LOCUS       NZ_BBNO01000006        18605 bp    DNA     linear   CON 19-AUG-2024
DEFINITION  Streptomyces lydicamycinicus strain TP-A0598, whole genome shotgun
            sequence.
ACCESSION   NZ_BBNO01000006
VERSION     NZ_BBNO01000006.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces lydicamycinicus
  ORGANISM  Streptomyces lydicamycinicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Komaki,H., Hosoyama,A., Igarashi,Y. and Tamura,T.
  TITLE     Streptomyces lydicamycinicus sp. nov. and Its Secondary Metabolite
            Biosynthetic Gene Clusters for Polyketide and Nonribosomal Peptide
            Compounds
  JOURNAL   Microorganisms 8 (3), 370 (2020)
   PUBMED   32155704
  REMARK    DOI:10.3390/microorganisms8030370 Publication Status: Online-Only
REFERENCE   2
  AUTHORS   Komaki,H., Ichikawa,N., Hosoyama,A., Fujita,N. and Igarashi,Y.
  TITLE     Draft genome sequence of marine-derived Streptomyces sp. TP-A0598, a
            producer of anti-MRSA antibiotic lydicamycins
  JOURNAL   Stand Genomic Sci 10, 58 (2015)
   PUBMED   26380643
  REMARK    DOI:10.1186/s40793-015-0046-5 Publication Status: Online-Only
REFERENCE   3  (bases 1 to 485565)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: Newbler v. 2.6
            Genome Coverage                   :: 93x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000829715.2-RS_2024_08_19
            Annotation Date                   :: 08/19/2024 02:08:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,323
            CDSs (total)                      :: 7,237
            Genes (coding)                    :: 7,092
            CDSs (with protein)               :: 7,092
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 54 of 145
            Pseudo Genes (incomplete)         :: 123 of 145
            Pseudo Genes (internal stop)      :: 9 of 145
            Pseudo Genes (multiple problems)  :: 39 of 145
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:07:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 466960
            Orig. end                         :: 485565
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBNO01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18605
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..18605
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18605
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[14000:15818](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..15818
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(220..1035)
                     /locus_tag="TU31_RS22470"
                     /old_locus_tag="TPA0598_06_04250"
     CDS             complement(220..1035)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241530.1"
                     /locus_tag="TU31_RS22470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04250"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_042157507.1"
                     /transl_table=11
                     /translation="MAGVARRRLDAELVRRKLARSREHASQLIAAGRVTVGGATATKPA
                     TQVETSAAVVVREDESDPDYVSRGGHKLAGAFAAFVPLGLKIEGRRALDAGASTGGFTD
                     VLLRAGARHVVAVDVGYGQLAWSLQSDERVTVKDRTNVRELTLEQIDSEPVDLVVGDLS
                     FIPLGLVLPALARCAAPDADLVLMVKPQFEVGKERLGSGGVVRSAELRAEAVRAVASRA
                     AELEFGVVGVTASPLPGPSGNVEYFLWLRAGAPALDPADVDRAVAEGPR"
     gene            complement(1043..1456)
                     /locus_tag="TU31_RS40630"
                     /old_locus_tag="TPA0598_06_04260"
     CDS             complement(1043..1456)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984791.1"
                     /locus_tag="TU31_RS40630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04260"
                     /product="hypothetical protein"
                     /protein_id="WP_370682751.1"
                     /transl_table=11
                     /translation="MPAGLVGSDGAAGPDDVAEPRGGAERGGAAESEGADGAGSGAERV
                     EAAEPGGGGRPGAAGEPEGPAEPQPIGVDVTPTGEAAVDARLRRLADADHLPASEHLQV
                     YEDVHRGLRDVLAGLDQHPGPPAPSSTTHDNRS"
     gene            1663..2010
                     /locus_tag="TU31_RS22480"
                     /old_locus_tag="TPA0598_06_04270"
     CDS             1663..2010
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719006.1"
                     /locus_tag="TU31_RS22480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04270"
                     /product="SCP2 sterol-binding domain-containing protein"
                     /protein_id="WP_042157509.1"
                     /transl_table=11
                     /translation="MATLDQCRAALDRLAQNLSSADGSVRQAATFDRSLSCRITDLDVT
                     FLGRLADGTIQEVTNVPGPPPQKADIRLSMAGDDLVALVDGELNFAKAWGSGRVKLEAG
                     LRDLLRLRTLL"
     gene            complement(2405..3397)
                     /locus_tag="TU31_RS22485"
                     /old_locus_tag="TPA0598_06_04290"
     CDS             complement(2405..3397)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138357.1"
                     /locus_tag="TU31_RS22485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04290"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_042157511.1"
                     /transl_table=11
                     /translation="MSRLSAENVTLAYDQRVIAENLSVAIPDHSFTVIVGPNACGKSTL
                     LRALSRMLKPAGGSVLLDGAAISSLPAKKVARTLGLLPQSSIAPDGITVSDLVARGRYP
                     HQGLLRQWSPEDERIVEESMAATGVGELADRYVDELSGGQRQRVWIAMALAQQTPLFLL
