LOCUS       NZ_BBNO01000001        21533 bp    DNA     linear   CON 19-AUG-2024
DEFINITION  Streptomyces lydicamycinicus strain TP-A0598, whole genome shotgun
            sequence.
ACCESSION   NZ_BBNO01000001
VERSION     NZ_BBNO01000001.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces lydicamycinicus
  ORGANISM  Streptomyces lydicamycinicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Komaki,H., Hosoyama,A., Igarashi,Y. and Tamura,T.
  TITLE     Streptomyces lydicamycinicus sp. nov. and Its Secondary Metabolite
            Biosynthetic Gene Clusters for Polyketide and Nonribosomal Peptide
            Compounds
  JOURNAL   Microorganisms 8 (3), 370 (2020)
   PUBMED   32155704
  REMARK    DOI:10.3390/microorganisms8030370 Publication Status: Online-Only
REFERENCE   2
  AUTHORS   Komaki,H., Ichikawa,N., Hosoyama,A., Fujita,N. and Igarashi,Y.
  TITLE     Draft genome sequence of marine-derived Streptomyces sp. TP-A0598, a
            producer of anti-MRSA antibiotic lydicamycins
  JOURNAL   Stand Genomic Sci 10, 58 (2015)
   PUBMED   26380643
  REMARK    DOI:10.1186/s40793-015-0046-5 Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1269470)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: Newbler v. 2.6
            Genome Coverage                   :: 93x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000829715.2-RS_2024_08_19
            Annotation Date                   :: 08/19/2024 02:08:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,323
            CDSs (total)                      :: 7,237
            Genes (coding)                    :: 7,092
            CDSs (with protein)               :: 7,092
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 54 of 145
            Pseudo Genes (incomplete)         :: 123 of 145
            Pseudo Genes (internal stop)      :: 9 of 145
            Pseudo Genes (multiple problems)  :: 39 of 145
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:07:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 782504
            Orig. end                         :: 804037
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBNO01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21533
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="triceptide"
                     /region_number="2"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..21533
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="single"
                     /product="triceptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21533
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11533](+)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11533
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
     gene            complement(435..1364)
                     /locus_tag="TU31_RS03425"
                     /old_locus_tag="TPA0598_01_07240"
     CDS             complement(435..1364)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536136.1"
                     /locus_tag="TU31_RS03425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07240"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_042148620.1"
                     /transl_table=11
                     /translation="MSARSEWSQRPVQVAEPRTLEISDPFDALSVRVVGGTVNVVGTSD
                     GSPARVEISELHGPPLTVSCDHGTLSVAYDDLPWKGFLKFLERKGWNRSAVISVTVPAG
                     TRVEVGVVGAGAVVSGISGRTDVRGVSGDATLVGLTGRVQADTVSGNVEVQSVTGDLRF
                     HSVSGDLTVIDGAGGAVRADSVSGDMVLDLDPAQGADIALTTVSGEVAIRLPDPADATV
                     EANTASGTVSNAFDDLRVTGQWGAKKITGALGAGTGTLKVTTVSGGLALLRRPAFEGED
                     PPGGPGGVPAPGPQGDSPTDPPAEKKVL"
     misc_feature    complement(1401..1417)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.09"
                     /tool="antismash"
     gene            1562..1996
                     /locus_tag="TU31_RS03430"
                     /old_locus_tag="TPA0598_01_07250"
     CDS             1562..1996
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TU31_RS03430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TPA0598_01_07250"
                     /product="hypothetical protein"
                     /protein_id="WP_042148623.1"
                     /transl_table=11
                     /translation="MRTSTGLISTLVLGAALSLPVTAAHAAPAEASVSAAAASCHGLIT
                     DAYSLNNKAISASRAGSYKKAAKRNHATEGKIVNALGACRHARHRAEIRRALDAARNDI
                     QGAEHHNKKAYIEHDRRAGRAALNDEYDAQRRLRDAAHYS"
     gene            complement(2113..2295)
                     /locus_tag="TU31_RS03435"
                     /old_locus_tag="TPA0598_01_07260"
     CDS             complement(2113..2295)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603154.1"
                     /locus_tag="TU31_RS03435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07260"
                     /product="DUF6104 family protein"
                     /protein_id="WP_018087464.1"
                     /transl_table=11
                     /translation="MYFTDRGIEELENRRGEEEVTLAWVADQLRTFVDLNPDFEVPVER
                     LATWLARLDDEDEDE"
     gene            2449..2868
                     /locus_tag="TU31_RS03440"
                     /old_locus_tag="TPA0598_01_07270"
     CDS             2449..2868
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087463.1"
                     /locus_tag="TU31_RS03440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07270"
                     /product="CU044_2847 family protein"
                     /protein_id="WP_042148626.1"
                     /transl_table=11
                     /translation="MQDRAQRIELPDGTEVWARVSRLDTPAPDGTDDADGEFEDVGAWD
                     ALGARVEGLREVIGGVAASVRQATERVAPHETSVTFGVELSAKPGKAVALLADGEAKSN
                     LSVTLTWRRADREPSGDAPHGPHTADRREPDDSSR"
     gene            2868..5102
                     /locus_tag="TU31_RS03445"
                     /old_locus_tag="TPA0598_01_07280"
     CDS             2868..5102
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603152.1"
