LOCUS       NZ_BBNO01000001        21292 bp    DNA     linear   CON 19-AUG-2024
DEFINITION  Streptomyces lydicamycinicus strain TP-A0598, whole genome shotgun
            sequence.
ACCESSION   NZ_BBNO01000001
VERSION     NZ_BBNO01000001.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces lydicamycinicus
  ORGANISM  Streptomyces lydicamycinicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Komaki,H., Hosoyama,A., Igarashi,Y. and Tamura,T.
  TITLE     Streptomyces lydicamycinicus sp. nov. and Its Secondary Metabolite
            Biosynthetic Gene Clusters for Polyketide and Nonribosomal Peptide
            Compounds
  JOURNAL   Microorganisms 8 (3), 370 (2020)
   PUBMED   32155704
  REMARK    DOI:10.3390/microorganisms8030370 Publication Status: Online-Only
REFERENCE   2
  AUTHORS   Komaki,H., Ichikawa,N., Hosoyama,A., Fujita,N. and Igarashi,Y.
  TITLE     Draft genome sequence of marine-derived Streptomyces sp. TP-A0598, a
            producer of anti-MRSA antibiotic lydicamycins
  JOURNAL   Stand Genomic Sci 10, 58 (2015)
   PUBMED   26380643
  REMARK    DOI:10.1186/s40793-015-0046-5 Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1269470)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: Newbler v. 2.6
            Genome Coverage                   :: 93x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000829715.2-RS_2024_08_19
            Annotation Date                   :: 08/19/2024 02:08:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,323
            CDSs (total)                      :: 7,237
            Genes (coding)                    :: 7,092
            CDSs (with protein)               :: 7,092
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 6 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 54 of 145
            Pseudo Genes (incomplete)         :: 123 of 145
            Pseudo Genes (internal stop)      :: 9 of 145
            Pseudo Genes (multiple problems)  :: 39 of 145
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:07:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 366761
            Orig. end                         :: 388053
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBNO01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21292
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="atropopeptide"
                     /region_number="1"
                     /rules="atropopeptide_p450"
                     /tool="antismash"
     cand_cluster    1..21292
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="atropopeptide_p450"
                     /kind="single"
                     /product="atropopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21292
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11292](-)"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11292)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
     gene            847..2055
                     /locus_tag="TU31_RS01595"
                     /old_locus_tag="TPA0598_01_03480"
     CDS             847..2055
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177249.1"
                     /locus_tag="TU31_RS01595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03480"
                     /product="hypothetical protein"
                     /protein_id="WP_245698373.1"
                     /transl_table=11
                     /translation="MTSPEGTRAVPGTPGAEVPPPETTDTPARRLRGVPRQRHRTARSG
                     EPRAAARDTGTLAFVESPVQLLNVLEWAHTAQATGLTVVVLSPQDPMTRGQLRRMAELA
                     RDEGHTVRWEEARGGPTAPMRTIGGLTPLLRRAHRVVIGDPFSRYVQLLLSLARARDLV
                     VVDDGTATMEFISQLARGEQLVRWHRNGSGRGPRDLIFAPFSATARRRLTPAPEGGRRT
                     VGLFSSMPVEAPPGVEVTTNEFAWTRSRFGPPRLTRAADIVGTSLVETGVVDAERYLAA
                     VAGLARTHGATRYFAHRKESTEKLRRLVGETGLEIVRPDLPLELIARRGPIGRLIVSFP
                     STVVHTLPLALKGTEVKVAVCDIDPEWLTANASPRAQGFLDGVTGTARDVQRLPFTQPM
                     AAG"
     misc_feature    2075..2091
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
     gene            2206..3465
                     /locus_tag="TU31_RS01600"
                     /old_locus_tag="TPA0598_01_03490"
     CDS             2206..3465
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603594.1"
                     /locus_tag="TU31_RS01600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03490"
                     /product="amidohydrolase"
                     /protein_id="WP_042149769.1"
                     /transl_table=11
                     /translation="MSREVSAARTPAGDQLPGALPEALRAELSAFRRDLHRHPELGNQE
                     FRTTATLKERLERAGLRPRVLATGTGLICDIGTRDATADGRAVAAAPDRPLLALRADID
                     ALPIPDTKTVDYASTVAGRAHACGHDVHTTVVLGAGLVLAELARTGALPRPVRLLFQPA
                     EEILPGGASDAIESGALEGVGRILAVHCDPRVDAGRIGLRTGAITSACDRLEVELDGPG
                     GHTARPHLTTDMVTAASRVALDVPALLARRVDARAGMAVTWGRLASGHACNVIPQHAEL
                     SGTVRCLDLDAWRRAPDLVHAAIDEIAALHGAKSQITYVRGVPPVVNEPVTVQLLHSAM
                     AARRGEGAIEDTEQSLGGEDFSWYLEDVPGAMVRLGVHPPADPTHRDLHRGDFDVDEQA
                     IKVGVELFTGCALLDGDLAD"
     misc_feature    complement(2231..2247)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.01"
                     /tool="antismash"
     gene            3769..4800
                     /locus_tag="TU31_RS01605"
                     /old_locus_tag="TPA0598_01_03500"
     CDS             3769..4800
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986626.1"
                     /locus_tag="TU31_RS01605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03500"
                     /product="BMP family protein"
                     /protein_id="WP_042147705.1"
                     /transl_table=11
                     /translation="MRRVIRIAAAATATAGLALTATACGQSFAEANRAKHAGVGLAFDI
                     GGRDDHSFNEAAARGADNATKKLGVNVKMLTAKNGETEADREQRLTSFAEAGYNPVIGV
                     GFAYSQAVQNVAKDFPATTFGVVDAVPEGKNVDAMVFAEHEGSYLAGVAAALKSKNHKV
                     GFIGGVNNALIQKFQAGFEQGVRDTDPKAKVTSQYLYPNNDKGFNDPAAAKAKAGGMLD
                     SGIDVIYTAAGQSGAGTIEAISRVKGAWAIGVDSDQYQQPGLARYKNRILTSVVKNVDV
                     AVFDLIKSAEDGKPLTGIHSYDLKHSGVSLATSGGFIKDIQPQIDAARKKIIEGKVKVK
