LOCUS       NZ_CDME01000011        21095 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Kibdelosporangium sp. MJ126-NF4, whole genome shotgun sequence.
ACCESSION   NZ_CDME01000011
VERSION     NZ_CDME01000011.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium sp. MJ126-NF4
  ORGANISM  Kibdelosporangium sp. MJ126-NF4
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-NOV-2014) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000826545.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:10:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,648
            CDSs (total)                      :: 10,573
            Genes (coding)                    :: 10,470
            CDSs (with protein)               :: 10,470
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 19 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 5 of 103
            Pseudo Genes (multiple problems)  :: 10 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1887693
            Orig. end                         :: 1908788
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CDME01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21095
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21095
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21095
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11095](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11095)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(913..1587)
                     /locus_tag="BN1199_RS36995"
     CDS             complement(913..1587)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097883.1"
                     /locus_tag="BN1199_RS36995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_042192065.1"
                     /transl_table=11
                     /translation="MAVTDDAILRVREMIMSGELKPGDRLPREADLADRLGLSRNSLRE
                     AVRALSLVRVLDVRQGDGTYVSSLRAGELLGALSFVLDLHRSEESVLEMLEVRRILEPA
                     ATATAALSVSEEDIEELRKLCDATEQAGSVEELVEHDLQFHRRIVTAAGNSYLAQLMDT
                     LAGPTVRVRIWRGISQGGAVDRTVAEHRAIVAALEARQPELARSWATVHVAGVEQWLRD
                     LG"
     gene            1672..2640
                     /locus_tag="BN1199_RS37000"
     CDS             1672..2640
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632686.1"
                     /locus_tag="BN1199_RS37000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_042192066.1"
                     /transl_table=11
                     /translation="MRLGVFLLAGRFPGQDDRDALRRAGDAVGWAEQAGFDDVWIAEHH
                     FMSYGVCPSAITFAAHALGRTERITVGTAVSVLSTTHPVMLAEQVTMLDQMSGGRLHLG
                     VGRGGPWRDLEVFGAGLDRWENGFAESLDLLVECLTEPSVAGTGRFEFRAVPMVPQPVR
                     RPRLTVACTSPGTVAIAAERDLPMLLGMDLDDRGKAAMVDAYTAAGGRASGHIGAALAH
                     VADSRAQAEAELRAAMPSWLGPGLKGYVTVDDRPRKPHDPAGYTEHLIRISPVGTAEDC
                     LEHLRRGTSGVEHHILMVDACGDPQTTRRTIERLGEARSPS"
     gene            complement(2686..4623)
                     /locus_tag="BN1199_RS37005"
     CDS             complement(2686..4623)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005455780.1"
                     /locus_tag="BN1199_RS37005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="WP_042192068.1"
                     /sec_met_domain="APH (E-value: 1.8e-06, bitscore: 24.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWYVLFSLVGVLVLVLSAWVLVVGARKVLGVRVGTIRAVLAAFAA
                     WSTAGFIGGQMPTVFESGSEEIALLFIIPVFGGVLLVAVAILFVLEVMKPTGTGIWFVG
                     GLRSLPGRISRARRYSRITRIALRHGLGPALRGRLRTSDPVKRSQVARSLRQALEEAGV
                     TFVKLGQVLSTRADLLPPEFVEELSRLQDQVSPAPREEIDTVLRDELGDPDGVFAEIDT
                     APLASASVAQVYRAQLTDGTDVVVKVQRPGIRSIVERDLDIMYRLAQTLEERTQWARRL
                     GVLALADGFAKALLEELDFRGEAKNIQAVAADADVKVPVVHRATTRVLIMSRLAGTPLG
                     SAGALIDARGLDRTELARSLLHCLLRQVMRNGVFHADPHPGNVMLLDDGTLGLLDFGSV
                     GRLDGSLRTGLQNLLLAIDRGDPAALRDGLLEVVSRPDDIDEQKLERALGQFIARHFTG
                     GAAPDVEMFTDLFRLVTRYGLSVPPEIAAVFRALATMEGTLAGLAPGFNIVVESRAYAS
                     VRLSEQMDPASLRKTVTEELLTLLPVLRRLPRRIDRIGGALEEGRLSVNVRLFADERDR
                     QLLNGIVHQLMLAFIGATTGIMAVLLLGTTGGPRLVEDITLYQVIGYNLLVISILIGLR
                     LLFAAFRDQR"
     gene            4723..5970
                     /locus_tag="BN1199_RS37010"
     CDS             4723..5970
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672748.1"
                     /locus_tag="BN1199_RS37010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_232328312.1"
                     /transl_table=11
                     /translation="MVGVIRAIFGPVGWKLTYRRWTYLVLGAALIVPFAFAGVAIVPPV
                     LRLLLPADTAEQPLVVAVTMALAIVVWAAGTSFIPAVRVVEGTAARELLGSGVPIQASM
                     RATNLEARWKTCQWFLVHIVVGAVIGALTLFVPIGLLQSFVAPFTGEWLVIQDSPVRVP
                     AGWQSAWIPAVAVVMTVLLVHLVNLAGVGMTKLSQVLLGPTPADHLAELKQRAEQLAER
                     NRLARELHDSVGHALSVVTIQASAAGRVLDTDPKFAQRALSAIEESARAALADLDHVLG
                     LLREDKPGTQPQHTLADLDHLLGTIRLAGVTVETTITGDVPGLPFAVSTEAYRIVQECL
                     TNALKHAGKVTVTLGVAAGHDALEVVAANPLTGHPSPPRGGRGIAGMRERATVLRGQIE
                     AGPDAGTWRVRARIPL"
     gene            6009..6659
                     /locus_tag="BN1199_RS37015"
     CDS             6009..6659
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013224709.1"
                     /locus_tag="BN1199_RS37015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_042192072.1"
