protein_start="396"
                     /score="32.3"
                     /tool="antismash"
                     /translation="PDGAVGEIWLRGPHITAGYIDNPAATEASF"
     CDS_motif       complement(8153..8212)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TZ53_RS08620_0001"
                     /evalue="1.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="TZ53_RS08620"
                     /protein_end="189"
                     /protein_start="169"
                     /score="23.9"
                     /tool="antismash"
                     /translation="AVLQFTSGTTSNPKGVMISH"
     gene            complement(8836..9702)
                     /locus_tag="TZ53_RS08625"
                     /old_locus_tag="TZ53_08620"
     CDS             complement(8836..9702)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054099.1"
                     /locus_tag="TZ53_RS08625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08620"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_044661043.1"
                     /transl_table=11
                     /translation="MIQDEQIEFGGSAAAIRHHYDVGNDFYSAWLDPSMTYSSAMWDGL
                     PKDAPLEEAQQRKLDYHAESVGAGEGMRILDVGCGWGGMMRNLRRRHGAAECVGLTLSE
                     EQLAYIEQSGDPGIGAVLSNWHDYRPDRPFDAIISVGAFEHFAHPQQSVDERRGVYREF
                     FQACRDWMQGKGRLSLQTIAYGRMSPEDANPFIANEIFPAAELPTLEDIVVACKGLFRV
                     ERLRDDGLDYARTCEMWSNRLRGAVRSGVVDPAIHPVEKYSRYLRMSAAGFRMRKIGLL
                     RIAFATE"
     gene            complement(9699..10001)
                     /locus_tag="TZ53_RS08630"
                     /old_locus_tag="TZ53_08625"
     CDS             complement(9699..10001)
                     /NRPS_PKS="Domain: PP-binding (16-81). E-value: 3.4e-13.
                     Score: 41.7. Matches aSDomain:
                     nrpspksdomains_TZ53_RS08630_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821236.1"
                     /locus_tag="TZ53_RS08630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08625"
                     /product="acyl carrier protein"
                     /protein_id="WP_044661044.1"
                     /sec_met_domain="PP-binding (E-value: 5.1e-10, bitscore:
                     37.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSDLIRQASAEEIESWIIARIAEIVNVAPAAVSPDAPFDSFGID
                     SAKAISLMVELENWLNLPDELPLELLFEAEAIRDAATGIAGAVSDMAAQQGGVQP"
     aSDomain        complement(9759..9953)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TZ53_RS08630_PP-binding.1"
                     /evalue="3.40E-13"
                     /label="TZ53_RS08630_PP-binding.1"
                     /locus_tag="TZ53_RS08630"
                     /protein_end="81"
                     /protein_start="16"
                     /score="41.7"
                     /tool="antismash"
                     /translation="WIIARIAEIVNVAPAAVSPDAPFDSFGIDSAKAISLMVELENWLN
                     LPDELPLELLFEAEAIRDAA"
     gene            complement(10001..10792)
                     /locus_tag="TZ53_RS08635"
                     /old_locus_tag="TZ53_08630"
     CDS             complement(10001..10792)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821235.1"
                     /locus_tag="TZ53_RS08635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08630"
                     /product="acyl-homoserine-lactone synthase"
                     /protein_id="WP_044661045.1"
                     /sec_met_domain="Autoind_synth (E-value: 2.2e-24, bitscore:
                     84.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHLISKNNSALYQDEIRDLHQARAEVFVNQLGWDLRVEDGLEYD
                     EYDDARASNIIGFSTENRVVMGLRFRPTDDCSMLLDHFSHVLPAGIRPIDDGRTWELSR
                     GFCIERGMRRHNLRRKAACMIAPLELAYEAGIDRCVGFTDVRMLSFCYGVGWKLTLLGS
                     AMDYGQGEAVAYEVEVSQAALDEMRQMWGLPRPSHITIDQLLPEEENVHVAAARLAREH
                     PELQKIAAQPEIGSVTHPPATTGADVYYGRFGATRSASGGH"
     gene            complement(10912..11460)
                     /locus_tag="TZ53_RS08640"
                     /old_locus_tag="TZ53_08635"
     CDS             complement(10912..11460)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821234.1"
                     /locus_tag="TZ53_RS08640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08635"
                     /product="hypothetical protein"
                     /protein_id="WP_044661046.1"
                     /transl_table=11
                     /translation="MSEYIPSTQLRAGSSTTAADFIAGVDSTLSIESLVTRFSQALGLQ
                     AASHACYDVGDGERRFLFGETGWCGPIAQPEVLPQLCFPITGWDERQYEVEIRLLSMLE
                     SPEERANLHAMATLYLCRGIALLDARDDLAASALTETELFCLDQRQAGWCDLDIAEALD
                     RSVQAVKVHVQRARQKQAA"
     misc_feature    11555..11568
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.24"
                     /tool="antismash"
     misc_feature    complement(11636..11653)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.57"
                     /tool="antismash"