                     DEPTTYLDIQHQIEVLDLCAELHEEQGRTLVAVLHDLNHAARYATHLIAMKDGEVIAEG
                     APADIVTAELVEQVFGLGCQIIEDPESGTPLVVPAARKPRKGGARGGRTAEKQSSAGEK
                     QSSAGEKAPSAAEEASAAEKAAGAGEASGVQEPAGAGEASAGVGRGSGR"
     gene            complement(3573..4712)
                     /locus_tag="TU31_RS22490"
                     /old_locus_tag="TPA0598_06_04300"
     CDS             complement(3573..4712)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087966.1"
                     /locus_tag="TU31_RS22490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04300"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_107070729.1"
                     /transl_table=11
                     /translation="MSATVKSGEAVGPGAGKTRATGARRVRAIRTKGGLSVRLDVRATA
                     VGLLLLAVALAAAVALIGSGDYPMTPAEVLAALTGGGDAGQQYIVHDLRLPRVLVGLLV
                     GVAFGVSGAVFQTVSRNPLGSPDVLGFAQGSSVGALAAIVYFQADAFGVAAGAVAGGVG
                     TGLAIFLLAWKRGIHGYRFVLVGIGASAMLYAMVLFLMTKANIVEATRATTWMTGSLNG
                     RDWDQVQPLAAVCAVLVPLLLFFGRPLRMLEMGDDAASALGVRVDRVRVVVLLAAVVLV
                     AAATAAAGPISFVALTAPQLARRLTLPRRLRGGGGSAPMPGPNLVLSGLMGAVLLVAAD
                     WASQRLFGADQLPVGVLTGVLGGGYLLWLLATERKAGRV"
     gene            complement(4709..5713)
                     /locus_tag="TU31_RS22495"
                     /old_locus_tag="TPA0598_06_04310"
     CDS             complement(4709..5713)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087967.1"
                     /locus_tag="TU31_RS22495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04310"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_042157513.1"
                     /transl_table=11
                     /translation="MTPRRRPLLRSAGLVVSVAVLAVIVVLGIAVGAKQIPLDQVWHGV
                     FHYSGSDTDVVIRDVRFPRTLLGLLVGAALGLAGTVMQGLTRNPLADPGVLGINAGASA
                     AVVTAVSFFGVTSLTGYVWFAFAGAAVVNVAVYVLGGTRGATPVRLALAGTALTAVLIG
                     YINAVNLMDTAALDKMRFWTVGSLASATLPTVTAIAPFLAVGGVLALLIARPLNAIALG
                     DDQARALGARLTRTRVLAMLAVTLLCGGATAACGPIVYVGLMVPHAVRAVTGPDMRWIL
                     PYSAVLSPVLLLGADVLGRVVARPGELQVGIVTAVLGGPVFIYLVRRRRMAQL"
     misc_feature    complement(5764..5782)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 30.03"
                     /tool="antismash"
     gene            5821..6849
                     /locus_tag="TU31_RS22500"
                     /old_locus_tag="TPA0598_06_04320"
     CDS             5821..6849
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009715598.1"
                     /locus_tag="TU31_RS22500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04320"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_042157514.1"
                     /transl_table=11
                     /translation="MSTSPNVTLSRRGILAAGGAVGIGALLAACGGGKGSGGANKGAGT
                     GPWSFTDDRKQKVSLKNSPQRIVAFTGTAAALHDFGIDDRIVGVFGPTKLKNGKPDPQA
                     GDLDVDKVTIIGNAYNQFNVEKYASLRPDLLVTNMYEPGALWFVPDDSKDKITPLAKTV
                     AITSARVPLVKIIERYADLAESLGADLRAKKVTDAKARFEHASERLRKAAKAHPVKVLA
                     CSGSPDLFYASNPGINADLMYYKSLGVDLIVPDHLDKGGYFESLSWENADKYKADLLLL
                     DNRTATLQPKDLTAKPSWAKLPAVKAGQITPWSSEPRFSYAGAAPLIESLAKAIEVTKK
                     AN"
     gene            7029..7919
                     /locus_tag="TU31_RS22505"
                     /old_locus_tag="TPA0598_06_04330"
     CDS             7029..7919
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087969.1"
                     /locus_tag="TU31_RS22505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04330"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_042157516.1"
                     /transl_table=11
                     /translation="MTTTAAPATAPFRFFDVHVVRTRRLSPSVVRVTFGGERLAELASG
                     GRDQRFKLFLPQPHQDRPVFHDTGDGWYTAWRAQDPAERPVMRSYTIREQRHEPREFDV
                     DFALHGAGPGASPLAGGPASRWAAHARPGDRLTVLAPAVEDNGGVDFRPPAGTDWILIT
                     GDETALPAIAGILSWLSPGTRAKVWIEIAHEDDRQQLPSFADTDITWLVRNEATAAGHE
                     PVLDALRAAELPEGTPYAWIAGESGTVKAVRRHLVRERGIDRRAVKFTGYWRRGASEEE
                     LLAELTAGAPAPEED"
     gene            complement(7943..8968)
                     /locus_tag="TU31_RS22510"
                     /old_locus_tag="TPA0598_06_04340"
     CDS             complement(7943..8968)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087970.1"
                     /locus_tag="TU31_RS22510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04340"
                     /product="HAD-IIA family hydrolase"
                     /protein_id="WP_042157518.1"
                     /transl_table=11
                     /translation="MNEQVRRRPDGSRQALSEAYDTALLDLDGVVYAGGQAIEHAVESL
                     TRARKGGMHLAYVTNNAARTPQAVADQLSGFGLPTGPDDVITSAQAVARLISEQVPSGS
                     RVLAIGGEGLRVALRERGLVPVGSADDDPAAVVQGYDPSLDWERLAEAAYAVQRGVPWF
                     ASNTDLTIPKERGIAPGNGALVEVVRIAAGGSPQVAGKPQPPMHRETVLRTGARRPLVI
                     GDRLDTDIEGASNGEVDSLLVLTGVTTPAALLAAPPQHRPAYVDEDLRGLLTPQPEVTA
                     ADGGFRCGGWWAEAAGDTLRVAGEGTPVDGLRALCAAAWTAAGDGSYAADTGPALARIG
                     R"
     gene            9140..10405
                     /locus_tag="TU31_RS22515"
                     /old_locus_tag="TPA0598_06_04350"
     CDS             9140..10405
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087971.1"