                     ETP"
     gene            5021..6577
                     /locus_tag="TU31_RS01610"
                     /old_locus_tag="TPA0598_01_03510"
     CDS             5021..6577
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089184.1"
                     /locus_tag="TU31_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03510"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_107070598.1"
                     /transl_table=11
                     /translation="MANHDIHLTVRRGTVHALCGENGAGKSTLMKILYGMQKPDEGTIA
                     LGGEQVTLHTPGDAIARGIGMVHQHFMLADNLTVLENTVLGAEKLHGIGAGARAKIKEL
                     SDAYGLNIRPDVLVEDLGVADRQRVEILKVLYRGARTLILDEPTAVLVPQEVDALFDNL
                     RELKSEGLTVIFISHKLGEVLSVADDITVIRRGTTVASVEPSETTPKQLAELMVGSELP
                     SPETRESTVTDEEMLRVSDVHLSATDSDGVVRTVLDGISFTIHKGEVLGVAGVEGNGQA
                     ELVEAVMGTRRPDHGTITLDGTDLSGASTRARREGGIGYIPEDRHRHGLLLEAPLWENR
                     ILGHVTERPNSKGKLLDIPGARKDTERIVEQYDVRTPGIEVTASSLSGGNQQKLIVGRE
                     MSHHPKLLIAAHPTRGVDVGAQAQIWEQIREARREGLAVLLISADLDELIGLSDTLRVM
                     YRGRLVADADPAVITPEELGSAMTGAARGHLSASEDGASQEGTPEDGASHDAGEQEGDE
                     Q"
     gene            6574..7734
                     /locus_tag="TU31_RS01615"
                     /old_locus_tag="TPA0598_01_03520"
     CDS             6574..7734
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089185.1"
                     /locus_tag="TU31_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03520"
                     /product="ABC transporter permease"
                     /protein_id="WP_370682689.1"
                     /transl_table=11
                     /translation="MSTSTKNPTVDAIAKSATRDKVILAIAAPVLAIVAAIVISSLVFL
                     ASGENPFRAYGIMADYGHYSDSQVWIINKAVPYYLSALAVAIGFRMNLFNIGVDGQYRL
                     AAFAAAAVGGAIALPGALQIILLIVIAMLVGAIWSGIAGLLKTTRGVSEVITTIMLNAI
                     AASIIGYFLQDGRLAIKDGNLLHTRFLPESSHFFSFPTHPKPVLGFVVIAVLAGALYWF
                     GINRTRFGFDLRAVGASEPAAEASGVSVKRMVLCSMLLSGAAAGLVGMPTLLGESFQYG
                     TDFPAGIGFTGIAIALLGRNHPIGMAFGALLWAFLDRTGSRLEFEGYAQEIVGVMQGVI
                     VLCVVIAYEIVRRYGLSLQQRKVGEELAALSRTTNSDKSDKPEVSA"
     gene            7731..9011
                     /locus_tag="TU31_RS01620"
                     /old_locus_tag="TPA0598_01_03530"
     CDS             7731..9011
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089186.1"
                     /locus_tag="TU31_RS01620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03530"
                     /product="ABC transporter permease"
                     /protein_id="WP_042147711.1"
                     /transl_table=11
                     /translation="MSTDLKTATKLAVPGKGGRRKLTYPWILLIIAVGLVAVSVLRAVT
                     GAGDLTSTGQFGAALSAAVPIGLAGLGGLWSERAGVVNIGLEGMMMLGSFAAGWVGWQH
                     GPWAAAAAGVIGGALGGLIHAIATVTFGVDHIVSGVAVNILALGATQYLATLWFGQEGS
                     AAMLAGGNDKQSPPMPDMPTFTVPGLSDALNTLEGHHWFLVSDVAGILGAAVTNVSWLT
                     LLTVGLFIGTFYVLWRSSFGLRLRSCGEAPISAETLGVNVYSYKYAAVLVSGALAGLGG
                     AFLSIGVHFFQDGQTGGRGYIGLATMIFGNWRPGGVAMGAGLFGFMDAMQLRSGGPTVH
                     ALLLGLAALLAVLALLRLRALKRTQAVVAGIAAAVLVIWYFLADTVPLELVEASPYIAT
                     LLVLALFSQRLRPPKANGKPYRRGQGT"
     gene            9008..9427
                     /locus_tag="TU31_RS01625"
                     /old_locus_tag="TPA0598_01_03540"
     CDS             9008..9427
                     /EC_number="3.5.4.5"
                     /GO_function="GO:0004126 - cytidine deaminase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020397723.1"
                     /locus_tag="TU31_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03540"
                     /product="cytidine deaminase"
                     /protein_id="WP_042147715.1"
                     /transl_table=11
                     /translation="MTPPVPVDWTALRAQARDAMSRAYAPYSGYPVGAAALVDDGRTIT
                     GCNVENASYGLALCAECGLISELFAGRPDSTGPAPRLTAFTCVDGAGELLVPCGRCRQL
                     LWEHGGPELLVDTAAGIRPLSELLPDAFGAGHLRG"
     gene            complement(9490..9933)
                     /locus_tag="TU31_RS01630"
                     /old_locus_tag="TPA0598_01_03550"
     CDS             complement(9490..9933)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018843989.1"
                     /locus_tag="TU31_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03550"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_042147718.1"
                     /transl_table=11
                     /translation="MSDLRIQRPDGDDALKDWQFVHNTIIPTHLLSLEDVRERAQRHHL
                     EVAYAGDELIGCSTVRPPADDALTVTVIARVLEAHRGQGFGEELYARGLSRARELGAEV
                     IETVVLSSNEDGLRFARKHGFVEIERYLLPGDSIPWIDLRLAR"
     misc_feature    complement(9914..9928)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.18"
                     /tool="antismash"
     gene            complement(10001..11059)
                     /locus_tag="TU31_RS01635"
                     /old_locus_tag="TPA0598_01_03560"
     CDS             complement(10001..11059)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_p450"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089189.1"
                     /locus_tag="TU31_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03560"
                     /product="cytochrome P450"
                     /protein_id="WP_042147721.1"
                     /sec_met_domain="atropopeptide_p450 (E-value: 5.5e-186,
                     bitscore: 613.7, seeds: 287, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 9.7e-14, bitscore: 47.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVHRVGGSDRVIEFAPRIDELLSRYRGASLFRLEPDTIGVSGAE
                     LMDRLLRSRPANAEERPTFKPVQGRLVTRTDASTFMQAVGSDVRNALQRPLDEAVDLTG
                     RWPHVAHVYLRNLVFGNERLRFRVLVDRRLELTPKLTWSAVASGAALLGRPGQGVPLSK
                     LAALVLDSTTYSDRRYAMYLYRRVAAPVCFTVSALVTNALWLGAPFSDDVSNRNILLEA
                     LRLLPPSWNILRMASPEFSDVDARIGPKDDVLLLPLLSHRDPKLWDEPDAFHPDRWEEL
                     DGDNHPGYLPFGHVSERCWGRHMVLPLAERLLDIVRRDGLVVSPSQTRGKVELDGLLEV
