LOCUS       NZ_BBNO01000005        22619 bp    DNA     linear   CON 19-AUG-2024
DEFINITION  Streptomyces lydicamycinicus strain TP-A0598, whole genome shotgun
            sequence.
ACCESSION   NZ_BBNO01000005
VERSION     NZ_BBNO01000005.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces lydicamycinicus
  ORGANISM  Streptomyces lydicamycinicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Komaki,H., Hosoyama,A., Igarashi,Y. and Tamura,T.
  TITLE     Streptomyces lydicamycinicus sp. nov. and Its Secondary Metabolite
            Biosynthetic Gene Clusters for Polyketide and Nonribosomal Peptide
            Compounds
  JOURNAL   Microorganisms 8 (3), 370 (2020)
   PUBMED   32155704
  REMARK    DOI:10.3390/microorganisms8030370 Publication Status: Online-Only
REFERENCE   2
  AUTHORS   Komaki,H., Ichikawa,N., Hosoyama,A., Fujita,N. and Igarashi,Y.
  TITLE     Draft genome sequence of marine-derived Streptomyces sp. TP-A0598, a
            producer of anti-MRSA antibiotic lydicamycins
  JOURNAL   Stand Genomic Sci 10, 58 (2015)
   PUBMED   26380643
  REMARK    DOI:10.1186/s40793-015-0046-5 Publication Status: Online-Only
REFERENCE   3  (bases 1 to 609884)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: Newbler v. 2.6
            Genome Coverage                   :: 93x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000829715.2-RS_2024_08_19
            Annotation Date                   :: 08/19/2024 02:08:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,323
            CDSs (total)                      :: 7,237
            Genes (coding)                    :: 7,092
            CDSs (with protein)               :: 7,092
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 54 of 145
            Pseudo Genes (incomplete)         :: 123 of 145
            Pseudo Genes (internal stop)      :: 9 of 145
            Pseudo Genes (multiple problems)  :: 39 of 145
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:07:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 303303
            Orig. end                         :: 325922
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBNO01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22619
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22619
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22619
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12619](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12619)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    176..194
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.71"
                     /tool="antismash"
     gene            complement(918..1082)
                     /locus_tag="TU31_RS39820"
                     /old_locus_tag="TPA0598_05_02880"
     CDS             complement(918..1082)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TU31_RS39820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TPA0598_05_02880"
                     /product="hypothetical protein"
                     /protein_id="WP_245698600.1"
                     /transl_table=11
                     /translation="MVSSFGWGEEMSDPGAPKGVAAWVMTVSYLPLLAWGPLLGWVTVA
                     YWHRRRRAG"
     gene            complement(1088..1438)
                     /locus_tag="TU31_RS19060"
                     /old_locus_tag="TPA0598_05_02890"
     CDS             complement(1088..1438)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TU31_RS19060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TPA0598_05_02890"
                     /product="hypothetical protein"
                     /protein_id="WP_245698601.1"
                     /transl_table=11
                     /translation="MTTPAVRPLVPRPVRWAAHAAPLTLLPSGLWRCAIAFGVPSGFDV
                     SHPLHRSNFPGWTSLYLIGLSLVAEGLGLLTLGLVQPWGERVPRRVPVLAGGAFPSRPP
                     WSPPHWAPPRSP"
     gene            complement(1435..2049)
                     /locus_tag="TU31_RS19065"
                     /old_locus_tag="TPA0598_05_02900"
     CDS             complement(1435..2049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092232.1"
                     /locus_tag="TU31_RS19065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_02900"
                     /product="hypothetical protein"
                     /protein_id="WP_078885851.1"
                     /transl_table=11
                     /translation="MAVLVGLTGSTPAASAAPSGAAAVSKAPTGLARVSGQARVFYAYS
                     PHDEIRFSVDATAAPFSRPVGGLPQGMPTDARGTVTVSHWSPGKGQGRRAEAAVDCLVT
                     GGGTATLSARVTKSEDPDEIGERLGFSVTSGGPGKGRIGFSWAVSNVDVVNGKAVFPHV
                     GTCMAPAPFAAVTKGGFKVRHAELPPLPTGWGKQAEGAGTR"
     misc_feature    complement(2366..2379)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.47"
                     /tool="antismash"
     gene            2639..3826
                     /locus_tag="TU31_RS19070"
                     /old_locus_tag="TPA0598_05_02910"
     CDS             2639..3826
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="TU31_RS19070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_02910"
                     /product="sensor histidine kinase"
                     /protein_id="WP_158894534.1"
                     /transl_table=11
                     /translation="MTTVACDPPSAPWGSVWRLAEMAMLLMLLAVVARWAPLRQAVIAA
                     VVAGVAVATWTLPLVPDPSVLPLAGAAAFWTLPVLGAAVVGGYPRLVENRRRRLVIETR
                     RSQQLELAQDLHDFVAHDISGIVAQAQAARFVAESDPGQALPALERIERAGLNALASMD
                     RTVRMLHEAHGNGISRPDAPTPPQARPATDDPRPSEAHQPPPASQTPDALNSPPAAPPP
                     QQAPTLPAPPLDSTPHPEPLPGVAQLPTLIARFTSAGATEARLTMPPTTPETLSRETSS
                     TAYRMVVEALTNVRRHAPGSARVEVTLTPATGSDLTAHPRVPTLEIQITNDAGTAPATA
                     LRARRQRAGHGGRGLASLRARVQATGGTLTYGPHDGGWRLRAVLPQTHPLPPETT"
     gene            3823..4503
                     /locus_tag="TU31_RS19075"
                     /old_locus_tag="TPA0598_05_02920"
     CDS             3823..4503
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092230.1"
                     /locus_tag="TU31_RS19075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_02920"
