LOCUS       NZ_CDME01000008        24384 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Kibdelosporangium sp. MJ126-NF4, whole genome shotgun sequence.
ACCESSION   NZ_CDME01000008
VERSION     NZ_CDME01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium sp. MJ126-NF4
  ORGANISM  Kibdelosporangium sp. MJ126-NF4
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-NOV-2014) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000826545.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:10:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,648
            CDSs (total)                      :: 10,573
            Genes (coding)                    :: 10,470
            CDSs (with protein)               :: 10,470
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 19 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 5 of 103
            Pseudo Genes (multiple problems)  :: 10 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1423387
            Orig. end                         :: 1447771
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CDME01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24384
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /product="thioamitides"
                     /region_number="9"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /rules="((YcaO or TIGR03604) and TfuA)"
                     /tool="antismash"
     cand_cluster    1..24384
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /detection_rules="((YcaO or TIGR03604) and TfuA)"
                     /kind="chemical_hybrid"
                     /product="azole-containing-RiPP"
                     /product="thioamitides"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..24384
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14384](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14384)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(157..171)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            648..1142
                     /locus_tag="BN1199_RS25685"
     CDS             648..1142
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024212.4"
                     /locus_tag="BN1199_RS25685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_042187438.1"
                     /transl_table=11
                     /translation="MIELDWLTEDEQRVYREFSTMSRELFNHFDCDLKNDVGVSRTYYE
                     ILFVLGRAPDNRLRLTDLATGTRSAPSRITHAVGKLVREGLIHRRANPADGRGWTVELT
                     DLGVETLKAAAIRHAQSVRTYLLDPLTDRQRDELRRISEKVTTRIADVTSSGERTDSHS
                     C"
     gene            1169..2569
                     /locus_tag="BN1199_RS25690"
     CDS             1169..2569
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="BN1199_RS25690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_083466707.1"
                     /transl_table=11
                     /translation="MMDKTDPDVVLDPGSPAADRTGSRRLGFVGVLLGVFMIVLDTTIV
                     NVAVPRIQDDLSGTVTGMQWVVNGYNLLFAVLLLSSGAASDRHGGRKLYALGLVLFAAA
                     SLACGVAETVPVLIAARAAQGVGSAMMLPTALALAARLFPEPAERGRAFGQWAAVAGAA
                     TVLGPLVGGVLVDTLGWRAIFFVNIPVAIAALWLLLCHTPETPTHRHRFDLAGQGLGVI
                     VLAAAAIALTEAGRSGWGEAVVLAGVGIAGIAAGVMVVVERRVRAPMIPPALIGSRQFA
                     ATSVIGLILSIGIYGQMFVLSLYLQDQRGLSAWVTGLAFLPFAAVTVVGPLVASKFLGR
                     DKVRDTLLVGMIAGAVASLVLAFAGAQTPYPVVAIGLVLLGICQSAAQPAIASSALIGA
                     PKQHTGVASGVLTAARQVGSVLGVALLGGLVGHDFEPGMHLALLIVATLFGIGALVTIS
                     FVKTHKKA"
     protocluster    1923..24384
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[11922:14384](-)"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(11923..14384)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="2"
     gene            complement(2554..2688)
                     /locus_tag="BN1199_RS58635"
     CDS             complement(2554..2688)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS58635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_255356848.1"
                     /transl_table=11
                     /translation="MLAMVRQAAADVYAGLPHGLAIVDPRPVHAETVQRGSAVGQAFL"
     gene            complement(2749..3528)
                     /locus_tag="BN1199_RS25695"
     CDS             complement(2749..3528)
                     /EC_number="1.-.-.-"
                     /EC_number="1.6.99.-"
                     /GO_function="GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667208.1"
                     /locus_tag="BN1199_RS25695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_042187440.1"
                     /transl_table=11
                     /translation="MKTLIVHAHPESKSLNGSLKDLAVSTLEATGHEVRVSDLYAMDWK
                     AVVDAADYGPDASSPLKVVSDSGRAFDAGTLGADVRAEQAKLVWADMIVFQFPLWWYSM
                     PAILKGWVDRVFTHHFAYGVGEHSDTRYGERFGEGTLAGRKALLSVTVGGPESHYAARG
                     INGPIDDLLFPIQHGILYYPGIEVLPPFVLYSADRLTGEDYPDVAKAWEQRLLTLETTE
                     PIAFRRQNFGDYEIPALHLKEGLEPVGRTGFGLHVRG"