                     SEVQMTRPRARP"
     misc_feature    complement(10910..10912)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10991..10993)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11103..11117)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            complement(11137..11292)
                     /locus_tag="TU31_RS40515"
                     /old_locus_tag="TPA0598_01_03570"
     CDS             complement(11137..11292)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038372.1"
                     /locus_tag="TU31_RS40515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03570"
                     /product="tryptorubin family RiPP precursor"
                     /protein_id="WP_370682690.1"
                     /sec_met_domain="atropopeptide_precursor (E-value: 1.0,
                     bitscore: 1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGIPPGLYIFCRRISISFATQMEVLMKLVRIVKKFRPEKSLKAY
                     AWYGWI"
     gene            12680..13957
                     /locus_tag="TU31_RS01645"
                     /old_locus_tag="TPA0598_01_03590"
     CDS             12680..13957
                     /EC_number="2.4.2.4"
                     /GO_process="GO:0006206 - pyrimidine nucleobase metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004943780.1"
                     /locus_tag="TU31_RS01645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03590"
                     /product="thymidine phosphorylase"
                     /protein_id="WP_042147727.1"
                     /transl_table=11
                     /translation="MDAISVIRTKRDRGELTPDQIDWVIDAYTRGEVAHEQMSSLAMAI
                     FLNGMNRTEIARWTAAMIASGERMDFSSLPRPTADKHSTGGVGDKITLPLAPLVAACGA
                     AVPQLSGRGLGHTGGTLDKLEAIPGWRATLSNDEMLNVLRDVGSVICAAGDGLAPADKK
                     LYALRDVTGTVESIPLIASSIMSKKIAEGTGSLVLDVKVGSGAFMKDLDNARELASTMV
                     ELGTDHGVKTVALLTDMATPLGLTAGNALEVRESVEVLAGGGPQDVVELTLALAREMLD
                     AAGLKDADPAKALADGSAMDHWRRMIAAQGGDPDAALPVAREQHVVTASSSGILTTLDA
                     YAVGLAAWRLGAGRARKEDPVQAGAGVELHAKPGDTVTAGQPLLTLHTDTPEKFPYALE
                     ALDGGVLVGPEDAAFAATPVVLERIA"
     gene            14058..14231
                     /locus_tag="TU31_RS38445"
                     /old_locus_tag="TPA0598_01_03600"
     CDS             14058..14231
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TU31_RS38445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TPA0598_01_03600"
                     /product="hypothetical protein"
                     /protein_id="WP_158894218.1"
                     /transl_table=11
                     /translation="MLKRRSPKWAPRGPAVTLHGDPEGDAYRTLSAVRFGEPMYLPAPF
                     DVTVDTALFPAD"
     gene            complement(14306..15622)
                     /locus_tag="TU31_RS01650"
                     /old_locus_tag="TPA0598_01_03610"
     CDS             complement(14306..15622)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603575.1"
                     /locus_tag="TU31_RS01650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03610"
                     /product="MFS transporter"
                     /protein_id="WP_042147730.1"
                     /transl_table=11
                     /translation="MPPADTGASVTDRAAASPQSSPDSSTAAALDPEAGKLRPGGPGYR
                     RMSFALFAAGVATFALLYSTQALLPAISADLGVSPDQASWTVSAATFGLALGVIPLSAV
                     SERFGRRTLMMWSLAVAALLAMLVPFAPSLGVLIALRGIQGVALAGLPASAMAFLAEEV
                     RAKALVAAIGLFVAGNSIGGMSGRIVTGWVAQAWGWRAALAAVGVLAVVCAVAFRLLVP
                     KARHFVSRSVGPRALARTLGSHLADPLLRRLYAIGGLFMTVFGAVYTVIGYRLVSEPFN
                     LPQGIVGSIFVVYLVGTVSSAAAGKLVARVGRRGALYLAVGTTSTGLLLTLSASVGAVL
                     AGLILITAGFFAGHAVASSSVSRTAKTARAQASALYQCAYYVGSSLGGALGAAAFHAVG
                     WEGTVLLGLAAMLGAASITLYATRKAVAERRLLHLEKAA"
     gene            15718..16701
                     /locus_tag="TU31_RS01655"
                     /old_locus_tag="TPA0598_01_03620"
     CDS             15718..16701
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603574.1"
                     /locus_tag="TU31_RS01655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03620"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_370682691.1"
                     /transl_table=11
                     /translation="MQGRNRKDTAGSGRAGVDTGEVAELGADSWAVTLAPRLAQFTAVA
                     RHEHVTRAAQELGMPQPTLSRAIVRLEEDLGVALFARHGRTLSLTPAGRAFLAATERAL
                     TDLERATESVRADVDPAAGKVAFGFLHTLGSETVPGLIRSFRADHPRVRFQLVQNYGEA
                     MIERLRAGDLDLCLTSPVPDYPDLVARRLDEQKLRLVVPDDHPLAARKRIRLAEAAGEL
                     FVTLEPGYGLRRITDALCAEAGFTPRVAFEGEEAETLRGLVAAGLGVALLPPPAVPRPG
                     VAELTVTAPRAVREIGVAWLDGHPDTPPVAAFKKFLLSRRGRLLPR"
     gene            complement(16821..17636)
                     /locus_tag="TU31_RS01660"
                     /old_locus_tag="TPA0598_01_03630"
     CDS             complement(16821..17636)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061321.1"
                     /locus_tag="TU31_RS01660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03630"
                     /product="dienelactone hydrolase"
                     /protein_id="WP_042147735.1"
                     /transl_table=11
                     /translation="MAQQALPVREARLGKPLGTAGKEGAREALRWKGGRRGTGREVSGV
                     ALLLPGGGPTGVRRPSPVAALAVRPLAVRLAKAGRPEGLTAHVVRYRCHGWNGAAAHPA
                     RDADWALEEVVRRYGDVPVCLVGTGMGARAALHAAGHPAVNSVLAIAPWLPDPHRDSEP
                     PDPVKQLIGRQVLLVHGTNDERTDPDLSYRYAERAKKVNRDICRFEVHSDGHSLHQHRA
                     EVLALATDFMLGSLFARGYARPVKDALAAPPPLGLRMPLAAGFGASLRQ"
     misc_feature    complement(17493..17495)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17740..18900
                     /locus_tag="TU31_RS01665"
                     /old_locus_tag="TPA0598_01_03640"
     CDS             17740..18900
                     /EC_number="3.5.4.4"
                     /GO_function="GO:0004000 - adenosine deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009168 - purine ribonucleoside
                     monophosphate biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089202.1"
