LOCUS       NZ_BBNO01000003        36111 bp    DNA     linear   CON 19-AUG-2024
DEFINITION  Streptomyces lydicamycinicus strain TP-A0598, whole genome shotgun
            sequence.
ACCESSION   NZ_BBNO01000003
VERSION     NZ_BBNO01000003.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces lydicamycinicus
  ORGANISM  Streptomyces lydicamycinicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Komaki,H., Hosoyama,A., Igarashi,Y. and Tamura,T.
  TITLE     Streptomyces lydicamycinicus sp. nov. and Its Secondary Metabolite
            Biosynthetic Gene Clusters for Polyketide and Nonribosomal Peptide
            Compounds
  JOURNAL   Microorganisms 8 (3), 370 (2020)
   PUBMED   32155704
  REMARK    DOI:10.3390/microorganisms8030370 Publication Status: Online-Only
REFERENCE   2
  AUTHORS   Komaki,H., Ichikawa,N., Hosoyama,A., Fujita,N. and Igarashi,Y.
  TITLE     Draft genome sequence of marine-derived Streptomyces sp. TP-A0598, a
            producer of anti-MRSA antibiotic lydicamycins
  JOURNAL   Stand Genomic Sci 10, 58 (2015)
   PUBMED   26380643
  REMARK    DOI:10.1186/s40793-015-0046-5 Publication Status: Online-Only
REFERENCE   3  (bases 1 to 944465)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: Newbler v. 2.6
            Genome Coverage                   :: 93x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000829715.2-RS_2024_08_19
            Annotation Date                   :: 08/19/2024 02:08:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,323
            CDSs (total)                      :: 7,237
            Genes (coding)                    :: 7,092
            CDSs (with protein)               :: 7,092
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 54 of 145
            Pseudo Genes (incomplete)         :: 123 of 145
            Pseudo Genes (internal stop)      :: 9 of 145
            Pseudo Genes (multiple problems)  :: 39 of 145
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:07:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 345705
            Orig. end                         :: 381816
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBNO01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..36111
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAPAA"
                     /region_number="4"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..36111
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..36111
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[15000:21111](-)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(15001..21111)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     gene            56..976
                     /locus_tag="TU31_RS10470"
                     /old_locus_tag="TPA0598_03_02590"
     CDS             56..976
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TU31_RS10470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TPA0598_03_02590"
                     /product="hypothetical protein"
                     /protein_id="WP_052718879.1"
                     /transl_table=11
                     /translation="MEPRELWERHAVLAQAFCSSDDEVRRTQGLLDEAEARRSRTLAAF
                     AVTVGSDAVVADLLGLEEREVRLARRTVGKEDARAVAKSLLAQPPCEPAPAPQQPAPQA
                     PAAQAPAPQPPQGAAAPGPVAPPPQQGPAAAPQPSEPAWAPALDAVLMSSWHNGVDLTA
                     LATELGLDVRLLVARAQQLSAESRPMPPTPSDRTGRHRRLVNVPPPQPETPHLTWRERP
                     QQPPREHYEQEHWKQQPYQHYPDQQQYQEYRVYEEHQQYQQPTQPTWDANAITAAQHDW
                     DGILSQWEATAAPQPPLSAPGQGGG"
     regulatory      1102..1190
                     /bound_moiety="5-aminoimidazole-4-carboxamide
                     ribonucleotide (ZMP)/
                     5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl
                     5'-triphosphate (ZMT)"
                     /db_xref="RFAM:RF01750"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01750"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ZMP/ZTP riboswitches appear to regulate genes
                     involved in one-carbon metabolism; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    1142..1156
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            1212..2066
                     /locus_tag="TU31_RS10475"
                     /old_locus_tag="TPA0598_03_02600"
     CDS             1212..2066
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572286.1"
                     /locus_tag="TU31_RS10475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02600"
                     /product="bifunctional 5,10-methylenetetrahydrofolate
                     dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_042152571.1"
                     /transl_table=11
                     /translation="MSPDARLMDGSALARSMVEKAARRAADLTERTGTAPCLATVLVGD
                     DPASVTYVRMKRNRCAKAGILSRHVALPAATTTAELVDTITALSNDPAVHGILLQHPAG
                     PHIDERAAFEAIAPEKDVDGVTCHSFAAMSFGLDGFASCTPGGILRLLDHYDVDLAGKH
                     AVVVGRSAILGKPVGMLLLGRNATVTYCHSRTTDLASLTREADVLIAAVGRPRFLGGEH
                     IKPGAVVMDAGSNPGNVGDVDFDAARTRAALITPVPGGVGPMTIATLLTQTVDAASAQL
                     NAV"
     gene            complement(2157..3278)
                     /locus_tag="TU31_RS10480"
                     /old_locus_tag="TPA0598_03_02610"
     CDS             complement(2157..3278)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014626845.1"
                     /locus_tag="TU31_RS10480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02610"
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="WP_042152575.1"
                     /transl_table=11
                     /translation="MTASAAATRAAQTLSRPFALGGRTVPNRIAMAPMTREFSPGGVPG
                     ADVADYYARRAAGGVGLIITEGTYVGHPAAGTSGAVPRFHGADALDGWSRVVESVHAAG
                     GTIMPQLWHVGMARKAGAPPFPDAPPSGPSGIALDGTPSGHAMTQRDLDEVIAAFAEAA
                     ATAERLGFDGVELHGAHGYLIDQFLWSGTNRRTDAYGGSRTARTRFAAEIVAACRAAVS
                     PGFPVLFRMSQWKMGNYEARLAETPEELQEIVAPLTDAGVTAFHCSTRRYWLPEYEGSD
                     LNLAGWVKKLSGRPTLTVGSVGLDNEFIGTFQGEQAGVSGIDRLLDRLERDEFDLVAIG
                     RALLGDPEWAAKILEGRTDALVPFDASMLRTLN"
     misc_feature    3274..3289
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            complement(3500..4672)
                     /locus_tag="TU31_RS10485"
                     /old_locus_tag="TPA0598_03_02620"
     CDS             complement(3500..4672)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541024.1"
                     /locus_tag="TU31_RS10485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02620"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_042152577.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.2e-55, bitscore:
                     183.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSVAVIGASLAGLYAARALRAQGFDGRLVIVGEEHHRPYDRPPL
                     SKGFLTGATADLGQLALADAEETAELDAEWRLGTRATGLDTHGRAVLLDGGRSLTTDGV
                     VIATGATPRRLPGPAPAGTHTLRTLEDAQALRAELTRGPVRVVVIGGGFIGAEVASSCA
                     ALGHDVTVVEAAPLPLVPQLGEAMAGICSTLHADHGVTLLTGTGVARLHDGGTGNRVSA
                     VELTDGRLLPAEVVVIGIGVRPHTAWLEGSGLPLDDGVCCDAGGATPQPHIVAVGDVAR
                     ADGTRAEHWTSATEQAAVAVRNLLAGRTVAAHRSLPYFWSDQYGVRIQFAGRRLPTDTP
                     RIVEGSPDDRSFLACYERDGRTTAVLALNRPRPFMRLRRELARAAQPVTT"
     gene            complement(4669..4992)
                     /locus_tag="TU31_RS10490"
                     /old_locus_tag="TPA0598_03_02630"
     CDS             complement(4669..4992)
                     /EC_number="1.14.12.19"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541025.1"
                     /locus_tag="TU31_RS10490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02630"
                     /product="bifunctional 3-phenylpropionate/cinnamic acid
                     dioxygenase ferredoxin subunit"
                     /protein_id="WP_042152581.1"
                     /transl_table=11
                     /translation="MIPVCPLADLPTGESVRIDTAPPIAVFHADGQLYAIDDTCTHQDA
                     SLSDGWLEGCLVECPLHAASFDLRTGAATCLPARRAVRTHPVTVEDGMIYVHHHAAEEG
                     TAA"
     gene            5161..5961
                     /locus_tag="TU31_RS10495"
                     /old_locus_tag="TPA0598_03_02640"
     CDS             5161..5961
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016909427.1"
                     /locus_tag="TU31_RS10495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02640"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_181018581.1"
                     /transl_table=11
                     /translation="MTDSVEGRAEAKPPKQPGGVQSVDRAVTVLEILARHGEAAVTEIA
                     EELGVHKSTAFRLLGVLENRGLVGQEQERGKYYLAAGVLRLAGAAAVRLDISQEGAPVC
                     RQLAEELGETVNIAVLESDAAVNVTQARGPASVTAQNWLGRRTPLHATSSGKALLAYQP
                     RAVQEAVLARKLPRLTERTVTSAAALRRELAEVVERGFAVAIEELELGLRAVAAPVRGP
                     DGSVIGAISVSVPAYRLAEERLPEVVKATVSAAEELSRRMGYGR"
     gene            6151..7236
                     /locus_tag="TU31_RS10500"
                     /old_locus_tag="TPA0598_03_02650"
     CDS             6151..7236
                     /EC_number="1.1.1.306"
                     /GO_function="GO:0050607 - mycothiol-dependent formaldehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0010127 - mycothiol-dependent
                     detoxification [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (24-280). E-value: 4.1e-11.
                     Score: 34.5. Matches aSDomain:
                     nrpspksdomains_TU31_RS10500_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541027.1"
                     /locus_tag="TU31_RS10500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02650"
                     /product="S-(hydroxymethyl)mycothiol dehydrogenase"
                     /protein_id="WP_042152584.1"
                     /sec_met_domain="ADH_N (E-value: 4.7e-29, bitscore: 96.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 7.1e-28, bitscore:
                     92.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHHVHAVVAAKQGAPVEPQTILVPDPGPGEVLVTVQACGVCHTD
                     LHYREGAINDQFPFLLGHEAAGVIESVGPGVTDLAPGDYVVLAWRAPCGSCRSCRRGRP
                     WYCFDSRNATQPMTLLDGTPLTPALGIGAFAEKTLVAAGQAVKVDPHARPEAAGLIGCG
                     VMAGYGAAVHTGGVGSGDTVAVIGCGGVGNAAIAGASIAGARRIIAIDIDDHKLDGATR
                     FGATHTVNSRGTDPIEAVRGLTGGHGADVVIDAVGRPETYTQGFYMRDLAGTLVQVGVP
                     DPGMRLELPLIDLFSRGGALKSSWYGDCLPSRDFPVLIDRYLSGRLDLDGFVTETIGLD
                     EVESAFDKMRDGRVLRSVVVL"
     aSDomain        6223..6990
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TU31_RS10500_PKS_ER.1"
                     /evalue="4.10E-11"
                     /label="TU31_RS10500_PKS_ER.1"
                     /locus_tag="TU31_RS10500"
                     /protein_end="280"
                     /protein_start="24"
                     /score="34.5"
                     /tool="antismash"
                     /translation="PDPGPGEVLVTVQACGVCHTDLHYREGAINDQFPFLLGHEAAGVI
                     ESVGPGVTDLAPGDYVVLAWRAPCGSCRSCRRGRPWYCFDSRNATQPMTLLDGTPLTPA
                     LGIGAFAEKTLVAAGQAVKVDPHARPEAAGLIGCGVMAGYGAAVHTGGVGSGDTVAVIG
                     CGGVGNAAIAGASIAGARRIIAIDIDDHKLDGATRFGATHTVNSRGTDPIEAVRGLTGG
                     HGADVVIDAVGRPETYTQGFYMRDLAGTLVQVGV"
     CDS_motif       6331..6369
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TU31_RS10500_0001"
                     /evalue="5.90E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="TU31_RS10500"
                     /protein_end="73"
                     /protein_start="60"
                     /score="9.7"
                     /tool="antismash"
                     /translation="LGHEAAGVIESVG"
     CDS_motif       6955..6987
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TU31_RS10500_0002"
                     /evalue="3.20E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="TU31_RS10500"
                     /protein_end="279"
                     /protein_start="268"
                     /score="1.5"
                     /tool="antismash"
                     /translation="RDLAGTLVQVG"
     gene            7287..9746
                     /locus_tag="TU31_RS10505"
                     /old_locus_tag="TPA0598_03_02660"
     CDS             7287..9746
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671442.1"
                     /locus_tag="TU31_RS10505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02660"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_042152586.1"
                     /sec_met_domain="DAO (E-value: 4e-54, bitscore: 180.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTPAPSSRVVVIGAGIVGCSLADELTARGWTDVTVLEQGPLPA
                     PGGSTSHAPGLVFQTGPSKTLTEFAAYTVQKFRSLDVDGLSCFNPVGGLEIATTEARWA
                     DLHRKAGLAASWGVRGELIGPQQCKRLWPMLGETTLHGGFHTPDDGLARAVLACRAQIA
                     RAESRGARFLERHTVTGIERADGRVTGVTTDRGTFPADHVVSAAGFWGPVIGAMAGVDV
                     PLLPLAHQYATTAPLPELAGVNDPRTEASKPILRFQDRDLYFREHTDRIGIGSYAHRPM
                     PVDPFTVAAFDDAPVMPSSLPFTAEDFAPSWQDSIGLLPALGSSRVAEGFNGVFSFTPD
                     GMPVLGESRELRGFWLAEAVWVTHSAGVAKAVAEWMTDGRPATDIHECDLYRFEDAQRS
                     PAYIADRGAQNFIEVYDVIHPLQPMEAPRPLRTSPFYPRQQELGAYFLEGGGWERPHWY
                     EANAPLAEGLRLPERDAWSARYWSPIAAAEARATREKVALYDMTPLRRLEVTGPGALAF
