LOCUS       NZ_CDME01000015        22048 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Kibdelosporangium sp. MJ126-NF4, whole genome shotgun sequence.
ACCESSION   NZ_CDME01000015
VERSION     NZ_CDME01000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium sp. MJ126-NF4
  ORGANISM  Kibdelosporangium sp. MJ126-NF4
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-NOV-2014) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000826545.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:10:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,648
            CDSs (total)                      :: 10,573
            Genes (coding)                    :: 10,470
            CDSs (with protein)               :: 10,470
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 19 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 5 of 103
            Pseudo Genes (multiple problems)  :: 10 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 69611
            Orig. end                         :: 91659
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CDME01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22048
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22048
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22048
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12048](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12048
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            complement(555..1343)
                     /locus_tag="BN1199_RS42650"
     CDS             complement(555..1343)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.4"
                     /locus_tag="BN1199_RS42650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_198151945.1"
                     /transl_table=11
                     /translation="MRTRASDGPSLRLSLDMAQSGPMKVKSAAEQLVDRLITAIALGAL
                     LPGQKLPPEREFAARLNVSRTTLRDALHQLESLGYVSITRGRSGGVRVHSTWGPESGSH
                     IRSMLLPRWQHLTWLFDLTRSLLPMIAGIAAQRRTDEHIGKIWAAVEAYEQAAEDRDVM
                     RMADHTLHSAIAEATGNPYYVSMDSQLRIQLTFGTDSLPYDTDIRQRALDDHRAIAQAI
                     EAGDSDRAAELTLHHFVDLAEKPMLRLRERVEAAGASESG"
     misc_feature    1394..1407
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 22.38"
                     /tool="antismash"
     gene            1526..2098
                     /locus_tag="BN1199_RS42655"
     CDS             1526..2098
                     /EC_number="2.5.1.17"
                     /GO_function="GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028320.1"
                     /locus_tag="BN1199_RS42655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="WP_042195090.1"
                     /transl_table=11
                     /translation="MAVHLTRIYTRVGDDGTTGLGDFSRVPKTDPRLAAYADVDEANAA
                     IGVAVALGDLPAEIADVLRTVQNDLFDVGADLCTPIADGDDRLRITPAYIERLEGWCDG
                     LNERLPKLTSFILPGGTPGAAYLHVARTVTRRAERTTWALIDDDAERTNVLAAKYLNRL
                     SDLLFILCRLANPDGDVLWQPGGAGIE"
     gene            2177..3043
                     /locus_tag="BN1199_RS42660"
     CDS             2177..3043
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944997.1"
                     /locus_tag="BN1199_RS42660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_042196388.1"
                     /transl_table=11
                     /translation="MPTGEPAGSGPTARRMVLGSQLRRLREAKGISREDAGYAIRGSGS
                     KISRVELGRVSFKERDVADLLTLYGVTDQSDRDIFLGLVRESNQPGWWQRYNDLMPHWF
                     QDFVGLEESASRIQTYEVQFIPGLLQTEAYARAVMLRGRPDAPPEEIDRRVNLRMQRQR
                     LLASPQAPRLWAVIEEACIHRQMGGTKVLRQQLEHLLDLTRMSNISLQILPFELGGSAA
                     ETPFTLLRFAEPELPDIVYLEHLCGALYLDKTDEVEVYNKAAHRLVVEAETPEQTRRTI
                     SKVLKSL"
     misc_feature    3144..3159
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            3247..3369
                     /locus_tag="BN1199_RS58695"
     CDS             3247..3369
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS58695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_255356900.1"
                     /transl_table=11
                     /translation="MSYESEHRDRAKLQSISLSATSGYPASTKPAMINALGGQV"
     misc_feature    complement(3382..3395)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.23"
                     /tool="antismash"
     gene            3488..3724
                     /locus_tag="BN1199_RS42665"
     CDS             3488..3724
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944996.1"
                     /locus_tag="BN1199_RS42665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_042195091.1"
                     /transl_table=11
                     /translation="MTAVHNGVSADRLGGVDWRRSRMSGAVGNCVEVATLESGDIAVRN
                     SRFPNGPALIYTRAEMAAFLAGAKDGEFDDVLS"
     gene            3738..4094
                     /locus_tag="BN1199_RS42670"
     CDS             3738..4094
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010315918.1"
                     /locus_tag="BN1199_RS42670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_042195092.1"
                     /transl_table=11
                     /translation="MDDFEAQLRELITRGFSFAHPRDAAGEVAAVVGVRVHNGVVDVVQ
                     IYGEHDADATRIPGDEMDIFFPYKVFWRSSGRSAAVVAELLSLPDPVPGDVPKVNGCWV
                     PARPGRSKWLSASA"
     gene            4292..4882
                     /gene="sigK"
                     /locus_tag="BN1199_RS42675"
     CDS             4292..4882
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene="sigK"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660631.1"
                     /locus_tag="BN1199_RS42675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ECF RNA polymerase sigma factor SigK"
                     /protein_id="WP_042195093.1"
                     /transl_table=11
                     /translation="MRERAQRSREPGGPRPATLDDLLPRVARGDEAAFEQLYRHLSAPI
                     FGLVQRILRDPAQSEEVAQEVFLELWRSATRYSPERGSVLSWAMTIAHRKSVDRVRSAQ
                     ASTDRDTRAARAETARPFDEVTEVVSGRLEREQVRRCLGTLTELQRESVLLAFYQGYTY
                     REVAHLLDSPLGTVKTRLRDGLIRLRDCMGVTA"
     gene            4879..5616
                     /locus_tag="BN1199_RS42680"
     CDS             4879..5616