                     /locus_tag="TU31_RS01665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03640"
                     /product="adenosine deaminase"
                     /protein_id="WP_042147738.1"
                     /transl_table=11
                     /translation="MTSETTTLPTSEQIRRAPKVLLHDHLDGGLRPATIVELAREIGYE
                     GLPETDPEKLGVWFREACDSGSLERYLETFAHTCAVMQTRDALVRVAAECAEDLAADGV
                     VYAEVRYAPEQHLEQGLTLEEVVEAVNEGFREGERRARENGHRIRVGALLTAMRHAARA
                     LEIAELANRYRDTGVAGFDIAGAEAGYPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSI
                     WQALQWCGADRLGHGVRIIDDIEVADDGSVKLGRLASYVRDKRIPLEMCPTSNLQTGAA
                     PSYAEHPIGLLRRLQFRLTVNTDNRLMSHTSMTEEFEHLVKTFRYTLDDMQWFTVNAMK
                     SAFIPFDERLAMINDVIKPGYAELRAEWLFRPAATTPPANSTSDSA"
     gene            19042..19317
                     /locus_tag="TU31_RS01670"
                     /old_locus_tag="TPA0598_01_03650"
     CDS             19042..19317
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089203.1"
                     /locus_tag="TU31_RS01670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03650"
                     /product="hypothetical protein"
                     /protein_id="WP_042147742.1"
                     /transl_table=11
                     /translation="MKQGTIKTLGTVALGAAFVVTAAGVASAAPSVDTAGVLKSLPVKD
                     ATKTVSGLTKSKPAGNDVKTKLNSQGNKLLGGLPTSAVTKTLPLGG"
     misc_feature    19057..19071
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    complement(19086..19102)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.28"
                     /tool="antismash"
     gene            complement(19475..19687)
                     /locus_tag="TU31_RS01675"
                     /old_locus_tag="TPA0598_01_03660"
     CDS             complement(19475..19687)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089204.1"
                     /locus_tag="TU31_RS01675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03660"
                     /product="PspC domain-containing protein"
                     /protein_id="WP_042147745.1"
                     /transl_table=11
                     /translation="MAAALVRPSNNRMIAGVCAGLARRFGMTPKTMRVLFVVSCLLPGP
                     QFLVYLALWILLPSEEKAATGAAAW"
     gene            complement(19732..20247)
                     /locus_tag="TU31_RS01680"
                     /old_locus_tag="TPA0598_01_03670"
     CDS             complement(19732..20247)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004571969.1"
                     /locus_tag="TU31_RS01680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03670"
                     /product="VanZ family protein"
                     /protein_id="WP_181018536.1"
                     /transl_table=11
                     /translation="MRVTGLLLLVAHLLIVAWLTLRPRTVPWVSATNLEPLATIRAELA
                     YGPSWDAVQHLGGSVLLLAPLGVLLPLSAGRLNVSPLVSLTRTVFAGAMISLAIELLQS
                     GVPGRVPDIDAVLLGSLGVALAHLAVVPGARRRLRRRYGDLGEATPRIPRVELAPQADV
                     LSGSRTYL"
     gene            complement(20353..20979)
                     /locus_tag="TU31_RS01685"
                     /old_locus_tag="TPA0598_01_03680"
     CDS             complement(20353..20979)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571667.1"
                     /locus_tag="TU31_RS01685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TPA0598_01_03680"
                     /product="hypothetical protein"
                     /protein_id="WP_042147751.1"
                     /transl_table=11
                     /translation="MTPIRRTGRRTAAVAALTLVAAGCGIRGTSVPVDAGGAPSRVSCK
                     APASEPAPNPPGRSQATVYLVCGSALAQVERAVSLPKGSATTDPRLPAARALLKELQRQ
                     PSSDEDRAGFSTALPQDLKVTAPRAGDAADTLRLSIRPEDLPSFALAQLVCTYGASPVL
                     GKQHAAVLGGPGDATAHRYDCSADVLANPDIAENAGWGDPLTEED"
ORIGIN
        1 cgttcgcgct gatcgacgcc gccgccgacg ccggctgtga cgcggtgaag ttccagaagc
       61 gcacccccga ggtctgcacc ccgcgcgacc agtgggagat cgagcgcgac accccctggg
      121 gccggatgac ctacatcgac taccgccacc gcgtggagtt cgacgaggag ggctaccgcg
      181 ccatcgacga gtactgcaag aagcgcggca tcgcctggtt cgcctccccg tgggacgtcg
      241 agtccgtcgc cttcctggag aagttcgacg tgccctgcta caaggtcgcc tccgcctcgc
      301 tcaccgacga cgagctgctg cgcgccatgc gcgccaccgg ccgcaccgtc atcctctcga
      361 cgggcatgtc cacccccaag cagatcaggc acgccgtcga ggtcctgggc agcgagaaca
      421 tcctgctctg ccacgccacg agcacctacc cggccaaggc cgaggagctc aacctccgca
      481 tgatcaacac ccttcaggac gagtacccga acgtcccgat cggctacagc ggccacgaga
      541 ccggtctcca gaccaccctc gccgcggtcg ccctcggcgc caccttcgtc gagcgccaca
      601 tcaccctcga ccgcgccatg tggggctccg accaggccgc ctccgtcgag cccggcggcc
      661 tgtcccgcct ggtccgcgac atccgcacca tcgaggagtc cctcggtgac ggcgtcaaga
      721 aggtctacga gagcgagctc ggcccgatga agaagctgcg ccgcgtcacc ggcgtggtgg
      781 ccgaggccga ggccgccgag ccggccgccg tctgaccgcc cggccgacga accgacggga
      841 gccaaggtga cctcacctga ggggacccgc gccgtgcccg gcacgcccgg cgccgaggtt
      901 ccgcccccgg agacgacgga tactcccgcc cgtcgtctcc ggggggtgcc gcggcagcgt
      961 caccggaccg cacgctccgg tgagccgcga gcggccgccc gggacaccgg caccctcgcg
     1021 ttcgtcgaga gcccggtgca gctgctgaac gtcctggagt gggcgcacac cgcacaggcc
     1081 accgggctca ccgtcgtcgt gctctccccg caggatccga tgacccgcgg ccagctgcgg
     1141 cggatggccg aactcgcccg cgacgaaggc catacggtgc gctgggagga ggcccgcggt
     1201 ggtccgaccg cgccgatgcg caccatcggc ggcctcaccc cgctgctgcg ccgcgcccac
     1261 cgcgtcgtca tcggcgaccc gttctcccgc tacgtccagc tgctgctctc cctcgccagg
     1321 gcgcgcgatc tggtcgtggt cgacgacggc accgccacca tggagttcat ctcccaactc
     1381 gcccgcgggg aacagctggt gcgctggcac cgcaacggca gcggccgcgg cccgcgggac
     1441 ctgatcttcg ccccgttctc ggccaccgcc cggcgccggc tcaccccggc tcccgagggc
     1501 gggcggcgca ccgtcggcct gttcagctcg atgcccgtcg aggcgccgcc gggcgtcgag
     1561 gtcaccacca acgagttcgc ctggacccgg agccgcttcg gcccgccccg gctcacccgc
     1621 gccgccgaca tcgtcggcac ctcgctggtg gagaccgggg tcgtggacgc cgagcgctac
     1681 ctggcggcgg tcgccggcct ggcccgtacg cacggcgcca cccgctactt cgcgcaccgc