                     /product="response regulator transcription factor"
                     /protein_id="WP_042156133.1"
                     /transl_table=11
                     /translation="MSGTPTRILLADDQDDVRSGFRLVLDSQPDMTVIGEAADGATALE
                     LARHLRPDVVLADIRMPRLDGLELTRLLAGPESPRPTKVVVVTTFDLDDYVHTALHHGA
                     CGFLLKRSGPNLLIEGVRAAMAGDALISPQITVRLLRRLSPPPPSHPHPHPGPGPDALT
                     DRERDIARLVARGLTNQEIATELVISAGTAKTHLANIQAKLKLRNRVEIAAWSWRTGLT
                     PPAS"
     gene            complement(5059..5832)
                     /locus_tag="TU31_RS19080"
                     /old_locus_tag="TPA0598_05_02930"
     CDS             complement(5059..5832)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016472681.1"
                     /locus_tag="TU31_RS19080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_02930"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_042156136.1"
                     /transl_table=11
                     /translation="MIPSHPPLGRPDHPPAAAARDLTKVHDMGGHQVTALDQVSFDVHQ
                     GHFTAIMGPSGSGKSTLMHCLAGLDSPSSGAAWIGEVNLAKLSDRQLTLMRRDRIGFIF
                     QAFHLLPTLTVMENITLPMSLAGKRPDQQWLTEVIATLGLRERLAHRPPQLSGGQQQRV
                     ACARALLNQPEIIFADEPTGNLDSRAGAEVLRLLRESVQQLGQTIVMVTHDPVAASYAD
                     RVVFLADGRIVDELQQPTADGVLDRMRMFDPMDGA"
     gene            complement(5829..7178)
                     /locus_tag="TU31_RS19085"
                     /old_locus_tag="TPA0598_05_02940"
     CDS             complement(5829..7178)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="TU31_RS19085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_02940"
                     /product="MFS transporter"
                     /protein_id="WP_158894537.1"
                     /transl_table=11
                     /translation="MPSRPTLGRPFWLLFGGEAASAFGTSASIVALPVVALQASGDVRE
                     AGLASTALSAGVLLARLPAGVFADRFDRRALLLGGNLLGAAILVTLALVQARDALSLPV
                     LTLAALLLGMVGSTLSPAENVAIRSFVHPDLLARALSLTQARTAATLIAGPAAGGALLA
                     TQPVWVFALDAATYLVAAVCMAALPSRAGPVGVGRPTLKAACEGIRFLWRSPFLRYAAV
                     NAAVLNLVFNGLLIVVIASADGGAQAALGIGAQTAAIGAGALGGSLIAAPAARRLPATR
                     GIALSTGVIAVALVGFATVHDSWAAAFLLALASACGPVVTVLLATVQIRMTPAELQGRV
                     HSGTGFLAQAISPLGPTLAAVSTQAFGLFPTVLGAALLVVLLALAGGAITARHLHASPP
                     YTAGHTTADGAGADRADARGTDGAEPTATGRHQGRRSETDGQELQMRSRA"
     misc_feature    complement(7068..7070)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7184..9136)
                     /locus_tag="TU31_RS19090"
                     /old_locus_tag="TPA0598_05_02950"
     CDS             complement(7184..9136)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014717.4"
                     /locus_tag="TU31_RS19090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_02950"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_042156141.1"
                     /transl_table=11
                     /translation="MSAALPTPPPLTITRATPTRLLLSEIRAYPGRVIGAATACCATAA
                     GVGACLLLLLGASLADHPADSPEAAAAKSTQDIMALLMSLLLMCAVLVIGSTVSLWTGQ
                     RLRQFAVLRALGMTAARLRRMAAVDVARLALVSAAFGTAAGALPLAGLGRRILIEQKLF
                     PAATELPPPAQTWGACVAVCLGTVVISVLAALLSVRAAGRVNAIDLLKDHEGGPGTKRS
                     RARLITGLSMAALFCAPLLVVMAVPGLPPKVRAGVAPGLALFVIPTLAVLAPWVIPPLT
                     GPVCAVLRVLDRRVGTIAAAGLRATPARTTALAVPVLLSAGVTACLLGGGTTMGRAAQQ
                     EVEAALRADAVISAEPGARLPATPGPLSGATATPVIATKVTVPGPKRRSAPKPTRAWGV
                     DGRVLSRVVNLSEREGDITKVGEGTFAAGAEFADQAKWKVGQSVELTLADATPKRLTLV
                     AVYARDLAFPHMILPRATALAHTTSPTADRIFLTGPSSAWPVAKGQTIASREDYAQTFT
                     RSPADDLATRLIAAVVAAYALLAAANTSALAQRDRVAQRAHLRALGLSRFQMLRCVLYE
                     ALGAGAIGVVLSGLVAVVCLVPLSVTLGLGPLPTFDGPWTVGVLAGAVVALGVPAAMTA
                     HPLLSVQRQFARSGQ"
     misc_feature    complement(8651..8653)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     assembly_gap    9234..9920
                     /estimated_length=687
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(10001..12619)
                     /gene="lanKC"
                     /locus_tag="TU31_RS19095"
                     /old_locus_tag="TPA0598_05_02970"
     CDS             complement(10001..12619)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="TU31_RS19095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_02970"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_078885854.1"
                     /sec_met_domain="micKC (E-value: 1.4e-197, bitscore: 653.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 4.1e-14, bitscore: 47.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 9.1e-11, bitscore:
                     36.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYVDRGTGVRAHLAPSAPLNEDSPRARENGGEVDPNYGPYIVAD
                     SNWYEPLERCDDAASRFSLTKREFPVEWKRSRQGVWEVLAPVGGQRLPQQGWKIHITAT
                     PDTAEEVIEQTWAVCRRLNLPWKFLRSRRIMTVLNSKYANRAASGKVVTVYPRDAEELH
                     TALTELDAVLGGRPGPYILSDHRWNKGPVSVRYGAFALMWCELPDGSRVPALHDPQGNA
                     VPDRRRPAFTVPEWAETPGFLTTSLAAAAAEDPAATLKGYTVLKALHFSNGGGVYLAKA
                     PDGTQVVLKEARPHAGLDAAGADAVDRLRNEWSALKTVGHLPFVPRPIEYFAAWEHHYL
                     AMEHIQGHSLSTWMGRDYPLTRHAPDERARAEYTARALDYLGQAEAAIETLHKAGMAFG
                     DLHPHNILIRDDGTVALVDFEIATAVDTKRTTVLGAPGFIDLSLTNARDSDLYSLGCCQ
                     LTVFMPLTGLVQRTPEVIGHLIEMATTAFPTLPAAYVERTAKRLALSPNVRPHLPGHRA
                     DAVPPLAPPRAAPLLRGISKSADTTRIDRLFPGDIAGHREGATLGLAYGTPGVLLAQLS
                     AGSSVDPEHLTWLEHAARRAPARTPLGLYDGLAGTAWLLHRLGNPLGEELIDRILSSRL
                     PSSPGLFNGLTGIAHLLLDAGMRDEALKLAAAIRARIGDDGVLDRPGLMYGWSGPAVLL
                     ARCARLTGDEEWAEAAATAVRADLKHARQLDGTLQMSSSHRLLPYLAEGSGGVALAAMA
                     LPETQAAAIGAYDIVAGAAHATAVHTVSQGGLFNGRAGNIYFLSHAAAHIRQARSWAEN
                     QLRLLSLHVADHDGGQALFGDQLLRLSIDLATGSAGVLLAMEAAKTPGARLLPGAHPDQ
                     G"
     misc_feature    complement(12344..12346)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12605..12619)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(12663..13721)