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021604.4"
                     /locus_tag="BN1199_RS42680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anti-sigma factor domain-containing protein"
                     /protein_id="WP_042195094.1"
                     /transl_table=11
                     /translation="MNNDVHTLTGAYVLDALSEPERRAFEDHMAGCPACHQEVAELRET
                     TARLGTATAAAPPPQLWNKVHAAIGNVRQLPPMSVNEPTPLRSKRRTSRVVVFAAAASV
                     LAAVGLGVGWVVTNNDLQDELAQRQTELAQLQCALSAPDAKLSTGSVQGSGTATAVVSA
                     RQNCMVMMLNNAPKLPSDKSYQVWYGKQDGVTSAGVLADSNGSLAANDLTPAKGATVLA
                     ITIEPAGGSPAPTSEIIAQIPLA"
     gene            complement(5669..6136)
                     /locus_tag="BN1199_RS42685"
     CDS             complement(5669..6136)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640979.1"
                     /locus_tag="BN1199_RS42685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2550 domain-containing protein"
                     /protein_id="WP_042195095.1"
                     /transl_table=11
                     /translation="MEILWLIGALLAVATVTLILLGVRRVRLIRMGGINVALRTHVDNP
                     RGWHLGVARYHGDEFTWYRALSLRNGPNRIIQRDGFEIDDRREPEAQELYGVPNGAVIL
                     RCRAELDPARSKRAFGGPDTVVEIAMSPDALTGFLSWLESAPPGRRLPYAS"
     gene            complement(6162..6530)
                     /locus_tag="BN1199_RS42690"
     CDS             complement(6162..6530)
                     /EC_number="7.1.2.2"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005440503.1"
                     /locus_tag="BN1199_RS42690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="WP_042195096.1"
                     /transl_table=11
                     /translation="MAEISVELVAVERRLWSGKATMVIAQTTEGELGVLPGHEPLLGQL
                     VEGGVVKIRTTDGGTVIAAVYGGFLSITGDGVSILAENAELAEEIDIDQARAQVAAAQD
                     ADERARAEARVRAAGQTV"
     gene            6643..7143
                     /locus_tag="BN1199_RS42695"
     CDS             6643..7143
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685667.1"
                     /locus_tag="BN1199_RS42695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_042195097.1"
                     /transl_table=11
                     /translation="MPDKGEFENFVAGRSGVLLRTAYLLCAGDRAAAEDLLQEVLERMY
                     PKWKRINGEPEAYARAALANASANRWRRRSRRVNETPLTETAHPHMRGPEDQVVERDQV
                     VRALGALPQRMRAVLVLRFYDDLSEMDTAAALGCGVGTVKSQTSRGLTRLRELLGEKHG
                     SQI"
     gene            7140..8465
                     /locus_tag="BN1199_RS42700"
     CDS             7140..8465
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS42700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_042195098.1"
                     /transl_table=11
                     /translation="MNTDELRTALRDATPEMQPRPSLTADVLRGGVRRLRVRRITIAAT
                     AMAVVAAVSVTATAGWQALSEPNEPATNPLMLEPTHGDLAKDSAFIDDVLDAWDDKPTE
                     PSVKVTSKPHVYWAGNTPAGRAAVVMQETDTKDTLRGLVGVDVKTKKLALLILDEPAPR
                     QGQDMGYRFGQEDRVVLVLKQDQPVHVSAKVIYDQNGKATRSWQPMRDVDAMELAELPP
                     GTGPVEARAIKGDPANGLDGDRLIDLYPADEAAVMADKRSPAGMNWGDGTGTDHLMWAR
                     PGQPPAHWDDAGWLGKRWHKGMSETDLLDPVDAGGIYGDSAGWFATTTGPDSTTYLIGE
                     YVTPESGPTRLYAVAILPSGEVDKVYPAGATNRESPLPVLAQLPDKNTKVAVVKGAKLS
                     YRTTKDGPWLEDADEALRVPKEAVEVRVTKPGQAPAIVPVDR"
     gene            complement(8509..9486)
                     /locus_tag="BN1199_RS42705"
     CDS             complement(8509..9486)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672639.1"
                     /locus_tag="BN1199_RS42705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_042195100.1"
                     /transl_table=11
                     /translation="MTFLRRLTGVAATTLLLATGTAAAADVSPLAIRQVASGLNQAWAV
                     DFLPDGTALFTEKDSKKIRKITSDGKVSDVQTIPGVSVTKEAGLLGLAVSPTYATDQLV
                     FVYYTTSSDNRIAKLKLGEAPTPIVTGIPRGSQYHHGGRIKFGPDGYLYAGTGDGQNGA
                     NAQNKNSLGGKVLRVDKNGAAAPGNPFTSRVYSLGHRNVQGLTWVGSQLYISEIGASSQ
                     DELNKITPGGNYGWPECEGPCDNSKYVNPVKSWPTSQATPSGLTYYKGSLYMAALKGGT
                     YKLNTSGSGGKLYTNLGRTRDEVAGPNNVLWVVTPSGIYNADGA"
     misc_feature    complement(9530..9545)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     gene            9792..9890
                     /gene="pqqA"
                     /locus_tag="BN1199_RS42710"
     CDS             9792..9890
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033797.1"
                     /locus_tag="BN1199_RS42710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_042195101.1"
                     /transl_table=11
                     /translation="MIENTEREVWTTPDFVEYETPMEVTAYAARMD"
     misc_feature    9812..9827
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.23"
                     /tool="antismash"
     gene            10001..10681
                     /gene="pqqC"
                     /locus_tag="BN1199_RS42715"
     CDS             10001..10681
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631254.1"
                     /locus_tag="BN1199_RS42715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_042196390.1"
                     /sec_met_domain="TIGR02111 (E-value: 6.2e-83, bitscore:
                     273.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADEFVGALRGLSHRYWGTHPFHVRMHDGSLSEFELRTWAANRW
                     YYQSVLPQKDAAIISNCPVPRIRRDWLARIVYHDGSAEGEGGRERWLRLCEAVGLTREE
                     VLDERHVAPGVRFAVDAYVTFARTRPWVEAIASGLTEMFSGHLMRQRVTDMLSNYSWIA
                     PADLAYFTNRIDAVSGEGQATVDIVVEYCTTRAEQDRAIAALSFKCDVLWSMLDAIERA
                     AAKE"
     gene            10685..10957
                     /gene="pqqD"
                     /locus_tag="BN1199_RS42720"
     CDS             10685..10957
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336984.1"
                     /locus_tag="BN1199_RS42720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_042195102.1"
                     /sec_met_domain="PqqD_RRE (E-value: 7.7e-24, bitscore:
                     79.2, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.5e-11, bitscore: 38.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIDPASTPRLRRGVRLTYDKTRETHVLLFPEGVLVPNATAASV