     1741 aaggagagca ccgagaagct gcgccggctc gtgggcgaga ccgggctgga gatcgtccgg
     1801 cccgatctgc cgctcgaact gatcgcccgg cgcgggccca tcggacggct gatcgtcagc
     1861 ttcccctcca ccgtggtcca caccctgccg ctggcgctga aggggacgga ggtcaaggtc
     1921 gcggtctgcg acatcgatcc ggagtggctg acggccaacg cctcaccgcg ggcccagggt
     1981 ttcctcgacg gggtcaccgg caccgcccgc gacgtgcagc gactgccctt cacccagccg
     2041 atggccgccg gatgaaggag cgcgggaagc cttactgcat acccgtcgca taaaccgtcc
     2101 atgcgccgag cggcctgatt ttcttcccct aacgggctga acttttgttg atcgaaggac
     2161 agttgccccc ttcgggcccg taaccttcca caggtgaacc acgtgatgtc ccgagaggtc
     2221 agtgccgccc gtacccccgc cggggatcag ctccccggcg cccttcccga ggccctgcgc
     2281 gccgaactca gcgccttccg gcgcgacttg caccggcacc cggaactcgg caaccaggag
     2341 ttccggacca ccgcgacgct caaggaacgg ctggagcggg ccggactgcg gccccgggtg
     2401 ctggccaccg gcaccggcct gatctgtgac atcggcaccc gggacgccac ggccgacggg
     2461 cgggccgtag cggccgcccc cgaccgcccc ctgctggcgc tgcgggcgga catcgacgcg
     2521 ctgccgatcc cggacaccaa gaccgtcgac tacgcctcga cggtcgccgg ccgcgcccac
     2581 gcctgcggcc atgatgtgca caccaccgtc gtcctcggcg ccggtctggt cctggccgag
     2641 ctggcccgca ccggcgccct gccgcgcccc gtgcgcctgc tcttccagcc cgccgaggag
     2701 atcctgcccg gcggcgcctc cgacgcgatc gagtccggcg ccctggaggg cgtcggccgg
     2761 atcctcgccg tccactgcga cccgcgggtc gacgccggcc ggatcgggct ccgtacggga
     2821 gcgatcacct cggcctgtga ccggctggag gtcgagctgg acggccccgg cggccacacc
     2881 gcccgcccgc acctgaccac cgacatggtc accgccgcct cccgggtcgc cctggacgta
     2941 ccggcgctgc tggcccgccg ggtcgacgcc cgcgccggta tggccgtcac ctggggccgg
     3001 ctggcgtccg ggcacgcctg caacgtcatc ccgcagcacg ccgaactctc cggcaccgtc
     3061 cgctgtcttg atctcgacgc ctggcggcgg gccccggacc tggtccatgc ggcgatcgac
     3121 gagatcgccg cgctgcacgg cgcgaagtcc cagatcacct acgtccgcgg ggtgccgccg
     3181 gtggtcaacg agccggtcac cgtccagctg ctgcactccg cgatggccgc ccgccgcggc
     3241 gagggcgcca tcgaggacac cgagcagtcc ctcggcggcg aggacttctc ctggtacctc
     3301 gaagacgtcc ccggcgccat ggtccgcctc ggcgtccacc cgcccgccga ccccacgcac
     3361 cgggacctgc accgcggcga tttcgacgtg gacgagcagg cgatcaaggt gggcgtggag
     3421 ctcttcaccg gctgcgcgct cctcgacggg gacctcgcgg actgaggacg gactgagcac
     3481 gggctgagcg cagtgggtcc gggcggcgtc gcacggcgac cggcccggcc agtcccccgc
     3541 ccgacccgtc ccctatagcg ggacactgtc cgtaatgact ccataacgac ccgttccggc
     3601 agcttgccgg gacgggccgc gcggcccgtc cccccgtgtt tcgttcaggt gccctacgcc
     3661 tcgaatcgat aacgtccacg cagtggaggg ttttgcgcca ggtctacgcg cgttaatctc
     3721 ccgacaagcc agcgccaatg ggggcgctta gagcgaaggg aaggccccgt gcgtcgggtc
     3781 atcaggattg ccgccgcggc caccgccacc gcgggcctcg cgctcaccgc caccgcgtgc
     3841 ggtcagagct ttgccgaggc caaccgcgcc aaacacgcgg gggtcgggtt ggccttcgac
     3901 atcggcggcc gggacgacca ctcgttcaac gaagcggccg cccgcggtgc ggacaacgcg
     3961 accaagaagc tgggcgtcaa cgtcaagatg ctcaccgcca agaacggcga gaccgaggcg
     4021 gaccgcgagc agcggctcac ctccttcgcc gaggccggct acaacccggt catcggcgtc
     4081 ggcttcgcct acagccaggc cgtgcagaac gtggccaagg acttccccgc caccaccttc
     4141 ggtgtcgtgg acgccgtgcc cgagggcaag aacgtcgatg cgatggtctt cgccgagcac
     4201 gagggctcgt atctggccgg ggtcgcggcc gcgctgaaga gcaagaacca caaggtgggc
     4261 ttcatcggcg gcgtgaacaa cgcgctgatc cagaagttcc aggccggctt cgagcagggg
     4321 gtccgtgaca ccgacccgaa ggccaaggtc acctcgcagt acctgtaccc caacaacgac
     4381 aaggggttca acgacccggc ggccgccaag gccaaggccg gcggcatgct cgacagcggg
     4441 atcgacgtga tctacacggc ggccgggcag tcgggcgccg ggaccatcga ggcgatcagc
     4501 agggtcaagg gcgcctgggc gatcggcgtg gactcggacc agtaccagca gccgggtctg
     4561 gcccgctaca agaaccggat cctcacctcg gtcgtgaaga acgtcgatgt ggccgtgttc
     4621 gacctgatca agagcgccga ggacgggaag ccgctgaccg gcatccactc ctacgacctc
     4681 aagcacagcg gggtgtcgct cgccacctcg ggcgggttca tcaaggacat ccagccgcag
     4741 atcgatgcgg cccggaagaa gatcatcgag ggcaaggtga aggtcaagga gacgccgtag
     4801 cccgggacca ccgccgcccc gggtctccgc agcgccggac cccgggggcg agccccacgt
     4861 ccccccttgt gaccttccgg tccctgactt tccgtccttt ccgctccttc atccctgagg
     4921 ggagtgcgcc atcaacgcag catccacgag cagcggcccc gccgtcccgg acgcccccgc
     4981 tgtagaactc cgcggaatca ccaaaaggtt ccccggcgtc gtggccaacc acgacatcca
     5041 tctcaccgtg cgccgcggca ccgtccacgc cctgtgcggc gagaacggtg ccggcaagtc
     5101 caccctgatg aagatcctct acggcatgca gaagccggac gagggcacca tcgcgctggg
     5161 cggcgagcag gtcaccctgc acaccccggg cgacgccatc gcgcgcggca tcggcatggt
     5221 gcaccagcac ttcatgctcg ccgacaacct caccgtcctg gagaacaccg tcctcggcgc
     5281 ggaaaagctg cacggcatcg gcgccggcgc ccgcgcgaag ataaaggaac tctccgacgc
     5341 gtacgggctg aacatccggc ccgacgtcct ggtcgaggac ctcggtgtcg ccgaccgcca
     5401 gcgggtggag atcctcaagg tcctctaccg cggcgcccgc acgctcatcc tcgacgagcc
     5461 gactgccgtc ctggtcccgc aggaggtcga cgcgctcttc gacaacctgc gtgagctcaa
     5521 gtccgagggc ctgaccgtca tcttcatctc gcacaagctg ggcgaggtgc tctcggtcgc
     5581 cgacgacatc accgtcatac ggcgcggcac caccgtggcc tcggtcgaac cgtccgagac
     5641 cacccccaag cagctggccg agctgatggt cggcagcgaa ctgccgtcac ccgagacccg
     5701 cgaatcgacc gtcaccgacg aggagatgct ccgcgtcagc gacgtccacc tctccgcgac
     5761 cgactccgac ggcgtggtcc gcaccgtcct ggacggcatc tccttcacca tccacaaggg
     5821 cgaggtgctg ggcgtcgccg gtgtcgaggg caacggccag gccgagctcg tcgaggccgt
     5881 catgggcacc cgccgccccg accacggcac gatcaccctg gacggcacgg acctgtccgg
     5941 cgcctccacc cgcgcccggc gcgagggcgg catcggctac atccccgagg accgccaccg
     6001 ccacggcctg ctgctggaag ccccgctgtg ggagaaccgc atcctgggcc atgtcaccga
     6061 gcgccccaac agcaagggca agctcctcga catccccggc gcccgtaagg acaccgagcg
     6121 catcgtcgag cagtacgacg tgcgcacccc cggcatcgag gtcaccgcgt cctcgctctc
     6181 cggcggcaac cagcagaagc tgatcgtcgg gcgcgagatg agccaccacc ccaagctgct
     6241 gatcgccgcg caccccaccc gcggggtcga tgtcggtgcg caggcgcaga tctgggaaca
     6301 gatccgcgag gcgcgccgcg agggcctggc ggtgctgctg atctctgccg acctggacga
     6361 gctgatcggg ctgtccgaca ccctgcgggt gatgtaccgg ggccggctgg tcgcggacgc
     6421 ggaccccgcc gtcatcaccc cggaggagtt gggctccgcc atgaccggtg ccgccagagg
     6481 ccacctcagt gcttcggaag acggtgcgtc gcaagagggc acaccagaag acggtgcgtc
     6541 gcacgacgcc ggtgagcagg agggcgacga gcagtgagca cctccaccaa gaaccccacc
     6601 gtggacgcca ttgccaagag cgccacccgc gacaaggtga tcctcgcgat cgccgcgccc