                     /locus_tag="TU31_RS22515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04350"
                     /product="DUF1015 family protein"
                     /protein_id="WP_042157519.1"
                     /transl_table=11
                     /translation="MTSTDGLRLLPFRGLRYAPERVSSLTAVMSPPYDVVVRPDGVRHL
                     ETADPYNIVRLILPHAADPTTRHRQAADTLHRWRSEGVLTQDTEPALYVYEQRAGEVLQ
                     RGLIGALRLDGPVLPHEGVIPEVVEDRAALMRAAAANFEPLLLSYRGEGTATGAAAVIE
                     RVVEREPLLATTTEDGFAHRLWAVTDPADLTAIDDDLTRRQALIADGHHRWATYQRLYE
                     QRPGATAGSPWASGLVLLVDTARYPLQVRAIHRVLPHLPPAKALADLAGAFRARTLPGE
                     LSAAMEALEETPGTAFVLAGGPDSFHLLDRPDPGLLDRTIRRDRPEAWRQLDATVLHSV
                     LLDEVWHIPDHPSDIGYLHHTEAAVEQAARHGGTAVLMRATSEETVRQLAEHGVTMPRK
                     STSFGPKPATGLVLRTLDGDEN"
     misc_feature    10451..10469
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 33.62"
                     /tool="antismash"
     gene            10558..12087
                     /locus_tag="TU31_RS22520"
                     /old_locus_tag="TPA0598_06_04360"
     CDS             10558..12087
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607800.1"
                     /locus_tag="TU31_RS22520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04360"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_042157521.1"
                     /transl_table=11
                     /translation="MSLLAHSAEDPADHRAYLLNNGTARHYHSAVTESVTRISAKIAGT
                     AQPFTGITVDGLTPTIAGVDLDSPLHDAAAALDELEEVYLRDAVYFHHPRYLAHLNCPV
                     VIPALVGEAVLSAVNSSLDTWDQSAGGTLIERRLIDWTAERIGLGEAADGIFTSGGSQS
                     NLQAMLLARDEACRRELSREGTTDARLTDVLPRLRILTSECSHFSIRKSATLLGMGAEA
                     VIAVPSDDSKRMRTDALAAELARCRRDGLIPMAVVATAGTTDFGSIDPLPEIAGLCAGY
                     GTWMHVDAAYGCGLLVSRRRALLTGIERAASVTVDYHKSFFQPVSSSALLVRDRATLRH
                     VTYHADYLNPRRMVEQRIPNQVDKSIQTTRRFDALKLWLTLRIMGAQAVGELFDEVIDR
                     AADAWKLLHDDPRFEVVVEPRLSTLVFRYVPSTDRDPELSDRVNLHAREALFASGAAIV
                     AGTVVDGRHYLKFTLLNPETTLEDIATVLDLIAEHAGSFLAEQPRPALSAR"
     gene            12122..13438
                     /locus_tag="TU31_RS22525"
                     /old_locus_tag="TPA0598_06_04370"
     CDS             12122..13438
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087973.1"
                     /locus_tag="TU31_RS22525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04370"
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="WP_042157523.1"
                     /transl_table=11
                     /translation="MSAPYDFIAIGLGPFNLGLACLTEPIDGLDGLFLDDKASFDWHPG
                     MMLDSSHLQVPFLADLVTLADPSSPFSFLNYLKESGRLYSFYIRENFYPLRAEFNDYCR
                     WAAGKLDSVRFAHRVTTVEYDAREELYTVHAEQPTGERHTFRARRLVLGTGTPPYVPDA
                     CRDLGGDLLHNAGYLDAKAALQAKDSITLIGSGQSAAEIYYDLLQDIDSHGYHLTWATR
                     SPRFFPLEYTKLTLEMTSPEYVDYFHALPPATRDRLNATQKHLYKGIDSELINDIFDLL
                     YQKNLAGPVPTRLLTNTALHQASYDETSGTYTLGLRQEEQGTDFALDTQGLILATGYRY
                     RVPDFLSPVRDRIVWDDAGRYDVARNYSIDTTGQGIFVQNAELHTHGFVTPDLGMAAYR
                     NACIIRELLGREYYPVEKAIAFQEFAAPAGPHHPMELPA"
     gene            13435..14004
                     /locus_tag="TU31_RS22530"
                     /old_locus_tag="TPA0598_06_04380"
     CDS             13435..14004
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087974.1"
                     /locus_tag="TU31_RS22530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04380"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_042157525.1"
                     /transl_table=11
                     /translation="MTTPLFTRTDAALGEFSLRPVDPYGDAELLHRWVTHPKAAFWLMQ
                     DCDLAAVEKEFARISADPFHDAFLGLHNGTPAFLMERYDPAHRELVGIHAAEPGDVGMH
                     FLSAPTDTPVHGFTLAVITTVMEMLFADPDARRVVVEPDARNTAVHALNKAVGFEVLRT
                     VSLPSKDAYLSTCTRDQFLATRGDHR"
     gene            14001..15818
                     /locus_tag="TU31_RS22535"
                     /old_locus_tag="TPA0598_06_04390"
     CDS             14001..15818
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087975.1"
                     /locus_tag="TU31_RS22535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04390"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_042157527.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.8e-79, bitscore:
                     260.9, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPSDGTPHLSARDAVAHLTPGLWARANRLLIRKGLAEFAHERL
                     LTPRRLPQDGHYAVRSDDGATEYRFAARRRALDHWQIDADSITRHRDHDELPLDALAFF
                     LELRDSLGLGEAILPVYLEEISSTLSGTAYKLAAGRPSAAELAKADFQAVETGMTEGHP
                     CFVANNGRLGFGIHEYHAYAPETAAPLRLIWLAAHRDHATFTAGAGLDYDALIRDELPD
                     TTRARFTATLTTLGLDPADYYFFPTHPWQWWNKLSVTFAAEVARQRLVCLGPGDDDYLA
                     QQSIRTFFNTTSPTKHYVKTALSVLNMGFMRGLSASYMEATPAINDWLARLIDADDTFR
                     AARFSIIRERAALGYHHRQYEAATAKGSPYRKMLAALWRESPVPTIEPGQRLATMASLL
                     HTDEDGGSLAAALIEESGLEPAVWLRRYLDAYLTPVLHAFYAYDLVFMPHGENAILVIE
                     DGAVARVIFKDIAEEIAVMDPDAVLPPAVERIRADVPEDKKLLSVFTDVFDCFFRFLSS
                     ILDDHGILDEDTFWRTVAACVTDYQAATPQLADKFERYDLFTDEFALSCLNRLQLRNNQ
                     EMVDLQDPAGALQLIGTLRNPLAPYAPAS"
     gene            complement(15905..16669)
                     /locus_tag="TU31_RS39390"