                     /transl_table=11
                     /translation="MTVKVLLVDDEELIRAGLRAIIDAEPDLGVVGEAEDGADVLPLVT
                     RLAPDVVLMDVRMPAVDGIQATRHILDRVPNPPKIIVVTTFENDDYVYDALHAGANGFL
                     LKRARPAEIVRAVKVVVAGDSLLFPDKIRALAKRRGLEPGRSGLREAGLTDREAEVLRL
                     MATGLSNVEISDRLFVSVQTVKTHVGNVLSKLHARDRTQAVITAYESGFVTPG"
     gene            complement(6663..8102)
                     /locus_tag="BN1199_RS37020"
     CDS             complement(6663..8102)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (157-470). E-value:
                     2.9e-30. Score: 97.5. Matches aSDomain:
                     nrpspksdomains_BN1199_RS37020_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153740.1"
                     /locus_tag="BN1199_RS37020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_042192075.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.8e-29, bitscore:
                     97.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRLTDGSDLVEVLGDWTSTSAGRAPLYRRLAEAVRRAIHAGDLH
                     AGERLPSERDLARALAVSRATVVSAYDELRSIGLVDSRRGSGTRVVRPPGFRPSVEGRV
                     FGRATPIINRTNEGPGEIISLARAYDPGAPHLRGALLDLVHADLPALLNGSGYHPAGLP
                     ELRSAVAAHLTAAGLPTEPKQVVITTGAQQAIGLITQMYLRRGWTAVVETPSWPGCLDV
                     LRATGVRLVGVELDNEGIRADILSRVMAEHQPDLLYVMPTYHNPTGVMMSTSRRRRVVE
                     LAARYAVPVVEDYAYTVGASDGAPPPIAAFAGSNAEVITIGSLAKSVWAGLRIGWVRAS
                     VETAERLARHKALADLGSPVLDQALAARLLPQLPELAATRIAQLRERLGRARELLTQHL
                     PEWRWRTPDGGSALWIELPNTDARIFAQTALRHGVEVVPGAATDPSGAHDNFIRFPFGF
                     PDDILTELVNRLSKAWAEVRR"
     aSDomain        complement(6693..7631)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1199_RS37020_Aminotran_1_2.1"
                     /evalue="2.90E-30"
                     /label="BN1199_RS37020_Aminotran_1_2.1"
                     /locus_tag="BN1199_RS37020"
                     /protein_end="470"
                     /protein_start="157"
                     /score="97.5"
                     /tool="antismash"
                     /translation="HPAGLPELRSAVAAHLTAAGLPTEPKQVVITTGAQQAIGLITQMY
                     LRRGWTAVVETPSWPGCLDVLRATGVRLVGVELDNEGIRADILSRVMAEHQPDLLYVMP
                     TYHNPTGVMMSTSRRRRVVELAARYAVPVVEDYAYTVGASDGAPPPIAAFAGSNAEVIT
                     IGSLAKSVWAGLRIGWVRASVETAERLARHKALADLGSPVLDQALAARLLPQLPELAAT
                     RIAQLRERLGRARELLTQHLPEWRWRTPDGGSALWIELPNTDARIFAQTALRHGVEVVP
                     GAATDPSGAHDNFIRFPFGFPDDILTELVNRL"
     gene            complement(8276..9967)
                     /locus_tag="BN1199_RS37025"
     CDS             complement(8276..9967)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672750.1"
                     /locus_tag="BN1199_RS37025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EAL domain-containing protein"
                     /protein_id="WP_042192078.1"
                     /transl_table=11
                     /translation="MCAVSATQEMNFAFQPLLSTRTGRVIAVEALPVPSSGTIHSLFKA
                     AGRAGQLTRTDIALAGHALLAAERQDPAIPLHVNILASTAARTDELLHHLLPVLRHSNR
                     HSSDVVFEIGTPFCQARRADLLEGIAKLRAEGFRIALDGIGDGDVPLALIAEAAPNMIK
                     VQSKLLATPDDAATTAMLDALVRLASRTDSRLAAVNVTNDNQLATLSRLGVRVAQGEYL
                     ADSIVDPSRIRTLAEAAGRRVTAVKPPKVTDFLHPALMLPVTATAEEVRATLAERPDIN
                     GIVLVDETWRPQWSIDRSRFLLIVAGPYGHALHAKREASRHADRPLLIDREATGMELLE
                     LVGDTDWERTGDDVAVTDEGGRCVGVVRASDVIRGVADMKVEQAVSLNPLTRLPGTDSV
                     AREVDRRIADNEMFVIAWLDVDAFKTVNDTMGFAAGDDLIRTFGRRITEASASMPNVLV
                     GHVGGDDFLLVTDLDEISALAGVLLDTEWYAEGTPVTVSLASLVCGANTVGSYRDASAM
                     LAPLKKQAKAVPGSSWVLGRPGTDRVDVLRGRPARGPQPQARQPVA"
     gene            complement(10001..11095)
                     /locus_tag="BN1199_RS37030"
     CDS             complement(10001..11095)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803851.1"
                     /locus_tag="BN1199_RS37030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_042192080.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 5.9e-53, bitscore:
                     177.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDVMIAGAGPSGWALAAHCARLGLETTIVAPQPLRRWPATYGLW
                     GDELALLPPDVTAAEPRVVRAYTTKPHVVARHYAILDNDRLMAALSKNVTVVSGRVVTA
                     TATSLELADGRVLTAKTVVNAMGSRGGTAEQTAYGVIVDEQTAAPVVAPGEAIFMDWRS
                     DHNTFLYAMPLGGGKVLLEETALARRPAMDFRALRQALRERLDPYGIKIDTADVERVRF
                     PIDTPRPKRGPVLPFGAAAGFVHPAAGYSVGEAFRLAPMIAAVIAAGEDPWPALWTRRA
                     RLVHFLRHCGLETLLSLSAAESLRFFELFFDLPPDAQRGYLSGRDDPGATMAAMLRIFR
                     KASGRTRVVCAKSVIARVRHMNNR"
     misc_feature    complement(10169..10171)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11157..12710
                     /locus_tag="BN1199_RS37035"
     CDS             11157..12710
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019814812.1"
                     /locus_tag="BN1199_RS37035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="deoxyguanosinetriphosphate triphosphohydrolase
                     family protein"
                     /protein_id="WP_042192082.1"
                     /transl_table=11
                     /translation="MSDPREERRSHGAPAAAFDLATSPFRVDRDRVAGSPFFARLGGVT
                     QVVSASGSGLLHNRLTHSVKVAQVARAIAERLGAAPQYVAIIDSLGGCDPDVAEAAALA
                     HDLGHPPFGHLGEQVLDRLARHRFGLADGFEGNAQSFRIVTTTDVGGPAVVGLDLTAAV