                     LQLCDGVATVAEITAELGRKYDGVRVEDVRNVLTRLGERRVVQWT"
     aSDomain        10688..10948
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BN1199_RS42720_PqqD_RRE.1"
                     /evalue="2.20E-25"
                     /identifier="RREFam006.1"
                     /label="BN1199_RS42720"
                     /locus_tag="BN1199_RS42720"
                     /protein_end="88"
                     /protein_start="1"
                     /score="79.2"
                     /tool="antismash"
                     /translation="STIDPASTPRLRRGVRLTYDKTRETHVLLFPEGVLVPNATAASVL
                     QLCDGVATVAEITAELGRKYDGVRVEDVRNVLTRLGERRVVQ"
     gene            10948..12048
                     /gene="pqqE"
                     /locus_tag="BN1199_RS42725"
     CDS             10948..12048
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003079635.1"
                     /locus_tag="BN1199_RS42725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_042195103.1"
                     /sec_met_domain="PTHR43273 (E-value: 5.3e-30, bitscore:
                     100.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.4e-22, bitscore: 76.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.5e-06, bitscore: 23.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.5e-12, bitscore: 43.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.2e-12, bitscore:
                     41.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVTTQPPLGMLAELTHRCPLHCPYCSNPIELVTRDNELSTDEWL
                     SIIDQARDLGVLQVHMSGGEPLARPDLPVLVGRAADLGCYVNLVTSGLGLTDDRLADLV
                     DRGLAHVQLSVQGADAEIANRIAGVKAHNHKLVAARAVRRLDMPLTVNVVLHRANHHQV
                     ADLIALAEEMGADRLELANTQYYGWGLRNRSALMPTAQQLAEAEPIVRAAIERLRDTMQ
                     IVYVVADYHEPYPKPCMYGWGSRQLTVAPNGDVLPCPAASSITTLKLDNVRSRSLADIW
                     YSSEAFNAYRGEDWMPDPCRSCARKGLDFGGCRCQAFLLTGDAGATDPVCSKSPDRGLI
                     DTILAGTPAEPPELVMRKNTIKVGPA"
     gene            12045..12920
                     /gene="pqqB"
                     /locus_tag="BN1199_RS42730"
     CDS             12045..12920
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631257.1"
                     /locus_tag="BN1199_RS42730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_042195104.1"
                     /transl_table=11
                     /translation="MKVLLLGTAAGGGFPQWNCACRMCAAGLPARTQDCVAISADGTGW
                     YLVNASPDIRAQILSAPQLAAGPGPRDTPLRGALLTDAELDHALGLTMLREGTDLQVWA
                     PQAVSGALRTDFPVREIVSRYGDWQWHDAAGTFPVGGLSVTAFPVSDKKPKYVRSTADG
                     PWVVAYRISDPAGGSMVYAPCLKTWPDGFDELIEDASCVILDGTFYSPDEMSGATAKGV
                     ASGAQRAMGHIPIAGPDGSLAQIARHPGKRWVYTHLNNTNPILDPDSAQYKEVLAAGAE
                     APPDGTVIEI"
     gene            complement(13037..13786)
                     /locus_tag="BN1199_RS42735"
     CDS             complement(13037..13786)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS42735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_042195105.1"
                     /transl_table=11
                     /translation="MRRHFAVGLLVPVLMVGACSGGGESGGSTPPPGLGAQQKTEDEQP
                     DQARLRVLETGAAGGNFYAYVENQEDREVAAEVEFTGYDAEGKAYKESARTKPDEKYEV
                     FPAKSTIAVALFVVMEKKPDGTEPKFTRTDARLIPKKRSDIPAHQPGKFEAGPVGKQKM
                     AGTHYVEETVVEVTNGYPQQVRSGVIVVMCKDASGKIQNASSTNFSAAPNEKKKVTLAS
                     AGSGSGCTAYPRMSNTTRFGEGEGEGE"
     gene            complement(13935..16067)
                     /locus_tag="BN1199_RS42740"
     CDS             complement(13935..16067)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="BN1199_RS42740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_052479018.1"
                     /transl_table=11
                     /translation="MTQLTDAAARVVSAGRLGLALVGGEAGAGKTALATALRARLETEG
                     WTARWGGNPEDAPSGWTHVLDPVDVEPSSDPAVVRFRRHQAARAQLASHGRLLVVLDDV
                     HWADEETTALLASLVVDPVVAPVLIVATYRTTDAPTTLLGRVARSEPTRVYLGGLAVSD
                     VAAVVRDAVGLDVDATTAAVIHQRSAGNPFFVRELARLLADDSDLSTVPDGVRDVVRYR
                     LFQLPAAVQAVLHTASVVGDTVALDVVGSLDEVEIAVRHGFLVETAAGQFQFSHALVRD
                     TLYQGLTRSRRAHLHREVGRTLERLRPEDVAALAHHFSQASDERAGRYARAAAELAERR
                     FAFSEAARFWRIALACATDVRDRLALTMGLVRALSFSGSLGESRALRASALDLLDSVDD
                     PHLTAQVIASFDVPAIWTTHDDPALAARVVAVTERVLPSVDPATRGRLLATIAMELRSS
                     GGARAVQAAQQAEAVARELDEPALLAFALNARFMQSFSRAGNTRDRLRIGTELVSLAAR
                     HSLLAFEVLGHLILLQSHSALADFAAADVHAEQVARLGDDYQLPGVGVFTQWYRALRAS
                     VAGQDVSALYRSAAAALADGQMPGFDDGMLSFALLCHEIHNGLPVDRDRDFGAFTPWCR
                     PSGEIPESPRDQLFEARTCLHAAQAVAAADVETMRRLYDELLPATGELAGAGSGMLTLG
                     PVDHYLDELARGIQRG"
     gene            complement(<16191..16843)
                     /locus_tag="BN1199_RS58410"
                     /pseudo=""
     CDS             complement(<16191..16843)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="BN1199_RS58410"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGSSVRIGVLGPLLAADATGPIDLKGPRHRAVLARLLVARGRVVP
                     VDMLVADLWEDPPDGAVGAIQTFVAALRKALEPDRPPRTPATLLVTEGPGYALKLAPDA
                     VDAWRFEAALNGSLSALDEALALWRGPAYAEFTDQAWARAEITRLDELRLLAVERRAEA
                     LLGLGRAAEAVPDLQAHVDGQPLRESAWRLLALASTPLAARAMRWSRCAAPGAC"
     gene            16887..17768
                     /locus_tag="BN1199_RS42745"
     CDS             16887..17768
                     /NRPS_PKS="Domain: Abhydrolase_1 (38-147). E-value:
                     9.2e-25. Score: 79.6. Matches aSDomain:
                     nrpspksdomains_BN1199_RS42745_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662564.1"
                     /locus_tag="BN1199_RS42745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_042195106.1"
                     /sec_met_domain="PF00561 (E-value: 4.2e-18, bitscore: 61.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.1e-17, bitscore:
                     58.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPCTVLSSATKGQALINYERVAVADGVALHTAIQGTGSPVVLLHG
                     FPQTHLMWRHVAADLAADHTVITPDLRGYGDSDKPDGGYDKRTMAADIVELARKLGFSQ