     gene            3667..4257
                     /locus_tag="BN1199_RS25700"
     CDS             3667..4257
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="BN1199_RS25700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_198151681.1"
                     /transl_table=11
                     /translation="MDDLAGFLRTRRSRVDPAAVDIPADTRRRVEGLRREEVAHLSGVS
                     VDYYVRLEQGRATQPSEQILDALARVLGLDETEHEHLYRLARQRRRRAKTPGGRIRPEL
                     LRVLDLVADAPALIMDHRMDVLAGNRLAELLYGRPMPGLNTAQHIFLDETERGLYTNWE
                     QCTRDVVGHLRPGELRTTGRIRHGAAGVVRRPR"
     gene            complement(4360..4869)
                     /locus_tag="BN1199_RS25705"
     CDS             complement(4360..4869)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020668792.1"
                     /locus_tag="BN1199_RS25705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_042187442.1"
                     /transl_table=11
                     /translation="MTGWAADEEFAGVTPQLTVADTDAAVRFYTAVFDADELLRNHAPD
                     GRVMHCELLVGGGRLLLHDEFPEHGAGRGPVALGGTPVVLHLYVADVDAVFAAALAQGA
                     TELIAPQEAFWGDRYAMIKDPFGHHWSVAQRVADPSVAELQERADRWAEDNSGASPNDT
                     AAERRD"
     misc_feature    complement(4854..4869)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.73"
                     /tool="antismash"
     gene            complement(4870..5220)
                     /locus_tag="BN1199_RS25710"
     CDS             complement(4870..5220)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229671.1"
                     /locus_tag="BN1199_RS25710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_042187444.1"
                     /transl_table=11
                     /translation="MPPLTPAAFAVLLALTEGEQHGYRLVADVERLTGGTLVLGPGTLY
                     RTLQRLRVDGMVEEIGTDEEAVRADRRAERRRSYRITPAGSRAVRGEARRLASLLTSDT
                     AQAVLRSDERGE"
     gene            5347..6558
                     /locus_tag="BN1199_RS25715"
     CDS             5347..6558
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036297 - interstrand cross-link repair
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632670.1"
                     /locus_tag="BN1199_RS25715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA glycosylase AlkZ-like family protein"
                     /protein_id="WP_042187446.1"
                     /transl_table=11
                     /translation="MTTEISLDKLRAWWSHRQGLDGSLAGSSPEAVLSRTGWARSVGGC
                     SPYLGFFARAGLDREVVDKAVANLDVHELPSARGCTYILPKEDFALGLTVGAGAPEGEL
                     AVASKHLGVTTKEINRLCDSVVSALEAASEPLDAAGLRTVVGDEVRNLGAEGKKRGQTT
                     TLPLALGLLQSHGRIRRVPANGRLDQQRFGYVPWTPSPLDGDRQDVDARRTELAGRYFS
                     WAAPASLKHFRWFSGLSSAAAKKAIEPLDLRPVGDTDLLLPADLTGEFEKFTVPRKPVY
                     ALVAGIDGIHLLHRELSRLVNPEDAERHSPGDKPGRTVSDETDPQCPIIVDRGRIVGLW
                     EYDVDATEIVCQTFVKPDAALKKAIADVQSYVRDQLGDARMTSLDSPKSRAPRIADLRT
                     GPGF"
     gene            6624..7517
                     /locus_tag="BN1199_RS25720"
     CDS             6624..7517
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015411.4"
                     /locus_tag="BN1199_RS25720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_157528327.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 7.8e-10, bitscore:
                     34.8, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVGVVGVGRIGRPMVARLVAAGFEVVATDVRSECRHMTEEAGAR
                     WASDASQVTPGSSVVLTVLPGSPELQELVLGSDRLLSAMEDGVVWVDLTSASFELGQEC
                     AHRARMQGVAYLDSPVGGGVPAMREGTVTLYVGGDVDVLERTTPVLRSFAKTIHHVGDH
                     GMGYLTKLLINLLWFGHATLTTEALLLAQRHGQAPHRMREVLLGSAGDSAFVTHHLPAL
                     LDGNYLNDFGLDRCVEELESIEHSADRAGTPHPLTSVVADLHRLALQHYGAVDGELMAS
                     AWLEEQAGARLHSEES"
     gene            complement(7559..8827)
                     /locus_tag="BN1199_RS25725"
     CDS             complement(7559..8827)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005458283.1"
                     /locus_tag="BN1199_RS25725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_042187449.1"
                     /transl_table=11
                     /translation="MSLLRHRDFRLLWASDTVSQFSTFVAQTVMPLLAATALMATPFEM
                     GLLTAAETAAFLLIGLPAGAWVDRMRRRPLMVGANVVRTVLLLSIPMAWWTGLLTLSQM
                     IVVALVAGVCAVFFDVSYQSYLPTLVGREQLLEGNAKLQTSQSAAQVTGPALGGVLTQL
                     VGAATAISVLGLGYAASALSLLRITRPEPKSASVPAHRLRAEIGEGLRFVYGNPIIRAI
                     ALTGGTVGFFQMMETASMVLFLTRDLGLSSSQVGLVLAAGGIGGGIGAATSGRWYRRIG
                     HAKAMWVPIVLLAPFELLIPLAQPGWRIWLVVVGIVGVNYLMIVQNVAQVSFRQSVCPD
                     RLLGRMNASMRFVMWGVFPFGALAGGTLGELIGVRGTLWVAACGLSVSGVWLMLSPLRT
                     IKHTTDAHHDLEARPTRDTAASR"
     gene            complement(8832..9989)
                     /locus_tag="BN1199_RS25730"