                     LQRMTSNNLAKKPGAVTYTLLLDETGGIRSDLTVARLAPDRFQVGANSGADLDWLLRHA
                     PDEGVQVRDITSGTCCIGVWGPLARALVQPLTRDDFSHQAFGYFRARQTYLGHVPVTAM
                     RLSYVGELGWELYTTADMGLRLWDTLWEAGQEHGVIAAGRSAFNSLRLEKGYRAWGHDM
                     TTEHDPYEAGVGFAVRPAKGDFIGRAALEGMTEETVSRRLTCLTLDDPAAVVLGKEPVH
                     VDGAPAGYVTSAAYGYTLGRGIAYAWLPAGAAAPGTPVHIEYFGEKIPATVAQEPLFDP
                     QMERIRR"
     gene            9810..10970
                     /gene="solA"
                     /locus_tag="TU31_RS10510"
                     /old_locus_tag="TPA0598_03_02670"
     CDS             9810..10970
                     /EC_number="1.5.3.2"
                     /GO_function="GO:0050131 - N-methyl-L-amino-acid oxidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="solA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988347.1"
                     /locus_tag="TU31_RS10510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02670"
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="WP_042152589.1"
                     /sec_met_domain="DAO (E-value: 2.4e-47, bitscore: 157.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPTYDVIVLGLGGMGSAAAHHLAARGARVLGLEKFGPVHNRGSS
                     HGGSRITRQSYFEDPAYVPLLLRSYELYEKLERDSGREIATLCGGVMLGRPDSRTVRGS
                     LESARQWDLPHEMLEPKEIRRRFPTLTPAEDEVALYEARAGLVRPEYTVAAHVQLAGQD
                     GAELHFEEPVTRWEELPGAAGVRVHTPENTYTAGQLVICPGAWAPQLLTDLGVPFTIER
                     QVMYWFAPRGGTAPFVPDRHPIYIWEDDRGVQIYGFPSIDGPDGGAKVAFFRKGTVCTP
                     ETIERTVHDHEVRAMADQLAPRLPALPGRFLKAATCMYSNTPDEHFVITRHPGHPETVT
                     VACGFSGHGFKFVPVVGEIVADLALTGTTAHPIELFDPRRPAAAAA"
     gene            10982..12151
                     /locus_tag="TU31_RS10515"
                     /old_locus_tag="TPA0598_03_02680"
     CDS             10982..12151
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541030.1"
                     /locus_tag="TU31_RS10515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02680"
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_042152592.1"
                     /transl_table=11
                     /translation="MTTTPTESSPAPTTPAPAAAPSLIATLAGHHYTDPGIFRQEQEKI
                     FERLWFCAVRSADLEKPGAFRTVRIGRESVLITRNRAGALRAFLNICRHRGAQLCTEES
                     GEVRRNLQCPYHAWTYDLDGRLVAAPNLQKMPDIDRTERGLVTVPLREWLGYAWVCLAD
                     EPPSFEDTVIGAAVERLGDAASLDRYRTEGLALGKRLTYDVRANWKLIIENFMECYHCG
                     TIHPELTEVLPEFADGFAAQYYVGHGAAFAEEATGFTVDGTDGFGRLPGIEDTQDRRYY
                     AITVRPQVFVNLVPDHVIVHRMFPMAPDRTVVECDWLYLPEVVDSGADVSKSVELFHRV
                     NAQDFDACERTQPAMSSRAYRDGGVLVPSEHHIGAFHQWVTDCLAGGSG"
     gene            12226..12768
                     /locus_tag="TU31_RS10520"
                     /old_locus_tag="TPA0598_03_02690"
     CDS             12226..12768
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TU31_RS10520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TPA0598_03_02690"
                     /product="hypothetical protein"
                     /protein_id="WP_042152595.1"
                     /transl_table=11
                     /translation="MNLSFERPAAYDLGADADLGLWLAEWAEYADRIVHLGPDDGRDHG
                     QLCWDVLAPTGLLAPHCRECRHPHGGPRRPQQMASALHRHIPPAEASPWIAATLIRSLV
                     FPGGDGPMRPVADALGDGLVELLGPDAQWRANGYAAYREGAERNVSWKPVTEATFDAAV
                     VGIGGGHAVVVVATGED"
     gene            complement(12814..13872)
                     /gene="sbnA"
                     /locus_tag="TU31_RS10525"
                     /old_locus_tag="TPA0598_03_02700"
     CDS             complement(12814..13872)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450235.1"
                     /locus_tag="TU31_RS10525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02700"
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="WP_078885682.1"
                     /sec_met_domain="PALP (E-value: 9.5e-49, bitscore: 161.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVISAPYAFNEEDLYVDLRSIFGHSLFLKCEGFNFAGSIKLKAA
                     TEMVESAERAGDLRPETVLVESSSGNLGVALSMIAASKGYRFLCVTDSRCNLATRLMME
                     ALGSQVHVVADQESNGGFLGARLAYIRNLCASDDRCLWLSQYTNPSNWKAHYRRTAPAI
                     ARAFPRLDLLFVGAGTTGTLMGCARYFREWHRPVRIVAVDSVGSVTFGGTPGHRMIPGL
                     GMSVQPPLLDESYVDDVVRVAEADTIRTCHRLAKRGFVFGGSTGTVVSGATDWLTRHDA
                     RGRTAVAIAPDLGERYLDTVYHDNWVQDLYGEDVLAAGPPLDASGLPPSGLTPPPGPLE
                     PSSRPRRRRDDG"
     gene            complement(13930..14997)
                     /gene="sbnB"
                     /locus_tag="TU31_RS10530"
                     /old_locus_tag="TPA0598_03_02710"
     CDS             complement(13930..14997)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sbnB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005319085.1"
                     /locus_tag="TU31_RS10530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02710"
                     /product="2,3-diaminopropionate biosynthesis protein SbnB"
                     /protein_id="WP_042152597.1"
                     /transl_table=11
                     /translation="MTTVRPTPSRPTPGPPPTPSFAVISGAQVQQALEGREKEIVDVVE
                     ATYRLHGAGESVNPPSSFLHLPDRPSSRIIALPASIGGETRVDGLKWISSFPPNVAAGI
                     PRASAVLILNDHDTGYPFACLESSIISATRTAASAASAADRLSRGRPRPTRVGFFGAGL
                     IARYIHTFLEGTGWSFDEIGVHDLSAESAAGFRLYLEQSRTTGRVTVHHSAEELIRASD
                     LVVFATVAPRPHVHEVSWFGHHPVVVHVSLRDLAPQILLTSTNIVDDIEHCLRAATSPH
                     LTEQLTGNREFLHGTLDDVLAGRVAVPADRTAVFSPFGLGVLDLAVGKYVYDEVVRSGE
                     LRVVDGFFHELRRYG"
     gene            complement(15001..18555)
                     /locus_tag="TU31_RS10535"
                     /old_locus_tag="TPA0598_03_02720"
     CDS             complement(15001..18555)
                     /NRPS_PKS="Domain: AMP-binding (239-643). E-value:
                     4.6e-102. Score: 333.6. Matches aSDomain:
                     nrpspksdomains_TU31_RS10535_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (751-818). E-value: 5.1e-19. Score:
                     60.2. Matches aSDomain: nrpspksdomains_TU31_RS10535_PCP.1"
                     /NRPS_PKS="Domain: TauD (884-1166). E-value: 5.6e-46.
                     Score: 149.4. Matches aSDomain:
                     nrpspksdomains_TU31_RS10535_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123298.1"
                     /locus_tag="TU31_RS10535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02720"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_042152600.1"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-109, bitscore:
                     360.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.5e-11, bitscore:
                     39.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TauD (E-value: 7.3e-45, bitscore: 149.4,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAHTRRDRGGSADGAYTRVPRWTRIPVPGTAEHTTALPEHLPAT
                     LRRLADRLRMPLSSVLLAAHAKVLAVLSGDHEVTTGYLAERGGTPLPCRLTTAAGSWRT
                     LLLDTHRAEVELLRRRGFPAAGSGPEPAPAEGDPETVFDLPGAEGGPVGDTVLWVALVR
                     HDGREVLRLRFRTEVLDADCAARIGGYYRTALALLAADPDAEHRRQSLLSAEELRCQLE
                     GLAGPSRPLPDRRFHEVFQQRVRAHPDAIAAVHGSRRWTYRELNVRANRLAHALLARGL
                     GREDVVAVVTERNLEWLAAVIAIFKAGGVYLPVEPHFPPGRIALMLSRAGCRQVLTEPG
                     STAGLDRALASVPGVRTLFIDAVCAASPADSDPEVRVGPDQLAYIYFTSGSTGEPKGAM
                     CEHLGMLNHLYAKIDDLAIDEGQVVAQTAPQCFDISLWQLLSALLVGGRTLLVEQAAVL
                     DVGRFLDTVGEGGATVLQVVPSYLDVVLSALAQRPGALPDLRCVSVTGEALKKELVQRW
                     FAARPGIHLVNAYGLTETSDDTHHEVMDGVPDTERVPLGRPVNNVRVYVVDEHLAPVPL
                     GAPGEIVFSGVCVGRGYINDPERTRLAFVPDPHRPGQRLFRAGDHGRWLPDGKLEFLGR
                     RDSQVKIRGFRIEMGEIENALLRVPGVGDGTVVVTQRAGHGKRLVAFYSGRHALEADVL
                     RGRLGELLPEYMVPSVFLWRESLPLTANGKIDKKALEALAGGLDTVEDDYHAPRTPTER
                     RLAAAWAEVLGMPRDRIGRQDNFFDCGGTSLSAVALAVSLGRAVSVRDLTRHPVLADLA
                     RQIDDRAGLPRTQPNDAARAVRCDTARPAASRAATERRTTMVSSLSISLPELEREPGTP
                     PMLRVGTTDSAAHWAAERRDALRAVVAEHGAVLIRGLGMRDPAGVGAVRHGLGVAPLTE
                     REAFALRQTYSEGVYSSSKWPPNQPMCMHHELSYTLEFPGLMLFACLGAPTTGGATGVA
                     DSAAVLDALPPALAERFEREGWLLTRSYHPEIGATLDQAFGTEDRDAVERYCRAHAIDF
                     AWQPDGGLRTTQRRSAVLHHPVSGRRCWFNQIAFLNEWTMAPEVREYLIDEYGPDGLPF
                     NTRYGNGEPLAEDVVLLLNEVYDAHTVRRPWEAGDLLLVDNVRSAHSREAFEGPRDVVV
                     ALADPVRLADCSPTVEVN"
     aSDomain        complement(15058..15903)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TU31_RS10535_TauD.1"
                     /evalue="5.60E-46"
                     /label="TU31_RS10535_TauD.1"
                     /locus_tag="TU31_RS10535"
                     /protein_end="1166"
                     /protein_start="884"
                     /score="149.4"
                     /tool="antismash"
                     /translation="WAAERRDALRAVVAEHGAVLIRGLGMRDPAGVGAVRHGLGVAPLT
                     EREAFALRQTYSEGVYSSSKWPPNQPMCMHHELSYTLEFPGLMLFACLGAPTTGGATGV
                     ADSAAVLDALPPALAERFEREGWLLTRSYHPEIGATLDQAFGTEDRDAVERYCRAHAID
                     FAWQPDGGLRTTQRRSAVLHHPVSGRRCWFNQIAFLNEWTMAPEVREYLIDEYGPDGLP
                     FNTRYGNGEPLAEDVVLLLNEVYDAHTVRRPWEAGDLLLVDNVRSAHSREAFEGPRDVV
                     V"
     aSDomain        complement(16102..16302)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TU31_RS10535_PCP.1"
                     /evalue="5.10E-19"
                     /label="TU31_RS10535_PCP.1"
                     /locus_tag="TU31_RS10535"
                     /protein_end="818"
                     /protein_start="751"
                     /score="60.2"
                     /tool="antismash"
                     /translation="ERRLAAAWAEVLGMPRDRIGRQDNFFDCGGTSLSAVALAVSLGRA
                     VSVRDLTRHPVLADLARQIDDR"
     aSModule        complement(16102..17838)
                     /complete
                     /domains="nrpspksdomains_TU31_RS10535_AMP-binding.1"
                     /domains="nrpspksdomains_TU31_RS10535_PCP.1"
                     /locus_tags="TU31_RS10535"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(16597..16662)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TU31_RS10535_0004"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="TU31_RS10535"
                     /protein_end="653"
                     /protein_start="631"
                     /score="36.0"
                     /tool="antismash"
                     /translation="FLGRRDSQVKIRGFRIEMGEIE"
     aSDomain        complement(16627..17838)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TU31_RS10535_AMP-binding.1"
                     /evalue="4.60E-102"
                     /label="TU31_RS10535_AMP-binding.1"
                     /locus_tag="TU31_RS10535"
                     /protein_end="643"
                     /protein_start="239"
                     /score="333.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FQQRVRAHPDAIAAVHGSRRWTYRELNVRANRLAHALLARGLGRE
                     DVVAVVTERNLEWLAAVIAIFKAGGVYLPVEPHFPPGRIALMLSRAGCRQVLTEPGSTA
                     GLDRALASVPGVRTLFIDAVCAASPADSDPEVRVGPDQLAYIYFTSGSTGEPKGAMCEH
                     LGMLNHLYAKIDDLAIDEGQVVAQTAPQCFDISLWQLLSALLVGGRTLLVEQAAVLDVG
                     RFLDTVGEGGATVLQVVPSYLDVVLSALAQRPGALPDLRCVSVTGEALKKELVQRWFAA
                     RPGIHLVNAYGLTETSDDTHHEVMDGVPDTERVPLGRPVNNVRVYVVDEHLAPVPLGAP
                     GEIVFSGVCVGRGYINDPERTRLAFVPDPHRPGQRLFRAGDHGRWLPDGKLEFLGRRDS
                     QVKIR"
     CDS_motif       complement(16744..16833)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TU31_RS10535_0003"
                     /evalue="1.60E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="TU31_RS10535"
                     /protein_end="604"
                     /protein_start="574"
                     /score="36.4"
                     /tool="antismash"
                     /translation="PLGAPGEIVFSGVCVGRGYINDPERTRLAF"
     CDS_motif       complement(17350..17409)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TU31_RS10535_0002"
                     /evalue="5.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="TU31_RS10535"
                     /protein_end="402"
                     /protein_start="382"
                     /score="28.2"
                     /tool="antismash"
                     /translation="AYIYFTSGSTGEPKGAMCEH"
     CDS_motif       complement(17614..17649)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TU31_RS10535_0001"
                     /evalue="2.90E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="TU31_RS10535"
                     /protein_end="314"
                     /protein_start="302"
                     /score="11.2"
                     /tool="antismash"
                     /translation="AIFKAGGVYLPV"
     gene            complement(18574..21111)
                     /locus_tag="TU31_RS10540"
                     /old_locus_tag="TPA0598_03_02730"
     CDS             complement(18574..21111)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (36-98). E-value: 1e-10.
                     Score: 33.7. Matches aSDomain:
                     nrpspksdomains_TU31_RS10540_PP-binding.1"
                     /NRPS_PKS="Domain: TIGR02353 (131-832). E-value: 1.5e-234.