                     /locus_tag="TU31_RS03445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07280"
                     /product="trypsin-like peptidase domain-containing protein"
                     /protein_id="WP_042148629.1"
                     /transl_table=11
                     /translation="MSTSEGRAAGRGDRARYTQLLEHAGRTTVALRAAPGGAAARPWGS
                     GVLIAPGWVLTCAHVLAASDGRRRETGPDGVFGVTFDGRVVPARLAYDLSRPDPAAGPA
                     AVRADLALVQLLDPATEHPCAWLSDQPATLLEDAYIFRGHDASGAVTERDGDAGTVRRG
                     EHAVRDAGDGGDPRDGGPGPGDGPGARGRGEHGAPAGPRAPAPSVDPFIAVRFGARDAR
                     GLQFGSDVRVSPGASGGPLLDCDRGEVVGIVKGRHQQDHVGLAVPVTALRGLGPEHLVA
                     GAEGLGPDPYHALMSLHDRWHWAGQDLGRAVGPTWFDAQHTIMAGRGRLWGVQERLQAL
                     DLLARLPAPRDPLVVEAAVGEVLERGERPGAWLLRTWRDGHGALYQGSDPYTELRAFVH
                     YLRIVAQLTADEVRDAPGEEAAAVREQATRLAEFVQAKAVVLQPQDRRRIGPVRRRPCS
                     VLVEFEPLFYDEGGQELFNWSVSEGYGQGQWLRVDVQESAGGVPFEQAREQVLRRLGGR
                     LLRADGDAGPNARVRLEVAVPEGHWDTAAGQWEVAASTRRTARLRPVGPGRAVILRDQG
                     RREQVDPAWLRRWQGLAAARELQALRIPPRPGADGRSPSAEAIWRLLETAGEGALPALC
                     HAVADGFGRDAVGVALDTGFPAGLWPAHGHGEERDCDAGCEEFHRGVRELLQGSGGVAR
                     LPELVRQLRAKAAEAAEEGTHWARDLVLLYDDPEDPIPPLFTDRPQMSPR"
     misc_feature    complement(5310..5323)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.13"
                     /tool="antismash"
     gene            5451..6506
                     /locus_tag="TU31_RS03450"
                     /old_locus_tag="TPA0598_01_07290"
     CDS             5451..6506
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603151.1"
                     /locus_tag="TU31_RS03450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07290"
                     /product="MoxR family ATPase"
                     /protein_id="WP_042148632.1"
                     /transl_table=11
                     /translation="MSDWLIYRGAGAPHDGIEHLPPPPPWRDFDGGPLVAPPAALDPSS
                     ERRLGVQHREASHHRPGETERELVNAALYLRRPLLVTGAPGSGKSTLAHSVAYELGLGR
                     VLGWPVVSRSTLRDGLYDYDAIGRLQDLQIARAAPATAEGAAAAGPDPTDEPGGGIGRY
                     IRLGPLGTALLPAARPRVLLVDELDKSDIDLPNDLLNVLEEGEFRIPELERLAGSAPEV
                     EVLSDDGTRVTVRDGRVRCRAFPFIVLTSNGERDFPAPLLRRCIHLHIPVPDKERLAAM
                     VRAHFGEGAAERYEAVIDRFLDREPGDVRAVDQLFNAIHLTQRAGWTDEDEEETRRRLT
                     AELMRPLDRTR"
     gene            6512..9895
                     /locus_tag="TU31_RS03455"
                     /old_locus_tag="TPA0598_01_07300"
     CDS             6512..9895
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087461.1"
                     /locus_tag="TU31_RS03455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07300"
                     /product="SAV_2336 N-terminal domain-related protein"
                     /protein_id="WP_245698387.1"
                     /transl_table=11
                     /translation="MPPGEPGPGPLDELVARLTAAGLPADARGMADALWLAQWITPGPS
                     RAEGTTDAGPTHGDPPDRTDSATFRVGPAVSAEFSGTGGTAAAGSGSETADGDPAPAVL
                     QQGARRRVAELLPTRDPGETPARFPDPDRQRLGEVAVPIASAFPGLLPLQRALRPIQRY
                     RPPVAPVPRRLDEPATAELSAHAEMIIPVLRGVHRRAAGLRLLMDGSSSMAVWEQMLHD
                     LRQVCERVGAFRDVTVHYLHPHGPDVGVAAAPGPGRPLRPADQLHDPTGHHLTLVVSDC
                     AGPLWRDGRMQRLLYRWAADAPLAVVQPLPQRMWARTLLPAVAGTLVRRQGPYQALGFR
                     PARRRRRPAGPPGTAEAPRERAIPVLSATPSALGSWARLAAADAGLSLRGAASVVRADH
                     GTELPAGPPPAPGPAAPARMVREFDQQASPAARLLAVHLSAVPLALPVIQLVQRAMLPQ
                     TGPAELAEVLLSGLVTQLPPDERPSGEQAGVSGPWYDFAPGVRDELLARLSAGEAALVL
                     KHCSLYVERTFGRSARNFPAVAVAMLSGSGREPETGQRAVPEPFARVSERVLRRFEPAL
                     RPPARRPYATDGPAAEGAALLERYEQDRAGRDLIEAVRLLRAATERLPVAGTDLARALL
                     HAWATWRQPDALEEAEHAARAAERATAGEPVDDQEGAAAGREAERTRALIVLGRVGHAR
                     ARERRAAGTPAEERTALADAARHLHAACGLMSLLDPRVLESMVLRTEVLRRLAALPPVP
                     STDGATDPDPLDEAERSLTTLLDQWPSGEQVPGEVYAARGGVLLDQARRAAHGDTEGPR
                     PAEALAVRAADDLDTAAVLLRRRGGAADRLVCETLLDLAAARQLNGGAALPSVLPTLEH
                     ARALAHELDDRALEADSLRRTAAAQRAVHTRTGDLTALDAAIAALAAALRLTTPDSPEH
                     SALLAERGAALLLRARLEPAGEPGKRLANEAVHVLREALGRVAPQDPDLGSHRLLFGRA
                     LRLRYERQPSLADLHEADWILELAARGADVPDAVAAEAWLEVGDVQLLLDRRFDSRERH
                     DRAAACYRRAAAAARRADSALPAARAHHRRGEVLEVTAGPRSALHAYRESWEQWQRAGE
                     DTGPEAQRTRARMRALESTA"
     misc_feature    8723..8725
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..10219
                     /locus_tag="TU31_RS03460"
                     /old_locus_tag="TPA0598_01_07310"
     CDS             10001..10219
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603149.1"
                     /locus_tag="TU31_RS03460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07310"
                     /product="YxD-tail cyclophane-containing RiPP peptide"
                     /protein_id="WP_042148635.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTPRTEPAVAAPPGPSAERLPDFAGVDVGVLAARTDHAVLGEV
                     AALLLRNWPSAEDAVAYYEDGPEKVLH"
     misc_feature    complement(10226..10239)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            10379..11533
                     /locus_tag="TU31_RS03465"
                     /old_locus_tag="TPA0598_01_07320"
     CDS             10379..11533
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SAM_SPASM_FxsB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087459.1"
                     /locus_tag="TU31_RS03465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07320"
                     /product="FxsB family cyclophane-forming radical SAM/SPASM
                     peptide maturase"
                     /protein_id="WP_042148638.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.5e-81, bitscore:
                     270.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="SAM_SPASM_FxsB (E-value: 7e-134, bitscore:
                     442.4, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.5e-14, bitscore: 48.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGEKTGPTAVVPFRQFVLKVHSRCNLACTYCYIYAGPDRSWRAR
                     PPAVPAATMRQTALRIAEHARTHRLREVRIDLHGGEPLLTGPGPLLAQAAAVRAALPAG
                     CTAEFGVQTNGTLLTRDMIDTLGAAGFRLGLSLDGGTPGLNRRRIDHAGRPSWPAVSRA
                     VRLLHDRPDVFAGILCTIDVTAAPAEVYDSLRALDPPMVDFLLPHANWTSPPPAPLGPA
                     GRTPYGDWLCTVFDLWWDGGPGPRVRVFTEILGLLLGRPSSSEAVGLSPVVALVVDTDG
                     AIEQVDSLKSTYEGAAATGLDVFRHTFDDALAHPGMAARRSGRDGLGAQCRGCALVEVC
                     GGGNYAHRYRADAGGFTNPSVYCADLERLIRHIAARLDATVALN"
     gene            11667..14678
                     /gene="fxsT"
                     /locus_tag="TU31_RS03470"
                     /old_locus_tag="TPA0598_01_07330"
     CDS             11667..14678
                     /codon_start=1
                     /gene="fxsT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087458.1"
                     /locus_tag="TU31_RS03470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07330"
                     /product="FxSxx-COOH system tetratricopeptide repeat
                     protein"
                     /protein_id="WP_042148640.1"
                     /transl_table=11
                     /translation="MVDQAHFSGPTGSNEHITISYAGFTRPWAAWISHQLEQQGHGTTM
                     LRWDPQVDTALVEELSGLLEAEGRLLMVLDDWYFRLGPKTQDEWTAALREVVSAHADRF
                     AAVSVATQSLPATASLLRPVDLRDLDAHEANRRVLQRLGIAAPGRAVDEDAPGAPRFPN
                     NPPEVWNIPRRNNRFTGRDHVLEALHGKLAGSGAGAGPPLETRLALYGTSGVGKSQIAA
                     EYAHRFGNDYDVVWWISATNRGAAREQLAELATRLGLPVGRELGDRIRAVHEALRVGRP
                     YRRWLLIFDSADDMESIEDLVPDGRGHVLITTLTRDWSGSGSAQEIEVPPFERVESVAY
                     ARRRAPRLTPMEADLLSEAVQDLPLLLAQTAAWLDANPMAPKEYIELIRRGEPSLVGIR
                     ISSDYPMAFQTSWAITLNTLRERSPAAVELLKLFAFFAPDTIPVPMLARARRGDLPEHL
                     ADLAAEPISWNTALRRLTESTAVRLDYQVSQDADPAVETALMHRLYHRFLRSDMTEDER
                     DLMSACACRVLVTADPQNPADTRYWERYAELIPHLEPAGVLDSPEPAVQQLLLNCVEYL
                     RVRGEYRMGLRLCEQFMSRWRTRLAATQRTMLVLTHQHANMLRRLGRYREAEAVGSAVV
                     DQLAAERDPSDADLLRAQDGLAGTLIALGSYEQAYDLFDAVWRAYTELLGPEAPRTLSS
                     RHNLGSVLALLGRYEEALVTHREVLSFRERELRARHHLTLNAGTAYARTLRLLGRYRDA
                     TSSQELNARLHLQVMGAHTPQTLRAEHNLALCLRRSGEVTRAATLLADLVERSRRVLGP
                     RHPETLMVRADHATFLREHGDLGHARDLAEEVAERYRALAGERHPYTVGTLGNVGLVRG
                     EFGDPADALDLAERALSGMAEAMGPGHPWTLGCALNAAAARNRVDDEEGAVELGRDTLE
                     RAKARLGDTHPLTLSAKTALSEDLRALRRGQEAAKLEQEAIQQLSETLGAEHPHTLSAR
                     RRRRPYWDFEPQPV"
     gene            complement(14781..18584)
                     /locus_tag="TU31_RS03475"
                     /old_locus_tag="TPA0598_01_07340"
     CDS             complement(14781..18584)
                     /EC_number="4.1.1.71"
                     /GO_function="GO:0004591 - oxoglutarate dehydrogenase
                     (succinyl-transferring) activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950819.1"
                     /locus_tag="TU31_RS03475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07340"
                     /product="multifunctional oxoglutarate
                     decarboxylase/oxoglutarate dehydrogenase thiamine
                     pyrophosphate-binding subunit/dihydrolipoyllysine-residue
                     succinyltransferase subunit"
                     /protein_id="WP_042148643.1"
                     /transl_table=11
                     /translation="MSLQSPNSSSISTDQEGQGKNPAAAFGPNEWLVDEIYQQYLQDPN
                     SVDRAWWDFFADYKPGGATAPGQAAEGAAPAPAAPAQSAAPAAEPKPAAAAPATPAKPA
                     ASAPAPAKAAPAKAAPAKAEPAKAAPAEPAAKPAAEEGSAPAGPEFITLRGPSAAVAKN
                     MNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKVSFTHLIGYAMVQALKAMPS
                     MNHSFAEKNGKPTLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLTFFEFWQAYED
                     IVRRARDNKLTMDDFTGVTASLTNPGGIGTVHSVPRLMPGQSMIMGVGAMDYPAEFQGT
                     SQDALNKLGVSKVMTLTSTYDHRVIQGAASGEFLRIMSQLLLGENEFFDDIFKSLRIPY
                     EPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYHQRKHPDLDITEHG
                     LTLWDLEREFAVGGFSGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVE
                     RSHKSPEREEQLRILRRLNSAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAE
                     SRLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTF
                     TGLDGEQIKVSLTANPSHLEAVDPVVEGVARAKQDIINKGGTDFTVLPIQLHGDAAFAG
                     QGVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHV
                     NGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKR
                     SVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTEVRDATTAPVAPEVPQPKAEFP
                     VYVDTAISQEVVKRIAESQVNIPERVTVHPRLMPQLQRRAAQVEDNAIDWGMGETLAVG
                     SLLMEGTPVRLAGQDSRRGTFGQRHAVLIDRETGDDYTPLLYLSEDQARFNVYDSLLSE
                     YAAMGFEYGYSLARPEALVMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPH
                     GYEGQGPDHSSARIERFLQLCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPK
                     SMLRLKAAASRTDEFTSGGFRPVIGDSTVKPEDVRKVIFCSGKVYYDLEAEREKRGAND
                     TAIVRIERLYPLPGKELQAEIAKFPNAEKYLWTQEEPANQGAWPFLGLNLIDHLDLAVG
                     ADVPHGERLRRISRPHSSSPAVGSAKRHQAEQAQLVAEAFDA"
     gene            complement(18822..19946)
                     /locus_tag="TU31_RS03480"
                     /old_locus_tag="TPA0598_01_07350"
     CDS             complement(18822..19946)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469763.1"
                     /locus_tag="TU31_RS03480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07350"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_042148646.1"