     misc_feature    complement(11676..11685)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.59"
                     /tool="antismash"
     gene            11704..13896
                     /locus_tag="TZ53_RS08645"
                     /old_locus_tag="TZ53_08640"
     CDS             11704..13896
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1107:
                     TonB-dependent receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054096.1"
                     /locus_tag="TZ53_RS08645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08640"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_044661047.1"
                     /transl_table=11
                     /translation="MTNFGYRRRWKWALLVSATIELAASGTARAQAPADADMRADITVT
                     ARKVPEPLLKAPLAVTSISGDSIVAAGLQTITDLTRMAPNVDIGGGIAGQLQGQISIRG
                     ISTLVRNIGLETGVGIYVDDVYVGRPENFVQHLLDVDRVEIVRGPQGTEYGKNTIAGVV
                     NVQTKQPDADPGASIRLDAGNYDYRRGEAVLGTRLNERLSVRGAVAYARQDGFYKHLSG
                     GRDAGSTDLLTWRLSAKYAPTDQLSFIARWEGLRDRGTPAFFQADALAGYPADFPSREP
                     LHINNNRPNRLHRDSQGISLRTEWASDAITLTAITAYRDSSYHASLDDDQEQVDFVSAD
                     NFSDDSHFFSQELRLAGGTGKLRYLLGAYYFDQMVRTDRGLGLGADTGVPGEPMLTTKG
                     SVKTESGALFGRLDYELTDRLSLSAGLRYTREKKRAHFVQDDASGTGIFTYLGFPNLTF
                     DGRSTDDDLSPSATISYEVVPDANVYARFSRGFKSAAYNVDLASSLGGLTASPEKATSY
                     EVGFKMLTLDRRMRLNLAAFHTDYDRLQVSQVLGSGLALTNAGRAQVEGVEGELSLQLT
                     SRLRLEGNAAILDAHYKRFDNCGVPASVIPSVGSPSTDCTGNDLVLAPHFTGYSAVSYE
                     VPVRIGTIFARADVDHRSTVYFEPTNSDAFKAGPRTLVNLRFGLRRGQWDIAAWVQNLT
                     DRIYKTYADDRSGLGVYRTAAYGPPRTYGVSLLAAF"
     misc_feature    11711..11729
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.41"
                     /tool="antismash"
     gene            14068..16185
                     /locus_tag="TZ53_RS08650"
                     /old_locus_tag="TZ53_08645"
     CDS             14068..16185
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686394.1"
                     /locus_tag="TZ53_RS08650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08645"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_044661048.1"
                     /transl_table=11
                     /translation="MDGDQQILASAGVLRWSVDGDGLCHPDAATASRFGVRDGQPLLRW
                     FRGVHRIFRKPVLQLARAVLRMGRAEATLTLEDREGIMRNMRVVARIRRDGAGRPAADL
                     VMIDVTTEHAEIGRLRRSTENLRLIVEYNPQLPWLADPDGRIIDFTDRWLESSGLDREE
                     AEGNGWLAATHPDDIGPLTHRITHSLTTGEPFDVRVRLMVNDQYRWMRAQAYPRRDEEG
                     RIIRWYGYTEDIHESVLIEEQIRWNAEHDSLTQLPNRAMFNACLDKALASAMTDFKKVG
                     VFLLDIDNFKDVNDLMGHHAGDELLKSFASRLKEIFAGDGVVARLGGDEFAILIENVES
                     RQQLADLANRVLTIRETLFAAGRSLECRGSIGVAAFPEDGRVATELLRHADLALYRAKS
                     LGRGRMQMFEQSLLEDMQERVAMINRARTAVRDGTIISYYQPKVSLQTGELVGFEALLR
                     WRDSCGTIRSPAEIYAAFDDHDVADMIGQTMTSQVFADMAAWRARGLTLGHVAINVSSA
                     ELRRERFAGRLIETMDRFSIAPDSIEIEITEGVFLGAGSDTVRRSIDELHMCNIPLALD
                     DFGTGFASLSHLRSLPVSTLKIDRSFVSGVTARESDAAIVSALITLGRALNMKVVAEGV
                     EEADQSVKLRELGCDYAQGFYFGRPAPSENIPALIQSWSENSAIITLNRRAAPWPPRGM
                     RGEGRADSLTA"
     gene            complement(16376..17227)
                     /locus_tag="TZ53_RS08655"
                     /old_locus_tag="TZ53_08650"
     CDS             complement(16376..17227)
                     /EC_number="1.1.1.47"
                     /NRPS_PKS="Domain: PKS_KR (39-201). E-value: 2.4e-11.
                     Score: 35.8. Matches aSDomain:
                     nrpspksdomains_TZ53_RS08655_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821230.1"
                     /locus_tag="TZ53_RS08655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08650"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_044661049.1"
                     /sec_met_domain="adh_short (E-value: 5.3e-34, bitscore:
                     115.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDTEEMIHEDGLPGHESRLEPKPEWEPRYPGSGRLAGKVAIVTG
                     ADSGIGRAVAALYAREGADVAIFYLCEHDDAEKTAGIVRAEGRRALTIAGDLGDRDFCQ
                     RAVAQVVEQFGRIDILVNNAGEQHPDSDITDISEEQLRRTFQTNIFAMFFLTQAVRPHL
                     KRGAAIVNCTSVTMYQGSKELLDYSSTKGAITAFTRSLSENLVGDGIRVNAVAPGPIWT
                     PLNPSGGASPEKLEHFGESTPMGRPGQPNEVAPSFLFLACDDASYMSGQVLHPNGGTIV
                     NG"
     aSDomain        complement(16625..17110)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TZ53_RS08655_PKS_KR.1"
                     /evalue="2.40E-11"
                     /label="TZ53_RS08655_PKS_KR.1"
                     /locus_tag="TZ53_RS08655"
                     /protein_end="201"
                     /protein_start="39"
                     /score="35.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIVTGADSGIGRAVAALYAREGADVAIFYLCEHDDAEKTAGIVR
