LOCUS       NZ_CDME01000011        22462 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Kibdelosporangium sp. MJ126-NF4, whole genome shotgun sequence.
ACCESSION   NZ_CDME01000011
VERSION     NZ_CDME01000011.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium sp. MJ126-NF4
  ORGANISM  Kibdelosporangium sp. MJ126-NF4
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-NOV-2014) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000826545.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:10:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,648
            CDSs (total)                      :: 10,573
            Genes (coding)                    :: 10,470
            CDSs (with protein)               :: 10,470
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 19 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 5 of 103
            Pseudo Genes (multiple problems)  :: 10 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1068473
            Orig. end                         :: 1090935
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CDME01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22462
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="3"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22462
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22462
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12462](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12462)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            1447..3483
                     /locus_tag="BN1199_RS33450"
     CDS             1447..3483
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013595.4"
                     /locus_tag="BN1199_RS33450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_052478651.1"
                     /transl_table=11
                     /translation="MCAVLLTATLAVAPTANAAQPPSGKITTLAGNGFAGDPNGDGGPA
                     TQARIDTPSGVARDAAGNTYVTEYWSSRVRKIAPNGIITTIAGNGGYGSGPDGGPATKI
                     PLLNPFGVVADAQGNVYFSDAGDHRVRKVAPNGVISTVAGVAGTIPPGGNVGDGGSALL
                     AKLNGPTGLTRDGGGNLYIADTNSNRIRKVDPSGVITTVAGTGIAGNAADQLNHPHGVA
                     VDGRGALWIADTDNNRVLKGTTVVDPGADPLPYNHPKGIAVDPGGNVYVADTGNNRVRS
                     ISFMGRSRPFAGTGSPGFSGDNGSATFATMTAPVAVFVDPAANVIVADQSNNRVRAIAG
                     QPLITRIAGLLGKSYHSGDGGPATSAEIGVPGGVAVDKFGNVFFGDDFADIRKITPQGV
                     ISTFVRGGTNRAGMAFDRNGNLYAAEGDSTIRRYDAAGNSTVVAGKPGVAGFSGDGGPA
                     TAATLGYPGNLTVDNAGNLYIVDTNNFRIRKVDTNGVITTVAGDGVAGAGTDGVQATAS
                     HLAFEGAYSWKSGGVAVDSKGRIYIADFVNNRIRRVDTNGVISTFAGTGQYTEQGPNLD
                     GAQATAIDMGYAYDVKVDAQDNVYFPALSSVLKVGADGVVHVVAGVGRFPGDRAIIRSM
                     YPCLGDGGPAVLADLFFPEKFTLDGAGNMYLPACNLIRKVAAS"
     gene            3660..3896
                     /locus_tag="BN1199_RS56545"
     CDS             3660..3896
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS56545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="DUF3995 domain-containing protein"
                     /protein_id="WP_157528643.1"
                     /transl_table=11
                     /translation="MVDEPRPLPRVRAWGYFGGVWCVLFAVLHIYWAVGGEAGLASSAG
                     VDLATRRPLGFVLLGLWGLIVAPRLNSGDKFER"
     gene            4329..5321
                     /locus_tag="BN1199_RS33455"
     CDS             4329..5321
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009078611.1"
                     /locus_tag="BN1199_RS33455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_042190940.1"
                     /transl_table=11
                     /translation="MITRTTLGSPGLTVSAMGLGCMGMSESYGAADWDGGLATIDRALE
                     LGITFLDTADAYGTGHNEVLVGRAIHGRRDQVQLATKFGIDRSGGDRARRIRGARDYVL
                     RACDASLLRLGVEVIDLYYAHRPPQDVEIEETVGAMAELVEAGKVRHLGLSEVDGELLR
                     RAHTVHPITAVQSEYSLWTRNVEAVTPVMAELGVGLVPYSPLGRGFLTGTLDRSTLGEK
                     DFRRANPRFVGEAGEANEKIAQTVREVADRLGATPAQVALAWVYAQAERLGVAVATIPG
                     TRSPARLEQNAAALELTLDAEALAALDPLSDQVMGERYTPAHTAEVARG"
     misc_feature    5604..5619
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.95"
                     /tool="antismash"
     gene            5723..6103
                     /locus_tag="BN1199_RS33460"
     CDS             5723..6103
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS33460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_042190941.1"
                     /transl_table=11
                     /translation="MDHARHSLDRLRSEFAARQAVMARTVADLQARTRAEAERLRVAEV
                     PTPHEQVADDEQPESWMVAGYGTPTQHGTGGGPVGGLDRLESGELPWKEVFSDTTTDRD
                     ARAIRALFDERLGEVQRMRNGR"
     gene            6108..7178
                     /locus_tag="BN1199_RS33465"
     CDS             6108..7178
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS33465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_042190943.1"
                     /transl_table=11
                     /translation="MSGFRVNSGYLRGYAGQVEADRDHGVAQVSDYAGAHGRNFDRFSG
                     LLEPAQWVESMLVDAWMEMIGKLRQGLTGTADGLRRTADAYDKIDQSTASKLSAFGNLL
                     GEAESDGAPSAGGGAVAGPFTQGANVAMAPPKDENLVQGVYERIEALVGDFTDPVKQVT
                     GYDIIAEWTPVILGDWGALRRHADAWDQVGKAMEAIEADLNLGMGILMPEWQGGEGTNG
                     GAPAFEKHMRDRVILSCTMYKEIAQLNKEGFDYAAISYEAIITNGLWLLEYYGVRFRAV
                     VKKVVKALREVTLNPKTWYDLIDEVISIVNDYIDFIKNTIKALEISIKQLIEMIELAIA
                     EVKTIMTFIEWKAKGN"
     gene            complement(7263..9857)
                     /locus_tag="BN1199_RS33470"
     CDS             complement(7263..9857)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013228686.1"
                     /locus_tag="BN1199_RS33470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_042190945.1"
                     /transl_table=11
                     /translation="MHQYPTHQSVLAFDVEGFSDPYRDDRAQTVIRAEVYHVFQAAFAS
                     ASVPWDLCVHEDRGDGAIIVVPPEVSKVLLLAPLLSSVSAALVDHNRVAKLSERIRLRV
                     SLHAGEIGQDEHGLSGTDLVVACRLLDAEELKLALRHSPVPLAAIVSDGIYDGIVRHHY
                     RDIDPATYHPVSVRVKRSRLHGWIHLPGTTVAPVIAHEPGPVDLPRQLRAPVATFVNRK
                     QELQVLNRARQLVVLAGPPGVGKTAFALHWAHRVHSRFDGGQFYADLGGPGQPVDLAEV
                     LGRFLRALGVGPAGVPVDADEQATMFRSLTAGRRVLVLLDNVASAEQVRALLPGSPSNV
                     TVVTSRSRLGGLAAEGAHFVSLSRLVGSDGVALLARTVGAARIKAEPDAAREIVSLCGG
                     LPLALCVVAARLVSRPKWTVRKAVAELVDERERLTRLTFGDDLSVKAVFDVSYQALSQP
                     AAHLYRLLGLHPGPDFDTGVAAAMLLTTRAHADQLVDELLTANLVEEVDEEHCRFHDLI
                     RLHAQERALAEESAVDRARGTQRILDWYLAGATEAGRVITPHRQGLRRDIEHVPVDRIT
                     FGGHTEALDWLDRERSNLYAAARTAFDQGMRAKAWQLADAMWGLFLYRTHYHDWMRFDL
                     LAVEATRDGQDRSAQAEAEDRLGLLYHALGRNHEALPHMASAARIWRELGQRHRMASST
                     ERFGFAYLDQGEASLAIEHFTRALAAYRELGEQRSVGLALISLGRALITSGRFADAVGH
                     LREAYAELSSLQVADPYNSARALLALGRAESGAGDWTSAQARLEATLTAMRRMEAPLGE
                     ADALWALAELHETIGNRATARRYYERTEEMLTELDNPGVVKVRAQLASLDPP"
     gene            complement(10001..10717)
                     /locus_tag="BN1199_RS33475"
     CDS             complement(10001..10717)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013228687.1"
                     /locus_tag="BN1199_RS33475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_042190947.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.2e-10,
                     bitscore: 37.2, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.3e-07, bitscore: 26.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 4.4e-16, bitscore: 55.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGRFVIPGTVHATPDDRGNLTLLNQATGRWHVLNRTGAEFYQAL
                     HAHQDIQTATDSLVRRHPEVPVGQIQHDVELLVSALVARGLLVPDESFRRQAAGVLMTL
                     PPSVQPNTWRQGFTALVAFPVALLLLRMPFRVTTAAVTRLKHGLCRRKATIAEAQGVLA
                     AARRAGRFHPGRVACLEETLTAVLAAAIIGYRVDWCFGFAVDPRSFHAWIAVDGNPVID
                     NADDPVDSTYRQVLLI"
     aSDomain        complement(10454..10663)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BN1199_RS33475_Stand_Alone_Lasso_RRE.