                     /locus_tag="TU31_RS35985"
                     /old_locus_tag="TPA0598_05_02980"
     CDS             complement(12663..13721)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024248.4"
                     /locus_tag="TU31_RS35985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_02980"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_052718984.1"
                     /transl_table=11
                     /translation="MQHITLCADDLARIRITYPIGQQVEAIFAVDALRNTKSEFFRTWR
                     RRVNARILHAGQRLDGVRRLARVRGGSREILSDWLGGADTSDTNHSGILGVQQSQLLAA
                     VEDMRQVAVQPYWNRIYEHLASTQDFRRDIMCGDGIEVLLNSLGPGIRWAAPVLEIDSE
                     STAHLKPNGRGLLLSPSLFLQDSGAVLPSPPGIADGSPVLIFPDRPSDQCGLFPDEGLS
                     SVPAAARRPQESLAGLVGRTRAAVLHALRDGCSNGDLAQKLGVSPAAVSQHTATLRNAG
                     LISTRRSGSQVVHTVTTLGRHLLRDGSDSGELCGHVAPGPRTADFAPACGGLRPRTPDA
                     LRAPPPVIRRSA"
     misc_feature    complement(13416..13418)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(13419..13421)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(13482..13484)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13771..13782
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.15"
                     /tool="antismash"
     tRNA            complement(15218..15293)
                     /anticodon=(pos:complement(318561..318563),aa:Arg,seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="TU31_RS19105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="TPA0598_05_t0050"
                     /product="tRNA-Arg"
     gene            complement(15218..15293)
                     /locus_tag="TU31_RS19105"
                     /old_locus_tag="TPA0598_05_t0050"
     gene            complement(15413..15745)
                     /locus_tag="TU31_RS19110"
                     /old_locus_tag="TPA0598_05_03000"
     CDS             complement(15413..15745)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605033.1"
                     /locus_tag="TU31_RS19110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_03000"
                     /product="hypothetical protein"
                     /protein_id="WP_042156145.1"
                     /transl_table=11
                     /translation="MTTLSEAIRTTPAKPARTTEPTQADDPATSRLRRHADGMAVASFV
                     LGLLGTLVLNLLLGPCALVLGTLALTRGTTRRGRALLGLTLGATDLLILALLATTDGTV
                     SWHIGG"
     gene            complement(15742..15906)
                     /locus_tag="TU31_RS39185"
                     /old_locus_tag="TPA0598_05_03010"
     CDS             complement(15742..15906)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091193.1"
                     /locus_tag="TU31_RS39185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_03010"
                     /product="small hydrophobic membrane protein"
                     /protein_id="WP_042156147.1"
                     /transl_table=11
                     /translation="MLFLVAALLLMGILLGTAAHLPVPVTLVAAAVIAGWLLVFFLRER
                     RHNDEVTSR"
     misc_feature    complement(15901..15916)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.7"
                     /tool="antismash"
     gene            16010..16666
                     /locus_tag="TU31_RS19120"
                     /old_locus_tag="TPA0598_05_03020"
     CDS             16010..16666
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091192.1"
                     /locus_tag="TU31_RS19120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_03020"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_042156648.1"
                     /transl_table=11
                     /translation="MSHSLGVRQAQKQKTRQALLDAALGLLEEQSLSSLGLREVTRSVG
                     VAPTAFYRHFRDMGELGVALVEEALGSLHVMVRAILAEQDGAEERIDRTVAVVQQHVRH
                     HPLHIRFVARERHGGVRDVRLAIAGELDRFAEEVAAALKSQPVSEGWRDDDVRMLAELY
                     VDRLVTTAAALLDAEADGAEGAAEQVVRVARRQLRLISVGRRHWLAEGRGKGDTP"
     gene            complement(16663..17910)
                     /locus_tag="TU31_RS19125"
                     /old_locus_tag="TPA0598_05_03030"
     CDS             complement(16663..17910)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091191.1"
                     /locus_tag="TU31_RS19125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_03030"
                     /product="M6 family metalloprotease domain-containing
                     protein"
                     /protein_id="WP_042156149.1"
                     /transl_table=11
                     /translation="MKHKVSAVLAAGAATAAAAIALGSPPSAVAIPSVPGAPPSGPCAL
                     RGISDDVAESAETPAGFSRSSGTVEALTLFIDFPDARATMSPRDRFAEFFPAATDYFRT
                     SSYGRLTYRPRPLLRWIRMSRPLAAYGIQRGAGFDPASDGGYHALSREVVRAVDPLVDF
                     RDYDVINIIATPNAGPPATRTVLSVTFSGGDMGLRTADGVPFRNASFIWSRQTGASAFR
                     VLNHENAHSFGLPDLYFTDGRDAPPPAGHWDPMDEDWGPSNDFVGWHKWKLGWLSADQV
                     HCVPHRGTPGEHTLTPVSARGGTKIVVIPTSPHTALVAEARTRGLLDPTVCRPGILIYR
                     VATHVPSGRGPLRIVDATPHSGGCYRDNKYVDPELTDATFRPGDTYTDRTTGAAVTVLT
                     ENPDGTYRVRVTPARA"
     misc_feature    complement(18007..18022)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     gene            18171..18830
                     /locus_tag="TU31_RS19130"
                     /old_locus_tag="TPA0598_05_03040"
     CDS             18171..18830
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605037.1"
                     /locus_tag="TU31_RS19130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_03040"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_078885855.1"
                     /transl_table=11
                     /translation="MTAAARVKSGKQEQQPRLRADALRNRERIIAAARETMVEFGAEVP
                     LDEIARRAGVGNATLYRHFADRLELIHHVTLSVMSRTADRAESALAEESDAFQALRRFV
                     HAAVEERIGALCPLLADGVDRDHPDLCAARDRLEAAVEAVMAAARDSGRLRTDIAVGDL
                     MVAITQLTRPLPGSRCPDFDQFVHRHLQLFLDGLQAPARSELPGAAATLDDLRRRS"
     gene            18916..20454
                     /locus_tag="TU31_RS19135"
                     /old_locus_tag="TPA0598_05_03050"
     CDS             18916..20454