                     FALAGHDRGALVAFRAGLDHPETVTRLGILDILPTVDMWDVLRGVNAAVGFHLYLMAQS
                     SGLPEKLISSAPDAFFGFFLDAWSQQPFPQEIRAAYLAASRAAVSSIVADYRASATVDI
                     EQDTVDLEAGNRLVMPVTVMQQDWGAALGFDAEALWRKWAQDLTHITVTSGHFMAEEAP
                     AEVIKALRALLA"
     aSDomain        17001..17327
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1199_RS42745_Abhydrolase_1.1"
                     /evalue="9.20E-25"
                     /label="BN1199_RS42745_Abhydrolase_1.1"
                     /locus_tag="BN1199_RS42745"
                     /protein_end="147"
                     /protein_start="38"
                     /score="79.6"
                     /tool="antismash"
                     /translation="PVVLLHGFPQTHLMWRHVAADLAADHTVITPDLRGYGDSDKPDGG
                     YDKRTMAADIVELARKLGFSQFALAGHDRGALVAFRAGLDHPETVTRLGILDILPTVDM
                     WDVLR"
     gene            complement(18225..21677)
                     /locus_tag="BN1199_RS42750"
     CDS             complement(18225..21677)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024972.4"
                     /locus_tag="BN1199_RS42750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M12 family metallo-peptidase"
                     /protein_id="WP_157529107.1"
                     /transl_table=11
                     /translation="MSLALLPVFGTAAPAASENPWTKVDGNPVAQRSARQADVRTDQFA
                     GVTLDRAAIQSDLSLAPRAALQGKEVLLPTPEGKFERFSLVDAPVMEEKLAAAHPEIKT
                     YSGKGIDDPTATVRADMTPLGFHASVRSQRGQWYVDPYFHGDYARAESLYASYYGHNLR
                     NDAGPLVENEEIEQVLQEALPADAGPIVKLRTYRLALVTDPSYANYFGAANVTAAKVTL
                     VNRVAQIYEDETAIRLVLVNDTDRTNLNTAAEATGPNGPCGAAACYTTSQLAGCSSGLL
                     NRNQIVLGQLIGAGNYDVGHIGLGLDGGGIAGLGVVGGSGKARGCTGLPTPVGDFFAVD
                     YVAHELGHQFAGNHTFNGTQGSCSGANRSPANSYEPGSGSSIMAYAGICGTDNLQPHSD
                     PYWSQRSYTEISTFTSTPRAPINEVQNIGLRDFDGTDSFTLSYNGQASAPIVRGTNYTA
                     AGIKAAIEGIQGWPAGGTVTVSGFGGTVFGDTGFQVTFQGGPVAAVDVPSLGFDGTGTT
                     AVVGETVDGGPQENTGFKAEDTTNHAPVVTTAAQQYTIPLRTPFSLTGSATDADGDKLT
                     YLWEQNDRGASVGTGLVNNVKKDGPLFRQFGTAAIVTAADTLKYYSPGENAVNDNPTRV
                     FPNLEQVAANNTNAESGVCPTPPAGTVPAPIVDCFSEFLPTADWVGFAGDRTLHFRLTA
                     RDYRAGGGGIGSADTALVLAPNTGPFLVTSQGTAGTVYPGGSAQEIKWDVAGTNAAPIN
                     AAEVKISLSTDGGATFPHVLSERTANDGSENLTLPDVATTKARIKVEAVGNVFFDLNNA
                     DFTILGAPKVTPPPTATVQYSDAASFPVTATDTDSPAEGLTALAEGLPGGLSLTQAGSG
                     SWTVAGTATAAPGDYPVTVSVTDPTGVVGKSAFTVKVAPEDATVTYTGDSLVNGGTVQL
                     RATVQDNTDSTPGDILSGTLTFTTGDQTLCTAPLAQLGTGPTDASGSCTAELPAGVHEI
                     TASAGGNYTGKASGQVELTNARNRVVIGDGSVPLTKAYGADNGSRADFTLAAASLNGRP
                     SVASLVTFTSGGRKFQIRSTKVDSFGAGAGAIDLRGRADLVDVTDHWRPKTAATGLTVR
                     LNGKAKEGLAITLTDGSKLLFSTAWTGASTDVTKLARGTLVII"
     misc_feature    21728..21748
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.94"
                     /tool="antismash"
     misc_feature    21882..21895
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.24"
                     /tool="antismash"
ORIGIN
        1 cgcccatact cgggaagtcg agccagatct gggctccgtg caggccttcc gcctcggcga
       61 cgaccgagcc gtgctcgatc tcgctggtcg cacccagctg gcgcaggccg ttctggtgca
      121 tgtccagcgg acgcgacccg atcgcgtcac cgcccggcag cgccacgacg gcgcggcggc
      181 aacggcccac aagtggcccg aggacgcaca ccgacgcgcg cagcttgccc atggacgccg
      241 cgtcgggctt gtggttgagc tcggacgggg tggtgatgac gactgtgccg ccgtcgacgc
      301 tgacctcgca gccgatgctg cgcaggacgt ccgccatgta cggcacgtcg aggatctgcg
      361 gacagttggt cagcgtcgtc gtgccctccg ccagcaccgc cgccgccatc agcttgagca
      421 cactgttctt ggcaccgatg acatcgacct cgccgacgag tctcgcgccg ccgtgaaccc
      481 ggaagtgctc agacacgcac cctcccgaaa gagaaagacc ttggattggc gccaatcgta
      541 cgggcggccc catctcagcc ggattcggac gctcctgccg cctccacgcg ttcccgcagg
      601 cgcaacatcg gcttctcggc gaggtccacg aaatggtgca acgtcaactc cgccgcacgg
      661 tcgctgtcgc ctgcctcgat ggcctgtgcg atggcccggt ggtcgtcgag cgcgcgctgg
      721 cggatgtcgg tgtcgtaggg cagcgagtcg gtgccgaacg tgagctggat ccgcagctgg
      781 gagtccatgc tgacgtagta gggattgccc gtggcctccg cgatggccga gtgcagcgtg
      841 tggtccgcca tccgcatcac gtcacggtcc tcggcggcct gctcgtacgc ctcgaccgcc
      901 gcccagatct tgccgatgtg ctcgtcggtg cgccgttgcg cggcgatccc ggcgatcatc
      961 ggcagcaacg acctggtcag gtcgaacagc caggtcaggt gctgccagcg gggaaggagc
     1021 atgctgcgga tgtgcgaccc ggactccggg ccccacgtgc tgtgcacccg cacgccaccg
     1081 cttcggccac gcgtgatgct gacgtagccg agggattcca actggtgcaa cgcgtcccgc
     1141 aacgtggtgc ggctgacgtt gagccgggcg gcgaactccc gctccggcgg gagcttctgc
     1201 cccggcagca aggcgccgag cgcgatcgcc gtgatcagcc ggtccaccaa ctgctcggcg
     1261 gcggacttga ccttcatcgg cccggattgg gccatgtcca ggctcagtct gagggacggc
     1321 ccgtcgctcg cacgtgttct caaagtcgaa tgctccctgc gcagccgagc atcgaacata
     1381 gcccatcggg tggttgacgc agatcacttt aggggagcgc cggagttaag ggccagcatc
     1441 tggcccgatt cccgggtaac cctcaggaaa ggcgggaagg atcatgggct gaccggcacc
     1501 ggccgcgtcg aataaggttc gggtcatggc tgtgcacctc acgcgtattt acacacgggt
     1561 cggcgacgac ggcacaaccg ggctcggcga cttctcccgt gtcccgaaga ccgacccgcg
     1621 gctcgcggcg tacgcggacg tcgacgaggc caacgcggcc atcggcgtgg cggtcgcgct
     1681 gggcgacctg cccgccgaga tcgcggacgt gctgcgcacg gtgcagaacg acttgttcga
     1741 cgtgggcgcg gacctgtgca ccccgatcgc cgacggcgac gaccggctgc ggatcacccc
     1801 ggcctacatc gaacgcctcg agggctggtg cgacgggctc aacgagcgcc tgccgaagtt
     1861 gacgtccttc atcctgcccg gcggcacgcc cggcgcggcc tacctgcacg tggccaggac
     1921 ggtaacgcga cgggccgagc ggacgacatg ggcgttgatc gacgacgatg ccgagcggac
     1981 gaacgtgctg gccgcgaagt acctgaatcg gctttccgac ctgctgttca ttctctgccg
     2041 gctggccaac ccggacggtg acgtcctgtg gcaaccgggt ggtgcgggaa tcgaatagcg
     2101 gggacacgcg cgctttgtgt tccttttggt cctagagtgt gtggtcgcaa tacgggcagg
     2161 cgaacaggag gtgaccatgc ccacgggtga gcccgcaggg agtggtccca ccgcgcgccg
     2221 gatggttctc ggcagccagc tgcgtcggtt gcgcgaggcc aagggcatct cccgcgagga
     2281 cgccgggtac gcgatcaggg gctccggctc caagatcagc cgggtcgagc tcggtcgcgt
     2341 cagcttcaag gagcgcgatg tcgccgacct gctcacgctc tacggcgtga ccgaccagag