                     1"
                     /evalue="3.50E-12"
                     /identifier="RREFam002.1"
                     /label="BN1199_RS33475"
                     /locus_tag="BN1199_RS33475"
                     /protein_end="88"
                     /protein_start="18"
                     /score="37.2"
                     /tool="antismash"
                     /translation="GNLTLLNQATGRWHVLNRTGAEFYQALHAHQDIQTATDSLVRRHP
                     EVPVGQIQHDVELLVSALVARGLLV"
     gene            complement(10714..12462)
                     /locus_tag="BN1199_RS55205"
     CDS             complement(10714..12462)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033561.1"
                     /locus_tag="BN1199_RS55205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_157528645.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.9e-30, bitscore:
                     103.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFSGRSARSVSAPQAIELIESDELLVVGGPMGRAVVFGHCFASR
                     DELETGLREFIETGAPKCFNGWPGCYSIAVLQPLSVTLLTDPVGQFPLYLARAGEDVVF
                     GTSASALAALVNAEPDRVTLLATLTSPEASDLFDARSMFAGVERLDAGHMTRITDGHVK
                     SEPYLQLRPNAQVSLAEAAAMLRLSLARAIDARVRAAGLLTSDFSGGLDSTSLAFLAEI
                     RSPRLPVLTYLNESRPVTDDVDHAVRVAKLANGLEHHLIIGTDADLPYQNIDALAEEPH
                     SSAVATGSMKARLEVAAKLGSDLHLVGEGGDIVLGAPAAYLADLGRKRDLPRLWHHCLG
                     WARIRNRSPMSLLSQAITASRTSRSTAFADLAGQIARGRPTGAVTWERDNIAYWTVPHA
                     NWLTAPARRTLAEHVDACGSRLSADDETSVGDVVTSARLRLQALTQRAVRSAGAKSGVA
                     VHAPYLDTDVVHACLALSASRRASITTPKPLLRAALSGLVPELVLTRPTKGDYTADAYQ
                     GIRRAAPVLRRLLENPATADHGLIEPAPVRQTVARAIDGLPTPWGALNQWIAVEVWLRN
                     QSGEAE"
     misc_feature    complement(11857..11859)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11902..11904)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12772..12788)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.84"
                     /tool="antismash"
     gene            12935..14170
                     /locus_tag="BN1199_RS33485"
     CDS             12935..14170
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013228689.1"
                     /locus_tag="BN1199_RS33485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_042190950.1"
                     /transl_table=11
                     /translation="MASTSRTNHDARDLLWTPSDSLKDANRRKIIRAVMLDPSSTQVNI
                     ARITGLSQATVSTVVGELQEEKIFRVDSGGGERGKRIRLGAVRGLAVGIEVNHTGLTVA
                     LRRVDTARVESDTVDFRADQGGRIWILESVRLITELARKTGLDEDHIVSIGLGVPAAVD
                     PRTALVTQVASSLEWNLGGDPRERFRDHFPGVPIIIDNEANLAAYGEYAFGAGKGDAGR
                     NVETMLFVKASTGIGSGLIIGGLIYRGRHGLAGELGHLTMDPTGIVCRCGNRGCLETLV
                     GGARLVEQVRQAYSGYRIDLPTGLEGMIEKAKGGDQVCGRVLHDAGRNIGLALARVCNL
                     LNPEIIVLGGELSRASELLIEPAEQSLRLYALRGMFDHPEPTRIVGSQLGLLAGAQGAL
                     GFALKADTTVGG"
     gene            14694..15842
                     /locus_tag="BN1199_RS33490"
     CDS             14694..15842
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS33490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157528647.1"
                     /transl_table=11
                     /translation="MGVHTPTSLLRLEDITLLLEHDPRVQLIYTQVPDQLGNGVAQTLQ
                     QLEVRTIPWQEAVCQTFDLTISASLHQMGEVAAVRRFTAPHGAGYNKLWPSWATDEPGS
                     VRQVYGLDRRSLLDEHDQPIFDSIVLPHHDHVATLTRQCPEAVAAAVIAGDPCYDRLCA
                     SLSARGKYRSRLGVRDAQTLVAVSSTWGQQSLLGSQRNLLLRLTSELSVTHRVIATLHP
                     AVWSQHGSRQVRTWLRDARAAGMDLIDAGQDWRALVVSADVMVADHSSLAVYASSVKVP
                     LLLSHFAHDEIDPHSVMAELVGRSPRLCPSTPLLEQLDEARRAQPAQWDVSGRRISTVK
                     GQSAAILQRELYQLLNLSEPPTAASWPLVPVPRLVRDVVDLH"
     misc_feature    16007..16021
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            16025..18775
                     /locus_tag="BN1199_RS33495"
     CDS             16025..18775
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639789.1"
                     /locus_tag="BN1199_RS33495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="WP_063779344.1"
                     /transl_table=11
                     /translation="MSTSVTTDAYRIGAGQLAELLGIDPDQGMSAAQVERRRAQFGPNI
                     LPVESDGGALLRFVRQCHDPLVYVLLVSVAVTLSMAHFVDAGVILGVVLLNAVIGYVQE
                     SRARSALDALSRMIPAEAAVVRDGVTVKVPAEDLVPGDVVVLQAGDKVAADVRLVVADS
                     LEVDESALTGESVPVSKDEDVVLPDGTVLADRRNMAYSGTVVTRGAGRGVVVATGVDTE
                     LGLVNKLVGAANATRTPLTRKLTGFSRQLALVIVGLAVVTFGIGLFRGSPAGEMFTAAV
                     ALAVGAIPEGLPAAVTIVLAIGVVRMSRRNAIVRRLPAVETLGGTTVVCTDKTGTLTAN
                     EMTVKAVVVGSRSHEVTGLGYASDGHVEGLDEDARECLLAGALCNDTSLRPADGGWEVV
                     GDPTEAALLVSATKAGVDTSGYSRIDVLPFDSARQLMVTLHRGPDGLVGYIKGAVEQVL
                     ALTGGGDCSLAEQWAATGLRVLAFARFTPLPGVYRIELDDLSGRAVLLGFQVMHDPSRP
                     EALAAVAACRQAGIEVKMITGDHGATARAIADDFGLGQGVVSGTEINATPDDDLARMSV
                     FARVSPEQKLRLVELLQRKGHVVAMTGDGVNDAPALRQADIGVAMGRGGTQAAKEAADM
                     VLADDNFATIEAAVEEGRGVFDNLRKFLAWTLPTNIAEGLVILVAIVAGAVLPILPVQI
                     LWINMTTAVFLGLALAFEPKESGIMLRRPRSPSLPLLTVDLVRRIVLVSLVLVTAAFWM