                     /transl_table=11
                     /translation="MTRSPRTRLTELWQRVWEGLRPLDPYRSVKAALGALVSVSVIITT
                     LLVFVAMHSATELRVITIFSIIASLLITQFVANSLTAPLDEMTDVTRSMAHGNYSRRVR
                     SERRDEFGDLANAFNRMAADLEAVDTHRKELVANVSHELRTPIAALRAVLENVVDGVCE
                     PDPETMRTALKQTERLGRLVEHLLDLSRLDNGVVPLHARRFEVWPYLSGVLKEANMSRG
                     AATLAGVAGSGTHTRTDVHLHLDVSPPELTAHADAERLHQVVANLIDNAIKHSPRHGRV
                     TVHARRGEGPQSLVLEVQDEGPGIPEAERYRVFERFNRGGPAPSGPGSDGGTGLGLAIA
                     RWAVDLHGGRIGVAESSRGCRIRVTLPGLESARS"
     gene            complement(19943..20683)
                     /locus_tag="TU31_RS03485"
                     /old_locus_tag="TPA0598_01_07360"
     CDS             complement(19943..20683)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536131.1"
                     /locus_tag="TU31_RS03485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07360"
                     /product="response regulator transcription factor"
                     /protein_id="WP_042148648.1"
                     /transl_table=11
                     /translation="MDQTQTTQGGAAAATPGAQRRVLVVEDDPTIVEAIAARLRAEGFQ
                     VQTATDGPAAVDTAEAWQPDLLVLDVMLPGFDGLEVCRRVQAQRPVPVMMLTARDDETD
                     MLVGLGVGADDYMTKPFSMRELAARVHVLLRRVERAALAAHTPRSGILRLGELEIDHAQ
                     RRVRVRGADVHLTPTEFDLLVCLANTPRAVLSREQLLAEVWDWADASGTRTVDSHIKAL
                     RRKIGAERIRTVHGVGYALETPAA"
     misc_feature    complement(20694..20707)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.54"
                     /tool="antismash"
     gene            complement(20757..21509)
                     /locus_tag="TU31_RS03490"
                     /old_locus_tag="TPA0598_01_07370"
     CDS             complement(20757..21509)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611315.1"
                     /locus_tag="TU31_RS03490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_07370"
                     /product="spermidine synthase"
                     /protein_id="WP_042148650.1"
                     /transl_table=11
                     /translation="MAPVTPTQARTGAPEAPRTLDRREGPYGEVVLRQRGGPGTDGPGT
                     PAAPVIYEIIANGCFLMDTSDGRSERLLIDAALDALPAGRAHPSVLIGGLGVGFSLARA
                     ARQPRWGRIVVVEREEAVIDWHRTGPLSAVSADALADPRTGILHTDLVAHLRTEAVRDT
                     YDALCLDIDNGPDWTVTEDNDSLYSPDGLAACRDRLTPGGVLAVWSAQPSPAFEEALRN
                     AGFSGVHTEEIPVVRGVPDVVHLARKGA"
ORIGIN
        1 ccgttcgccg gtccgccatg cctttccgga gccccgggcg tcccggcggg cctgctgggc
       61 ggcttcccgg atctcgcggc gcagatcccg cgccgaaccg ctgacgtcct cccggatgtc
      121 ggaggcgagc gcggcgaccg actcccggat ctccagttcg aggtcggcca actcgccgcc
      181 gcggtcggcg agttcggccc gtccggcgtc ggtgagcgag tagaccttgc ggccgccctc
      241 ggtcgtgtgg gtcaccaggc cctcggccgc catcttggcc agccgggggt agaccgtgcc
      301 ggcggagggg gcgtagaggc cctggaagcg ttcctccagg aggcggatga tctcgtagcc
      361 gtgccgcggg gcctcgtcca gcagcttgag gaggtagagg cgcaggcggc catgggcgaa
      421 gacggggggc atgctcagag caccttcttc tcggcgggcg ggtcggtggg ggagtccccc
      481 tgcgggccgg gggccgggac gccgccgggg ccgcccggcg ggtcctcgcc ctcgaaggcg
      541 gggcggcgga gcagggccag accgccggag acggtggtga ccttgagggt gccggtgccc
      601 gcgccgagcg cgccggtgat cttcttggcg ccccactggc cggtgacccg cagatcgtcg
      661 aaggcgttgg agaccgtgcc gctcgcggtg ttggcctcca ccgtggcgtc ggccgggtcg
      721 ggcagccgga tggcgacctc cccggagacc gtggtcaggg cgatgtccgc gccctgggcg
      781 gggtccaggt cgaggaccat gtcgccgctg acggagtccg cgcgcaccgc accgcccgcc
      841 ccgtcgatga cggtcagatc ccccgagacg gagtggaacc gcagatcgcc ggtgaccgac
      901 tgcacctcga cattgccgga gacggtgtcg gcctgcaccc tgccggtcag tccgacgagc
      961 gtggcgtcac cggagacccc gcggacgtcc gtacgccccg agatgccgga gaccaccgcg
     1021 ccggccccga ccacgccgac ctccacgcgg gtgccggccg gcaccgtcac cgagatcacc
     1081 gcgctgcggt tccagccctt gcgctccagg aacttcagga agcccttcca ggggaggtcg
     1141 tcgtaggcga ccgagagggt gccgtggtcg cacgagacgg tcagcggcgg gccgtgcagc
     1201 tcgctgatct ccacgcgggc cgggctgccg tccgaggtgc cgacgacgtt cacggtgccg
     1261 ccgaccacgc gcacgctcag ggcgtcgaag gggtcggaga tctccagcgt gcgtggctcg
     1321 gccacctgta ccggtcgctg tgaccactcg ctccgggctg acattcctgg cctcccctga
     1381 tagccgggcg acgcaacata tcgcgtctcg tgggcaacac gatatatcgc ggattgtgga
     1441 agtcaagtgc cggtaccacg caggcgtgat cgccgccgcc gggtgcaacc gcgagccgtg
     1501 gcaggggagt cctggtgagt gaccaccgat gtcatggcgt ctgtcataga ggagttgaac
     1561 tgtgcgtacc tccacggggc tgatctcgac gctggtgctc ggcgccgccc tgagcctgcc
     1621 ggtcaccgcc gcccatgcgg ctcccgccga ggcttcggtc tccgccgccg cggcgtcctg
     1681 ccacgggctg atcacggatg cctactcgct gaacaacaag gccatttcgg cgagccgggc
     1741 aggcagctac aagaaggccg cgaagcgcaa ccacgcgacg gaggggaaga tcgtcaacgc
     1801 cctgggggcg tgccggcacg cgcgccaccg ggcggagatc cggcgcgccc tcgacgctgc
     1861 ccggaacgac atccagggcg ccgagcacca caacaagaag gcctacatcg agcacgaccg
     1921 gcgggccggg cgggcggccc tcaacgacga gtacgacgcg cagcgccgtc tgcgcgacgc
     1981 ggcccactac tcctgatcca ggattccgcc gggacggtcc gtctcccttc cgggagcgga
     2041 ccgtccgccg atgacccggc cgccgggaag cgggggcgcc ggggccccgg ccccggcccg
     2101 ctccccggtg gcttattcgt cctcgtcctc gtcgtccagg cgggccagcc aggtggccag
     2161 ccgctccacc ggtacctcga agtccggatt gagatcgacg aacgtacgca gctggtcggc
     2221 cacccacgcc agggtgacct cctcctcgcc gcgccggttc tccagctcct cgatgccacg
     2281 gtcagtgaaa tacacgcgct ctccaccagg ggtcatgggt cattcccggc caggataggc
     2341 aggctcacgg acctctcgcg ccacagacgc ccgacggcta gcctgatcac ctgtcaacgg
     2401 tcctgcggca attgggaaat tgccgcccac ggggcgcagg aggccgtgat gcaagatcgc
     2461 gcacagcgca tcgaacttcc cgacggtacg gaagtctggg cccgggtctc ccggctggac
     2521 accccggcgc cggacgggac ggacgacgcg gacggggaat tcgaggacgt cggcgcctgg
     2581 gacgcgctcg gggcccgggt cgaggggctc cgcgaggtga tcggcggcgt cgccgccagc
     2641 gtccggcagg ccaccgaacg ggtcgcgccg cacgagacca gtgtgacctt cggcgtggag