                     /old_locus_tag="TPA0598_06_04400"
     CDS             complement(15905..16669)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004952736.1"
                     /locus_tag="TU31_RS39390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_06_04400"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_370682752.1"
                     /transl_table=11
                     /translation="MKRLPIPEDVTGDEIDKDVRQELLSLPKTLADDVAKNLVMVAKLL
                     DEDPEQAYGYSRVALRLASRVAAVREAAGFAAYAVGKYSEALAEFRAARRMTGSVELWP
                     VMADCERGLGRPEKAMAMAGEPEVQKLDKAGQVEMRLVAAGARRDMGQADAAVVTLQSP
                     ELASSAVHPWTARLRYAYADALLAVGREDEARDWFARALEADQGGTTDASDRLAELDGV
                     EFTDALEEADEADEADAAEDDGAQGEAGSAKD"
     gene            complement(16597..17730)
                     /locus_tag="TU31_RS39395"
                     /old_locus_tag="TPA0598_06_04410"
     CDS             complement(16597..17730)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TU31_RS39395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TPA0598_06_04410"
                     /product="hypothetical protein"
                     /protein_id="WP_219819213.1"
                     /transl_table=11
                     /translation="MMTAPRVATVVDTAVATGGTTAVGTVAASVGMTAGRGGMTVRTAA
                     TGGMIAVGSVVMTGRPVAIAVVTAVATVAMTAVETAAVSVGTTVPMVVTVGDSAVMTGR
                     PVATVVASAVTTAVTTVVMTAVGSVVMTGRPVATVVVTAVVTVAMTVVGTAAASVVMTV
                     VAIGVGSVVMTGRRVATVVGSVVATGGTTAAGTVVASVGMTVGRGGMMSVVAGSGATTA
                     VGTVPASGGTTAVGTVPASGGTTVVDTAVVTGAMIAAGTVVASGGTTGRRVATVGGSVA
                     VTGAMTAVATVGTTAVVTGVGSVGTTVGRGAMTVGGSGGMTSVGGVGRTAVAGGGMTAG
                     TIAVMTGGTGIGSRSSGCRFRRMSPGTRSTRMCVRSC"
     misc_feature    complement(17842..17856)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.62"
                     /tool="antismash"
     misc_feature    complement(17983..17996)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.81"
                     /tool="antismash"
     rRNA            complement(17992..18108)
                     /db_xref="RFAM:RF00001"
                     /gene="rrf"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="TU31_RS22550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="TPA0598_06_r0010"
                     /product="5S ribosomal RNA"
     gene            complement(17992..18108)
                     /gene="rrf"
                     /locus_tag="TU31_RS22550"
                     /old_locus_tag="TPA0598_06_r0010"
     misc_feature    18137..18150
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.24"
                     /tool="antismash"
     misc_feature    18138..18151
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.58"
                     /tool="antismash"
     misc_feature    complement(18139..18152)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.96"
                     /tool="antismash"
     misc_feature    complement(18140..18153)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    complement(18141..18154)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.83"
                     /tool="antismash"
     rRNA            complement(18223..>18605)
                     /db_xref="RFAM:RF02541"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="TU31_RS22555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="23S ribosomal RNA"
     gene            complement(18223..>18605)
                     /locus_tag="TU31_RS22555"
ORIGIN
        1 atacctcgga gtcgacgcgc tggaccgacg acggcagcgg cagatccgcc gcctcctccg
       61 ccagcacacg caccccgatg ccgctgcgca gcagcccctg gacaacgagt tcggcactgc
      121 ggatggccgc ggggcggccc gtgtgtgcga gcaggaacac cgtccgcccg gctccggtgt
      181 tctcgtgtgc tgcgctgcct tcaactgcat gggtagtggt caacgaggcc cctccgccac
      241 tgcacggtcg acgtccgccg ggtcgagtgc aggcgccccg gcgcgcagcc acagaaagta
      301 ctcgacattc ccggaaggtc caggcagtgg gctcgcagtt acgccaacta cgccaaattc
      361 cagttcggcg gcccggctcg cgaccgcgcg gacggcctcg gcccgcagct ccgcgctgcg
      421 caccaccccg ccgctgccca gccgctcctt gccgacctcg aactgcggct tgaccatcag
      481 caccagatcc gcgtcgggcg ccgcacagcg ggccagcgcg ggcagtacga gccccagcgg
      541 gatgaaggag agatcaccga cgacgaggtc gacgggctcc gagtcgatct gctccagggt
      601 caattcgcgt acgttggtgc ggtccttcac ggtgacccgt tcgtcgctct ggagcgacca
      661 ggcgagctgt ccgtatccga cgtcgacggc gacgacatga cgtgcgccgg cccgcagcag
      721 gacatcggtg aagccaccgg tcgaggcacc cgcgtccagc gcccggcggc cctcgatctt
      781 caggccgagg gggacgaagg cggcgaacgc cccggcgagc ttgtgcccgc cgcgcgagac
      841 atagtcgggg tcgctctcgt cctcgcggac gaccacggcc gcgctggtct ccacctgggt
      901 ggccggtttg gtcgcggtcg ccccgccgac ggtcacccgg cccgcggcga tcagctggct
      961 cgcgtgctcg cgggaacggg ccagcttgcg gcgcaccagc tccgcatcga gtcggcgtcg
     1021 tgccactcct gccacctgtg gttcagctcc tgttgtcgtg cgtcgtcgag gaaggggcgg
     1081 gcggcccggg gtgctggtcg agaccggcca gcacatcgcg cagcccacga tgcacatcct
     1141 cgtacacctg gaggtgttcg ctcgcgggga ggtggtcggc gtcggcgagg cgccgcagcc
     1201 gggcatcgac cgcggcctca ccggtcggtg tcacgtccac cccgatcggc tgcggctcag
     1261 cgggcccctc cggctcgccc gcggcgcccg gccggccccc tccgcccggc tcagcggcct
     1321 cgacccgctc ggcaccgctg cccgccccat cggcaccctc cgactcagcg gcaccgcccc
     1381 gctcggcgcc gccgcgcggc tcagcgacat cgtccggccc tgccgcgccg tccgacccga
     1441 cgagaccggc cggcactcca cccgcggtgc tcacggctcc gctgccctcg cgctgccagg