                     FQGLMDMGAPVAEARTAAINVFVVVQIAYLISCRSLDRFRLGGWNRWLLGGIGLMVGLQ
                     ALITYVPVLNTLFHTAPLTGGVWLVILAAGVAAFFVVEVDKLVWRWGAERNARIRAQKT
                     EGHVRAQFLGDAGGVVRSSTSLCERGRTVESAGRSEVVGSFGPEL"
     gene            18878..19918
                     /locus_tag="BN1199_RS33500"
     CDS             18878..19918
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658865.1"
                     /locus_tag="BN1199_RS33500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetate/propionate family kinase"
                     /protein_id="WP_369805487.1"
                     /transl_table=11
                     /translation="MDGIETERSVVDRWDGVDCAPLLRPQWPKIDVVAVRFVHGGDRRA
                     PVVLDEGILDDLTDFVPLAPLHQPRSLMAAKVMMWGSAPVVACFDTAFHASMAIAARVY
                     GLPRHLTEKYGLRRYGFHGLSCQYAMRRITELIHNNPDRTQALCVHMGAGVSVTAVKNG
                     RSVDTSMGFTPLEGAMMATRSGSVDPGLLVHLLEQKICRVDELSDLLYHQSGLAGMTGT
                     SGDMRDVLAARKCGDQDAALAVEVYVRRIRREIGALAVSLDRLDAVVFTGGVAVHNWEL
                     VREIAQGLEVLNVDVVKRLLAAHGDRVVSPLGQLPRVFMIKDREELELAKQAELTMVRI
                     EQGVTS"
     gene            19915..20880
                     /locus_tag="BN1199_RS33505"
     CDS             19915..20880
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017982920.1"
                     /locus_tag="BN1199_RS33505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_042190956.1"
                     /transl_table=11
                     /translation="MTCPQLRAALEAAVLAPSPHNTQPWRFEVTDGQVDVLLDESRILA
                     VADPDGREARMSCGAALFNVRMSLRAQGLPVHVNLLPVPYRPHLLARVKVSGHLAAKTD
                     ELVLHRAIPHRHTNRRPFRDDPVPGSVRKILRQGALQEGARLVLLDKPGRYHSVATLLR
                     LAENAQRQDAEFQDELRRWVATDLTRLDGVPLLAGGPPPVTEPLVILRQYGSNGTKPPR
                     EYEQEPLLGVLVTHRDEVHDHVRAGQALQRVLLTATAATVSTSFLSAAVESPRIRSALR
                     DLLGDEGYPQAVLRFGYGYQPPHTRRRPVEQVSNCLETPH"
     gene            complement(20915..21721)
                     /locus_tag="BN1199_RS33510"
     CDS             complement(20915..21721)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012791.4"
                     /locus_tag="BN1199_RS33510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="universal stress protein"
                     /protein_id="WP_042190958.1"
                     /transl_table=11
                     /translation="MTRSAPAIRPVPQQRPVRRPRVAVGTDGTPWGDAALTWALRHAAL
                     LNARLRVFASESSDDQAIARRLDAYRWLFASVTVSPDSPVHTLITASKDHDLVIVGYRG
                     RRHGPFGLGRSVVPIISGAQCDAVVVRGEARSVQGEHRWITAALGGRDDEAVIRRAIQF
                     AVRTRSRLRLIHAVPLPGAHTVPANSDPAEILERAHDLVRDIAPDVIPSLHLVRSQPHE
                     AVRTCDRSDLLVLGPGGQPGKLSMVTATALHMAPCPVLVVKSPDPY"
     misc_feature    22344..22353
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
ORIGIN
        1 atcctgaacg ccggggcagg catgcctgcg agcacaaccc agttcaccgc ggccgacccc
       61 gcagcggccg acaaggtgaa caagctcttc aaggggctcg acacggaata ccgcactcgc
      121 atggacaact tcgcgaactc cgtgcgcgac atgcggttcg acgtgttccc gctcgaccgc
      181 agggactacg acatcttccg gccgaccgtc ctgcctcagg cagggatgga caagctgagc
      241 aaactgccga acgcggcaaa gccgtgtacc ccgacccccg gcaggttcga cattcccagg
      301 ccggagaagg ccatgtcggc gacgcccggc gccgagaccg gctaccagtg gtcgatcggc
      361 cggtaccttg accccaactg gaagctcaac ctctgctacg aggcgaccaa gttcagccag
      421 cccgggtgga caaggacgtg tatgagcacc ggctgcgtgc accggtccac gtggtcgctc
      481 gacctgaact tctacgaggt catggagaac gcgcccggcg ggccgtaccg gacctacgtc
      541 caccatgccc gcaagcattt caagttgtgc gagtggtgga cggggaggac cgatcccgcc
      601 ccgaccaact ggcccatcca gtgctcggcc aacgacgaga tctcgccgga caccatcgag
      661 agggcgctga gcgttccgga ctacacgggt cccccgcagc ccgaacgcgg cgtcgagacc
      721 gtgcgcaaca gggacatcca ggacggcggg ttctacccac cggcgggagt cgacccggtc
      781 cgtgacctga tcagcgaccg gaccgcggac tactacaacc tggtggccag caagggggac
      841 gccgcgctgg gcgcacacga gctggacaac ctggtgatgc tgtaccaggc gttcgtcagc
      901 ctcggcatgc cgagggccaa ggtgaacgac gaccagctgc gggcgctgct cttcggcgca
      961 cacgggatac ccgccaacct gcctgccacg cgggagaaca acatgcaggc caactcgttg
     1021 atcgcgagta cctacgccga agcggcgctc gccgtcaagg ccaacaagta caagggtccg
     1081 ctgccgatgc cgctgttgtc ggacgggaac gagggtgacc cgccgatcga ctgtcgaccg
     1141 ttccaacagg acggtcggga cgcgctgggg gactgtctcg catcggtcgc caagcaacgg
     1201 gccgaccggt tgtacggccg gatcgccctg cacttccagg cgatcgccag cggcgccgag
     1261 tcgccgacat cgccgttgct gcaggaggcg acggacaacc tgaagctcca ggccaggttt
     1321 gccaaggcgt acgcgacgcg atgagccacc gcgggtgggc gacctcgggt cgcccacccg
     1381 tcccatctga cgtgaaacca actggaagcc aaggaaatgc gaagagttct ttccagaacg
     1441 gcgggtatgt gcgccgttct gctgaccgcg acgctggccg tcgcgccgac cgcgaacgcg
     1501 gcccagccgc cgtccggcaa gatcaccacg ttggccggta acggctttgc cggtgacccg
     1561 aacggggacg gtggcccggc cacgcaggcc aggatcgaca ccccgtccgg agttgcccgc
     1621 gacgcggcag gcaacaccta tgtcaccgag tactggagtt cccgcgtccg caagatcgcg
     1681 cccaacggga tcatcaccac cattgccggt aacggcggct acggctccgg cccggacggc
     1741 ggaccggcca ccaagatccc gctgctgaac ccgttcggtg tcgtggcgga cgcacagggc
     1801 aacgtgtact tctcggatgc cggtgaccac cgggtccgca aagtcgcccc gaacggtgtg