     2701 ctgtcggcca agccgggcaa ggccgtcgcc ctgctcgcgg acggcgaggc gaagagcaac
     2761 ctctccgtca ccctcacctg gcggcgtgcg gaccgggagc cgtccgggga cgcgccacac
     2821 gggccgcata ccgccgaccg ccgggagccg gacgattcga gccgctgatg tcgacctccg
     2881 agggccgggc cgccggccgc ggtgaccgcg cccgctacac acagctcctc gaacacgccg
     2941 gacgcaccac cgtcgccctg cgcgccgcac cgggcggggc cgccgcccgc ccctggggca
     3001 gcggggtgct gatcgccccg ggatgggtgc tgacctgcgc ccatgtactc gcggcgagcg
     3061 acgggcggcg ccgcgagacg ggcccggacg gggtcttcgg cgtcaccttc gacggccggg
     3121 tggtgcccgc ccggctcgcc tacgacctga gccggcccga cccggccgcc gggcccgccg
     3181 ccgtccgcgc cgacctcgcc ctggtccagc tgctcgaccc ggcgaccgag cacccctgcg
     3241 cctggctcag cgatcagccg gcgacgctcc tggaggacgc gtacatcttc cgcggccacg
     3301 acgcgtcggg cgcggtgacc gagagggacg gcgacgcggg cacggtccgc cggggggaac
     3361 acgccgtacg tgacgccggt gacggaggcg acccgcggga cgggggcccc gggccgggcg
     3421 acggccccgg cgcccggggg cgcggcgagc acggggcgcc cgccggtccg cgcgcccccg
     3481 caccctccgt cgaccccttc atcgcggtcc gcttcggcgc ccgcgatgcc cggggcctcc
     3541 agttcggcag cgatgtccgg gtctcaccgg gggcctccgg cgggccgctg ctcgactgtg
     3601 accgcggcga ggtggtcggc atcgtcaagg gccgccacca acaggaccat gtcgggctgg
     3661 cggtgccggt cacggcgctg cgcgggctgg ggccggaaca cctggtcgcg ggcgccgagg
     3721 gcctggggcc cgacccgtac cacgcgctga tgagcctgca cgaccgctgg cactgggccg
     3781 gtcaggatct cggccgggcc gtcgggccca cctggttcga cgcccagcac acgatcatgg
     3841 cgggccgcgg ccgcctgtgg ggcgtccagg aacggctcca ggcgctggac ctgctcgccc
     3901 ggctgcccgc accgcgcgat ccgctggtcg tggaggccgc ggtcggcgag gtactggagc
     3961 gcggcgagcg gcccggagcc tggctgctgc gtacctggcg ggacgggcac ggcgccctct
     4021 accagggcag cgacccgtac acggagctgc gcgcctttgt gcactatctg cggatcgtgg
     4081 cgcagctgac cgccgacgag gtgcgcgacg ccccgggcga ggaggccgcc gcggtccgcg
     4141 aacaggccac caggctcgcg gagttcgtgc aggccaaagc ggtggtgctg cagccgcagg
     4201 accgccggag gatagggccg gtacgccgcc ggccgtgctc cgtgctcgtc gagttcgagc
     4261 cgctcttcta cgacgagggc gggcaggagc tgttcaactg gtcggtcagc gagggctacg
     4321 gccaggggca gtggctgcgg gtggatgtcc aggagtcggc cggcggggtg ccgttcgagc
     4381 aggcgcggga gcaggtgctg cggcggctcg gcgggcggct gctgcgggcc gacggcgatg
     4441 ccgggccgaa tgcccgggtg cgcctggagg tcgccgtccc cgaaggccac tgggacaccg
     4501 ccgccggcca atgggaggtg gcggcctcga cccggcgcac cgcccggctg cggccggtgg
     4561 gccccgggcg cgcggtgatc ctgcgcgacc aggggcggcg cgagcaggtc gacccggcct
     4621 ggctgcgccg ctggcagggc ctggccgccg cccgtgagct acaggccctg cgcatcccgc
     4681 cgcggccggg cgccgacggc cggtcccctt ccgccgaggc gatctggcgg ctgctggaga
     4741 cggccggcga gggcgcgctg ccggcgctgt gccacgccgt cgccgacggg ttcggccggg
     4801 acgcggtcgg cgtcgccctg gacaccggct tcccggccgg gctgtggccg gcccacgggc
     4861 acggcgagga acgggactgc gacgccggct gcgaggagtt ccaccgcggg gtgcgggagc
     4921 tgctccaggg gtcgggcggg gtggcccggc tgcccgagct ggtccggcag ttgcgggcga
     4981 aggccgcgga ggccgcggag gagggcacgc actgggcgcg cgatctggtg ctcctgtacg
     5041 acgacccgga ggacccgatt ccgccgctct tcacggaccg cccgcagatg tcgccgcgat
     5101 gagcggtacg gggcgccgcc ccctggcgct ccgggcgccg cgtacgcccc gtacacctcg
     5161 cacgcgcccg gtgcccggcc gggcggcatc cgcccctccc gcggcaagtc acgccccgta
     5221 cctggcactt gagcgcccgc gatgcccgtg cgggagaccg gaaaccgccc cgtgtgcttc
     5281 cgtccgggtg ggtactgtca tagcgtcgtg gaagacttgt tcgtgaggac gcgactgcgt
     5341 gactgtgggt ggcggacgcg gggggaggcc gagcggatgc cgatgtctcc ggcggtccgc
     5401 catgaccatc gctcctgacc gaggcctggc cggcgacgag gagttccgac gtgagcgact
     5461 ggctcatcta ccgtggcgcg ggggcaccgc acgacggaat tgagcatctt ccgccgccac
     5521 ccccctggcg cgatttcgac ggcggccccc tcgtggcgcc gccggccgcc ctcgacccct
     5581 cctccgagcg caggctcggc gtgcagcacc gggaggccag ccaccaccgc cccggcgaga
     5641 ccgagcgcga gctggtcaac gccgccctct atctgcgccg cccgctgctg gtgaccggcg
     5701 caccgggcag cggcaagagc accctggccc attcggtggc ctacgaactc ggcctcggcc
     5761 gggtgctcgg ctggccggtc gtcagccgca gcaccctccg tgacggcctg tacgactacg
     5821 acgccatcgg ccgcctccag gatctccaga tcgcccgcgc cgccccggcc accgcggagg
     5881 gtgcggcggc ggccggcccg gaccccaccg acgaacccgg cggcggtatc ggccgctata
     5941 tccgcctcgg cccgctgggc acggccctgt tgccggccgc ccggccccgg gtgctgctcg
     6001 tcgacgagct cgacaagagc gatatcgatc tgcccaatga cctcctcaat gtgctggagg
     6061 aaggggagtt ccggattccg gagctggagc ggctggccgg atccgccccc gaggtggagg
     6121 tgctcagcga cgacggcaca cgggtgacgg tgcgcgacgg ccgggtgcgc tgccgtgcct
     6181 tccccttcat cgtcctcacc agcaacggcg aacgggactt cccggcgccc ctgttgcgcc
     6241 gctgcatcca cctccatatc ccggtgcccg acaaggagcg gctcgccgcc atggtgcggg
     6301 cgcacttcgg cgagggggcg gcggagcgct acgaagcggt gatcgaccgc ttcctggacc
     6361 gcgagcccgg cgatgtccgc gccgtcgatc agctcttcaa cgccatccac ctgacccaga
     6421 gagcgggctg gacggacgag gacgaggagg agacgcggcg gcgtctgacg gcggagctga
     6481 tgcggcctct tgaccggacg aggtgagtcc ggtgccccct ggggagcccg gcccgggccc
     6541 cctcgacgaa ctcgtcgccc ggctgaccgc ggcggggctg ccggccgacg cccgcgggat
     6601 ggccgatgcc ctctggctcg cccagtggat caccccgggc ccctcgcggg ccgagggcac
     6661 cacggacgcc gggcccaccc acggggaccc tccggaccgt acggattcag ccactttccg
     6721 ggtggggccc gccgtatctg ctgagttctc ggggacaggt gggaccgcag cggccggcag
     6781 cgggagcgaa acggcggacg gggaccccgc gccggccgtg ctccagcagg gcgcccggcg
     6841 ccgggtcgcg gagctgctgc ccacccgtga cccgggcgag acgcccgcgc ggttccccga
     6901 cccggaccgg cagcgtctcg gcgaggtcgc ggtcccgatc gcctccgcgt tccccggact
     6961 gctgccgctc cagcgcgcgc tgcggcccat ccagcgctac cgcccgccgg tcgccccggt
     7021 cccccggagg ctggacgagc ccgccaccgc cgagctctcc gcccacgccg aaatgatcat
     7081 cccggtgctg cgcggggtgc accgccgggc ggccggtctg cggctcctga tggacggctc
     7141 gtcctcgatg gccgtctggg aacagatgct gcacgacctg cgccaggtct gtgagcgggt
     7201 cggcgccttc cgcgacgtca cggtgcacta cctccatccg cacggcccgg acgtgggcgt
     7261 cgcggcggcc cccggccccg gccgtccgct gcgccccgcc gaccagctgc acgacccgac
     7321 gggccatcac ctcaccctcg tcgtcagcga ctgcgcgggc cccctctggc gggacggccg
     7381 gatgcagcgg ctgctctacc gctgggcggc cgacgccccg ctcgccgtcg tccagccgct