                     Score: 772.2. Matches aSDomain:
                     nrpspksdomains_TU31_RS10540_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005319079.1"
                     /locus_tag="TU31_RS10540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02730"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_078885683.1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-09, bitscore:
                     34.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 2e-233, bitscore:
                     772.2, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGEPVEELTSYPEESPAGRCGADGPAPGVEAAFAVTLAEVMGTG
                     QTPVDRNFFDDLGADSLVMAHFCARVRKRADLPPVSMKDIYRYPTIRALATALAGSPPS
                     FPVETPPPAPTPPSAPAPAVRGTSRYVLCGALQLLTFLGYTSLVAVATAWGYEWIAAGS
                     GMFGRYLRSVLCGTAGLLLLCALPILVKWVLIGRWKPQQFRVWSLPYLRFWVVKTLIRA
                     NPLVLFVGSPLYTLYLRALGAKIGRGVTVFSRNVPVCTDLLALGDGTVIRKDAFLNCYR
                     AQAGLMQTGTVVLGKNVVISEATVLDIETALGDGAQLGHASSLHSGQVVPDGEHWHGSP
                     AQRTDVDYRVVGPARCGALRRTVHSALQLVTVLLLYVPLAVGGVGILLAEAPQLTAVLE
                     PGPTALGDGTFYMDALLLSLLFFAAVPLGLLFQATVPRLLSRTITPGRVYPLYGFHYAV
                     HRLIALTTNRKFLMRLFGDSSAIVHYLRGLGYDLSRIEQTGSNFGTEVKHETPYLSSVG
                     SGTMVADGLSVMNADFSDTSFRVCRTSIGPRNFLGNRIAYPSRGKTGDNCLLATKVMVP
                     VDGEVREGVGLLGSPSFEIPRSVQRDSTFDQLKSGEQLRRHLTAKNRHNAATMALYLLV
                     RWLYFFWVTLLVAVAAELYDSLGALAIALGNVLVLVSGVVYFVLVERAVTAFHPLSPLF
                     CSIYDPRFWRRERFWKVPSETYLLFFNGTPFKNLIWRLLGVRIGRRVFDDGCYLTERTL
                     AAIGDGCTLNVGSVVQCHSQEDGTFKSDRSTLGAGCTLGVGAFVHYGVAMGDGAVLAPD
                     SFLMKGEAVPPHTHWGGNPARQTCGQDTGEGWR"
     aSDomain        complement(18616..20718)
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TU31_RS10540_TIGR02353.1"
                     /evalue="1.50E-234"
                     /label="TU31_RS10540_TIGR02353.1"
                     /locus_tag="TU31_RS10540"
                     /protein_end="832"
                     /protein_start="131"
                     /score="772.2"
                     /tool="antismash"
                     /translation="LCGALQLLTFLGYTSLVAVATAWGYEWIAAGSGMFGRYLRSVLCG
                     TAGLLLLCALPILVKWVLIGRWKPQQFRVWSLPYLRFWVVKTLIRANPLVLFVGSPLYT
                     LYLRALGAKIGRGVTVFSRNVPVCTDLLALGDGTVIRKDAFLNCYRAQAGLMQTGTVVL
                     GKNVVISEATVLDIETALGDGAQLGHASSLHSGQVVPDGEHWHGSPAQRTDVDYRVVGP
                     ARCGALRRTVHSALQLVTVLLLYVPLAVGGVGILLAEAPQLTAVLEPGPTALGDGTFYM
                     DALLLSLLFFAAVPLGLLFQATVPRLLSRTITPGRVYPLYGFHYAVHRLIALTTNRKFL
                     MRLFGDSSAIVHYLRGLGYDLSRIEQTGSNFGTEVKHETPYLSSVGSGTMVADGLSVMN
                     ADFSDTSFRVCRTSIGPRNFLGNRIAYPSRGKTGDNCLLATKVMVPVDGEVREGVGLLG
                     SPSFEIPRSVQRDSTFDQLKSGEQLRRHLTAKNRHNAATMALYLLVRWLYFFWVTLLVA
                     VAAELYDSLGALAIALGNVLVLVSGVVYFVLVERAVTAFHPLSPLFCSIYDPRFWRRER
                     FWKVPSETYLLFFNGTPFKNLIWRLLGVRIGRRVFDDGCYLTERTLAAIGDGCTLNVGS
                     VVQCHSQEDGTFKSDRSTLGAGCTLGVGAFVHYGVAMGDGAVLAPDSFLMKGEAVPPHT
                     HWGGNPA"
     aSModule        complement(18616..21003)
                     /domains="nrpspksdomains_TU31_RS10540_PP-binding.1"
                     /domains="nrpspksdomains_TU31_RS10540_TIGR02353.1"
                     /incomplete
                     /locus_tags="TU31_RS10540"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(20818..21003)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TU31_RS10540_PP-binding.1"
                     /evalue="1.00E-10"
                     /label="TU31_RS10540_PP-binding.1"
                     /locus_tag="TU31_RS10540"
                     /protein_end="98"
                     /protein_start="36"
                     /score="33.7"
                     /tool="antismash"
                     /translation="TLAEVMGTGQTPVDRNFFDDLGADSLVMAHFCARVRKRADLPPVS
                     MKDIYRYPTIRALATAL"
     gene            21561..22154
                     /gene="sigK"
                     /locus_tag="TU31_RS10545"
                     /old_locus_tag="TPA0598_03_02740"
     CDS             21561..22154
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene="sigK"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009714053.1"
                     /locus_tag="TU31_RS10545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02740"
                     /product="ECF RNA polymerase sigma factor SigK"
                     /protein_id="WP_078885748.1"
                     /transl_table=11
                     /translation="MSHTAPEGPRPPERSAADRHVDDLLVRVAQGDERAFVGVYDALVV
                     PVMGLAARILRDEAQAEEVAQDVMIEVWRKADRFRPERGAAKSWVLTLAHRRAVERVRS
                     VRAGAERERKAAQLAHQTPFDEVVEAVEEREERAQVYRCLAGLGNTQRLPLVLAYYQGM
                     TYAEVAEALSTPAGTVKTRMRTGLRRLRVCMGGD"
     gene            22154..22444
                     /locus_tag="TU31_RS10550"
                     /old_locus_tag="TPA0598_03_02750"
     CDS             22154..22444
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024881.4"
                     /locus_tag="TU31_RS10550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02750"
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="WP_042153719.1"
                     /transl_table=11
                     /translation="MSAAEDPHEALGAYVLHALPPEEAAAFATHLAGCDACTREVADLE
                     ATVACLAEAEAVTPSDALRRRVLERIATTAQEQLLRREPSRREGPRLDLEV"
     gene            22583..23362
                     /locus_tag="TU31_RS10555"
                     /old_locus_tag="TPA0598_03_02760"
     CDS             22583..23362
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049719.1"
                     /locus_tag="TU31_RS10555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02760"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_042152609.1"
                     /transl_table=11
                     /translation="MTAEWRPVRQSRTHELVLERIEERVLAGELKAGDRLPPERELAPV
                     LGVSRSALREALRVLETIGVLVAQAGRGPDAGARIVRNPDDALGRLLRLHFALGSYRLH
                     DVLEARVVLERSSFEAAAEHASAQDLDEAEALLERMREPGVGAADFNDLDTRFHVAIAR
                     SSGNQLTSTLTSAVRESVRPLILRALETAEDWPATAAALNAEHTELLRLVRAGKGAKAA
                     DLAEAHIRGFHGRLVDENAPAEQEQEQGDEGRAGTDR"
     gene            complement(23387..25060)
                     /locus_tag="TU31_RS10560"
                     /old_locus_tag="TPA0598_03_02770"
     CDS             complement(23387..25060)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010641387.1"
                     /locus_tag="TU31_RS10560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02770"
                     /product="L-lactate permease"
                     /protein_id="WP_042152612.1"
                     /transl_table=11
                     /translation="MATTPPAALAAYTPDVAAVGDSLTTTALLGLVPLAAFFLLLMAAK
                     RSALHSALGALLTALLVAVLGFGMPLRLGALSATQGAAFGLFPVMLIVVSAIWFYELTV
                     VSHRFDDLRRSFNAVGRGDLRIQAMLIAFCFGGLLEALAGFGAPVAITAAMLMALGLPR
                     LTSAVTVLVANTAPVAFGAMAIPITTAGNLTGIPAESLAAVIGRQSPLLALFVPQLLLF
                     LVDGRRGLRQLWPVALVTGAVFALAQFWCSAHFAYELTDVVAALAGFGAAVVMLRFWTP
                     TTPDDQRSQVTAEPLTRRRTFLAVLPYLLVIAVFALAKLDVGGLDIPGLLGSLTLQLDW
                     PGLYGHLLAPDGSPAGSAVYKLEVLANPGTLLLLSGLLVMLIYSRAKDADRFPMTARTG
                     LSCAVRTLRNMRTAIATVATVMALSYVMNQSGQTLAIGTWLAAAGGLFALLSPVLGWLG
                     TAVTGSDTSSNALFATLQQTAGKTAGIDPTLLVAANTTGGVVGKLISPQNLTIAATAVE
                     RPGTERILLRKVAGYSVAMLAVLCVLVYLQSLPVLSWMLP"
     gene            25267..26034
                     /locus_tag="TU31_RS10565"
                     /old_locus_tag="TPA0598_03_02780"
     CDS             25267..26034
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049720.1"
                     /locus_tag="TU31_RS10565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02780"
                     /product="(Fe-S)-binding protein"
                     /protein_id="WP_042152615.1"
                     /transl_table=11
                     /translation="MRIALFATCLGDTLFPEAVKSTAVLLARLGHDVVFPPQQTCCGQM
                     HVNTGYQREPVPLVRNFAEQFGDPAIEAVVVPSGSCAGSVRHQHELVAERYGDAALRAG
                     VAAVRTKTYELSEFLVDVLDVTDVGAYFPHRVTYHPTCHSLRMLRVGEKPLRLLRAVEG
                     IDLVELPEADACCGFGGTFAVKNAETSTAMLRDKMDHITGTGAAVCTAGDSSCLMHIGG
                     GLSRIRSGTRTLHLAQILAATRTAPHVLTEAAR"
     gene            26031..27602
                     /locus_tag="TU31_RS10570"
                     /old_locus_tag="TPA0598_03_02790"
     CDS             26031..27602
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129011.1"
                     /locus_tag="TU31_RS10570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02790"
                     /product="LutB/LldF family L-lactate oxidation iron-sulfur
                     protein"
                     /protein_id="WP_042152617.1"
                     /transl_table=11
                     /translation="MSSPTGPATRGTFLGMPAVPPRSPYGTGHLRGEHSFPRAAHDELG
                     NEQLRRNLGKATHSIRAKRLAVTGELPDWEQLRDAGSAIKTDTMNRLPELLEQLERKVT
                     ERGGTVHWARDGVEANEIVTRLVRETGSDEILKVKSMATQEIGLNEHLASQGIAALETD
                     LAELIVQLADDRPSHILVPAIHRNREEIREIFLRHIPGVDPALDADPARLAAAARAFLR
                     EKFMTAKVAVSGANFGIAETGTLAVVESEGNGRMCLTLPETLITVMGIEKVLPRFQDLE
                     VFLQLLPRSSTGERMNPYTSLWTGVTPGDGPQEFHLVLLDNGRTAALADRIGRAALHCI
                     RCSACLNVCPVYERTGGHAYGSTYPGPIGAVLTPQLAGMHGAKNDPNSSLPYASSLCGA
                     CFDACPVKIDIPSLLVELRHQHTEQSGTTAEKLAMKAAAAVMKRPGLFTAAQKAAGLGR
                     GAAGRDGTLSHLPPPLNGWSDSRDTPAPPKQTFRSWFASAEGAAAMRAAAEEGARHTDD
                     DPQEAS"
     gene            27599..28237
                     /locus_tag="TU31_RS10575"
                     /old_locus_tag="TPA0598_03_02800"
     CDS             27599..28237
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964685.1"
                     /locus_tag="TU31_RS10575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02800"
                     /product="LUD domain-containing protein"
                     /protein_id="WP_107070663.1"
                     /transl_table=11
                     /translation="MTATARETVLHRVRDALALSDGPEVTVPRGYRTGRSLPDEERLAL
                     FVDRLVDYRAQVRTCTAATTAAVLAEVLQAHGARKIGVPPGLDPAWLTGYDGETVTDSA
                     DVPAPSLDGLDGVVTGSAVSCAETGTIFLDGAAADQGRRALTLVPDLHVCVVELSSVRT
                     GVPEAVAQLTPEHPITLISGPSATSDIELERVEGVHGPRTLAVVIRTDR"
