LOCUS       NZ_CP010954            20921 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Sphingobium sp. YBL2 chromosome, complete genome.
ACCESSION   NZ_CP010954
VERSION     NZ_CP010954.1
KEYWORDS    RefSeq.
SOURCE      Sphingobium sp. YBL2
  ORGANISM  Sphingobium sp. YBL2
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingobium.
REFERENCE   1  (bases 1 to 4766421)
  AUTHORS   Yan,X.
  TITLE     The analysis of one genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4766421)
  AUTHORS   Yan,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2015) College of Life Sciences, Nanjing
            Agriculture University, Weigang Street #1, Nanjing, Jiangsu 210000,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2014
            Assembly Method                   :: Celera Assembler v. 8.0
            Assembly Name                     :: YBL2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina MiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000943805.1-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 04:34:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,219
            CDSs (total)                      :: 5,153
            Genes (coding)                    :: 5,086
            CDSs (with protein)               :: 5,086
            Genes (RNA)                       :: 66
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 25 of 67
            Pseudo Genes (incomplete)         :: 53 of 67
            Pseudo Genes (internal stop)      :: 4 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 625238
            Orig. end                         :: 646159
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP010954.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from yanxin@njau.edu.cn.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20921
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20921
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20921
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10921](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10921)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(245..2542)
                     /locus_tag="TZ53_RS03035"
                     /old_locus_tag="TZ53_03030"
     CDS             complement(245..2542)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020817678.1"
                     /locus_tag="TZ53_RS03035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03030"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_044660373.1"
                     /transl_table=11
                     /translation="MMGLAVVPGDAAERVLAAQLRSADHVALLRQAMNLFGLLFLWQVF
                     GDHGSVPGLMVWSAALVLSMAVGAILRRRRNGAAASATDLRVHGFTGLLHGLVWAACMM
                     TLSSGHGAAQLVAHWTLISCIMVCGAISYAATPLAATGFLLPCIVGLGALFDPRDQTPL
                     LALATSYALSLLVGCFLYARTFARQHSASVQLEEKSEVVSLLLREYEHGASDWLWQTDP
                     ARRLSGVSPRLAEMLGRTPAEVEGVLLVQLLAGNAWESGLFPTELHALADHLKRRESFS
                     NIVLPVELEGDVRWWELSASPRYDEGGAFLGFRGVGSDITEQKESAERIAQLARFDPLT
                     GLPNRTHLRDVLDQAMGGGGTAGAGRGGCAFLMIDLDRFKAVNDTLGHQIGDKLLTQVA
                     RRLRHICSGAEFCGRIGGDEFAVVIPQLGDNHGVDRLAARIINGLSAPYQVDEHTLYVG
                     ASVGSAVSPQDGHESEALIRSADLALYRAKGDGGGVHCAYEPQLHAQAEERRQLELALR
                     DALEKNQLHVLFQPVVEAQAGIVVGFEALVRWTHPDMGPISPAKFIPVAEEARLIGPIG
                     EWVLRTACKEAACWPDGVRIGVNVSAEQLVHPSFVGAVVSALAQSGLEARRLELEVTES
                     VFVNADTGALKILDQLRGLGVRLSLDDFGTGYSSLGYLSRTRFDTIKIDRSFVVGAANN
                     RAESLAIIRAVVTLADSLGMATTAEGVETEAELAMVRGLGCRKVQGFYFGRPMPAADAA
                     ALFPGHQVRARA"
     gene            complement(2701..4461)
                     /locus_tag="TZ53_RS03040"
                     /old_locus_tag="TZ53_03035"
     CDS             complement(2701..4461)
                     /NRPS_PKS="Domain: CAL_domain (184-494). E-value: 6.3e-84.
                     Score: 273.6. Matches aSDomain:
                     nrpspksdomains_TZ53_RS03040_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004210350.1"
                     /locus_tag="TZ53_RS03040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03035"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_044660374.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 8.5e-163, bitscore:
                     541.4, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1e-78, bitscore:
                     262.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLGDTNMTGSQSMMAPTPTTDDLPRRFSDFETLGEALDYAATGR
                     RGLNFHDARGNLARPYPFAELREDAVACAHRLIAHGVKPEDRVALVAETGPDFAQLFFG
                     IVYAGAWPVPLPLPTSFGGKESYIDQLNVQLSSCDPMLFLFPKELEEMAGESGRQKAVE
                     SIAFEDFIAREAVPCDLPQAKGEEIAYLQYSSGSTRFPHGVAVTHHALLSNLAAHSHGM
                     ELVESDRCISWLPWYHDMGLVGCFLSVVANQVSTDYMKTEDFARRPLAWLDLISRNEGT
                     SISYSPTFGYDICARRMSSQTKAQDRFDLSRWRLAGNGADMIRPDVMQSFVDAFGDAGF
                     SPKAFLPSYGLAEATLAVTIMPPGEGIIVELVEETDLSGGDATEGRPQRFRSIVNCGKP
                     ARDMVVEIRDEDGAKLNERQIGKVWTTGPSLMVGYFRDPEATDACMVDGWLDTGDMGYL
                     SDGYLYIVGRAKDMIIINGKNHWPQDIEWAVEQLPGFKQGDIAAFAITTPGGEEAPAVL
                     VHCRTSDNDERTRLRDQIRERVRAITGMNCVVELVPPRTLPRTSSGKLSRSKARNLYLT
                     GEIRPYDIAA"
     aSDomain        complement(2980..3909)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TZ53_RS03040_CAL_domain.1"
                     /evalue="6.30E-84"
                     /label="TZ53_RS03040_CAL_domain.1"
                     /locus_tag="TZ53_RS03040"
                     /protein_end="494"
                     /protein_start="184"
                     /score="273.6"
                     /specificity="Minowa: Acetyl-CoA"
                     /tool="antismash"
                     /translation="GEEIAYLQYSSGSTRFPHGVAVTHHALLSNLAAHSHGMELVESDR
                     CISWLPWYHDMGLVGCFLSVVANQVSTDYMKTEDFARRPLAWLDLISRNEGTSISYSPT
                     FGYDICARRMSSQTKAQDRFDLSRWRLAGNGADMIRPDVMQSFVDAFGDAGFSPKAFLP
                     SYGLAEATLAVTIMPPGEGIIVELVEETDLSGGDATEGRPQRFRSIVNCGKPARDMVVE
                     IRDEDGAKLNERQIGKVWTTGPSLMVGYFRDPEATDACMVDGWLDTGDMGYLSDGYLYI
                     VGRAKDMIIINGKNHWPQDIEWAVEQLPG"
     CDS_motif       complement(3004..3066)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TZ53_RS03040_0003"
                     /evalue="5.20E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="TZ53_RS03040"
                     /protein_end="486"