     7441 gccgcagcgg atgtgggcgc gcaccctgct ccccgccgtc gccggcaccc tcgtccgccg
     7501 ccagggcccc taccaggcgc tcggcttccg cccggcccgg cgccgccgcc gtcccgccgg
     7561 gcctccgggc accgccgaag cgccccgtga gcgcgccatt ccggtcctgt ccgccactcc
     7621 ctccgccctc ggctcctggg cccggctggc cgccgccgac gccggtctct cgctgcgcgg
     7681 tgcggcctcc gtcgtccggg ccgaccacgg caccgaactc ccggccggac cgccgcctgc
     7741 gcccgggccc gccgcgccgg cccgtatggt ccgcgagttc gaccagcagg cctcaccggc
     7801 cgcccggctg ctcgccgtcc atctgtcggc cgtgccgctc gcgctgcccg tcatccagct
     7861 cgtccagcgc gcgatgctgc cgcagaccgg cccggccgag ctggccgagg tgctgctcag
     7921 cggactggtc acgcaactcc cgccggacga gcggccgtcg ggcgagcagg ccggggtgag
     7981 cggcccctgg tacgacttcg cgcccggtgt acgcgatgaa ctcctcgccc ggctcagtgc
     8041 gggggaggcg gccctggtgc tcaagcactg ctcgctctac gtcgagcgca ccttcggccg
     8101 cagcgcccgc aacttcccgg ccgtcgcggt cgccatgctc tccggcagcg gccgggagcc
     8161 cgagaccggc cagcgggccg tccccgaacc cttcgcccgg gtctcggaac gggtgctgcg
     8221 ccgcttcgaa cccgcgctgc gcccgcccgc ccgccggccg tacgcgaccg acggacccgc
     8281 cgcggaaggc gcggccctcc tggagcgcta cgaacaggac cgcgccggcc gggacctgat
     8341 cgaggcggtc cggctgctgc gcgccgccac cgaacgcctg ccggtggccg gcaccgacct
     8401 cgcccgcgcg ctgctgcacg cctgggcgac ctggcgccag ccggacgccc tggaggaggc
     8461 ggagcacgcg gcccgcgccg ccgaacgggc cacggcgggc gagcccgtcg acgaccagga
     8521 gggcgcggcg gcgggccggg aggccgagcg cacccgggca ctgatcgtgc tcggccgggt
     8581 cggccacgcc cgcgcccggg aacgccgcgc ggccggcacc cccgccgagg agcgcaccgc
     8641 gctcgccgac gccgcccgcc atctgcacgc cgcctgcggg ctgatgagcc tgctggaccc
     8701 ccgcgttctg gagagcatgg tgttacgcac cgaggtcctg cgccgcctgg ccgccctgcc
     8761 gcccgtaccg agcaccgacg gggcgaccga ccccgacccc ctcgacgagg cggaacgctc
     8821 gctcaccacg ctcctcgacc agtggcccag tggggagcag gtgccgggcg aggtctatgc
     8881 cgcccgtggc ggtgtgctgc tcgaccaggc ccggcgggcc gcccacggcg acaccgaagg
     8941 gccgcgcccc gccgaggcgc tcgccgtccg cgccgccgac gacctcgaca ccgccgcggt
     9001 cctgctgcgc cgccgcggtg gcgcggccga ccggctggtc tgcgagaccc tgctcgacct
     9061 cgcggcggcc cgccagctca acggcggcgc ggctctgccg tccgtgctgc ccaccctcga
     9121 acacgcccgt gcgctggccc atgaactgga cgaccgggca ctggaagcgg acagcctgcg
     9181 ccgtacggcc gccgcccagc gcgccgtgca cacccgtacc ggcgatctca ccgcgctgga
     9241 cgccgccatc gccgcgctgg ccgccgccct ccggctgacc acccccgatt cgcccgagca
     9301 cagcgcgctg ctcgccgagc gcggtgcggc actgctgctg cgcgcccggc tggagccggc
     9361 cggggagccg ggcaagcggc tggccaacga ggcggtacac gtcctgcgcg aggcgctggg
     9421 gcgggtcgcg ccgcaggacc ccgacctggg cagtcaccgg ctgctgttcg gccgcgccct
     9481 gcggctgcgc tacgaacgcc agccctcgct cgccgatctg cacgaggccg actggatcct
     9541 ggagctggcc gcccggggcg cggacgtacc ggacgcggtg gcggccgagg catggctcga
     9601 agtgggcgat gtgcagctgc tgctggaccg ccgcttcgac tcccgtgagc gccatgaccg
     9661 ggccgccgcc tgctaccgcc gggccgccgc ggccgcccgg cgggccgaca gcgccctgcc
     9721 ggccgcccgc gcccaccacc gccgcggcga ggtcctggag gtcaccgccg gaccccggtc
     9781 cgcgctgcac gcctaccgtg agagctggga gcagtggcag cgggccggcg aggacaccgg
     9841 ccccgaggcc cagcgcaccc gtgcccgtat gcgcgccctc gaatccaccg cctgaccgcc
     9901 ccgagcaccc cgtccggctg cctggccgtc cgcagcggaa cgtgtttctg tggacggcag
     9961 ttcgggaaca cacccgtcca gccggccaga ggagagcagc gtggcgacta ccccccgcac
    10021 cgaaccggct gtggccgccc cgccggggcc gtcggccgag cggctgccgg actttgccgg
    10081 ggtcgacgtg ggcgttctgg cggcacggac cgaccatgcg gtgctgggcg aggtggcggc
    10141 gctgctgctg cgcaactggc cgtcggcgga ggacgccgtc gcctactacg aggacggtcc
    10201 ggagaaggtc ttgcactgag ggtcgagaac ggttgttttt gggcaaacgt gcaaggaaac
    10261 cggccagttg ctgggggaat tcggttcttc gcccgaaggc ggagccatgt accaggcagc
    10321 gggccggaat cggcgagccc gtacctcgac gcaggcagac gagagcaggg ggcgacccgt
    10381 ggcgggggag aagaccggcc cgaccgctgt cgtgcccttc cggcagttcg tgctcaaggt
    10441 ccacagccgc tgcaacctcg cctgcaccta ctgctacatc tacgccgggc cggaccgcag
    10501 ctggcgcgcg cgcccgccgg ccgtcccggc cgccaccatg cgccagaccg ccctgcgaat
    10561 cgccgaacac gcccgcactc accggctgcg cgaggtccgg atcgatctgc acggcggcga
    10621 gccgctgctc accggccccg gaccactgct ggcccaggcc gccgcggtcc gtgccgcgct
    10681 gcccgccggc tgtaccgccg aattcggggt gcagaccaac gggacgctgc tcacccggga
    10741 catgatcgac accctcggcg ccgcagggtt ccggctcggc ctcagcctcg acggcggcac
    10801 ccccggcctc aaccgccgcc gtatcgacca cgccgggcgg ccctcctggc ccgcggtctc
    10861 ccgcgccgta cgcctgctcc acgaccggcc cgatgtcttc gccggcatcc tgtgcaccat
    10921 cgacgtcacc gccgcccccg ccgaggtcta cgactcactg cgcgccctgg accccccgat
    10981 ggtcgacttc ctcctcccgc acgccaactg gaccagcccg ccgcccgccc ccctcggccc
    11041 ggccggccgc accccgtacg gcgactggct gtgcaccgtc ttcgacctgt ggtgggacgg
    11101 cggccccggc ccccgcgtac gggtcttcac cgaaatcctc ggcctcctcc tgggccgccc
    11161 cagctccagc gaggcggtcg gcctctcccc ggtcgtcgcc ctggtcgtcg acaccgacgg
    11221 cgccatcgaa caggtcgact cgctcaaatc cacctacgag ggcgccgccg ccaccggcct
    11281 cgacgtcttc cgccacacct tcgacgacgc cctggcacac cccggtatgg ccgcccgccg
    11341 gagcggccgg gacggcctcg gcgcacagtg ccgcggctgc gccctggtgg aggtgtgcgg
    11401 cggcggcaac tacgcccacc gctatcgcgc ggacgccggc ggcttcacca acccgtccgt
    11461 ctactgcgcc gacctggagc gcctgatccg gcacatcgcg gcccgcctgg acgccacggt
    11521 cgccctcaac tgacctgcgt ccgagatgac ctgacgcact gtcgtcatat ggagggacac
    11581 ttgggctatc gtgccaaaaa gccagggcgt gcctgatgag acagcctctc cgcgcgcgca
    11641 ccaccgcatc ccagggagac ggtcgcatgg tcgatcaggc ccatttttcc ggtcccaccg
    11701 gctccaacga acacatcacc atcagctacg cgggcttcac ccggccctgg gccgcctgga
    11761 tctcccatca gctggagcag cagggccacg gcacgaccat gctgcgctgg gacccccagg
    11821 tggacaccgc gctggtggag gagctgtcgg ggctgctgga ggccgagggc cggctgctga
    11881 tggtgctgga cgactggtat ttccggctgg gccccaagac gcaggacgag tggacggccg
    11941 cgctgcgcga ggtggtctcc gcgcacgccg accggttcgc cgcggtgagc gtggccaccc
    12001 agagcctgcc cgccacggcc tccctgctgc gccccgtcga cctgcgtgac ctggacgccc
    12061 acgaggccaa ccgccgggta ctgcaacggc tcggcatcgc ggcgccgggc cgggccgtgg