     CDS             complement(8832..9989)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016712 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, reduced flavin or flavoprotein as one
                     donor, and incorporation of one atom of oxygen [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="BN1199_RS25730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_042187451.1"
                     /sec_met_domain="p450 (E-value: 4.3e-23, bitscore: 78.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQAIPYPQDRTCPYHPPKAYDPLRAGDAPHQVTLYNGQKAWVVA
                     KHAAARALLIDKRLSADRRRAGFPITAPRLEIGRSTTPSFLTMDGDEHARHRRMFIAEF
                     AVKRVNELRPQIESIAHETLDKVLAKGSPADLIADFAVVVPTTVICGILGVPYRDREFF
                     QAAADVFVRDSSLAEIQRATNDLNEYLTTLAVDPPMDGLIARLASAGELTPAEIAIDCR
                     TLLFAGQETTASTMGLAVIALLEHPQQLAALRAGQNVVEEVLRFVAVLDGGVLRIALED
                     IEIGGVLIRAGDGVLVSTSLASRDPDVFTDPDTFDVGRTGRNHVAFGYGIHQCIGQNLA
                     RVELDVALSALFERIPALRLAVPTAELELRGGAAIQGVHSLPIAW"
     gene            complement(10001..11926)
                     /locus_tag="BN1199_RS25735"
     CDS             complement(10001..11926)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="BN1199_RS25735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="WP_042187453.1"
                     /sec_met_domain="PF04055 (E-value: 8.2e-12, bitscore: 42.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSREASVWLLLPPLIETNFGNPYPSTAVLSSFLEQNGVATAQD
                     DLNEDFALFLLEPQLLTKLAGGEFEGVSADSHPAACARWALRYRADLFDEQGRHYFNSK
                     HSQNNAALVGLARPFLIDPDREAIENVDTAPIAEVYRTFYDRVDLAGRWPDGTRLVGIS
                     VPMGPELIPALILAELLKKIQPDVRIVLGGPTISLMEPEDIEHLLSSNPAVDCVVRFDG
                     EFPLLELSRQVLDEHWQPGTSAGVSSHVGAKVKHTPPGVGPNLNVLPPPIYPENILGRL
                     VDPLVPISQARGCYWGKCDYCDFVELFDGSPAFRGRHVVGFVDEIAHHIAVNNARRFAF
                     ITESLPPAFARRACQLIVDRGMDIAWHSFVMVDRRFDSELLELMVRSGCDHLVIGMETM
                     TTRVLKLVHKSADREENIRFLKEAKQAGIRLNVNLIPNLPSTTYDEAMRSLEDVQALSD
                     GIERIAVFPFEVTKSSGVGRAPDQFGLQVQNGMDEKGIFQYGLNHVAISDPAMTDNERA
                     EVFRRFREFAAEVNSRSTSAFDEHLPDSTSVLRIAIKNMDIRVLNGDLACTHIKTQRTF
                     RLGRSLAAILRPYLDGGRFTLAELRQRIGTDSADVLVKSLQRARVLELASMPSGDELAE
                     RVHSRV"
     gene            complement(11923..13242)
                     /locus_tag="BN1199_RS53055"
     CDS             complement(11923..13242)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF019429.4"
                     /locus_tag="BN1199_RS53055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TfuA-like protein"
                     /protein_id="WP_052478399.1"
                     /sec_met_domain="TfuA (E-value: 8.5e-45, bitscore: 147.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQTIVFLGPSVRPDLRSRYARRFQIRPPVAAGDLLTLRLRAGDV
                     VGIVDGYFRTRPAVRHKEILHLLESGVAVHGAASMGALRGAELAAFGMVGHGRIFEDYR
                     SGVLVADDEVAVLHATSAEEYAPLTEALVNVRYKLEQAVTTAMISRTRADNIISSLKEV
                     PFADRTLEAILAHVDKQCDDRDQRAHIRLLLTNQENQKTDDALTLLEAISRQPTHSRQA
                     VTINRTRHLKIWLAETEGSDDEEAGPIADALVLDYCRVLASDYPAFHQRVGSEQLRRKP
                     LACWDGQDLTGFERWLTNDERRLPKTEQASRVMVRAGFTEQALLFDNPFLDALRSTPAF
                     ERARSGVRDVLVFNKAVQRARPDVSLAYLAEQNITDWFMSRLGQGCGLSDIALQRGYSS
                     AESFVAAARPFYLYDKVKRLSGQFTMLSAVDTSDDKARTR"
     gene            complement(13239..14384)
                     /locus_tag="BN1199_RS25745"
     CDS             complement(13239..14384)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR00702.1"
                     /locus_tag="BN1199_RS25745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YcaO-like family protein"
                     /protein_id="WP_042187455.1"
                     /sec_met_domain="YcaO (E-value: 1.7e-68, bitscore: 228.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASAFASQKTITFGTHRSCPPDVTMRKIEKHFDALGITRVADVT
                     GLDDIGIPVCQAVRPNSRTLSVSQGKGVTLELAMVSAAMESIELWHAEEAEFDEVYASI
                     WEMEDNLSYRVSDLALRKSSTPPPGLRLSWVRATSALGGDATWLPRLCVGLDSTDQTRW
                     VFPLFYVSSNGLASGNTWEEAVVHALCELLERDALARAGHDWRGRRLHLTGLDEGCASL
                     VERFERSDTSVVVRDLSDLVGLPCFEAAVWSRTLPHVFAGAGCHLDAEVALSRALTEAA
                     QSRLTLIAGARDDIAHSIYAWLGTRRKLSDPLLNRPAPTRLFTDVESLATSSFAEDVRV
                     LNSLVRHKTGHSPLVVDLSRPEIGIPVVRVVAPGLQIKDGA"
     gene            complement(14941..16038)
                     /locus_tag="BN1199_RS53060"
     CDS             complement(14941..16038)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS53060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_052478400.1"
                     /transl_table=11
                     /translation="MRCSTTATPSRSPATNAACKFWIGNIKHAATVGMVLARLVVDGQE
                     QGHHWFRVPLRAKENEPPLPGITILSSDPKGGIQAHQVGGARFTGVRLPREALMARYSR
                     IDADGRFSSTLPDANARFVRSIETFVQERVFPLSAGARAAELAAHLTWRFAGHRGDPPV
                     AGPKGSSERTTVPRPAVPGPAALPRASWLVLDVLAACREMCGSQGFHSHNQIVTLRTDF