                     /protein_start="465"
                     /score="12.8"
                     /tool="antismash"
                     /translation="VGRAKDMIIINGKNHWPQDIE"
     CDS_motif       complement(3133..3204)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TZ53_RS03040_0002"
                     /evalue="1.10E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="TZ53_RS03040"
                     /protein_end="443"
                     /protein_start="419"
                     /score="14.7"
                     /tool="antismash"
                     /translation="IGKVWTTGPSLMVGYFRDPEATDA"
     CDS_motif       complement(3838..3897)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TZ53_RS03040_0001"
                     /evalue="1.90E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="TZ53_RS03040"
                     /protein_end="208"
                     /protein_start="188"
                     /score="17.4"
                     /tool="antismash"
                     /translation="AYLQYSSGSTRFPHGVAVTH"
     misc_feature    4535..4548
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.35"
                     /tool="antismash"
     gene            4612..5136
                     /locus_tag="TZ53_RS03045"
                     /old_locus_tag="TZ53_03040"
     CDS             4612..5136
                     /GO_process="GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019053747.1"
                     /locus_tag="TZ53_RS03045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03040"
                     /product="RecX family transcriptional regulator"
                     /protein_id="WP_044660375.1"
                     /transl_table=11
                     /translation="MTGKRPPAPLDEEAMRELALRYVARFATSRAKLLAYLGRKIKERG
                     WGGEDPADPQALVDRLSELRYVDDAGYAVMKSGALSRRGYGARRVAETLRADGIAEADR
                     VEAHAQTQRESWSAADRFARRKRIGPYAQERPDLKQREKWIAAFLRAGHDYATARRWTD
                     AAPGEVPEADE"
     gene            5186..5704
                     /locus_tag="TZ53_RS03050"
                     /old_locus_tag="TZ53_03045"
     CDS             5186..5704
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013041405.1"
                     /locus_tag="TZ53_RS03050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03045"
                     /product="DUF192 domain-containing protein"
                     /protein_id="WP_025547498.1"
                     /transl_table=11
                     /translation="MKPFLLLLLAILPAACSPSAPKAENTAAPTATGQTTLLPLTIHTA
                     KTAHRFTVELALTEQQQEQGLMFRKSLAPDSGMLFPMSPPRTASFWMKNTLIPLDMLFI
                     HTDGSIAFLKANAAPYSREPVSAGIPVAAVLELRGGRAAELGIREGDRVTWGDCDRPSS
                     SNPLNFCPR"
     gene            5754..6152
                     /locus_tag="TZ53_RS03055"
                     /old_locus_tag="TZ53_03050"
     CDS             5754..6152
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0010257 - NADH dehydrogenase complex
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007688672.1"
                     /locus_tag="TZ53_RS03055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03050"
                     /product="NADH:ubiquinone oxidoreductase subunit NDUFA12"
                     /protein_id="WP_025547500.1"
                     /transl_table=11
                     /translation="MGILGKIFTWWDGATIGTSLYTSRKGTKVGEDHQGNVYYEGGTDP
                     NGLTRRWVIYNGANDASRVPAEWHGWLHHSIEGAPESFLPPPRIWERDFTPNATGTAQA
                     YRPTGALEKGGLRQKATGDYEAWSPDAS"
     gene            6380..>6550
                     /locus_tag="TZ53_RS27820"
                     /pseudo=""
     CDS             6380..>6550
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021444.4"
                     /locus_tag="TZ53_RS27820"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF2155 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKPGEALRVGDAIVRLQACETTAPWENVQETGAFVQLDVRSTADN
                     KWRRNFSGWLFR"
     gene            complement(6586..7350)
                     /gene="aat"
                     /locus_tag="TZ53_RS27825"
                     /old_locus_tag="TZ53_03060"
     CDS             complement(6586..7350)
                     /EC_number="2.3.2.6"
                     /GO_function="GO:0008914 - leucyl-tRNA--protein transferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="aat"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010335650.1"
                     /locus_tag="TZ53_RS27825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03060"
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="WP_044660376.1"
                     /transl_table=11
                     /translation="MTIDPLVLLQAYAIGVFPMSDDREAEEVYWIEPKRRAIMPLDGFH
                     ISHSLAKTIRRERFRVTANRDFTGIVRLCAEAAPDRPSTWINHPIERAYRHLHEIGFAH
                     SVEVWEGEELVGGLYGVALGRAFFGESMVSRRADASKVALAWLTARMRFGGFTLLDCQF
                     MTDHLRSLGAIEISQRDYLQSLAGALDGVALGAGRGVLAAGSGVWAELAFSPLAGDALA
                     RAPSDTSPLSPSFTVSGPVSGHDIVQLLTQTS"
     misc_feature    complement(7414..7426)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.7"
                     /tool="antismash"
     gene            complement(7467..8501)
                     /gene="queA"
                     /locus_tag="TZ53_RS03070"
                     /old_locus_tag="TZ53_03065"
     CDS             complement(7467..8501)
                     /EC_number="2.4.99.17"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="queA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007688680.1"
                     /locus_tag="TZ53_RS03070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03065"
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="WP_044660377.1"
                     /transl_table=11
                     /translation="MRVDLFDFDLPPESIALRPASPRDAARLLLVPGDAPFQDRIVRDL
                     PDLLRAGDVLVFNDTRVIPAQLEGMRGQARVGATLHKRLGLRQWQAFLRNAKRVRDGDW
                     IDFGNGVTAVAGPRDEDGGVTLRFEGEEPVELLLERAGRMPLPPYIASKRPTDERDRSD
                     YQTMFAREDGAVAAPTAALHFTPELMAAVEKAGVRTETLTLHVGAGTFLPVKADDTDDH
                     RMHAEWGRIDQATADRLNAARAAGGRLIAVGTTSLRLLESATGEDGIIRPFADETRIFI
                     TPGYRFRAVDGLMTNFHLPKSTLFMLVSALMGTEKMLSVYRHAIDRGYRFYSYGDSSLL
                     LPQP"
     gene            complement(8613..9389)
                     /locus_tag="TZ53_RS03075"
                     /old_locus_tag="TZ53_03070"