                     RAAMLKYPWTRLHHPEPHPRFMPEPPRGASEPSEGPGTGSGKFSAYVTELDDLEQARAP
                     YEGRLADWQQTVEASVMDTADDIAYAIHDITDFHRIGVLQHAPVAAELGQWQANSATLS
                     WLSDEEVRRQERMPGRSLELLRRRLHEKDSWIVSDEAFHVAVARVRSELVDELLSTPFD
                     GSVEAEQAVARFSLRWTSRLVEEMSVVQAPPTRSGHVMLAREQWHEVQVLKFVHRRFVL
                     LRPDLALHQRGQARLVTKLVEALDQWLGDRFEADRLPRRLHDLVELATSEYGALARSEP
                     GVLVGATGEAPQGRDAIHGLARGRAVIDFVASLTDRQAVSLMDALSGHSGQPWSDAFVL
                     "
     gene            complement(12741..13700)
                     /locus_tag="BN1199_RS37040"
     CDS             complement(12741..13700)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS37040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157528782.1"
                     /transl_table=11
                     /translation="MLALVAAGTFPLPATAAAPEQPPCADFVLGKGDALHPEGIAHDPT
                     RNQFLIGSVTHGTVSTVRPDGSAHTLVNDPKLLTTMGLTVDERRGRLLAVNGDIGIADG
                     STPETNGKTAGLGIYDLRSGRQIRYLDLGALDTTRPHFGNDVALAHDGTAYVTDSRSGA
                     IYRVPVHGAPTILVRDDRLTPVGAGNGANGIILHPSGFLLVANSSGRTLWRIPLRNPEN
                     ITQVTVNEPIGALDGLLLSGPTTLDGIDNTRTNTRLLRLTSTDNWQTATLKAQIPWADP
                     APTTMARSRCGTYVLSGRLDLLLSGTRSDEFRLRALRF"
     gene            14105..16942
                     /locus_tag="BN1199_RS37045"
     CDS             14105..16942
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005152179.1"
                     /locus_tag="BN1199_RS37045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_063779352.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.6e-16, bitscore:
                     56.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAVRLNRRFLAASLGVLLSLGIVTPAAAAPDPADKAAADAART
                     AAQQISALQELKRSQTPTESKLDTSLLVAKRGAEAAGRGLRAAVPALQTGVPADKVTVD
                     IRGTASGDLLDHLRKVGAGIRSVSEHYRSVRAEVPVNAVEGIAARKDVTFVEPAVGAMT
                     ARQLAAPNGKQAAKDKPSKEAKAKLVAERTRAALSVKAEPVVSEGDRAHNADKARQQFG
                     VTGVGVKICALSDGVDALRASQASGELPADVDVLLGEGGSGDEGTAMLEIIHDLVPNAR
                     LGFATAFRSDASFADNIRKLRFQAKCDIIVDDVVYFKESVFQDWIIAQAVNDVTAAGAL
                     YFSSAGNEGNVADGTAAHWEGDFVDSGLPIGKWAGTAHNFAGTNGVQIYQPISDASSAD
                     VPVLLNWSDPNGGSANDYDLYLLDRGGNVISASQNFQSGAQDPYERVQTPRFGGQGLRV
                     AIVKFKGENRYLSLSALRGRFKDTAGVLTAYNTPGEIFGHAAAKDAFAVAAAPAANPLP
                     FDLEPGDPPNPKGPFPGSFGPTSKVERFTSDGPRRIIYNADGTPITPGNVSSTGGVVRQ
                     KPEITAADGVSTTAPDFETFFGTSAAAPHAAAIAGLVLSGNPGITPADVREALTTTSVD
                     IEQRGFDNRAGSGILLADKVLAYTGASPQPLAEAQAPTVRANDGGAFIDPGDSATVTLP
                     VTNRGDGLAASTSVVLSSPTAGVTIAPRSKFYGSIDKGQTAINNFTVTVPTGHPLGVPV
                     VLDAKVTFAGSQSPTTSRFSFKVGQPSTVVRDFAYTGAALAIPDNDPTGVSVPVQVSGI
                     GRASRVTLSIDGTQCTTDVGATTVGIDHTFVGDLVGTLRSPGGATATLFSGNGSSGDNL
                     CKVVFDDNAAQSFGNLTSDQAPFTGTWRPTQTLDSVLAEADGTWTLHVRDTANRDTGSL
                     RAFSLHVSGFVTPGS"
     misc_feature    14138..14140
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16979..18205)
                     /locus_tag="BN1199_RS37050"
     CDS             complement(16979..18205)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097922.1"
                     /locus_tag="BN1199_RS37050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="low temperature requirement protein A"
                     /protein_id="WP_042192088.1"
                     /transl_table=11
                     /translation="MSKPPTSKPRGSRMERIGESSSATNLELFFDLVFVFALTQVTALM
                     AETPTGEGLLRGALLLSVIWWSWIGYSWLSNLVKADEGPARTAMLAAMAAMFLLALAIP
                     EAYVDLPGGLDGPLVLAFCYLLVRVVHVWLFWLAAEDDAGLRAQILRFVPSMIGGTTLL
                     AIASQLTGPAQIALWAAAGLADYGGTFLIGTSGWRLNSARHFAERYGLIIMIALGESIV
                     AIGVGVTHLAISWPIVLAAVLGLAIAGALWWSYFDTHVIICERALADAQGDERVSMGRT
                     AFTYLHLPLMIGIVLLALGLKKVLGYVGGENGHTLSDPLYGAPLWAMYGGVALFMFGYA
                     GVAWRCIRSLKVQRVVLGAVLLALVPLVANLPAMASLGVLTALLIGLVVYEWFKYHELR
                     HEIRHAQHH"
     gene            18394..20022
                     /locus_tag="BN1199_RS37055"
     CDS             18394..20022
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645324.1"
                     /locus_tag="BN1199_RS37055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_042192090.1"
                     /transl_table=11
                     /translation="MITAIDLELRAGSRILLSETTLRVQPGDRIGLVGRNGAGKTTSLR
                     VLAGEGQPYAGAVRRTSEVGYLPQDPREGDLSVTAKDRVLSARGLDQLLREMEKAQTAM
                     AELVDERARDTAVVKYGKLEERFAALGGYAAESEAARICSNLGLADRVLAQPLRTLSGG
                     QRRRVELSRILFAASDAGAGGKSSTILLLDEPTNHLDADSINWLRGFLKSHDGGLIVIS
                     HDVELLEAVVNKVWFLDANRSELDLYNMGWKKYLEARATDEKRRRRERANAEKKAGALM
                     AQADKMRAKATKAVAAQNMAKRAGKLLAGLEDKRQSDKVARITFPDPAPCGKTPLTAEG
                     LTKVYGSLEVFTGVDLAIDRGSKVVVLGLNGAGKTTLLRLLGGREAADAGTVLPGHGMR
                     LGYYAQEHETLDHEASVWQNIRHAAPDTPEQQLRTLLGTFLFTGEQLDQPAGTLSGGEK
                     TRLALAGLVSSAANVLLLDEPTNNLDPASREQVLDALRRYSGAVVLVTHDPGAVEALEP
                     ERVILLPDGTEDHWSPDYLELVQLA"
     misc_feature    18397..18411
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 20.1"
                     /tool="antismash"
     misc_feature    20093..20105
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     misc_feature    20094..20103