                     AEGRRALTIAGDLGDRDFCQRAVAQVVEQFGRIDILVNNAGEQHPDSDITDISEEQLRR
                     TFQTNIFAMFFLTQAVRPHLKRGAAIVNCTSVTMYQGSKELLDYSSTKGAITAFTRSL"
     gene            17324..17932
                     /locus_tag="TZ53_RS08660"
                     /old_locus_tag="TZ53_08655"
     CDS             17324..17932
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004209542.1"
                     /locus_tag="TZ53_RS08660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08655"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_044661050.1"
                     /transl_table=11
                     /translation="MVLKALALNCTLKAGEGESSSTDAMIAVLAKALAAHDVELTGTVR
                     VAALDIRPGVTSDEGEGDAWPALRRRILDHDIVIFGGPIWLGQISSVAKRVLERMDAFL
                     GETDDRGRMPSYGKVAVAAIVGNEDGAHFSTAQWFQALNDVGWTVPATAACYWVGEAMG
                     SIDFKDLGQVPEKVEKTAKMVAGNAAHLAGLLRSSPYPG"
     gene            17939..18895
                     /locus_tag="TZ53_RS08665"
                     /old_locus_tag="TZ53_08660"
     CDS             17939..18895
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008830328.1"
                     /locus_tag="TZ53_RS08665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08660"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_044661051.1"
                     /transl_table=11
                     /translation="MAKTGRVAHIRKNIVLYGALLANIGIAVAKFVASALTGSSSMLTE
                     GVHSMVDSGNQLLLLYGQARAKKPADAAHPFGYGRELYFWAFVVAILIFAVGAGVSIYE
                     GWLHIRQPEPLRDPAVNYIVLAIAFLMEGASWTIAVREFGRKRGPSSWWQSIRRSKDPA
                     GFIVLFEDSAALIGLIVAAIGVWASHYFGNARLDGVASIVIGLGLGAVAVLLAREAKGL
                     LIGESADRAIIDAVWALLDRRPEITAVNHIRTIHTAPDAVFVAISADFADDLRMGRAES
                     LIEEMESEMKRAIPELTSIYIRPEKREDALVQPRASA"
     misc_feature    complement(17963..17977)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.72"
                     /tool="antismash"
     misc_feature    complement(17971..17986)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.33"
                     /tool="antismash"
     misc_feature    18934..18948
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.83"
                     /tool="antismash"
     gene            19016..20305
                     /locus_tag="TZ53_RS08670"
                     /old_locus_tag="TZ53_08665"
     CDS             19016..20305
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686399.1"
                     /locus_tag="TZ53_RS08670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_08665"
                     /product="MFS transporter"
                     /protein_id="WP_044661052.1"
                     /transl_table=11
                     /translation="MLSATLARQMGTRQIHYGWAVLAATFFTMLVVAGAVGAPGVFIIP
                     LQKEYGWSSADISGALAIRFLLFGGMGPFAAAFMNRFGVRRMMLISLSIIVGGLLLSMG
                     MTRLWHLVLLWGVVIGVGTGLTAMVLGATVATRWFAHRRGLVMGLLSASTATGQLAFLP
                     LLAALTERFGWRASILLVCGAILLAAMVVLLLMRDRPADLGLPPYGESEVHPAPPQPAS
                     FGALLMSPLRILADAARVPSFWILFFSFYICGASTNGLVQTHFIALCGDYGLAAVGAAS
                     MLAMMGLFDFAGTLASGWLSDRFDNRWLLFWYYGLRGLSLLYLPFSDFSLYSLSVFAMF
                     YGLDWVATVPPTVKLTAQRFGPERANVVFGWIFAGHQLGAASAALAGGLSRTVWQSYMP
                     AFVAAGILCLIGAGLVLLINRARSKTFVLA"
     misc_feature    complement(20560..20575)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.1"
                     /tool="antismash"
ORIGIN
        1 ccgcctatag cgcctccaag ggcggcgtcg tcggcatgac cctgcccatc gcccgcgacc
       61 tggcgcagca caagatccgt gtgatgacca tcgcgccggg tatcttcctg acgcccatgc
      121 tggaggcgtt cccccagcat gtgcaggatg cgctgggcgc gcaggtgccg catcccagcc
      181 gccttgggaa gcccgacgaa tatgcgcagc tcgtggacag catcatcgcc aatcccatgc
      241 tgaacggcga ggtcatccga ctggacggcg cgatccgaat ggcgccgcgt tgagcggccc
      301 cggcaggcga agcgctggtt ccacgcgcgc ccctgccgcc ttctggagcg gggaaccggt
      361 ttggtccgcc gctcctcctc atgtcgaagg aagctgaaaa tggccgaagc ctatattgtc
      421 gaggcgctgc gtactgccgg cggcaagcgc aagggcgcgc tgtcgggcgt tcatccggcg
      481 gatctgggcg ccgtggtgct gaacgcattg gtcgaccgca gcggcatcga tcccgccgcg
      541 gtcgaggatg tcatattggg ctgcgtcacg cagggcggcg aacaatcctt cgccttcggc
      601 cgcaatgtcg tgctggcgtc gaagctgccc gacagcgttc ccgccgtcac catcgaccgg
      661 cagtgcggat cgtcgcagca ggcgctgcat ttcgcggcgc aggcggtgat gtccggcacg
      721 caggatctgg tgatcgcggc cggcgtggaa agcatgacgc gcgtgccgat gggctccaac
      781 ttcaatctgc atgcgcaggc gggaattggg gaagggccat ggcccgccag catccgcgag
      841 cgctacggcg tcaacgagtt cagccagtac catggcgggc aggcgattgc cgacaaatat
      901 ggcttcagcc gcgaagacat ggacgcctac gcgctggaga gccatcgcaa ggccgcggcc
      961 gccatcgccg cgggcgcttt cgagcgcgag atcgtgccgg tcgacacgcc ggacggccgc
     1021 ttcgcgcagg atgagggcgt gcgcgccaat ggatcgatgg aggcgctggc cgggctcaag
     1081 acgctgaccg aaggcggcac gatcaccgcc ggcaatgcga gccagatgac cgatggcgcc
     1141 tccgccgtgc tggtcgcgaa tgaggaggcg ctgaagcggt tcgacctgag gccgctggcg