     1501 gctccttcgg ttccacgggc tctgtggggt cccctggcgc ggcttgcgcg ggcgcctccg
     1561 gctccgggcc ggacgtcggc tcttccatgc ccccgacgct acctcggcga agccggtcga
     1621 ggaggaacga gccgtccccg acctggcgta tcgtcgatca cgatggcaac cctcgaccag
     1681 tgccgcgccg ctctcgaccg gctggcccag aacctgtcct cggccgacgg cagcgtccgc
     1741 caggccgcca cgttcgaccg ctcactcagc tgccgcatca cggacctcga tgtgaccttc
     1801 ctcgggcggc tggccgacgg caccatccag gaggtgacca acgtcccggg cccgcccccg
     1861 caaaaggccg acatcaggct gtccatggcg ggcgacgacc tggtggccct ggtggacgga
     1921 gagctgaact tcgccaaggc ctggggcagc ggccgcgtca agctggaggc cggcctacgc
     1981 gacctgctcc gcctcaggac actgctgtaa cagcagcccg tcccgctgta ccagcagccc
     2041 atcccgtcgc gcctggccac gcgcagcccg ctcgtcacac gcgctcatca caggcgcagc
     2101 cccgctcgtc acacccggtc gcgccccgcc ggccgccgcc cggggcgtcg cggccgcccg
     2161 gccgctgccc cgggccgtcg cacactcgcc ggccacagct ccgctcggcg cgctcccggt
     2221 cagccgcaac cccgctcgtc gcacccacgt gcgccggagc cggaccaccg cccgtcacgc
     2281 cccctcagcc gtgtcccccg agcgccccac cgaccacgcc ctgacgcatc acgccccgcg
     2341 cggccccgcg cggccaagcc gaccggccat ggccccacga cgcgccctca cccccacccc
     2401 tcccctaccg accgctcccc cgcccaaccc ccgccgaagc ctccccagcc cccgcaggct
     2461 cctgcacccc cgaagcctcc cccgcccccg cagccttctc cgctgccgaa gcctcctccg
     2521 ctgccgaagg cgccttctcg cccgcggacg actgcttctc ccccgcggac gactgcttct
     2581 ccgccgtccg acccccgcgc gcacccccct tacgcggctt gcgtgccgcc ggcaccacca
     2641 acggagtgcc gctctccggg tcctcgatga tctggcagcc gaggccgaag acctgctcca
     2701 ccagttccgc cgtgacgatg tcggccgggg cgccctcggc gatgacctcg ccgtccttca
     2761 tggcgatgag gtgtgtcgcg taacgggccg cgtgattgag gtcgtgcagc accgcgacca
     2821 gcgtgcgtcc ctgctcctcg tggagctcgg cgcacaggtc cagcacctcg atctgatgct
     2881 ggatgtccag atacgtcgtc ggctcgtcca gcaggaacag cggggtctgc tgggcgagcg
     2941 ccatcgcgat ccacacccgc tgccgctgcc cgccggacag ctcgtcgaca tagcggtcgg
     3001 ccagctcgcc gacgccggtg gccgccatcg actcctcgac gatccgctcg tcctcgggcg
     3061 accactgccg cagcagcccc tggtgcggat agcggccgcg ggccaccagg tccgacacgg
     3121 tgatcccgtc cggggcgatc gaggactgcg gcagcagccc gagcgtcctg gcgaccttct
     3181 tggccggcag cgaggagatc gccgcgccgt ccagcaggac cgatccgccg gccggtttga
     3241 gcatccgcga gagcgcgcgc agcagcgtgg acttaccgca ggcgttgggg ccgacgatga
     3301 ccgtgaagga gtggtcgggg atggcgaccg agaggttctc ggcgatgacc cgctggtcgt
     3361 aggcgagggt gacgttctcg gccgagagac ggctcacttc ggaactcctg gggttgtcgt
     3421 gtcactgctg tgggccggcc cggtgccggc cgcaccgtcg ccggccaggg gccgcaccgt
     3481 cgcccggccc gcgcggggtt gtggcccggc ggcagccgcg ccgccctccg gcacccgcct
     3541 cctggccggt ccttccaccg gcgcccggcc gctcacaccc gtcccgcctt gcgttccgtg
     3601 gccagcagcc acagcagata gccgccgccg aggacaccgg tgagcacccc caccggcagc
     3661 tggtcggcgc cgaagagccg ctgggacgcc cagtcggcgg cgaccagcag cacggcaccc
     3721 atgaggccgg agagcaccag attgggaccg ggcatcgggg cgctgcctcc cccgcccctg
     3781 agccggcgcg gaagggtcag ccggcgggcc agctggggtg cggtgagcgc cacgaaggag
     3841 atcggcccgg ccgccgcggt ggcggccgcg acgagcacca ccgccgccag cagcacgacg
     3901 acacggaccc ggtcgacccg tacgccgagc gcggacgcgg cgtcatcgcc catctccagc
     3961 atgcgcagcg gccgtccgaa gaacagcagc agcggcacga ggacggcgca gaccgcggcc
     4021 agcggctgga cctggtccca gtcacggccg ttgagggaac cggtcatcca ggtggtggcc
     4081 cgggtcgcct cgacgatgtt cgccttggtc atgaggaaga gcaccatcgc gtagagcatg
     4141 gcgctcgctc cgataccgac gagcacgaag cggtagccgt ggatgccgcg cttccaggcg
     4201 agcaggaaga tggcgagccc ggtgcccacc ccgccggcca ccgctccggc cgcgaccccg
     4261 aaggcatcgg cctggaagta gacgatggcg gccagggcac cgacggacga gccctgggcg
     4321 aagcccagga cgtccgggct gcccagcggg ttgcgggaga cggtctggaa gaccgccccg
     4381 gagaccccga acgccacacc gaccaacagc cccaccagca cccgcggcag ccgcaggtcg
     4441 tgcacgatgt actgctggcc ggcgtccccg ccgccggtca gggcggcgag cacctcggcc
     4501 ggggtcatcg ggtagtcgcc ggagccgatc agggcgacgg cggcggccag tgcgacggcc
     4561 agcagcagca gtccgacggc cgtggcgcgt acgtccaggc gcaccgacag gccgcccttg
     4621 gtgcgtatcg ccctcacccg ccgggccccc gtcgcccggg tcttcccggc cccgggcccc
     4681 accgcctcac cggacttcac ggtcgcgctc acagctgggc catcctccga cgtcgtacga
     4741 gatagatgaa gaccggtccg ccgaggacgg ccgtgacgat gccgacctgg agttcaccgg
     4801 gccgggccac gacccggccg aggacatccg cgccgagcag caggaccggt gagagcaccg
     4861 cggagtacgg caggatccag cgcatatcgg gcccggtgac ggcccgtacg gcatgcggaa
     4921 ccatcaggcc cacatagacg atcgggccgc aggcggcggt cgccccgccg cacagcaggg
     4981 tgacggcgag catcgccagc acccgggtgc gggtcagccg ggcgcccagc gcccgcgcct
     5041 ggtcgtcgcc gagcgcgatg gcgttcagcg gccgggcgat cagcagcgcg aggacgcccc
     5101 ccaccgccag gaacggcgcg atcgcggtga ccgtcggcag agtggccgag gccagcgaac
     5161 ccaccgtcca gaagcgcatc ttgtccagcg ccgcggtgtc catcagattg acggcgttga
     5221 tgtagccgat gaggacggcg gtcagcgcgg tgccggccag ggcgagccgt acgggcgtgg
     5281 caccccgggt gccgccgaga acgtacaccg cgacattgac caccgcggcg ccggcgaacg
     5341 cgaaccacac atagccggtc agcgaggtga cgccgaagaa gctgacggcg gtgacgaccg
     5401 cggccgaggc accggcgttg atgccgagaa ctccggggtc cgccagggga tttcgggtca
     5461 gcccctgcat gaccgtgccg gccaggccga gcgcggcgcc gacgagcagg ccgagcaggg
     5521 tgcgcgggaa gcggacatcg cggatgacga cgtcggtgtc ggagccggag tagtggaaca
     5581 ccccgtgcca cacctggtcg agggggatct gcttggcgcc gacggcgatg ccgaggacga
     5641 cgatgacggc caatacggcc accgagacca ccagccccgc ggagcgcagg agggggcgcc
     5701 gacgaggagt cacggggtcc ggagccgttg ccgcttcggg gggactgtca accaacacga