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     gene            20195..20404
                     /locus_tag="BN1199_RS37060"
     CDS             20195..20404
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003071237.1"
                     /locus_tag="BN1199_RS37060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_033391619.1"
                     /transl_table=11
                     /translation="MADLKKGARITGSTRDKLAADLKKKYEKGASIRALAESTGRSYGF
                     VHRVLSESGVQLRGRGGATRTKKK"
     misc_feature    20957..20971
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 gaacgacagg aaccacggcc cgccgctggc accgccggtc tggttgcacg tcatcccgat
       61 gtcctgtgac agcaggaagt cgttgaacac cttaccgctg cagtagatca gcttcgtccc
      121 gtcgtacggc gccgcggccg ggtagccgaa cgcgtacatg ttctgcccgc gtgcctggtt
      181 gaacgcgatg ccctgagcgc cgacgacgtc ggtcaggttc tggccgttga gctggttcac
      241 cacggccgcg cccacgtcgt agttgatgtc ctcactggcg acccactgtg gagtggcgct
      301 ggtgctcttc gcggtccacg tgccgtaggg cgtgttcccg ttgtcgtagc cgggcacgaa
      361 cgcccagttg gtgtggaacg cgccctccag cttcacacaa tggcccgcgg tgatgaccgt
      421 gctcttgttc gcgctggtca ccgcgttgcc gctgcaggag gctgtgcggt tctgataggt
      481 gaagaacacg cggcccgcgg tcttgacgac cgcgccgccg ccggtccacg ccgcgccgcc
      541 gttcgggatg gacaacggga gcgcgccctg gaccacggca ggcagcccgc gtgccacgtc
      601 cttgaccgcg ccgggcgcga ccttgagcag atcgagcggt gccgcggaac gcatccgttc
      661 aggcgtccag aacgccgtca cggccctcgc cgcgttcgcg gtggtcgccg cgaaatgcgt
      721 agtggccgcg ctcttcgcct gtgctgcggg cgtgctgagc gcggccactg tcaatccggt
      781 tgcggctaag acgattagtt tcttcatcgc cagctctctt ccggtggggg agcagggtta
      841 ctcgaaagta actcgcgatt caccgggtgg ccagcctgga acggttcagt ccgccggaca
      901 ggtttgggcc agtcagccca gatcgcgcag ccactgctcg accccggcca cgtgcaccgt
      961 ggcccacgaa cgggcgagct ccggctggcg tgcctccagc gccgcgacga tcgcgcggtg
     1021 ctcggcgact gtccggtcca ccgcgccgcc ctgcgagatg ccgcgccaga tccggacacg
     1081 gaccgtggga ccggccagcg tgtccatcag ctgtgccagg tagctgttgc ccgccgcggt
     1141 gacgatccgg cggtggaact gcaggtcgtg ctcgaccagt tcctcgaccg acccggcctg
     1201 ctcggtggcg tcgcagagct tgcgcagctc ctcgatgtcc tcctcgctga ccgacagggc
     1261 cgccgtcgcg gtggccgcgg gttcgaggat ccggcgaacc tccagcatct ccagcaccga
     1321 ctcctcgctg cggtgcaggt ccagcacgaa cgacagcgcg ccgagcaact cgcccgcgcg
     1381 caggctggag acgtacgtcc cgtcgccctg gcgcacgtcg agcaccctga ccagtgacag
     1441 tgcccggacg gcctcgcgca gcgagttgcg tgacaggccg aggcggtcgg cgaggtcggc
     1501 ctctcgcggc aggcggtcgc ccggcttcag ttcgccggac atgatcattt cccggacccg
     1561 caggatcgcg tcgtcggtta ccgccacggc caacccctca tgagacatcg gatgtcttgg
     1621 cctcccagta tgcctcattc gtgccggggc accgcccgag agactggctt catgagactg
     1681 ggcgtgtttc tcctggcagg acgctttccc gggcaggacg accgggacgc gctgcggcgg
     1741 gccggtgatg cggtcgggtg ggccgagcag gccggattcg acgacgtgtg gatcgccgag
     1801 caccacttca tgtcgtacgg cgtctgcccg tcggcgatca ccttcgcggc acacgccctg
     1861 gggcgtaccg agcggatcac ggtcggcacg gcggtcagcg tgctgtccac gacgcacccg
     1921 gtgatgctcg ccgagcaggt cacgatgctc gaccagatgt ccggcggcag gctgcacctc
     1981 ggcgtggggc gcggcgggcc gtggcgtgat cttgaggtgt tcggcgccgg gctggaccgc
     2041 tgggagaacg ggttcgccga gagcctcgac ctgctggtcg agtgcctgac cgagccgagc
     2101 gtggcgggca ccggccggtt cgagttccgt gcggtgccga tggtgccgca acccgtgcgg
     2161 cggccccgcc tgaccgtcgc gtgcacgtca ccgggcacgg tggcgatcgc cgccgaacgc
     2221 gacctgccga tgctgctggg gatggacctc gacgaccggg gcaaggccgc catggtcgac
     2281 gcctacaccg ccgccggtgg ccgggcgagc gggcacatcg gcgcggcgct cgcgcacgtc
     2341 gccgacagcc gcgcgcaggc ggaggccgaa ctgcgggccg ccatgccgag ctggctggga
     2401 cccggcctga aaggctatgt gacagtggac gaccggcctc gcaagccgca cgacccggcc
     2461 gggtacaccg agcacctgat tcggatcagc ccggtcggca ccgccgagga ctgcctggaa
     2521 cacctgcgcc gcggcacgtc cggcgtcgaa caccacatcc tgatggtcga cgcgtgtggc
     2581 gacccgcaga ccacgcgccg caccatcgaa cgcctcggcg aggccaggtc accctcgtga
     2641 gtgttttcgc cggttagaac cggagaaaac actcacgagg tctttttagc gctggtcgcg
     2701 gaaggcggcg aacagcagtc gcagtccgat caggatgctg atcaccagca ggttgtagcc
     2761 gatcacctgg tacagcgtga tgtcctcgac caggcgcggg ccgccggtgg tgcccagcag
     2821 cagcacggcc atgattcccg ttgtcgcgcc gatgaacgcg agcatcaact ggtgcacgat
     2881 gccgttgagc agttggcggt cgcgttcgtc ggcgaacagc cggacgttga ccgacagcct
     2941 gccttcctcc agtgcgccgc cgatccggtc gatccggcgt ggcagcctgc gcagcacggg
     3001 cagcagcgtc agcagctcct cggtcacggt cttgcgcagg gacgccgggt ccatctgctc
     3061 gctcagccgg accgaggcgt acgcccggga ctcgaccacg atgttgaagc ccggtgcgag
     3121 cccggcgagc gttccctcca tggtggccag tgcgcggaac accgccgcga tctccggcgg
     3181 cacgctcagc ccgtacctgg tgaccaggcg gaacaggtcg gtgaacatct cgacgtcggg
     3241 cgcggcgccg ccggtgaagt gccgtgcgat gaactggccg agcgcgcgct ccagcttctg
     3301 ctcgtcgatg tcgtccggcc gggacaccac ttcgagcagc ccgtcgcgca gcgccgccgg
     3361 atcgccgcgg tcgatggcga gcagcaggtt ctgcagcccg gtgcgcagcg atccgtccag
     3421 cctgccgacc gagccgaagt ccagcaggcc gagcgttccg tcgtccagca gcatcacgtt
     3481 gccggggtgc gggtccgcgt ggaacacgcc gttgcgcatc acctggcgca gcaggcagtg
     3541 cagcagcgaa cgggccagtt cggtgcggtc gagcccgcgc gcgtcgatca gcgcacccgc
     3601 cgagcccagc ggggtgcccg ccagcctgct catgatcagc acccgggtcg tcgcgcggtg
     3661 cacgacgggc accttgacgt ccgcgtcggc cgcgaccgcc tggatgttct tggcctcgcc
     3721 ccggaagtcg agctcctcca gcagggcctt ggcgaacccg tcggcgaggg cgagcacacc
     3781 gagcctgcgg gcccactgcg tgcgctcctc gagggtctgc gcgaggcggt acatgatgtc