                     EVNVTFAGDNSVMAYQVARNAARSPAFARPARTLAERVEQDLGELWRGRPDGSFTHDEA
                     VTLVHARMLGLIMSEHDSDPQVPQPIMDDLVADFAVHRLGAVHRPLSAEREKIDFLAEL
                     LAPVPEIVSAPMVDDGYLAAFSRPA"
     gene            16383..17006
                     /locus_tag="BN1199_RS25755"
     CDS             16383..17006
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS25755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_042187457.1"
                     /transl_table=11
                     /translation="MDAEKNTGRRVALGALAAAGATLAGAVTTSRTAEADSTAAGGRKV
                     RETFKVVDKRGQQRFLLSATKPPLIIDGTTIPADRRSGPENGSYFIFNDENGDEKGGLL
                     VSPTGGHIAFDYPHAVDGIRLTLKAENGKGGAGLEIKGVPDPSGGSQAKAVPRAALGAH
                     TAFGAQLMIADSQGRPRIVLQVDEHDQPTIKVLDEQGAVVKQLF"
     gene            complement(17081..17833)
                     /locus_tag="BN1199_RS25760"
     CDS             complement(17081..17833)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672784.1"
                     /locus_tag="BN1199_RS25760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_042187459.1"
                     /transl_table=11
                     /translation="MPRGRLTPQDRQCIATGLAAGRGYADIARSLGRPTSTVTREVARN
                     GGPTGYRAGDAQRASVRRARRPKGVPSPMAADPYGRTPEAVADAFAELTAVLTQTGLPQ
                     MAASVFACLYATDTGSLTAAELVQRLQVSPASVSKAVSYLETQELIRREHDTAGRRERY
                     IVGGDLWYRSLMATAQRNTALAAGARRTATLLGSDTPAGARLADAAEFLDRIGQEIIQT
                     LQRWWQAHLADSSSTASTDFRSVTQTLG"
     misc_feature    17865..17883
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.43"
                     /tool="antismash"
     gene            18081..19271
                     /locus_tag="BN1199_RS25765"
     CDS             18081..19271
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /locus_tag="BN1199_RS25765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_198151682.1"
                     /transl_table=11
                     /translation="MTTEPVPTGSGRMPRSADPDTSAATGGRSLAPDLARGLMLLLIAL
                     AHVPGFLSSWQSGMPLLDDVVLFVKSLIADNQARAMFVFLFGYGMGQLAYRHHARGGDW
                     AGLRTLLRRRSLWLIIIGFAHTILLVPIDIVAIYGLALLLFTPLVRARDKTLGWTAALT
                     VAPATLLLAWQSVTAQLGAQAGTPVTFAQIMEPTYGAHLLANATKPAQAVIGIVMVLPG
                     MLLGIWAARRRLLDRPAEHRALLRRAAFGLLTLALIGRLPAALLAAGVWDSTAVGVQWM
                     VAVAHDLTGYAGGIGLAAAVGLASARIGDRHGRLSTALAALGQRSLTFYLFQSAVWLAL
                     FYPFTLNLRDQVSLAGSYGIAAVVFAVSVLLAEWMRRTGQRGPMELLLRRMSYPRR"
     gene            19683..22511
                     /locus_tag="BN1199_RS25770"
     CDS             19683..22511
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="BN1199_RS25770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_052478401.1"
                     /transl_table=11
                     /translation="MDFRMLGSLEVGQAGKQVELRGRRQRSLLAGLLLRANLTSSVTYI
                     TDAVWENPPSAPDSNIRTYVTGLRRQLREPGEPSPRLQTRTGGYLLVVHDGELDVAVFE
                     QLADRAGAAMANGDYARAADDLRKALDLWRGEPLEGLNPTPLLHAEVLRLQERRLTVLE
                     QHARAQIELNGHKPLVGELRQLVARHPLREELWALLMLAQSRSGRQADALAAFNEAREH
                     LVRELGIEPGPQLRQLREQIRRGDETVLSSAPSAVALQPRADDARRQLPMDIAEFTGRE
                     PELRALHRLVDKVDADKPASTAVVISTIEGMAGVGKTRLAVRAAHQLVGAGRFAEIQFW
                     TDLRGFSADEPPADPAGVLESLLRALGVHGDEIPQGLDERAALYRTKLSGREALVLLDN
                     AVDADQVRPLLPGSPTCLVLITSRHRLAGLDGAQPLSLDVFSTEEGVALVARIIGAQRV
                     AAEPAAARRVVELCGHLPIAITLAARRLQARPRWTLVDLVGRLDATDQRLNQLSDGSRA
                     VRAAFDLSYQVMPVERQRMFRLLGLHPGQDFAAHSAAALFETTPAHAEALLEDLLDEHL
                     IEQQVPGRYGLHDLLRNYAHDCVRQEDDQCVRHAATERVLGWYLHTAAIAGRLLQPRRE
                     RVTPDSSCAPAHTMRMSSRIEALRWFETERGNLVATVHMASEHGFDRIAWQLPLVLLDF
                     FYLRKYWQDWIATHRIALAAATRLGDQAAQAKVLNGLGVAYSDLGDYSESIECHLQALE
                     IERAAGDLVSQAWNLNNMGVGFTELLRLDEAADHLRESVALHRTTGDQYGEGVALTNLA
                     DACRVAKRLTEATRFLREALGVQQAQGDNAGQHFTLCSMGDVAYDSGQHELAIQYYEKA
                     IAFSRAIGDQWSVAHVLTRLVRPWHTEGRAELVRERAPEALRILEELGATKAGKFRGWL
                     REHGCEPAEGRQ"
     gene            complement(22573..23598)
                     /locus_tag="BN1199_RS25775"
     CDS             complement(22573..23598)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS25775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_052478402.1"
                     /transl_table=11
                     /translation="MIKQLAASAILAVAAAASVACSAASADAPAAQTFPLPTAEADPAE
                     IVTGRDGNIWFTEPGIGKIGKITPAGQVTEYTLPSTAVVVGGLAAAADGNIWFIENPEE
                     EGVAKIAKITPAGQVTEYPAASADAVVTGITAGPDGNVWFSERLAESGAERLAKITPAG
                     QVTEFPLAAPDAIVNALTAGPDGNVWFTETLAESGAGKIARITPAGQVTEYALPAADAS
                     PASITAGPDGNLWFSEGATETDGEKIGRITPAGQVVDFPLPAADAVVNALTAGPDGNVW
                     FTETLAESGVGKVARITPAGQVTEFTMDNPESTPAGVTTGPDQKVWFTDPGTNSIGRIA