     1861 atcagcaccg tcgcgggcgt cgcaggcacc atcccgcccg gcgggaacgt cggcgacggc
     1921 ggctccgcgc tgctggcgaa gctcaacggc cccaccggtc tcacgcggga cggcggcggc
     1981 aacctctaca tcgccgacac gaactccaac cgtatccgca aggtcgaccc gagcggtgtc
     2041 atcaccaccg tcgcgggcac cgggatcgca ggcaacgccg ccgaccagct caaccacccg
     2101 cacggggtgg ccgtcgacgg caggggagcg ctctggatcg cggacactga caacaaccgg
     2161 gtgctcaaag gcaccactgt ggtggacccg ggcgcggatc cgttgccgta caaccacccg
     2221 aaggggatcg cggtcgatcc cggcggcaac gtgtacgtgg ccgacacagg caacaaccgg
     2281 gtccggtcca tcagcttcat gggcaggagc cgccccttcg ccgggaccgg ctcgccgggc
     2341 ttctccggcg acaacggctc ggccaccttc gccaccatga ccgccccggt cgcggtgttc
     2401 gtcgacccgg cggccaacgt gatcgtcgcg gaccagagca acaaccgggt ccgggccatc
     2461 gcggggcagc cgttgatcac caggatcgcc gggctcctcg gcaagtccta ccacagcggc
     2521 gacggcggcc cggccacctc ggcggagatc ggcgtccccg gtggggtcgc tgtggacaag
     2581 ttcggcaacg tcttcttcgg cgacgacttc gccgacatcc gcaagatcac cccacagggc
     2641 gtcatcagca ccttcgtccg cggcggcacc aaccgcgcgg gaatggcctt cgaccgcaac
     2701 ggaaacctct acgccgccga aggcgacagc acgatccgcc gctacgacgc cgcgggcaac
     2761 tcgacagtcg tcgccggtaa gcccggtgtc gcggggttct ccggtgacgg cgggcccgcg
     2821 accgcggcga ccctgggcta tcccggcaac ctgaccgtcg acaacgccgg caacctgtac
     2881 atcgtggaca ccaacaactt ccggatccgc aaggtggaca ccaacggcgt gatcaccacg
     2941 gtcgccggtg atggcgtcgc aggcgctggc accgacggtg tccaggccac cgcgtcccac
     3001 ctggccttcg agggggcgta cagctggaag agcggcggcg tcgcggtcga cagcaagggt
     3061 cggatctaca tcgcggactt cgtcaacaac cgcatccgcc gggtcgacac gaacggcgtg
     3121 atcagcacgt tcgccggcac cggccagtac accgagcaag gccccaacct ggacggtgcc
     3181 caggcgaccg ccatcgacat gggttacgcc tacgacgtga aggtcgacgc gcaggacaac
     3241 gtgtacttcc cggcgctgtc gagcgtgctc aaggtcgggg cggacggtgt cgtgcacgtg
     3301 gtggccggtg tgggccggtt ccccggcgac cgggccatta tcaggagcat gtacccgtgc
     3361 ctgggtgacg gcgggccggc cgtgctggcc gacctgttct tcccggagaa gttcacgctc
     3421 gacggggccg ggaacatgta cctccccgcc tgcaacctga tccgcaaggt cgccgcgagc
     3481 tgacaccacc cgttcgggcc acccgccacc tggcggatgg cccgaacatc gcacgatcgg
     3541 ccgcaccaag gaccaggtgg cgaccgtgtc cgtggtcatg ccggtgcgtt cgatccctca
     3601 cgatcgtcag tcatggtggg gaacctgatt ggctggttca ccgttgcgcg ggtgtgacca
     3661 tggtcgacga accgcgtccg ctcccacgtg tacgggcctg gggatacttc ggcggcgtgt
     3721 ggtgtgtcct ctttgcggtg ctgcatatct actgggcggt gggtggcgag gcgggactgg
     3781 cttcgtcggc gggagtcgat ctcgcgactc gccgaccgct ggggttcgtg ctgctcggtt
     3841 tgtggggcct tatcgtcgca ccgcgattga attcgggcga taagttcgag cggtgaaccg
     3901 gatctgcgtt ggtatgaccc ggatcatcgc ggacattcag ccctgatccg cctcgggcgg
     3961 ctgtgtgtga tcgccggagg cgcggtgctc atggtggtcc ggctggcggt gtagtccggg
     4021 agcagtgcgg caaaagcttg cgggacaggc gaaggcgggt cgccaagacg gatcaggacc
     4081 tggtcggcat cttcgatgat gtcgtcgatg gggagacgga cgatgcggct gactggctgg
     4141 gcgtggagca gcaacaggcc gggcggcgac tctgctgcgc agcggcgcgt cggcgtgggt
     4201 gaggatctcg cccaggcggg ggccggtcct ccggcttgac ctggagcgcg ctccaagtcc
     4261 tagcgtcgga ggcgttcgtc agccctcgag gtaccgcccg gcccgccggg caggaggagt
     4321 atccgcacat gatcacccga accacgctcg gctcgcccgg tctcaccgtc agcgcgatgg
     4381 gcctggggtg catggggatg agcgagagct acggcgccgc cgactgggac ggcggcctgg
     4441 ccaccatcga ccgggccctg gagctgggca tcacgttcct ggacaccgcc gacgcctacg
     4501 gcaccgggca caacgaggtg ctggtgggcc gggccatcca cggccgccgg gaccaggtgc
     4561 agctggccac caagttcggc atcgaccgca gcggcggcga ccgggcacgt cgcatccgtg
     4621 gtgcccggga ttacgtgctg cgcgcctgcg acgcctcgct gctgcggctg ggcgtcgagg
     4681 tgatcgacct gtactacgcc caccgcccgc cccaggacgt ggagatcgag gagaccgtcg
     4741 gggcgatggc cgagctggtc gaggcgggca aggtccgcca cctgggcctg tccgaggtcg
     4801 acggcgagct gctgcgccgg gcgcacacgg tgcacccgat cacagcggtg cagagcgagt
     4861 actcgctgtg gacccgcaac gtcgaggcgg tcaccccggt gatggccgag ctgggggtcg
     4921 ggttggtgcc gtactcgccg ttggggcggg ggttcctgac cggcaccctg gaccgctcca
     4981 cgctgggcga gaaggacttc cggcgcgcca acccccgctt tgtcggcgag gcgggcgagg
     5041 ccaacgagaa gatcgcgcag accgtgcgcg aggtggccga ccggctgggt gcaaccccgg
     5101 cccaggtggc gctggcctgg gtgtacgccc aggccgagcg gctcggggtg gcggtggcga
     5161 ccattccggg cacccgcagc ccggcccggt tggagcagaa cgcggccgcg ctggagctca
     5221 ccctggacgc cgaggcgctg gccgcgctgg acccgctgag cgaccaggtg atgggcgagc
     5281 gctatacccc cgcgcacacc gctgaggtcg ctcggggtta gccggtgggc tcgacggcca
     5341 ggatcgcgcc ccggttgccg gagcccggga gatctcgccg gaggagaccg gcgcccggta
     5401 cccgtccgcg cccaccgcga gcacgccgac gcccgaactc cctgcggcac caacgaaacg
     5461 cggcgaactg gggacagttg aatccgggag gacgccggta cagggtaccc cgtccctgaa
     5521 ctgggccttg tcgaatctgg tgcggctggt gaactgagcc ttctcgaaca ccgcacagtc
     5581 ggcgaacaat ccccgatgga cattgcacgg ttcttgcacg gggcgggccg cggtgaaagc
     5641 cgggggcaaa ctcgatttgg caaggtgtcg caggtctgca cgacggtgtg ggcacgatga
     5701 ccttgccagg gggaaacgaa ccatggatca cgcacgccac agcctcgacc gcctcaggtc
     5761 ggagttcgcg gcaaggcagg cggtgatggc ccggacagtg gctgaccttc aggcgcggac
     5821 ccgcgcggag gccgaacggc tgcgcgtggc cgaggtgccg acacctcacg agcaggtggc
     5881 tgacgacgag cagccggagt cgtggatggt cgccggttac ggcacgccca cccagcacgg