    12121 acgaggacgc gcccggcgcg ccccgcttcc cgaacaaccc gcccgaggtg tggaacatcc
    12181 cgcgccgcaa caaccgcttc accggccgcg accacgtcct cgaagcgctg cacggcaagc
    12241 tggccggctc cggcgcgggc gcgggcccgc cgctggagac ccggctcgcg ctgtacggca
    12301 cctccggcgt cggcaagagc cagatcgccg ccgaatacgc ccaccgcttc ggcaacgact
    12361 acgacgtggt gtggtggatc agcgccacca accgcggcgc cgcccgtgag cagctcgccg
    12421 aactcgccac ccggctcggc ctgcccgtgg gccgcgagct gggcgaccgc atccgcgccg
    12481 tccacgaagc gctgcgcgtc ggccgcccct accgccgctg gctgctgatc ttcgacagcg
    12541 ccgacgacat ggagtcgatc gaggacctgg tccccgacgg ccgtggccat gtcctgatca
    12601 ccaccctgac ccgcgactgg tcgggctccg gcagcgcaca ggagatcgag gtgccgccct
    12661 ttgagcgcgt cgagagcgtc gcctacgcgc ggcggcgtgc cccacggctg acgccgatgg
    12721 aggccgatct gctctccgag gcggtccagg acctgccgct gctgctcgcc cagaccgccg
    12781 cctggctcga cgccaacccg atggccccca aggagtacat cgagctgatc cgccgcggcg
    12841 agcccagcct cgtcggcatc cggatctcct ccgactaccc catggccttc cagacgagct
    12901 gggccataac tctcaacacg ctgcgcgaac gcagcccggc cgcggtcgaa ctcctcaagc
    12961 tgttcgcgtt cttcgccccg gacaccatcc ccgtgccgat gctcgcccgg gcccgccgcg
    13021 gtgacctgcc cgagcacctc gccgacctgg ccgccgagcc gatcagctgg aacaccgcgc
    13081 tgcgccggct gaccgagtcc accgccgtac gcctcgacta ccaggtctcc caggacgccg
    13141 acccggccgt ggagaccgcg ctgatgcacc ggctctacca ccggttcctg cgcagcgaca
    13201 tgaccgagga cgagcgcgac ctgatgtcgg cgtgcgcctg ccgggtgctg gtcaccgccg
    13261 acccgcagaa ccccgccgac acccgctact gggagcgcta cgccgaactc atcccgcatc
    13321 tggagccggc cggcgtcctc gacagccccg agcccgcggt ccagcagctg ctgctgaact
    13381 gcgtggaata tctgcgggtc cgcggcgaat accgcatggg cctgcggctg tgcgaacagt
    13441 tcatgtcccg ctggcgcacc cgcctcgcgg ccacccagcg caccatgctc gtcctcaccc
    13501 accagcacgc caacatgctg cgccggctcg gccgctaccg cgaggccgag gcggtcggca
    13561 gcgccgtcgt cgaccagctc gccgccgaac gggacccctc cgacgccgat ctgctgcggg
    13621 cccaggacgg gctggccggc acgctgatcg cgctgggctc ctacgagcag gcctacgacc
    13681 tcttcgacgc cgtctggcgg gcctacaccg agctgctcgg cccggaggca ccccgcaccc
    13741 tctcctcgcg gcacaacctc ggcagtgtcc tggcgctgct cggccggtac gaggaggcgc
    13801 tggtcaccca tcgcgaggtg ctgtccttcc gggagcgcga gctgcgcgcc cgccaccacc
    13861 tcacgctcaa cgcgggcacc gcctacgccc gcaccctgcg cctgctcggc cgttaccgcg
    13921 acgccacctc cagccaggag ctcaacgccc ggctgcacct ccaggtgatg ggcgcgcaca
    13981 ccccgcagac cctgcgcgcc gagcacaatc tcgcgctgtg cctgcgccgc tccggcgagg
    14041 tcacccgggc cgccaccctg ctggccgatc tcgtcgagcg ctcccgccgg gtgctcgggc
    14101 cccgccaccc cgagacgctg atggtgcgcg cggaccatgc caccttcctg cgggagcacg
    14161 gcgatctcgg gcacgcccgc gacctcgcgg aggaggtcgc cgagcgttac cgggccctgg
    14221 ccggcgagcg ccatccgtac accgtcggca ccctggggaa cgtcgggctg gtccgggggg
    14281 agttcgggga cccggccgac gcgctggacc tcgccgaacg cgcgctgagc gggatggccg
    14341 aggccatggg gcccggccac ccctggacgc tgggctgtgc gctgaacgcc gccgcggccc
    14401 gcaaccgggt ggacgacgag gagggcgcgg tggagctggg ccgcgacacc ctggagcggg
    14461 ccaaggcgag gctgggggac acccatccgc tgaccctctc cgcgaagacc gcgctgtccg
    14521 aggacctgcg ggcgctccgc cgcggccagg aggcggcgaa gctcgaacag gaggcgatcc
    14581 agcagctctc cgagaccctg ggcgccgagc atccgcacac cctgtccgcc cggcgccgcc
    14641 gccgcccgta ctgggacttc gaaccgcagc ccgtctagga cctgacgagg ggacttcgcc
    14701 ccacgcatgc ggaagggccc gcccccaccg gggacgggcc cttccgctgg tgcctgccgg
    14761 ttctccggcg gcccggacgc ttacgcgtcg aaggcctccg cgaccagctg cgcctgctct
    14821 gcctggtgac gcttggcgga gccgacggcc ggcgacgagg agtgcggccg ggagatccgg
    14881 cgcagccgct cgccgtgcgg gacatcggcg ccgacggcca ggtcgaggtg gtcgatcagg
    14941 ttgaggccga ggaacggcca ggcaccctgg ttcgccggtt cttcctgggt ccacaggtac
    15001 ttctcggcgt tcgggaactt ggcgatctcc gcctggagct ccttgccggg aagcgggtag
    15061 agccgctcga tacggacgat cgcggtgtcg tttgcaccgc gcttctcccg ctcggcctcc
    15121 aggtcgtagt agaccttgcc ggagcagaag atgaccttgc ggacatcctc gggcttgacc
    15181 gtggagtcgc cgatgacggg gcggaagccg cccgacgtga actcatccgt ccgcgacgcc
    15241 gcggccttca gacgcagcat cgacttcggg gtgaagacga ccagcggctt gtggtgcggg
    15301 ttgtggacct gccagcgcag caggtggaag tagttcgacg gcagggtcgg catggcgacc
    15361 gtcatgttgt tctgcgcgca cagctggagg aaccgctcga tacgggccga ggagtggtcc
    15421 gggccctggc cctcgtagcc gtgcgggagc agcagggtga cgccggacgt ctggccccac
    15481 ttctgctccg ccgaggagat gaactcgtcg acgaccgtct gggcgccgtt gacgaagtca
    15541 ccgaactgcg cctcccacat gaccagcgcc tccgggcggg ccagggagta gccgtactcg
    15601 aagcccatcg ccgcgtactc gctgagcagc gagtcgtaga cgttgaagcg ggcctggtcc
    15661 tcggagaggt agagcagcgg cgtgtagtcg tcgccggtct cccggtcgat gagcaccgcg
    15721 tgccgctggc cgaaggtgcc acggcgggag tcctggccgg cgagccggac cggggtgccc
    15781 tccatcagca gcgagccgac ggccagggtc tcgcccatgc cccagtcgat ggcgttgtcc
    15841 tcgacctggg ccgcgcggcg ctggagctgc ggcatcagac gcgggtggac ggtgacccgc
    15901 tcggggatgt tgacctggga ctcggcgatc cgcttgacga cctcctggga gatcgcggtg
    15961 tccacgtaga ccgggaactc ggccttgggc tgcggcacct cgggggccac cggggccgtc
    16021 gtggcgtcgc ggacctcggt gaagaccttc tccagctggc cctggaagtc ctggagcgcc
    16081 tgctcggcct cttccagcgt gatgtcgcca cgaccgatga gggactcggt gtagagcttg
    16141 cgcaccgagc gcttcttgtc gatcaggtcg tacatcagcg gctgggtgaa ggccgggttg
    16201 tccgactcgt tgtgaccgcg gcggcggtag cagatcaggt cgatgacgac gtccttgttg
    16261 aacgcctggc ggaactcgaa ggccagacgg gcaacgcgga cgacggcctc ggggtcgtcg
    16321 ccgttgacgt ggaagatcgg cgcctcgatc atgcgggcca cgtcggtggc gtacatggac
    16381 gaacgcgacg actccggggc ggcggtgaag ccgacctggt tgttgatgac cacgtgcacc
    16441 gtgccgccgg tgcggtagcc gcgcagctgc gacatgttca gcgtctcggc gaccacgccc
    16501 tggccggcga acgccgcgtc accgtgcagc tggatcggca ggaccgtgaa gtccgtgccg
    16561 cccttgttga tgatgtcctg cttggcgcgc gcgacaccct cgacgaccgg gtcaacggcc
    16621 tccaggtggg aggggttggc ggtcagcgag accttgatct gctcgccgtc cagaccggtg
    16681 aaggtgccct cggcgcccag gtggtacttc acgtcgccgg agccgtgcat cgacttcggg
    16741 tcgaggttgc cctcgaactc gcggaagatc tgcgcgtacg acttgccgac gatgttcgcc