                     S"
     gene            complement(23609..24193)
                     /locus_tag="BN1199_RS25780"
     CDS             complement(23609..24193)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS25780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_042187461.1"
                     /transl_table=11
                     /translation="MHDSRKGLRAAGLWISALVCGLLFAAAPASAESIEPAEVEDVTVE
                     DLAPADVEVANIVKLTHGQAVTMLRKVGGFTIVSSGNCSNRANPKCTSLTKVNKTTVQG
                     IIAFRKASKCRIKITGGTETGHATMKYSHWNGYKVDIDDSTCVTKYVKKKFKRSGTCGG
                     GYARWKSPAGNVYCLESKKNHFDITYFKPKA"
     misc_feature    complement(24293..24307)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.0"
                     /tool="antismash"
ORIGIN
        1 tccatggtgg cgtggaagtc gtagggccag cggttgcccg ccgaggagta ccacgggacg
       61 gtccagccca tccgctcccg gaagcgctcg agcttcgcga ccgacgcccg ggagaccagc
      121 gcgaacgtgg tgtcgcgggc gtgcaggtgg gccaggtggc cgacactgtc gaccaggatc
      181 gagcaactgt tgtgtccgtg gtcctgatcc gggccgaaca tgaaatggta gatgatcagc
      241 tggcgccgtc ccccgaacat gtcgagcagg ctcaccgtgc cgtcctcatc tgcgaacagg
      301 tactcctcgg tgacctcgac catgggcagt gactgacgac gcgtggccag cgcgtcccgt
      361 gccctggtca gggccttctc ctcggtcaac aactctgtcc tggcggccag ccactcgtct
      421 cgtgacacca cggcgggaag atccaccggc gcacctcgtc tctgtgcgtt gtctgtcgtc
      481 cacatagtta gatccgcgca accggccgaa ctcatcgact cgggctgtaa gacgggacaa
      541 cgatctcgcc atgtccgccg aacccggacg cggcagttac ttcagtgttg tagtagttgc
      601 gacacgctga tatagttcag tactgaagta actgataccg tgttcctatg atcgagctgg
      661 actggctcac cgaagacgag cagcgggtgt atcgcgagtt ctccacgatg agcagagagc
      721 tgttcaacca cttcgactgc gacctcaaga acgacgtcgg tgtttcccgc acgtactacg
      781 aaatcctgtt cgtgctcggc cgtgcaccgg acaaccgact gcgactgacc gatctggcga
      841 ccggcacccg gtcggcgccg agccggatca cccacgcggt cggcaagttg gtgcgagaag
      901 ggctcatcca ccgtcgggcg aaccccgccg acggacgggg ctggacggtc gaactgaccg
      961 acctgggggt ggaaacgctc aaggcggcgg ccatacggca cgcgcagagc gttcgcacgt
     1021 acctgctcga cccgctcacc gacaggcagc gggacgagct gcggcggatc agcgagaagg
     1081 tgaccactcg gatcgcggac gtgacctcat ccggcgagcg aacggattcg cacagctgtt
     1141 gagccggttc ggcggaaaga gctgaaccat gatggacaag accgacccgg acgttgtgct
     1201 cgatcccggg tcgccggccg cggaccgcac cggttcgcga cggctgggat ttgtcggcgt
     1261 gctgctcgga gtgttcatga tcgtgctgga cacgacgatt gtgaacgtcg ccgtgccacg
     1321 gatccaggac gacctgtccg gcacagtgac cggcatgcag tgggtcgtca acggctacaa
     1381 cctgctgttc gcagtgctgt tgctgtccag cggcgccgcg tccgaccgac acggcggccg
     1441 caagctctac gcactggggc tggtgctgtt cgcggcggca tcgctggcct gcggcgtcgc
     1501 ggaaacggtg cccgtgttga tcgccgcacg cgccgcgcag ggtgtcggta gcgcgatgat
     1561 gctgccgacc gcgctggctc tggccgcccg gctgttccct gaacctgctg aacgcggccg
     1621 cgcgttcggt cagtgggctg ctgtcgcggg cgcggccacc gtgctgggcc cgcttgtcgg
     1681 cggtgtcctg gtggacacgc tgggctggcg ggcgatcttc ttcgtcaaca tcccggtcgc
     1741 gatcgcggct ttgtggctcc tgctgtgcca cacgcccgag accccgaccc accggcaccg
     1801 cttcgacctg gcagggcagg gactgggcgt gatcgtgctc gctgccgcag ccatcgctct
     1861 gaccgaagcg ggccgaagcg gctggggtga ggcggtggtg ctggccggtg tcggcatcgc
     1921 ggggatcgcc gcaggcgtga tggtggtcgt cgagcgtcgc gtccgcgcgc cgatgatccc
     1981 acccgcactc atcgggtcgc gtcagttcgc ggcgacctcg gtgatcggct tgatcctcag
     2041 catcggcatc tacggtcaga tgttcgtgct gtcgctgtat ctgcaggacc agcgtggcct
     2101 cagcgcatgg gtcacgggcc tggcgttctt gccgttcgcc gctgtcaccg tggtcgggcc
     2161 gctggtcgcc agcaagttcc tcggccgcga caaggtccgc gacaccctgc tggtcggcat
     2221 gatcgccggt gcggtggcca gcctggtcct ggccttcgcc ggtgcccaga ccccgtatcc
     2281 ggtggtcgcg atcgggctgg tgctgttggg catctgccag tccgcggcac aacccgccat
     2341 cgcctcgtcg gcactgatcg gcgccccgaa acagcacacg ggcgtggctt ccggcgtgct
     2401 caccgcggca cgacaggtcg gctcggtgct cggcgtcgca ctgctcggcg gcctggtggg
     2461 ccacgacttc gagccgggaa tgcacctcgc cctgctgatc gtggcgacac tgttcggcat
     2521 cggcgcgctg gtcaccatca gcttcgtcaa aactcacaag aaggcctgac cgaccgcgga
     2581 cccacgttgg acggtttcgg cgtgcactgg ccgggggtcg acgatcgcaa ggccgtgggg
     2641 tagtccggcg tagacgtcgg cggcggcctg ccggaccatg gccagcatcg gggatccgtt
     2701 cagctgcggg taccacgcgc tgatgcaggc cgggaacgtc gcctgtggtc agccacgcac
     2761 gtgcagcccg aaacctgtgc ggcccactgg ctccagtcct tctttcaggt gcagtgcggg
     2821 gatctcgtaa tcgccgaagt tctgccgccg gaacgcgatc ggctcggtcg tctccagggt
     2881 gagcaggcgc tgctcccatg ccttggcgac gtccgggtag tcctcgccgg tcaaccggtc
     2941 ggcgctgtac agcacgaacg gcggcagcac ctcgatgccc gggtagtaga ggatgccgtg
     3001 ttgaatcggg aacagcagat cgtcgatggg gccgttgatc ccgcgagcgg cgtaatgcga
     3061 ctccgggccg ccgacagtca ccgacagcaa agctttcctg cccgcgaggg tgccttcgcc
     3121 gaagcgctcg ccgtacctgg tgtcgctgtg ctcgccgacg ccgtacgcga agtggtgggt
     3181 gaacacccgg tccacccagc ctttgaggat cgcgggcatc gagtaccacc acaacgggaa
     3241 ctggaagacg atcatgtcgg cccacaccag cttggcctgc tcggcgcgga cgtccgcgcc