     3841 caggtcccgt tcgacgatcg agcggatgcc cggtcgctgc accttcacca cgacatccgt
     3901 gccgtcggtc agctgtgccc ggtagacctg ggcgaccgac gcggacgcca gcggcgccgt
     3961 gtcgatctcg gcgaacacgc cgtccgggtc gcccagttcg tcgcgcagga ccgtgtcgat
     4021 ctcctcgcgc ggggcggggg agacctggtc ctgcagcctg ctcagctcct cgacgaactc
     4081 cggcgggagc aggtcggcgc gggtggacag gacctggccg agcttgacga acgtgacacc
     4141 ggcctcctcc agcgcctgcc gcagcgaccg ggccacctgc gagcgtttga ccgggtcgct
     4201 ggtgcgcaac cggccgcgca gcgccgggcc gagaccgtgc ctgagagcga tcctggtgat
     4261 cctggagtag cgcctggccc ggctgatccg gccgggcagg gaacgcagcc cgccgacgaa
     4321 ccagatcccg gtcccggtcg gcttcatcac ctccagcacg aacaggatcg cgacggcgac
     4381 cagcagcacg ccgccgaaga cggggatgat gaacagcagg gcgatctctt ccgaccccga
     4441 ctcgaacacc gtcggcatct ggccgccgat gaacccggcc gtgctccacg ccgcgaacgc
     4501 cgcgagcacc gcccggatcg tgccgacgcg cacgcccagc accttgcggg cacccacgac
     4561 cagcacccac gcggacagca ccagcaccag gacgcccacg agcgaaaaca gcacgtacca
     4621 catggtcgga acccaaccag acggacgtat cagccgatga ggtgacccgg tttcagacct
     4681 gggagtgagc cgcccgcccg gtcgacgtgt gaggatcacg ctgtggttgg ggtgatcagg
     4741 gcgatcttcg ggccggtcgg ctggaagctg acctaccggc ggtggacgta tctcgtgctg
     4801 ggggcggccc tcatcgtgcc cttcgcgttc gccggtgtgg cgatcgtgcc gccggtgctg
     4861 cgcctgctgc tgcccgccga caccgccgaa cagccgctgg tcgtcgcggt gacgatggcg
     4921 ctggcgatcg tcgtgtgggc ggcgggaacg tcgttcatcc cggccgtgcg ggtggtcgaa
     4981 ggcaccgccg cgcgggaact gctcggctcg ggcgtgccca tccaggcgtc gatgcgggca
     5041 acgaacctgg aggcgcggtg gaagacgtgc cagtggttcc tggtgcacat cgtggtcggc
     5101 gcggtcatcg gcgcgctcac actgttcgtc ccgatcggcc tgctgcagtc gttcgtggcg
     5161 cccttcaccg gcgaatggct ggtcatccag gattcaccgg tgcgcgttcc ggccgggtgg
     5221 cagtcggcgt ggatcccggc cgtcgccgtc gtcatgacgg tcctgctcgt gcacctggtg
     5281 aacctggccg gagtggggat gacgaagctc tcgcaggtgc tgctcggccc gacccccgcc
     5341 gaccacctcg ccgaactcaa gcagcgcgcc gagcaactcg ccgaacgcaa ccggctggcc
     5401 agggaactgc acgactcggt cgggcacgcg ctgagcgtgg tcaccatcca ggccagtgcc
     5461 gccgggcggg tgctcgacac cgacccgaag ttcgcgcagc gcgcgctgtc ggccatcgag
     5521 gagtccgccc gtgccgcgct cgccgacctg gaccacgtcc tcggtctgct cagggaggac
     5581 aagccgggta cacagccgca gcacacactg gccgacctcg atcacctgct cggtaccatt
     5641 cggctggccg gggtcaccgt cgagaccacg atcaccggtg acgtgcccgg cctgccgttc
     5701 gcggtgtcga ccgaggcgta ccggatcgtg caggagtgcc tgacgaacgc gttgaaacac
     5761 gcgggaaagg tcacggtgac gttgggagtc gcggcaggcc acgatgcgct ggaggtggtg
     5821 gcggccaacc cgttgaccgg ccacccctcg ccgccgcgcg gtggtcgcgg tatcgcgggc
     5881 atgcgcgagc gcgcgactgt cctgcgtgga cagatcgagg ccggtcccga cgcggggacg
     5941 tggcgggtga gagcgaggat tccgctgtga ggattgcgct gtgaggattc cactgtgagg
     6001 tcggtgctgt gacagtcaag gtgctgctcg tcgacgacga ggagctgatc agggcaggcc
     6061 tgcgggcgat catcgacgcc gagccggacc tcggtgtcgt cggcgaggcc gaggacggcg
     6121 ccgacgtgct gccgctggtc accaggctgg cgccggacgt ggtgctgatg gacgtgcgga
     6181 tgcccgcggt ggacggcatc caggccacca ggcacatcct cgaccgcgtg ccgaacccgc
     6241 cgaagatcat cgtcgtgacg acgttcgaga acgacgacta cgtctacgac gcgctgcacg
     6301 ccggagccaa cggtttcctg ctcaaacgag cacggcccgc cgagatcgtg cgggcggtca
     6361 aggtggtcgt cgccggtgac tcgctgctgt tccccgacaa gatcagggca ctggccaaac
     6421 ggcgcgggct ggaacccggc cggtcaggcc tgcgggaggc aggtctgacc gaccgggagg
     6481 ccgaggtgct caggctgatg gccaccgggc tgtccaatgt ggagatatcg gaccggctgt
     6541 tcgtcagtgt gcagacggtg aaaacgcatg tgggcaacgt gctgtcgaag ctgcacgccc
     6601 gcgaccggac ccaggccgtg atcaccgcgt acgaatcggg cttcgtgaca ccgggctagg
     6661 ccctagcgtc gtacctccgc ccatgccttg ctgaggcggt tgaccagttc ggtgaggatg
     6721 tcgtcgggga acccgaacgg gaaacggatg aagttgtcgt gcgcgccgga cgggtcggtc
     6781 gccgcgccgg gaacgacttc gacgccgtgc cgcagcgcgg tctgcgcgaa gatgcgggca
     6841 tcggtgttcg gcagctcgat ccacaacgcg gatccgccgt ccggtgtacg ccaacgccat
     6901 tcgggcagat gctgggtcag cagctcccgc gcccggccga gccgttcccg caactgcgcg
     6961 atcctggtcg cggcgagctc gggcagttgc ggcagcagcc gtgcggccag tgcctggtcc
     7021 agcaccgggc tgccgaggtc ggccagtgcc ttgtgcctgg ccagccgctc ggcggtctcg
     7081 accgacgcgc gcacccagcc gatccgcagg cccgcccaca cggacttggc cagcgacccg
     7141 atcgtgatca cttccgcgtt gctgcctgcg aaagcggcga tcggcggtgg cgcgccgtcg
     7201 gaggcgccga cggtgtacgc gtagtcctcg accaccggta cggcgtaccg cgcggccagt
     7261 tccacgaccc ggcggcgtct gctggtggac atcatcacac cggtcggatt gtggtacgtc
     7321 ggcatgacgt acagcagatc cggctggtgc tcggccatca cccggctgag gatgtccgcc
     7381 ctgatgccct cgttgtccaa ctccaccccg accagccgca ccccggtggc cctgagcacg
     7441 tcgagacagc cgggccagct cggtgtctcc accaccgccg tccagccgcg tctcaggtac
     7501 atctgggtga tcaggccgat cgcctgctgg gcgccggtgg tgatgacgac ctgcttgggc
     7561 tcggtgggca gtcccgccgc ggtcaggtgg gccgcgacgg ccgatctgag ctccggcagt
     7621 ccggccgggt ggtagcccga tccgttgagc agcgcgggca ggtccgcgtg caccaggtcg
     7681 agcagcgctc cgcgcaggtg cggcgcgccg gggtcgtagg ctctggccag cgagatgatc
     7741 tcgcctggcc cttcgttggt gcggttgatg atcggcgtcg ccctgccgaa cacgcgtccc
     7801 tcgacactcg gccggaaccc gggtgggcgg accacccgtg tgccactgcc gcgcctgctg
     7861 tcgaccaggc cgatggagcg cagttcgtcg tacgccgaca ccacggtcgc gcggctcaca
     7921 gcaagagccc gcgccagatc acgctcggac ggcaaccgct caccggcatg cagatcacct
     7981 gcgtggatgg ctcggcgcac ggcctctgcc aacctccggt acagcggcgc ccgcccggct
     8041 gacgtgctcg tccagtcgcc gagaacctcg acgagatcgg agccgtcggt caaacggtcc
     8101 attactcccc ctgaatggcc cgcgatccag ggccacaact ccctctgctc gtgccaacct