     CDS             complement(8613..9389)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007710026.1"
                     /locus_tag="TZ53_RS03075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03070"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_044660378.1"
                     /transl_table=11
                     /translation="MRFTSALKTVAIGFALYASSSAALAQGGGGRNAEEMKKEEAAVRA
                     EQAAKQLGLDPASKLPPATVPVDPQNVWDLDLSSGGRVRIQLRPDIAPGHVERIKELTR
                     QGFYNGLKFHRVIPGFMAQGGDPKGDGTGGSTLPDLKAEFNPMPHLRGTVSMARAQSED
                     SANSQFFIVFLPRMQLDKKYTVFGRVIEGMQYVDAIHQGEPPADPTIILQASIESDGRP
                     PVTALPTPPAPPTPSIVAPLAKKPAPARKPAAPKKK"
     misc_feature    9447..9459
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.62"
                     /tool="antismash"
     gene            complement(9484..9996)
                     /gene="coaD"
                     /locus_tag="TZ53_RS03080"
                     /old_locus_tag="TZ53_03075"
     CDS             complement(9484..9996)
                     /EC_number="2.7.7.3"
                     /GO_function="GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004211217.1"
                     /locus_tag="TZ53_RS03080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03075"
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="WP_025547507.1"
                     /sec_met_domain="CTP_transf_like (E-value: 9.1e-19,
                     bitscore: 66.1, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQRVGVYPGTFDPITLGHMDIIRRGAKLVDKLVIGVTTNISKS
                     PMFSDDERLDMVRRECAGIDTEIVVTGFNSLLMDFAESQGASVIIRGLRAVADFEYEYQ
                     MAGMNQQINGRVETVFLMADVSLQPIASRLVKEIALYGGPIHKFVSPAVREEVEARVAA
                     IGLKGQG"
     gene            complement(10001..10921)
                     /locus_tag="TZ53_RS03085"
                     /old_locus_tag="TZ53_03080"
     CDS             complement(10001..10921)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013041408.1"
                     /locus_tag="TZ53_RS03085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03080"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_044660379.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.9e-56, bitscore:
                     188.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGPDSASPRSIGLVADRAAAVAADIDRLFDALLAVPDDPRRRLH
                     EAMRHAAMGGGKRLRPLLVQAASDLFNISRDSALRVGVAVECIHVYSLVHDDLPAMDDD
                     DLRRGKPTVHKAFDEASAILAGDCLHDLAFEVLADEETHPDPFVRVELVKALAVASGTS
                     GMAGGQMMDLEAEKTSFDLPTVTRLQQLKTGALIGFCVDAAAIMARIPPEGRTRLHGYA
                     RDIGLAFQIADDLLDVEGDAVLAGKALGKDAAAGKETFVSLLGVERAREQGRLLVEQAK
                     AHLHGFGPEADLLRAIADYIVERDR"
     gene            complement(10948..11208)
                     /locus_tag="TZ53_RS03090"
                     /old_locus_tag="TZ53_03085"
     CDS             complement(10948..11208)
                     /EC_number="3.1.11.6"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007710023.1"
                     /locus_tag="TZ53_RS03090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03085"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_025547511.1"
                     /transl_table=11
                     /translation="MAQDSMTHEGDPSQMSFEDALRALESIVRRLESGDVPLDESISLY
                     SQGEELRKRCMERLQAAEARIAKLTIDAGGAVTGAQPFGSD"
     misc_feature    11371..11387
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            11376..11756
                     /locus_tag="TZ53_RS03095"
                     /old_locus_tag="TZ53_03090"
     CDS             11376..11756
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019516111.1"
                     /locus_tag="TZ53_RS03095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03090"
                     /product="hypothetical protein"
                     /protein_id="WP_025547512.1"
                     /transl_table=11
                     /translation="MKYHLPLISVAALALLSACNKNDEPEVVGGPADPMAEKLANAAPV
                     ELPPMVKESHQYRCKDNSLIFVDFMSDDKTVNVRTEKDGAPTKLTAAEAGKPFEGGGFK
                     VEGSGKQITATLPGKSALSCKA"
     gene            complement(11917..12345)
                     /locus_tag="TZ53_RS03100"
                     /old_locus_tag="TZ53_03095"
     CDS             complement(11917..12345)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009821181.1"
                     /locus_tag="TZ53_RS03100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03095"
                     /product="DUF805 domain-containing protein"
                     /protein_id="WP_025547513.1"
                     /transl_table=11
                     /translation="MEWMLLPLRRYAKFSGRARPREYWMFVLFLLLCYIGVAMVEGILG
                     LSTTDHWFQRGPWWAGAGYSTRGGPLTGLFTLAMIIPHIAVSVRRLHDTDRSGWWLLIV
                     FFPIIGSIVLLIFFIMSGTRGPNRFGPDPVEVGEPELR"
     gene            12451..14628
                     /gene="purL"
                     /locus_tag="TZ53_RS03105"
                     /old_locus_tag="TZ53_03100"
     CDS             12451..14628
                     /EC_number="6.3.5.3"
                     /GO_function="GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="purL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017499860.1"
                     /locus_tag="TZ53_RS03105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03100"
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="WP_044660380.1"
                     /transl_table=11
                     /translation="MSSTASQITPQVVADHGLSPEEYDRVLNALGREPNLTELGIFSVM
                     WSEHCSYKSSRIHLKKLPTEGPQVICGPGENAGVVDIGDGQAAIFKMESHNHPSYIEPY
                     QGAATGVGGILRDVFTMGARPVANMNALRFGRPDHPKMKHLISGVVHGIGGYGNCVGVP
                     TVGGEVNFHPAYDGNILVNAMTVGVAETDKIFYSAASGIGNPIVYVGSKTGRDGIHGAT
                     MASADFGDDADAKRPTVQVGDPFTEKLLIEACLELMASDAIVAIQDMGAAGLTSSSVEM
                     ASKGGVGIQLNMDDVPQRETGMTAYEMMLSESQERMLMVLQPGKEAFAEAIFRKWELDF
                     AVIGHVTDTGRMVLVHKGETVCDIPLAPLADDAPLYDRPAMAKDEYKAWSGVQPLGEIS
                     ESADIGADLVRLMGSPDIASRRWIWEQYDHMVGADTVQRPGGDAAVVRVHGTRKGIAIS
                     TDCTPRYCYADPYEGGKQAIAECYRNISAVGATPLAVTNCLNFANPQRPEIMAQFTGCL
                     EGMGEACRALDFPIVSGNVSLYNESKATGGGSAILPTPAIGGIGLLQDIDGMATVAFKN
                     EGDAIWLIGGEGSHLGQSIWLREIAGREAGEAPKVDLAAERAHAETVRALIAEGKVNAV
                     HDISDGGLLVAVTEMALAGKIGAELSIALTTASAFGEDQGRYIVAAAQGVDIPGALRIG