     3301 gagcgtcccg gcgtcgaagg cccggcccga gtccgagacg actttcagcg gactcgaggc
     3361 gtccgggccg tagtccgcgg cgtccacgac cgccttccag tccatcgcgt acagatcgct
     3421 cacccggacc tcgtgcccag tcgcctccaa tgtggacacc gcgaggtcct tcaacgagcc
     3481 gttgagcgac ttcgactccg ggtgggcgtg gacaatcagc gtcttcaaag caactccttc
     3541 ggaccgggag ccttcgatcc tggacgccgc ggcgcccggc gttcaggggc gcctcatcca
     3601 tcggatggga cttcctggca acggcagtac caccttcacg gccacctccg ggctcatact
     3661 gagggcatgg acgatctcgc gggcttcctg cggacccggc gttcccgggt cgaccccgcg
     3721 gccgtcgaca tccccgccga cacccgccgc cgagtcgaag ggctgcgccg tgaagaggtc
     3781 gcgcacctgt ccggagtcag cgtcgactac tacgtacgcc tggagcaggg ccgcgcgacc
     3841 cagccctccg agcagatcct cgacgcgctc gcccgcgtcc tcggcctcga cgagaccgaa
     3901 cacgagcacc tctaccggct cgcccggcag cgccgccgcc gcgccaagac accgggcggg
     3961 cggatccgac cggagctgct gcgcgtcctc gacctggtcg ccgacgcacc cgcgctgatc
     4021 atggaccacc gcatggacgt gctcgccggc aaccgtctcg ccgagctgct ctacggccgg
     4081 ccgatgccgg gcctgaacac cgcccagcac atcttcctcg acgagaccga gcgcggcctc
     4141 tacacgaact gggagcagtg cacccgcgac gtggtcgggc acctgcgccc aggagaactt
     4201 cgcactaccg gacgaatcag gcatggagct gctggtgttg tccgcaggcc ccggtaaccc
     4261 agccgaggac gggctgcgcc tgctcgcagg cctgggcgcg aacggcggcg acccgcatcc
     4321 cacaaggaac gcccaggtcc gcgagtaacc caaacgacgc tagtcgcgcc tctcggcggc
     4381 ggtgtcgttc ggcgaggccc cgctgttgtc ctcggcccac cggtcggccc gctcctgtag
     4441 ctcggcgacc gaggggtcgg ccacgcgctg cgccaccgac cagtgatgcc cgaacgggtc
     4501 cttgatcatc gcgtaccggt cgccccagaa tgcctcctgc ggggctatca gctcggtggc
     4561 cccctgggcc agcgcggcgg cgaacaccgc gtcgacgtcg gccacgtaca ggtgcagcac
     4621 caccggggtg ccgccgagcg cgaccgggcc gcgcccggcg ccgtgctcgg ggaactcgtc
     4681 gtgcagcaga agcctgccgc cgccgaccag caactcgcag tgcatcaccc ggccgtccgg
     4741 ggcgtggttg cgcagcagct cgtcggcatc gaacaccgcg gtgtagaagc ggaccgccgc
     4801 atcggtgtcg gccacggtga gctggggcgt gaccccggcg aactcctcgt ccgctgccca
     4861 gccggtcatc tactcgcctc tctcgtcgga gcgcagaacg gcttgcgccg tatcgcttgt
     4921 gagcaggcta gcgagtcttc tggcttcgcc gcggaccgct cgcgaccctg ccggggtgat
     4981 ccggtagctc cggcggcgct cggcacgacg gtccgcacgg accgcttcct cgtccgtgcc
     5041 gatctcctcg accatgccgt ccacccgcag gcgctgcagg gtgcggtaga gggtgccggg
     5101 gccgaggacc agcgtgccgc cggtgaggcg ctcgacgtcc gcgacgagcc ggtagccgtg
     5161 ctgctcgccc tcggtcagcg cgagcagcac ggcgaaggct gccggggtca gcggtggcat
     5221 ggcctcattc ctggctgatc aggaactcgt gaccgtccag gtttggtgat catgtcatcc
     5281 ttctgggtcg gccggccacg gacaccgaat atatccacgg tggacctaaa atgccatact
     5341 ggcggcatga ccactgagat ctctctcgac aagttgcgcg cgtggtggtc ccatcgccag
     5401 ggactcgacg gctcgctggc cggctcctca ccggaggcgg tactcagccg taccggctgg
     5461 gcccgctcgg tcggcggatg cagcccctac ctggggttct tcgctcgtgc cgggcttgat
     5521 cgcgaagtcg tggacaaggc cgtcgcgaac ctcgacgtgc acgaactgcc ctcagcccgc
     5581 ggctgtacct acatcctgcc gaaagaggac ttcgcgctcg ggctcaccgt gggtgccggt
     5641 gcgccggaag gcgaactcgc ggtggcgagc aagcatctcg gcgtcaccac caaggaaatc
     5701 aaccgactgt gtgacagcgt cgtctcggcg ctcgaagccg cgtcggaacc gctcgacgcc
     5761 gccgggctgc ggaccgtggt cggcgacgag gtgcgcaacc tcggtgctga aggcaagaag
     5821 cgcggccaga ccacaacgct cccgctggca cttggcctgc tccagtcgca cggccggata
     5881 cgccgagtgc cagcgaacgg caggctcgac caacagcgat tcggctacgt accgtggacg
     5941 ccgtctccgc tcgacggcga ccggcaggac gtggacgccc ggcgcacgga actcgccggg
     6001 cggtacttct cctgggccgc gcccgcttca ctgaagcact tccgctggtt ctccgggctc
     6061 agctccgcgg ccgcgaagaa ggcgatcgag ccactggacc tgcggccggt cggcgacacc
     6121 gatctgctgc tgcccgccga cctcaccggc gagttcgaga agttcaccgt gccgcgcaaa
     6181 ccggtctacg cactggtcgc cggaatcgac ggcatccacc tcctacaccg cgaactgagc
     6241 aggctggtga accccgagga cgccgagcgg cactctcccg gcgacaagcc gggacggacc
     6301 gtcagcgacg agaccgaccc gcagtgcccg atcatcgtcg accgcggccg catcgtggga
     6361 ctctgggagt acgacgtcga cgcgaccgaa atcgtctgcc agacgttcgt caaacccgac
     6421 gcggcgctca agaaggcgat cgccgacgtg cagagctacg tccgcgacca gctcggcgac
     6481 gccaggatga ccagcctgga ttccccgaag agccgcgctc cgcgcatcgc ggacctccgg
     6541 acgggccccg ggttctagga gtattggtcc taagtggacg ttcaagtgcc ttgtggcgtg
     6601 agttccggtt cctggaggtg cctgtgcagg tcggtgttgt cggagtcggc cgaattggcc
     6661 gccccatggt ggcgcgcctg gttgcggccg gctttgaggt cgtcgcgacc gacgttcgct
     6721 ccgagtgccg ccatatgacc gaagaggcgg gcgccagatg ggcatcagac gcctcacagg
     6781 tcacgcctgg cagcagcgtc gttctgacgg tgctgccggg gagccctgag ctccaggagc
     6841 tcgtgctcgg atcggatcgg ctgttgtcgg ccatggaaga cggtgtggtc tgggtcgacc
     6901 tgacgagcgc ttcgttcgag ttgggtcagg agtgtgcgca ccgagcgcga atgcagggcg
     6961 ttgcctacct tgattcgcct gtcgggggcg gggtaccagc catgcgggag ggcacggtga
     7021 cactgtatgt gggcggcgac gtcgacgtgt tggagaggac cactcccgtt ctgcggtcgt
     7081 tcgcgaagac cattcaccat gtcggggacc acggcatggg ttacttgacc aagctgctga
     7141 tcaatctcct gtggtttggc catgcgacgc tgaccaccga ggcgctgctg ttggcccaac
     7201 ggcatggaca ggcgccgcat cggatgcgtg aagttctgct gggcagcgcg ggcgacagtg