     1201 cgcatccata atctgacggt gacggcgggc gaccccgtca tcatgctgga ggaaccgatt
     1261 gcggccacgg aaagggcgct gcgccgggcg gggctgggcc tggacgagat cgacctgttc
     1321 gaagtgaacg aagctttcgc ttccattccc atggcctggc tgaaggtgct gggcgctgat
     1381 ccgggcaagc tgaacgtcca tggcggtgcg atcgcgctgg gccaccctct cggcgcgagc
     1441 gggacgaagc tgatggcgac ccttgtccat ggattgaggg cgcggggcaa gcgctatggg
     1501 ctgcaagcca tgtgcgaagg cggcggcatc gccaatgtga ccatcgtcga ggcattgtga
     1561 cggttcctgc ggagcgggcg tcgcgggctt gcgcgcccgg cgcccgcgcc ggcggaccgg
     1621 cggatgaaca gggttaagga tgagttgacg ggccgcaaac ccaggccgcc tctaagccat
     1681 tgatcataat cgctttgtga tcgacgccgt ccgatgttag aaagacgcgc ggttccgatg
     1741 cagaaggttg tcgatggaca ggaaattggc aagcgaacgg ggtgccgaac aaaaggcgct
     1801 ggcggcacga tggaccatag ccgccgaagc catggaggcg ctggccggcg cgcggtcgat
     1861 ggaagcgatc ataaatgtcc tgcgggcctt cgcgcgccgc gcggtggggg cggacggcat
     1921 cgcggtcgtc ctgcgcgacg aggaccagtg tcattatatc gctgaagatt cgatggaacc
     1981 gctctgggcg ggacagcgct tcccggcatc gagttgcgtg tccggatggg cgatggagca
     2041 tcatcggacg gcggtgatcc cggacgtctt cgacgatccc cgcgtgccgg tggaggccta
     2101 tcgcaccaca ttcgtgcggt cgatggtgat ggtgccgatc ggccgcatcg aacccatggc
     2161 cgctctgggc gcctactggt ccgaattcgc gcagcccacc gacaatgaga tcgctctgct
     2221 ggaggcgctg gcccgcgccg cgtccaccgc gctggagaac gggcggctgt ttgcgtcgct
     2281 ggaagcgctg aacgaccagc tcgaacgccg cgtccgggaa cgcaccacgg aactggagcg
     2341 gtcgcaggac agcctgcgcc aggtccagaa gctggacatg ctcggccagt tgacgggcca
     2401 tgtcgcccat gacttcaaca atctgctgat gccgatcgtc ggcgggctgg acctgatcct
     2461 gtcgggcaag cggacgcccg aatcgatcga gcggcatgcg accatcgcga tgcaggcggc
     2521 ggagagcgcg cagacgctgg tgcagcggct cttgaccttt gcccgccgcc agcccctgac
     2581 cgcaaaggcg gtcgacctgt cggacctgct tggcgggatg caggccttgc tgaccagcac
     2641 gctgggaccg cggatcgcgc tgtccgtcga tctccagccg atggtgccgc cggtgcgcgc
     2701 ggacgcccat cagcttgagg tcgcgctgct caacctggcc gtcaacggcc gcgacgccat
     2761 gcccgacggc ggcgcgctca gcataaaggc gcaggcgcgc caaagccgcc tgcccgccgc
     2821 gctgacgccc ggtccctatg tctgcctgac cgtcagcgac accggcaccg gcatgacccc
     2881 ggcggtcaag gcggcggcca tggagccctt cttcacgacc aagccgtccg gccatggcac
     2941 ggggcttggc ctttccatgg tccatggcct tgccgcccag cttggcggca cggtggagat
     3001 cgacagcgcc gtggggcagg gcaccagcgt ccggctatgg ctgcccgtcg agcgggcgcc
     3061 tgccgtgaag gcggcttccc cagcagtcga ggagggaccg aaagagcgtt cgggcaaggt
     3121 gctgctggtg gacgacaacg atctcgtccg gaatagcacg cgggagatgc tgatcgacat
     3181 gggctatgag gtggtcgaca ccgaccgggc cgaacgcgcg ctcagcatga tcgaatccgg
     3241 cgaccggccg gacatcctga tcaccgacca tatcatgccg ggcatgacgg gggtggaact
     3301 ggcgctgcgc ctgcgggccg atcatccgca catcgcgttg ctgatcatat cgggctatga
     3361 gggggttgac ctgatcgcgc ccgacatcac gcgcctgtcc aagcccttcc ggcataatca
     3421 cttgcaggcc tgcatagccg cggcgcgggc gcaggcagcc tgatccgcat cctgtttcgg
     3481 ggtcacggcc cctctgcgga gaaaagcttg gcgccggcct ggcccggata tgtcctgtgg
     3541 cgcttcgctt cactctattc aggctatccc tgaacaggat gactttgccg tggatcggac
     3601 gacgcgaccc agggcgcatt cgctttcatg cctgaggcgg cgaggcccat tgacgggagg
     3661 ggcctcgccc tctttcctca ggccggttga gcgacgtcca ccgtgtaatg cgcactggtc
     3721 ttggcggcga cttcctccgc cgtcacgccc ggcgcgcatt cgatgaggcg gaacgggctg
     3781 tcatggtcgg gccgctggaa cacgcagagg tcggtgacga tcatgtcgac cacattcctg
     3841 cccgtcagcg gcagggtgca ggccgggatg aacttgggac tgccgtcctt ggacgtgtgt
     3901 tccatgacga cgatgatctt cttgacgccc gcgaccagat ccatcgcgcc gcccatgccc
     3961 ttgatcatct tgcccgggat catccagttg gcgatgtcgc catgttccga aacctccatc
     4021 gcgcccagca cggtcaggtc gatatgcccg ccccggatca tcgcgaagct gtcggcgctg
     4081 gaaaaatagc agctctgcgg caattcgctg atcgtctgct tgcccgcatt gatcaggtcg
     4141 gcatcctcct ccccctcata ggggaaaggg ccgatgccca gcatgccatt ctccgactgc
     4201 agcgtcactt ccacgccgtc gggaatgtgg ttcgccacca gcgtcgggat gccgatgccc
     4261 agattcacgt agaaaccgtc ctgcaattcc ttcgccgccc gcgcggccat ttcgtcacga
     4321 gtccatgcca ttatgcggcc tccctctggc ggacggtgcg gaattcgatt ttcttgtcgt
     4381 aaggcgctcc gacgatcatg cgcttgacgt agatgccggg cagatggatc gcatcggggt
     4441 cgaggctgcc ggtgggcacc acctcctcca cttccgcgac gcagatcttc gccgccgtcg
     4501 ccatgggctg gttgaagttg cgcgccgtct tgcggaagat gaggttgccg ctctcatcgg
     4561 ccttccagcc cttgatgacc gccacatcgg cgaagatgcc gcgctccaat atataatcct
     4621 gcccgtcgaa gctcttcact tccttgccct cggccaccgc cgtgccgacg cccgtcctgg
     4681 tgtagaagcc cggaatgccc gcgccgcccg cccggcagcg ttcggccagc gtgccctgcg
     4741 ggcagaactc cacctccagc tccccggcca gatattgccg ctcgaactcc ttgttctcgc
     4801 ccacatagct ggagatcatc ttcctgacct gccgcgtgcg cagcagcttg cccagcccct
     4861 cgccatctac ccccgcattg ttggaggcga tggtcagatc cctgacgccc gaatcccgga
     4921 tcgcatcgat cagccgctcg ggtatcccgc acagaccgaa cccgccagcg cacagatgca
     4981 tgccgtcgaa cagcaaacct tccaacgcac tcgccgcatc cgaataaagc tttttgacca
     5041 taagcatgcc tctccttcgg atcgccattc tggcggaggc caattatcat ttctaatgat