     6661 gtcctggcca tcgtcgccgc gatagtgatc tcgtccctgg tgttcctcgc ctcgggcgag
     6721 aaccccttcc gggcctacgg gatcatggcc gattacggcc actacagcga cagccaggtc
     6781 tggatcatca acaaggcggt gccgtactac ctttcggcgc tggcggtcgc catcggcttc
     6841 cgcatgaacc tcttcaacat cggcgtcgac ggccagtacc gcctcgcggc cttcgccgcc
     6901 gcggccgtgg gcggcgccat cgccctcccc ggcgcgctcc agatcatcct gctcatcgtc
     6961 atcgcgatgc tggtgggcgc catctggtcg ggcatcgcgg gtctgctgaa gaccacccgc
     7021 ggcgtcagcg aggtgatcac cacgatcatg ctgaacgcca tcgccgcgtc gatcatcggc
     7081 tacttcctcc aggacggccg cctcgccatc aaggacggca acctcctgca caccaggttc
     7141 ctgccggagt ccagccactt cttctccttc ccgacccacc ccaagccggt cctcggcttc
     7201 gtggtgatcg cggtcctggc cggggcgctc tactggttcg ggatcaaccg cacccgcttc
     7261 ggcttcgacc tgcgcgccgt gggcgcctcc gagccggccg ccgaggccag cggggtcagc
     7321 gtcaagcgga tggtcctgtg cagcatgctg ctgtcgggcg ccgcggccgg tctggtcggt
     7381 atgcccaccc tgctcggtga gtccttccag tacggcacgg acttcccggc cggtatcggc
     7441 ttcaccggta tcgccatcgc gctgctcggc cgcaaccacc ccatcggcat ggccttcggt
     7501 gccctgctgt gggcgttcct cgaccgcacc ggctcccggc tggagttcga gggctacgcc
     7561 caggagatcg tcggcgtcat gcagggcgtc atcgtcctct gcgtggtcat cgcctacgag
     7621 atcgtgcgcc gctacgggct gagccttcag cagcgcaagg tcggcgagga gctggccgcc
     7681 ctgtcccgca cgacaaactc tgacaagagc gacaagccgg aggtgtcggc gtgagtacgg
     7741 acctcaagac cgcgacgaag ctcgcggtcc ccgggaaggg cggccggcgc aagctgacct
     7801 acccctggat cctgctgatc atcgccgtcg ggctggtcgc cgtctctgtc ctccgggccg
     7861 tcaccggtgc cggtgacctc acctccaccg gccagttcgg cgccgcactg agcgccgccg
     7921 tgccgatcgg cctggcgggt ctgggcggac tgtggtccga gcgggccggc gtggtcaaca
     7981 tcggcctcga aggcatgatg atgctcggct cgttcgcggc cggctgggtc ggctggcagc
     8041 acggcccctg ggcggcggcc gcggccggcg tcatcggcgg cgcgctcggc ggcctcatcc
     8101 acgccatcgc caccgtcacc ttcggtgtcg accacatcgt ctccggtgtc gcggtcaaca
     8161 tcctggcgct cggtgccacc cagtacctgg ccacgctgtg gttcggccag gagggcagcg
     8221 cggccatgct ggccggcggc aacgacaagc agtcgccgcc gatgcccgac atgccgacgt
     8281 tcaccgtccc cggcctgtcg gacgcgctga acaccctgga gggccaccac tggttcctgg
     8341 tctccgacgt cgccggcatc ctcggtgccg cggtcaccaa cgtctcctgg ctgaccctgc
     8401 tcaccgtcgg cctgttcatc ggcaccttct acgtactctg gcgctcctcg ttcggactgc
     8461 ggctgcgctc ctgcggcgag gccccgatct cggccgagac cctgggcgtc aacgtctact
     8521 cgtacaagta cgcggcggtg ctggtctccg gcgccctggc cggcctcggc ggtgccttcc
     8581 tctccatcgg agtgcacttc ttccaggacg gccagaccgg cggccgtggc tacatcggtc
     8641 tcgccacgat gatcttcggc aactggcggc cgggcggcgt cgcgatgggc gcgggcctgt
     8701 tcggcttcat ggacgccatg cagctgcgca gcggcggccc gaccgtccac gcactgctgc
     8761 tgggcctggc cgccctcctc gcggtgctcg ccctgctccg gctgcgcgcc ctcaagcgca
     8821 cccaggccgt ggtcgccggc atagccgccg ccgtcctggt catctggtac ttcctggccg
     8881 acaccgttcc gctcgaactg gtcgaggcga gcccgtacat cgccaccctg ctggtactcg
     8941 ccctcttctc ccagcggctg cggccgccga aggcgaacgg caagccctac cgccgaggac
     9001 aaggcacatg acaccaccgg tgccggtcga ctggaccgca ctgcgcgcgc aggcccggga
     9061 cgcgatgtcc cgggcctacg ccccgtattc cggctacccc gtaggcgccg ccgccctcgt
     9121 ggacgacggc cgcaccatca ccggctgcaa cgtggagaac gcctcctacg gcctggccct
     9181 ctgcgccgaa tgcggcctga tctcagaact gttcgccggc cgccccgaca gcaccggccc
     9241 ggccccccgg ctgaccgcct tcacctgcgt ggacggggcg ggcgaactgc tcgtcccctg
     9301 cggccgctgc cgccagctcc tgtgggaaca cggcggcccg gagcttctgg tggacacggc
     9361 ggcgggcatc cgcccgctgt cggagctgct gccggatgcg ttcggggcgg ggcatttgag
     9421 ggggtgaacg ggggcgggtg ggtgccagtg actccatccc cgccacccac cgcccccggc
     9481 accacccgct caccgggcaa gacgcaggtc gatccaggga atgctgtccc ccggcagcag
     9541 atagcgctcg atctcgacaa acccgtgctt gcgcgcgaac cgcagcccgt cctcgttgga
     9601 ggacagcacc acggtctcga tcacttcggc gcccaactcc cgcgccctgc tgagcccgcg
     9661 cgcatacagc tcctccccga acccctgacc acgatgagct tccagcacac gagcgatcac
     9721 ggtcaccgtc agcgcgtcat cggcgggcgg gcgcaccgtg ctgcatccga tgagctcgtc
     9781 accggcatac gcgacctcca agtggtgacg ctgcgcccgc tcccgcacat cctccagcga
     9841 aaggaggtgg gtagggatga tcgtgttgtg gacgaactgc cagtccttga gggcgtcgtc
     9901 gccatccggc cgctgaatac gaagatcaga catcgcagca gaacagccga gtccctcccg
     9961 cacgtcaact ccgtttcagg tgggacgaat ggtcaggccg tcacggtcga gccctcggtc
    10021 gagtcatctg cacttcggac acttcgagca atccgtcgag ttcgaccttc cccctggtct
    10081 ggctcggact caccaccagg ccgtcccgtc gcacgatgtc caggagccgt tcggccaggg
    10141 gcaggaccat atgccggccc cagcatcgtt cgcttacgtg gccgaagggg agatatccgg
    10201 ggtggttgtc tccgtccagc tcttcccagc ggtcgggatg aaacgcgtcg ggctcgtccc
    10261 agagcttggg gtcgcggtgg ctcagcaggg ggagcaacag gacatcgtct ttcgggccga
    10321 tccgtgcgtc cacgtccgag aactccggag aagccattcg caagatgttc catgaggggg
    10381 gaagcagtcg gagtgcctca aggaggatgt tccgattcga tacgtcatcg ctgaacggag
    10441 ccccgagcca cagggcgttg gtgaccagcg cggatacggt gaagcacacc ggtgctgcca
    10501 cccgccggta caggtacatg gcatagcgcc ggtcactgta ggtcgtggaa tcgagcacga
    10561 gagcggcaag ttttgacagc ggcacgccct gcccgggcct gcccagcaaa gcggcaccgg
    10621 aggcgacggc cgaccaggtc agtttcggtg tcaactccag cctgcggtcg accagaaccc
    10681 ggaatcgcag acgttcgttc ccgaaaacga gattccgcag gtaaacatgc gccacatgcg
    10741 gccagcggcc ggtcaggtcg accgcctcat cgaggggacg ttgcagcgcg ttccgcacgt
    10801 ccgagcccac ggcttgcata aaggtggacg catccgtacg ggtaacgagc cgcccctgga
    10861 cgggtttgaa ggtgggcctc tcctccgcgt tggccggcct gctacggagt aagcggtcca
    10921 tcagctcggc gccggacacc ccgatcgtgt cgggctccag acgaaaaagc gacgcaccac
    10981 gataacgact taacagttcg tcgattctcg gcgcgaactc gatgacccga tcgctcccgc
    11041 cgacgcggtg cacaggcata ggtgaactcc gtgggtaggc agctcgcgcc ggccagaatt
    11101 cctgaccgac gcgatcccgg cagggaaact gtctggttaa atccagccgt accaggcgta
    11161 tgccttgagg ctcttttccg ggcggaactt cttgacgatg cgaacgagtt tcatgagcac
    11221 ctccatttgc gtggcgaacg agatacttat gcgacggcag aagatgtaga gaccgggtgg
    11281 aattcccggc attcatttca actgctgtgg aaagtgaaga cctattcagt gaatgtgtca
    11341 agtgatccac atcactacct gaattgcctc attcacgttt cgaattcatc cgtattcgca
    11401 tctcggcaaa tcgccactaa tccatctatt gacacccaat gtgggcatcg aaagggggtg
    11461 gatggcgtcg aatggggtgg tttggtcatg gattatgtga catggacatg ttctgtaggg