     2401 cgaccgcgac atcttcctcg gcctggtccg cgagtccaac cagcccggct ggtggcagcg
     2461 ctacaacgac ctgatgccgc actggttcca ggacttcgtc ggtctcgagg agtcggcgtc
     2521 ccggatccag acctacgagg tgcagttcat ccccggcctg ctgcagaccg aggcctacgc
     2581 ccgcgcggtg atgctgcgcg gcaggccgga cgccccgccg gaggagatcg accgcagggt
     2641 caacctgcgg atgcagcgcc agcgcctgct cgcctcaccg caggcgccgc ggctgtgggc
     2701 ggtgatcgag gaggcgtgca tccaccgcca gatgggcggc acgaaggtgc tgcgccagca
     2761 gctggagcac ctgctcgacc tgaccaggat gtcgaacatc tcgctgcaga tcctgccgtt
     2821 cgagctgggc ggctcggccg ccgagacgcc gttcacgctg ctgcggttcg ccgagccgga
     2881 gctgccggac atcgtctacc tcgagcacct gtgcggagcg ctctacctgg acaagaccga
     2941 cgaggtcgag gtctacaaca aagccgcaca tcgactggtt gtcgaagcgg agacgccgga
     3001 gcagacgcgg cggacgatct ccaaggtgct caagtcgctc tagcgcatcc gaccattcgg
     3061 gtgtcaccca cccctgtccg tgaccgattc acgcctcgag ctgcccggat ggagtagtcc
     3121 gacccctggg agtccggtat accagttacg ggtgttaacg attcggcatc ctcgcggtga
     3181 acaccaggct cgggcgccgc gccgacatgc tcacggtcat cacaatttcc cccagacgat
     3241 gcttatgtgt cgtacgaatc ggagcaccgc gaccgggcga aactgcaatc gatctcactg
     3301 tcggcgacca gcggctaccc agcgtcgaca aaacctgcca tgatcaacgc cctcggcggc
     3361 caagtgtgaa aatcgtgcag atgcacgtgc atgcgcccgt gcactcgccc gtgctacctt
     3421 gctggtgcac gaagatcgat tgacgtgccg ccgccaaggc aagtcgggga aaaggtggga
     3481 gcactccatg acggcagtac acaacggggt atccgcggat cgactgggag gcgtcgactg
     3541 gcgccgcagc cggatgagcg gagcagtagg aaactgtgtc gaggtcgcga ccctggagtc
     3601 cggcgacatc gcggtgcgca actcgcggtt cccgaacggt ccggcgctga tctacacacg
     3661 ggccgaaatg gcagccttcc tcgccggtgc gaaggacggc gaattcgacg acgttctgtc
     3721 gtgacgaagg tggcgacatg gacgacttcg aagcgcaact cagggagctg atcacccgcg
     3781 ggttcagctt cgcgcatccg cgcgatgccg ccggtgaggt ggccgccgtc gttggcgtgc
     3841 gagtccacaa cggtgtggtc gacgtagttc agatctacgg cgaacacgat gccgacgcca
     3901 cccgcatccc gggtgacgag atggacattt tctttcccta caaggttttc tggcgatcca
     3961 gcggtcgatc cgccgcagtc gtcgcagaat tgctgtccct gcctgatccc gtgcccggtg
     4021 acgtgcccaa ggtcaacgga tgctgggttc cggcccgtcc tggcaggtcg aaatggctgt
     4081 ccgcgtccgc gtgagcccag ccgtgctgcc gcgtgatggc agctcgggtc cccgagcgtt
     4141 catcagagaa ctgggtgtca gacttgccgc aggggtgact cgactgagtc gctcccgcgg
     4201 cgccaaaacg cactaacctt ctcaaccaat ccgcctgcac gtcgggagcg aatcacctgg
     4261 cgtgcaggtt gaggtacgag gaggggtgag catgcgggaa cgggcgcagc gatcacggga
     4321 gcctggcgga ccacgaccgg ccaccctgga cgacctgctg ccccgcgtcg cccgcgggga
     4381 cgaagctgcc ttcgagcagc tctaccgcca cctctccgcc ccgatcttcg ggctggtgca
     4441 gaggatcctg cgggatccgg cccagtcgga ggaggtcgcg caggaagtct tcctcgaact
     4501 ctggcgatcc gccacgcgct acagcccgga acgcggctcg gtgctgtcgt gggccatgac
     4561 gatcgcgcac cgcaagtccg tcgaccgggt ccggtccgcc caggcgagca ccgaccgcga
     4621 cacccgcgcc gcccgcgccg agaccgcgcg tcccttcgac gaggtcaccg aggtcgtctc
     4681 gggcaggctg gaacgcgaac aggtccgccg gtgtctcggc acgctcaccg aactgcaacg
     4741 cgagtcggtc ctgctcgcgt tctatcaggg ctacacctac cgggaagtcg cgcacctgct
     4801 cgactcgcca ctcggaacag tcaaaacacg attgcgggac gggctgatca ggctgcgtga
     4861 ctgcatgggg gtgacggcgt gaacaacgat gtgcacacac tgacgggcgc gtatgtgctt
     4921 gacgcgctgt ccgaaccgga gcgcagagcg ttcgaggacc acatggccgg gtgcccggcc
     4981 tgccaccagg aggtcgcgga actccgcgag accacggccc ggctcggcac cgcgaccgcc
     5041 gccgctccgc cgccgcagct gtggaacaag gtgcacgcgg cgatcggcaa cgtccggcag
     5101 ctgccaccta tgtccgtaaa cgagccgacg ccgttgcgct cgaagcgcag gacgtcccgg
     5161 gtcgtggtgt tcgccgcggc cgccagcgtt ctcgccgcgg tgggtctcgg cgtcggctgg
     5221 gtcgtcacga acaacgacct gcaggacgag ctcgcccagc gtcagaccga gcttgcacag
     5281 ctccagtgcg cgctgagcgc gccggacgcg aagctgagca ccggcagcgt gcagggcagt
     5341 ggcacggcca cagcggtcgt ctcagcgcgt cagaactgca tggtgatgat gctcaacaac
     5401 gccccgaagc tgcccagcga caagagctac caggtctggt acggcaagca ggacggcgtg
     5461 acatcagccg gagttctcgc tgattccaac gggtccctcg cggccaacga cctcacgccc
     5521 gccaaggggg cgacggtgct ggcgatcacg atcgagcccg ctggcgggtc accggctccc
     5581 accagcgaga tcatcgcgca gatccccctg gcctgacctc gtgagtgttt tggccggttc
     5641 taaccggcca aaacactcac gagctctttc aggaggcgta ggggaggcga cgtcctgggg
     5701 gcgctgactc gagccacgac aggaagccgg tcagcgcgtc cgggctcatc gcgatctcga
     5761 ccacggtgtc cgggccgccg aacgcgcgct tggagcgcgc cgggtccagt tctgctcggc
     5821 atcgcaggat gaccgcgccg ttgggcacgc cgtagagctc ctgggcttcc ggttcgcggc
     5881 ggtcgtcgat ctcgaacccg tcgcgctgga tgatccggtt cggcccgtta cgcaggctca
     5941 gcgcgcggta ccaggtgaac tcgtcaccgt ggtagcgggc cacgccgagg tgccagccgc
     6001 gcggattgtc cacatgggta cgcagggcga cgttgatccc gcccatccgg atcagcctga
     6061 ccctgcgcac acccagcaag atcaatgtga cggtcgcgac cgccaggagc gccccgatca
     6121 accagaggat ctccatggcc gcccccgccc agtccctcgg atcagaccgt ctgtccggcg
     6181 gcacgcaccc gggcttcggc tctggcgcgc tcgtccgcgt cctgtgccgc ggctacctgc
     6241 gcccgcgcct ggtcgatgtc gatctcctcg gcgagctcgg cgttctccgc gaggatactc
     6301 acgccgtcac cggtgatcga gaggaaaccg ccgtagaccg cggcgatgac cgtgccgccg
     6361 tccgtggtgc ggatcttgac gacaccaccc tcgaccaact gcccgagcag cggttcgtgg
     6421 ccgggcagca cgccgagctc accctcggtc gtctgcgcga tgaccatcgt cgctttgccc
     6481 gaccacagcc ggcgctcgac agcgacaagt tcaacggaaa tctcggccac gcgtttctcc
     6541 ttcgtgtccc cgtgctccgc aagtctaaac ggcaagggtt cgcaacctcg acgcccctcc
     6601 cggtgtgatg ctggtcgacg acggcattaa gggggttacc gggtgccgga caagggcgag
     6661 ttcgagaact tcgtcgcggg ccgttcgggt gtcctgctgc ggacggcgta cctgctctgc
     6721 gcaggtgacc gtgccgcagc ggaagacctg ctgcaagagg tgctcgaacg gatgtacccg
     6781 aagtggaaac ggatcaacgg cgagccggag gcgtacgcga gagccgcgct ggcgaacgcg
     6841 tcagccaacc ggtggcggcg acggtccagg cgcgtgaatg agacaccgct cacagagaca
     6901 gcgcatccgc acatgagagg tcctgaggac caggtggtcg aacgcgacca ggtcgtgcgc
     6961 gccctcggcg cgctgcccca acgcatgcgc gcggtcctcg tcctgcgctt ctacgacgac
     7021 ttgagcgaga tggacaccgc agccgcgctg ggctgtggcg tcggcacggt gaaaagccag
     7081 acatcgagag gactgacccg gctgcgggag ttgctcggcg agaaacacgg gagccagata
     7141 tgaacaccga cgagctgcgc acggccctgc gcgacgccac tcctgagatg caaccgcgcc
     7201 caagcctcac cgcggacgtg ctgcgcggcg gcgtacgacg actgcgcgtg cgacggatca
     7261 ccattgccgc gacggctatg gccgtggtgg cggcggtctc cgtgacagcg acggctggat