     7261 cttttgtcac gcatcacctt cctgccttgc tggacggtaa ctatctgaac gacttcgggc
     7321 tggaccggtg tgtcgaggaa ctggagtcca tcgaacacag tgccgaccgt gcgggcacgc
     7381 cccatccact gacatcggtc gtcgctgacc tgcaccgctt ggcgttgcag cactatggcg
     7441 ccgtcgacgg tgaactgatg gcctccgcat ggctggagga gcaagcaggc gcacgattgc
     7501 acagcgaaga gagctgattg cgatcaatgg ggcgacaaga acagagtctg ctgtggactc
     7561 atcgcgacgc cgcagtgtcc cgggtcggcc ttgcttcaag gtcatgatga gcgtccgtgg
     7621 tgtgcttgat cgttcgcaac ggcgacaaca tcagccatac gccggaaacc gagaggccgc
     7681 acgctgcgac ccaaagcgtg ccgcgaacac cgatcagctc gccgagtgtg ccaccggcaa
     7741 gcgctccgaa tggaaacaca ccccacatga cgaaccgcat gctggcgttc atccggccga
     7801 gtagccgatc cgggcagacc gattggcgaa agctcacctg tgcgacattc tgcacgatca
     7861 tgaggtagtt cacgccaaca attcccacga ctaccagcca gatgcgccac ccgggctggg
     7921 ccagtgggat cagcagttcg aacggcgcga gaagcacgat cgggacccac atcgccttgg
     7981 cgtggccgat cctgcggtac caccggccgg aagtagccgc accgatccca ccaccgatcc
     8041 caccggcggc gagcaccaga ccgacctggc tactggacag gccgagatcc ctggtcagga
     8101 acagcaccat cgaagcggtc tccatcatct ggaagaaccc cactgtgccg ccggtcagtg
     8161 cgatcgcccg gatgatcggg ttgccgtaca cgaaccgcag accctcgccg atctcggcgc
     8221 gtagccggtg tgcgggcacg ctggcggatt tcggctccgg ccttgtgatc cgcaacagcg
     8281 agagtgccga agccgcataa ccaagtccca gcaccgaaat cgcggtagcc gcaccaacca
     8341 actgtgtgag cacgccgccc agtgctgggc cggtaacctg cgcggctgac tggctggtct
     8401 gcagcttggc gttgccttcc agcagttgct cgcgaccgac caacgtcggc aggtacgact
     8461 gatatgacac atcgaagaag acagcgcaga caccggcgac cagagcaacg acgatcatct
     8521 gggacaatgt cagcaggccg gtccaccagg ccatggggat gctgagcagc agcaccgtcc
     8581 gtaccacgtt ggctcccacc atcaacgggc gccgacgcat ccggtcgacc cacgctccag
     8641 ccggcaggcc gatcagcagg aacgcggccg tttccgcggc ggtcagcagg cccatctcga
     8701 atggcgtggc catcagcgcg gtcgcggcca gcagtggcat caccgtttgc gcgacgaacg
     8761 tgctgaactg gctgacggtg tcgctcgccc acagcaagcg gaaatcgcgg tggcgcaaca
     8821 gagacattcc gctaccaggc gatcggtagg ctgtgcacgc cctggatcgc cgcgccgcca
     8881 cgcaactcca actcggccgt cggcacagcc agccgcagtg ccgggatccg ttcgaacaac
     8941 gccgacaaag ccacatccag ctctaccctg gccagattct gaccaatgca ctgatggatg
     9001 ccgtagccga acgcgacatg gttccggccc gtccggccga catcaaacgt gtccggatca
     9061 gtgaacacgt cgggatcccg gctcgccagc gaggtggaga ccagcacgcc atcgcccgcg
     9121 cggatcagca cgccaccgat ctcgatgtcc tcaagcgcaa ttctcagtac tccaccgtca
     9181 agcacagcaa cgaaacgcaa aacctcttcg acgacattct ggccggcccg aagggcagcc
     9241 aactgctgcg ggtgctccaa caaggcgatg accgcgagcc ccatcgtgga tgcggtagtc
     9301 tcctgcccgg cgaaaagcag ggtgcggcag tcgatggcga tctctgccgg ggtgagttcg
     9361 cccgcactgg ccagcctcgc gatcagccca tccatcggcg ggtcgacggc cagcgtggtc
     9421 aggtactcgt tgaggtcatt ggtcgcccgc tggatctcgg cgagcgaact gtccctgacg
     9481 aacacgtcgg cagcggcctg gaagaactcg cggtcccggt aggggacccc gaggatcccg
     9541 cagatcaccg tggtcggcac caccacggcg aagtccgcga tcaggtccgc aggcgacccc
     9601 ttggccagca ccttgtccag cgtctcgtgc gcgatgctct cgatctgcgg gcgcagttcg
     9661 ttgactcgct tgacagcgaa ctccgcaatg aacatccgac ggtgccgggc gtgctcatcg
     9721 ccgtccatgg tgagaaacga cggtgtcgtg ctgcggccga tctccagtct cggcgcggta
     9781 atcggaaagc ccgcgcgcct gcggtcggcc gaaaggcgct tgtcgatcaa cagcgcccgg
     9841 gcggcagcat gcttggcgac cacccatgcc ttctggccgt tgtacagagt cacttggtgt
     9901 ggcgcgtcgc ccgcacgcaa cgggtcgtag gccttcggcg ggtggtacgg gcaggtccgg
     9961 tcctgcggat acggtatggc ctggctcatc ggttcctcat tcagacccgc gaatggacgc
    10021 gctcggcgag ctcatcaccg gacggcatcg atgccaactc cagcacgcgg gcccgctgca
    10081 ggcttttaac cagaacgtcc gcgctgtctg tccctatgcg ttgccgcagt tcagcgaggg
    10141 tgaatcggcc gccatccaag taggggcgca gaatggcagc caatgaccgg ccaaggcgga
    10201 acgtacgctg ggttttgatg tgtgtgcagg cgagatcacc attcaacaca cggatgtcca
    10261 tgttcttgat cgcgatccgc agcacgctcg tactgtctgg caggtgctcg tcgaacgcac
    10321 tggtcgagcg actgttgacc tcggcggcga actcgcgaaa ccgccgaaag acctcggccc
    10381 gctcgttatc ggtcatcgcc gggtcgctga tggccacatg gttcaggccg tactggaaga
    10441 ttcccttctc atccatgccg ttctgtacct gaaggccgaa ctggtcgggt gctcgtccca
    10501 caccagacga cttggtcact tcgaacggga acacggcgat gcgctcgatg ccgtcggaga
    10561 gagcctggac gtcctccaac gaccgcatgg cttcgtcgta tgtggtggac ggcaggttgg
    10621 ggatcaggtt cacgttcagc ctgattcccg cttgttttgc ctccttgagg aatcggatgt
    10681 tctcctccct gtctgctgat ttatggacca gtttcagtac ccgagtggtc attgtctcca
    10741 taccgatgac caggtggtca catccggagc ggaccatgag ttcgagcagc tcactgtcaa
    10801 acctgcggtc gaccatgaca aaggagtgcc atgcgatatc catgccacga tcgacgatga
    10861 gctgacaggc tcggcgcgca aaggcgggcg gcagggattc cgtgatgaat gcgaagcgcc
    10921 gcgcgttgtt gacggcgatg tggtgagcga tctcgtcgac gaatcccacg acgtgccgtc
    10981 cccggaaagc cggacttccg tcgaagagct caacgaagtc gcagtaatcg catttgcccc
    11041 agtaacatcc gcgtgcctgc gagataggca ccagcggatc gaccagtctg ccgagaatgt
    11101 tttccgggta gatcggtggc ggcagaacgt tcagattcgg tccgactccc ggcggagtgt