    11521 cgggtcgagg gcctccggtc cccgctccgg cgcgatggct ctcccacacg gagaatcgcg
    11581 aagcggcggt gaagccggcg cagtcggtcg tctcggcacg gctcgcagca gccggggcgc
    11641 agatcgtcgg gcccggcggg gtcggtgcgc cggcatcagg gcgagttcgg ctcgggcgag
    11701 gaatggcacc tcgtcctcag gtctgggcga gttccagtac ctcggccact gcgggcagtt
    11761 cacgatgaga gccgtgaacc atcgaccgtc gagcacgacc cgggggaccg gtaccgcggt
    11821 aaacccggtg cctgccctgc ccggacgttg ctagcttcga cgcgtcggag accgcgggat
    11881 ctcgtccgaa acaggggtgc cggcgacatg tccgtagcag ctccgtccgg gggaacgtca
    11941 ccggtacgtg actacctgga ggcggtcctg gatctgctgg aggaacacgc gctcaaccgc
    12001 gaccggatgg actgggcgcg ggtacagcgg gcagcggagg cgcagatcgc ggacgcgacc
    12061 gcgacggaac agacctacgg ggtcatcgac gctgtgctcg acctgctggg ggatccgcac
    12121 accttcttcc tccgccctca ggacgccgag aagatgtgcg accaacaggc cacgcgggcc
    12181 gagccggtgc ccaccggacg gctgatcgac gggggggggg cgcgcacctc accgtcccgg
    12241 aggccgaggg ggtcacggag gcggagcggc ggtgctcggc aggccgcggg tacggacctt
    12301 cggggcgccc actgccggac tggcgaccgg gaacgtcgcc atcgacctga ccgatggcgc
    12361 cgttctcgtt ctcacagtgg cccgcgaggc cgatcggacc ggccgtctct acggcaacac
    12421 tcccatcgct ccggaccagc ccacgcccgg ggatgccgat gcgctcaccg acgccgtggc
    12481 gtggctccgg tccgtccggt ccccgtccgc agggggagcc gggcgaacgg atgaggccgt
    12541 cagctgccga agccgcggtc tccggccggt ggcggtgccc agcgcagtcg cccgcgggcg
    12601 actgcccctc ccggccctcc ctggccaccc cggcatctat gcgtgtagaa cgtacctacc
    12661 cgttcgaaag gaaccgtcca tggacgccat ctccgtcatc cgcaccaagc gcgaccgcgg
    12721 tgagctgacc cctgatcaga tcgactgggt catcgacgcc tacactcgcg gcgaggtcgc
    12781 ccacgagcag atgtcgtcgc tggcgatggc gatcttcctc aacggtatga accgcacgga
    12841 gatcgcccgc tggacggccg cgatgatcgc ctccggcgag cgcatggact tctcctccct
    12901 gccccgcccc accgccgaca agcactccac cggcggcgtc ggcgacaaga tcaccctccc
    12961 gctcgccccg ctcgtcgccg cctgcggcgc ggccgtcccg cagctctccg gccggggcct
    13021 cggccacacc ggtggcaccc tcgacaagct cgaagccatc cccggctggc gcgcgaccct
    13081 ctccaacgac gagatgctga acgtcctccg cgacgtcggc tccgtcatct gcgccgccgg
    13141 tgacggcctc gcccccgctg acaagaagct ctacgcgctg cgcgatgtca ccggcaccgt
    13201 cgagtccatc cccctcatcg cctcctcgat catgtccaag aagatcgccg agggcaccgg
    13261 ctccctcgtc ctggacgtca aggtcggctc cggtgccttc atgaaggacc tcgacaacgc
    13321 ccgtgaactg gcctccacca tggtcgagtt gggcaccgac cacggggtga agaccgtcgc
    13381 cctgctcacc gacatggcca ccccgctcgg cctgaccgcc ggcaacgccc tcgaagtccg
    13441 ggaatccgtc gaggtgttgg ccggtggcgg cccccaggac gtcgtcgagc tgaccctggc
    13501 gctggcccgc gagatgctcg acgcggccgg tctcaaggac gccgacccgg ccaaggcgct
    13561 ggccgacggc tccgccatgg accactggcg ccgcatgatc gcggcccagg gcggcgaccc
    13621 cgacgcggcc ctccccgtgg cccgcgaaca gcatgtcgtc accgcctcgt cctccggcat
    13681 cctcaccacc ctcgatgcct acgccgtggg tctcgccgcc tggcgcctcg gcgccggccg
    13741 cgcccgtaag gaggacccgg tccaggccgg cgcgggcgtg gaactgcacg ccaagccggg
    13801 cgacaccgtc accgcgggcc agcccctgct gaccctgcac accgacaccc cggagaagtt
    13861 cccctacgcc ttggaggccc tcgacggcgg cgtcctcgtc ggccccgagg acgcggcctt
    13921 cgccgccacc ccggtggtgc tggaacgtat cgcctgacct gggcccgcgg ccggaggccg
    13981 ctgatgacac ggctcggatg ggtgaacggg atcggcggac cggcgccggt cccgttcggc
    14041 gtggtgcagt cgggtgtgtg ctgaagagga ggagcccgaa gtgggccccg cgcggcccgg
    14101 cggtcactct ccacggcgac cccgagggcg atgcctatcg gacgctgagc gccgtcaggt
    14161 tcggcgaacc gatgtatctt cccgccccct tcgacgtcac cgtcgacacc gcactcttcc
    14221 ccgcggactg aggaaccgac gccgaaggcg aaaggcccgc cccaccagga caggtggcag
    14281 gacgggccct tcggactgcg ggtggctacg cggccttctc caggtggagg aggcggcgtt
    14341 cggccacggc cttgcgggtg gcgtagaggg tgatcgaggc ggcgccgagc atcgcggcga
    14401 ggccgaggag gacggtgccc tcccagccga cggcgtggaa ggcggcggcg ccgagcgcgc
    14461 cgcccaggct gctgccgacg tagtacgcgc actggtacag cgccgacgcc tgggcgcgcg
    14521 ccgtcttggc ggtgcggctg accgaggacg aggccaccgc atggcccgcg aagaaaccgg
    14581 cggtgatcag gatcaggccc gccagcaccg cgcccaccga agcggagagc gtcagcagca
    14641 gacccgtgga ggtggtgccg acggccaggt acagggcgcc gcggcggccc acccgggcga
    14701 ccagctttcc ggccgcggcc gaggagaccg taccgaccag gtagaccacg aagatcgaac
    14761 cgacgatgcc ctgcgggagg ttgaacggct cggagaccag gcggtagccg atgaccgtgt
    14821 agaccgcgcc gaagaccgtc atgaacagcc cgccgatggc gtagagacgg cgcagcagcg
    14881 ggtcggcgag gtggctgccg agcgtacggg ccagcgcccg cgggcccacc gaacgggaca
    14941 cgaagtgccg ggccttgggg accagcagcc ggaaggccac cgcgcacacc acggccagca
    15001 cacccaccgc ggcgagcgcc gcccgccagc cccacgcctg ggcgacccag cccgtcacga
    15061 tccggccgga catcccgccg atgctgttgc ccgccacgaa cagcccgatg gccgccacca
    15121 gagccttggc ccgtacctcc tcggccagga acgccatcgc cgaggccggc agcccggcca
    15181 gtgcgacgcc ctgaatgccg cgcagcgcga tcagcacacc gagcgacggg gcgaacggca
    15241 ccagcatcgc gagcagcgcg gccaccgcga gggaccacat catcagcgtg cgccggccga
    15301 agcgctcgga gaccgcgctc agcgggatca cgccgagcgc caggccgaag gtcgccgccg
    15361 acacggtcca gctcgcctgg tccgggctca ccccgaggtc ggcggagatc gcgggcagca
    15421 gcgcctgcgt ggagtagagg agggcgaagg tggccacgcc ggcggcgaag agggcgaagc
    15481 tcatccggcg gtagccgggg ccgcccggcc gcagcttgcc cgcttcgggg tcgagcgcgg
    15541 cggcggtgga ggagtcaggg gacgactggg gagaggcggc cgcacggtcg gtgacggacg
    15601 ccccggtatc agcgggaggc atgtttcgaa agtaggcctc tgagtttcat gcgtccaatg
    15661 catggaaacg gcataatcga tgctgtggca cataatcaca gctcacaagg gcctctgttg
    15721 caaggtcgca acagaaaaga caccgccggt tcgggtcgcg ccggggtgga cacgggggag
    15781 gtggccgaac tcggcgccga ttcgtgggcg gtgacgctcg ccccgcggct cgcccagttc
    15841 accgccgtcg cccggcacga acacgtcacc cgcgccgcgc aggagctcgg catgccgcag
    15901 ccgacgctca gccgggccat cgtccgactg gaagaggacc tcggcgtcgc cctcttcgcc
    15961 cggcacggcc gcaccctctc cctcaccccg gccggccggg cctttctcgc cgccaccgag
    16021 cgggcgttga cggacctgga gcgggcgacg gagtccgtac gggccgatgt cgatcccgcg
    16081 gccgggaagg tggcgttcgg ctttctgcac accctcgggt cggagaccgt gcccggcctg
    16141 atccgcagct tccgcgccga ccacccgcgc gtccgcttcc aactcgtcca gaactacggc
    16201 gaggccatga tcgagcggct gcgcgccggc gacctcgatc tgtgcctgac ctcgccggtg
    16261 cccgactatc cggacctggt cgcccgccgg ctcgacgagc agaagctgcg cctggtcgtg
    16321 ccggacgacc atccgctggc cgcccgtaag cggatccggc tcgcggaggc ggccggcgag
    16381 ctgttcgtga ccctcgaacc gggctacggg ctgcgccgga tcaccgacgc gctgtgcgcc