     7321 ggcaggcact gtcggagccg aacgaaccgg ccaccaaccc gctgatgctc gaaccgacgc
     7381 atggcgacct ggcgaaggac agcgcgttca tcgacgacgt gctcgacgcg tgggacgaca
     7441 agcccacgga gccgtccgtg aaggtgacgt cgaagccgca cgtgtactgg gcgggcaaca
     7501 cgcccgctgg ccgtgccgcg gtggtgatgc aggagaccga cacgaaggac accctgcgag
     7561 gcctggtcgg cgtggacgtg aagaccaaga agctggcact gctgatcctg gacgagcccg
     7621 caccacgcca agggcaggac atgggctaca ggttcgggca ggaggatcga gtcgtcctcg
     7681 tgctgaagca ggaccagccg gtgcacgtct ccgcgaaggt catctacgac cagaacggca
     7741 aggcgacccg cagctggcag ccgatgcggg acgtggacgc catggaactg gccgagcttc
     7801 cccccggcac aggcccggta gaggcccggg cgatcaaggg cgacccggcc aacggcctcg
     7861 acggcgacag gctgatcgac ctctaccccg ccgacgaggc cgccgtgatg gcggacaagc
     7921 ggagtcccgc gggcatgaac tggggtgatg gcacgggcac ggaccatttg atgtgggcgc
     7981 gtccaggcca gccaccggca cactgggacg acgccgggtg gctgggcaag cgctggcaca
     8041 agggcatgtc cgaaacggac ctgctcgacc ccgttgacgc cggtggaatc tacggcgaca
     8101 gcgcgggttg gttcgccacg acgactggac cggactcgac gacgtatctg atcggcgagt
     8161 acgtgacgcc cgaaagcgga cccacgcggt tgtacgcggt ggcgatcctc ccgtccggcg
     8221 aggtcgacaa ggtctacccg gcaggcgcga caaaccggga aagcccgctg cccgtgctgg
     8281 cccagttgcc ggacaagaac acgaaggtgg ccgtggtgaa gggcgcgaag ctgagctacc
     8341 ggaccacaaa ggacggtccg tggctcgagg acgccgacga ggcgctgcgc gtcccgaagg
     8401 aagccgtcga ggtcagggtg accaagccgg gccaggcgcc cgcgatcgtc ccggtcgacc
     8461 gctagcccgc gtggcccgcc cgagttcacg cgggcgggcc acgctttctc aggcgccgtc
     8521 ggcgttgtag ataccgctgg gagtgaccac ccagagcacg ttgttcgggc ccgcgacctc
     8581 atcgcgtgtc cggccgaggt tcgtgtacaa cttgccgccc gagccgctgg tgttgagctt
     8641 gtacgtaccg cccttcagcg cggccatgta caggctgccc ttgtagtacg tgagcccgct
     8701 cggcgtcgcc tgggaggtcg gccacgactt gaccgggttg acgtacttcg agttgtcgca
     8761 gggaccttca cattccggcc agccgtagtt gccgccgggc gtgatcttgt tcagctcgtc
     8821 ctggctgctc gcaccgatct ccgagatgta gagctggctg ccgacccagg tcaggccctg
     8881 cacgttgcgg tgccccagtg agtagaccct gctggtgaac gggtttcccg gcgccgccgc
     8941 gccgttcttg tcgacgcgga gcacctttcc gccgagtgag ttcttgttct gcgcgttggc
     9001 gccgttctgg ccgtcgcccg ttcccgcgta gaggtagccg tccgggccga acttgatccg
     9061 gccgccgtgg tggtactgcg agccacgggg aatcccggtc acgatcgggg tcggcgcctc
     9121 tcccagcttg agtttggcga tcctgttgtc ggaacttgtc gtgtaataga cgaacacaag
     9181 ctggtcggtg gcgtacgtcg gggacaccgc gaggccgagc aggcccgcct ccttggtgac
     9241 gctcacgccg gggatcgtct gcacgtcgga gaccttgccg tcggaagtga tcttccggat
     9301 cttcttcgag tccttctcgg tgaacaaagc cgttccgtca ggcaggaagt cgaccgccca
     9361 cgcctggttg agtccactcg cgacctgccg gatggccagc ggcgacacgt ccgcggcggc
     9421 cgcggtgccg gtggcaagca gcaatgtcgt cgcggcgaca ccggtgagcc tgcggagaaa
     9481 tgtcatgggt ttgcctcctg gagcgtcact tggggctact cgggcggcgt gtgaatacaa
     9541 acacagcggg tgtcgatcgt cctacctccg accgggctaa cgaggccgga aacctccgac
     9601 cactgttgtc acagtcggtg acagagctgc gaaaagagtg tcccagtcac agggaccggc
     9661 gtcccgacca gtcagggaaa ccacttagag gactagcctt ctcgcccggt cagctcctac
     9721 gctcgaagtg ctcgacacga atcctcccga cgacgaccca tgccggttcg tcaccgatcc
     9781 gaggagtgca catgatcgaa aacacggagc gcgaggtctg gaccactccg gacttcgtcg
     9841 agtacgaaac gccgatggag gtcacggcct acgcggccag gatggactga gcatcgtcct
     9901 tcgcgcgggg gccgaccggt gagcggcggc cctcgccact cctctcccct gcatggagga
     9961 acccgcagtg tccaccgaac tgtccacttc gtacccaccg atgaccgccg acgagttcgt
    10021 cggcgcactg cgcggtctgt cccaccgcta ctggggaacc cacccgttcc acgtcaggat
    10081 gcacgacggc agcctgtcgg agttcgagtt gcgcacgtgg gcggcgaacc gctggtacta
    10141 ccagagcgtg ttgccgcaga aggacgccgc gatcatcagc aactgcccgg tgccgcggat
    10201 ccgccgcgac tggctggcca ggatcgtcta ccacgacggc tcggctgagg gcgagggcgg
    10261 acgcgaacgg tggctgcggc tgtgcgaggc cgtcggcctg accagggaag aagtcctgga
    10321 cgagcggcat gtcgcgcccg gcgtgcggtt cgcggtcgac gcgtacgtca ccttcgcgcg
    10381 gaccagacca tgggtcgagg cgatcgcctc cggcctgacc gagatgttct ccggccacct
    10441 gatgcgccag cgcgtcaccg acatgctgtc gaactattcg tggatcgccc cggcggacct
    10501 cgcctacttc accaaccgga tcgacgcggt gtccggcgag ggacaggcca cagtggacat
    10561 tgtggtcgag tactgcacga cgcgtgccga gcaggacagg gccatcgccg cgctgtcgtt
    10621 caagtgtgac gtgttgtggt ccatgttgga cgccatcgag cgggcagcag ccaaggagta
    10681 gccgatgagc acgatcgatc cggcctccac gccacggctg cgccggggcg ttcggctcac
    10741 ctacgacaag acccgcgaga cgcacgtcct gctcttcccg gaaggcgttc tcgtgcccaa
    10801 cgcgacggcc gcgtcggtgc tgcaactctg cgacggcgtc gcgacggtcg ccgagatcac
    10861 ggccgagctt ggccgcaagt acgacggagt ccgggtcgag gacgtacgca acgtgctgac
    10921 caggctggga gaacggcggg tcgtgcagtg gacgtgacca cacaaccacc gctgggcatg
    10981 ctcgcggagc tgacccaccg ctgcccgctg cactgcccgt actgctccaa tccgatcgag
    11041 ctggtgacca gggacaacga gctgtcgacg gacgagtggc tctcgatcat cgaccaggca
    11101 cgggacctgg gtgtgctgca ggtgcacatg tccggcggcg agccgttggc acgcccggac
    11161 cttccggttc tcgtgggcag agcggcagac ctcggatgtt atgtcaacct ggtgaccagc
    11221 gggctcggcc tgaccgatga ccggctcgcc gacctcgtcg accgcggtct cgcgcacgtc
    11281 cagctgtcgg tgcagggcgc cgacgccgag atcgccaacc gcatcgcggg cgtgaaagcc
    11341 cacaaccaca agctcgtggc ggcccgcgcg gtgcgcaggc tggacatgcc gctgacggtg
    11401 aacgtggtcc tgcaccgcgc gaaccaccac caggtcgcgg atctgatcgc gctcgccgag
    11461 gagatgggcg cggaccggct ggaactggcc aacacccagt actacggctg ggggctgcgc
    11521 aaccggtcgg cgctgatgcc caccgcgcag caactggccg aggccgagcc gatcgtgcgc
    11581 gcggcaatcg aacgcctgcg tgacacgatg cagatcgtct acgtggtcgc ggactaccac
    11641 gagccgtacc ccaaaccctg tatgtacggc tggggttcgc ggcagctgac agtggcaccg
    11701 aacggtgacg tgctgccctg cccggccgcc tcgtcgatca cgacgctgaa gctggacaac
    11761 gtccggtcgc ggtcgttggc tgacatctgg tactcctcgg aggcgttcaa cgcctaccgc
    11821 ggcgaggact ggatgcccga cccgtgccgc agttgtgcac gcaagggcct cgacttcggc
    11881 ggctgccggt gccaggcgtt cctgctgacc ggcgacgctg gcgcgaccga cccggtctgt
    11941 tcgaagtcac ccgaccgcgg gctgatcgat acgatactgg cgggaactcc ggccgagccg
    12001 ccggaactgg tgatgcggaa gaacacgatc aaggtgggtc cggcgtgaag gtactgctgc
    12061 tgggaacggc cgcgggcggc ggattcccgc agtggaactg cgcctgccgg atgtgcgcgg
    12121 ccggtctgcc cgcccgcacc caggactgcg tggcgatcag tgcggacggc acaggctggt
    12181 acctggtcaa cgcctcgccg gacatccgcg cccagatcct gtccgcgccg caactcgccg