     5101 ttgttttttg ctttagccaa aagccatgtc tatcaatcgc atcggcctct tccatctgga
     5161 aaccctgctc tggatcgacc ggctcggcac gttcgctgcg gcggcggagc ggttgaacac
     5221 cacccagccg gcaatttcgg cgcgggtaag ggaactggag agccatctgg gcgcccgcct
     5281 gttccgccgc gaaggccgga ccatgtcctt cacccccgcc gggcggcaac tggtgcgcga
     5341 ttgcgggcct ctctggagcg atctgcagag catgctgctg cgctgcggcg gattggcgga
     5401 agcgagcggc gtggtccgca tcggcgcagg cgaaatcgcc gcggcaagct gccttccgga
     5461 cttcgtgtcg caattgaagg gggcaatgcc gcatgtcagc ctggaactgg aaatcgacct
     5521 gaccgccaac ctgatccagc aattgctggt cgggcgcgcc gatatttcct tcgcggccgg
     5581 gcccatcgcg catccggcgc tccagtcgcg tcccatcggc ggggtgagcc tggtctggct
     5641 cgccagtccc gccattgccg cgtcattcca cggcgatgcg gcggaccgca ccattccgat
     5701 ctggtcgctg gccagccatt ccccgatcta tgggcggatg cgcgacgcga tcgccgcttc
     5761 gcagatcgcc cgtaaatcgc tcaacctgtg caacaatgcg cggatgatga tcgacatcgc
     5821 caaggcgggt ggcgggatcg gcatcttccc ggaacccatg gcccgcgccg acctgatgag
     5881 cggagccctc gtgaaactgg agggcatgcc ggccctgtcg cccatcgagt tccatgtggc
     5941 caggcgtatt tcggacaatg atccggtgat cgccgccatt ttcgagcagg cgagcgcact
     6001 gcggctgggg ccggagggcg agggctgacc gctgtcgaga cgggcttcag gaacccagcg
     6061 cctgattggg atcgactgtc cttatgctgc cgggcatatc gcggctttcg gccggagtgg
     6121 cggcggccgg gccgcccggc gccacgcccg atcccaggga aacctccttg tcgacataga
     6181 cctcgaacag cgtgccggcg ggcagcttga cgtcctttcc gcggacgatc accgccagcg
     6241 gcaggaagac gatgcccgcg cccaccgcgc ccagggtgcc ggacttgccc tgggaattgc
     6301 gctggccgcg caccggcacg tccatcccgc ccgccctgac cgtgctgacc ttgatgtcga
     6361 gcttgcccga gcggccgagc aggccattgt ccctgacgcg gctcacttcc cccaccgccg
     6421 ggctgccggc ggggatgagc gtcacgccgc cgatcgtcac gggcttggcc acggccaatt
     6481 cgatcctgtc gccgacgcgg gcggatttgg aggaaatctc ctgccgggtt tccagttgga
     6541 tggccatgcc ttcgggaagg atcgtcgatt gggcaagggc gggaccggcg ctcgccgcca
     6601 gcagcagggg gatggcagag cgcatcggca atgacaggcg aatcatcggt ccatcctctc
     6661 cgcttcggcg gccacgcccc cgaccgccgt gcaatttacg cttccggggc cagggcatca
     6721 aggaacgagt cgggcctggc gcgggcgaac ggcgcagcca ttgccgcgac gaccttccgc
     6781 tgtgccgacc gtcagccaga gcgccgcatt caatcgggcg caggtcgcgc cttcgcgcgg
     6841 atgccgatgc gggagacggc cgggcggacg ccggccgatc ccggccctca gagcttcgcc
     6901 ttcgggccga accgcgttca gccctgtcag gacgaactca ggccgatgcc ctttgcccgg
     6961 ggggcgcgaa cgcctgcgcc agcggtcccg ccatgcccag caccgtcaat tccccgtcca
     7021 tcagcatcct gccggcctgc ttgcgctgca ccttgccgct ggtcgtgcgg gggatcgcgc
     7081 tggcgggcac catcaccaga tcggtgatgg ccagttccag ccgctccatg gccgtggcgc
     7141 gcagccgggc ggcaaggtcc tggagtttct cgtccgacag ggaccggccg tcgtcgcgct
     7201 tcatctccgc gatcaggacg atatgctgcg catcgcccat ctcgatctcc acggcggcgg
     7261 cgcttgcctg tcccaccgtg ccggaaagtt ccgaccagat ctgttcgaca tcgctgggcg
     7321 catggttgcg gccccggacg atgatcaggt ccttgaggcg gctgacgatg aaaaatccat
     7381 cggccgtgga aaagccgaga tcgccggtgc gcaggaacgg cccgccttcg tccagccggc
     7441 cgaagctcgc ctccgtcgcg gcgggattgt cgatatagcc ggcggtgatg tgcgggccgc
     7501 gcagccagat ttcgcccacc gcgccatcgg gcagcgcctc gccgctttcg ggatcgacga
     7561 tccgcgcctc cgccccggcc atggcggggc cgcagcaggc gaggtccagc acggcgtccc
     7621 cgccggcgct ctcctccgcc cgacctgccg cgagagcgcg gctgtcgtag ctcttgacga
     7681 tggggtcgct ccggggcgga accgcgatgg tcacgagggt ggattcagcc agtccatagc
     7741 aaggcaggaa ggcgcgcctg tcgaaaccgg caccggcaaa gcattcggca aagcggtcga
     7801 gcgtggcagg ccgcacccgc tccgccccgt tgaacgcgac gcgccagccc gacaggtcga
     7861 gaccgtccgg catgccccgc cgcgtggcat ggtcgacgca aaggtcgtag ccgaaattgg
     7921 gcccgccgct ggtatgcgcg cgatagcggg aaatgagttg cagccaggac atcggcctgt
     7981 tgatgaacgc ggcgggcgag gtgatcacgc aggtcgagcc caggaacagc ggttgcagga
     8041 tattcccgaa cagcccctga tcgtgataat gcggcaccca gccgacgaaa tgggaatccc
     8101 ggtcgtggcc gaaggcagcg cggatcatcg tctcattggc gatgatgttg ccatggctga
     8161 tcatcacccc cttcgggttc gacgtggtgc cggaggtgaa ctggagcacg gcgagccggt
     8221 ccggcgcgag cgccagcggc gagaaggcgt gcgataccgc cgcgagcgcg gcaaattcca
     8281 gatagcgcac cgggccggcg gacagggcgg cggacagttc ctccccgaac aggccggcca
     8341 tgctgtcgtc cagcaggatg cagtcgggcc ggatgtcgtc cagcatgttc aggatattcc
     8401 gaagccgcgc cttgcgccgg ccgaccgggg cgagcggaat ggcgacgccg ccgaccgcga
     8461 ggcaggcaag cagcgcgagc gcgaagtcgg ttcccgccga gaagaggagg gcgatccggg
     8521 gaccggccgg cccccccgcc gccaaccccc gtgccgccat ggcgccggca agctgcccga
     8581 cctgcgccgc cacctgcgca taggtcaggc tgctctgcgg accgtcgccc tggtcgaata
     8641 tcagcgccgg ccggtccggg acgctgttcc catggtccag tacgatgtcg acgatcgacc
     8701 ggctgaagtc tatctgcatc ttttttgcga acccgatgct ttggagcctt ttcacatgga
     8761 gcgaaaacgc ccagtccttt gatgccgcat gatcccggtc gccaggcgat tccgcccggc
     8821 ttggggatgt tctggtcatt ccgtcgcgaa ggctatccgg agcaggccga tcttccgcat
     8881 gcggaaaccg gcggccgaca tgcgcagata acgggaatat ttctcgaccg gatggatggc
     8941 cggatcgacc accccgctgc ggaccgcgcc gcgcagccgg ttgctccaca tctcgcaggt
     9001 gcgcgcatag tctagcccgt cgtcgcgcag ccgctcgacg cggaacagac ccttgcaggc