     8161 tttcccacac tgatcggtat tctcgtgggt tcgttagcac cccgagcgaa gagttctcgt
     8221 gagtggtttg gccggttagc accggccaac ccactcacga tgtgtgacct ggggtttagg
     8281 cgacgggctg gcgggcctgg ggttgtggcc cgcgtgcggg gcggccacgc agcacgtcca
     8341 cccggtcggt gcccggccgc ccgagcaccc agctggaccc gggaacggcc ttcgcctgct
     8401 tcttcagcgg tgccagcatc gccgacgcgt cacggtagga gccaacggtg ttcgcgccgc
     8461 agaccagcga cgcgagcgac accgtgaccg gcgtgccctc cgcgtaccac tccgtgtcca
     8521 gcagcacccc ggcgagcgcg gagatctcgt cgaggtcggt gacgagcagg aagtcgtccc
     8581 cgccgacgtg gccgaccagc acgttcggca tgctcgccga cgcctcggtg atccggcggc
     8641 cgaaggtcct gatcaggtcg tcgcccgcgg cgaaacccat ggtgtcgttg acggtcttga
     8701 acgcgtcgac gtccagccac gcgatgacga acatctcgtt gtcggcgatg cggcggtcga
     8761 cctcgcgcgc gaccgagtcc gtgcccggca gccgcgtcag cgggttgagc gagacggcct
     8821 gctccacctt catgtcggcg acaccgcgga tcacgtcgct cgcccgcacg acgccgacac
     8881 agcggccgcc ctcgtcggtg actgccacgt cgtcgcccgt gcgttcccag tcggtgtcac
     8941 cgaccagttc gagcaactcc atgccggtcg cctcgcggtc gatcagcagc ggccggtccg
     9001 cgtgccggga cgcctcgcgc ttggcgtgca gcgcgtggcc gtacggcccg gcgacgatca
     9061 gcaggaaccg gctgcggtcg atcgaccact gcggccgcca cgtctcgtcg accaggacga
     9121 tgccgttgat gtccgggcgt tcggcgagcg tggcgcggac ctcctcggcg gtcgcggtga
     9181 ccgggagcat cagcgcgggg tgcaggaagt cggtgacttt cggcggtttc accgcggtga
     9241 cacgcctgcc cgccgcctcg gccagtgtcc ggatgcggct cgggtcgacg atcgagtcgg
     9301 cgaggtactc gccctgtgcc acgcgcacac cgagcctgct cagggtggcg agctggttgt
     9361 cgttggtcac gttgaccgcg gcgagccggg agtcggtgcg cgatgccagg cgaacgagcg
     9421 cgtcgagcat cgcggtggtt gccgcgtcgt ccggggtggc cagcaacttc gactggacct
     9481 tgatcatgtt cggcgcggcc tcggcgatca gcgcgagcgg cacgtcaccg tcgccgatgc
     9541 cgtcgagggc gatccggaac ccctcggcac gcagcttggc gatgccttcg agcagatcgg
     9601 cccggcgggc ctggcagaac ggcgtgccga tctcgaacac gacgtcgctg ctgtgccggt
     9661 tggagtgccg cagcacgggc agcaggtggt gcagcagctc gtccgtgcga gccgctgtcg
     9721 atgccaggat gttgacgtgc agcgggatcg ccggatcctg ccgctcggcg gcgagcagcg
     9781 cgtgccctgc cagcgcgatg tcggtcctgg tcaactgccc cgcccggccg gcagccttga
     9841 acaggctgtg gatggtgccg gacgacggca ccgggagcgc ttctacggcg atgacacgcc
     9901 cagtacgtgt gctgagcaac ggctggaacg cgaagttcat ttcttgcgtc gcggacacgg
     9961 cacacatact gcccaacaag tcccactttc gacgaatacg tcaccgattg ttcatgtgtc
    10021 tgactcgggc aatcaccgat ttggcgcaca ccacgcgtgt tcgaccggat gctttccgga
    10081 agatgcgcag cattgcggcc atcgtcgcgc cgggatcgtc ccggccggaa agatagccac
    10141 gttgtgcgtc gggtggtagg tcaaaaaata actcaaagaa tcgtagcgac tcggcggcgg
    10201 agagtgacaa cagtgtttcc agtccgcagt gcctgaggaa atggaccagc cgggcgcgcc
    10261 gggtccacag cgcgggccac ggatcctcgc ctgcggcgat caccgccgcg atcatcggcg
    10321 cgagccggaa tgcctcgccc acgctgtacc cggcggccgg gtgcacaaaa ccggccgccg
    10381 cgccgaacgg aagcaccgga cctcgtttag gccgtggcgt gtcgatggga aaacgcacgc
    10441 gctcgacgtc ggcggtgtcg atctttatcc cgtaaggatc aaggcgttcc cgcagtgcct
    10501 ggcgcagggc ccggaaatcc attgccgggc gccgcgccaa cgccgtctct tcgagaagga
    10561 ctttgccgcc accgagcggc atcgcgtaca ggaacgtgtt gtggtcggag cgccagtcca
    10621 tgaagatcgc ctcgcccggc gcgaccaccg gcgcggcggt ctgctcgtcc acgatcacgc
    10681 cgtatgccgt ctgttcggcc gtgccaccgc gggaacccat cgcgttcaca acggttttcg
    10741 ccgtgagcac ccggccgtcg gccagttcca gactggtcgc ggtcgcggtg accacccgac
    10801 cgctgacgac cgtgacgttc ttgctcagcg cggccatcag ccgatcgttg tccagaatgg
    10861 cgtagtgccg tgccacgacg tgcggtttgg tggtgtacgc ccgcacgacc ctcggctcgg
    10921 cggcggtgac gtccggcggc agcaacgcca actcgtcgcc ccacaggccg taggtcgcgg
    10981 gccaccgccg cagcggctga ggagccacga tcgtggtctc cagccccagc cgggcacagt
    11041 gcgcggcgag cgcccacccc gacggcccgg cgcccgcgat catgacgtcg ggcatatccc
    11101 gattggatca cgccgtgtcc aagcgctggt gagcgaggtg ctagtaccgt gctgccatga
    11161 gtgacccgag agaggaacga cgttcgcacg gcgctcccgc cgccgcgttc gacctggcga
    11221 ccagtccctt ccgtgtggac agggaccggg tcgcgggatc acccttcttc gcccggctcg
    11281 gcggcgtcac ccaggtggtg agcgcgagtg gttcgggcct gctgcacaac cgactgacgc
    11341 acagcgtgaa ggtcgcgcag gtcgcgcggg ccatcgcgga acggctgggg gccgcgccgc
    11401 agtacgtcgc gatcatcgac tcgctcggcg gctgcgatcc cgacgtcgcc gaagccgccg
    11461 cgctggcgca cgacctcggc cacccgccgt tcggacacct gggcgagcag gtgctcgacc
    11521 gcctggcccg gcaccggttc ggcctggccg acgggttcga gggcaacgcg cagtcgttcc
    11581 ggatcgtcac cacgacggac gtcggcggtc ccgccgtggt cggccttgac ctgaccgcgg
    11641 ccgtgcgcgc cgcgatgctg aagtacccgt ggacccgcct gcaccacccc gagccgcacc
    11701 cgcggttcat gcccgagcca ccgcgcggcg cgtccgagcc gtccgagggg ccgggcaccg
    11761 gatccgggaa gttctccgcg tacgtgaccg aactggacga cctcgaacag gcgcgtgcgc
    11821 cgtacgaagg caggctggcc gactggcagc agaccgtcga ggcgtccgtg atggacactg
    11881 ccgacgacat cgcgtacgcc atccacgaca tcacggactt ccaccggatc ggcgtgctgc
    11941 agcacgcgcc ggtcgcggcc gaactcgggc agtggcaggc gaactcggcc accctgtcct
    12001 ggctgtcgga cgaggaggtc cgccgccagg aacgcatgcc ggggcgctcg ctggagctgc
    12061 tgcgccgcag actgcacgag aaggactcgt ggatcgtcag cgacgaggcg ttccacgtgg
    12121 cggtggccag ggtccgctcg gaactggtcg acgagctgct gtcgacgccg ttcgacggat
    12181 cggtcgaggc cgaacaggcg gtggcccggt tctcactgcg gtggacctca cgcctggtcg
    12241 aggagatgtc cgtggtccag gcgccgccga cgcgctcggg tcacgtgatg ctcgcccgtg
    12301 agcagtggca cgaggtgcag gtgctgaagt tcgtgcaccg gaggttcgtg ctgctgcgcc
    12361 cggatctggc gttgcaccaa cgtggtcagg cccggctggt gaccaagttg gtcgaggcgc
    12421 tggaccagtg gctgggggac aggttcgagg cggacaggct gccacgcagg ctgcacgacc