                     TTGGDKVAGVALADLRSAHEGFFPALMDAEL"
     gene            14712..15881
                     /gene="purT"
                     /locus_tag="TZ53_RS03110"
                     /old_locus_tag="TZ53_03105"
     CDS             14712..15881
                     /EC_number="2.1.2.-"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="purT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011414816.1"
                     /locus_tag="TZ53_RS03110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03105"
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="WP_044662818.1"
                     /sec_met_domain="ATP-grasp (E-value: 2.7e-56, bitscore:
                     187.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.8e-08,
                     bitscore: 32.1, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFTAKILLLGSGELGREFVISAKRLGAQVIACDSYAGAPAMQVA
                     DGFEVFSMLDADLLAKAIEKHRPDFVVPEIEAIRTEVLADFEARGVTVVPSARATIMTM
                     NRDRIREVAAVELGLRTSRYRYAETLEEVRAGAAHTGLPCVIKPVMSSSGKGQSTVRTI
                     EELEAAWDYAVANMRGDRSRVIVEEFIAFDYEITLLTVRSRDGVSFCPPIGHRQERGDY
                     QESWQPTPMSGGALAAAQDMARKVVDNLGGYGIFGVEFFVKGEDVIFSELSPRPHDTGM
                     VTLISQNWSEFDLHARAIMGLPVPEVTLHGAAASAVILADRESDDFRFEGLAEALSTPG
                     GEVDLRLFGKPTTRHYRRMGVALARAIDADQARAVAAEAASKVRIIHGR"
     gene            16007..16726
                     /locus_tag="TZ53_RS03115"
                     /old_locus_tag="TZ53_03110"
     CDS             16007..16726
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013041411.1"
                     /locus_tag="TZ53_RS03115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03110"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_044660381.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 2.1e-06, bitscore:
                     25.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITRRVTVHEGPGGQFESMAVFDDAAAAPRPAILLFPNVLGTKE
                     ADFAYAEKVAAIGYTVLVADVFGQGKRTSRADPDMGRYMAELNDDRTLLRDRTNAAHAL
                     LKSLDEADESRTAAIGFCFGGKCVLDLARSGADIAGGVSFHGVYDAPPLPHAKITARLL
                     ICHGWDDPIAPPEATVALAKELTEAGCDWQIHAYGHTGHAFTDHDAKMPERGLAYNPEA
                     DRRSFRAMADFLGDLFG"
     gene            complement(16744..17874)
                     /locus_tag="TZ53_RS03120"
                     /old_locus_tag="TZ53_03115"
     CDS             complement(16744..17874)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017499327.1"
                     /locus_tag="TZ53_RS03120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03115"
                     /product="M14-type cytosolic carboxypeptidase"
                     /protein_id="WP_044660382.1"
                     /transl_table=11
                     /translation="MSISITSAFDSGNIRVLSISATSAGVRAELEIVKDRQSDFYQWFH
                     FRVAGVAGREVELAIVNCGASAYPDGWPGYKARYSEDRENWLLADTGYADGTLTIRLSP
                     DSNAVWLAYFAPYSMERHHDLVAWAASQPGVEHRELGLTLDRQPLDLLVLGEGPKKVWL
                     YARQHPGESMAEWWMEGALERLCDEEDAVARLLRREATFYIVPNMNPDGSRRGHLRTNA
                     VGINLNREWHEPSMEKSPEVFLVRGAMDEVGVDFAMDVHGDEAIAAVFLAGFEGIPSIT
                     ERKSALYRRYRDTLAARTPDFQTRKGYPTAPAGKANLSMSTNQLAERFGAVAMTLEMPF
                     KDNDDLPDADFGWSPARSIQLAKDCLGVLAEMIDEI"
     gene            complement(17871..18485)
                     /locus_tag="TZ53_RS03125"
                     /old_locus_tag="TZ53_03120"
     CDS             complement(17871..18485)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007688695.1"
                     /locus_tag="TZ53_RS03125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03120"
                     /product="DUF4136 domain-containing protein"
                     /protein_id="WP_083198934.1"
                     /transl_table=11
                     /translation="MSNPSMLKKIVLPSLLALGLSGCATAVPPVEVTRFHIDDPARNGT
                     IAVEEMAGNPDVGLEFRTYAAAIEQELQRVGFTTAAQGAKSDYVALVSFRRTFREPESY
                     GANGKPVSVGVGGAVGSGGYSGLGLGIGINLSGKPKGQVFTELQVQIRRRADSTTIWEG
                     RAQTGAREGTPASQPGLAAQKLATALLGGYPGESGRTITVR"
     gene            18694..18819
                     /gene="ykgO"
                     /locus_tag="TZ53_RS03130"
                     /old_locus_tag="TZ53_03125"
     CDS             18694..18819
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="ykgO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012177066.1"
                     /locus_tag="TZ53_RS03130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03125"
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="WP_004210176.1"
                     /transl_table=11
                     /translation="MKIRNSLKSLKGRHRDNRVIRRRGRTYVINKTNRRFKARQG"
     gene            18823..19449
                     /locus_tag="TZ53_RS03135"
                     /old_locus_tag="TZ53_03130"
     CDS             18823..19449
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020817668.1"
                     /locus_tag="TZ53_RS03135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TZ53_03130"
                     /product="HAD family phosphatase"
                     /protein_id="WP_025547522.1"
                     /sec_met_domain="HAD_2 (E-value: 5.8e-13, bitscore: 47.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADIAAVVFDVGNVLYHWTPRVLYERLIDDDRALDAFLRDVVTLD
                     WHFQHDQGRPFAETSAELIARHPEHAALIRLWGEKFIDSVGPAVEGMPEIVLELHEGGI
                     PLFAITNFSHEFWAPFHARESALFAPFRDIVVSGAEKLVKPDPAIYRLALERFGLSAEQ
                     ALFIDDREENVLAAEAEGMRGHLFRDAATLRRELAELALLRSPTV"
     misc_feature    complement(20769..20780)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.08"
                     /tool="antismash"
ORIGIN
        1 atcgccggcc tttcggagcc tggcgcgcgg ccctcgcggc gatcgaaggc tcccggccat
       61 tatcgcaagc gcggggatgc tttcccgagg cgatggaatt acggatcgag agcggcggat
      121 aaggggcggg ccgagagcag catgggggcg aacatgctgc cgcgacggac gggcaagact
      181 gcgccatgtt cgatggactc cggagcgcat cttgggtcgc gtccttccat cgcggcgatg
      241 aagcctaggc ccgggcgcgc acctgatgtc cggggaagag cgccgccgcg tcggccgccg
      301 gcatgggccg cccgaaatag aagccctgca ccttgcggca gcccaggccc ctgaccatgg
      361 ccagttcggc ctccgtttcg acgccctccg ccgtggtcgc catgcccaga ctgtccgcca
      421 gcgtgaccac cgcgcggatg atcgccaggc tttccgccct gttgttcgcc gcgcccacga
      481 cgaagctgcg gtcgatcttg atcgtgtcga aacgtgtgcg gctgagatag ccaagcgagg