     5941 caccggcggc ggcccggtcg gcgggctgga caggctggag agcggcgaac tgccgtggaa
     6001 ggaagtgttc tccgacacca ccaccgaccg ggacgcgaga gccatccgcg ctttgttcga
     6061 cgaacggctc ggcgaggtcc agcggatgcg gaacggcagg taggcacgtg tcagggtttc
     6121 gagtcaacag cgggtatctg cgcggctacg cgggccaggt cgaggccgac cgcgaccacg
     6181 gcgtcgcgca ggtctcggac tacgcgggcg cgcacggccg caacttcgac cggttcagcg
     6241 gcctgctgga accggcccag tgggtcgagt cgatgcttgt cgacgcctgg atggagatga
     6301 tcgggaagct gcggcaaggg ctgaccggta ccgccgacgg cctgcggcgc accgcggacg
     6361 cgtacgacaa gatcgaccag tccaccgcga gcaagctgtc ggcattcggc aatctcctcg
     6421 gcgaagccga gtctgatggc gcgccgtcgg cgggcggcgg cgcggtggcg ggtccgttca
     6481 cgcagggcgc gaacgtcgcc atggccccgc cgaaggacga gaacctggtg cagggtgtct
     6541 acgagcgcat cgaggcgctg gtcggcgact tcaccgaccc ggtcaagcag gtcaccgggt
     6601 acgacatcat cgccgagtgg acgccggtca tcctgggcga ctggggcgcg ttgcgcaggc
     6661 acgccgacgc gtgggaccag gtcgggaagg cgatggaggc catcgaggcg gacctcaacc
     6721 tcggcatggg catcctcatg ccggaatggc agggcggcga gggcacgaac ggcggggcgc
     6781 ccgcgttcga gaaacacatg cgtgaccggg tcatcctgag ctgcaccatg tacaaggaga
     6841 tcgcccaact caacaaggag ggcttcgact acgcggcgat cagctacgag gcgatcatca
     6901 ccaacggcct gtggctgctg gagtactacg gcgtgcggtt cagggcggtc gtgaagaagg
     6961 tcgtcaaggc gctgcgggag gtcacgctca acccgaagac ctggtacgac ctgatcgacg
     7021 aggtgatctc gatcgtcaac gactacatcg atttcatcaa gaacaccatc aaggccctcg
     7081 aaatcagcat caagcagctc atcgagatga tcgaactggc catcgccgag gtgaagacca
     7141 tcatgacatt catcgagtgg aaggcgaagg gcaactgacg cgtacccggg gtaaccctgg
     7201 cgtaagggaa ctgccagaca ccagcctccc agccgcaggc accgtaacca agcagcgacc
     7261 ctctacgggg ggtcgaggct ggcgagttgt gctctgacct tgaccacccc ggggttgtcc
     7321 agttcggtga gcatttcctc ggtgcgctcg tagtagcggc gggccgtcgc gcggttcccg
     7381 atcgtctcgt ggagttcggc cagcgcccac aaggcgtccg cttcaccgag gggcgcttcc
     7441 atcctgcgca tggcggtgag agtcgcttcg agacgtgcct gggccgatgt ccagtcgccg
     7501 gcgccgctct cggcacggcc cagtgcgagc agcgcgcggg cggagttgta ggggtcggcg
     7561 acctggaggg agctgagttc ggcgtacgcc tcgcggaggt gaccgacagc gtcggcgaac
     7621 cggcctgagg tgatcagcgc gcgtcccaga ctgatcaggg ccaggccaac gctgcgctgt
     7681 tcgcccagtt cacggtaggc ggccaaggcg cgggtaaagt gctcgatcgc cagactggcc
     7741 tcgccttggt cgaggtaggc gaagccgaat cgctcggtgg aactggccat acggtgtcgt
     7801 tggcccagtt cgcgccagat cctcgcggcg ctggccatgt gcggcagcgc ttcgtgatta
     7861 cggcccagcg cgtggtagag caggccgagc cggtcctctg cctccgcctg ggcagaacgg
     7921 tcctggccgt cccgggtggc ctccacagcg agcaggtcaa agcgcatcca gtcgtggtag
     7981 tgcgtgcggt agaggaacag gccccacatg gcgtccgcca gttgccatgc cttcgcccgc
     8041 attccctggt cgaaggcggt ccgcgcagcg gcgtagaggt tggacctttc ccggtcgagc
     8101 cagtcgagtg cctcggtgtg gccgccgaac gtgatccggt cgaccgggac gtgctcgatg
     8161 tcccggcgca gcccctggcg gtggggggtg atgacgcgac cggcctcggt cgcaccggcg
     8221 aggtaccagt cgaggatccg ctgcgtcccg cgcgcacggt ccacagcgga ctcttcggcc
     8281 agtgctcgtt cctgtgcgtg caggcggatc aggtcgtgaa accggcagtg ctcctcgtcg
     8341 acctcctcca cgaggttcgc ggtcagcagt tcgtccacca gttggtcggc gtgcgcgcgt
     8401 gtggtcaaga gcattgccgc cgccacaccg gtgtcgaaat cgggtccggg atgcaacccg
     8461 agcaagcggt agaggtgggc tgcaggttgg gagagcgcct gataggacac gtcgaacacc
     8521 gccttcaccg acaagtcgtc gccgaaggtc aacctggtga gccgctcacg ttcgtcgacc
     8581 agttcggcga ctgccttcct tactgtccat tttggacgtg ataccagtcg tgccgccacc
     8641 acgcagaggg cgaggggcag gccgccgcac agcgacacga tctctcgcgc ggcgtcgggt
     8701 tctgccttga tcctggcggc cccgacggtc ctggccagca acgccacccc gtcggagccg
     8761 accaaccggc tgagcgagac gaaatgcgct ccttcggcgg ccagtccgcc gagccgggac
     8821 ctgctggtca ccacggtgac gttcgacggc gagcctggga gcagcgcccg gacctgctcg
     8881 gcggatgcga cgttgtccag caggaccagc acccgtcggc ctgcggtcag cgaacggaac
     8941 atggtcgcct gctcgtcggc gtcgacaggc accccggccg ggccaacgcc cagggcacgc
     9001 aggaaccggc cgagaacctc ggccagatcg accggctggc cggggccacc gaggtcagcg
     9061 tagaactggc ctccgtcgaa ccggctgtgg acccggtgcg cccagtgcag cgcgaaggcc
     9121 gtcttgccga cgcccggcgg cccggcgagc acgacgagct gccgggcccg gttgagcacc
     9181 tgcagctcct gtttccggtt gacgaaagtc gcgacagggg cgcgtagctg tcgtggtagg
     9241 tcgaccgggc cgggttcgtg tgcgatgacg ggtgcgaccg tggtgccggg tagatggatc
     9301 catccgtgca ggcgacttcg cttcaccctg acggaaaccg ggtggtaggt ggccgggtcg
     9361 atgtcgcggt agtggtgacg gacgatgccg tcgtagattc cgtccgagac gatcgccgcg
     9421 agcggaacag gggagtgccg aagcgcaagc ttgagttcct ccgcgtcgag caggcgacac
     9481 gcgaccacga ggtcggtccc ggacaggccg tgctcgtcct gaccgatttc tccggcgtgc
     9541 agcgataccc gaagtcggat tcgctcggac agcttggcga cccggttgtg gtcgaccagt
     9601 gcggcggaca cgctgctcag caggggggcc agcaggagca ccttcgagac ctcgggcggg
     9661 accacgatga tcgcgccgtc gccacggtcc tcgtgaacgc acaggtccca cggcacactg
     9721 gcggaggcga acgccgcctg gaacacgtgg tagacctccg cccggatgac ggtctgggcg
     9781 cggtcgtcgc ggtagggatc actgaagccc tcgacgtcga atgccagcac ggactgatgc
     9841 gtcgggtact ggtgcatcgt ggtctccctg cccaggccaa caggtcagcg cctcctacaa
     9901 gtacacaaga cacgacaggt cgaatgcgtc aagcgacgca ttcgaccccg gagccatgcc
     9961 aggtccattc ctgctacacg acgccgcgac acccagtcgt ctagatcagg agcacttggc
    10021 ggtaggttga gtcgactggg tcgtctgcgt tgtcgatcac cgggttgccg tcgacggcga