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605038.1"
                     /locus_tag="TU31_RS19135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_03050"
                     /product="MFS transporter"
                     /protein_id="WP_042156152.1"
                     /transl_table=11
                     /translation="MPETVPSVDPRRWKALIFIALAQLMVVLDATIVNIALPSAQQDLG
                     ITDANRQWVITAYALAFGGLLLFGGRVADLWGRKRTFIIGLVGFAVASALGGAAANQGM
                     LLGARALQGVFGALLAPAALSLLAVTFTEAKERAKAFGIFGAIAGGGGAVGLILGGVLT
                     EYLNWRWTFFVNIPFAVVAATGAFLVIREPAEGRNPSRLDIPGVILATLGLVSLVYGFT
                     RAESDGWLAGPTLGLFAAAAVLLLAFVLVEARVKAPLLPLRVLTDRNRAGVYASLGLAV
                     IGMFGLFLFLTYYLQIVKGYTPVTTGLAFLPMIVGMVTGSTQIGARLMTRVRPRLLMAP
                     GFTVAALGMLVLTRIDLDTSYPALILPGFLLMGLGMGTAFMPAMSLATHGVQPRDAGVA
                     SAMVNTSQQVGGAIGTALLNTIAASATTAYATSHAAGAHSADLLKLQAMVHGYTTAIWW
                     AVGILALAGVIAFTFINTGRPGAGSPAASSAEEERTVLGSSEGRDEIQVPVMAH"
     gene            complement(20616..21113)
                     /locus_tag="TU31_RS19140"
                     /old_locus_tag="TPA0598_05_03060"
     CDS             complement(20616..21113)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091188.1"
                     /locus_tag="TU31_RS19140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_03060"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_042156153.1"
                     /transl_table=11
                     /translation="MSNEPAAEPRWLSDEEQFAWQCYLHATTLLEDHLDRQLQRDAGMP
                     HVYYGLLVQLSRAPRRRMRMTELAQNAKITRSRLSHAVARLEKNGWVRRENCPSDKRGQ
                     NALLTDEGMRVLEKAAPGHVAAVRSAIFDRLSPEQVGQLAEICQVMTEGLQPKGADLPW
                     LR"
     gene            complement(21317..22366)
                     /locus_tag="TU31_RS19145"
                     /old_locus_tag="TPA0598_05_03070"
     CDS             complement(21317..22366)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979563.1"
                     /locus_tag="TU31_RS19145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_05_03070"
                     /product="questin oxidase family protein"
                     /protein_id="WP_042156155.1"
                     /transl_table=11
                     /translation="METTNRTLDEALLRLHTAGPEFGGYLSNHGPMAVEAMVRNGQART
                     VHRWLDTYARKLEDVPAPQGRITDTNWQQALGDPGRVTDWTGYFTEQIAERPWRALLAE
                     WWPRLLPGIAGAATHPVIRVGHAVRSLLTEGEDEARIAELAHALGYWAARHLLLPTTVR
                     PQGGATPAEALAALPRITERNVMPLNGYAQLPHISGWLSTTESLHIPEDPEAAREGLTA
                     LVRAATLNYADHGHGHGILLVHAATAPNAVLRTLPALPRELWAGSFAVAWAAASALTTL
                     YAADTARPAPSAAGLAPEEVFERAVTHGDEHAIKFADTALDVAAASEDGDSRALSAALN
                     AMALIDKAD"
     misc_feature    complement(22328..22330)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 cggatcgagc cccgcgtgat acggcaccgc cgcgatgccg ttgtccacca ggaactgcgc
       61 ggtcttctcc accgacgccc gcgacaggca gtagacgatc ccggcgtctc cggcgtgctc
      121 gttccgcagc agctccagga gctgcttctt cggctcgctc ttcgacgcga tccggtactg
      181 gatgttcggc cggtcgaagc tcgccacgaa atgccgggcg tccgccatcc gcagccgtga
      241 ggtgatctcg gtatgcgtgg cctcggtcgc ggtggcggtc agcgcgatcc gcggcacctc
      301 gggccaccgc tcgtgcagca tcgacagcgc cagatagtcc ggccggaagt catggcccca
      361 ctgggcgaca cagtgcgcct cgtcgatcgc gaagagggag atcttcccgc ggtcgagcag
      421 attcagcgtc tgctcgaccc gcagccgctc gggcgccaga tacagcagat ccagctctcc
      481 ggccaggaac tccgcctcga cgagccgacg ctcctccaga tcctgcgtcg aattcaggaa
      541 cccggcccgc acaccgagcg cccgcaaggc gtcgacctgg tcctgcatca acgcgatcag
      601 cggcgagatc accaccccca caccgcttct gaccagcgag ggaatctgat aacacagcga
      661 cttgccgcca ccggtgggca tcaggacgac cgcgtccccg ccccctatga cgtgctcgat
      721 gatctcctgc tggctgccgc ggaacgcgtc atacccgaac acccggcgca gcacctgcac
      781 cgcctcgcct gcgtccgaag cgccttccac atccatgtcc acgaccactt ccacgtccgc
      841 cagagccatt ccgaaagcct acgagcttcg cgggggtccc cgtcgaccct gtggataact
      901 cacaccgtcc ggcgccgtca gccggccctg cggcgccgat gccagtacgc caccgtcacc
      961 caccccagaa gcgggcccca ggccagcagc ggcagatagg agacggtcat cacccaggcc
     1021 gccacgccct tcggggcgcc ggggtcggac atctcctcgc cccagccgaa cgacgacacc
     1081 accgtgatca cggtgaccgc ggcggcgccc agtgaggcgg ggaccacggc ggccgggacg
     1141 ggaatgcgcc gcccgccagg acgggcaccc ggcgcggcac ccgctcgccc catggctgga
     1201 ccagtccgag ggtgagcagc cccagcccct cggcaaccag gctcagcccg atcaaataca
     1261 gcgacgtcca cccggggaag ttgctccggt gcagcggatg actcacatcg aacccggacg
     1321 gcaccccgaa ggctatggcg caccgccaca gccccgacgg cagcagcgtc agcggcgcgg
     1381 catgcgccgc ccaccgcacc ggacggggta cgagcgggcg caccgcgggc gtcgtcatcg
     1441 ggtgccggcc ccctcggcct gcttccccca ccccgtcggc agcggcggca gctccgcatg
     1501 cctgaccttg aagccgccct tcgtcaccgc ggcgaaggga gccggtgcca tacacgtgcc
     1561 gacatgcggg aagacggcct tgccattgac gacgtcgacg ttcgacacgg cccaggagaa
     1621 gccgatccgc cccttgccgg gcccaccgct cgtgacgctg aagcccagcc gctccccgat
     1681 ctcgtcgggg tcctcggact tggtcactct ggcgctgagc gtcgcggtgc cgcccccggt
     1741 gaccaggcag tccaccgcgg cctccgcacg ccggccctgc cccttcccgg gcgaccagtg
     1801 ggagaccgtg acagtgcccc gtgcgtcggt gggcatcccc tgaggcagcc cgccgaccgg
     1861 ccggctgaac ggggcagctg tcgcatcgac ggagaagcgg atctcgtcat gcggcgagta
     1921 ggcgtagaag acgcgcgcct ggccactcac ccgggcgagc ccggtcggcg ccttcgagac
     1981 ggccgcggca cccgagggag cagcggacgc ggcgggcgta ctccccgtca gcccgacgag
     2041 cacggccaca gcggcaccgg ctcccactac ggccctacga cggcgagaac tggcgaagcc
     2101 cgtaccggcg aggcacgacg aacgaacgga agaagtaatg ccgggcacga tgaactcctt
     2161 caatacgcag cagccttgac ggccaccgcc ctgtcgatga cacctcccat ctgacgccgg
     2221 gccgcggcgc ccggccatct gccgatcagc ggattccggg cgccgaagcg ggcgtcctct
     2281 ctgccgttcg gcggagggag tgcccgggcg gccgctcgta ggatcgacgg cgtgggccga
     2341 tgcacgcctt gagcagccag ggcggcgcat ggccatacag cgatacgggg gctgtgcccg
     2401 cccgtggcgg gcggtacatg gggggtgggc ctggatgagg cgtcacatgg ggacgggctt
     2461 aacgggctgc gcagccctgc tcgctttccc cctcgcgtac ggcacctggc cggcggtccc
     2521 ctacggagcc gtcccggccc tcgcgtccgc cgccctgctc ctctgggccg ttgcccgttg