      541 aatagcccgt cccgaaatcg tcgagcgaca gccgaacgcc cagcccccgc aactgatcga
      601 gtatcttgag cgccccggta tcggcgttga cgaacacgct ttcggtgact tccagctcca
      661 gccgccgcgc ctccagcccg ctctgcgcaa gggcggacac caccgcaccg acaaagctcg
      721 gatggacgag ctgctcggcc gagacattga ccccgatgcg cacgccgtcg ggccagcatg
      781 ccgcttcctt gcaggcggtc cgcagcaccc attccccgat cggtccgatc aaccgggctt
      841 cttccgcgac cggaatgaat ttggctggcg agatcggccc catgtccgga tgggtccagc
      901 gcaccagcgc ctcgaacccg acgacaatgc ccgcctgcgc ctccaccacc ggctggaaca
      961 gcacgtgcag ctggttcttc tccagcgcgt cgcgcagcgc gagttccagt tggcggcgct
     1021 cctccgcctg cgcatgcaat tgcggttcat aggcgcaatg cacgccgccg ccatcgccct
     1081 ttgcgcgata gagggcgagg tccgcgctgc ggatcagcgc ctccgattca tggccatcct
     1141 gtggcgacac cgccgacccg acggatgcac cgacgtaaag cgtatgttcg tccacctgat
     1201 aaggggctga aaggccgttg atgatccggg ccgcgagcct gtcgacgccg tgattgtccc
     1261 ccagttgcgg gatgacgacg gcaaattcgt cgccgccgat gcgcccgcaa aattccgcgc
     1321 cggaacagat atgccgcaat cgtcgcgcca cctgggtcaa cagcttgtca ccgatctggt
     1381 ggcccagcgt atcgttcacc gccttgaacc ggtccaggtc tatcatcagg aaggcgcagc
     1441 cgccgcgccc tgcgcccgcc gtcccgccgc cgcccatggc ctgatccagc acatcgcgca
     1501 gatgcgtgcg gttgggcagg ccggtcaacg ggtcgaaccg cgcaagctgc gcgatccgtt
     1561 ccgccgattc cttctgttcg gtaatatccg agccgacacc ccggaagccg agaaaggcgc
     1621 cgccctcgtc atagcggggc gaggcggaca gttcccacca gcgcacatcc ccctccagct
     1681 cgaccggcag gacgatgttg ctgaagcttt cccgccgctt cagatgatcc gccagcgcat
     1741 gcagctcggt cgggaacagg ccgctttccc aggcatttcc agccagcagt tgcaccagca
     1801 gcacgccttc cacttcggcc ggtgtacggc cgagcatttc ggcaaggcgc ggcgacacgc
     1861 cgctcaaccg ccgcgcggga tcggtctgcc acagccagtc ggacgcgcca tgttcatatt
     1921 cgcgcagcag caggctgacg acctcgctct tttcctccag ttgcacgctg gcgctgtgct
     1981 gccgggcgaa ggtccgtgca taaaggaagc agccgaccag cagcgacagc gcatagctgg
     2041 tggcaagggc aagcagcggc gtctggtcgc gcggatcgaa cagcgcgcca agcccgacga
     2101 tgcagggcag caggaagccg gtcgccgcca gcggagtggc ggcatagctg atcgcgccgc
     2161 agaccatgat gcaactgatc agcgtccagt gcgccaccaa ctgcgcggcg ccgtgcccgg
     2221 acgagagcgt catcatgcac gccgcccaga cgaggccgtg aagcaggccg gtgaagccat
     2281 ggaccctgag atcggtcgcg cttgccgccg cgccattgcg cctgcgccgc aggatggcgc
     2341 cgacggccat ggaaaggacc agcgcggcgc tccagaccat cagccccggc acggagccgt
     2401 gatcgccgaa gacctgccac aggaacagca agccgaagag gttcatcgcc tgcctcagca
     2461 gcgcgacatg atcggccgag cgcaattggg cggcaaggac gcgctccgcc gcatcgcccg
     2521 gcacgacggc aagacccatc atcgcccgaa gcgatattcg ctcccgcgaa gcctgttcag
     2581 aagatggccc ttgcccgcgt ctcacccggc cggattaaca gcaagcggtt atcaatccgt
     2641 aacggccgtc aaaagcagat gaaaaaagcg gcccccggcc ggtcggttcg cggcaaaggg
     2701 tcaggcggcg atgtcgtagg gccggatttc gccggtcaga tagaggttgc gcgccttcga
     2761 ccggctgagc ttgcccgagc tggtgcgcgg caaagtgcgc ggcggcacca gttcgaccac
     2821 gcagttcatg ccggtgatcg cccgcacgcg ttcgcggatc tggtcgcgca gccgggtacg
     2881 ctcatcattg tcggaggtgc ggcaatgcac cagcacggcg ggcgcttcct cgccgcccgg
     2941 cgtggtgatg gcaaaggcgg cgatgtcgcc ctgcttgaag ccgggaagct gctccaccgc
     3001 ccattcgatg tcctgcggcc agtgattctt gccgttgatg atgatcatgt ccttggcgcg
     3061 gcccacgata taaagatagc cgtcactcaa atagcccatg tcgcccgtgt ccagccagcc
     3121 gtcgaccatg caggcgtcgg tcgcctcagg atcgcggaaa tagccgacca tgagcgacgg
     3181 cccggtggtc cacaccttgc cgatctgacg ctcgttcagc ttcgctccat cctcgtcccg
     3241 gatttccacg accatgtcgc gcgccggctt gccgcaattg acgatcgagc ggaagcgctg
     3301 cggccggcct tcggtcgcgt cgccgccgga aaggtcggtt tcctccacca gttcgacgat
     3361 gatgccctcg cccggcggca tgatggtgac ggccagcgtg gcctcggcca ggccatagct
     3421 cggcaggaac gccttggggc tgaaccccgc gtccccgaac gcatcgacga agctctgcat
     3481 cacgtccggg cggatcatgt ccgcgccgtt gcccgcgagc ctccaacggg acaggtcgaa
     3541 acgatcctgc gccttggtct ggctcgacat gcggcgcgcg caaatgtcgt agccgaaggt
     3601 cggggaatag ctgatcgagg tgccctcgtt ccggctgatg aggtccagcc acgccagcgg
     3661 ccgccgggcg aaatcctcgg tcttcatata gtcggtcgac acctggttgg cgacgacgga
     3721 caggaagcag ccgaccagac ccatgtcatg ataccagggc agccagctta tgcagcggtc
     3781 gctctcgacc agttccatgc catggctgtg cgccgccaga ttgctgagca gcgcatgatg
     3841 cgtcaccgcc acgccatggg ggaagcgggt cgaaccgctc gaatattgca gataggcgat
     3901 ctcctcgccc ttcgcctgcg gcagatcgca gggcacggct tcccgcgcga tgaaatcctc
     3961 gaaggcgatg ctctcgaccg ccttttgacg gccggattcc cccgccatct cctccagttc
     4021 cttgggaaag aggaacagca tcgggtcgca gctcgacagt tggacgttca actggtcgat
     4081 atagctttcc ttgccgccga agctggtcgg cagcggcagc ggcaccggcc aggcgcccgc
     4141 atagacgatg ccgaagaaca attgcgcgaa atccgggccc gtctccgcca ccagggccac
     4201 gcgatcctcc ggcttcaccc catgggcgat cagccggtgg gcgcaggcga cggcgtcctc
     4261 gcgcagctcc gcaaagggat agggtcgcgc cagattcccc cgcgcgtcgt gaaagttcag
     4321 gccgcgccgc ccggtcgcag catagtccag cgcttcgccc agcgtctcga agtccgagaa
     4381 acggcggggc agatcgtcgg tggttggcgt cggtgccatc atgctttgcg aacccgtcat
     4441 attggtgtca cccaatgtca tgtttgtcat attccggcgc gccgctaaca gctttcaagc
     4501 cgctttgcac cggatagttg cattccagct tgggctttta ccccaaaagg ggcggtaaaa
     4561 ttccggcccg actgtggcat aatcaaggcg caacaggcat gaagcattgc catgaccggc
     4621 aaacgccctc ctgccccgct cgatgaagag gccatgcgcg aacttgcgct gcgctatgtg
     4681 gcgcgcttcg ccaccagccg ggccaaattg ctcgcctatc tgggccgcaa gatcaaggaa
     4741 cgcggctggg gcggcgaaga ccccgccgat ccgcaggcgc tggtcgatcg gctgagcgaa
     4801 ttgcgctatg tcgacgatgc cggctatgcc gtgatgaaaa gcggcgcgct cagccgccgc
     4861 ggttatggcg cccgccgggt cgcggaaacc ctgcgcgccg atggcatagc ggaagccgac
     4921 cgggtggaag cccacgccca gacccaaagg gaaagctggt ccgccgccga ccgcttcgcc
     4981 cggcgcaagc ggatcggccc ctatgcccag gaacgaccgg acctaaagca gcgggaaaaa
     5041 tggattgccg ccttcctgcg cgccggccat gattacgcca ccgcccgccg ctggaccgac
     5101 gccgcgccgg gggaagtgcc ggaagcggat gagtaaccgc tcagcaccct gtttgttaac
     5161 cgccaggctg tgatacctca cccccatgaa gccctttctc ctccttctgc ttgcaattct
     5221 cccggccgcc tgctccccat ccgcccccaa agcagaaaac accgccgcgc ccaccgccac
     5281 cgggcaaacc accctcctcc ccctcaccat ccacaccgcc aaaaccgctc accgcttcac
     5341 cgtcgaactc gcccttaccg aacagcagca ggaacagggc ctgatgttcc gcaagtcgct
     5401 cgcccccgat tccgggatgc tcttccccat gtcaccgccc cgcacggcca gcttctggat
     5461 gaagaacacg ctgatcccgc tcgacatgct gttcatccac accgacggca gcatcgcctt
     5521 cctgaaggcc aacgccgccc cttattcccg cgagccggtc tccgccggca tcccggtcgc
     5581 cgccgtcctc gaactgcgcg gcggcagggc ggcggagctg ggcatcaggg aaggcgaccg