    12481 tcgtcgagtt ggcgacgtcg gagtacgggg cactggcccg gtcggagccc ggcgtgctcg
    12541 tcggggcgac cggagaggcg ccacagggac gggacgccat ccacggcctc gccaggggac
    12601 gggccgtcat cgacttcgtc gcgtccctca ccgacaggca ggcagtgtcc cttatggacg
    12661 ccctgtccgg gcacagtggt cagccatggt ccgacgcgtt cgtcctgtga ccgcagggga
    12721 ccagctccgc ggtagggacg tcagaagcgc agagccctga ggcggaactc gtccgagcgg
    12781 gttccgctca gcagtagatc cagccttccc gacaacacgt acgtcccgca gcggctcctg
    12841 gccatcgttg tcggggctgg gtccgcccag gggatctgtg ccttgagggt cgcggtctgc
    12901 cagttgtcgg tcgacgtcag ccggagcagc ctggtgttgg ttcgggtgtt gtcgatgccg
    12961 tccagtgtcg tcgggccgga caacaggagg ccgtccagcg cgccgatggg ctcgttcacc
    13021 gtcacctggg tgatgttctc cgggtttcgc aacgggattc gccacagtgt ccggccggac
    13081 gagttggcca ccagtaggaa accgctgggg tgcaggatga tcccgttcgc gccgttgccc
    13141 gcgcccactg gcgtcagacg gtcgtcgcgg accaggatcg tcggtgcgcc gtgcaccggg
    13201 acgcggtaga tcgctccgct gcgggagtcg gtcacgtacg ccgtgccgtc gtgggccagt
    13261 gccacgtcgt tgccgaagtg gggccgtgtg gtgtccaacg cgccgaggtc gaggtatctg
    13321 atctgcctgc ccgagcggag gtcgtagatc ccgagtcccg ccgtcttgcc gttcgtctcc
    13381 ggtgtcgagc cgtcggcgat gccgatgtcg ccgttcaccg cgagcagtcg ccctcgccgt
    13441 tcgtccacgg tcaggcccat ggtggtgagc agcttggggt cgttcaccaa cgtgtgggct
    13501 gagccatccg gccgtacggt cgacactgtc ccgtgggtca ccgagccgat caggaactgg
    13561 tttctggtgg ggtcgtgggc gatgccctcc gggtgcagcg cgtcgccctt gccgaggacg
    13621 aaatccgcac atggcggctg ctccggtgcc gccgctgtgg ccgggagcgg gaacgtgccc
    13681 gccgcgacca gtgccagcac gaccaaccgc caaccactag gtcgtgtctc gaagtccccg
    13741 ttcgatgaga gccgggatcg gggcggttcc tggcgtcgcc gccgcgacgg cgcgaatact
    13801 ggttgtcttt ggctgttgcg gcggtggcgc cagggaccgc atccggcccg gctatcgcgg
    13861 acgggggctt tgagacacgg cctagctgcc atgtccgcaa cgtagccccg ccaacgctgt
    13921 tcgcgtaacc gccgaacgtc ggcgagggcc aggggcttcg ttccgtgacc ggctgccggg
    13981 accgagtcac tcatacggct gctgttcggg gcgtgttcgg ccacataacg tctgcgcgat
    14041 ccggggctgt cccgggatcg tccgcgtgtg tcggggcacg cgtcggagta ctgggagggg
    14101 actagtgcgt gctgccgttc ggctgaatcg aagattctta gccgcgtcac tgggtgttct
    14161 tctttcgctt ggcatcgtca cgcccgcagc tgccgcgccg gatccggcgg acaaggctgc
    14221 cgccgacgcc gcgcggaccg cggcccaaca gatttccgcg ctgcaggagc tcaaacgctc
    14281 gcagacgccg accgaatcca aactggacac gtcgctgctt gtcgccaagc gcggtgccga
    14341 ggccgccggt cgcggcctgc gggccgccgt tccggccctg cagacgggtg tgcccgccga
    14401 caaggtcact gtggacattc ggggcaccgc gtccggtgac ctgctcgatc accttcgcaa
    14461 ggtcggcgcc gggatccggt cggtgtccga gcactaccgc tcggtgcgcg ccgaggtccc
    14521 ggtcaacgcc gtcgagggca tcgccgcgcg taaggacgtc acgttcgtcg agcccgctgt
    14581 cggcgccatg accgcacggc aactcgccgc tcccaacggg aagcaggccg cgaaggacaa
    14641 gcccagcaag gaagccaaag ccaaactggt cgccgagcgc acgcgagcgg cgctgtcggt
    14701 caaggccgag cccgtggtca gtgagggcga ccgcgcgcac aacgccgaca aggcgcgcca
    14761 gcagttcggc gtcaccggtg tcggcgtgaa gatctgcgcg ttgtccgacg gcgtcgacgc
    14821 gctgcgggcc tcgcaggcat ccggtgagct gcccgccgac gtcgacgtgc tgctcggcga
    14881 gggcggctcc ggcgacgagg gcaccgcgat gctggagatc atccacgacc tcgtgcccaa
    14941 cgccaggctc ggcttcgcca ccgcgttccg gtcggacgcc agcttcgccg acaacatcag
    15001 gaaactccgt ttccaggcca agtgcgacat catcgtcgac gatgtcgtct acttcaagga
    15061 gtcggtgttc caggactgga tcatcgccca ggccgtcaac gacgtcaccg cggccggtgc
    15121 gctgtacttc tcctccgcgg gcaacgaggg caacgtcgcc gacggcaccg ccgcgcactg
    15181 ggagggcgac ttcgtcgact cgggcctgcc gatcggcaag tgggccggta ccgcgcacaa
    15241 cttcgccggg accaacggtg tgcagatcta ccagccgatc tccgacgcct cctccgccga
    15301 cgtcccggta ctgctgaact ggtcggaccc gaacggcggc tcggccaacg actacgacct
    15361 gtacctgctc gaccgcggcg gcaacgtgat ctccgcgagc cagaacttcc aaagtggcgc
    15421 gcaggacccg tacgagcgcg tgcagacacc acgcttcggc gggcagggcc tgcgggtggc
    15481 gatcgtgaag ttcaagggcg agaaccgcta cctgtcgctg tcggcgctgc gcggccggtt
    15541 caaggacacc gcgggcgtgt tgaccgccta caacaccccg ggtgagatct tcgggcacgc
    15601 ggcggccaag gacgccttcg ctgtcgcggc ggcccccgcg gccaacccgc tgccgttcga
    15661 cctggaaccg ggcgacccgc ccaacccgaa gggaccgttc cccggctcgt tcggcccgac
    15721 ctccaaggtc gagcggttca cctccgacgg cccgcgccgg atcatctaca acgccgacgg
    15781 aacaccgatc actccgggca acgtctcgtc gaccggtggc gtggtcaggc agaagcccga
    15841 gatcaccgcg gccgacggcg tgagcacgac cgcaccggac ttcgagacgt tcttcggcac
    15901 ctcggccgcc gcgccgcacg ccgcggccat cgcgggcctg gtgctgtcgg gcaacccggg
    15961 catcacgccc gcggacgtcc gcgaggcgct caccaccacg agcgtcgaca tcgaacagcg
    16021 cgggttcgac aaccgggccg gttcgggaat cctgttggcc gacaaggtcc tggcgtacac
    16081 gggcgcgagc ccgcagccgc tggccgaggc gcaggcgccg accgtgcgtg ccaacgacgg
    16141 cggtgcgttc atcgaccccg gtgactccgc gacggtcacc ctgccggtga ccaaccgggg
    16201 cgacggcctg gcggcgtcga cgagcgtcgt gctctcctcg ccgaccgcgg gggtgacgat
    16261 cgcgccgcgg tcgaagttct acggttccat cgacaagggc cagaccgcga tcaacaactt
    16321 cacggtcacc gtgcccaccg gtcacccgct gggcgtgccg gtcgtgctcg acgccaaggt
    16381 gaccttcgcc ggttcgcagt cgccgaccac gtcccggttc tccttcaagg tcggccaacc
    16441 gtccactgtg gtgcgcgact tcgcctacac cggcgcggca ctggcgatcc cggacaacga
    16501 cccgaccggt gtctcggtgc cggtgcaggt cagcgggatc ggccgggcca gccgtgtgac
    16561 gctgtcgatc gacggcaccc agtgcacgac cgacgtcggc gcgacgaccg tcggcatcga
    16621 ccacaccttc gtgggcgatc tcgtcggcac gctccgctcg ccgggcggtg ccacggcgac
    16681 gctgttctcc ggcaacggat ccagcggcga caacctgtgc aaggtcgtct tcgacgacaa
    16741 cgcggcacag tcgttcggca acctcacgtc cgaccaggca ccgttcaccg gtacatggcg