     2581 gccgggctcg cgtgaccgcc tcgctcgccc gttggcgctc gtcggaagcc tgtcgctgat
     2641 gaccacagtg gcctgcgacc ctccgtcggc gccctggggg tccgtatggc ggctggccga
     2701 aatggcgatg ctgctgatgc tccttgccgt agtggcgcgt tgggcgccgc tccggcaggc
     2761 ggtgatcgcg gctgtggtgg caggggtggc agtcgcgaca tggacgctgc cccttgtccc
     2821 ggacccgtcc gtattgccgc tggccggtgc cgctgcgttc tggacgcttc cggtgctggg
     2881 cgcggccgtt gtgggcggct atccacggct ggtggagaat cgacggcgcc ggctggtcat
     2941 cgagacccgg cgctcccagc agctcgaact cgcccaagat ctgcatgact tcgtcgccca
     3001 tgacatcagc ggcatcgtcg cgcaggcaca ggccgcccgc ttcgtggccg aatccgaccc
     3061 gggtcaggcc ctgccggcac tggaacgcat cgaacgagcc ggcctgaacg ccttggcgtc
     3121 catggaccgc accgtacgca tgctccacga ggcacacggc aacggcatca gccgcccgga
     3181 cgcgcccaca ccgccgcagg cccgcccagc aacagatgac cccaggccat cagaggccca
     3241 ccaaccacct cctgcctccc aaacacctga cgccctcaac tcaccacccg ccgccccacc
     3301 gccccagcag gcccccacac tccccgcccc acccctggat tccacgcccc accccgagcc
     3361 cctaccaggc gtagcccaac tccccaccct catcgcacgc ttcacctccg ccggagccac
     3421 cgaggctcgc ctcaccatgc cgcccaccac ccccgaaacc ctctcccgcg agaccagctc
     3481 caccgcctac cggatggtcg tggaggccct caccaacgtc cgccgccacg ccccgggatc
     3541 agcccgcgtc gaggtgaccc tcaccccagc caccggcagc gacctcaccg cccacccccg
     3601 ggtgcccacc ctcgaaatcc agatcaccaa cgacgccgga accgctcccg ccaccgccct
     3661 ccgcgcccga cggcaacgcg ccggccacgg cggccgcggc ctggcctccc tgcgcgcacg
     3721 cgtccaggcg accggcggaa ccctcaccta cggcccgcac gacggcggtt ggcggctacg
     3781 ggccgtactc ccgcagaccc acccgctccc cccggagacg acatgagcgg cacccccacc
     3841 cgcatcctcc tggccgacga ccaggacgac gtccgcagcg gcttccggct cgtcctcgac
     3901 tcgcagccgg acatgaccgt catcggcgag gccgcggacg gcgccaccgc cctcgaactg
     3961 gcccgccacc tgcggccgga cgtcgtcctg gcggacatcc gcatgccccg cctcgacggg
     4021 ctggaactca cccgcctgct cgccgggccc gagtcccccc ggccgaccaa ggtggtcgtc
     4081 gtcaccacct tcgacctcga cgactacgtc cacaccgccc tgcaccacgg cgcctgcggc
     4141 ttcctgctca aacgctccgg cccgaacctg ctgatcgagg gcgtccgcgc agccatggcg
     4201 ggcgacgcgc tgatcagccc ccagatcacc gtacgactcc tccgccggct ctccccgccg
     4261 ccgccctcgc acccccaccc ccaccccggc cccggcccgg acgccctcac ggaccgcgaa
     4321 cgcgacatcg cccgcctggt ggcccgaggc ctcaccaacc aggaaatcgc caccgaactc
     4381 gtcatctcag cgggcacggc caagacccat ctcgccaaca tccaagccaa gctgaaactc
     4441 cgcaaccgcg tcgaaatcgc cgcctggtcc tggcgaaccg gcctcacccc accggcctca
     4501 tagcctcccc gcccactccg gcaagcggct gctgatcggg ccgcccaccc ccaggcagcc
     4561 tgatcgcgca cgcgttcgaa gcgaggtgag ggggttccgt tgtccctggt ttcgcgtgat
     4621 gagtgccgat gacgccgacc gatatctgct tcctggatgc caccgacctg gccgcccgga
     4681 tccggacgcg ggagctgtcc ccgctggagg tcgtccgggc gcacctcgag cgatcggcct
     4741 cggcagcgac gtcgcgatct cgatgcgcgg atcggcccac tacaccggca tcgtcgcgct
     4801 caaggcgacc cacggccgga tctctttcac cggccactgg ccggacagcc tgcgccgcta
     4861 ctggcacgtg ggcccgatgg cgcgctgtga acgccgcgcc ggctggtcgg ctgggcaggg
     4921 gtggttgacg ggtattcagg ttcggttgtc cggccggcgt ctggccggca tatggacccg
     4981 gggtgtccag tcgcaccgac ggatggtcgg catcgtgatc gcgatgccga cagctccgcc
     5041 gcgccacggg ccgctgcttc acgcgccatc cataggatcg aacatccgca tacggtccag
     5101 cactccgtcc gccgttggct gctgcagttc gtcgacgatc ctgccgtcgg cgaggaagac
     5161 cacgcggtcg gcgtaggagg cggccaccgg gtcgtgcgta accatgacga tggtctgccc
     5221 cagctgctgg accgactccc gaagcagccg cagcacctcg gcccccgccc gggaatcgag
     5281 gttcccggtg ggctcgtccg cgaagatgat ctccggctga ttcagcagcg cgcgggcgca
     5341 ggcgactcgc tgctgctgac cgccggacag ctgagggggc cggtgggcca gccgctcccg
     5401 caggcccagc gtggcgatca cttcggtgag ccattgttgg tccgggcgct tcccggcgag
     5461 ggacatcggc agcgtgatgt tctccatgac ggtgagggtc ggcagcagat ggaacgcctg
     5521 gaagatgaac ccgatccggt cccggcgcat caacgtcagc tgccggtccg acagcttggc
     5581 gagattgacc tcgccgatcc aggccgcgcc ggaggacggg gagtcgagcc cggccagaca
     5641 gtgcatcagg gtggactttc cggaacccga ggggcccatg atggccgtga agtgaccttg
     5701 gtggacgtcg aaggacacct ggtccaacgc tgttacctgg tggccgccca tgtcgtggac
     5761 cttggtgagg tcgcgggcag cggctgccgg gggatggtcc ggacggccca acggggggtg
     5821 cgacgggatc atgcgcggct cctcatctgt agttcctgac cgtcggtttc tgatcgccgg
     5881 ccctggtgcc gacccgtcgc tgtcggctcg gcgccgtcgg ttccacgggc gtcagccctg
     5941 tcggcaccgg ctccgtcggc cgtggtgtgt ccggccgtgt acgggggcga ggcgtggagg
     6001 tggcgagccg tgatggcgcc gccggcgagg gcgaggagca ccaccagcag cgcggccccc
     6061 agcacggtcg ggaagagccc gaaggcttgg gtggacacgg ccgcgagggt ggggcccagc
     6121 ggggagatgg cctgggcgag gaaaccggtc ccgctgtgca cccggccctg gagctcagcc
     6181 ggtgtcatcc ggatctgcac ggtggccagc aggacggtga ccaccggtcc acaagcggag
     6241 gcgagagcga gcaggaacgc ggcagcccag ctgtcgtgga cggtggcaaa gcccaccagc
     6301 gccacagcga tcacgccggt ggacagggcg atcccacgcg tcgctgggag acgtcgggct
     6361 gccggagcgg cgatcaggga gcctcccagg gccccggccc cgatcgccgc ggtctgcgcc
     6421 ccgatgccca gagcggcctg cgccccgccg tcggccgagg cgatgacgac gatcagcagg
     6481 ccgttgaaga ccaggttgag gacggccgcg ttgaccgccg cgtaccgcag gaacggcgag
     6541 cgccacagga agcggattcc ttcgcaggcg gccttcaacg tgggccgccc gacgccgacg
     6601 gggccggccc tcgacggcag ggccgccata cagacggccg cgacgagata cgtggcggcg
     6661 tcgagggcga agacccacac cggttgcgtg gcgagcagcg cgccgccggc cgccggcccg
     6721 gcgatcaggg tcgcggccgt ccgcgcctgg gtcaacgaca gcgccctggc gaggagatcg
     6781 gggtggacga aactccggat ggcgacgttc tcggccgggg acaacgtgct gccgaccatg
     6841 cccagaagca gcgcggcaag tgtcagcacg ggcagcgaaa gggcatcccg tgcctgaacc
     6901 aacgccagag ttaccagaat tgccgcaccg agcagattgc cgccgagcag tagcgcccgg
     6961 cggtcgaaac ggtccgcgaa caccccggca ggcagacggg ccaggagaac gcccgcggac
     7021 aacgccgtac tcgccagtcc cgcttcccgt acgtccccgg atgcctgtaa cgcgaccacc
     7081 ggcagtgcga cgatcgaggc ggacgttccg aatgccgacg cggcctcccc gccgaacaac
     7141 agccagaagg gtctgcccag cgtcggcctc gacggcactg ccatcattgc ccgctccggg
     7201 cgaactgccg ctggacggac agcagcggat gggcggtcat ggccgcggga acgccgagcg
     7261 ccaccacggc acccgccaat acaccgacgg tccatgggcc gtcgaacgtc ggcagcgggc
     7321 cgaggccgag cgtcacggac agtgggacca ggcacaccac ggcgacgagg ccggacagca
     7381 ccaccccgat cgctcccgcg ccgagtgcct cgtagagcac acagcgcagc atctggaacc