    12241 ccggtcccgg cccgcgtgac actcccctgc gcggagcgct gctgaccgac gcggaactcg
    12301 accacgccct cggtctgacc atgctccgtg aaggcacgga cctgcaagtg tgggcaccgc
    12361 aagccgtttc gggtgcgctg cgcacggact tcccggtacg ggagatcgtt tcccggtacg
    12421 gcgactggca atggcacgac gctgccggga ccttcccggt cggtgggctg tcggtgaccg
    12481 ccttccctgt cagcgacaag aagcccaagt acgtccggtc cacagcggac ggtccgtggg
    12541 tggtggcgta ccggatctcg gatccggcag gcggctcgat ggtctacgcg ccgtgcctga
    12601 agacgtggcc ggacggcttc gacgagctga tcgaggacgc gtcctgcgtg atcctcgacg
    12661 gaacgttcta ctcaccggac gagatgtccg gcgcgacggc caagggcgtg gcatccggcg
    12721 cccagcgcgc gatggggcac atcccgatcg cgggcccgga cggcagtctc gcgcagatcg
    12781 cccgtcaccc gggcaagcgc tgggtctaca cgcacctcaa caacaccaac ccgatcctcg
    12841 accccgattc cgcgcagtac aaggaagtcc tcgccgccgg ggccgaagcc ccgcccgacg
    12901 gcacggtgat cgagatctag cgccggaact cccgcgctcg cgctcgcccc gctcgtcccc
    12961 gtgcaaccaa tgtggccttc ggtgctatca gcgcaacaat ggccaccttc gttgcacgct
    13021 cacccggcag cactggctac tcgccttcgc cttcgccttc gccgaagcgg gtggtgttgg
    13081 acatccgcgg gtaggcggtg cagccgctgc ccgacccggc ggaggccagc gtcaccttct
    13141 tcttctcgtt cggcgctgcg ctgaagttgg tcgacgacgc gttctggatc ttgccggagg
    13201 cgtccttgca catcaccacg atcacaccgc tcctgacctg ctgcggataa ccgttggtca
    13261 cctcgacgac ggtctcttcg acgtagtggg tgcctgccat cttctgcttg ccgaccggac
    13321 ctgcctcgaa cttccctggc tggtgcgcgg ggatgtcgga ccgcttcttc gggatcagcc
    13381 gcgcgtccgt cctggtgaac ttgggctcgg tgccgtccgg tttcttctcc atcaccacga
    13441 acagcgcgac cgcgatcgtg cttttcgccg ggaagacctc gtatttctca tccggtttcg
    13501 tccgcgctga ttccttgtag gccttgcctt cggcgtcata tccggtgaac tcgacctcgg
    13561 cggcgacttc ccggtcctcc tggttctcga cataggcgta gaagttgccc ccggctgcgc
    13621 ctgtttccag tacccgcaac cgcgcctggt ccggctgctc gtcctcggtc ttctgctggg
    13681 cgcccaggcc aggcggcggc gttgacccgc ccgattcgcc cccgccggag caggccccga
    13741 ccatgagaac cggcacaagc agcccgacgg cgaaatggcg tcgcatctga ttccccttga
    13801 tcccgacctg gcaagtgatc aggacggtaa caggaccacc gcgcctttcg cagcagcgaa
    13861 ccgcccactg caagccgacc aaaagaaaac ctcaagatca catcatggcg aatacgcaat
    13921 gcgaaccgac gactttaacc ccgttgaatt ccacgcgcca gttcgtcgag atagtggtcg
    13981 acgggcccga gggtgagcat cccgctgccc gctccggcca gttcgcccgt tgcgggcagc
    14041 agttcgtcgt acagccgtcg catcgtctcg acgtcggcgg cggcgacggc ctgggcggcg
    14101 tgcaggcacg tcctggcctc gaacagctgg tcccgtggtg attccgggat ctcgccggat
    14161 ggcctgcacc acggcgtgaa cgcgccgaag tccctgtccc ggtcgacagg aagtccattg
    14221 tggatctcgt ggcacagcag ggcgaacgac agcatcccgt cgtcgaatcc cggcatctgg
    14281 ccatcggcga gcgcggcggc cgcggaccgg tacagcgccg acacgtcctg cccggcgacc
    14341 gaagcgcgaa gcgcccggta ccactgtgtg aagacgccaa cgcccggtag ctggtagtcg
    14401 tcgcccagcc gagccacctg ctcggcgtgc acgtcggcgg cggcgaagtc ggcgagggcg
    14461 gagtgcgact gcagcagaat caggtgtccg agaacctcga aggccagcaa tgagtgccgc
    14521 gcggccagcg agaccagttc cgtcccgatc cgcagccggt cccgggtgtt gcccgcgcgg
    14581 gagaacgact gcatgaaccg cgcgttcagc gcgaacgcca gcagcgcggg ctcgtccagc
    14641 tcacgcgcga cggcctcggc ctgctgcgcg gcctgcaccg cacgggcccc gcccgagctg
    14701 cgcagttcca tggcgatcgt ggccagcagc ctgccgcggg tcgctgggtc gactgacggg
    14761 agtacgcgtt cggtgaccgc caccacccgt gccgccagtg cgggatcgtc gtgcgtggtc
    14821 cagatcgccg ggacgtcgaa cgaggcgatc acctgggctg tcaggtgcgg atcgtcgacc
    14881 gagtcgagca ggtcgagcgc ggaggcccgc aacgcccgcg actcgccgag ggatccgctg
    14941 aacgacaacg ccctgaccag gcccatggtc agggccaggc ggtcacggac gtccgtcgcg
    15001 caggccagtg cgatccgcca gaaccgggcc gcctcactga aggcgaaccg ccgctcggcc
    15061 agctcggccg cggcccgcgc gtaccgaccg gctcgttcgt cggaagcctg cgagaagtgg
    15121 tgtgccagcg cggcgacgtc ctcgggccgt agccgttcca gtgtccggcc gacctcacga
    15181 tgcagatgcg cccgccgtga ccgggtaagg ccttggtaca gggtgtccct gaccaacgcg
    15241 tgcgagaact ggaactgccc tgccgcggtt tcgacgagaa agccgtgccg caccgcgatc
    15301 tcgacctcgt cgagcgaacc gacgacatcc agtgcgacgg tgtcaccgac gacagaagcc
    15361 gtgtgcagaa ccgcttgcac cgcagcaggc aattggaaca ggcgataccg cacgacgtca
    15421 cgcaccccgt cgggcacagt ggacagatcg ctgtcgtccg cgagcagccg ggccagttcg
    15481 cggacgaaga acgggttccc ggcgctgcgc tggtggatca ccgccgcggt cgtcgcgtcc
    15541 acgtccagcc ccacggcgtc acgcaccaca gctgcgacat ccgacacggc cagccccccg
    15601 agatagacac gggtcggttc ggagcgggca acacggccga gcaacgtcgt cggcgcgtcc
    15661 gtcgtgcggt aggtcgccac gatcagcacc ggcgccacga ccgggtcgac gaccagggaa
    15721 gccagcagcg ccgttgtctc ctcgtcggcc cagtgcacgt cgtcgagaac cacgagcaag
    15781 cgtccgtgcg acgccagctg cgcgcgggcg gcttggtggc gacggaaccg gacgacggcc
    15841 ggatcgctgg acggctcgac gtcgacgggg tcgagaacat gtgtccagcc ggacggagca
    15901 tcctcgggat tgccgcccca ccgggcagtc cagccttccg tttccagccg ggcgcgcaag
    15961 gccgtggcca gcgcggtctt cccggctccc gcctccccgc cgaccagtgc caggcccagc
    16021 ctgcccgcac tgaccacccg ggcggcggca tcggtcagct gcgtcatctc ctcgtcccgt
    16081 ccgaccagta gaggggccga gggagccgga atgagccgtg gggcgtgtgc caggacgtcg
    16141 gattccagtt gccgcagcgc gggaccggga tcgacgccga gctcgtccgc cagcaggcgc
    16201 cgggcgcggc gcaacgactc cagcgcatcg ccctggcggc cagcggtgta ctggccaacg
    16261 ccagcagccg ccaggcgctc tcacgcaacg gctgtccgtc cacatgcgcc tgaagatccg
    16321 gaacggcctc agcggcacgc cccagcccca gcagcgcctc ggcgcgccgt tcgactgcga
    16381 gcagccggag ctcgtccagc cgcgtgatct ccgcccgtgc ccacgcctgg tcggtgaact
    16441 cggcgtacgc gggcccgcgc cacaacgcga gcgcttcgtc caatgcggac agcgaaccgt
    16501 tcagcgcggc ctcgaaccgc cacgcgtcga ccgcgtccgg ggccagcttg agcgcgtagc
    16561 ccggtccttc ggtcaccagg agcgtcgctg gcgttcgcgg cggccggtcc ggctccagcg
    16621 ccttgcgcaa cgcggccacg aaggtctgga tcgcgccgac cgcgccgtcc ggtgggtcct
    16681 cccagaggtc tgcgacgagc atgtcgaccg gcacgacccg gccgcgcgcg acgagcaggc
    16741 gggccagcac ggctcggtgc ctcggtcctt tgaggtcgat cgggccggtg gcgtctgcgg
    16801 ccagcagcgg acccagcacg ccgatccgca cagaggaacc catcgccggt cactgtactc
    16861 agccaacgct gacccgttgc tgattgatgc cctgcacagt gctctcatca gcaacgaagg
    16921 gacaagcctt gatcaactac gagcgggtgg ccgtcgccga cggcgtggcg ctgcacacag
    16981 cgatccaggg caccggcagc ccagtcgtgc tgctgcacgg cttcccacaa acccacctga
    17041 tgtggcggca cgtggccgcc gacttggccg ctgaccatac tgtcatcact cctgacctgc
    17101 gtggatacgg cgacagcgac aaaccagacg gtgggtacga caagcggacc atggcggcgg