    10081 tccaagcgtg aaaggaccgc ggatcgacag cgaagccgaa gcaccagtcc acgcgatagc
    10141 cgatgatggc cgcggccagt actgcggtca gggtctcctc gaggcaggcc acgcggccgg
    10201 ggtggaacct gccggctcgg cgggccgcgg ccagaacacc ttgggcctcg gcgattgtgg
    10261 ccttgcggcg gcagaggccg tgtttcaggc gtgtcacggc ggcggtggtg acgcggaacg
    10321 gcatcctcag caagaggagt gccacgggga acgcgacgag cgcggtgaat ccctgcctcc
    10381 aggtgttggg ctggaccgat gggggcagcg tcatgaggac tccggcggct tggcggcgga
    10441 acgactcgtc agggacaagc agacctcgag ccaccaaggc ggacaccaga agttcgacgt
    10501 cgtgctggat ctgaccgact ggcacctcgg ggtggcgtcg caccaacgag tcggtcgccg
    10561 tctggatgtc ctggtgcgca tgcaatgcct ggtagaactc ggcgcctgtc cggttgagga
    10621 cgtgccagcg accggtcgcc tggttgagca gggtcaagtt ccctctgtcg tccggtgttg
    10681 cgtggacggt cccggggatg acgaatctgc ctctcactct gcctctccag actggttgcg
    10741 gagccacacc tcgacggcga tccactggtt cagcgcgccc cacggcgtcg gcagtccgtc
    10801 gatcgctcgt gcgacggtct gacggacagg tgcgggctcg atcagtccgt ggtccgcggt
    10861 cgccggattt tccaacaagc gccgcaggac gggtgccgcg cggcggatgc cttggtatgc
    10921 gtctgccgtg tagtcgccct tggtcgggcg cgtgagcacc aactcgggaa caagaccgga
    10981 cagcgccgcg cgtaggagcg gttttggcgt ggtgatgctc gctcgtcgcg aggccgacag
    11041 ggccaggcac gcatgaacga catctgtgtc gaggtaaggc gcgtgtaccg caacgccaga
    11101 cttcgcacct gcactccgaa ccgcacgttg tgtcagagcc tgcaaacgga gtctggctga
    11161 ggtcacgaca tcaccaactg aagtttcatc gtctgctgag aggcgggacc cacacgcgtc
    11221 cacgtgctcg gcgagcgtcc tccgtgcggg cgcagtcagc cagttggcat gcggaacagt
    11281 ccagtaggca atgttgtccc tctcccaggt caccgcaccg gttggtcgtc ctcgggcgat
    11341 ttgaccggcc aggtcggcaa atgctgtgct ccggctcgtt ctcgacgcgg tgatggcctg
    11401 agagaggagc gacatcggcg aacggttgcg tatcctcgcc cagccgagac agtggtgcca
    11461 cagtcggggt aggtctcgct ttctgcccaa gtctgccaga taagcggctg gagcgccgag
    11521 cacgatatcg ccgccttcac ctacgagatg caggtctgag ccgagtttgg cggccacctc
    11581 cagccgcgcc ttcatcgaac ccgtcgccac ggcggaggaa tgcggttcct cggcgagcgc
    11641 atcaatgttc tgatacggca gatccgcatc tgttccaatg attaggtgat gctccagtcc
    11701 attcgcgagt ttcgcaacgc ggacagcgtg gtcgacgtcg tccgtgaccg gtcggctctc
    11761 gttgagatac gtgagaactg gaagccgagg agatctgatt tcggcgagaa acgcgagcga
    11821 ggtggaatcg agtcccccgc tgaaatcgga cgtcagtaaa ccggctgccc tgactctggc
    11881 gtcgatcgct ctggccaagg ataatcgaag catggccgca gcttcggcaa gcgaaacctg
    11941 ggcgttgggc cgcagctgca gatacggttc cgatttgaca tggccgtccg tgatgcgggt
    12001 catgtgtccc gcatccagtc gctcgacccc ggcgaacatg gatcgagcat cgaagaggtc
    12061 actcgcttcg ggggaggtca gcgtggccag caacgtgacc cgatcgggct ccgcgttgac
    12121 aagagccgcc agcgcggacg cactcgttcc gaacacgaca tcttcgcccg cccgagccag
    12181 gtagagcggg aactggccga ccggatccgt gagcagggtg acggagagcg gctggagaac
    12241 agcgatcgaa tagcatccgg gccaaccgtt gaaacacttc ggcgcacccg tttcgatgaa
    12301 ctcgcggagg ccggtttcca gctcgtcgcg ggaggcgaag cagtgtccga agacgactgc
    12361 gcgccccatc ggtccaccaa cgaccagaag ttcgtcggat tcaatgagtt caatggcctg
    12421 cggcgctgag acacttcttg ccgatcggcc actgaaacgc actcgtttgc tccctcttgc
    12481 gacacccctc cgtcagtcga acttctgcgc gctcgcgtca ccgcttccgc cggtgcttcc
    12541 gtgagtgact tcccgaacca ggccgaaatc atggatccca ggaggttcgt aaccactctc
    12601 actcggctga tcgtcgcggc gcgattcgac ccggtcgtca gtcacaagcc acctcccgag
    12661 gctcgactcc gggctgtcgc aacccggtca caattggtaa agtctagccg ccgcaactgt
    12721 cacccgccag tgtttgaact tcactattta gtggccctac acgtgagttc tcggtggcaa
    12781 agctccaagg aaccacgcct acgattccgg ctgcgagact cttccaactg gccgaggcgc
    12841 gccaccctag ccaagcgctg gctacaggat tatggtagaa ggtcttccaa ttgaagatgg
    12901 ctctccgtcg gtgggcccct tgactggagg accagtggca tctacgagtc ggacgaacca
    12961 cgacgcgcgt gacttgctct ggacgccgtc cgactcgctg aaggacgcga accggcggaa
    13021 gatcattcgg gccgtgatgc tcgatccgag cagtacgcaa gtgaacatcg cccgcatcac
    13081 cggcctgtcc caggcgacag tatcgaccgt ggtgggcgaa ctccaggagg agaagatctt
    13141 ccgggtcgac tccggtggag gcgagcgcgg gaaacggatc cgcctgggcg ccgtacgggg
    13201 cctggcggtg ggcatcgagg tcaaccacac cggcttgaca gtggcactga ggcgtgtgga
    13261 cacagccagg gtggagtcgg acaccgtcga cttcagagcc gaccagggcg gccggatctg
    13321 gatcttggag agtgtccggc tgatcaccga actcgcgcgc aagaccgggc tcgacgagga
    13381 ccacatcgtg tcgatcgggc tgggtgtccc cgctgccgtc gacccgcgta ccgccttggt
    13441 cacccaggtc gcctcgtcgc tcgagtggaa tctgggtggc gatccccggg agaggttccg
    13501 tgatcacttc cccggtgtgc cgatcatcat cgacaacgag gccaatctgg ccgcatacgg
    13561 cgaatacgcc ttcggcgcgg gcaaggggga cgctggcagg aacgtcgaaa cgatgttgtt
    13621 cgtcaaagcc tcgacaggca tcggatcggg cctgatcatc ggcggtctga tctaccgcgg
    13681 acgccacggc ctggccggcg agctgggcca tctgaccatg gatcccacgg gaatcgtctg
    13741 ccgttgcggc aatcgtggct gcctggagac gttggtcggc ggcgcgcgtc tggtcgagca
    13801 ggtgcggcag gcctattccg gataccggat agacctgccc accgggctgg aaggcatgat
    13861 cgaaaaggcc aagggcgggg atcaggtgtg cggccgggtg ctgcacgacg ccggtcgcaa
    13921 catcggcctg gcgctggcaa gggtgtgcaa cctgctcaac cccgagatca tcgtgcttgg
    13981 cggagagctg agccgagcgt ccgaactgct catcgagccc gccgaacaga gcttgcgcct
    14041 ctatgcgctg cgggggatgt tcgaccaccc cgagccgact cggatcgtgg gatcgcagct
    14101 cggcctcctg gcgggtgctc agggcgcact cggcttcgca ctgaaggcgg acacgacggt
    14161 cggtggctag gacggtttca tcttcaagct tgatgtcacg gtcggttctg aagcagtatt