     7441 gactgaggcc cagggcccgc agatgggcgc gctgcgccac ccggtcacgc tgtgccagcg
     7501 cactggtatt ggccgccgcc aacagcgcgt acgccgcgac caccgccgct atcaggcgag
     7561 tggccagatc gtcggcggga ctgcgggtga aggtctgcgc gtagtcctcg cgtgaggcga
     7621 tggtctggcc ctttgccact ggccaggcgc tgctcggtcc ggtcaggaaa atgcggtcgg
     7681 cggtgggaga ggtggtgtgc gcgagcgcgg tggctcgcgg gagaatcatg tggggaaagg
     7741 ccaggtcgcg tgcgtagacg gcgacgaggg tgagccgctt cggcgtcgcg tcggccaggg
     7801 tcagttccac ggactggccg accttccact tcgcctggtc cgcgaattcg gcacccgcgg
     7861 cgaaggtgcc ttcgcccacc ttcgtgatgt cgccctctcg ctcggacagg ttcaccactc
     7921 gcgacagcac gcgtccgtcc actccccaag cacgggtcgg cttgggcgct gaacggcgtt
     7981 tggggccagg cacagtgacc ttggtggcta tcacaggggt ggcggtggct ccggagagcg
     8041 ggccgggcgt ggccggaagc cgggcgccgg gttccgcgct gataacagcg tcggctcgga
     8101 gcgccgcctc gacctcctgc tgggccgcgc gccccatggt ggtgccgccg cccagcagac
     8161 aggcggtgac tcctgcggac aacaggacgg gaacggccag ggccgtggtg cgcgcgggcg
     8221 ttgcccgcag gccggcagcg gcgatggtgc ccacgcgccg gtccagcacg cgcaggacgg
     8281 cgcacaccgg gcccgtcaac ggcgggatga cccacggggc cagcacggcc agggtgggga
     8341 tgacgaagag cgccagtccg ggggcgacac cggcgcgtac cttcggaggc agccccggga
     8401 ctgccatgac gaccagcagc ggggcgcaga acagtgccgc catggacaga ccggtgatca
     8461 gccgggcccg gctgcgcttg gtccccggcc caccctcgtg gtccttgagg agatcgatcg
     8521 cgttgacccg cccggcggcc cgcacgctca gcagcgcggc gagcacgctg atgacaacgg
     8581 ttcccaggca cacggcgacg caggcacccc aggtctgggc gggcggcggc agttcggtgg
     8641 cggcggggaa taacttctgt tcgatgagga tgcggcgtcc gagtcctgcc agcggcagtg
     8701 ctccggccgc ggtgccgaag gccgccgaga cgagggccag gcgcgccacg tccacggccg
     8761 ccatacgccg cagccgtgcg gcggtcatcc ccagggccct gaggacggcg aactgccgca
     8821 gccgctgtcc ggtccacagc gaaacggtgg agccgatgac cagtaccgcg cacatcagca
     8881 gcagggacat cagcagtgcc atgatgtcct gggtgctctt ggcggcggcc gcttcgggag
     8941 agtccgccgg gtgatcggca aggctcgcgc ccagcagcag gagcaggcag gccccgacac
     9001 ccgccgcggt ggcgcagcat gctgtcgccg cgccgatgac ccgcccggga taagcccgta
     9061 tctccgacaa gaggaggcgg gtcggggtgg cacgggtgat ggtcagtggg ggcggggtgg
     9121 ggagcgctgc agacacggat tcctgtcctc cacggggcga tacgctggag acggtgcggg
     9181 gaggccaccc tcatcgtggc ctccccgcac tggtctctca tggatgagag ctannnnnnn
     9241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9901 nnnnnnnnnn nnnnnnnnnn cgcgagaacg ttcgtcatgg tcggtcacct cctttcagac
     9961 agtcggtgat tgggggccgg cgggccgctc cggccggggc tcacccctgg tcagggtgag
    10021 ccccggggag caggcgggcg ccgggggtct tggctgcctc cattgccagc aggacaccag
    10081 cggatccggt ggccaagtct attgacaggc gcaggagttg gtcaccgaaa agagcttgtc
    10141 ccccgtcgtg atcagccaca tgcagtgaca ggaggcgtag ctggttctcg gcccacgagc
    10201 gcgcttgccg gatgtgagcc gcggcgtggg agaggaagta gatgttcccg gctcggccgt
    10261 tgaacagacc gccttgggac acggtgtgga ccgctgtggc gtgcgccgcc cctgccacga
    10321 tgtcgtaggc gccgatcgcg gcagcctggg tctcgggtag cgccatggcc gccagggcga
    10381 ctccgcccga gccctcggcc aggtagggga gcagccgatg ggaactgctc atctggagtg
    10441 ttccgtccaa ctgccgtgcg tgcttgaggt cggctcgtac ggcggtcgcg gcggcctcgg
    10501 cccactcctc gtcgccggtc agccgggcgc agcgggcgag cagaacggcc ggcccggacc
    10561 agccgtacat cagtccgggg cggtccagca ctccgtcgtc gccaatgcgt gcacggatgg
    10621 ccgcggccag cttgagtgct tcgtcgcgca tgccggcgtc caagaggagg tgggcgatgc
    10681 cggtcaggcc attgaacagc ccgggagagg agggaagtcg gctggagagg atgcggtcga
    10741 tgagctcctc gcccagtggg ttgccgaggc ggtgcagcag ccatgccgtg ccggccagcc
    10801 cgtcgtacag cccgagcggg gtgcgggccg gggcccggcg ggctgcgtgc tccaaccacg
    10861 tgaggtgttc ggggtccacg gaggatcctg cgctcagctg ggccaggagg accccaggag
    10921 ttccgtacgc aagtcccagc gtcgcgcctt cccgatgccc ggcgatgtcg ccggggaaga
    10981 ggcggtcgat gcgagtggtg tcggcggact tgctgatacc tcgcagcagg ggggcggcgc
    11041 gcggaggcgc gagcgggggc accgcgtcgg cccggtgtcc gggaaggtgg ggacgcacgt
    11101 tcggggacag cgccaggcgc tttgccgtcc gctcgacgta cgccgcaggc agtgtcggga
    11161 aggcggtggt ggccatctcg atcaggtggc cgatgacctc tggagtgcgc tgcaccaggc
    11221 cggtgagcgg catgaacacg gtgagttggc aacagcccag ggagtagaga tcactgtcgc
    11281 gggcgttggt gagcgacagg tcgatgaaac cgggggcgcc gagcacggtg gtgcgcttgg
    11341 tgtcaacagc cgtggcgatc tcgaagtcca ccagggcgac ggtgccgtcg tcacggatga
    11401 ggatgttgtg cgggtgaagg tcaccgaagg ccatccctgc cttgtgcagg gtctcgatgg
    11461 cggcctccgc ctgcccgagg tagtcaaggg cccgtgcggt gtactcggcg cgtgcccgct
    11521 cgtccggtgc gtggcgggtg aggggatagt cacggcccat ccacgtgctg agggagtgcc
    11581 cctggatgtg ctccatggcc aggtagtgat gctcccacgc ggcgaagtac tcgatggggc
    11641 gcgggacgaa tggcaggtgg ccgacggttt tcagggccga ccattcgttg cgcagccggt
    11701 ccaccgcgtc ggcgccggcc gcgtccaggc ccgcgtgcgg ccgcgcctct ttcaggacga
    11761 cctgagtgcc gtcgggggcc ttggccaggt acacacctcc accgttggag aagtgcaggg
    11821 ccttgaggac cgtgtagccc ttgagtgtgg cggcagggtc ctcggctgct gctgcggcga
    11881 ggctggtggt gaggaagccc ggggtctcgg cccactccgg aacggtgaaa gcgggccgtc
    11941 gccggtcggg aacggcgttg ccctgcggat cgtgcagtgc cggcacccgg gagccgtcgg
    12001 gtagttcgca ccacatgagc gcgaacgccc cgtaccggac cgacaccggc cccttgttcc
    12061 agcggtggtc ggagaggatg tacgggccgg ggcggccacc gagtaccgca tcgagttcgg
    12121 tgagggcggt gtgcagctct tccgcgtcgc gcgggtagac cgtgacgacc ttgccactgg
    12181 cggcgcggtt ggcgtacttg ctgttgagta cggtcatgat gcggcggctg cgcaggaact
    12241 tccagggcag gttcaaccgt cggcacactg cccaggtctg ctcgataact tcctcggcag
    12301 tatcgggcgt ggcagtgata tgaatcttcc agccctgttg gggtaaccgt tgcccaccaa
    12361 ccggagcgag gacttcccag acgccttgcc ggctccgctt ccattcaacg gggaattccc
    12421 gcttggtcaa agagaaccgc gaggcggcat cgtcacagcg ctccaatggc tcgtaccagt
    12481 tggaatcggc aacgatatac ggcccataat tcgggtccac ttccccccca ttttcccttg
    12541 cccgtgggga gtcctcgttc aatggcgcgc tgggcgccaa gtgagctcgg actcccgtgc
    12601 ccctatcgac atagctcatg atttgggtcg gtcgtgagga tgacaacctt tttagggtca
    12661 gcttaagcgg aacgtcgaat tacgggtggt ggcgcacgca aggcatccgg ggtgcgaggg
    12721 cgcaagccac cacacgcggg agcgaagtct gccgttcgag gaccgggtgc cacgtggccg
    12781 cacagctcgc cggaatccga tccgtcgcga agcaggtggc ggccgagcgt ggtgacggtg
    12841 tgcacgacct ggctgccgct acggcgggtc gatatcagtc cggcattccg cagcgtggcg