     gene            complement(28390..29184)
                     /locus_tag="TU31_RS10580"
                     /old_locus_tag="TPA0598_03_02810"
     CDS             complement(28390..29184)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541032.1"
                     /locus_tag="TU31_RS10580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02810"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_042152623.1"
                     /transl_table=11
                     /translation="MRIALCQMTASTDPKENLAIVQDQVRRAAREEARLAVLPEAAMVR
                     FGAALGQVAEPLDGPWAEGVRAVARETGVTVVAGMFTPADDGRVTNTLLATGPGVEEFY
                     DKIHLYDAFGFRESDAVAPGKRVVTIDVDGVRVGLATCYDLRFPELFRAHADAGATVSV
                     LPAAWAAGPGKRAQWDLLVRARALDATVWLAAVNQAAPDPQADPEAPTKAPTGVGHSAL
                     IGPDGTVRGQLGDRPDLLVGDVDTEETARVRRAVAVLDNRSL"
     gene            complement(29505..30926)
                     /gene="aspA"
                     /locus_tag="TU31_RS10585"
                     /old_locus_tag="TPA0598_03_02820"
     CDS             complement(29505..30926)
                     /EC_number="4.3.1.1"
                     /GO_function="GO:0008797 - aspartate ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aspA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123945.1"
                     /locus_tag="TU31_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02820"
                     /product="aspartate ammonia-lyase"
                     /protein_id="WP_042152625.1"
                     /transl_table=11
                     /translation="MTSAGHRREHDLLGDREIPAEAYWGVHTLRAVENFPITGTPIATY
                     PHLINALAAVKEAAARANQDLGLLDTERADAIAAACREIRSGGQLHDQFVVDVIQGGAG
                     TSTNMNANEVIANRALEILGHEKGDYRHLHPNEHVNLSQSTNDVYPTAVNVATIIAVRE
                     LLDSMTVLRTAFAAKAEEFRDILKMGRTQLQDAVPMTLGQEFSAYAVMLEEDQSRLAEA
                     VLLIHEINLGATAIGTGLNAPKGYAEAARTHLAALTGLPLVTAANLVEATQDCGAFVHL
                     SGVLKRIAVKLSKSCNDLRLLSSGPRAGLAEINLPPVQAGSSIMPGKVNPVIPEVVNQV
                     AFEVIGNDVTITMAAEAGQLQLNAFEPVILHSLSESITHLGAACRTLAERCVAGITANT
                     ETLRASVQNSIGLVTALNPHIGYTAATAIAKEALATGRGVAELVLEQGLLPADRLAALL
                     RPEEIAGTGGDLSAV"
     gene            complement(31015..32034)
                     /locus_tag="TU31_RS10590"
                     /old_locus_tag="TPA0598_03_02830"
     CDS             complement(31015..32034)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308035.1"
                     /locus_tag="TU31_RS10590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02830"
                     /product="asparaginase"
                     /protein_id="WP_042152628.1"
                     /transl_table=11
                     /translation="MSQSTTLPPHRTAGAPPAVREPAHVPVAHVVRGGIVEGVHHGSVV
                     VLAADGSVAFQAGDIEAAFYPRSALKPVQAVGLLRAGLPPLDDPSLALVAASHSGEDRH
                     LATARDILAAGELTEDELRNVPDLPYDPAVRDEWIRRGLGPTRLAQNCSGKHAAMLLTC
                     RARGWDLDSYLDPGHPLQRELAATVEDLTGQGIARVTVDGCGAPLFSVSLHGLTRAAAR
                     LATAAPGSEEGRVAHAMRTHPEMVSGSRRDVARLVRAVPGLLAKDGFEGVQIAALPDGR
                     AVGVKIADGGDRARMPVTAAALARCGIDPGVLAPFATTPVIGGGTPVGALRAADTLAP"
     gene            complement(32037..33611)
                     /locus_tag="TU31_RS10595"
                     /old_locus_tag="TPA0598_03_02840"
     CDS             complement(32037..33611)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982755.1"
                     /locus_tag="TU31_RS10595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02840"
                     /product="amino acid permease"
                     /protein_id="WP_370682718.1"
                     /transl_table=11
                     /translation="MSEQSLRQAERQQQQSASQDAHQQAGGHVDAGDAGYQKSLTSRHI
                     NMIAIGGAIGTGLFLGAGGRLASAGPSLAVAYALCGLFAFLVVRALGELVLHRPSSGAF
                     VSYAREFLGEKGAFVAGWMYFLNWATTGIADITAVATYTHYWGMFSEIPQWVIALIALA
                     VVLTVNLISVKIFGELEFWFAIVKVGALVVFMLIGIFLLVTQHPVAGHSPGPSLVTDHG
                     GVFPTGTLAMLLVIQGVVFAYASVELVGVTAGETAEPEKVMPKAINSIMWRVAVFYVGS
                     VVLLAMLLPWSAYSAGESPFVTVLSKIGIPAAGGVMNLVVLTAAMSSLNSGLYSTGRIL
                     RSMAMSGSAPRFTGVMSRSQVPYGGILLTSGVCVLGVGLNYVVPSEAFEIVLNFAAIGI
                     LSTWSMIMLCHLLFWRKARAGQLIRPSYRLPGSPWTECVTLAFLALVLVLMWADGGAGR
                     TTVLSLPLIVAALVGGWFLVRRRVGILQDAAAAQASGAHPHTAPPAQHTENTHGTDNPH
                     GTESTEN"
     gene            complement(33608..34345)
                     /locus_tag="TU31_RS10600"
                     /old_locus_tag="TPA0598_03_02850"
     CDS             complement(33608..34345)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007380009.1"
                     /locus_tag="TU31_RS10600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02850"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_078885685.1"
                     /transl_table=11
                     /translation="MNLSDSQTAGEMPRRISAMEAVLNHLRGAIERGEYAVGDKLPSEA
                     ELCRRLEVSRPVLREALRALQTMGLTVSRTGKGTFVISDGAVADPTFGDYAASDLLEVR
                     RHVEIPVAGYAAVRHTAEDLDQLNHLLDRMEQETDTTAWVAMDSLFHLAIAQAAGNPVF
                     RRVIEEIRDALARQSAFLNELGGRREQSNREHRAIVEALVDRSEHDAVEAMAHHLARVE
                     TTLTTIVRSQHRTDPSTEDEDHA"
     gene            complement(34475..35080)
                     /locus_tag="TU31_RS10605"
                     /old_locus_tag="TPA0598_03_02860"
     CDS             complement(34475..35080)
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014176303.1"
                     /locus_tag="TU31_RS10605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02860"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_245698487.1"
                     /transl_table=11
                     /translation="MNPTTHNGMDPEPEILDALQLAADADRATDFAEAAHRILADLVSG
                     GAPLGWVDPPGRGEVAELVDRVVRAAHTGDGALRAAYAGPRLVGLGYWLRYARPTNRQH
                     ADLEKIAVASEAHGQGLGRSLTSALVEDARGAGIEVLTLDARADNTRALTLYRSLGFRE
                     YGRLPDFVAMGGRRYDKVFYMLDFRGDGRHDGEWPHPQ"
     gene            complement(35271..35963)
                     /locus_tag="TU31_RS10610"
                     /old_locus_tag="TPA0598_03_02870"
     CDS             complement(35271..35963)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606645.1"
                     /locus_tag="TU31_RS10610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_03_02870"
                     /product="response regulator"
                     /protein_id="WP_042152634.1"
                     /transl_table=11
                     /translation="MIDVLVVDDDFHVAEINAAYVSQVSGFRVTGRAHTAAQALATLER
                     THVDLVLLDHYLPDETGLSLVRRLRQLGHRTDVIMVTAARDVGTVQDAMRSGALQYLVK
                     PFGFSGLRTKLDGYAALRRTVEGIGGRGEAGQEQVDRIFGAFRTTDSPHTELPKGHSAA
                     TVDLIRRVLGASGHPLSAHEVAERAGVSRSTAQRYLKHLERSGHIILTLKYGDTGRPEH
                     RYRWAGTH"
ORIGIN
        1 agtgatctat agccgggaag cggtccaatc cggacgaagg aacgttgtcg cagtcatgga
       61 accgagggag ttgtgggagc gccacgcggt actcgcacag gcgttttgca gcagcgatga
      121 cgaggtccgc cgtacacagg gactcctcga cgaggccgag gcccgtcgtt cgcggaccct
      181 ggccgccttc gccgtgaccg tgggcagcga cgcggtggtg gcggatctgc tcggcctgga
      241 ggaacgcgaa gtgcggctgg cccggcgcac ggtgggcaag gaagacgccc gcgcggtcgc
      301 caagagcctg ctcgcccagc ccccgtgcga gcccgccccc gcaccgcagc agcccgcgcc
      361 ccaggccccc gcggcgcaag cccccgcacc gcagccccct cagggcgccg ccgcgccggg
      421 ccccgtcgcg ccgccgcccc aacaaggccc ggccgccgcc ccccagccct ccgaaccggc
      481 ctgggccccg gcgctggacg cggtcctgat gagcagctgg cacaacggcg tcgacctcac
      541 cgccctggcc accgaactcg gcctcgacgt ccggctgctg gtggcccgcg cacaacaact
      601 gtccgcagag agccgcccga tgccgcccac cccctcggac cgcacgggac ggcaccgccg
      661 gctggtcaat gtcccgcccc cacagccgga gacgccccat ctgacatggc gcgagcgacc
      721 acagcagccc ccacgggagc actacgagca ggagcactgg aagcaacagc cgtaccagca
      781 ctacccggac cagcagcagt accaggaata ccgggtgtac gaggaacacc agcagtatca
      841 gcagcccacc cagcccactt gggatgccaa tgccatcacc gccgcccagc acgactggga
      901 cggcatcctc agtcaatggg aggccaccgc cgcaccccag ccaccccttt ccgcgcccgg
      961 tcagggcggc gggtaacggg gccgcgccgc cgggcgccgg aggcatccgg gccggcgggc
     1021 gcgtcggccg ccgggcagtg gccggtgccg ccgctgggcg gaaaaccgga cgccgttcca
     1081 tcctgacgtc gattacagtg ggcgccgagc cgtgactggc gcttgggtgg agtaccaccg
     1141 gggagcggct cggccatcca cggtccgtgc cgcgcgcctg ggcgatccca cacgacgctc
     1201 aggagcagcc catgtccccg gacgcccgcc tcatggacgg cagcgcactg gcccgcagca
     1261 tggtcgaaaa ggccgcccgg cgcgcggccg acctcaccga acggaccggc acggcaccgt
     1321 gtctggcgac cgtactcgtc ggcgacgacc ccgcctcggt gacgtatgtc cgtatgaagc
     1381 gcaaccgctg cgcgaaggcc gggatacttt cccggcatgt ggcgctgccc gccgccacca
     1441 cgaccgcgga gctggtcgac acgatcaccg cactgtcgaa cgaccccgcg gtgcacggca
     1501 tcctgttgca gcacccggcc ggcccgcaca tcgacgagcg cgccgcgttc gaggcgatcg
     1561 cccccgagaa ggatgtcgac ggcgtcacct gccactcctt cgccgcgatg agtttcggcc
     1621 tggacggctt cgcctcctgc acgcccggcg gcatcctgcg gctgctggat cactatgacg
     1681 tcgacctggc cggtaagcac gcggtagtgg tcggccgcag cgcgatcctg ggcaagcccg
     1741 tggggatgct gctgctcggc cgcaatgcca ccgtcaccta ctgccactcc cgcaccaccg
     1801 atctggcgtc gctcaccagg gaggccgatg tgctgatcgc ggccgtcggc cggccccggt
     1861 tcctgggcgg tgagcacatc aagcccggag ccgtcgtgat ggacgccggc tccaacccgg
     1921 gcaacgtcgg tgatgtggac ttcgacgcgg cacgcacccg cgccgccctg atcaccccgg
     1981 tccccggcgg cgtcggcccc atgaccatcg ccaccctgct cacccagacc gtcgacgccg
     2041 cgtccgccca gctgaacgcg gtctgaccgc cgcccgacgc ggggccggga agccgcccgg
     2101 cggagcgggc ggtggcgccg ggcgcggcgg cgcggctgcg cccggcgcgt ccggtgtcag
     2161 ttcagcgtcc gcagcatcga ggcgtcgaac ggcaccaggg cgtcggtgcg gccctccagg
     2221 atcttggcgg cccactccgg gtcgccgagc agggcccgtc cgatggcgac gaggtcgaac
     2281 tcgtcccgct ccagccggtc cagcagccgg tcgataccgg agacccccgc ctgttcgccc
     2341 tggaacgtcc cgatgaactc gttgtcgaga ccgaccgagc ccacggtgag ggtgggccgg
     2401 ccggagagct tcttgaccca tcccgcgaga ttgaggtccg agccctcgta ttcgggcagc
     2461 cagtagcggc gcgtcgagca gtggaacgcg gtgacgccgg cgtccgtcag cggtgccacg
     2521 atctcctgga gttcctccgg cgtctcggcg agccgggcct cgtagttgcc catcttccac
     2581 tgggacatcc ggaagaggac cgggaagccg ggcgagaccg ctgcccggca ggccgccacg
     2641 atctcggcgg cgaaacgggt acgggcggtg cggctgccgc cgtaggcatc ggtccgccgg
     2701 ttcgtgcccg accacaggaa ctggtcgatc aagtagccgt gcgcaccgtg cagttcgact
     2761 ccgtcgaagc cgagccgctc ggccgtggcc gccgcctcgg cgaacgccgc gatgacctcg