    14221 gacttcaaat cgaagagtcg tatcctttca actgggaggc ccgtgacgtt cgaaggcgaa
    14281 gacggtgagg gcaatgaggc caatcctcgg gagtgcatgc gtcagtcgat cgatctgcgg
    14341 agcggaagcg ccctgtgccc ggagttctgt gctgcgtacg gcggccaacc tgggccgccg
    14401 cgccagaaaa gtggccgagc tcgcgatcgc gagtcccagg tatttccttc cctccccagt
    14461 gaaagccagg tagcgccatg tcctcccgat cccgccgccg gagaacggcc gaccccggcc
    14521 accatgccac cgaaggtccg aggcgcctga caccacgtag gggcatccca gccggtaggc
    14581 ggacaacggt cccgagccag cgcagcaccc cacctgacgt gctggttccg tgtcccactg
    14641 ccagggcgaa ccgccacaac tggtcgacca tgaacacgga acgcactgtc ctcgtggggg
    14701 ttcacacccc gacaagcctg ctgcggctcg aggacatcac gctgctgctt gagcacgacc
    14761 cgcgggtcca gctgatctac acccaggtgc ctgaccagct gggaaacggt gtggcgcaga
    14821 cgctccagca gctcgaagtg cggacgatcc cgtggcagga ggccgtctgt cagacgttcg
    14881 acctgaccat ctccgcgagc ctgcaccaga tgggcgaagt ggccgctgtc cgccgtttca
    14941 cggctccgca cggagccggc tacaacaagc tctggccctc ctgggccacg gatgagcctg
    15001 gcagcgtgcg gcaggtctac ggactcgacc gccggtccct gctcgacgag cacgaccagc
    15061 cgatcttcga ctcgatcgtg ctcccgcacc acgaccacgt ggcgacactc acccggcagt
    15121 gcccagaagc agtcgcggcg gcggtcatcg ccggagatcc gtgctacgac cggctgtgcg
    15181 catccctgtc ggccaggggc aagtaccggt cgaggctggg tgttcgcgac gcccagaccc
    15241 tggtcgccgt gtcctccacc tgggggcagc agtcactgct gggcagccag cggaatctgt
    15301 tgttgcgact gacttccgaa ctttcagtca cccatcgggt catcgcgacc ctgcacccgg
    15361 cggtgtggtc acaacacggc tctcgccagg tccgcacctg gctgcgcgac gcccgcgcgg
    15421 ccggaatgga cctcatcgac gcagggcagg actggcgagc gttggtggtt tccgcggacg
    15481 tgatggtcgc tgaccacagc tcgttggccg tgtacgcatc gagcgtgaag gtgccgttgc
    15541 tgctcagtca tttcgcccat gacgagatag acccgcactc agtgatggca gagctggtcg
    15601 gccggagccc gcggctgtgt ccatcaacac cgctgctcga acagctggac gaagccaggc
    15661 gggcacaacc cgcccagtgg gacgtgtccg gccgccggat ctcaactgtc aaaggacaat
    15721 ccgccgccat tctccagcgg gagctctacc agttgctcaa tctgtccgag ccccccacgg
    15781 cggcgagctg gccactcgtt ccggtgccac gactcgtaag ggacgtggtc gatctccact
    15841 gactgagcac ggcgcggggg catctccgcg gtatcccggt cggccgccca ccggtacgga
    15901 atgcgagtgg ctgaaccagc gctcgcatat cgtcaggact tgcgggtcgg taaggccgaa
    15961 agaccctgtg acttgccctg atcgcctcta gtggcgtctt tctcggatca cgactcttga
    16021 tggcatgagc acatcggtga caacggacgc gtatcggatc ggcgcggggc aactggctga
    16081 gttgctgggc attgacccgg atcaggggat gtctgccgcg caggtcgagc gccgtcgggc
    16141 tcagttcggg ccgaacatcc tgccggtgga gagtgacggt ggtgctcttc tgcggtttgt
    16201 ccggcagtgt cacgacccgt tggtgtatgt gctgctcgtt tcagtggcgg taacgctgag
    16261 catggcgcac ttcgtcgacg cgggggtcat tctcggtgtc gttctgctga acgcggtgat
    16321 cggatacgtg caggagtcgc gtgctcggtc cgctttggac gcactgtctc ggatgattcc
    16381 tgccgaggcg gccgtggtgc gggacggtgt cacggtcaag gttcccgctg aggatctggt
    16441 tccgggtgat gtcgtggtgt tgcaggcggg ggacaaggtc gcggctgatg tccggcttgt
    16501 ggtggccgac tcgctggagg tcgacgagtc cgcgttgacg ggtgagtccg tgcctgtgtc
    16561 gaaggacgag gatgtggtgc tgccggacgg tacggttctg gcggaccggc ggaacatggc
    16621 ctactccggc acggtggtga ctcgtggtgc ggggcgcggt gtcgttgtgg cgacgggcgt
    16681 ggacaccgag ttgggtttgg tcaacaagct ggtcggtgcc gcgaatgcga cgcggacacc
    16741 gttgacgcgt aagttgaccg gtttcagcag gcagttggcg ttggtcattg tcgggctcgc
    16801 cgtggtgacg ttcggaatcg ggctgtttcg gggaagcccg gcgggggaga tgttcaccgc
    16861 cgctgtggcg ttggcggttg gtgcgattcc cgaagggttg cccgcggcgg tcacgatcgt
    16921 gctggcgatc ggtgtggtgc ggatgtctcg gcggaacgcg attgttcgcc ggttgcccgc
    16981 ggtggagacg ttgggtggga cgaccgtggt gtgtactgac aagacgggaa cgctgacagc
    17041 caatgagatg accgtgaaag cggtcgtggt cggcagtcgg agccatgagg tgaccgggct
    17101 cggatatgcc tcggacggtc acgttgaggg gctggatgag gacgcgcgtg agtgtctgtt
    17161 ggcgggtgcg ttgtgcaacg acacgagcct tcgaccggcg gacggcggct gggaagtcgt
    17221 tggcgacccg acggaggcgg cgctgctggt gtcggcgacc aaagcgggag tcgacacctc
    17281 cgggtactcg cggattgatg ttctcccgtt cgattcggca cggcagttga tggtcacgtt
    17341 gcatcgcggc ccggacggtc tggtcggcta catcaaaggg gcggtcgaac aggtgctggc
    17401 gttgaccggc gggggtgact gttcacttgc cgagcagtgg gccgcgactg gactgcgtgt
    17461 gcttgcgttc gcccggttca cgccgctgcc cggggtgtac cggatcgagt tggacgacct
    17521 gtcgggacgt gctgttctgc ttggctttca ggtcatgcat gatccgtcgc ggccggaagc
    17581 gctcgcggcg gtggccgcgt gcaggcaggc gggcatcgaa gtcaagatga tcactggtga
    17641 ccacggtgcc accgcgcggg cgattgccga cgacttcggc ctgggccagg gcgtcgtgtc
    17701 ggggacagag atcaacgcca cgccggatga cgacttggcg cgaatgtcgg tgttcgcacg
    17761 cgtctcgccg gagcagaagc tgcggctggt ggagttgttg cagcgcaagg ggcatgtggt
    17821 cgcgatgacg ggcgacggcg tgaacgacgc gcccgcgctg cggcaggccg acatcggtgt
    17881 ggcgatggga cgtggtggca cgcaggcggc gaaggaggcc gcggacatgg tcctggccga
    17941 cgacaacttc gccacgatcg aagccgcggt ggaagagggc cgcggcgtgt tcgacaacct
    18001 gcgcaagttt ctggcctgga cgttgccgac caacatcgct gaagggctgg tcatcctcgt
    18061 ggcgatcgtc gcgggtgcgg tgctgccgat cctgccggtg cagatcctgt ggatcaacat
    18121 gaccacggcc gtgttcctgg ggctggcctt ggcgttcgag ccgaaggaat ccggcatcat
    18181 gctgcgccgg ccgcgttcgc ccagtctgcc gctgctcacg gtggacctgg tgcgccggat
    18241 cgtcctggtt tcccttgtcc ttgtgacggc tgctttctgg atgttccaag gcttgatgga
    18301 catgggtgcg ccagtggcgg aagcacggac ggcggcgatc aacgtcttcg tggtcgtgca