    12901 gtgtgctggc ttaccgctgc gggggagacc cccagcttct gggcgagatc gccgttgctg
    12961 cagccgtcgc gcaaggcatg gaggaccgct gcccgggtcc tgcccaccag gccggccagg
    13021 ctctcctgcg gtcggcgggc ggcggcaggc acggacgaca ggccctcgtc cgggaataga
    13081 ccgcactggt cactgggacg gtcggggaag atcaggactg gactgccgtc cgcaatcccc
    13141 ggaggcgacg ggagcaccgc gccggagtct tgcaggaaga gtgaaggaga cagcagcagc
    13201 ccccggccgt tcggcttcag atgcgcggtg ctttcggagt cgatttccag tacgggcgcg
    13261 gcccaccgta ttcccggacc aaggctgttc agcagtacct cgattccgtc cccacacatg
    13321 atgtcccggc ggaaatcctg ggtcgaggcg agatgctcgt aaatgcgatt ccaatacggc
    13381 tgcacggcca cctggcgcat gtcttcaacg gcggctaata actgcgattg ctgcaccccg
    13441 aggataccgg agtggttcgt atccgacgtg tccgcgccgc ctaaccagtc ggacagaatc
    13501 tcccgggacc caccgcgcac cctggccagt cttcgaaccc catcaagccg ctgacctgca
    13561 tgcaggattc tcgcattgac ccttcggcgc caggtccgga agaattcact cttcgtgttg
    13621 cgcaaggcat ccacggcgaa aatcgcctca acttgctgcc cgatcgggta ggtgattctg
    13681 atacgtgcca ggtcgtcggc gcaaagggtt atgtgttgca tgagtggcga ctccgtcctt
    13741 ccttgtggga atgaagtgga aaaaaggcgg gaaaaggttt tctttaactc cgccgaaggg
    13801 gcgcgggtgg cgcgccacta gtctttgtgt catgtcgctg aggtcaaggc ggaaaggctc
    13861 catgtggacg cgaacctgca cctgatgtgt tttctcgccg catgttggcc gcgagaaagc
    13921 cgaaaagggg aggtcgctat cgcggctggc cgggctcggc tgaatctgcc agaaaggttg
    13981 cctcgggcgt cgcgttggtt ccccgtaatg cgcgtagctc tatcccgttt gcccccgtgc
    14041 cctcctgttc ggaagagctt tacctgagtc ttgaatgctt ccacaggagc aatgtggtgg
    14101 tcggcgccat gaggaaagaa gagcctgatc tgatgtgacc taaaatggcg tgtgtcaagg
    14161 atgcctgaaa gatgcttgca agcccatgag gcggagcgga atgctccagt tcagtcactg
    14221 cttgcccgca ttacccagag tgatcaaacc gtttcgaagt ctttctttcg tgccctcttg
    14281 ggctggggtg cgttcaagcc acgcgttcag ggggtgtcat tgggtgtgtg cggtcaaggt
    14341 ggctcgaaat tcgtttcagc cgcatggatc atgcctgcgt tggcttgaag gtgcacattc
    14401 gctgggcgtg tgggctggct tgccgtaagc tccgccgttt ggatctgccg cggactggaa
    14461 tggactggcc cttggctgta cttggacctg gggctggaca ccctcgaccc ttcccagacc
    14521 cgatgccact cgtgactggc cccggtccgg gctgcgggaa aaccgccgta cagcgtgcga
    14581 agtaatctcc cggcggcaaa ccggtgttga ggctgcatgc cgacggttca tggtcccgta
    14641 cccgccgagc ccggcgaacg ctccgccacc gtgcaccagg gcggctctcg tcgcctgtgg
    14701 gccacgctcg acgagatggt ggcgttggct cgagcacggc gaactacccg tctacgggcc
    14761 gagggtgagc atcacgatgg tgaacggatg ggaggtatgc gaggacgacc ccaaggcgta
    14821 cggggagatc gggtttccac cggttcagct ccacgatctg cgccacagtg ccgcgacgct
    14881 ggcccacgcc gccggggccg agctgaaggt cattcagcaa tgctcggcca cgcctcgatc
    14941 gccatcacgg ttcaccacct acacgagcct gctgcccgag gcggatctgg tgatcgccga
    15001 ggctgcggtc cggtcgtgcc gcgcgcacgc gccacctccg agaacaccgc acccgaagcg
    15061 gagtctgaac ccggatggtg ctgatatcca tcgggagaaa tatcggggtc tggcgacccg
    15121 tccgctcatg caccgctcac gcaaacggcc ccggacgagg agtccgaggc cgactagagc
    15181 gcctccctgg gagaacccag gtcagagcgg taatgcatgg tgcccccggc aggattcgaa
    15241 cctgcgacac ccgctttagg agagcggtgc tctatcccct gagctacgga ggcatgggat
    15301 gggacccctg acagggtagc tgatgccttc gctggagatt gcttgtgtgg gggagagcgg
    15361 ggtggtgggc gtggcccggg ggcggtggtg gtgggggcac cgccgtcggg ggtcagccgc
    15421 cgatgtgcca gctgactgtg ccgtccgtgg tggcgaggag ggcgaggatg aggaggtcgg
    15481 tggcgccgag ggtgaggccg aggagggcgc ggccgcggcg ggtggtgccg cgggtcaggg
    15541 ccagggtgcc gaggaccagg gcgcaggggc cgaggaggag gttgaggacc agggtgccga
    15601 gcaggccgag gacgaaggag gccacggcca tgccgtccgc gtggcggcgg aggcgggagg
    15661 tggccgggtc gtcggcctgg gtcggttcgg tggtccgggc cggcttggcc ggagtggtcc
    15721 gtatggcttc gctgagcgtg gtcatcggga ggtcacctcg tcgttgtggc ggcgttcgcg
    15781 gaggaagaag acgagcagcc agccggcgat gacggcggcc gcgacgaggg tgaccgggac
    15841 ggggaggtgt gccgcggtgc ccagcaggat ccccatcagg aggagggctg cgacgaggaa
    15901 gagcatgatc ttcctttccg attccagagg acagttgttc actcagttcc ttcagtctac
    15961 gactgccacc gggtggagta gttcagagaa cggttgttta ctggatgaca tgagtcacag
    16021 tcttggggtc cggcaggccc agaaacagaa gacccgtcag gcgttgctcg acgcggcgct
    16081 cgggctgctg gaggagcaga gcctgagcag cctggggctg cgggaggtca cgcggtcggt
    16141 gggggtcgcc ccgaccgcgt tctaccggca cttccgggac atgggggagc tgggcgtcgc
    16201 cctggtcgag gaggcgttgg ggagtctgca tgtgatggtg cgggcgatcc tcgccgagca
    16261 ggacggggcc gaggagcgga tcgaccgtac ggtcgcggtc gtccagcagc atgtgcgcca
    16321 ccatccgctg cacatccggt tcgtggcgcg cgagcggcat ggcggggtgc gggatgtgcg
    16381 gctggccatc gcgggggagc tggaccggtt cgcggaggag gtcgcggcgg cgctcaagtc
    16441 ccagccggtg tcggaggggt ggcgcgatga cgatgtgcgg atgctggccg agttgtatgt
    16501 ggaccggttg gtgacgacgg ccgcggcgct gctcgatgcc gaggcggacg gtgcggaggg
    16561 ggcggccgag caggtcgtac gggtggcgcg gcgtcagctg cggctgatca gcgtcggacg
    16621 gcggcactgg ctggcggagg ggagggggaa gggggacacc ccctaggcgc gtgccggggt
    16681 cacccgtacg cgataggtgc cgtccgggtt ttccgtcagg accgtgacgg ccgcgccggt
    16741 ggtgcggtcg gtgtaggtgt cgccggggcg gaaggtggcg tcggtcagtt ccgggtcgac
    16801 gtatttgttg tcccggtagc agccgccgct gtgcggggtg gcgtccacga tgcggagggg
    16861 gccgcggccc gaggggacgt gggtggcgac gcggtagatg aggatgccgg ggcggcagac
    16921 cgtcgggtcc agcaggccgc gggtgcgggc ctcggccacc agggcggtgt gcggggaggt
    16981 cgggatgacg acgatctttg tgccgccgcg ggcggagacc ggggtgaggg tgtgttcgcc
    17041 gggtgtcccg cggtgaggga cgcagtgcac ctgatcggcg gagagccagc cgagtttcca
    17101 cttgtgccag ccgacgaagt cattgctcgg cccccagtcc tcgtccatcg gatcccagtg
    17161 ccctgcgggg ggcggggcgt cgcggccgtc cgtgaagtag aggtcgggca ggccgaagct
    17221 gtgggcgttc tcgtggttga ggacgcggaa ggcgctcgcc ccggtttgcc ggctccagat
    17281 gaacgatgca ttccggaacg gcaccccgtc ggcggtccgc agtcccatgt cgccaccgct
    17341 gaaggtgacc gaaaggaccg tacgggtggc gggcggcccc gcgttggggg tcgcgatgat
    17401 gttgatgacg tcgtagtcgc ggaagtcgac gagggggtcg acggcgcgta cgacttcccg
    17461 ggagagggcg tggtagccgc cgtccgaggc cgggtcgaag ccggcgccgc gctggatgcc
    17521 gtacgccgcg agcggccggg acatacggat ccatcggagc agcggcctgg ggcggtaggt
    17581 cagcctgccg tacgagctgg tgcggaagta gtccgtcgcg gccgggaaga actcggcgaa
    17641 gcggtcgcgg ggggacatcg tggcgcgggc gtccgggaag tcgatgaaga gggtcagtgc
    17701 ctccacggtg ccggacgagc gggagaaacc ggcgggggtc tcggcggatt cggcgacgtc