     2821 tcgagatccc gctgtgtcat ggcgtgcccg gacggggtgc cgtcgagggc gatgccggac
     2881 gggccggacg gcggggcgtc ggggaacggc ggtgcgcccg ccttacgggc catgccgacg
     2941 tgccacagct gcggcatgat cgttccgccc gccgcgtgca ccgattccac gacccggctc
     3001 cagccgtcga gtgcgtccgc gccgtggaag cgggggacgg cgccgctggt gccggcggcg
     3061 gggtgcccga cgtaggtccc ctccgtgatg atcaggccga cgccgccggc ggcgcggcgt
     3121 gcgtaatagt ccgcgacatc ggcgcccggg acaccgccgg gcgagaactc gcgggtcatc
     3181 ggcgccatgg cgatccggtt gggcacggtg cggccgccca gggcgaaggg gcgggagagc
     3241 gtctgggccg cacgggtggc ggcggcgctg gcagtcacgt gtgggtctcc tgggaagaca
     3301 acgcgggcgc ggaacgacgc cggccggcag acgttccgct gttccgaaca ccacacggcg
     3361 ctgccgtcat ccgccgcgca ctgtctgctg cgccacagtc gccaccccgc ggtcgtcgca
     3421 ccgccgccac gcaccgccgc gggcaccccg ccgtcgcccc cgcggccgtt ccgctgccgc
     3481 gtcgcaccgc cggccgcggt caggtggtga ccggctgggc ggcgcgggcg agttcacggc
     3541 ggaggcgcat gaaggggcgg gggcggttga gggccaggac ggcggtggtc cgcccgtcgc
     3601 gttcgtagca ggcgaggaag ctgcggtcgt cgggcgagcc ctcgacgatg cgcggggtgt
     3661 cggtgggcag gcgccggccg gcgaactgga tgcgtacgcc gtactggtcg gaccagaagt
     3721 acggcaggct ccgatgggcc gcgacggtgc ggccggccag caggttccgg acggcgacgg
     3781 cggcctgttc ggtggcgctg gtccagtgtt cggcgcgggt gccgtccgcc ctggcgacat
     3841 cgccgaccgc cacgatgtgg ggctgagggg tggccccgcc ggcgtcgcag cacaccccgt
     3901 cgtcgagcgg gagtccggag ccttcgagcc aggcggtgtg ggggcgtacc ccgatgccga
     3961 tgacgaccac ctcggcgggg agcagccggc cgtcggtcag ctcgaccgcg gagacacggt
     4021 tcccggtgcc gccgtcgtgc aggcgggcga caccggttcc ggtcagcagg gtgacgccgt
     4081 ggtccgcatg gagggtggag cagatcccgg ccatcgcctc gccgagttgg gggacgaggg
     4141 ggagcggggc ggcttcgacc acggtgacgt catggccgag tgcggcacag gacgaggcga
     4201 cctcggcgcc gatgaagccg ccgccgatca ccacgaccct gaccggcccc cgggtcagct
     4261 ccgcgcgcag ggcctgggcg tcctcaagag tgcgcagggt gtgggttccg gcgggggccg
     4321 ggccggggag gcggcgcggg gtggcgccgg tggcgatcac cacaccgtcg gtggtcaggg
     4381 accggcctcc gtcgaggagt accgcgcgcc catgggtgtc gagcccggtg gcgcgggtgc
     4441 cgagtcgcca ttcggcgtcc agttcggcgg tctcctcggc gtcggcgagg gccagttgac
     4501 ccaggtcagc ggtggcgccg gtgaggaagc ccttggacag cggcgggcgg tcgtaggggc
     4561 ggtggtgttc ctccccgacg atcaccaacc ggccgtcgaa tccctgggcg cgcagggccc
     4621 gcgcggcgta gaggcccgcc agcgaggccc cgatgacagc gaccgacttc atgcggcggt
     4681 gccttcctcg gcggcgtggt ggtggacgta gatcatgccg tcctcgacgg tcacggggtg
     4741 ggtgcgcacg gcccggcggg cgggcaggca ggtcgccgct ccggtgcgca gatcgaacga
     4801 cgcggcgtgc agcgggcatt cgaccaggca tccctccagc cagccgtccg agagggaggc
     4861 gtcctggtgg gtgcaggtgt catcgatggc gtacagctgc ccgtcggcat ggaagacggc
     4921 gatcggaggt gcggtgtcga tgcgtacgga ctcgccggtg ggcaggtcgg cgagcgggca
     4981 gacaggaatc acaggacccc cctgttactg ttcggtatca tcgagtttcg cgttgcgcac
     5041 gatgaggcgc catgcgcaac agaatccagc cggggagcgc ctgcgtcaag cggtccccgg
     5101 aaatgccgaa ccttcgaatc ccgggcctcg gccggggtgc caggtggtga gatccaacag
     5161 atgacggaca gcgtggaggg gcgggcggag gccaagccgc cgaaacagcc gggcggtgtg
     5221 cagtcggtgg accgggccgt gaccgtgctg gaaatcctgg cgcggcacgg cgaggccgcc
     5281 gtgaccgaga tcgccgagga gttgggcgtc cacaagtcga ccgcgttccg gctgctcggg
     5341 gtgctggaga accgcgggct ggtcgggcag gagcaggaac gcggcaagta ctacctcgca
     5401 gccggggtgc tgcggctggc cggagcggcg gccgtacggc tggacatctc ccaggaaggc
     5461 gcgccggtct gccggcagct ggccgaggag ctgggggaga cggtcaatat cgcggtgctg
     5521 gagagcgacg ccgcggtcaa cgtcacgcag gcacgcggcc cggcctcggt caccgcgcag
     5581 aactggctcg gccggcgtac gccgctgcat gccacctcca gcggcaaggc gctgctcgcg
     5641 taccagccca gggcggtcca ggaggccgtg ctggcacgga agttgccgcg gctcaccgag
     5701 cggacggtca cctcggcggc cgcgctgcgc cgtgagctcg ccgaagtggt cgagcggggt
     5761 ttcgcggtgg cgatcgagga gctggagctc gggctgcggg cggtcgcggc gccggtgcgg
     5821 gggcccgacg gctcggtgat cggggcgatc agtgtgtcgg tgcccgccta ccggctggcc
     5881 gaggagcggc tgcccgaggt cgtcaaggcc accgtctccg cggccgagga gctgtcgcgg
     5941 cggatggggt acggccgttg acccggtgac gggtcagggc ggcggaggcg gggccggggc
     6001 gtacgttccg gccccgccgc cgtgtccggg cgcgcgggca atccgttgcc aagagctggc
     6061 tcgtacctct tgacggtgcc gatccggcgt tcccactatg tctctcatcg cgcaaccagt
     6121 cgtgcagtgc gcaacactga ggggtagggc atgccacacc acgtccatgc cgtcgtcgcg
     6181 gcgaaacaag gcgcaccggt cgagccgcag acgattctgg taccggaccc cggcccggga
     6241 gaagtgctcg tcaccgtgca ggcctgcggg gtctgccaca ccgacctgca ctaccgggaa
     6301 ggggcgatca acgaccaatt cccgttcctc ctcggccatg aggcggccgg tgtcatcgag
     6361 tccgtcggcc ccggcgtcac cgatctcgcc cccggcgact atgtcgtgct cgcctggcgg
     6421 gcgccctgcg gcagctgccg gtcctgtcgt cgcggccggc cctggtactg cttcgactcc
     6481 cgcaacgcca cccagccgat gaccctgctg gacggcactc cgctcacccc cgcgctcggc
     6541 atcggcgcct tcgccgagaa gacgctggtc gccgccgggc aggcggtcaa ggtcgacccg
     6601 cacgcccgtc ccgaagcggc cggtctcatc ggctgcggag tgatggccgg ttacggggcg
     6661 gcggtgcaca ccggcggggt cggcagcggg gacaccgtcg cggtcatcgg ctgcggcggg
     6721 gtcggcaacg cggcgatcgc cggggcctcg atcgccgggg cgcgccggat catcgcgatc
     6781 gacatcgacg accacaagct ggacggcgcc acccgcttcg gagccaccca caccgtcaac
     6841 tcccgtggca cggaccccat cgaggcggtc cgcggactga ccggcggcca tggcgcggat
     6901 gtggtgatcg acgcggtggg ccggccggag acctacaccc agggcttcta catgcgggac
     6961 ctggccggca cgctggtcca ggtcggcgtc cccgaccccg gcatgcgcct cgaactgcca
     7021 ctcatcgacc tcttctcgcg cggcggcgcc ctgaaatcct cctggtacgg cgactgtctg
     7081 cccagccgcg atttccccgt gctcatcgac cgctacctca gcggacggct cgacctcgac
     7141 ggatttgtca ccgagacgat cggcctggac gaggtggagt ccgcgttcga caagatgcgc
     7201 gacggccggg tactgcgctc cgtcgtggtc ctgtaacggc gtcacactca ccccagtgga
     7261 ccaccccgac cagcaggagg agggacatgt cccgtacgcc cgcccccagt tcccgtgtgg
     7321 ttgtcatcgg tgccggcatc gtcggctgct ccctcgccga tgagctgacc gcccgcggct
     7381 ggaccgatgt caccgtcctc gaacagggcc cgctgccggc ccccggcggc tccacctcgc
     7441 acgctcccgg cctggtcttc cagaccggcc cgtccaagac cctgaccgag ttcgccgcct
     7501 acaccgtcca gaagttccgc tccctcgatg tggacgggct gtcctgcttc aacccggtcg
     7561 gcggtctgga gatcgccacc accgaggccc gctgggccga tctgcaccgc aaggccggac
     7621 tcgcggcctc gtggggcgtc cgtggtgaac tgatcggccc acagcagtgc aaacgcctgt
     7681 ggccgatgct gggcgagacc acgctccacg gcggattcca cacccccgac gacggcctgg
     7741 cccgcgccgt gctcgcctgc cgcgcccaga tcgcacgggc cgagagccgc ggcgcccgct
     7801 tcctggagcg gcacaccgtc accgggatcg agcgggcgga cggccgggtc accggcgtca
     7861 ccaccgaccg cggcaccttc cccgccgacc atgtcgtctc ggccgccggc ttctggggcc
     7921 cggtgatcgg cgcgatggcc ggggtggacg taccgctcct cccgctggcc caccagtacg
     7981 ccaccaccgc accgctgccc gagctcgccg gcgtcaacga cccgcggact gaggcgagca
     8041 agccgatcct gcgcttccag gaccgcgacc tctacttccg cgaacacacc gaccggatcg
     8101 gcatcggctc ctacgcccac cgcccgatgc ccgtcgaccc cttcaccgtc gccgccttcg
     8161 acgacgctcc cgtgatgccg tcctcgctgc ccttcaccgc ggaggacttc gcgccgagct
     8221 ggcaggacag catcggactg ctgcccgcac tgggctcgtc ccgggtggcc gagggcttca
     8281 acggtgtctt ctccttcacc cccgacggta tgccggtcct cggcgaatcc cgcgaactgc
     8341 gcggattctg gctggccgag gcggtctggg tcacccactc cgcgggcgtc gccaaggccg
     8401 tcgccgagtg gatgacggac ggccggcccg ccaccgacat ccatgagtgc gacctctacc
     8461 gcttcgagga cgcccagcgc tcgcccgcct acatcgccga ccgcggcgcc cagaacttca
     8521 tcgaggtcta tgacgtcatc catccgcttc agcccatgga agcgccgcgg ccgctgcgca
     8581 ccagcccctt ctacccacgg cagcaggagc tcggcgcgta cttcctggag ggcggcggct
     8641 gggagcgccc gcactggtac gaggccaacg ccccgctcgc cgaagggctc cggcttcccg
     8701 agcgcgacgc ctggtcggcg cgctactggt caccgatcgc cgccgccgaa gcccgcgcca
     8761 cccgggaaaa ggtcgccctc tacgacatga ccccgctgcg caggctggag gtcaccggcc
     8821 ccggcgccct cgccttcctc cagcggatga ccagcaacaa cctcgcgaag aagcccggcg
     8881 cggtcaccta caccctgctg ctggacgaga ccggcggcat ccgctccgac ctcaccgtcg
     8941 cccggctcgc cccggaccgc ttccaggtcg gcgccaacag cggagccgac ctcgactggc
     9001 tgctgcggca cgcccccgac gagggagtcc aggtccgtga catcacctcc ggcacctgtt
     9061 gcatcggcgt ctggggcccg ctcgcccgcg ccctggtcca gcccctgacc cgcgacgact
     9121 tctcgcacca ggccttcggc tacttccggg ccaggcagac ctacctcggc catgtcccgg
     9181 tcaccgccat gcgcctcagc tacgtcggcg agctcggctg ggagctgtac accaccgccg
     9241 atatgggcct gcgcctgtgg gacacgctct gggaggcggg gcaggagcac ggggtgatcg
     9301 ccgccgggcg cagtgccttc aacagcctcc gcctggagaa ggggtaccgc gcctggggcc
     9361 atgacatgac caccgagcac gacccctacg aggccggggt cggcttcgcg gtccgccccg
     9421 ccaagggcga cttcatcggg cgggcggcgc tggagggcat gaccgaggag accgtctccc
     9481 gcaggctcac ctgcctcacc ctcgacgacc ccgcggccgt cgtcctcggc aaggaaccgg
     9541 tccatgtgga cggcgctccg gccggttatg tcacctccgc cgcctacggt tacaccctcg
     9601 gccgcgggat cgcctacgcc tggctgccgg ccggcgcggc ggcccccggc acccccgtac
     9661 acatcgagta cttcggcgag aagatccccg ccaccgtcgc ccaagagccc ctcttcgacc
     9721 cgcagatgga gcgtatccgc aggtagcccc gggacccgtc cacggtgctg gtgatccgct
     9781 cgtcctccgt acgcagaagg agcaaccgca tggctcccac ctacgacgtc atcgttctcg
     9841 gcctcggcgg catgggcagc gccgccgccc accacctcgc cgcccggggc gcccgggtcc
     9901 tgggcctgga gaagttcggc ccggtgcaca accgcggctc cagccacggt ggttcccgca
     9961 tcacccgtca gtcctacttc gaggaccccg cctacgtgcc gctgctgctg cgctcgtacg
    10021 agctgtacga gaagctggag cgggacagcg gccgggagat cgccaccctc tgcggcgggg
    10081 tgatgctcgg ccgccccgac agccgtaccg tccgcggcag cctggaatcc gcccgccagt
    10141 gggacctccc gcacgagatg ctcgaaccca aggagatccg ccgccgcttc ccgaccctga
    10201 cccccgccga ggacgaggtc gcgctgtacg aggcacgggc gggcctggtc cggccggagt
    10261 acaccgtcgc cgcacatgtc cagctcgccg gccaggacgg cgccgagctg cacttcgagg
    10321 agccggtcac ccgctgggag gagctgccgg gcgccgccgg ggtccgcgtc cacacccccg
    10381 aaaacaccta caccgcaggc cagttggtga tctgccccgg tgcctgggcg ccccagctgc
    10441 tcaccgacct gggcgtgccg ttcaccatcg agcggcaggt catgtactgg ttcgccccgc
    10501 gcggcggcac cgcgcccttc gtccccgacc ggcacccgat ctacatctgg gaggacgacc
    10561 ggggcgtcca gatctacggc tttccgtcga tcgacggccc cgacggcggc gccaaggtcg
    10621 cgttcttccg caagggcacc gtctgcaccc cggagaccat cgaacgcacc gtgcacgacc
    10681 acgaggtacg cgccatggcc gaccagctcg ccccgcgcct ccccgccctc cccggccgct
    10741 tcctcaaggc cgccacctgc atgtactcca acacccccga cgaacacttc gtgatcaccc
    10801 ggcaccccgg gcacccggag acggtgaccg tcgcctgcgg cttctccggg cacggcttca
    10861 agttcgtacc ggtggtcggc gagatcgtcg ccgacctcgc gctgaccggc accacagcgc
    10921 accccatcga gctgttcgac ccccgccggc ccgccgccgc ggccgcttga ggagagcccc
    10981 catgacgacc acgcccaccg agtcctcgcc ggcacccacc acgcccgcgc ccgctgccgc
    11041 cccgagcctg atcgccaccc tcgccggaca ccactacacc gaccccggga tcttccgcca
    11101 ggagcaggag aagatcttcg agcggctgtg gttctgtgcg gtccgcagcg ccgacctgga