    18361 gatcgcctac ctgatcagtt gccggtctct ggaccggttc cggttgggcg ggtggaatcg
    18421 gtggctgttg ggcggaatcg gtctgatggt cggactgcag gcgttgatca cctatgtgcc
    18481 ggtgctgaac accttgttcc acaccgcccc gctgaccggt ggtgtgtggc tggtcattct
    18541 tgccgcggga gtggcggcgt tcttcgtcgt ggaggtcgac aagctggtgt ggcggtgggg
    18601 agcggagcgg aacgcgcgaa ttcgcgccca gaaaaccgaa gggcacgtcc gcgcccagtt
    18661 cctcggcgac gcgggcggcg tagtgcgttc gtcaacgtca ttgtgtgagc gcggcaggac
    18721 ggtggagagt gccggacgat ccgaggtggt ggggtctttc ggccctgagt tgtgagccga
    18781 tcgccactga cccggacgtc tgtcacccag tcacagtgag ggtatgcgtg tgatgacggt
    18841 gaatcccgga tcctccagcc tcaagctgtc gctggtcgtg gacggcatcg agacagagcg
    18901 gtctgtcgtc gaccggtggg atggcgtgga ctgcgcgccg ctgctgcgtc cgcaatggcc
    18961 gaagatcgat gtggtggcag tgcggttcgt gcacggtggc gatcggcgcg cgccagtggt
    19021 tctggacgag gggattctgg acgatctgac cgacttcgtg ccgctcgctc cgctgcacca
    19081 gccgcggtcg ctgatggcgg cgaaggtcat gatgtggggt tcggctcccg tcgtggcgtg
    19141 cttcgacacc gcgttccacg cgtcgatggc catagcggca cgggtttacg gcttgcccag
    19201 gcacttgact gagaagtacg gactgcgccg atacgggttc cacggcttgt catgccagta
    19261 cgcgatgcgt cgtatcaccg agctgataca caacaatccg gaccggacgc aggctctttg
    19321 tgtccatatg ggagcagggg tgtctgtcac cgcggtcaag aatggccgca gtgtcgatac
    19381 gagtatggga ttcaccccgt tggagggcgc gatgatggcg acccgttccg gttcggtcga
    19441 tcccggtctg ctcgtgcatc tgttggagca gaagatctgt cgtgttgacg agttgagcga
    19501 tctgctctac caccagtccg gtctggccgg gatgacaggc accagcggcg atatgcggga
    19561 cgtgctcgct gcgcgcaagt gcggggacca ggacgcggcg ttggcggtag aggtttacgt
    19621 gcgccgtatt cgcagggaga tcggtgcgtt ggcggtgtcg ctcgaccggt tggacgcggt
    19681 tgtgttcacc ggcggggtgg cggttcacaa ctgggagttg gtcagggaga tcgcccaggg
    19741 gcttgaggtt ctcaatgtcg atgtggtgaa gcggttgttg gccgcgcacg gcgatcgggt
    19801 ggtcagtccg ctgggtcagt tgccgcgcgt cttcatgatc aaggatcggg aagagcttga
    19861 actggccaag caggccgagt tgacgatggt tcggatcgag cagggagtga cgtcatgacg
    19921 tgtccgcaat tgcgtgccgc gcttgaggcg gcagtcctcg cgccatcccc acacaacaca
    19981 cagccgtggc gcttcgaggt cacggacggc caggtggatg tgttgctgga cgagtcccgg
    20041 attctggcgg ttgccgatcc ggatggcagg gaggcgcgga tgtcctgcgg cgccgcgttg
    20101 ttcaacgtac gcatgtcgct gcgcgcgcaa gggctgccgg ttcatgtgaa ccttctgccc
    20161 gtgccgtacc ggccgcacct gctggcacga gtgaaggtca gtggacacct tgccgccaag
    20221 actgacgaac tggtgctgca cagggcaatt cctcatcggc acaccaaccg gcggccgttc
    20281 cgtgatgatc ctgtacccgg gtccgtccgg aagatcctgc ggcaaggggc gttgcaggag
    20341 ggcgctcggc tggtgttgct ggacaagccg gggcgttacc actcggtggc cacgcttctg
    20401 cggctggctg agaacgcgca gcgtcaggat gccgagttcc aggacgagct gcggcggtgg
    20461 gttgccaccg acctcaccag gctcgacggc gttccgcttc tggcaggagg gccgccgcca
    20521 gtgactgagc cgttggtgat actgcgccag tacggttcga acgggacgaa gccaccgcga
    20581 gagtacgagc aggagccgtt gctgggtgtg ctggtgacgc accgggacga ggtacacgac
    20641 cacgtgcgtg cgggtcaggc tctgcagcgg gtcctgctca ccgccacagc ggctacggtc
    20701 agtacgtcat ttctgtcggc ggcggtcgag tcgccgcgga tccgttccgc gctgcgcgat
    20761 ctgctcggtg acgagggata ccctcaggcg gttctgcggt tcggttacgg ctatcagccg
    20821 ccacacactc gccgtcggcc tgtcgagcaa gtgagcaact gccttgagac gccgcattag
    20881 tgcggtgtct caaggcagtt gtctggtgaa cgaatcaata cgggtcaggg gatttcacca
    20941 caagaaccgg gcacggggcc atgtgcagcg cggtggcggt gaccatggag agtttgcctg
    21001 gttggccgcc ggggccgagc acgagcagat cgctgcggtc gcatgtgcgg acggcttcgt
    21061 gtggctgact gcgcaccaga tgcaggctcg ggatcacgtc aggggcgatg tcgcgaacca
    21121 ggtcgtgggc gcgttcgagg atttcggctg ggtcgctgtt cgcaggaacc gtgtgtgcgc
    21181 ccggcaatgg aacggcgtgg atgagtcgta gcctgctgcg ggtgcggact gcgaactgga
    21241 tcgcgcggcg gatgacggcc tcgtcgtcgc gtccgccgag cgcggcggtg atccatcggt
    21301 gctcaccctg taccgagcgt gcttcaccgc ggacgaccac ggcatcgcac tgggcgccgg
    21361 aaatgatggg cacgacggat cgaccgagac cgaacggacc gtgcctgcgg ccgcggtagc
    21421 cgacgatcac caggtcatgg tccttgctgg cggtgatgag ggtatggacc ggcgagtcgg
    21481 gagacacggt gaccgaggca aagagccacc ggtaggcgtc gagccgtcgg gcgatcgcct
    21541 ggtcgtcgga cgattccgag gcgaacacgc gcagccgtgc gttcagcaac gcggcatggc
    21601 gcaaagccca cgtcaacgcc gcgtcgcccc acggcgttcc gtcggttccg acggcgaccc
    21661 gtggccgtcg gactggacgc tgctggggta ccggacggat cgccggtgcg ctgcgggtca
    21721 tcgctcctcc aatgtctgca cgctgaacac ccacagtggt ggcggccggt accgggcgga
    21781 tagggccgcg tgccatgcgg aaaggaggcg aaggtcccga gtcggtcggg gcgcgcggca
    21841 gtatcggcgg agcaggtcac gcgggcagcg ttgtggtcga cgacctcgac ggaaggcaac
    21901 cgatgaccgc ccacacacag cccaccgaaa cccgggcggg caccgacacg atgcgccgcg
    21961 tcgacgcctg gtggcgagcg gccaactacc tgtcagtcgg ccagatctac ctgctggaca
    22021 acccgttgct gcgcgttccg ctgcagcccg accacgtcaa gccgcgcctg ctcgggcact
    22081 gggggaccgt gccgggcatc accatgacct acgcccacct caaccacctg atcatgcgcg
    22141 acgacgtcaa cgcgctcctg gtcaccgggc ccggccacgg cgcggctggt ctgaacgcgg
    22201 ctgcctggct ggagggcacc tattcggagc tgtacccgca tgtcacccag gacgaggctg
    22261 ggatgcggga gctgtttcgc cagttctcgt tccccggtgg tgtgcccagc cacgcctcag
    22321 cgcacctgcc cggttcgatc catgaaggcg gcgagttggg ctatgccctc gcacacgcca
    22381 ctggggcggc actggacaac cccgacctga tcgtcgcgtg cgtcatcggc gacggcgagg
    22441 cggaaaccgg tccgctggcc ac
//