     5761 tggttaggtt agcctaccct cacattcgac tcgcagtccc tcccagagag aagtgcgccc
     5821 atgagcacct ccccaaacgt cactctgtcc cgtcgcggca tcctggccgc ggggggcgcc
     5881 gtcggtatcg gcgccctgct ggccgcatgc ggcgggggca agggctcggg gggtgccaac
     5941 aagggcgccg gcaccggccc gtggtccttc accgacgacc gcaagcagaa ggtctcgctg
     6001 aagaactccc cgcagcgcat cgtcgccttc accggcaccg cggccgcgct gcacgacttc
     6061 gggatcgacg accggatcgt cggtgtcttc ggccccacca agctcaagaa cggcaagccc
     6121 gatccgcagg ccggcgacct ggatgtcgac aaggtcacca tcatcggcaa cgcctacaac
     6181 cagttcaacg tcgagaagta cgcgtccctg cgccccgatc tgctggtcac gaacatgtac
     6241 gagccgggcg ccctgtggtt cgtaccggac gacagcaagg acaagatcac cccgctggcg
     6301 aagaccgtcg ccatcacctc ggcccgggtc ccgctcgtca agatcatcga acgctacgcc
     6361 gacctggccg agtcactcgg cgccgacctc cgggcgaaga aggtcaccga cgccaaggcc
     6421 cgcttcgagc acgcctccga gcggctgcgc aaggccgcca aggcccaccc ggtcaaggtg
     6481 ctcgcctgct ccggcagccc ggacctcttc tacgcctcca accccggcat caacgccgac
     6541 ctcatgtact acaagtccct cggtgtcgat ctgatcgtcc ccgaccacct ggacaagggc
     6601 ggctacttcg agagcctgag ctgggagaac gccgacaagt acaaggcgga tctgctcctg
     6661 ctggacaacc ggaccgccac cctccagccc aaggacctga cggccaagcc ctcctgggcc
     6721 aagctgcccg ccgtcaaggc cggccagatc accccgtggt cgagcgagcc gcgcttctcc
     6781 tacgcgggcg ccgccccgct catcgagtcg ctcgccaagg ccatcgaggt caccaagaag
     6841 gccaactgac gtacggccgc ggtggatcgc cggtccccgg ccgcagcacc tcccggccgc
     6901 cacggtccac cgcggcaccc acgcacctca gcgcctcggc gtctccgcgc ccgacgccac
     6961 cgcaccaccc gagagccacc gcaccaccac accgcacagt ccgcgccccg tcccgggagg
     7021 tcccccacat gaccacgacc gccgcacccg ccaccgcacc gttccgcttc ttcgacgtgc
     7081 atgtcgtacg gacccgacgg ctgagcccct ccgtggtgcg ggtcaccttc ggcggtgaac
     7141 ggctggccga actggcctcc ggcggtcgtg accagcgctt caagctcttc ctcccgcagc
     7201 cccaccagga ccggccggtc ttccacgaca ccggcgacgg ctggtacacc gcctggcggg
     7261 cgcaggaccc ggccgagcgg ccggtgatgc gctcgtacac catccgcgaa cagcgccatg
     7321 aaccacggga gttcgatgtc gacttcgcgc tgcacggtgc cgggccggga gcctcgccgc
     7381 tggccggcgg ccccgcctcc cgctgggccg cccacgcccg gcccggcgac cggctgaccg
     7441 tcctcgcccc ggccgtggag gacaacggcg gtgtcgactt ccggccgccg gccggcaccg
     7501 actggatcct gatcaccggc gacgagacgg cactgcccgc gatcgccggc atcctgtcct
     7561 ggctctcccc cggcacccgc gccaaggtct ggatcgagat cgcgcacgag gacgaccggc
     7621 agcagctgcc gtccttcgcc gacaccgaca tcacctggct cgtccgtaac gaggcgaccg
     7681 ccgcagggca cgagccggtg ctcgacgccc tgcgcgccgc cgagcttccc gagggcaccc
     7741 cgtacgcctg gatcgccggc gagtccggca ccgtcaaggc ggtgcgcagg catctcgtcc
     7801 gcgagcgcgg catcgaccgc agggccgtca agttcaccgg ctactggcgc cgtggcgcct
     7861 ccgaggaaga gctgctcgcg gagctgacgg ccggtgcccc ggcacccgag gaggactgat
     7921 ccccgcgcgc cgggacaccg tctcacctgc cgatccgcgc cagcgccggc cccgtgtccg
     7981 ccgcgtaact gccgtccccc gccgccgtcc aggccgccgc gcacagcgcc cgcagcccgt
     8041 cgaccggtgt gccctcgccg gccacccgca gggtgtcgcc ggccgcctcg gcccaccagc
     8101 caccgcaccg gaaaccgccg tcggccgcgg tcacctccgg ctgcggggtc agcagcccgc
     8161 gcagatcctc gtccacatag gcggggcggt gctgcggcgg ggccgccagc agcgcggccg
     8221 gtgtggtgac gccggtgagc accagcagcg agtcgacctc accgttgctg gccccctcga
     8281 tgtcggtgtc gagccggtcg ccgatcacca gcggccgccg cgccccggtc cgcagcaccg
     8341 tctcccggtg catcggcggc tgcggcttgc ccgccacctg cgggctgccg cccgcggcga
     8401 tccggaccac ctccaccaac gcaccgttgc cgggcgcgat cccgcgctcc ttggggatcg
     8461 tcagatccgt gttggacgcg aaccaaggca ccccgcgctg caccgcgtac gcggcctccg
     8521 ccagccgctc ccagtccagc gaggggtcgt agccctgcac cacggccgcc gggtcgtcgt
     8581 ccgcggagcc gaccgggacg agaccgcgct cgcgcagcgc cacccgcagc ccctcgccgc
     8641 cgatggccag cacccgcgag cccgacggca cctgctcgga gatcagccgc gccaccgcct
     8701 gcgccgaggt gatcacatcg tccggaccgg tcggcagacc aaaaccggac agctggtcgg
     8761 cgacggcctg cggggtccgg gcggcgttgt tggtcacata ggcgaggtgc attccgccct
     8821 tgcgggcgcg ggtcagcgac tccacggcgt gctcgatggc ctgtccgccg gcgtagacca
     8881 ccccgtccag atccagcagc gcggtgtcat atgcctcgct cagcgcctgc cgggacccgt
     8941 cgggccgcct gcgaacctgc tcgttcatgc cgtctcgctc ctcgctccac acatcgcgcc
     9001 ggggatccgc cgcccccggg ggcgcactca ccgcaccgtg gggacgctcg ccctccactt
     9061 cgcgcatacc gatatttcca gccacccacg ggctgtcccc cgatcttccc tcatccgtcc
     9121 ggcggcatag cattcttcaa tgaccagtac cgacggcctc cgcctcctcc cgttccgcgg
     9181 gctgcgttac gccccggagc gggtcagcag cctgaccgct gtgatgtccc cgccgtacga
     9241 cgtggtggtc cggccggacg gcgtgcgcca tttggagacc gccgatccgt acaacatcgt
     9301 ccggctgatc ctcccgcacg ccgcggaccc caccacccgc caccgccagg ccgccgacac
     9361 cctgcaccgc tggcgcagcg agggcgtgct gacgcaggac accgagcccg cgctgtacgt
     9421 ctacgagcag cgcgccggtg aggtgctcca gcgcgggctg atcggggcgc tgcgcctgga
     9481 cggtccggtg ctgccgcacg agggcgtcat ccccgaggtg gtcgaggacc gggccgccct
     9541 gatgcgggcg gcggccgcga acttcgaacc gctgctgctc tcctaccgcg gtgagggcac
     9601 cgcgaccggc gccgccgcgg tcatcgagcg cgtggtggag cgggagccct tgctcgccac
     9661 cactacggag gacggcttcg cgcaccgcct gtgggcggtc accgacccgg ccgacctcac
     9721 cgccatcgac gacgacctca cccgccggca ggccctgatc gccgacggcc accaccgctg
     9781 ggcgacctac cagcggctgt acgagcagcg gcccggcgcc accgccggct caccctgggc
     9841 ctccggtctg gtgctgctgg tggacaccgc ccgttacccg ctccaggtcc gcgcgatcca
     9901 ccgggtactg ccgcatctgc cgcccgccaa ggcgctggcg gacctggccg gcgccttccg
     9961 tgcccgtacc ctccccggcg agctgtccgc cgccatggag gccctggagg agacgcccgg
    10021 caccgccttc gtgctcgccg gcggtccgga ctccttccat ctcctggacc gtcccgaccc