    17761 gtcgctgatg ccgcgcagcg cacacgggcc gctcggcggg gcgccgggca ccgagggtat
    17821 ggccacggcg ctgggcggtg agcccagggc tatcgccgcg gcggcggtgg ccgcgcctgc
    17881 ggccaggacc gcggagacct tgtgcttcat atcgatcacc ttgtgtcggc gggtgatcgc
    17941 tcgcgcgcgg gattacgtca actggagtca tggcggggtc gggtgggcag ccgcggcggg
    18001 ccggggtgtg gttcaggtca cacgagggcg tgaaatatcc ggggagggtg tccccgttta
    18061 accaggcgtc cgggtgaaac ggggagcctg tccccggttc gtgcgggtcg tcgagaccgc
    18121 accaggaccc agccgtcgga tgcgccgaca gaggagagga gtgagccgcc gtgaccgccg
    18181 ccgcacgcgt gaagtccggg aagcaggagc agcagccccg gctgcgggcc gatgcgctgc
    18241 gcaaccggga gcggatcatc gcggccgccc gcgagacgat ggtcgagttc ggggccgagg
    18301 tcccgctcga tgagatcgcc cggcgcgcgg gtgtcggtaa tgcgacgctc tatcgtcact
    18361 tcgcggatcg cctggagttg atccaccacg tcacgctgtc cgtcatgtcc cgtaccgcgg
    18421 accgcgcgga gagcgccctt gccgaggagt ccgatgcctt ccaggcgctg aggcgcttcg
    18481 tccacgccgc ggtggaggag cggatcgggg cgctgtgccc gctgctcgcc gatggcgtcg
    18541 accgggacca ccccgatctg tgcgcggcgc gggaccggct ggaggcggcc gtcgaggccg
    18601 tcatggccgc cgcacgcgac agcggccggc tgcgcaccga catcgccgtc ggtgatctga
    18661 tggtcgcgat cacccagctc acccggccgc tgccgggcag ccgctgtccg gacttcgacc
    18721 agttcgtgca ccggcatctg caactgttcc tggacggtct ccaggcaccc gcccgctccg
    18781 aactcccagg cgccgccgcc actttggatg acttgaggcg ccgctcgtaa ccccggcggt
    18841 cgccgcaccg ccgaccgtca ctccgtcccg tccttcgctc cctttcgctc actgcaccag
    18901 taggtggatc ccgccatgcc tgaaaccgtc ccgtccgtcg atccccggcg ctggaaagcg
    18961 ctgatattca tcgctctcgc ccagctgatg gtcgtgctcg acgcgaccat cgtgaacatc
    19021 gcgctgccct ccgcccagca ggatctcggt atcaccgacg ccaaccggca gtgggtgatc
    19081 accgcctacg cactggcctt cggcgggctg ctgctcttcg gcgggcgcgt cgccgacctg
    19141 tggggacgga agcggacctt catcatcggg ctcgtcggat tcgcggtcgc ctccgcgctc
    19201 ggcggggccg cggccaacca ggggatgctg ctgggtgcgc gtgccctcca gggcgtcttc
    19261 ggtgcgctgc tggcgccggc cgcgctgtca ctgctcgcgg tgaccttcac cgaggccaag
    19321 gagcgggcca aggcgttcgg catcttcggt gcgatcgccg gtggcggcgg cgccgtgggg
    19381 ctgatcctcg gcggggtgct gaccgagtac ctgaactggc gctggacctt cttcgtcaac
    19441 atcccgttcg ccgtggtcgc cgcgaccggc gccttcctgg tcatccgtga gcccgcggag
    19501 ggccgtaacc cgtcccggct ggacatcccc ggcgtcatcc tggccaccct cggcctggtc
    19561 tcgctggtct acgggttcac ccgcgccgag tcggacggct ggctcgccgg gccgacgctc
    19621 ggcctgttcg ccgcggcggc cgtgctcctg ctggcgttcg tgctggtcga agccagggtg
    19681 aaggccccgc tgctgccgct gcgggtgctc accgaccgga accgtgccgg tgtctacgcc
    19741 tcgctgggcc tggccgtgat cggcatgttc ggtctgttcc tcttcctgac gtactacctc
    19801 cagatcgtga agggctacac gccggtcacc accggtctgg ccttcctccc gatgatcgtc
    19861 ggcatggtca ccggctccac gcagatcggc gcccggctga tgacccgcgt ccggccgcgg
    19921 ctgctgatgg cgcccggctt cacggtcgcc gcactcggca tgctggtgct gacccggatc
    19981 gacctggaca cgtcctaccc cgcactgatc ctgcccggct tcctgctgat gggcctgggc
    20041 atgggcacgg cattcatgcc ggccatgtcg ctggccacac acggtgtcca gccgcgcgac
    20101 gccggtgtcg cctccgcgat ggtcaacacc tcgcagcagg tgggcggggc gatcggcacg
    20161 gccctgctga acaccatcgc ggccagtgcc accaccgcgt acgccacctc gcacgcggcc
    20221 ggtgcgcact cggccgacct gctcaagctc caggcgatgg tccacggcta caccaccgcc
    20281 atctggtggg cggtcggcat cctggccctg gcgggcgtga tcgccttcac cttcatcaac
    20341 accgggcggc cgggcgccgg ttcgccggcg gcctcctcgg ccgaggagga gcgcacggtc
    20401 ctgggctcgt cggagggccg ggacgagatc caggtgccgg tcatggcgca ctgagcggac
    20461 ggctacgggc cggaccgtac ggcgtcccgc ggggggcggg cccggccgtg gccggcccgc
    20521 cccggcctcg gggcgctgcg agcgccgcac ctgcgccgtc cttgcccggc ccttcgctca
    20581 cacgggcgtc ggcctctccc ggctccgctg atccgtcagc gcagccaggg gaggtcggcg
    20641 cctttcggtt gcagcccttc ggtcatcact tggcagatct cggcgagttg gccgacctgc
    20701 tccggggaga ggcggtcgaa gatcgcggag cgtacggcgg cgacatgtcc gggggcggcc
    20761 ttctccagga cccgcatccc ctcatccgtg agaagggcgt tctggccccg cttgtcggaa
    20821 gggcagttct cgcgccgtac ccagccgttc ttctccaggc gcgcgaccgc atgcgagagc
    20881 cgggagcggg tgatcttggc gttctgagcc agctcggtca tccgcatccg gcgccgcggt
    20941 gcccgggaga gctggacgag caggccgtaa tagacgtgcg gcatccccgc gtcccgttgc
    21001 agctggcggt cgaggtggtc ctccaggagc gtggtggcgt ggaggtagca ctgccaagcg
    21061 aattgctcct cgtcgctgag ccagcgcggc tcggctgcgg gttcgttgct cataccatcc
    21121 actctctcac cactcggaga gttatttaag ttttaacaac gtccaattgt gcccaaatcc
    21181 tgacacttga aacttcaagt atgtggttct gttgatgctg cgatcctctg catccactac
    21241 tgccaagtgt gaccccgtga agcagtgatg tccgtaacgg gcggccgacg atctgtccgg
    21301 cacaacggtc cgtccgtcag tcggccttgt cgatcagtgc catggcgttc agggcggccg
    21361 acagggcgcg ggagtcaccg tcctcggagg ccgccgcgac gtccagagcg gtgtcggcga
    21421 acttgatcgc atgctcgtcg ccgtgggtga ccgcccgctc gaagacctcc tcgggtgcga
    21481 gtcccgcggc gctcggtgcc gggcgcgcgg tgtccgcggc gtagagcgtg gtgagcgcgg
    21541 aggccgccgc ccaggccacc gcgaacgagc ccgcccagag ctcccggggg agcgcgggca
    21601 gggtgcgcag caccgcgttg ggcgcggtgg cggcgtgtac cagcaggatg ccgtgcccat
    21661 gaccgtggtc cgcgtagttg agggtggcgg cccgcacgag cgcggtcagg ccctcgcggg
    21721 cggcttcggg gtcctcgggg atgtgcagcg attcggtggt gctcaaccag ccggatatgt
    21781 gcgggagttg ggcgtagccg ttcaggggca tcacgttccg ctcggtgata cgggggaggg
    21841 cggccagggc ctcggccggg gtggcgccgc cctgggggcg cacggtggtg ggcagaagca
    21901 gatggcgggc ggcccagtag ccgagggcgt gcgcgagctc cgcgatccgg gcctcgtcct
    21961 ccccttccgt cagcaggctg cgtacggcat ggcccacgcg gatgacgggg tgggtggcgg
    22021 cgccggcgat gccgggcagc agccgcggcc accactcggc gagcagcgca cgccaggggc
    22081 gctcggcgat ctgctcggtg aagtagccgg tccagtcggt gacccggccc ggatcgccca
    22141 gtgcctgctg ccagttggtg tcggtgatac ggccttgggg agccggtacg tcctccagct
    22201 tccgcgcgta ggtgtcgagc cagcggtgga cggtccgggc ctggccgttg cggaccatgg
    22261 cttcgacggc catcgggccg tggttgctca gatagccccc gaactcgggg ccggcggtgt
    22321 gcaggcgtaa cagggcttcg tcgagggtgc ggttcgtcgt ctccatggcc cgaggctagg
    22381 tcggcgcgaa ggcgtcccgt atcgggcttc cggcccacac cgctggtctt cgcggcctac
    22441 gccgccggcc tccacggctt acggcgccgg tcgtaaggcc gctgctgggg gcggtcgcgg
    22501 gggagacgcc ggtgccgcgg tgcgtcggtg tcccgagccc ggtgtcccga gtccgttgtt
    22561 ccggctcctg gggcccgcag ccaaaccgga caggagatgt cgggtattgg ggggagggt
//