    11161 gaagcccggc gccttccgca ccgtccggat cggccgggag agcgtactga tcacccgcaa
    11221 ccgcgccggt gcgctgcgcg ccttcctcaa catctgccgg caccgcggcg cgcagctgtg
    11281 cacagaggag tccggcgagg tccgccgcaa cctccagtgc ccctaccacg cctggaccta
    11341 cgacctcgac ggccgcctgg tggccgcccc caacctccag aagatgccgg acatcgaccg
    11401 taccgaacgc ggcctggtca ccgtcccgct gcgcgagtgg ctcggctacg cctgggtgtg
    11461 cctggccgac gagccgccgt ccttcgagga caccgtgatc ggcgcggccg tcgagcggct
    11521 gggggacgcc gcctccctcg accgctaccg caccgagggg ctcgccctcg gcaaacgcct
    11581 cacctatgac gtgcgcgcca actggaagct catcatcgag aacttcatgg agtgctacca
    11641 ctgcggcacc atccaccccg aactcaccga ggtactaccg gagttcgccg acggtttcgc
    11701 cgcccagtac tacgtcggcc atggcgcggc cttcgccgag gaggccaccg gattcaccgt
    11761 ggacggcacc gacggcttcg gccggctccc cggcatcgag gacacccagg accgccgcta
    11821 ctacgcgatc accgtccgcc cgcaggtctt cgtcaacctc gtcccggacc atgtcatcgt
    11881 ccaccggatg ttcccgatgg cccccgaccg cacggtggtc gaatgcgact ggctctacct
    11941 gcccgaggtc gtcgactccg gagccgatgt ctccaagtcc gtcgaactct tccaccgggt
    12001 caacgcccag gacttcgacg cctgcgagcg cacccagccg gccatgagct cccgcgccta
    12061 ccgcgacggc ggggtgctgg tgcccagcga gcaccacatc ggcgccttcc accagtgggt
    12121 caccgactgc ctggcgggcg ggagcggctg atccgcggcc tgagttacag tcagcccccg
    12181 ttggcgctcg ggcacatacg agcgcggcac aagggggagc gcaccatgaa cctgtcgttc
    12241 gagcggccgg ccgcgtacga cctgggcgcg gacgcggatc tgggcctgtg gctggccgag
    12301 tgggcggagt acgccgaccg gatcgtccat ctcgggccgg acgacggccg ggaccacggg
    12361 cagctgtgct gggacgtcct ggcgcccacc ggcctgctcg caccgcactg ccgggagtgc
    12421 cggcacccgc acggcggccc gcgccgaccg cagcagatgg cctccgccct gcaccggcac
    12481 atccctccgg ccgaggcatc gccctggatc gcggccaccc tcatccgcag cctcgtcttc
    12541 ccgggcgggg acggcccgat gcggcccgtg gccgacgcgc tcggcgacgg gctggtggag
    12601 ctgctcggcc cggacgccca gtggcgtgcc aatggctacg ccgcgtaccg ggaaggcgcc
    12661 gaaaggaacg tctcctggaa accggtcacc gaggccacct tcgacgcggc cgtggtcggc
    12721 atcggcggtg gccatgccgt ggtcgtggtg gccaccggcg aggactgacc cggcagttcg
    12781 gcctcgtgcg gtgctgcggc gaggggcccg gcctcagccg tcgtcgcgac ggcgccgggg
    12841 ccgcgaggac ggctccagcg gcccgggcgg tggggtgagg ccggacgggg gaagaccgga
    12901 ggcgtcgagc gggggaccgg cggcgaggac gtcctcgccg tacaggtcct gcacccagtt
    12961 gtcgtggtag acggtgtcga gatagcgctc gccgaggtcc ggggcgatgg ccaccgccgt
    13021 acggccccgg gcgtcgtgcc gggtcagcca gtccgtcgcg ccgctgacca cggtgccggt
    13081 cgagccgccg aacacgaagc cgcgtttggc cagccggtgg caggtgcgga tggtgtccgc
    13141 ctccgcgacc cgtaccacgt cgtcgacata ggactcgtcg agcagcggcg gctggacgct
    13201 catgcccagg ccggggatca tccggtgccc cggagtgccg ccgaaggtca ccgagccgac
    13261 actgtccacg gcgacgatcc gtaccggccg gtgccactcc cggaagtagc gggcgcagcc
    13321 catcagggtg ccggtggtgc cggcgccgac gaacagcagg tccagccgcg ggaaagcgcg
    13381 ggcgatggcc ggtgccgtcc tgcggtagtg cgccttccag ttgctcgggt tggtgtactg
    13441 gctgagccac agacagcggt cgtcggaggc gcacagattg cggatgtagg cgagccgggc
    13501 accgaggaag ccgccgttgg actcctggtc ggcgaccaca tgcacctggc tgcccagagc
    13561 ctccatcatc agcctggtgg ccaggttgca gcgggagtcc gtcacgcaca ggaagcggta
    13621 gcccttgctc gccgcgatca tgctcagcgc cacgccgagg ttgccggacg aggactcgac
    13681 caggaccgtc tccggacgca ggtctccggc ccgttcggcg gactccacca tctcggtcgc
    13741 ggccttcagc ttgatcgagc cggcgaagtt gaagccctcg cacttgagga agagggagtg
    13801 cccgaagatc gaccggaggt cgacatagag atcctcctcg ttgaacgcgt agggcgcgga
    13861 tatgactggc acgatggtct cctcacctgc gacagcgcac cgttggacgg tccgtccgac
    13921 cgtggccgct catccgtacc ggcgcagttc gtggaagaag ccgtcgacga cccgcagttc
    13981 cccggaccgg accacctcgt cgtagacgta cttgccgacc gcgagatcga gcaccccgag
    14041 gccgaagggg gagaagacgg cggtccggtc cgcgggcacc gcgacccggc cggccagcac
    14101 gtcgtccagc gtgccgtgca ggaactcccg gttgccggtg agctgttcgg tcagatgcgg
    14161 ggaggtggcg gcgcgcagac agtgctcgat gtcgtcgacg atattggtcg aggtcagcag
    14221 gatctgcggg gcgaggtcgc gcagcgacac atgcaccacc accgggtggt gaccgaacca
    14281 cgagacctcg tggacatggg gccgcggggc gacggtggcg aagaccacca gatcgcttgc
    14341 gcggatcagc tcctccgcac tgtggtgcac ggtgacccgc ccggtggtcc gggactgctc
    14401 caggtacaga cggaagccgg ccgcgctctc cgcggagagg tcgtgcacgc cgatctcgtc
    14461 gaacgaccag ccggtgcctt ccaggaaggt gtggatgtag cgggcgatca ggcccgcgcc
    14521 gaagaacccg acgcgggtcg ggcgggggcg cccgcggctg agccggtcgg ccgccgaggc
    14581 cgccgacgcc gcggtcctgg tcgcgctgat gatcgagctc tccaggcagg cgaacgggta
    14641 gccggtgtca tggtcgttga ggatcagtac ggccgaggcc cgggggattc cggcggccac
    14701 gttcggcggg aagctggaga tccacttcag gccgtccacc cgggtctccc cgccgatcga
    14761 ggcgggcagc gcgatgatcc gggacgacgg gcggtcgggg aggtgcagga aggacgaggg
    14821 cgggttcacc gactcaccgg cgccgtgcag ccggtaggtg gcctcgacca cgtccacgat
    14881 ctccttctcg cggccctcca gcgcctgctg cacctgggca ccggagatca ccgcgaagga
    14941 cggcgtgggg ggcggcccgg gtgtgggccg ggacggggtg ggacggacgg tggtcatggg
    15001 tcagttcacc tcaacggtcg gcgagcagtc ggccaggcgt acggggtcgg ccagggccac
    15061 caccacgtcc cgcggcccct cgaaggcctc ccggctgtgc gcgctgcgga cgttgtcgac
    15121 gagcagcagg tcaccggcct cccacggccg gcgcacggtg tgggcgtcgt agacctcgtt
    15181 gagcaggagg acgacgtcct cggcgagggg ctcgccgttt ccgtagcggg tgttgaacgg
    15241 cagcccgtcg ggcccgtact cgtcgatcag gtactcccgc acttcgggcg ccatcgtcca
    15301 ctcgttgagg aacgcgatct ggttgaacca gcagcggcgg ccgctgacgg ggtggtgcag
    15361 cacggcactg cggcgctggg tggtgcgcag accgccgtcg ggctgccagg cgaagtcgat
    15421 ggcgtgggcg cggcagtagc gctcgacggc gtcccggtcc tcggtgccga acgcctggtc
    15481 cagcgtggcc ccgatctcgg ggtggtagct gcgggtcagc agccagccct cccgctcgaa
    15541 ccgctcggcc agggccgggg gcagcgcgtc cagcacggcc gccgagtcgg ccaccccggt
    15601 ggccccgccg gtggtggggg cgcccaggca cgcgaacagc atcagcccgg ggaactccag
    15661 ggtgtaactc agctcgtgat gcatgcacat cggctggttc gggggccact tcgacgagga
    15721 gtagacgccc tcggagtagg tctgccggag ggcgaaggcc tcccgctcgg tcagcggggc
    15781 gacgcccagg ccgtggcgca cggcgccgac cccggccggg tcgcgcatcc ccaggccccg
    15841 gatcagtacc gcaccgtgct cggcgacgac ggcgcgcagg gcgtcccgtc gctcggccgc
    15901 ccagtgcgcc gcgctgtcgg tggtgccgac ccgcagcatc ggaggtgtgc cgggttcccg
    15961 ttccagttcg ggcagggaga tcgaaagtga cgacaccatg gtggttctcc tctccgtggc
    16021 ggctcgggac gcagccggcc gtgcggtgtc gcaccgcacg gcccgtgcgg cgtcgttcgg
    16081 ttgggtccgt ggcagtccgg cccggtcgtc gatctgccgg gcgagatcgg cgaggaccgg
    16141 atgccgggtg aggtccctga cggagaccgc acggcccagg gagaccgcga gggccacggc
    16201 ggacagcgaa gtgccgccgc agtcgaagaa gttgtcctgc cggccgatcc ggtcccgggg
    16261 catgccgagc acctcggccc aggccgcggc cagccgtcgc tccgtcggcg tacgcggtgc
    16321 gtggtagtcg tcctcgaccg tgtcgagtcc gccggcgagt gcctccagcg ccttcttgtc
    16381 gatcttgccg ttggcggtca gcggaagact ctcccgccag aggaagacgg acgggaccat
    16441 gtactccggc agcaactcgc ccagccggcc ccggaggaca tcggcctcca gcgcgtgccg
    16501 gccggagtag aaggccacca ggcgtttgcc gtgtcccgcc cgctgggtga ccaccaccgt
    16561 gccgtcaccg actccgggca cccggagcag ggcgttctcg atctcaccca tctcgatacg
    16621 gaaaccccgg atcttgacct ggctgtcccg gcggccgagg aactccagct ttccgtccgg
    16681 gagccagcgt ccgtggtcac cggcccggaa gagccgctgc cccggacggt gcggatccgg
    16741 cacaaaggcc agccgggtgc gctcagggtc gttgatgtac ccgcggccca cgcagacccc
    16801 ggagaagacg atctctccgg gggcgccgag cggcaccggc gccaggtgtt cgtccacgac
    16861 gtacacccgc acattgttga cggggcgtcc gagcggcacc cgctcggtgt ccggcacccc
    16921 gtccatcacc tcgtggtggg tgtcgtccga ggtctcggtc agcccgtagg cgttgaccag
    16981 atggatcccg ggccgggccg cgaaccagcg ctgcaccagc tccttcttca gcgcctcccc
    17041 ggtgaccgac acacaccgca gatccggcag cgcgccgggc cgctgcgcga gggcggacag
    17101 cacgacatcg aggtacgacg ggaccacctg gagcaccgtg gcccctccct cgcccaccgt
    17161 gtcgaggaaa cgtcccacgt ccagcacggc ggcctgctcg accagcaggg tccggccgcc
    17221 gaccagcagc gccgagagca gctgccacag ggagatgtcg aagcactggg gcgcggtctg
    17281 ggcgaccacc tgcccctcgt cgatcgccag gtcatcgatc ttggcgtaga ggtggttgag
    17341 catgcccagg tgctcacaca tcgcgccctt gggctcaccg gtggagcccg aggtgaagta
    17401 gatgtacgcc aactggtccg ggccgacccg gacctcgggg tcgctgtccg cggggctcgc
    17461 cgcgcagacg gcgtcgatga agagggtccg gaccccgggc accgaggcga gggcccggtc
    17521 gagaccggcg gtgctgccgg gttccgtcag cacctgccgg cacccggcgc gcgagagcat
    17581 cagcgcgatc cggccgggcg gaaagtgcgg ctccaccggc aggtacaccc cgccggcctt
    17641 gaagatcgcg atcaccgcgg ccagccactc cagattgcgt tcggtgacca ccgcgacgac
    17701 gtcttcccgg cccagcccgc gggccaacag ggcgtgcgcc aaccggttgg cgcggacgtt
    17761 gagttcccgg tacgtccacc gccggctccc gtgtacggcg gcgatggcgt ccgggtgcgc
    17821 ccggacccgc tgctggaaca cctcgtggaa ccggcggtcc ggcagcggcc ggctcggtcc
    17881 ggccagtcct tcgagctgac accggagttc ctcggcggag agcagggact gccgccggtg
    17941 ctcggcgtcc ggatcggcgg cgagcagcgc gagcgccgta cggtagtagc cgccgatccg
    18001 ggcggcgcag tccgcgtcga ggacctcggt ccggaaccgc agccgcagca cctcccggcc
    18061 gtcgtggcgc acgagggcga cccacagcac ggtgtcaccg accggaccgc cctccgcacc
    18121 gggcaggtcg aacacggtct ccgggtcccc ctcggccgga gccggttccg gcccggatcc
    18181 ggcggccggg aagccccggc gccgcaacag ctccacctcg gcccggtggg tgtccagcag
    18241 gagggtccgc caggagccgg ccgcggtcgt cagccggcac ggcagcggag tgccgccccg
    18301 ctcggcgagg tagccggtcg tgacctcgtg gtcgccggac agcacggcca gcaccttggc
    18361 gtgcgcggcc agcagcaccg aactcagcgg catccgcagc cggtcggcca gccggcgcag
    18421 ggtggccggc aggtgttccg gaagggccgt cgtgtgctcg gcggtccccg gaaccgggat
    18481 gcgggtccag cgcggaaccc tggtgtacgc gccgtcggcc gacccaccgc gatcgcggcg
    18541 ggtgtgggct gtcatggatg tggtcatagg ctcctacctc cagccctcgc cggtgtcctg
    18601 gccgcaggtc tgccgggccg gattgccgcc ccagtgcgta tgcggcggga cggcctcgcc
    18661 cttcatgagg aaggagtcgg gcgcgagcac cgcgccgtca cccatggcca cgccgtaatg
    18721 gacgaaggcg ccgacgccga gcgtgcagcc cgcgccgagc gtgctgcggt cggatttgaa
    18781 ggtgccgtcc tcctgcgagt ggcactggac gacactcccc acgttgaggg tgcagccgtc
    18841 cccgatggcg gccagggtcc gctcggtcag atagcagccg tcgtcgaaga ccctgcggcc
    18901 gatccggacc cccagcaacc gccagatcag gttcttgaac ggggtgccgt tgaagaacag
    18961 cagataggtc tccgagggca ccttccagaa gcgttcccgc cgccagaaac gcggatcgta
    19021 gatcgagcag aacagcgggc tcaggggatg gaacgccgtc acggcccgtt cgaccagcac
    19081 gaagtagacg acaccggaca ccagcaccag gacgttgccc agcgcgatcg ccaaggcgcc
    19141 gagggagtca tagagctccg cggcgacggc cacgagcagg gtgacccaga agaaatagag
    19201 ccagcgcacc aggaggtaga gcgccatggt ggcggcgttg tgccggttct tggcggtgag
    19261 gtggcggcgc agctgctcgc cgctcttcaa ctggtcgaag gtgctgtccc gttggaccga
    19321 acgggggatc tcgaagctgg gcgagccgag gagcccgacg ccctcccgga cctcgccgtc
    19381 gaccgggacc atgaccttcg tcgcgagcag gcagttgtca cccgtcttcc cccgcgaggg