     9061 gaccacgatg tcctccagcg tcggcagttc cgccgccggg aagatctcgt tcgcaatgaa
     9121 gggattggcg tcctccggcg acatcctgcc ataggcgatg gtctggagcg acagacggcc
     9181 cttcccttgc atccagtcgc ggcaggcctg gaagaattcg cggtacacgc cgcggcgctc
     9241 gtccacgctc tgctgcggat gggcgaaatg ctcgaacgcg ccgacggaga tgatcgcgtc
     9301 gaacggcctg tcgggacgat agtcgtgcca gttggaaagg accgcgccga tgccgggatc
     9361 gcccgattgc tcgatatagg cgagctgttc ctcgctcagc gtcaggccga cgcattcggc
     9421 ggcgccatgc ctgcgccgca ggttgcgcat catgccgccc cagccgcaac cgacgtccaa
     9481 tatgcgcatg ccctcgccgg cgccgaccga ttccgcatga tagtcgagct tgcgctgctg
     9541 cgcctcctcc agcggggcgt ccttgggcag gccgtcccac atcgcgctgg aataggtcat
     9601 gctggggtcg agccacgccg aatagaagtc gttgccgaca tcataatggt ggcggatggc
     9661 ggcggccgat ccgccaaatt cgatctgttc gtcctggatc atggctggac gccgccctgc
     9721 tgggccgcca tgtcgctgac cgccccggcg atgcccgtcg ccgcgtcgcg gatcgcctcc
     9781 gcctcgaaca acagttccag cggcagttcg tcgggcaggt tcagccagtt ctccagctcc
     9841 accatcaacg agatcgcctt ggcggaatcg atcccgaaac tgtcgaacgg cgcatcggga
     9901 gagacggcgg cgggcgccac attcacgatt tcagcgatgc gggcaatgat ccagctttcg
     9961 atttcctctg ccgatgcctg tcgaataagg tcggaattca tcaatgtccc cctgaagccg
    10021 aacgggtcgc cccgaatctg ccataataga cgtccgcccc ggtcgtggcg ggcgggtgtg
    10081 tgacggaacc gatctccggc tgggcggcga tcttctgcag ttctggatgc tcgcgcgcca
    10141 gccgggccgc cgcgacgtgc acattctcct cctccggaag aagctggtcg atggtgatgt
    10201 gcgaaggccg gggcaggccc cacatctggc gcatctcgtc gagcgcggcc tgcgacacct
    10261 ccacctcata ggcgacggcc tccccctggc catagtccat ggcggaaccg agcagggtca
    10321 gcttccagcc gacgccgtag cagaagctga gcatgcggac atcggtgaag cccacgcaac
    10381 ggtcgatccc ggcctcatag gccagttcca gcggcgcgat catgcacgcg gccttccgtc
    10441 gcagattgtg gcggcgcatg ccccgctcaa tgcagaatcc gcggctcagt tcccaggtgc
    10501 gcccgtcgtc gatggggcgg atgccggcgg gcaggacatg cgaaaaatga tcgagcagca
    10561 tggaacagtc gtcggtgggg cggaaacgca gccccatgac gacccggttc tcggtcgaaa
    10621 agcctatgat gttgctcgcg cgcgcatcat catattcgtc atattccaat ccgtcctcga
    10681 ccctgagatc ccagccgagc tggttgacga acacctccgc gcgggcctgg tgcaaatctc
    10741 tgatctcgtc ctggtacagt gcggaattgt tcttcgaaat cagatgaatc aaatccgttc
    10801 gtcccccgca tgcagcggca gcgcctgtaa catattatac aggggaggtc atcggaaagt
    10861 tgcagggtgc aatccatgtt ccccgcaaaa aacccggtcg ataaaggggg ttcaggcggc
    10921 ctgcttctgc cgggcgcgct ggacatgcac cttcaccgcc tggacggagc ggtcgagcgc
    10981 ctcggcaatg tcgaggtcgc accacccggc ctgccgctgg tcgaggcaga acagctcggt
    11041 ctcggtcagg gcggaagcgg ccagatcgtc gcgcgcgtcg agcagggcga tgccccggca
    11101 caggtagagc gtcgccatgg cgtgcaggtt cgcgcgttcc tccgggcttt ccagcatgct
    11161 cagcaggcgg atctccacct catattgccg ttcgtcccag ccggtgatcg gaaagcagag
    11221 ctgcggcagg acctccggct gtgcgatcgg cccgcaccag ccggtctcac cgaacaggaa
    11281 gcgccgctcc ccatcgccga catcgtagca ggcatggctc gccgcctgaa ggcccagggc
    11341 ctggctgaag cgggtgacga ggctctcgat gctgagcgtg ctgtcgaccc ccgcgatgaa
    11401 atcagcggcg gtggtcgaac ttccggcgcg aagctgggtg ctggggatat attcgctcat
    11461 ggttcctcac gcggcatatg cctgccgtca tgccgcgtca ggtcttaaaa gcgggttaag
    11521 cgtgccttcc tgccgcctgc ttcctgtttg cggcggaacg agcgttcgcc ggggtgcggg
    11581 gccgccggcc gcagaccgca agctcgtccg atccggagcc ggacgcagga agagtttaac
    11641 cagcggttta ccaagtccgc ctatgatcgg cggattgaaa aaatatagcg ggtttcgtgg
    11701 gcgatgacga attttggata caggcggcga tggaagtggg cacttctggt ttccgcgacg
    11761 atcgaactgg cagcttccgg cacggcccgg gcgcaggccc cggccgatgc ggacatgcgc
    11821 gccgacatca cggtgacggc gcgcaaggtg ccggaaccgc tgctgaaggc gccgctggcg
    11881 gtcaccagca tttcaggcga ttcaatcgtg gcggcggggt tgcagaccat caccgacctg
    11941 acccgcatgg cccccaatgt cgacatcggc gggggcattg caggccagtt gcaggggcag
    12001 atctcgatcc gcggcatctc caccctggtc cgcaatatcg ggctggaaac cggcgtcggc
    12061 atctatgtgg acgatgtcta tgtcggccgg ccggaaaatt tcgtccagca tcttctggat
    12121 gtcgaccggg tggaaatcgt gcgcggcccg caagggacgg aatatggcaa gaacaccatc
    12181 gccggcgtcg tcaacgtcca gacgaagcag cccgacgccg atcccggcgc ctccatccgg
    12241 ctggacgcgg gcaattacga ttacaggcgg ggcgaggcag tgctgggcac gcgcctcaac
    12301 gaacggcttt cggtgcgcgg cgcggtcgcc tatgcccggc aggacggctt ctacaagcat
    12361 ctgtccggcg gcagggatgc gggatcgacc gacctgctga cctggcggct gtcggccaaa
    12421 tatgcgccga ccgaccaact gtccttcatc gcccggtggg aggggctgcg cgaccgcggc
    12481 acgcccgcct tcttccaggc ggacgcgctg gccggctatc cggcggattt cccttcgcgg
    12541 gagccgctgc acatcaacaa caaccggccc aaccggctgc accgcgacag ccagggcatt
    12601 tcgctgagga cggaatgggc atcggacgcg atcacgctga cggccatcac cgcctatcgc
    12661 gattcctcct atcatgcctc gctggacgac gatcaggagc aggtcgactt cgtctccgcg
    12721 gacaatttca gcgacgattc ccatttcttc agccaagaac tgcggctggc gggcggcacc
    12781 ggcaagctgc gctatctgct gggcgcctat tatttcgacc agatggtgcg caccgaccgg
    12841 ggcctgggtc tgggcgccga taccggcgtg ccgggcgaac cgatgctgac caccaagggc
    12901 agcgtcaaga cggagagcgg ggcgctgttc gggcggctcg actatgaact gaccgatcgc