    10081 cggtctgctg gaccggacga tccgccggga ccggcccgag gcctggcggc agctggacgc
    10141 caccgtgctg cactccgtcc tgctggacga ggtctggcac attcctgacc acccgtcgga
    10201 catcggctat ctgcatcaca ccgaagccgc cgtcgagcag gccgcccggc acggcgggac
    10261 ggccgtgctg atgcgtgcca cctccgagga gacggtccgt cagctcgccg agcacggggt
    10321 gacgatgccg cggaagtcca cctccttcgg ccccaagccc gccacgggcc tggtcctgcg
    10381 caccctggac ggcgacgaga actgaccttc agggcgccgt cacggtccct caaccccgcc
    10441 ccgcgactag ttaggttagg ctaacctcac tacgtcgccg ggcggggtct ccctgcccct
    10501 gcgcacaccc cgtcctgcgc aggacgtggt caactccgca ccagggagga caccttcatg
    10561 agtctcctcg cgcattccgc cgaggacccg gccgaccacc gggcgtatct gctcaacaac
    10621 ggcaccgccc gccactacca cagcgcggtc accgagagcg tcacgcggat cagcgccaaa
    10681 atcgccggca ccgcccagcc gttcaccggc atcaccgtcg acggcctcac ccccaccatc
    10741 gccggcgtcg acctcgacag cccgctgcac gacgcggccg ccgcgctcga cgaactcgaa
    10801 gaggtctacc tccgcgacgc cgtctacttc caccacccgc gctacctcgc gcacctcaac
    10861 tgccccgtgg tgatccccgc cctcgtcggc gaggccgtgc tctccgccgt caactcctcc
    10921 ctggacacct gggaccagag cgcgggcggc acgctcatcg agcgccggct gatcgactgg
    10981 acggccgagc ggatcggcct gggcgaggcg gccgacggca tcttcaccag cggcggcagc
    11041 cagtccaacc tccaggccat gctgctcgcc cgcgacgagg cctgccgccg ggaactgagc
    11101 cgcgagggta cgacggatgc ccggctcacc gacgtactgc cccggctgcg catcctcacc
    11161 tccgaatgca gccacttcag catccgcaag tcggccaccc tgctcggcat gggcgccgaa
    11221 gccgtcatcg ccgtccccag cgacgacagc aagcgcatgc gcaccgacgc gctcgccgcc
    11281 gaactggccc gctgccggcg tgacggcctg atacccatgg ccgtcgttgc caccgccggc
    11341 accaccgact tcggctccat cgacccgctt cccgagatcg ccggcctgtg cgccgggtac
    11401 ggcacctgga tgcatgtcga cgccgcctac ggctgcggac tgctggtctc ccgccgccgc
    11461 gccctgctga ccggcatcga acgcgccgcc tcggtgaccg tggactacca caagtccttc
    11521 ttccagccgg tcagttcgag cgccctcctg gtccgcgatc gcgccaccct gcgacatgtc
    11581 acctaccacg cggactatct caacccccgc cgcatggtgg agcagcgcat ccccaaccag
    11641 gtcgacaagt cgatccagac cacccgccgc ttcgacgccc tcaagctctg gctcaccctg
    11701 cgcatcatgg gcgcccaggc cgtcggcgaa ctcttcgacg aggtcatcga ccgggccgcg
    11761 gacgcctgga aactgctgca cgacgacccc cgcttcgagg tcgtcgtcga gccccggctg
    11821 agcaccctgg tcttccgcta cgtcccctcc accgaccggg accccgagct cagcgaccgg
    11881 gtcaatctgc acgccaggga ggcgctgttc gcctccggcg cggcgatcgt cgcgggcacc
    11941 gtcgtcgacg gccgccacta cctcaagttc accctgctca acccggagac cacgctcgag
    12001 gacatcgcca ccgtcctcga cctgatcgcc gagcacgccg gcagcttcct cgccgagcag
    12061 ccccggccgg ccctcagcgc gcgctgaccc tccccgccaa cagtccccat cggagacccg
    12121 tgtgtccgcc ccttatgact tcatcgccat cggcctcggc ccgttcaacc tgggcctggc
    12181 ctgcctgacc gagccgatcg acggactcga cggcctgttc ctggacgaca aggcgtcctt
    12241 cgactggcac cccggcatga tgctggacag cagccacctc caggtgccgt tcctggccga
    12301 cctggtcacc ctcgccgacc ccagctcccc cttctcgttc ctgaactacc tcaaggaatc
    12361 ggggcggctg tactcgttct acatccgcga gaacttctat ccgctgcgcg ccgagttcaa
    12421 cgactactgc cgctgggcgg ccggcaaact cgactccgtc cgcttcgccc accgggtcac
    12481 caccgtcgaa tacgacgcac gcgaagagct ctacaccgtc cacgccgagc agcccaccgg
    12541 cgaacgtcac accttccgcg cccgcaggct cgtcctgggc accggcaccc cgccgtatgt
    12601 ccccgacgcc tgccgggacc tgggcggtga tctgctgcac aacgccgggt acctcgacgc
    12661 caaggccgcc ctccaggcca aggacagcat caccctcatc ggcagcggcc agagcgcggc
    12721 cgagatctac tacgacctcc tccaggacat cgacagccac ggctaccacc tgacctgggc
    12781 cacccgctcc ccgcgcttct tccccctcga atacaccaag ctcacgctgg agatgacctc
    12841 cccggagtac gtggactact tccacgccct cccgccggcc acccgcgacc gcctcaacgc
    12901 cacccagaag cacctctaca agggcatcga ctccgagctg atcaacgaca tcttcgatct
    12961 gctctaccag aagaacctgg ccggccccgt ccccacccgg ctcctgacca acaccgccct
    13021 gcaccaggcg agttacgacg agacgtccgg cacctacacc ctgggcctgc gccaggagga
    13081 acagggcacg gacttcgccc tcgacaccca gggcctgatc ctcgccaccg gctaccgcta
    13141 ccgcgtaccg gacttcctct cccccgtccg cgaccgcatc gtctgggacg acgccggccg
    13201 ctacgacgtc gcgcgcaact acagcatcga caccaccggc cagggcatct tcgtgcagaa
    13261 cgccgagctg cacacccatg gcttcgtcac ccccgacctc ggcatggccg cctaccgcaa
    13321 cgcgtgcatc atccgcgagc tgctcggccg cgagtactac ccggtcgaaa aggccatcgc
    13381 cttccaggag ttcgccgccc cggccggccc gcaccacccc atggagctcc cggcatgacc
    13441 acccccctct tcacccgcac cgacgccgcg ctcggggagt tctcgctccg cccggtcgac
    13501 ccgtacggcg acgccgaact gctgcaccgc tgggtcaccc accccaaggc cgccttctgg
    13561 ctgatgcagg actgcgacct cgccgccgtc gagaaggaat tcgcgcgcat atccgccgac
    13621 cccttccacg acgccttcct cggcctgcac aacggcaccc cggccttcct catggagcgc
    13681 tacgaccccg cacaccgcga actcgtcggc atccacgccg ccgaacccgg cgacgtcggc
    13741 atgcacttcc tgtcggcgcc caccgacacc cccgtgcacg gcttcaccct cgccgtgatc
    13801 accaccgtca tggagatgct cttcgccgac ccggacgccc gccgcgtcgt cgtcgagccc
    13861 gacgcgcgca acaccgccgt ccacgccctc aacaaggccg tcggcttcga ggtcctgcgc
    13921 accgtctcgc tcccctccaa agacgcctac ctcagcacct gcacccgcga ccagttcctg
    13981 gccacccgag gagaccaccg atgaccgccc cctccgacgg caccccgcac ctgtccgccc
    14041 gggacgccgt cgcccacctc actcccggtc tgtgggcccg cgccaaccgg ctgctgatcc
    14101 gcaagggcct cgccgagttc gcccatgagc ggctgctcac cccccggcgc ctcccgcagg
    14161 acggccacta cgccgtacgc agcgacgacg gcgccaccga gtaccgcttc gccgcccgca
    14221 gacgagccct ggaccactgg cagatcgacg ccgacagcat cacccggcac cgcgaccacg
    14281 acgaactccc cttggacgcc ctggcgttct tcctcgaact ccgtgactcc ctgggcctcg