    16801 aggacgttga ggcggccgcg gtgggccatg ccgatgacga cctcgtcgag gcgcgactcg
    16861 gccgcggagt cgatgaccgc gtccagcagc gggatgacgg actcgccgcc ctccagcgag
    16921 aagcgcttct ggccgacgta cttcgtctgg aggaacgtct cgaaggcctc ggcggagttc
    16981 agccggcgca ggatgcgcag ctgctcctcg cgctcgggcg acttgtgcga gcgctcgacc
    17041 cggtcctgga tccacttgcg ctgcttgggg tcctggatgt gcatgaactc gatgccggtg
    17101 gtgcggcagt acgagtcacg cagcacgccc aggatgtcgc gcagcttcat catggacttg
    17161 ccggagaagc cgccgaccgc gaactcgcgc tccaggtccc acagggtgag cccgtgctcg
    17221 gtgatgtcga ggtcggggtg cttgcgctgg tggtactcca gcgggtcggt gtcggccatg
    17281 acgtggccgc ggacccggta ggagtggatc agctcgaaga cccgggcggc cttggtgacg
    17341 tcgtcgtcgt gcgaggcgtc gatgtccttg agccagcgga ccggctcgta ggggatccgc
    17401 agcgacttga agatgtcgtc gaagaactcg ttctcgccga gcagcagctg gctcatgatc
    17461 cgcaggaact cgccggaggc ggcgccctgg atcacccggt ggtcataggt gctggtcagc
    17521 gtcatgacct tggagacacc cagcttgttc agggcgtcct gggaggtgcc ctggaactcc
    17581 gcggggtagt ccatcgcgcc gacgcccatg atcatggact ggccgggcat caggcggggc
    17641 acggagtgca cggtgccgat gccgcccggg ttcgtcagcg acgcggtgac tccggtgaag
    17701 tcgtccatcg tcagcttgtt gtcgcgggcc cggcggacga tgtcctcgta ggcctgccag
    17761 aactcgaaga aggtcagcgt ctcggccttc ttgatggcgg cgacgacgag ctggcggtca
    17821 ccgttcggct tcaccaggtc gatggcgaga ccgaggttca cgtgctcggg cttgaccagc
    17881 gtcggcttgc cgttcttctc cgcgaaggag tggttcatcg acggcatggc cttgagggcc
    17941 tgcaccatcg cgtacccgat gaggtgggtg aaggagacct tcccaccgcg ggcgcgcttg
    18001 aggtggttgt tgatcacgat gcggttgtcg aagagcagct tcaccgggac cgcgcggacg
    18061 gacgtggccg tcggcagctc cagggaggcg ttcatgttct tcgcaacggc ggccgagggg
    18121 ccgcgcaggg tgatgaactc gggaccggcc ggagccgagc cctcctcggc ggccggcttc
    18181 gcggcgggct cggccggagc ggccttcgcg ggctcggcct tcgccggagc ggccttcgcc
    18241 ggagcggcct tcgccggtgc cggagcgctc gcggcgggct tcgccggggt ggccggcgcg
    18301 gcggcggccg gcttcggctc ggctgcgggc gcggccgact gcgccggggc ggccggagcg
    18361 ggggcagcac cctccgccgc ctggcccggc gcggtggcac cgcccggctt gtagtcagcg
    18421 aagaagtccc accaggctcg gtctaccgag ttcgggtcct ggaggtactg ctggtagatc
    18481 tcgtcgacga gccactcatt gggaccgaac gcagcagcag ggttcttacc ctgcccctct
    18541 tggtcggtcg agatgctcga gctgttgggg gactgtagcg acacggcggc aaccgccctc
    18601 ttccgcttcc taaggtggtg gacagcggga ataaaggcta cgcctgttgt gacccttggt
    18661 gcaggccggg aggggcactc gtcgtgtacg tcacattccc ggccgggttt cggggcatga
    18721 cttggcggga aacacacgaa gtttgcctct gtgcgggtag gagtgatcac caccacaccc
    18781 gcgggggagt gcttccacca ccgaccctac gtcagcggcc gtcagcttcg agctgactcc
    18841 agccccggaa gagtgacgcg gatccggcaa ccgcgggacg attccgcgac gccgatgcgt
    18901 ccgccgtgca gatccaccgc ccagcgggcg atcgccaggc ccaggcccgt accgccgtcg
    18961 ctgccggggc ccgagggggc cgggccgccg cggttgaacc gctcgaagac ccggtagcgc
    19021 tccgcctcgg ggatgccggg gccctcgtcc tgcacctcca gcaccaggct ctgcggcccc
    19081 tcgccccgcc gtgcgtgcac ggtgacccgg ccgtgccggg ggctgtgctt gatcgcgttg
    19141 tcgatgagat tggccacgac ctggtgcagc cgctcggcgt ccgcgtgcgc ggtcagctcc
    19201 ggcggcgaga cgtcgaggtg cagatggacg tccgtacggg tgtgggtgcc ggagccggcc
    19261 accccggcca gcgtggcggc gccccggctc atgttggcct ccttgagcac cccggacaga
    19321 tacggccaga cctcgaagcg gcgggcgtgc agcggcacca ccccgttgtc cagccgggac
    19381 aggtccaaga ggtgctcgac cagccggccc agccgctcgg tctgcttcag cgccgtacgc
    19441 atcgtctccg ggtccggctc gcagacgccg tcgacgacgt tctccaggac ggcccggagc
    19501 gcggcgatgg gggtgcgcag ctcgtgcgag acattggcga ccagctcctt gcggtgggtg
    19561 tccaccgctt ccagatcggc cgccatccgg ttgaaggcgt tcgccaggtc gccgaactcg
    19621 tcgcggcgct ccgagcggac ccggcggctg tagttaccgt gcgccatcga ccgggtgaca
    19681 tccgtcatct cgtcgagcgg ggcggtcagg ctgttggcca cgaactgggt gatcagcagc
    19741 gaggcgatga tcgagaagat cgtgatcacc cgcagctcgg tcgccgagtg catcgcgacg
    19801 aacaccagca gggtggtgat gatcaccgag acgctgacca gcgccccgag tgcggccttg
    19861 acggagcggt acgggtccag cgggcgcagc ccctcccaga cgcgctgcca cagctcggtc
    19921 agacgggtgc gtggcgaccg cgtcatgcgg ccggggtctc cagggcgtag ccgacgccgt
    19981 ggacggtgcg gatccgctcg gcgccgatct tgcggcgcag cgccttgatg tggctgtcga
    20041 ccgtacgggt gccggaggcg tcggcccagt cccacacctc ggccagcagc tgctcacggg
    20101 agagcaccgc gcgcggggtg ttcgccaggc agaccagcag atcgaactcg gtgggcgtca
    20161 gatggacgtc cgcgccgcgc acccgcaccc ggcgctgggc gtggtcgatc tccagctcgc
    20221 ccagccggag gatgccgctg cgcggggtgt gcgcggccag tgcggcgcgc tcgacccggc
    20281 gcagcagcac gtgcacccgg gcggccagct cccgcatcga gaacggcttg gtcatgtagt
    20341 cgtcggcgcc gacgccgagg cccaccagca tgtcggtctc gtcgtcccgg gcggtgagca
    20401 tcatcaccgg caccggacgc tgggcctgga cccggcggca cacctccagg ccgtcgaagc
    20461 ccggcagcat cacatcgagg accagcagat cgggctgcca ggcctcggcg gtgtccacgg
    20521 cggccgggcc gtcggtggcc gtctgcacct ggaagccctc ggcgcgcagc cgggccgcga
    20581 tggcctcgac gatcgtgggg tcgtcctcca cgaccagcac ccggcgctgg gcacccggcg
    20641 tggccgcggc ggcgccgccc tgcgttgtct gagtctggtc catcgcccgc ccctgcatgt
    20701 ccctgcgtgg tcgcgtcttg ctgggcagca gcgtacgggc atggtgtgac tgtcggctac
    20761 gcgcccttcc gcgcgagatg gaccacgtcc gggacgcctc ggacaacggg gatctcttcc
    20821 gtatgtaccc cgctgaaacc ggcatttcgc agtgcttcct cgaaggccgg tgagggctgc
    20881 gcggaccaga cggcgagcac tccgccgggg gtcagacggt cgcggcaggc ggcgagtccg
    20941 tcgggggagt agaggctgtc gttgtcctcg gtgacggtcc agtcggggcc gttgtcgatg
    21001 tccaggcaca gggcgtcgta ggtgtcccgg accgcctccg tgcgcaggtg ggcgaccagg
    21061 tcggtgtgca ggatcccggt gcgtggatcg gccagcgcgt ccgccgagac ggccgacagc
    21121 gggccggtgc ggtgccagtc gatgaccgcc tcctcgcgct cgacgacgac gatccggccc
    21181 cagcgcggct gccgggcggc gcgggccagg gagaagccga caccgaggcc gccgatcagg
    21241 acggaggggt gggcgcggcc ggccggcagc gcgtccagcg cggcgtcgat cagcagccgc
    21301 tcggaccggc cgtcggaggt gtccatcagg aagcagccgt tggcgatgat ctcgtagatc
    21361 accggtgccg cgggggtgcc ggggccgtcg gtgccgggcc cgccccgctg ccgcagtacc
    21421 acctcgccgt acgggccctc gcggcggtcg agcgtgcgcg gggcctcggg ggcgccggtc
    21481 cttgcctgcg tcggtgtcac gggagccatg gcgccatggt ggccaatacg ggg
//