    16801 gccgacccag acgctggaca gcgtcctggc cgaggcggac ggcacatgga ccctccacgt
    16861 gcgcgacacc gccaaccggg acaccggctc gctgcgcgcg ttctcactgc acgtgtcggg
    16921 cttcgtcacg ccgggtagtt gatgtcggtg gggccgggcc gcgcccggcc ccacccgttc
    16981 agtggtgttg cgcgtgccgg atctcgtgcc gcagctcgtg gtacttgaac cactcgtaga
    17041 cgaccaggcc gatcagcagc gcggtcagca caccgaggct ggccatcgcg ggcaggttgg
    17101 ccaccagcgg caccagggcc agcagcacgg cgccgaggac cacccgctgc accttcaggc
    17161 tgcggatgca gcgccacgcc accccggcgt agccgaacat gaacagcgcc acaccgccgt
    17221 acatcgccca cagcggcgcg ccgtagagcg ggtcggacag agtgtggccg ttctcaccgc
    17281 cgacgtaccc aaggaccttt ttcaggccga gggccagcag gacgatgccg atcatcagcg
    17341 gcaggtgcag gtaggtgaac gcggtgcggc ccatgctgac ccgttcgtcg ccctgtgcgt
    17401 cggccagcgc ccgctcgcag atgatcacgt gcgtgtcgaa gtacgaccac cacagcgccc
    17461 cggcgatggc caggccgagc accgccgcca gcacgatcgg ccacgagatc gccaggtggg
    17521 tgacgccgac accgatcgcc acgatcgact cgcccagcgc gatcatgatg atcaggccgt
    17581 agcgctcggc gaagtgccgt gccgagttca gccgccagcc actcgtgccg atcaggaacg
    17641 tgccgccgta gtcggcgagc cccgccgctg cccacagcgc gatctgcgcg gggccggtca
    17701 gctgggacgc gatcgccagc agggtcgtcc cgccgatcat ggacggcacg aaccggagga
    17761 tctgggcacg cagcccggcg tcgtcctcgg cggcgagcca gaacagccag acgtgcacca
    17821 cgcggaccag caggtagcag aacgccagca cgagcggtcc gtccaggcca ccgggcaggt
    17881 cgacgtaggc ctccgggatg gcgagcgcga gcaggaacat cgcggccatc gcggcgagca
    17941 tcgccgtgcg ggcgggcccc tcgtcggcct tgaccaaatt ggacaaccag gagtacccga
    18001 tccacgacca ccagatcacg ctgagcagca gcgccccgcg cagcagtccc tcgccggtcg
    18061 gtgtctccgc catcagggcg gtgacctgcg tcaacgcgaa cacgaagacc aggtcgaaga
    18121 acagctcgag gttggtcgcg ctggaactct cgccgatccg ctccatccgg gagccgcgtg
    18181 gtttgctcgt gggcggcttg ctcatgcgca agatggtgac acgcgatcgg cgaaacgtgc
    18241 gaagcgcccg gcccggcccg tctattgtgg acactgagtg cgcgttgcgg tggccgccgg
    18301 gtcgcgtggg cgtggcaaaa ctcgttcgcc agggtctgta aactagacaa ctgtggtcgc
    18361 caccgcgagc cacctgtcta cggagcccaa ctggtgatca ctgctatcga tctggagctg
    18421 cgcgctggct cgcgcatcct gctctcggaa acgacactgc gtgtccagcc gggcgaccgc
    18481 atcggcctgg tcggccgcaa cggcgcgggc aagaccacct cgttgagggt gctggccggc
    18541 gagggccagc cgtacgcggg cgccgtgcgc cgcaccagcg aggtcggcta cctgccgcag
    18601 gacccccgcg aaggcgacct gtcggtcacg gccaaggacc gggtgctgtc cgcacgtggc
    18661 ctggaccagt tgctgcgcga gatggagaag gcgcagaccg ccatggccga gctggtcgac
    18721 gagcgcgcgc gggacacggc ggtcgtcaag tacggcaagc tggaggagcg gttcgccgcg
    18781 ctcggcgggt acgcggcgga gagcgaggcc gcgcggatct gcagcaacct cggtctggcc
    18841 gaccgggtgc tcgcccagcc gctgcgcacg ctctccggtg gccagcggcg ccgggtggag
    18901 ctgtcgcgga tcctgttcgc cgcctccgac gcgggcgcgg gcggcaagtc cagcacgatc
    18961 ctgctgctcg acgaaccgac caaccacctc gacgcggact cgatcaactg gctgcgcggc
    19021 ttcctcaagt cgcacgacgg cggactgatc gtgatcagcc acgacgtcga actgctcgag
    19081 gcggtcgtca acaaggtctg gttcctcgac gccaaccgca gcgaactcga tctgtacaac
    19141 atgggctgga agaagtacct cgaagcccgt gccaccgacg agaaacgccg ccgccgcgaa
    19201 cgcgccaacg cggagaagaa ggccggtgcg ctgatggcgc aggccgacaa gatgcgcgcg
    19261 aaggcgacga aggccgtcgc cgcgcagaac atggccaagc gcgccggcaa gctgctggcc
    19321 gggctcgagg acaagcgtca gtccgacaag gtcgccagga tcacgttccc cgaccccgcg
    19381 ccgtgcggca agaccccgct gaccgcggag ggcctgacga aggtctacgg ctcgctcgag
    19441 gtgttcaccg gagtcgacct ggccatcgac cgcggatcca aggtcgtcgt gctcggcctc
    19501 aacggcgcgg gcaagacgac gttgttgcgg ctgctcggcg ggcgggaagc cgccgacgcc
    19561 ggaactgtcc tacccggaca cggcatgcgg ctgggctact acgcgcagga acacgagacc
    19621 ctcgaccacg aggcgagcgt gtggcagaac atccggcacg ccgctccgga cacccctgag
    19681 cagcaacttc gcacgctgct gggcacattc ctgttcaccg gggaacagtt ggaccagccg
    19741 gcggggacgt tgtccggcgg tgagaagacc cggctcgcgc tggccggtct ggtctccagc
    19801 gcggccaacg tgttgctgct cgacgagccg accaacaacc tcgatcccgc cagccgggaa
    19861 caggttctgg acgcgttgcg ccgctactcg ggcgcggtcg tcctcgtcac ccacgacccc
    19921 ggcgcggtcg aggcgctgga gcccgagcgg gtgatcctcc tgccggacgg caccgaagat
    19981 cattggtcgc cagactatct tgagttggtc cagttggcct gaatcccgca cggatgcgcc
    20041 tcgatcatcg gtgatccact cggatggagt agtgcgagtg ggcgacttca tgatgatttt
    20101 tgcaactcgc ctggcgttcc gcgcttccgt gttcgatcat tgcgggcgca ggggtcgcat
    20161 gtgaccctag ttactcgcta cggaaggcgg agacgtggct gacctcaaga aaggcgcgcg
    20221 cattactgga agtacgcgcg acaagctagc cgctgatctg aagaagaagt acgaaaaggg
    20281 tgcaagcatc cgcgctttgg ccgagtcgac gggtcggtcg tacggattcg tgcaccgggt
    20341 tctgtcggag tccggtgtgc agctgcgtgg ccgtggcggt gccacgcgga ccaagaagaa
    20401 gtagcggctg cctggcctgt tctcccagca caccccgggt gttaccgggc ttgcgacaac
    20461 gtcggatcat gcggttcggc cggccgggac gcggcccgct cggccaccgc gaacgtcatt
    20521 gcggcccccc agagcacaag tgggtacacc aggtagcccc agcggctggc aggcaccatc
    20581 aggatggcgg cgccgaggcc gatcgcggcc ttgagcatcg tgtccgagcc ggtcgtcggt
    20641 gggtcaacga acagccagac ggtcagcgcc agcgcggtga gcccgagcag gacgagtgcg
    20701 acgacatgcc ccacttggcc catgctcgag atcagatgcc caggcagagg gctcgccgcc
    20761 ggtgaggtga tcagtccggt tccggacggg aacttgatca cgtgttcgac gaaggctccc
    20821 gggtggacga tcagcaccgg gatgttcagc agcgcggtga ccccgatgac cgcggtgccg
    20881 aacctgagca gagacgcgcg gccggccctg gtggtgacga caaggaaagc gatcaccacc
    20941 acggccggca gcgcactgag cttcatgctc accacgatcg cgagcagaca gccgcaccag
    21001 acggccttgc ggcgcgcggc cagcgccccg gcgaggatga tcagaccgat gatcgccagg
    21061 tccggcccgg cgacagcgaa cgtcagcgcg gtcag
//