     5641 cgtcacctgg ggcgattgcg accggccgtc ctcgtcaaac cccctcaatt tctgcccccg
     5701 ctgaccagaa ccgccttgcc aagcgccagc cgcaacggct aagcgcttcg cccatgggaa
     5761 tccttggcaa gatcttcacc tggtgggatg gcgcgaccat cggcacctcg ctctacacct
     5821 cccgcaaggg cacgaaggtg ggtgaggacc atcagggcaa tgtctattat gaaggcggca
     5881 ccgaccccaa tggactgacc cggcgctggg tcatctataa tggcgcgaac gacgccagcc
     5941 gcgtgcccgc cgaatggcat ggctggctgc atcattcgat cgagggcgcg ccggagagtt
     6001 tcctgccgcc cccgcgcatc tgggaaaggg acttcacccc caacgccacc ggcacggccc
     6061 aggcctaccg ccccaccggc gcgctggaaa agggcggcct gcgccagaag gcgaccggcg
     6121 attatgaggc gtggagcccc gacgcatcat gatgcggcgc ccggcgggac gtttcctgcc
     6181 gattctcggc tgcaccctgg tactggccgg ttgcggcggc gacgatctgc cgacgcagaa
     6241 ccagggcggt cctgtccgca tcgaggggca gaagatccgc aatggcgacg agtctcccct
     6301 caccggcacg ccgatgaacg agcgggtggc ggtgatcggc ctgctcaaca agcgcaacgg
     6361 catcaccacc gacctgacga tgaagccggg cgaagcgctg cgcgtgggcg atgccattgt
     6421 tcggctgcag gcctgcgaaa ccacggcgcc ctgggaaaat gtgcaggaaa ccggcgcctt
     6481 cgttcagctc gacgtgcgca gcaccgccga caataaatgg cgccgcaact tttccggctg
     6541 gctgttccgg gaacggcccg accgcaatgt cgtgcagcac ccggtctacg acgtctgggt
     6601 caggagctgc acgatgtcat ggccggaaac cggtcccgat acggtgaagc tgggcgacaa
     6661 gggcgaagtg tcggacggcg cgcgggccaa ggcgtccccg gcaagcggcg aaaatgccag
     6721 ctccgcccag acgccggaac cggccgccag cacgccccgc cccgccccca gcgccacgcc
     6781 gtccaacgcg cccgccaatg attgaagata gtcgcgctgg ctgatttcga tcgcacccaa
     6841 tgaccgcaga tgatcggtca tgaactggca gtcgagcagg gtgaaaccgc cgaaacgcat
     6901 gcgggcggtc agccaggcca gcgccacctt cgacgcatcg gcgcgccgcg acaccatgct
     6961 ttccccgaaa aaggcccgcc ccagcgccac gccataaagg ccgccgacca gttcctcccc
     7021 ctcccacacc tcaacagagt gggcgaaacc tatttcatgc agatggcgat aggcacgctc
     7081 gatcggatgg ttgatccagg tggacgggcg gtccggcgcg gcttctgcgc agagccggac
     7141 gatgcctgtg aaatcccgat tggcggtgac ccgaaaccgc tcccgccgga tcgtcttggc
     7201 cagcgaatgg gagatgtgga aaccgtcgag cggcatgatc gcccgtcgct tcggctcgat
     7261 ccagtacacc tcctccgcct cgcgatcgtc ggacatggga aacacgccga tcgcgtaagc
     7321 ctgcaacagc accagcgggt caatcgtcat caaagaaaga cttaacgcga gacagggcag
     7381 cgcgccagtg cgactttcat tccttggacc gccttgcaaa acgggaggcc ccatccgcgg
     7441 tcgatggagc atcaacatga gcggccttaa ggctggggca gaagcaggct ggaatcgcca
     7501 tagctgtaga aacgatagcc gcgatcaatg gcgtgccgat agaccgacag cattttctcc
     7561 gtacccatca aggcgcttac cagcatgaac agggtcgatt tgggcaggtg gaaattggtc
     7621 atcaacccgt cgactgcgcg gaaacgatag cccggcgtga tgaatatccg cgtctcgtcc
     7681 gcgaaaggac ggatgatgcc gtcctccccc gtcgcgcttt ccagcaggcg caggctggtg
     7741 gtaccgaccg cgatcagccg gccgccggcc gcccgtgcgg cgttgaggcg gtccgccgtc
     7801 gcctggtcga tccgccccca ttcggcatgc atccggtgat cgtccgtatc gtcagccttt
     7861 accggcagga aggtgccggc gccgacatgc agcgtcagcg tttcggtccg gacgccggct
     7921 ttttcgaccg ctgccatcaa ttcgggcgtg aagtgcaacg ccgccgtggg ggcggcgacc
     7981 gcgccatcct cccgcgcgaa catggtctgg taatcgctgc ggtcgcgctc gtcggtcggg
     8041 cgcttgctgg cgatataggg gggcagcggc atccggcccg cccgttccag caacagctcg
     8101 accggctcct caccctcgaa gcggagcgtg acgccaccgt cctcgtcgcg cgggccggcc
     8161 acagcggtga cgccattgcc gaagtcgatc cagtcgccat cgcgcacccg cttggcgttg
     8221 cggaggaagg cctgccattg gcgcagaccc agccgcttgt ggagcgtggc gccgaccctg
     8281 gcctggccgc gcatcccctc caattgggcg ggaatgaccc tggtgtcgtt gaaaaccagc
     8341 acgtcgccgg cgcgcagcag gtcgggcaga tcgcgcacga tgcggtcctg gaagggcgcg
     8401 tcgccgggca ccagcagcag ccgggccgcg tcgcgcgggg aagcagggcg aagcgcgatg
     8461 ctttcaggcg ggaggtcgaa atcgaacaga tctacgcgca tggtcgaatg ctctagaaca
     8521 gcatatccaa tgctcctgcg aaggcagaag cccagttcag gcggcgggac tgggctcctg
     8581 ccttcgcagg agcacgcatt cacccggcct gactatttct tcttcggcgc ggccggcttc
     8641 cttgcgggcg cgggcttctt cgccagcggc gcgacgatcg agggcgtggg cggagcaggc
     8701 ggcgtcggca gtgccgtcac cggcggcctg ccgtcgcttt cgatcgaggc ctggaggatg
     8761 atggtcggat cggcgggcgg ttcgccctga tggatggcat cgacatattg catgccctcg
     8821 atcacgcggc cgaacaccgt atatttcttg tcgagctgca tgcgcggcag gaagacgatg
     8881 aagaactggc tgttcgcgct gtcctcgctc tgggcgcggg ccatggagac ggtgccgcgc
     8941 aggtgcggca tcggattgaa ttcggccttc aggtccggca gcgtcgaccc cccggtcccg
     9001 tcccccttgg ggtcgccgcc ctgcgccatg aagccgggaa tgacgcggtg gaatttgagc
     9061 ccgttgtaga agccctggcg cgtcagctcc ttgatccgct cgacatggcc aggcgcgatg
     9121 tcgggacgca actggatgcg cacgcggccg ccgctcgaca ggtccagatc ccagacattt
     9181 tggggatcga caggcaccgt ggccggcggc agcttggaag cgggatcgag gccgagctgc
     9241 ttggcggcct gctccgcgcg cacggccgcc tcctccttct tcatctcctc ggcattgcgc
     9301 ccaccgccgc cctgggccag ggccgcgctg ctcgatgcat agagagcgaa accgatcgcc
     9361 acggtcttga gcgccgacgt gaaccgcatg aatgaagctt tcctcaaatt ttgcccaggt
     9421 gcgaacttgc cctgatagcg ccctcttcgc gattggcaac tgaacgaagg ctgagtggag
     9481 ccttcagccc tgccctttca ggccgatggc ggcgacccgc gcctccactt cctcgcgcac
     9541 ggcggggctg acgaatttgt ggatcggccc gccatagagc gcgatttcct tgaccagacg
     9601 ggaagcgatc ggctgcaacg acacgtccgc catcaggaaa acggtttcga cccggccgtt
     9661 gatctgctgg ttcatccccg ccatctgata ttcatattcg aagtcagcga cggcgcgcag
     9721 gccccggatg atgacgctcg ccccctgcga ttcggcaaag tccatcagca gcgagttgaa
     9781 gcccgtgacg acgatttccg tgtcgatgcc cgcgcattcg cgccgcacca tatccagccg
     9841 ttcatcgtcg gagaacatcg gagatttgga gatgttggtg gtgacgccga tcaccagctt
     9901 atcgaccagc ttcgcgccgc gccggatgat gtccatatga cccaaggtga tcggatcgaa
     9961 tgtcccggga tagaccccca ccctctgctt gctcatgccc ctaacgatcc ctttccacga
    10021 tatagtcggc aatggcgcgc agcaggtcgg cctccggccc gaagccgtgc agatgcgcct
    10081 tcgcctgctc gaccagcagg cggccctgtt cccgcgcccg ctccaccccc agcagggaga
    10141 cgaaggtttc cttccccgcc gccgcgtcct tgcccagcgc cttgccggcg agaacggcgt
    10201 ccccctcgac gtcaagcagg tcgtccgcga tctggaaggc aaggccgatg tcgcgggcat
    10261 agccgtgcag gcgcgtccgc ccctccggcg ggatgcgggc catgatcgcc gccgcatcga
    10321 cgcagaagcc gatcagcgcg ccggtcttca actgctggag ccgcgtgaca gtgggcaggt
    10381 cgaagctggt cttctccgcc tccaggtcca tcatctggcc gcccgccatg ccgctggtgc
    10441 cgctggcgac ggccagcgcc ttcaccagct cgacccggac gaaaggatcg ggatgcgtct
    10501 cctcgtccgc cagcacttcg aaagccagat cgtgcaggca atcgcccgcg aggatcgccg
    10561 acgcctcgtc aaatgccttg tgcacggtcg gcttgccccg gcgaagatcg tcgtcgtcca
    10621 tcgccggaag atcgtcatgc accagcgaat agacatggat gcattccacc gcgacgccaa
    10681 cccgcagcgc cgaatcccgc gagatgttga acaggtcgct ggccgcctgc accagcagcg