    19441 gtaggcgatc cggttcccga ggaagttgcg tggcccgatc gaggtccggc agacgcggaa
    19501 ggacgtgtcc gagaagtcgg cgttcatgac ggacagaccg tcggcgacca tcgtcccgct
    19561 cccgacggaa ctcaggtacg gggtctcgtg cttgacctcg gtaccgaagt tcgacccggt
    19621 ctgttcgatc cgggagaggt cgtagccgag gccccgcagg tagtgcacga tggcggagct
    19681 gtcaccgaac agccgcatca ggaacttccg gttggtggtg agagcgatca gccggtgcac
    19741 cgcgtagtgg aagccgtaca gcggatagac cctgcccggt gtgatggtcc ggctgagcag
    19801 ccgggggacc gtggcctgga agagcagccc gagcggcacg gcggcgaaga agagcaagga
    19861 cagcaacagg gcgtccatgt agaacgtccc gtcgcccagc gccgtggggc cgggctccag
    19921 gaccgcggtg agctgcggcg cctcggccag caggatgccc acaccgccga ccgccagcgg
    19981 cacgtacagc agcagcacgg tcaccaactg gagtgcgctg tgcaccgtcc tgcgcaaggc
    20041 accgcaacgg gccggcccca ccacgcggta gtccacgtcg gtccgctgtg ccggcgatcc
    20101 gtgccagtgt tcgccgtccg gcaccacctg cccgctgtgc agcgacgagg catggccgag
    20161 ctgcgccccg tcacccagcg ccgtctcgat gtcgagcacc gtggcctcac tgatgaccac
    20221 gttcttgccg aggaccaccg tgcccgtctg catcagaccg gcctgtgccc ggtagcagtt
    20281 gaggaacgcg tccttacgga tgacggtgcc gtcgccgagg gccagcagat ccgtgcacac
    20341 cggcacattg cgcgagaaga ccgtgacgcc gcgcccgatt ttcgcgccca gggcccggag
    20401 atagagcgtg tagagcggcg aaccgacgaa cagcaccagc gggttcgcgc ggatcagcgt
    20461 tttgacgacc cagaagcgga ggtacggcag gctccagacg cggaactgct ggggcttcca
    20521 ccggccgatg aggacccact tcaccaggat cggaagggcg cacagcaaca gcagaccggc
    20581 cgtgccgcac agcaccgagc gcagatatct gccgaacatg ccggacccgg cggcgatcca
    20641 ctcataaccc caggccgtgg cgaccgcgac gagggaggtg tacccgagga acgtcagcag
    20701 ttgcagcgct ccgcacagga cgtaccgaga ggtgcccctg acagcgggag ccggcgccga
    20761 cgggggagtc ggtgccgggg gcggggtctc gaccgggaag gacggtgggg agcccgccaa
    20821 cgccgtggcc agcgcccgga tcgtgggata ccggtagatg tccttcatcg acaccggcgg
    20881 caggtcggca cgcttcctga cccgcgcaca gaaatgtgcc atcaccaagg agtcggcgcc
    20941 caggtcgtcg aagaaattcc ggtccaccgg cgtctgcccc gtacccatga cctcggccag
    21001 cgtgacggcg aaggcggcct cgacaccggg ggccggaccg tccgcgccgc accggccggc
    21061 cggggattcc tccggatacg aggtcagttc ttcgaccggc tctccgacca tggcgacctc
    21121 cctgacaagc gccgacgacc gtcgtcccgt caccgggtcc cgcaggcgct cgatgggcgt
    21181 cgcacgggca gttcctaatg tgtattcgag gcccgtacgg gtgtggattg caccaaatgc
    21241 ccattttctc ctgcggggat ctccccgttc ccttacgcaa gagctccgca gcggggatga
    21301 cctgctgctt cggccccttg gagacccggt ctacggacgt cgtccacatc ccgcacgcca
    21361 tggcgcgccg agcggcacgg tgcgcgcgcc aggagggcgc ccgctcagcc gaacgggccc
    21421 cgaccggctg cggtccgcgt gagggaacgt cagcctggga gggcgcggcc ggtacgtggc
    21481 aacgcgtccc gccgcgctcc atcccgggga accgggccgc accggactga cgaggggacg
    21541 gtcgacacgt cgtgaggcgc atttcgcaca ccgcacccga ggggccccgg ccgccggagc
    21601 ggtctgccgc ggaccgtcac gtggacgatc tgctcgtgcg ggtcgcccag ggtgacgagc
    21661 gtgcgttcgt cggcgtgtac gacgccctcg tggtgcccgt catgggcttg gccgctcgga
    21721 tcctgcgcga tgaggcgcag gctgaagagg tggctcagga cgtgatgatc gaggtgtggc
    21781 ggaaggccga ccggttccgc cccgagcgcg gtgccgcgaa gtcctgggtc ctgacgctgg
    21841 cccaccggcg agcggtggaa cgggtgcgat cggtgcgggc cggcgcggaa cgcgagcgga
    21901 aggccgcgca gctggcccac cagaccccgt tcgacgaagt ggtggaggcc gtggaggagc
    21961 gggaggaacg ggcgcaggtc taccgctgtc tggccggcct cgggaacacc cagcgcctgc
    22021 cgctggtcct cgcctactac cagggaatga cctacgcgga ggtcgccgag gccctgtcca
    22081 cccccgcggg cacggtcaag acgaggatgc gcaccggcct gcggagactg cgcgtctgta
    22141 tgggaggcga ctgatgtctg ctgccgagga tccgcacgag gcgctcgggg cgtatgtcct
    22201 gcacgccctt ccgcctgagg aggcggccgc cttcgccacc cacctggccg gctgcgacgc
    22261 ctgcacccgg gaggtcgccg acctggaggc caccgtcgcg tgtctggccg aagcggaagc
    22321 ggtcaccccg tccgacgcgc tgcgccggcg ggtcctcgaa cggatcgcga ccaccgccca
    22381 ggaacagctg ctccgccgcg agccgtcccg gcgcgagggg ccgcgactgg acctggaggt
    22441 ctgacccgcc gcgacggccg tacgcgcggc tcgcgatccg acggccgagc ctcccgtggc
    22501 gccgggcagt gtggtccgac cacacgtcct gtgtgacata gtttttgcac gggggcatga
    22561 gggccgagcc ggggagttgg ggatgaccgc cgaatggcga cctgtgcggc agtcgcgtac
    22621 gcatgagctc gtgctggagc gcatcgaaga gcgggtgctc gccggtgagc tcaaggccgg
    22681 ggaccggctg ccgcccgagc gcgagctggc gccggtcctg ggcgtcagcc ggtccgcgct
    22741 gcgcgaggcg ctgcgggtgc tggagacgat cggagtgctg gtcgcccagg ccgggcgcgg
    22801 gccggacgcc ggggcgcgga tcgtacgcaa cccggacgac gcgctgggcc ggctgctgcg
    22861 cctgcacttc gccctgggca gttaccgtct gcacgatgtg ctggaggccc gggtggtcct
    22921 ggagcgctcc agcttcgagg cggccgcgga gcacgcctcg gcgcaggacc tcgacgaggc
    22981 ggaagcgctc ctggagcgga tgcgcgagcc cggcgtgggg gccgccgact tcaatgacct
    23041 cgacacccgg ttccatgtcg ccatcgcgcg cagctcgggc aaccagctga cctccaccct
    23101 cacctcggcc gtacgggagt cggtgcgccc gctgatcctg cgggcgctgg agacggcgga
    23161 ggactggccg gccacggcgg cggcgctgaa cgccgagcac accgagctgc tgcgactggt
    23221 gcgcgccggc aagggagcga aggccgccga tctggcggag gcacatatcc gtggtttcca
    23281 cggccggctg gtcgacgaga acgccccggc ggagcaggag caggagcaag gggacgaggg
    23341 ccgggcgggc acggaccgct gagcccgccc ggcctctccc gtacgcctac ggcagcatcc
    23401 aggacagcac cggcagcgac tggagataga ccagcacgca caggaccgcc agcatcgcga
    23461 cgctgtagcc ggcgaccttg cgcagcagga tccgctcggt gccgggccgt tccaccgcgg
    23521 tcgccgcgat ggtcaggttc tgcgggctga tcagcttgcc gaccacgccg cccgtggtgt
    23581 tggcggccac cagcagggtc gggtcgatgc ccgcggtctt gccggcggtc tgctgaaggg
    23641 tggcgaacag cgcgttcgac gaggtgtccg agccggtcac ggcggtaccg agccagccga
    23701 ggacggggga gagcagggcg aagagcccgc ccgcggcggc gagccaggtg ccgatggcga
    23761 gggtctgccc cgactggttc atgacgtagc tcagggccat cacggtggcg accgtggcga
    23821 tggcggtgcg catgttgcgc agggtgcgca cggcgcagga cagtcccgtg cgcgcggtca
    23881 tcgggaagcg gtcggcgtcc ttcgcgcggc tgtagatcag catcaccagg agcccggaga
    23941 gcagcagcag ggtgccggga ttggccagga cctccagctt gtagacggcg ctgcccgcgg
    24001 gcgagccatc gggggcgagg aggtggccgt acaggcccgg ccagtcgagc tggagggtga
    24061 gggagccgag cagcccgggt atgtcgagtc cgccgacgtc gagcttggcg agcgcgaaga
    24121 ccgcgatcac caggagatac ggcagcacgg ccaggaaggt gcggcggcgg gtcagcggtt
    24181 cggccgtgac ctgggagcgc tggtcgtccg gtgtcgtggg ggtccagaag cgcagcatga
    24241 ccaccgcggc cccgaagccg gcgagcgcgg cgacgacatc ggtgagctcg taggcgaagt
    24301 gggccgagca ccagaactgg gccagggcga agacggcgcc ggtgaccagg gcgacgggcc
    24361 acagctgccg cagaccgcgc cggccgtcga cgaggaagag cagcagctgc ggcacgaaga
    24421 gggcgagcag cgggctctgc cggccgatga ccgcggcgag ggactccgcg gggatgccgg
    24481 tgaggttgcc cgcggtggtg atgggaatgg ccatggcgcc gaaggcgacc ggcgcggtgt
    24541 tcgcgaccag gacggtgacg gccgaggtga gccggggcag tccgagcgcc atcagcatgg
    24601 cggcggtgat cgcgacgggc gcgccgaagc cggccagggc ttcgagcagt ccaccgaagc
    24661 agaacgcgat gagcatggcc tggatgcgca gatcgccgcg gccgacggcg ttgaaggagc
    24721 ggcgcagatc gtcgaaacgg tggctgacca cggtgagttc gtagaaccag atggccgaca
    24781 cgacgatcag catcaccggg aagagcccga aggccgcgcc ctgggtggcg gacagcgcgc
    24841 cgagccgcag cggcatgccg aaaccgagga ccgcgaccag gagcgcggtc agcagggcgc
    24901 cgagggcgga gtgcagcgcg gagcgcttgg ccgccatcaa cagcaggaag aaggccgcca
    24961 ggggcaccag gcccagtagc gcggtggtgg tgaggctgtc cccgacggcg gccacgtcgg
    25021 gggtgtaggc cgccagggca gcgggcggag tggtggccac ggagtgctcc tcatcgagtt
    25081 ctgcgcgccg tccggccggt ggtgaacgtc cggttccggc catcgcggcg ccgtgtggct
    25141 gacgatcggt cctcagtagc ccaccgaaga tgtcgcatgt caataaggtc ggaccaaact
    25201 gcgtccttac ttttctctct cggttcgagg ggagtatggt cggaccataa gcgccaggga
    25261 ggctctatgc gcatcgctct cttcgccacc tgtctgggag acacgctctt cccggaggcg
    25321 gtgaaatcca ccgcggtact cctggcccgc ctgggccatg acgtggtctt cccgccgcag
    25381 cagacctgct gcggccagat gcatgtcaac accggctatc agcgggaacc ggtgccgctg
    25441 gtgcggaact tcgccgaaca gttcggcgat ccggcgatcg aggccgtggt ggtgccgtcg
    25501 ggctcctgcg cgggctcggt ccgtcatcag cacgagctcg tcgccgaacg ctacggggac
    25561 gcggccctcc gcgccggtgt ggccgccgtc cggaccaaga cgtacgagct gtccgagttc
    25621 ctcgtcgatg tcctcgacgt gacggacgtc ggcgcgtact tcccgcaccg ggtgacctac
    25681 caccccacct gtcattcgct gcgcatgctg cgggtcggcg agaagccgct gcggctgctg
    25741 cgtgccgtcg agggcatcga cctggtggag ctgcccgagg ccgacgcctg ttgcggcttc
    25801 ggcggcacct tcgcggtcaa gaacgccgag acctccaccg cgatgctgcg ggacaagatg
    25861 gaccacatca ccggcaccgg cgccgcggtg tgcacggcgg gcgactcgtc ctgtctgatg
    25921 catatcggcg gtggcctctc gcgcatcagg tccggtacgc ggaccctgca cctggcccag
    25981 atcctcgccg ccacccgcac cgcgccgcac gtcctgacgg aggccgcccg atgagcagtc
    26041 cgaccggccc cgcgacgcgg ggcaccttcc tcggtatgcc ggccgtcccc ccgcgctccc
    26101 cgtacgggac gggccatctg cgcggagagc acagcttccc ccgggccgct cacgacgagc
    26161 tgggcaatga gcaactgcgc cgcaacctgg gcaaggccac ccactccatc cgcgccaagc
    26221 gcctcgccgt caccggtgaa ctgcccgact gggagcagct gcgcgacgcc ggctcggcga
    26281 tcaagaccga caccatgaac cggctgcccg aactgctgga gcagctggaa cggaaggtca
    26341 ccgagcgcgg cggcaccgtc cactgggccc gggacggcgt cgaggccaac gagatcgtca
    26401 cccggctggt gcgggagacc ggcagtgacg agatcctcaa ggtcaagtcg atggccacgc
    26461 aggagatcgg cctcaacgag catctggcga gccaggggat cgcggcgctg gaaaccgatc
    26521 tggccgagct gatcgtgcag ctcgccgacg accggccgtc gcacatcctg gtgcccgcga
    26581 tccaccgcaa ccgcgaggag atccgggaaa tcttcctccg gcacatcccg ggcgtcgacc
    26641 ccgcgctgga cgccgacccc gcccggctcg cggccgcggc gcgcgcgttc ctgcgcgaga
    26701 agttcatgac ggccaaggtg gccgtctccg gcgccaactt cggcatcgcc gagaccggca
    26761 ccctggccgt ggtcgagtcc gagggcaacg gccggatgtg tctgacgctg cccgagacgc
    26821 tgatcaccgt catgggcatc gagaaggtcc tgccacgttt ccaggacctg gaggtcttcc
    26881 tccagttgct cccgcgctcc tcgaccggtg agcggatgaa cccctacacc tcgctgtgga
    26941 cgggcgtgac accgggcgac ggcccgcagg agttccatct cgtgctgctc gacaacgggc
    27001 ggacggcggc gctcgcggac cggatagggc gcgcggcgct ccactgcatc cgctgctcgg
    27061 cctgcctcaa cgtctgcccg gtctacgagc ggacgggcgg ccatgcctac ggatcgacgt
    27121 accccggccc gatcggtgcg gtgctcactc cgcagctggc cggaatgcac ggcgccaaga
    27181 acgatcccaa cagctcgctg ccgtacgcct ccagtctgtg cggagcctgc ttcgacgcct
    27241 gcccggtgaa gatcgacatt ccgtcgctcc tcgtcgagct gcggcaccag cacaccgaac
    27301 agtccgggac gaccgcggag aagctggcga tgaaggccgc ggccgcggtc atgaagcggc
    27361 cggggctgtt caccgccgcg cagaaggcgg ccggactcgg acggggggcg gcggggcggg
    27421 acggcaccct ctcccacctg cccccgccgc tcaacggctg gagcgacagc cgtgacaccc
    27481 ccgccccgcc caagcagacc ttccgctcct ggttcgcctc cgccgagggc gcggccgcga
    27541 tgcgggccgc ggccgaagaa ggcgcccggc acaccgacga cgatccgcag gaggcatcgt
    27601 gaccgcgacc gcacgggaga cggtgctcca ccgtgtccgg gacgccctgg ccctctccga
    27661 cgggcccgag gtgaccgtcc cccgcggcta tcgcaccggc cgctcgctcc ccgacgagga
    27721 acggctcgcc ctcttcgtcg accggctcgt cgactaccgg gcgcaggtcc gcacctgcac