    14341 gcgaggcgat cctcccggtc tacctggagg agatcagctc caccctctcc ggcaccgcct
    14401 acaaactcgc cgccggccgg ccctccgccg cggagctcgc gaaggcggac ttccaggccg
    14461 tcgagaccgg catgaccgag ggccacccct gcttcgtcgc caacaacggc cggctcggct
    14521 tcggcatcca cgagtaccac gcctacgccc cggagaccgc ggccccgctc cggctgatct
    14581 ggctcgccgc ccaccgcgac catgccacct tcaccgccgg cgccggcctc gactacgacg
    14641 ccctgatccg cgacgaactc cccgacacca cccgcgcccg cttcaccgcc accctcacca
    14701 ccctcggcct cgaccccgcc gactactact tcttccccac ccacccctgg cagtggtgga
    14761 acaagctctc cgtcaccttc gccgccgaag tcgcccggca gcgcctggtg tgcctgggcc
    14821 ccggtgacga cgactacctg gcccagcagt cgatccgcac cttcttcaac accaccagcc
    14881 ccaccaagca ctacgtcaaa acggccctct ccgtcctcaa catgggcttc atgcgcggtc
    14941 tgtccgcgtc ctacatggag gccaccccgg ccatcaacga ctggctggcc cgcctcatcg
    15001 acgccgatga caccttccgg gccgcccgct tctcgatcat ccgggagcgc gccgccctcg
    15061 gctaccacca ccggcagtac gaggccgcca cggccaaggg ctccccgtac cggaagatgc
    15121 tcgccgccct gtggcgcgag agccccgtcc ccaccatcga accgggtcag cgcctggcca
    15181 ccatggcctc cctcctgcac accgacgagg acggcggctc cctcgccgcc gccctcatcg
    15241 aggagtccgg cctggaaccc gccgtctggc tccgccgcta cctggacgcc tacctcacgc
    15301 ccgtactcca cgccttctac gcctacgacc tggtcttcat gccgcacggc gagaacgcca
    15361 tcctggtcat cgaggacggc gccgtggccc gcgtgatctt caaggacatc gccgaggaga
    15421 tcgccgtcat ggaccccgac gcggtgctgc cgcccgccgt cgaacgcatc cgcgccgatg
    15481 tccccgagga caagaaactc ctgtccgtct tcaccgacgt cttcgactgc ttcttccgct
    15541 tcctcagcag catcctcgac gaccacggca tcctcgacga ggacaccttc tggcgcacgg
    15601 tcgccgcctg cgtcaccgac taccaggcgg ccacccccca gctcgccgac aagttcgagc
    15661 gctacgacct cttcaccgac gagttcgcgc tctcctgcct caaccgcctc cagctgcgca
    15721 acaaccagga gatggtcgac ctccaggacc cggcgggcgc cctccagctc atcggcaccc
    15781 tccgcaaccc cctcgccccc tacgctccgg cctcctgacc gcacccccac acgccgaagg
    15841 gcgggacccc tccccggggt cccgcccttc ctcatgcgtc acatcggctc agccgacggc
    15901 cggctcagtc cttcgcggaa ccggcctcgc cctgggcgcc gtcgtcctcg gccgcgtccg
    15961 cctcgtcggc ctcgtcggcc tcttccagcg cgtcggtgaa ctccacaccg tccagctccg
    16021 cgagccggtc cgaggcgtcc gtcgtaccgc cctggtcggc ctccagcgcc ctggcgaacc
    16081 agtcgcgcgc ctcgtcctca cgcccgaccg ccagcagggc atccgcgtac gcgtagcgca
    16141 gccgcgccgt ccacgggtgc accgcactcg acgcgagttc cgggctctgg agggtcacca
    16201 ccgcggcgtc cgcctggccc atgtcccgcc gggcacccgc cgcgaccagc cgcatctcga
    16261 cctggccggc cttgtcgagc ttctgcacct cgggctcacc ggccatggcc atcgccttct
    16321 ccggacggcc gagaccacgc tcgcagtccg ccatgacggg ccacagctcc acgctgccgg
    16381 tcatccgccg cgccgcccgg aactccgcca gcgcctcgct gtacttgccg accgcgtacg
    16441 ccgcgaagcc cgcggcctca cgcaccgccg cgaccctgga cgccagccgc agcgccaccc
    16501 gcgagtagcc gtaggcctgc tccgggtcct cgtccagcag cttcgccacc atcaccaggt
    16561 tcttggcgac atcatcagcc agcgtcttcg gcaggctcag cagctcctga cgcacatcct
    16621 tgtcgatctc gtccccggtg acatcctccg gaatcggcag ccgcttgatc ggctcccgat
    16681 cccggtcccg ccggtcatca cggcgatcgt cccggcggtc atcccgcccc cggccaccgc
    16741 cgtacggccg acgcccccca cgctcgtcat cccgccggaa ccccccacgg tcatcgcgcc
    16801 gcggcccacg gtcgtcccta cggaacccac cccggtcacc accgcggtcg tcccgacggt
    16861 cgccaccgcg gtcatcgcgc cggtcaccgc cacggacccc cccacggtcg ccacccgacg
    16921 gccggtcgtc ccgccggaag ccaccacggt ccccgccgcg atcatcgcgc cggtcaccac
    16981 cgcggtatcc accacggtcg tcccgccgga agccgggacg gtccccaccg cggtcgtccc
    17041 gccggaagcc gggacggtcc ccaccgcggt cgtcgcgccg gaacccgcca ccacgctcat
    17101 catcccgccg cggcccacgg tcatccctac ggaagccacc acggtccccg ccgcggtcgt
    17161 cccgccggtc gccaccacgg aacccaccac ggtcgccacc cgacggccgg tcatcacgac
    17221 ggaacccacc ccgatcgcca ccacggtcat cacgacggaa gccgccgcgg tccccaccac
    17281 ggtcatcgcg acggtcacca ccgcggtaac caccacggtc gccaccggac ggccggtcat
    17341 cacgacggaa cccaccgcgg tcatcacgac ggtcgtcacg gcggtcgtca cggcggaagc
    17401 caccacggtc gccaccggac ggccggtcat cacggcggaa tcccccacgg tcaccaccat
    17461 gggaacggtc gtccctacgg aaaccgccgc ggtctccacc gcggtcatcg cgacggtcgc
    17521 caccgcggta accaccgcga tcgccaccgg acggccggtc atcacgacgg aacccaccgc
    17581 gatcatcccg ccggtcgccg ccgtacgaac ggtcatcccg ccgcggcccg cggtcatccc
    17641 tacggaagcc gccacggtcc ccaccgcggt cgtcccgccg gtcgccaccg cggtatccac
    17701 cacggtcgcc acccgagggg cggtcatcac gtcggtaacc tccgcggtca ccaccacggt
    17761 tgtcgccacg cgacccgcgg tcgtcacgcc ggaaaccacc gcggtcgccg tcgtcgcgcc
    17821 gctgcggccg gcgctccgaa cgatcgtcgg aagaattggt ggacatcgac gtgactcctg
    17881 tcttcggtac tgcattcatt ctcgcgcacc gaccagttcg gcgcgcttcg gaaaaacaaa
    17941 aaggaccctt ggtcccagcg tgaacgctgg gaccaagggt cctgaaagat tgttcggcgg
    18001 cgtcctactc tcccacaggg tcccccctgc agtaccatcg gcgcggaaag gcttagcttc
    18061 cgggttcgga atgtaaccgg gcgtttccct aacgctatga ccaccgaaac cctatcgggt
    18121 tctagcgaac aagcacactt tttagttaaa gagtgaaact tggttcaacc agcgattgcg
    18181 actgttcgca acccgggaac cacacagtgg acgcgagcaa ctgaggacaa gccctcggcc
    18241 tattagtacc agtcaactcc acccgttacc gggcttccat atctggccta tcaacccagt
    18301 cgtctactgg gagccttaac caatcaagtt ggtgggagcc ctcatctcga agcaggcttc
    18361 ccgcttagat gctttcagcg gttatccttt ccgaacgtag ccaaccagcc atgcccttgg
    18421 caggacaact ggcacaccag aggttcgtcc gtcccggtcc tctcgtacta gggacagccc
    18481 ttctcaagac tcctacgcgc acagcggata gggaccgaac tgtctcacga cgttctaaac
    18541 ccagctcgcg taccgcttta atgggcgaac agcccaaccc ttgggaccga ctccagcccc
    18601 aggat
//