    17161 acatcgttga actcgcccgc aagctgggct tctcgcagtt cgcgctggcc gggcacgacc
    17221 gtggcgctct ggtggcgttc cgcgccgggc tcgaccatcc ggagaccgtc acccgattgg
    17281 gcattctcga catcctgccc acagtggaca tgtgggatgt gctgcgcggt gtcaacgcgg
    17341 ctgtcggttt tcacctgtat ctgatggctc agtcgtctgg cctgccggag aagctgatct
    17401 cctcggcacc ggacgcgttt ttcggcttct tcctggacgc ttggtctcag cagccgttcc
    17461 cccaggaaat tcgtgccgct tacctggccg cgtcgcgagc cgccgtatca tctatcgtcg
    17521 ccgactatcg tgccagcgcc actgtggaca tcgagcagga caccgtggac ctggaagcag
    17581 gcaaccggct cgtgatgccg gtgaccgtga tgcagcagga ctggggcgcc gcgctcggct
    17641 tcgatgccga agccctgtgg cggaagtggg cacaggacct tactcacatc acggtcacgt
    17701 ccgggcattt catggccgaa gaggcaccgg ccgaggtgat caaggcgttg cgggccttgt
    17761 tggcatgagc gctgcagccg aaggcccgcc tcagggatgt gattttgatg cctggcgcgt
    17821 cgggctcgtt cctcacgctc gagttcgctc gtggcctgaa ctgcatgtcc tcgccggacg
    17881 gcaggcctcc gagagggaca ccacagacct cttcgtttct cgcgcccgtt cgcttagccc
    17941 acgtgatttc ctgggtcgag tggggggcgc ggggcgcccc tcccgtacgg cctgccaaag
    18001 gaaaccacga cgcgccggga gatcggtacc gcctgcgctt cgggttgggt cgcgtaggcc
    18061 gacctcccga cacgccgtgg tatggctacg cccaggccat acgggaggga caccccacga
    18121 accacacccc tgcgcattcg cgcgcgcacg ccgcacgccg gtatgcacaa ggggtggcct
    18181 tcgctttcgc tcaggccacc cctgcacttg ttccttttct ggcgtcagat tatgaccagg
    18241 gttcctctgg ccagcttggt tacgtcagtt gacgcgccgg tccatgctgt ggagaacagc
    18301 agcttcgagc cgtctgtcag tgttattgcc aggccttcct tggcttttcc gttcagtcgc
    18361 acggtcaggc cggtggccgc ggtcttcggg cgccagtggt cggtcacgtc gacgaggtcg
    18421 gcgcggccgc gcaggtcgat cgcgcctgct ccggcgccga acgagtccac ttttgtgctg
    18481 cggatctgga acttcctgcc acccgatgtg aatgtcacca ggctcgctac ggatgggcgt
    18541 ccgttgaggc ttgccgccgc cagtgtgaag tctgctcgtg atccgttgtc tgcgccgtag
    18601 gccttggtca gtggcactga gccgtcaccg attactactc ggttgcgcgc gttggtgagt
    18661 tcaacttgtc cggatgcttt tcccgtgtag ttgccaccgg ccgacgccgt tatctcgtgt
    18721 acacccgctg ggagttctgc tgtgcagcta cccgatgcgt cggttgggcc ggtgcccagc
    18781 tgggccaggg gggctgtgca gagcgtctgg tctcctgtgg tgaatgtcag tgttccgctc
    18841 aggatgtcac cgggagtcga gtcggtgttg tcctgcacgg tggccctcag ttgtactgtt
    18901 ccgccgttta ccagggagtc tccggtgtag gtcaccgttg cgtcctctgg ggccaccttg
    18961 actgtgaacg cggacttgcc gaccacgccg gtcgggtccg tcaccgacac tgtcactggg
    19021 tagtcgcctg gggcggctgt tgccgtgcct gccacggtcc atgagccgga acctgcctgg
    19081 gtcagcgaaa ggcctcctgg caggccttcg gctagtgcgg tcaggccttc ggctgggctg
    19141 tccgtgtcag tggcggtcac tgggaacgag gccgcgtcgc tgtactgcac ggtcgcggtg
    19201 ggcggtggag tcaccttcgg tgcgcccagg atggtgaagt ccgcgttgtt caggtcgaag
    19261 aagacgttgc cgactgcttc gaccttgatc cgtgccttgg tggttgccac gtccggcagc
    19321 gtcaggttct cgctgccgtc gttggctgtg cgctcggaca gcacgtgcgg gaaggttgcg
    19381 ccgccgtctg tggacagcga gatcttcact tctgctgcgt tgatcggcgc cgcgttcgtg
    19441 cctgccacgt cccacttgat ctcctgcgcg gagccgcctg ggtagaccgt tccggcggtg
    19501 ccctgcgagg tcaccaggaa tggaccggtg ttcggcgcga gtaccagtgc ggtgtctgcg
    19561 ctgccgatac cgccgccgcc cgcgcggtag tcccgtgcgg tcaggcggaa gtggagcgtc
    19621 cggtcgcctg cgaagccgac ccagtctgcc gtgggcagga actccgagaa gcagtcgacg
    19681 atcggggcgg ggaccgttcc cgccgggggc gtcgggcaca caccggactc ggcgttggtg
    19741 ttgttcgccg ccacctgttc caggttcggg aagacgcgcg tcgggttgtc gttcaccgcg
    19801 ttctcgcccg gcgagtagta cttcagcgtg tccgctgccg tcacgatcgc ggcggtgccg
    19861 aactgccgga acagcgggcc gtccttcttg acgttgttca ccaggccggt tcccacgctg
    19921 gcgccccggt cgttctgctc ccacaggtag gtgagtttgt cgccgtcggc gtcagtcgcg
    19981 ctgccggtca gcgagaacgg cgtgcgcagc gggatcgtgt actgctgggc cgcggtggtc
    20041 acgaccgggg cgtgattggt ggtgtcctcc gccttgaagc cggtgttctc ctgcgggccg
    20101 ccgtcgacgg tctcgccgac cacggctgtg gtgccggttc cgtcgaagcc cagtgacggc
    20161 acgtccactg ctgcgactgg tccaccttgg aacgtcactt ggaagcctgt gtcgccgaac
    20221 actgtgccac cgaagcctga aacggtcacg gtcccaccgg cgggccagcc ctggattcct
    20281 tcgatcgccg ccttgatccc ggcagccgtg tagttggtgc cccgcacgat cggcgccgac
    20341 gcctgaccgt tgtaggacaa ggtgaacgag tcggtgccgt cgaagtcacg cagaccgatg
    20401 ttctgcacct cgttgatcgg cgcacgcggc gtcgacgtga aggtgctgat ctcggtgtag
    20461 ctgcgctgcg accagtacgg gtcgctgtgc ggctgcaggt tgtccgtgcc gcagatgccc
    20521 gcgtaggcca tgatcgacga gccactgccc ggctcgtagg agttggccgg gctacggttc
    20581 gcgcctgagc aggagccctg cgtgccgttg aacgtgtggt taccggcgaa ctggtggccg
    20641 agttcgtgtg ccacgtagtc caccgcgaag aagtcaccga ccggcgtcgg caaaccggtg
    20701 cagccacgtg ccttcccgct gccaccgacg acaccgagac cggcgatacc gccgccgtcg
    20761 agcccgaggc cgatgtgccc gacgtcgtag ttgcccgcac cgatcagctg cccgagcacg
    20821 atctggttgc ggttcaacag gccgctggag catccggcca gttgcgaggt cgtgtagcac
    20881 gccgccgctc cgcacggacc gttcggaccg gtcgcctcgg cggcggtgtt caggtttgtc
    20941 ctgtcggtgt cgttgaccaa caccagtcgg atcgcggtct cgtcctcgta gatctgcgcg
    21001 acccggttga ccagcgtcac cttcgccgcg gtcacgttcg ccgcgccgaa gtagttcgcg
    21061 taggagggat ccgtgaccag cgccagccgg taagtccgca gcttcacgat cgggccagcg
    21121 tccgcaggca gagcctcctg caggacctgc tcgatctcct cgttctccac cagcggtccc
    21181 gcgtcattgc gcaggttgtg cccgtagtag ctggcgtaga ggctctcggc cctggcgtag
    21241 tcgccgtgga agtacgggtc gacgtaccac tgaccgcgct gtgaacgcac cgaagcgtgg
    21301 aaccccagtg gtgtcatgtc ggcgcggacg gtcgcggtcg ggtcgtcgat tcccttgccg
    21361 gagtaggtct tgatctccgg gtgggccgcg gcgagcttct cctccatcac tggcgcgtcc
    21421 accagcgaga accgctcgaa cttgccctcg ggtgtcggca gcaggacttc cttgccctgc
    21481 agggccgccc gtggcgcgag cgaaaggtcg gactggatcg cggcacggtc cagtgtgacc
    21541 ccggcgaact ggtccgttct gacatcggcc tgtctggccg atctttgcgc gaccgggttg
    21601 ccgtcgacct tcgtccacgg attctccgac gcggccggtg cggccgtgcc gaacaccggc
    21661 agcagcgcca gtgacatacc cgcgatcgcg agcgcggcca cacttcggcc gcgcgttggt
    21721 aatgaggatc tcgccaaagt gacttttctc cttgaaagac ctcgtgagtg gttggtccgc
    21781 ttctaaccgg accaaccact cacgaggaaa tggctatgcg atcaggacac cgccggtctt
    21841 caacgggatc tcctgtgttt tcgcgcccgt ccactcggac gagaacaaca gtttttcgcc
    21901 ctgcaggatg gtgaccgcga cgtcgcggcc ggtctgcgtc accctcagtt cgacgttggc
    21961 cgcgacgaat gtcgcctggc cgttgctgat ttcactgagc aggaccttgg cacgcaggtc
    22021 cagcgaaccg gacgtcttcg ccccgaag
//