    12961 ctgtcgcttt ccgccggcct gcgctacacc agggagaaga agcgcgccca tttcgtccag
    13021 gatgacgcca gcgggacggg tatcttcacc tatctgggct tcccgaacct caccttcgac
    13081 ggccggtcga ccgatgacga cctgtcgccc agcgcgacca tttcctatga ggtcgtgccg
    13141 gacgccaatg tctatgcgcg cttctcccgc ggcttcaaga gcgcggctta caatgtcgac
    13201 ctcgcctctt cgctgggcgg gctgaccgcc agcccggaaa aggcgaccag ctatgaggtc
    13261 ggcttcaaga tgctgacgct ggaccggcgg atgcggctga accttgccgc gttccacacc
    13321 gattacgacc ggttgcaggt gtcgcaggtg ctgggcagcg ggctggcgct caccaatgcc
    13381 ggccgcgcgc aggtggaggg cgtggaaggc gagctgtcgc tgcagctgac gtcccggctg
    13441 cggctggagg ggaatgccgc cattctggac gcacattata agaggttcga caattgcggc
    13501 gttcccgcat cggtcattcc ctctgtcggc agccccagca ccgactgcac cggcaacgac
    13561 ctggtcctgg cgccccattt caccggctat agcgccgtca gctatgaggt tccggtgcgg
    13621 atcggcacga tcttcgcccg cgcggacgtg gatcaccggt cgaccgtcta tttcgagccg
    13681 accaattcgg acgccttcaa ggccgggccg cgcacgctgg tcaacctgcg tttcggcctg
    13741 cgtcgcgggc agtgggacat cgccgcctgg gtccagaacc tgaccgacag gatctacaag
    13801 acctatgccg acgaccggtc cggtctgggc gtgtaccgaa cggcggcata cgggccgccg
    13861 cgcacctatg gcgtcagcct tttggcggca ttttaggacg tcgcgcttgg gcgtgctggc
    13921 tatggcccag atggcggcca ttaaggaaat cttagccagc aaatggtgaa accttcttaa
    13981 gggccgcggc gccgggacag caggagtaga atggcggacc agatttcatc gcggtcacct
    14041 gatgaatttc aaggcaggca ggacccgatg gatggcgacc agcagatact ggcgtcggca
    14101 ggggtcttgc ggtggtcggt tgacggggat gggctatgcc atcccgatgc cgccaccgcg
    14161 agccgtttcg gcgtgcggga cggccagccg ctgcttcgct ggttccgcgg cgtgcaccgg
    14221 atctttcgca agcccgtcct ccagcttgcc cgtgccgttc tgcgcatggg cagggccgaa
    14281 gcgacgctga cgctggagga tcgtgaaggc atcatgagga atatgcgtgt cgtcgcgcgc
    14341 atccgtcgtg acggggcggg ccggcccgcg gccgacctgg tgatgatcga cgtcacgacc
    14401 gaacatgccg aaatcggacg gctgcgccgc agcacggaaa atctgcgcct gatcgtcgaa
    14461 tataatcctc agcttccctg gctggccgat cccgacggcc ggatcatcga cttcaccgat
    14521 cgctggctgg aaagttccgg cctggaccgg gaggaggcgg agggcaatgg ctggctggcg
    14581 gcgacgcatc cggatgacat cggcccgctg acccaccgga tcacccattc gctgaccacc
    14641 ggcgagccct tcgacgtgcg cgtccggctg atggtcaacg accagtatcg ctggatgcgg
    14701 gcgcaggcct atccccggcg cgacgaggaa ggccggatca tccgctggta cggctatacc
    14761 gaggacatcc atgaaagcgt gctgatcgag gagcagatac gctggaacgc cgagcatgat
    14821 tcgctgacgc agctgcccaa ccgggcgatg ttcaacgcct gcctggacaa ggcgctggcg
    14881 agcgccatga ccgacttcaa gaaggtcggc gtcttcctgc tcgacatcga caatttcaag
    14941 gacgtcaacg acctgatggg ccatcatgcc ggtgacgagc tgttgaaaag ctttgcctct
    15001 cgcctgaagg aaatcttcgc cggcgacggg gtggtggcgc ggctgggcgg cgacgagttc
    15061 gccatattga tcgagaatgt cgaaagccgg cagcagcttg ccgatctcgc caatcgcgtc
    15121 ctcaccattc gggagacgct gttcgccgcc gggcgctcgc tcgaatgccg cggcagcatc
    15181 ggcgtggccg cattccccga ggacggccgg gtcgcgacgg aactgctgcg ccatgccgac
    15241 ctggcgcttt atcgcgccaa gtcgctgggc cgggggcgca tgcagatgtt cgaacagtcg
    15301 ctgctggagg acatgcagga gcgcgtggcc atgatcaacc gggcgcggac cgccgtgcgc
    15361 gacggcacga tcatcagcta ttatcagccc aaggtgtcgt tgcagacggg cgaactggtc
    15421 gggttcgagg cgctgctgcg gtggcgcgac agttgcggca ccatccgctc gcccgccgaa
    15481 atctacgcgg cgttcgacga tcatgacgtc gccgacatga tcggccagac gatgaccagc
    15541 caggtgttcg ccgacatggc cgcatggcgt gcgcgcgggc tgacgctggg gcatgtcgcc
    15601 atcaacgtgt cctcggccga attgcggcgg gaacgctttg ccggacgctt gatcgagacc
    15661 atggaccgct tctccatcgc gcccgattcc atagagatcg agatcaccga aggggtgttc
    15721 ctgggcgcgg ggtcggatac ggtgcgccgt tccatcgacg aactgcacat gtgcaacatc
    15781 ccgctggcgc tggacgattt cgggaccggc ttcgcctcgc tttcccattt gcggtcgctg
    15841 cccgtcagca cgctgaagat cgaccgttcc ttcgtcagcg gcgtgacggc gcgcgaaagc
    15901 gacgccgcca tcgtttccgc gctgatcacg ctgggccgcg cgctcaacat gaaggtggtg
    15961 gcggaaggcg tcgaggaagc ggaccagtcg gtcaagctgc gcgaactggg ctgcgactat
    16021 gcccagggtt tctatttcgg ccgtcccgcg ccgtcggaga atattcccgc gctgatccag
    16081 tcctggagcg agaatagcgc catcatcacc ctgaaccggc gggccgcgcc ctggcctccg
    16141 cgcgggatgc gcggggaagg ccgcgcggac tcgctgaccg cctgagggaa gaccagatcc
    16201 cggtcaggtg aggcgcagcg acgtggtgcg gcttcaatcc gctcgcgcct ggagcacgct
    16261 gcgccagatc ggacgcgggt cgcgtgctcc agctttctgt tgtcccattc tttcaggcgg
    16321 aaaaccggtt ccaacccgtc ggcgggctca gggcagcttt tccgcacgat tggctctagc
    16381 cgttgacgat ggtgccccca ttgggatgca gcacctgccc cgacatgtag ctggcgtcat
    16441 cgcaggcgag gaagaggaag gacggggcga cttcattggg ctggcccggc ctgcccatgg
    16501 gcgtgctttc cccgaaatgc tccagctttt ccggacttgc cccgccgctg ggattgagcg
    16561 gggtccagat cggccccggc gcgacggcgt tcaccctgat gccgtccccc accagatttt
    16621 cggacagcga ccgggtgaag gcggtgatcg cccccttggt gctggaatag tcgagcagtt
    16681 ccttcgaccc ctgatacatg gtgacggagg tgcagttgac gatcgccgcc ccgcgcttca
    16741 gatgcggccg caccgcctgc gtcaggaaga acatggcgaa gatgttggtc tggaaggtgc
    16801 ggcgcagctg ttcctcgctg atgtcggtga tgtcgctgtc gggatgctgc tcgcccgcat