    16441 gaggcgggct tcaccccgcg ggtcgcgttc gagggggagg aggccgagac gctgcgcggg
    16501 ctggtcgcgg ccgggctggg cgtggccctg ctccccccgc cggccgtccc ccgccccggc
    16561 gtcgccgagc tcacggtgac ggcaccgcgc gcggtccgcg agatcggcgt cgcctggctc
    16621 gacggccacc cggacacccc accggtggcc gcgttcaaga agttcctgct gagccgacgg
    16681 gggcggttgt tgcccaggtg aggggcgcgg ccctggggag ttgtgggggg tgggctgggg
    16741 tgttcggagc cgcagcggtg ctccggctcc gaccgctcgt cgcgaggcga cgggcccgtc
    16801 gccggggccc accccggccc tcactgtcgc aatgacgccc cgaaccccgc cgccagcggc
    16861 atccgcagcc ccagcggcgg tggtgcggcc aatgcgtcct tcaccggccg cgcgtagccc
    16921 cgggcgaaca gcgagccgag catgaagtcc gttgccaggg ccaggacttc ggcacggtgc
    16981 tgatgcagcg agtggccgtc ggagtgcacc tcgaagcggc agatgtcgcg gttgaccttc
    17041 ttggcacgct cggcgtagcg gtaggagagg tcggggtcgg tgcgttcgtc gttggtgccg
    17101 tggacgagca ggacctggcg gccgatgagc tgtttcaccg gatcgggcgg ctcgctgtcc
    17161 cggtgcgggt cgggcagcca aggggcgatc gccagtacgg agttgacggc cggatggccc
    17221 gcggcgtgca gggcggcgcg ggcgcccatg cccgtaccga cgaggcagac cgggacatcg
    17281 ccgtagcggc ggaccacctc ctccagggcc cagtccgcgt cccgcgccgg atgggccgcg
    17341 gccccgttcc agccgtggca gcggtagcgc acgacatggg ccgtcaggcc ctcaggacgc
    17401 cccgccttcg ccagccggac cgccagcggg cgcaccgcca gtgccgccac cggcgacggg
    17461 cgccgtaccc cggtcggtcc gccgccgggc agtaaaagcg cgaccccgct cacctcccgg
    17521 ccggtgcccc gcctgccgcc cttccaccgg agcgcttcgc gcgccccctc cttgccggcc
    17581 gttcccagcg gttttcccag ccgggcctca cgcaccggca gtgcttgctg agccatgagc
    17641 agaacgatgg cagaaggagg ctcgccggcc accccgcgga cgggtcactg ttaggtatcg
    17701 ttcgatgaga tctacgcgcg taggggctag agtgccgaga tgacgagcga gaccaccacc
    17761 ctgccgacca gtgaacagat ccgccgcgcc cccaaggtgc tgctccacga tcacctcgac
    17821 ggcggcctgc gccccgccac catcgtcgag ctggcccgtg agatcggcta cgagggactg
    17881 cccgaaacgg acccggaaaa gctcggggtc tggttccgcg aggcctgtga ctccggctcg
    17941 ctggagcgct acctggagac cttcgcccac acctgcgccg tcatgcagac ccgcgacgca
    18001 ctggtccggg tggccgccga atgcgccgag gacctggccg ccgacggtgt ggtctacgcc
    18061 gaggtcaggt acgcgcccga gcagcacctg gagcagggcc tgaccctcga agaggtcgtc
    18121 gaggcggtca acgagggctt ccgcgagggc gagcggcggg cccgcgagaa cggccaccgc
    18181 atccgcgtcg gcgcgctgct gaccgccatg cggcacgccg cccgcgccct ggagatcgcc
    18241 gaactcgcca accgctaccg ggacaccggc gtcgccggct tcgacatcgc gggcgccgaa
    18301 gccggctacc cgcccacccg ccacctcgac gcgttcgagt acctcaagcg ggagaacaac
    18361 cacttcacca tccacgccgg tgaggccttc ggtctgccgt cgatctggca ggccctccag
    18421 tggtgcggcg ccgaccgcct cggccacggg gtccggatca tcgacgacat cgaggtcgcc
    18481 gacgacggct cggtcaagct cggccggctc gcctcgtacg tacgggacaa gcgcatcccg
    18541 ctggagatgt gcccgacctc caacctccag accggcgccg ccccctccta cgccgagcac
    18601 cccatcggcc tgctgcgtcg ccttcagttc cggctcacgg tcaacaccga caaccggctg
    18661 atgagccaca ccagcatgac cgaggaattc gagcacctgg tcaagacatt tcgatacacg
    18721 ctcgatgaca tgcagtggtt tacagtcaat gcgatgaaat cagcgttcat tcctttcgat
    18781 gaacgtctgg ccatgatcaa tgacgtcatc aagcccggtt acgcggaact ccgggccgaa
    18841 tggctgttcc gtccggcggc cacaacgccc cctgcgaaca gcacttctga ctctgcgtaa
    18901 gggctcacgc gagcctatag cgcaacggcc ggtggaatgt ccaccggccg ttttttcttt
    18961 cgtcgtggct gtttgcggcg ccggttgccg cctcagtagg ttgatttgcc ggtcaagccc
    19021 ccatcacgag gacgtaattc gatgaagcag ggaaccatca agactctcgg taccgtcgcg
    19081 ctcggtgccg cttttgtcgt caccgccgcg ggcgtcgcca gcgcggcccc gtcggtcgac
    19141 accgccgggg tgctgaagag cctgccggtg aaggacgcca ccaagaccgt ctccgggctc
    19201 acgaagtcca agccggccgg caacgacgtc aagaccaagc tcaactccca gggcaacaag
    19261 ctgctgggcg gcctgccgac cagcgccgtc accaagaccc tccccctggg tggctgatcc
    19321 cgccacgcgg ctcgtcccct agggacacct tctgcgccgt gccccggccg aacgccctcg
    19381 tgcgtacggc cggggcatcg tcatgtgccg acagggaacc gggcggcggg cgccggaccg
    19441 ggccgtgggc caggcggacg ggcagccggc cgggtcacca ggcggcggcg ccggtggcgg
    19501 ccttctcctc cgaggggagg agtatccaca gcgccaggta gaccaggaac tgcgggccgg
    19561 gcagcagaca cgacaccacg aacagcacac gcatcgtctt cggtgtcatg ccgaagcgac
    19621 gggccaggcc cgcgcacact ccggcgatca ttcggttgtt gctggggcgg accagtgcgg
    19681 cggccatgac ggcggctcct ttgcgactcg atggggcgtt tgcccgatgt ctcaaaggta
    19741 ggtccggctg ccggagagaa catcagcctg cggggccagt tcaaccctgg ggatcctcgg
    19801 ggtcgcctcc ccgagatccc cgtaccggcg acgcagccgg cgccgcgccc cggggacgac
    19861 cgccaggtgc gccagggcca cgccgaggga gccgagcagc accgcgtcga tgtccgggac
    19921 ccggccgggt acccctgact ggagcagctc gatggccagc gagatcatcg cgccggcgaa
    19981 cacggtgcgg gtcagcgaca ccagcggcga aacgttcagc cggccggccg agagaggcag
    20041 cagcacgccc agcggcgcca gcagcagcac cgaaccgccc agatgctgta cggcgtccca
    20101 cgacgggccg tacgccagct cggcccggat cgtcgccagc ggttcgagat tcgtggcgga
    20161 cacccagggc accgtgcggg gacgcaacgt cagccaggcg acgatcagca gatgcgccac
    20221 aaggagaaga agtccggtga cgcgcatacg gggaacggcg gtggtgccgg ggccatgacg
    20281 ctgcacacag gccaggacgc gaccagcggt ggctgcggtt ccgcccaatt gagcccgtct
    20341 tggtgcgccg ggtcagtcct cttccgtcaa cgggtcgccc cacccggcgt tctccgctat
    20401 gtcgggattg gccagcacat ccgccgagca gtcgtagcgg tgcgcggtgg catcgcccgg
    20461 tccgccgagc acggccgcgt gctgcttgcc cagcaccggg ctcgcgccgt acgtgcacac
    20521 cagctgcgcc agtgcgaacg acggcaggtc ctccggccgg atgctcagcc gcagcgtgtc
    20581 cgcggcatcg cccgcgcgcg gtgccgtgac cttcaggtcc tgggggagcg cggtgctgaa
    20641 gccggcccgg tcctcgtcgg acgacggctg ccgctggagt tccttcagca gcgcacgggc
    20701 ggccggcagc cgtggatcgg tggtcgccga gcccttgggc agcgacaccg cccgctcgac
    20761 ctgggccagc gccgagccgc acaccaggta gacggtggcc tgggacctgc cgggcgggtt
    20821 cggcgccggc tcgctcgccg gggccttgca gctcacccgc gagggcgcgc cacccgcgtc
    20881 gaccggtacc gacgtgcccc ggatgccgca gcccgcggcg acgagcgtga gcgccgccac
    20941 ggcggcggtg cgccgccccg tccgcctgat cggcgtcatc gctcgtcctc cgtgccctcg
    21001 tcggccgcgc gggccgtgcc gcggtccctg cggtcgccgt ccgtcagcgg tgtggcgtcc
    21061 atcggcagcc gcagcgtgaa gaccgcgccg ccctcgggga ggttggccgc ggtgatctcc
    21121 ccgccgtgga tatgtgcgtt ctccagcgcg atcgacaggc ccagaccgct gccctccgac
    21181 cgcggccggg acgcgctcgc cttgtagaag cggtcgaaga catgcggaag aacttcttcc
    21241 gggatgccgg ggccgtgatc ccgtacgcgg atcaccagct cgccgccccc gg
//