    10741 gacgcagccg cttgcctccg cccatggccg catggcgcat cgcttcgtgc aggcgccggc
    10801 gcgggtcgtc gggaaccgcc agcagcgcgt cgaacaggcg gtcgatgtcg gccgccaccg
    10861 ccgcagcgcg gtcggccacc agaccaatcg accgaggcga ggcggagtcg ggtccgctca
    10921 tggccgcctc tcccgcacgc tgcacgctca gtccgaaccg aagggctgag cgccggtcac
    10981 ggcgccgccg gcgtcgatcg tcagcttggc gatgcgcgct tcggccgcct gcagccgttc
    11041 catgcagcgt ttccgcagtt cctcgccctg cgaatagagc gaaatggatt cgtcgagcgg
    11101 cacatccccg ctctccagcc gccggacgat cgattcgagc gcgcgcagcg catcttcgaa
    11161 cgacatctgc gacggatcgc cctcatgggt catgctgtct tgcgccatgt ccctgcattg
    11221 gcgacccccg cccgcccggt caagcccgca tgggccctgg gggccgattc cggccgccat
    11281 tcacgaaaac gtcatgacgt cgcgccactg gctggcggac tcgtggcagt tttgcgttga
    11341 cgcttggcgt ggctagtgca catagaagga ccgctatgaa atatcatctc cccctgatct
    11401 ccgtggcggc gcttgcgctg ctgtccgcct gcaacaagaa tgacgaaccc gaagtggtgg
    11461 gcggccccgc cgatcccatg gccgaaaagc tggccaatgc cgctcccgtc gaactgccgc
    11521 cgatggtgaa ggaaagccat caatatcgtt gcaaggacaa cagcctgatc ttcgtcgact
    11581 tcatgagcga cgacaagacg gtgaacgtgc gcaccgaaaa ggacggcgcc cccacgaagc
    11641 tgaccgccgc cgaggcgggc aagcccttcg aaggcggcgg cttcaaggtc gagggctcgg
    11701 gcaagcagat caccgccacc ctgccgggca agagcgcgct gagctgcaag gcctgatcct
    11761 ttccgttttc ctgcaagtac gggccggccc tccccatgga ggccggcctt tttctttggg
    11821 tttgcgagaa tgtggccaat cgacgccatt cccctcccgc ctgctggagg gggaatggct
    11881 tgaaccgccc aatcatgcac gcccggaccg acgcgctcaa cgcaattccg gctctcccac
    11941 ctcgaccgga tcggggccga agcggttggg cccccgcgtg ccgctcatga tgaagaagat
    12001 cagcaggacg atgctgccga tgatcgggaa gaagacgatc agcagccacc agccgctgcg
    12061 gtcggtatcg tgcaggcggc ggacggaaac cgcgatatgg ggaatgatca tcgccagtgt
    12121 gaacagcccc gtcagcggac caccgcgggt gctgtagccc gcgcccgccc accaggggcc
    12181 gcgctggaac cagtgatcgg tcgtgctgag gcccaatatc ccctcgacca tcgcgacgcc
    12241 gatataacag agcagcagga acaggacgaa catccaatat tcgcgcggcc gcgcccggcc
    12301 ggagaatttg gcgtagcgac gaagcggcaa cagcatccat tccatgggca actccccttt
    12361 ttttcgtccg gccgggaaag ctatcatgtt ttcgcccggg cgcgagcctc agcattgtct
    12421 atcgggcgct cccccgctaa aggcgcgcac atgtccagca ccgcatccca gatcacgccg
    12481 caggtcgtcg cagaccatgg gctttccccg gaagaatatg atcgcgtcct gaacgcgctc
    12541 ggccgggagc cgaatctcac cgaactcggc attttctcgg tgatgtggtc ggagcattgc
    12601 tcttacaaaa gttcgcggat ccatctgaag aagctgccca cggaagggcc gcaggtcatt
    12661 tgcggccccg gtgaaaatgc gggcgtggtg gacatcgggg acggccaggc cgcgatcttc
    12721 aagatggaga gccacaacca tcccagctat atcgaaccct atcagggcgc ggcgacgggc
    12781 gtgggcggca ttttgcgcga cgtcttcacc atgggcgcgc ggccggtggc gaacatgaac
    12841 gcgctgcgct tcgggcggcc cgaccatccg aagatgaagc acctcatcag cggcgtggtg
    12901 catggcattg gcggctacgg caattgcgtc ggcgtgccga ccgtgggcgg cgaggtgaat
    12961 ttccaccccg cctatgacgg caacatcctg gtcaatgcga tgaccgtggg cgtcgcggaa
    13021 acggacaaga tcttctattc cgccgcttcg ggcatcggca atccgatcgt ctatgtgggt
    13081 tcgaagaccg gccgtgacgg catccatggc gcgaccatgg cctcggcgga cttcggcgac
    13141 gacgccgacg ccaagcgccc gacggtgcag gtcggcgatc ccttcaccga aaagctgctg
    13201 atcgaagcct gcctcgaact catggcatcc gacgcgatcg tcgcgatcca ggacatgggc
    13261 gcggcgggcc tcacctcctc ctcggtggaa atggcgtcca agggcggcgt cggcatccag
    13321 ctcaacatgg acgatgtgcc gcagcgcgaa accggcatga ccgcctatga gatgatgctg
    13381 tcggagtcgc aggagcgcat gctcatggtg ctccagccgg gcaaggaagc ctttgccgaa
    13441 gccattttcc gcaagtggga gctggacttc gccgtgatcg gccatgtgac ggataccggc
    13501 cgcatggtgc tggtccacaa gggcgagacg gtgtgcgaca ttccgctggc tccgctggcc
    13561 gacgatgcgc cgctctacga ccgtccggcg atggcgaagg atgaatataa ggcctggtcg
    13621 ggcgtgcagc ccttgggcga gatcagcgag agcgccgaca tcggcgccga tctcgtcagg
    13681 ctgatgggat cgcctgacat cgcctctcgc cgctggatct gggagcagta cgatcatatg
    13741 gtgggcgccg acacggtgca gcgccccggc ggcgacgcgg cggtggtgcg cgtccatggc
    13801 acgcggaagg gcatagcgat cagcaccgac tgcacgccgc gctattgcta tgcggacccc
    13861 tatgagggcg gcaagcaggc gatcgcggaa tgctatcgca acatcagcgc cgtcggcgcg
    13921 acgccgctcg ccgtgaccaa ttgcctgaac ttcgccaatc cgcagcggcc agagatcatg
    13981 gcgcagttca ccggctgcct ggaaggcatg ggggaggctt gccgcgcgct ggatttcccg
    14041 atcgtgtcgg gcaatgtcag cctgtacaat gaatccaagg cgaccggcgg cggatcggcg
    14101 atcctgccca ccccggcgat cggcggcatc ggcctgctcc aggacatcga cgggatggcg
    14161 accgtggcct tcaagaatga gggcgacgcc atctggctga tcggcgggga aggcagccat
    14221 ctcggccagt cgatctggct gcgcgagatt gccggccggg aagcgggcga ggcgccgaag
    14281 gtcgatctgg cggcggagcg tgcccatgcc gaaaccgtcc gggcgctgat cgcggaaggc
    14341 aaggtcaatg cggtgcatga catttccgac ggcggcctgc tggtcgcggt gacggaaatg
    14401 gcgctggccg ggaagatcgg ggcggagctg agcatcgccc ttacgaccgc cagcgccttt
    14461 ggcgaggatc agggccggta catcgtcgcc gccgcccagg gggtggacat tccaggcgcg
    14521 cttcgcatcg gcacgactgg cggcgacaag gtggcgggcg tggcgctggc ggacctgcgc
    14581 agcgcccatg agggcttctt cccggcactg atggacgctg aactttaaag aatagaaatg
    14641 acgtgttcct gcgccgacag gagcacgctg cgctgaatgc gctgaagatg tccattccga
    14701 ggagtcccgc catggccttt accgcgaaga tcctccttct gggctcgggc gaactgggtc
    14761 gtgaattcgt gatctccgcc aagcgcctcg gcgcgcaggt catcgcctgc gacagctatg
    14821 cgggggcgcc tgccatgcag gtggcggacg ggtttgaagt cttctccatg cttgacgccg
    14881 acctgctcgc caaagccatc gaaaagcatc ggcccgactt cgtggtcccc gaaatcgagg
    14941 cgatccgcac cgaggtcctg gccgatttcg aggcgcgcgg cgtgacggtc gtcccttcgg
    15001 cccgcgccac catcatgacc atgaaccgcg accgcattcg cgaagtcgcc gcggtcgaac
    15061 tggggctgcg cacctcccgc tatcgctacg ccgaaacgct ggaggaagtg cgggcggggg
    15121 cggcgcatac cggccttccc tgcgtcatca agccggtcat gtcctcatcc ggcaagggcc
    15181 agagcacggt ccgcacgatt gaagaactgg aagccgcctg ggactatgca gtcgcgaaca
    15241 tgcgcggcga ccgcagccgg gtgatcgtcg aggaattcat cgccttcgac tatgagatca
    15301 cgctgctgac cgtgcgcagc cgtgacggcg tcagcttctg tccgcctatc ggccatcggc
    15361 aggaacgcgg cgactatcag gaaagctggc agcccacgcc catgtccggc ggcgcgctgg
    15421 ccgccgccca ggacatggcg cgcaaggtgg tcgacaatct gggcggctac ggcattttcg
    15481 gcgtggaatt cttcgtgaag ggagaggatg tcatcttctc cgaactctcg ccccggccgc
    15541 acgataccgg catggtgacc ctgatctccc agaactggag cgaattcgat cttcacgccc
    15601 gcgcgatcat gggcctgccg gtgccggaag tgacgctgca tggggccgcg gcttcggcgg
    15661 tgatattggc ggatcgggaa tcggatgact ttcggttcga aggattggcc gaagcgctct
    15721 cgacgcccgg tggggaagtc gatctgcggc tgttcggcaa gccgacgacc cgccactatc
    15781 gccgcatggg cgtcgccctg gcccgcgcga tcgacgcaga ccaggcccgc gccgtcgcgg