    27781 cgccgcaacc accgcggcgg tgctcgccga ggtgctgcag gcacacggag cacggaagat
    27841 cggagtgccc ccggggctcg atccggcctg gctgaccggg tacgacgggg agacggtgac
    27901 ggattccgct gacgtgcccg cgccctcgct cgatgggctg gacggggtgg tgacgggctc
    27961 cgccgtcagc tgcgccgaga ccggcacgat cttcctggac ggcgccgccg cggaccaggg
    28021 gaggcgcgcc ctgaccctcg tccccgatct gcacgtctgt gtcgtcgagc tgtcgtcggt
    28081 gcggaccgga gtgccggagg cggtggccca gttgacgccg gagcacccga tcacgctgat
    28141 cagcggcccc tcggccacct ccgacatcga gctggagcgg gtcgaggggg tgcacggtcc
    28201 gcgcacgctg gcggtggtga tccgcaccga ccgctgagcg gctcggcgtc ctccggggcg
    28261 cggccgccct cacgggacgg gccgcgccgc ccgccgccca tgccgctgcg cgcagcagcc
    28321 gcaggccgtt gaggccgacc gccgcggcga gttgcacggc ggccgcggat ggtcaccgga
    28381 agggcctgcc tacaggctcc ggttgtccag taccgccacc gcccgtcgca cccgggcggt
    28441 ctcctcggtg tccacgtccc cgacgagcag gtccggccgg tcacccagct gtccgcgtac
    28501 ggtcccgtcg gggccgatca gcgcgctgtg cccgacaccg gtcggcgcct tggtgggggc
    28561 ctcgggatcg gcctgcggat ccggagcggc ctgattgacc gccgccagcc agaccgtcgc
    28621 gtccaaggca cgtgcccgta cgagcaggtc ccactgtgcg cgcttgccgg gccccgcggc
    28681 ccaggcggcg ggcagcaccg acaccgttgc ccccgcatcg gcgtgggccc ggaacagttc
    28741 ggggaaccgc aggtcgtagc aggtcgccag gcccacccgg accccgtcga catcgatggt
    28801 caccacgcgc ttccccgggg cgaccgcgtc ggactcccgg aacccgaagg cgtcatacag
    28861 atggatcttg tcgtagaact cctcgacccc gggcccggtg gccagcaggg tgttggtcac
    28921 ccgcccgtcg tccgccgggg tgaacatgcc cgccaccacg gtcacgccgg tctcccgggc
    28981 caccgcccgc accccctccg cccacgggcc gtccagcggc tcggccacct gcccgagcgc
    29041 ggccccgaac cgcaccatgg ccgcctccgg aaggaccgcc agccgggcct cctcgcgtgc
    29101 cgcacggcgg acctggtcct ggacgatcgc gaggttctcc ttcggatcgg tcgatgccgt
    29161 catctggcac agcgcgatac gcatgcggat ctcttctctc tcgtgcggtg tcctcagggc
    29221 ctggttccgg cgccgcccgg cccgtctcac cgccgggagc gccggtgacc atcctgcctg
    29281 ccgactgccc ggggccggac gtcagacagg tgcactcctc ctcatcgtgc gccggaaccc
    29341 gccccgggag cacgtccggg agcacgtccg ggaggggtac ggcgatcccg gccccatccg
    29401 gacggcacgg cgggtggcct cctcacggtc ggttaccggg ctgaaatcct gcgtgaggca
    29461 tcccggtgcc ggagcccttc ggcggacggc cgggcgggcc ggtttcagac cgcgctcaag
    29521 tcaccgcccg taccggcgat ttcctccggg cgcagcagtg ccgcgagccg gtcggccggg
    29581 agcagcccct gttccaggac gagttcggcg acaccgcgtc cggtggcgag tgcctccttg
    29641 gcgatcgcgg tggcggcggt gtagccgatg tgcgggttga gggcggtgac caggccgatg
    29701 gagttctgca cgctggcccg gagcgtctcg gtgttggcgg tgatgcccgc cacgcagcgc
    29761 tcggcgaggg tgcggcaggc cgccccgaga tgggtgatgc tctccgagag ggagtgcagg
    29821 atgaccggct cgaaggcatt gagctggagc tggcccgcct cggccgccat ggtgatggtg
    29881 acgtcgttgc cgatgacctc gaaggcgacc tggttgacga cctcggggat gaccgggttg
    29941 accttgccgg gcatgatgct cgaaccggcc tgcaccggcg gcagattgat ctccgcgagc
    30001 ccggcgcgcg ggccggagga cagcagccgc agatcgttgc agctcttcga gagcttgacg
    30061 gcgatgcgct tcaggacgcc cgacagatgg acgaaggcgc cgcagtcctg ggtggcctcg
    30121 acgaggttgg cggcggtgac cagcggcagc ccggtgaggg cggccagatg ggtgcgggcc
    30181 gcctcggcgt agcccttggg ggcgttgagg ccggtgccga tggcggtggc gccgaggttg
    30241 atctcgtgga tgagcaggac cgcctcggcc agccggctct ggtcctcctc cagcatcact
    30301 gcgtacgccg agaactcctg gcccagggtc atcggcaccg cgtcctggag ctgggtgcgc
    30361 cccatcttga ggatgtcgcg gaactcctcg gccttcgccg cgaaggccgt acgcaggacg
    30421 gtcatcgagt cgagcagttc ccggacggcg atgatcgtgg cgacgttgac ggcggtcggg
    30481 tagacgtcgt tcgtcgactg gctcagattg acgtgctcgt tggggtgcag atggcggtag
    30541 tcgcccttct catggcccag gatctccagc gcccggttgg cgatcacctc gttggcgttc
    30601 atgttcgtcg aggtcccggc accgccctgg atgacgtcga cgacgaactg gtcgtgcagc
    30661 tgtccgccgg accggatctc ccggcaggcg gcggcgatcg cgtcggcccg ctcggtgtcg
    30721 agcagtccga ggtcctggtt ggcccgggcc gcggcctcct tgacggcggc gagcgcattg
    30781 atcaggtgcg ggtaggtggc gatcggcgta ccggtgatgg ggaagttctc cacggcgcgc
    30841 agggtgtgca cgccccagta cgcctcggcg ggtatctccc ggtcgccgag cagatcgtgt
    30901 tcgcggcggt ggccggcgga agtcatggtg cagcgggtcc tttgtgaggt ggagcggagg
    30961 gggagggggc cgggcgggtg agcccggcgg agaggtgatg gagcgtcagg tcacttacgg
    31021 agcaagggtg tccgccgccc gcagcgcccc gaccggggtg ccgcccccga tgacgggtgt
    31081 ggtggcgaac ggggcgagga cgccgggatc gatgccgcag cgcgccaggg ccgccgcggt
    31141 caccggcatc cgggcgcggt caccgccgtc ggcgatcttc acgccgaccg cccgcccgtc
    31201 cggcagggcc gcgatctgca cgccctcgaa gccgtccttg gcgagcagac ccggcaccgc
    31261 ccgcaccagc cgggcgacgt cccgccggct gccggacacc atctccgggt gcgtgcgcat
    31321 ggcgtgggcg acccggccct cctcactgcc gggcgcggcc gtcgccagcc gggcggcggc
    31381 ccgggtcagc ccgtggaggg agacggagaa cagcggggcg ccgcagccgt cgaccgtgac
    31441 ccgcgcgatg ccctggccgg tgaggtcttc gaccgtcgcg gcgagttccc gctgcaacgg
    31501 atggccgggg tcgaggtagc tgtccaggtc ccagccgcgg gcgcggcagg tcagcagcat
    31561 ggcggcgtgc ttgcccgagc agttctgtgc gagccgggtg ggccccagac cgcgccggat
    31621 ccactcgtcg cgtacggcgg ggtcgtacgg cagatcgggg acgttgcgca gctcgtcctc
    31681 ggtcagctcg ccggcggcca ggatgtcccg ggccgtggcc agatgccggt cctcgccgga
    31741 gtggctggcc gcgaccaggg ccagcgacgg atcgtccagc ggcggcaggc ccgcgcgcag
    31801 caggccgacc gcctggaccg gcttgagtgc cgagcgcggg tagaacgcgg cctcgatgtc
    31861 gcccgcctgg aatgccacgc tcccgtcggc cgccagcacc acgacggagc cgtggtggac
    31921 gccctcgacg atgcctccgc ggaccacatg ggcgacgggg acatgggccg gttcgcggac
    31981 cgcgggcggc gcgcccgcgg tccggtgcgg cggcagggtg gtgctctgac tcatgatcag
    32041 ttctcggtgc tttcggtgcc gtgggggttg tctgtgccgt gggtgttttc ggtgtgctga
    32101 gcggggggtg cggtgtgcgg gtgcgcgccg ctcgcctgcg ccgccgcggc gtcctggagg
    32161 atgccgaccc ggcgccgtac caggaaccag ccgccgacca gcgcggccac gatcagcggc
    32221 agcgacagca cggtggtgcg gccggctccg ccgtcggccc acatcaggac caggaccagg
    32281 gccaggaagg ccagcgtcac gcactcggtc cacggcgagc cggggagccg gtagctgggg
    32341 cggatgagct gtccggcgcg cgccttccgc cagaagagca gatgacagag catgatcatc
    32401 gaccaggtgc tgaggatgcc gatcgccgcg aagttcagca cgatctcgaa ggcctcgctc
    32461 ggcacgacgt agttgaggcc cacgcccagc acacagaccc cggaggtgag cagaatgccg
    32521 ccgtacggga cctggctgcg gctcatcacg ccggtgaacc gcggcgcgga gccggacatc
    32581 gccatcgagc gcagaatgcg cccggtggag tagaggccgg agttgaggct ggacatcgcg
    32641 gcggtcagca cgacgaggtt catcacaccg cccgcggccg gtatcccgat cttggacagc
    32701 acggtgacga aggggctctc cccggccgag tacgcgctcc agggcagcag catcgccagc
    32761 aggaccaccg agccgacgta gaagacggcc acccgccaca tgatggagtt gatcgccttc
    32821 ggcatgacct tctccggctc cgcggtctcg cccgccgtga caccgaccag ctcgaccgac
    32881 gcataggcga acaccacacc ctggatgacc agcagcatcg ccagggtccc ggtcgggaac
    32941 acgccgccgt ggtcggtgac cagcgagggg ccgggggagt ggccggcgac cgggtgctgg
    33001 gtgaccagca ggaagatgcc gatcagcatg aagacgacca gcgcgccgac cttgacgatc
    33061 gcgaaccaga actccagctc gccgaagatc ttcacggaga tgagattcac ggtcagcacg
    33121 accgcgagcg cgatcagcgc gatcacccac tgcggtatct cggagaacat gccccagtag
    33181 tgcgtgtacg tcgccaccgc cgtgatgtcg gcgattccgg tggtcgccca gttcaggaag
    33241 tacatccagc ccgcgacgaa cgcgcccttc tcgccgagga actcccgggc gtaggacacg
    33301 aacgcacccg aggacggccg gtgcagcacc agctcgccca gcgcgcgcac caccaggaag
    33361 gcgaacaggc cgcagagcgc gtacgccacg gccagcgacg gtccggcact ggcgagccgg
    33421 ccgcccgcgc cgaggaacag cccggtgccg atggccccgc cgatcgcgat catgttgatg
    33481 tgccgggagg tgagggactt ctggtagccg gcgtcaccgg cgtccacatg cccgcccgcc
    33541 tgctgatgcg cgtcctgtga ggcgctctgt tgttgctgcc gttccgcctg ccggagggat
    33601 tgctcgctca cgcgtgatcc tcgtcttccg tggaggggtc cgtgcggtgt tgcgaccgca
    33661 cgatggtggt cagcgtcgtc tcgacgcggg cgaggtggtg cgccatggct tccaccgcgt
    33721 cgtgttcgga gcggtcgacg agtgcctcga cgatcgcccg gtgttcccgg ttcgactgct
    33781 cgcgccggcc gccgagctca ttgaggaagg ccgactggcg ggccagcgca tcgcggatct
    33841 cctcgatgac ccggcggaag accggattgc cggccgcctg ggcgatggcg agatggaaga
    33901 ggctgtccat cgccacccac gcggtggtgt cggtctcctg ctccatccgg tccagcagat
    33961 ggttcagctg atcgaggtcc tccgccgtgt ggcgcaccgc cgcgtaaccg gccaccggga
    34021 tctccacatg gcggcgcacc tcgagcaggt cgctcgccgc gtagtcgccg aaggtcgggt
    34081 ccgccacggc gccgtcggag atgacgaagg tgcccttgcc ggtgcgcgag accgtcagcc
    34141 ccatggtctg gagcgcccgc agcgcctccc ggagcacggg tctgctcact tccagccgtc
    34201 ggcagagctc cgcctcggag gggagcttgt ccccgaccgc gtactcgccc cgctcgatgg
    34261 cgccgcgcag atggttcagg accgcttcca tcgcgctgat ccgccggggc atctcgccag
    34321 ctgtctggct gtctgacagg ttcaccccgg gatcgtcgat tccagccggg ggagctgtca
    34381 aggggtgcgg cgcagatcat cctcggatcc gggcccggac ccgggagtcc cgcgcccctc
    34441 cctcccgatg tcgttccgct ccgtgccgga tccgctactg cgggtgcggc cattccccgt
    34501 cgtgccgtcc gtcgccgcgg aagtccagca tgtagaagac cttgtcgtag cggcgtccgc
    34561 ccatcgccac gaagtcgggc agccggccgt actcacggaa gccgagcgac cggtagaggg
    34621 tcagtgccct ggtgttgtcg gcccgggcgt ccagggtgag gacctcgatc cccgcacccc
    34681 gcgcgtcctc gaccaaggcg ctggtcagcg accgtccgag gccctggcca tgagcctcgg
    34741 aggccaccgc gatcttctcc agatccgcgt gctgccgatt ggtcggacgg gcatagcgca
    34801 gccagtaccc cagcccgacc agccgggggc ccgcgtacgc cgcccgcagc gccccgtccc
    34861 cggtgtgggc ggcacgcacg acacggtcga ccagctccgc cacctcgccc cgtccgggcg
    34921 ggtcgaccca gccgagcggt gcgccgccgc tgaccaggtc cgccaggatc cggtgggccg
    34981 cctcggcgaa gtccgtcgcc cggtccgcgt cggcggccag ctggagggcg tccaggatct
    35041 cgggctcggg gtccattccg ttatgtgtcg tcggattcat gatcggcagc ctagggggcg
    35101 gtcggcgtcc gctgccatgg agcggcggag ggagcaactc cgcctgcggc caaggggtat
    35161 gggagcgccg ggggagccgg ccgggtcccg cgagcgccgg ctgtgcggcg actgcgggac
    35221 ggcgcgcacc gggccggggg cgatcgacgg ggcgcaccgg gccggggcgg tcagtgggtg
    35281 ccggcccagc ggtagcggtg ttcggggcgc ccggtgtcgc cgtatttcag ggtgaggatg
    35341 atgtggccgc tgcgttcgag gtgcttcaga tagcgctggg ccgtggagcg gctgacaccg
    35401 gcgcgttcgg cgacctcgtg ggcggacagc gggtgtccgg acgcgcccag gacccggcgg
    35461 atcaggtcga cggtcgcggc cgagtgcccc ttggggagct cggtgtgcgg ggagtcggtg
    35521 gtccggaagg cgccgaagat ccggtccacc tgttcctggc cggcctcgcc gcggccgcct
    35581 atcccctcga cggtccggcg gagggcggca tagccgtcga gcttggtgcg cagaccggag
    35641 aagccgaacg gtttgacgag atattgcagc gccccggagc gcatcgcgtc ctggaccgtg
    35701 ccgacgtccc gggccgccgt caccatgatc acgtcggtgc ggtggccgag ctgccgcagc
    35761 cgccggacca ggctcaggcc cgtctcgtcg ggcagatagt ggtcgagcag caccagatcg
    35821 acatgggtgc gctccagtgt ggccagcgcc tgggcggcgg tgtgtgcgcg gccggtgacc
    35881 cggaagccgg acacctggga cacatacgcg gcattgatct cggcgacgtg gaagtcatcg
    35941 tccacgacca ggacatcgat catcgtgagg ttccgctccc caagggtctt cgcttccgtg
    36001 actccatgcc ttccgggcgc tccgggcgct ccggacgccg gggcgcgccc cgcaccgagg
    36061 cgtcctccgg ggcgagggcc tcgggcagga cgacggtgaa gaccgcgccg c
//