    16861 tgttgacgag gatgtcgatc cgcccgaact gctccaccac ctgcgccacg gcccgctggc
    16921 agaagtcccg gtcgcccagg tcgcccgcga tggtgagcgc ccgccgccct tccgcccgga
    16981 cgatcccggc ggtcttttcc gcgtcgtcat gttcgcagag gtagaagatc gcgacatcgg
    17041 ccccttcgcg ggcatagagc gccgcgaccg cccgcccgat tccgctgtcg gcgccagtga
    17101 cgatcgccac cttgcccgcc agccggccgg agccgggata gcgcggttcc cattccggct
    17161 tgggctccag ccggctttca tggccgggca ggccatcctc atggatcatc tcttcggtat
    17221 cgggcatcgc aaatctcctt tccccgaaga acacattgcc tgctggggag ttcattggct
    17281 ggagcccggt tcggcgcgtg gatggggcgg atggagacat gcgatggttc tgaaagccct
    17341 ggccctcaac tgcaccctca aggcggggga aggcgaatcc agctcgaccg acgcgatgat
    17401 cgcggtgctg gcgaaggccc ttgccgccca tgatgtcgaa ctcaccggca cggtgcgggt
    17461 cgcggcgctc gacatcaggc ccggcgtgac gtccgatgaa ggagagggcg acgcctggcc
    17521 ggcgttgcgc cgcaggatat tggaccatga catagtgatc ttcggcggcc cgatctggct
    17581 ggggcagatc agcagcgtcg ccaagcgggt gctggaacgc atggacgcct ttctgggcga
    17641 aaccgatgac cggggccgca tgccgagcta tggcaaggtt gcggtcgcgg cgattgtcgg
    17701 caatgaagac ggggcgcatt tttcgaccgc gcaatggttt caggcgctga acgatgtcgg
    17761 ctggacggtt ccggccacgg ccgcctgcta ttgggtgggg gaagccatgg gctcgatcga
    17821 tttcaaggat ctggggcagg tgccggagaa ggtggagaag accgcgaaga tggtggcggg
    17881 caatgcggcg catctggccg gcctgctccg gtcctccccc tatccgggct gaacccaggt
    17941 ggcgaaaacc ggccgcgtcg cgcatatccg gaaaaatatt gtcctttacg gcgcgctgct
    18001 ggccaatatc ggcattgcgg tcgccaaatt cgtcgcctcg gccctgaccg gctcctcctc
    18061 catgctgacg gagggggtgc attcgatggt cgacagcggc aaccagttgc tgctgctcta
    18121 tggtcaggcc agggcgaaga agcccgccga cgccgcccat cccttcggct atgggcggga
    18181 gctgtatttc tgggccttcg tcgtcgccat cctgatcttc gcggtcggcg cgggcgtatc
    18241 catctatgaa ggctggctcc atatccggca gccggagccg ctgcgcgacc ccgccgtcaa
    18301 ctacatcgtc ctggccatcg ccttcctgat ggagggcgca tcctggacca tcgccgtgcg
    18361 ggaattcgga cgcaaacgcg gccccagcag ttggtggcaa tcgatccgcc ggtcgaagga
    18421 cccggccggc ttcatcgtcc tgttcgagga cagcgccgcg ctgatcgggc tgatcgtggc
    18481 ggccatcggc gtctgggcca gccattattt cggcaatgcg cggctggacg gcgtcgcctc
    18541 catcgtcatc gggctggggc tgggcgcggt cgcggtgctg ctggcgcggg aggccaaggg
    18601 cctgctgatc ggggagagcg ccgaccgggc catcatcgac gcggtctggg cgctgctcga
    18661 ccggcggccg gagatcaccg ccgtcaatca catccgcacc atccacaccg cgcccgacgc
    18721 ggtgttcgtg gcgatcagcg ccgatttcgc cgacgatctg cgcatgggcc gggccgaaag
    18781 cctgatcgag gagatggaaa gcgagatgaa gcgggcgatt cccgaactca cctccatcta
    18841 tattcgtccg gaaaagcggg aggacgccct ggtccagccg cgcgcttccg cctgacggcc
    18901 ggcccgcccc gcctgttcgc agccttccac gtccatattc cgtcaattgg ccccttgacc
    18961 atctgatgac gatcgtcatc taacgccggt cgatcgatcc gggaggaagg ccttcatgct
    19021 gtcagcgact ctcgcccgcc aaatgggcac gcggcaaatc cattatggat gggcggtgct
    19081 ggccgcgacc ttcttcacca tgctggtcgt cgccggggcc gtgggcgcgc ccggcgtgtt
    19141 catcatcccc ctgcaaaagg aatatggctg gagttcggcg gatatttccg gagcgctggc
    19201 gatccgtttc ctgctgttcg gcgggatggg cccgttcgcc gccgccttca tgaaccgctt
    19261 cggcgtgcgg cggatgatgc tgatctcgct gtccatcatc gtcggcgggc tgctgctgtc
    19321 gatgggcatg acccgattgt ggcatctcgt cctgctgtgg ggcgtcgtca tcggcgtcgg
    19381 aaccgggctc accgccatgg tgctgggcgc caccgtcgcc acgcgctggt tcgcccacag
    19441 gcgggggctg gtcatggggc tgctgtcggc cagcaccgcc accggtcagc tggccttcct
    19501 gccgctgctc gccgcgctga cggagcggtt cggctggcgc gcgtcaatcc tgctggtgtg
    19561 cggcgcgatc ctgctggcgg cgatggtcgt gctgctgctg atgcgcgacc gtcccgccga
    19621 cctcggcctg ccgccctatg gcgagagcga ggtgcatccc gccccgccgc agcccgccag
    19681 cttcggcgcc ctgttgatga gcccgctccg catcttggcc gatgccgcgc gggtgcccag
    19741 cttctggata ttgttctttt ccttctacat ctgcggcgcc agcaccaacg ggctggtcca
    19801 gacgcatttc atcgcgcttt gcggcgacta tgggctggcg gcggtgggcg cggcgtcgat
    19861 gctggcgatg atggggctgt tcgatttcgc gggcacgctg gcgtcgggct ggctgtcgga
    19921 ccggttcgac aatcgctggc tgctgttctg gtattatggg ctgcgcggcc tttcgctgct
    19981 ctatctgccg ttcagcgact tctcgctcta cagcctgtcg gtcttcgcga tgttctacgg
    20041 cctggactgg gtcgcgaccg tgccgccgac ggtcaagctg acggcgcagc gtttcggacc
    20101 ggagcgggcc aatgtcgtgt tcggctggat cttcgccggg catcagctcg gcgcggcgag
    20161 cgcggcgctg gcgggcggcc tttcccgcac cgtctggcaa agctatatgc ccgccttcgt
    20221 cgcggcgggg atattgtgcc tgatcggggc ggggctggtg ctgctgatca accgcgcgcg
    20281 gagcaagacc ttcgtcctcg cctgaccggc tgtatggaga ggcttggatg ctgcaaggaa
    20341 aaatcgccct cgtcaccgga gccggacgcg gcctggggcg cgagatcgcg ctgggcctgg
    20401 ccggggccgg cgcgcatgtc ctgctccatg gccgaaatat cgagcagctt gaggcgaccg
    20461 ccgccgccat cgccgcctcg ggcgggacga gcgcgccgct gatcttcgac ctggaggatg
    20521 gcgaagcgct gcgggcggcg ctcggcccct gcggcccgat cgacatattg gtcaacaatg
    20581 caggccatcg cgaccgcaga ccgattggag aactggaccg gcccgcggtg cggcggatgc
    20641 tggagatcaa tctggtcgcg cccttcgacc tcgcccgcac catcgcggcc gggatgaagg
    20701 agggcgggcg gatcgtcaac gtcacgtcca tcgcgggcca gatcgcccgg tccggcgacg
    20761 ctgcctacac catggcgaag ggcgggctgg ac
//