    15841 ccgaggctgc atcgaaagtg cggatcatcc atggtcgata gggcggtttc ccgccattag
    15901 gcccctcgcc ttgaaggcga ggtgtcaaca tccgcaactg gcccaatctt gccaatcccg
    15961 catggcatcc caacatgcgt cccgaccccg aagcaaggag cctttcatga ccatcacccg
    16021 ccgcgtcacc gtgcatgaag gccctggcgg tcagttcgag agcatggccg tgttcgacga
    16081 tgccgccgcc gctccgcgtc cggccatcct gcttttcccc aatgttctgg gcaccaagga
    16141 ggccgatttc gcctatgccg aaaaggtcgc ggcgatcggt tacaccgtgc tcgtcgcgga
    16201 tgtgttcggc cagggcaagc ggaccagccg ggccgatccg gacatgggcc gctacatggc
    16261 cgaactcaat gatgaccgca ctttgctgcg ggaccggacg aacgccgccc atgcgctgct
    16321 gaaatcgctc gatgaggcgg acgagagccg gaccgcggcg atcggcttct gcttcggcgg
    16381 caaatgcgtg ctcgaccttg cccgttcagg agcggatatt gcaggcggcg tcagcttcca
    16441 cggcgtctat gatgcgccgc cccttcccca tgcgaagatc accgcgcggc tgctgatctg
    16501 ccacggctgg gacgatccga tcgcgccgcc ggaagccacg gtcgcgctgg cgaaggaact
    16561 gaccgaagcg ggatgcgatt ggcagatcca tgcctatggc cataccgggc acgccttcac
    16621 cgaccatgac gcgaagatgc ccgaaagggg cctggcctat aatcccgaag ccgaccgccg
    16681 cagcttccgc gcgatggccg atttcctggg cgatctcttc ggctgaaccg cggccggccg
    16741 ggttcagatt tcgtcgatca tctccgccag cacgcccagg cagtccttgg cgagttggat
    16801 cgatcgggcc ggcgaccagc cgaaatcggc gtccggcagg tcgtcattat ccttgaacgg
    16861 catttccagc gtcattgcca cggcgccgaa gcgctcggcc aactggttgg tggacatgga
    16921 caagttcgcc ttgcccgccg gcgcggtggg atagcccttc ctcgtctgga aatcgggcgt
    16981 ccgggcggcc agcgtgtcgc gatagcggcg atacaaggcc gacttccgct ccgtgatgga
    17041 ggggatgccc tcgaacccgg ccaggaacac ggccgcaata gcctcgtcgc catgcacgtc
    17101 catggcgaaa tcgaccccga cctcatccat cgccccgcgc accaggaaca cctccggact
    17161 cttctccatc gacggctcat gccattcgcg gttgaggttg atgcccacgg cgttggtccg
    17221 caaatggccg cgacggctgc cgtccggatt catgttcggc acgatgtaga aggtcgcctc
    17281 cctgcgcagc agccgcgcca cggcgtcctc ctcgtcgcag agccgctcca gcgcgccctc
    17341 catccaccat tcggccatgc tttcgcccgg atgctggcgg gcgtagagcc agaccttctt
    17401 cggtccttcc cccagcacca gcaggtcgag cggctgcctg tcgagcgtca gccccagttc
    17461 gcgatgctcc acccccggct gggacgccgc ccaggcgacc agatcatggt gccgttccat
    17521 cgaatagggc gcgaaatagg cgagccacac cgcattgctg tcgggcgaaa gacggatcgt
    17581 cagcgtcccg tcggcatagc cggtgtccgc cagcagccaa ttctcccgat cctcgctata
    17641 gcgcgcctta tagcctggcc agccgtcggg ataggccgac gcgccgcaat tgacgatcgc
    17701 cagttcgact tcccgcccgg ccacgccagc cacgcggaag tggaaccatt ggtagaagtc
    17761 gctctgccgg tccttaacga tctccagctc ggcgcggacg cctgcggacg tggcggaaat
    17821 ggaaagaacg cgaatattgc cgctgtcgaa ggcgcttgtg atcgagatgc tcatctgacg
    17881 gttatagtcc gccccgattc gcccggatag ccccccagca atgccgtcgc cagcttctgc
    17941 gccgccaaac ccggctgcga tgcgggcgtt ccctcccgcg ccccagtctg cgcccggccc
    18001 tcccagatgg tggtcgaatc ggcgcggcgg cgtatctgca cctgcaattc ggtgaagacc
    18061 tgccccttgg gcttgcccga caggttgatg ccgatgccca gccccaggcc ggaatagccg
    18121 ccgctgccca cggcgccgcc cacgccgacg cttaccggct tgccattggc gccatagctt
    18181 tcgggttcgc ggaaggtgcg gcggaaactc accagcgcga catagtcgct cttcgccccc
    18241 tgtgcggccg tggtgaagcc cacgcgctgc aattcctgct cgatcgcggc ggcataggtg
    18301 cggaattcca ggccgacatc ggggttgccg gccatttcct cgacggcgat ggtcccgttg
    18361 cgcgccggat cgtcgatatg gaaccgcgtc acctccaccg gtggaacagc cgtggcgcag
    18421 ccgctgagcc ccagggccag cagggacgga aggacgatct tcttcaacat ggacggattc
    18481 gacatggatg gcactccagg ggatgaacag cctctacacg acaccgcgcc gctaatccct
    18541 taaaagcgtc aagccacgga tttgctgcat gcaggatgaa cggcgcggcg atggagcgaa
    18601 aagcgggcgg ccgcccttga ctttcagccg tcccgcccat aggggctgcg cttcgatttt
    18661 cgatcacgca agattcattc aaaggctggt tccatgaaga tccgcaattc gctcaagtcg
    18721 ctcaagggcc gtcaccggga caaccgcgtg atccgccgtc gcggccgcac ctatgtcatc
    18781 aacaagacca accgccgctt caaggcccgc cagggctgat tcatggcgga tattgccgcc
    18841 gtcgtctttg acgttggcaa tgtcttgtat cactggaccc caagggttct gtacgagcgc
    18901 ctgatcgatg acgatcgggc gctcgatgcg tttctccgcg acgtggtgac gctggactgg
    18961 cacttccagc atgaccaggg ccgccccttc gcggaaacca gcgcagagct gatcgcgcgc
    19021 catcccgaac atgcggcgct gattcgcctc tggggcgaga agttcatcga cagcgtagga
    19081 ccggcagtcg agggcatgcc ggagatcgtc cttgaattgc acgagggcgg cattccgctc
    19141 ttcgccatca ccaatttcag ccatgaattc tgggcgccat tccatgctcg ggagtcggcg
    19201 ctgttcgccc ccttccgcga catcgtggtc tccggcgcgg aaaagctggt gaagcccgac
    19261 cccgcgatct accggctggc gctggagcga ttcggtttga gcgcggaaca ggcgctgttc
    19321 attgatgacc gcgaggaaaa tgtcctggcg gccgaggcgg aaggcatgcg cggccacctg
    19381 ttccgcgatg cggcgacgct gcgccgggaa ctggcagagc tggcgttgct tcgaagccca
    19441 accgtctaag ctggacgtgc ccctgcgaag gcaggagcac gacccttagg agcgatcggc
    19501 attcagccct cgtcccggcc cctcagctca tctccgcgaa tcgcggccac atgcagcaca
    19561 ttggtcgacc ccggcgtccc gaaaggcacg ccggccagca cgacgatctt gccgcccttc
    19621 tcgaccatat cgtggcgcag cgccatgcgg cgggccttgc cgatcatctc ctcgaacgtg
    19681 ccgatgtcct tggtccggac ggcatgcacg ccccaggtca gccccagctt gcgcgccgta
    19741 tcctgccggg gcgtcagcgc caggatcggt gtcatcggcc gctcgcgcgc cacgcggcgc
    19801 acggtgctgc ccgaagaggt gaagcaggtt atcgcgctcg ccccgacgac ggacacgatg
    19861 ctgccggcgc cctccgccag cgcatcggcg gtggtgggat cgggcttcgt ctcggtatag
    19921 tgcagccgcc cgaaatagcc cgggtcgcgc tccacgctat gggcgatgct gtccatcatc
    19981 gtcaccgcct cgaccggcca gtcgcccgcc gccgtttccg ccgacagcat gatcgcgtcg
    20041 gccccgtcat agaccgcggt cgcgacatcg gacacttcgg cgcgggtggg cgtcggcgcc
    20101 ttgatcatgg attccagcat ctgcgtcgcc accacgacgg gccgacccat gcggcgcgcg
    20161 gtcgccacga tctgcttctg cagcggcggc accgcctggg gcggcagttc cacgccaagg
    20221 tcgccccgcg ccaccatcac gccgtcggcc agttcgatga tctcctccag ccgctggaca
    20281 gccgccggct tctcgatctt cgccatcaat gcgccatagc cgcccatcag cttgcgcgcc
    20341 tcggctaggt cctccggccg ctggacgaag ctcagggcga tccagtcgca gccctgctcg
    20401 accgcgaagc tcaggtcgcg ccggtccttt tcggtcagcg ccggcaccgg cacgaccaca
    20461 tcgggcacgt tcacgccctt gcggttggaa agggtaccgc cgacctcgac caccgtgtcg
    20521 atgcgatcct ccgccacctt cttgacccgc agcaccatct tgccgtcgtc cagcaacagc
    20581 cgggtttcgg gcaccagagc cgcatagatc tccggatggg gcaggttgac ccgcgtcgca
    20641 tcgcccggcg caggatcgct gtcgaacacg aaggccgcgc ccgtttccag caccgccagc
    20701 ccgcgatcga aggtcccgac gcgcagcttc ggcccctgaa ggtcgcccag gattgtcgta
    20761 ggacgtccga attccttttc cagcgcccgg atcgtcgcga tgcgcgcggc atgatcctca
    20821 tgcgcgccat ggctcatatt gatgcggaaa gcgtcggccc cggcgacgaa cagcgcccgg
    20881 atcatttccg ggctgtcgct cgcggggcca agggtcgcca a
//