    11161 gcttgacctt cgcaccgaca tgggagctga cgccggctga cgtgcctggc tgccagtgct
    11221 cgtcgagcac ttggcggctc agctccagaa gtgggaactc accgtcgaat cgaaccacac
    11281 aatcgactgc ggggttgctg gacaacaaat gctcgatgtc ctccggctcc atcagactta
    11341 tcgtcggacc gccaaggacg atacgaacat ccggctggat ctttttcagc agttcggcga
    11401 gtatgagtgc cgggatcaac tcgggaccca tcggcacgct gatgccgacc agtcgagtac
    11461 cgtcaggcca tcgcccagcc aggtcgaccc ggtcgtagaa cgttcgatac acctccgcga
    11521 tcggcgccgt gtccacattc tcaatcgcct cgcgatcggg gtcgatcagg aacgggcggg
    11581 ccagtccgac gagtgcggcg ttgttctgag aatgcttgga gttgaaatag tgccgaccct
    11641 gttcgtcgaa aagatccgca cggtaccgca gcgcccaccg tgcacacgcc gccgggtgtg
    11701 aatcagctga gactccctcg aattcaccac ccgccaactt tgtcagcagt tgcggctcga
    11761 gcaggaacag ggcgaaatcc tcattgaggt cgtcctgtgc ggttgctacg ccgttctgtt
    11821 ccaagaagga gctcaagacc gcggtagatg gatagggatt gccgaagttg gtctcgatga
    11881 gtggcggtag cagcagccaa acgctcgcct ctcgcgatgt ggtcatcgtg tcctcgcttt
    11941 gtcatcgctt gtgtcaacgg ccgagagcat ggtgaattgg ccactgagcc gtttcacctt
    12001 gtcgtaaagg taaaatggtc gtgccgccgc aacgaaactt tcagctgatg agtagccacg
    12061 ttggagtgcg atatcggaaa ggccacaccc ctgaccaaga cgactcataa accagtcggt
    12121 aatattttgt tccgcaagat acgccagact gacatcgggt cgcgcacgct ggaccgcctt
    12181 gttgaaaacc agcacgtctc gaacccctga ccgagctcgc tcgaaagcag gggttgaccg
    12241 cagcgcatca agaaaggggt tgtcgaaaag gagggcctgt tcggtaaagc cagcccgcac
    12301 catgaccctg ctcgcctgtt cggtcttcgg aagacgccgt tcatcgttgg tgagccagcg
    12361 ttcgaagccc gtcagatcct gaccatccca gcaggcaagt ggcttacgtc gtagctgctc
    12421 tgacccgacc cgttgatgga atgccggata gtcggaggcg agcacacgac agtagtcgag
    12481 caccagggca tctgcgatgg gcccggcctc ttcgtcgtcg gatccctcag tttccgccaa
    12541 ccagatcttg aggtgccgag ttcgattgat ggtcacggcc tgccgactgt gcgttggttg
    12601 tcgacttatc gcttcgagta gcgtcagcgc atcgtccgtc ttctggtttt cctggttcgt
    12661 cagcagtagc cgaatgtgcg cgcgttggtc acgatcgtcg cactgcttgt cgacatgcgc
    12721 gaggatcgcc tccagcgttc gatcagcgaa aggtacttct ttgagggacg atatgatgtt
    12781 gtccgctcga gtgcgcgaaa tcatcgctgt ggtaacggcc tgctcgagtt tgtaccgcac
    12841 gttgacaagc gcctctgtga gcggtgcgta ttcctcagct gaggtggcat gcagaacagc
    12901 gacctcgtcg tcggcaacca gtacacccga ccggtagtcc tcgaagatcc tgccgtgtcc
    12961 caccatgccg aaggccgcga gttccgctcc gcgcaatgcg cccatgctgg ccgcaccatg
    13021 cacggccaca ccggactcca gcagatgaag aatctctttg tgccgcactg cggggcgggt
    13081 ccggaaatag ccatcaacaa tgccgaccac gtcgccggca cgcagcctca gggtgagcag
    13141 gtcaccagcg gcgacgggcg gcctgatctg gaatcgtcgc gcgtaacgag atcggaggtc
    13201 gggccgcacg gatggtccga ggaagacgat ggtctggttc atgccccgtc ctttatctgc
    13261 aggccaggtg ccaccacccg gacgaccggt atcccgatct cgggtctcga caggtcgaca
    13321 accagaggcg aatgtccggt cttgtgacgc accaacgagt tcagcacccg cacgtcctcg
    13381 gcgaacgacg acgtggccaa ggattcgaca tcagtgaaca gccgggttgg cgccggccgg
    13441 ttgagcagcg gatcactcaa cttgcggcgg gtccccagcc acgcgtagat cgagtgggca
    13501 atgtcgtccc tggcaccggc gatcagcgtc agcctggact gtgcggcctc ggtaagcgcg
    13561 cggctgagtg ccacctccgc atcaaggtga cagcctgcgc cggcgaagac gtgcggaagc
    13621 gttcgcgacc agacagctgc ctcgaaacag ggaagcccga ccaggtcgct cagatctcgt
    13681 acgaccacgc tggtgtcgga gcgctcgaat cgctcaacga gactcgcaca accttcgtcc
    13741 agcccggtga ggtgaagccg gcggccccgc cagtcgtgcc ccgcacgtgc cagcgcatcc
    13801 cgttccagca actcgcacaa cgcgtgcaca actgcttctt cccaggtgtt tccactggca
    13861 agaccgttgg aactgacgta gaacaaaggg aagacccagc gagtctgatc agtggagtcc
    13921 aagccaacgc acagccgcgg gagccaggtc gcgtcgccgc caagcgcaga tgtggctcgc
    13981 acccacgaca gccgcagccc aggtggtggt gtgctgcttt ttcgtagcgc cagatcggaa
    14041 acgcggtagg acaagttgtc ctccatctcc cagatggagg catagacctc gtcgaactcc
    14101 gcttcctccg cgtgccacag ctcgatgctc tccatcgccg cggagaccat ggcgagttcg
    14161 agggtgacgc ccttgccctg agagactgac aatgtccggg agttcggacg caccgcctga
    14221 cacactggaa tgccaatgtc gtcgaggccg gtcacatcgg cgaccctggt tattcccagt
    14281 gcatcgaagt gtttttcgat cttacgcatg gtcacatccg gtggacagga ccgatgggta
    14341 ccgaacgtga tcgtcttctg actggcgaat gcgcttgcgc tcatggcggc ttccttttca
    14401 ggggcaggtg cgcccggaac cggataagct tccggacgca ccctgccatt tcgcctgact
    14461 cagtcgtgca gcgtgaacgt gccctcgggc tccgcggcca tctcggccgt gtcgaggtca
    14521 ctcgcgagca ggcgcagatc ctgctgaatc tggtccattg ttcctccttg atacgagagg
    14581 gtattgagac agatttactc gacaccaagt atgtgcacat accgggtagg tcgagatgcg
    14641 taaatccgcc tgccattgac cgccaccctg tgcacacaaa gaagccggat agacggcgga
    14701 caaaatataa cgatcgtgac tttatcggtc tcgaaaggag gcggtcaacc ggccaacccg
    14761 ggaagaattc gggagaaagg cccgcgccgt ataggagcgt acccccttgc atgcgtacca
    14821 gcttgactgt cataatctgg cccctgtcac tcgctgatca tgtccataat ggagcccagg
    14881 cgcgaaccgg gtgcagagca tgaattgagg ggaagaccgc ggcttcatga ctacgtcccg
    14941 tcaagccggg cggctgaacg ccgccaggta cccgtcatcg accatggggg cggagacgat
    15001 ttcgggtacc ggcgcgagca actccgccag aaagtcgatc ttctcccgtt cggccgacag
    15061 cgggcggtga actgccccca gccggtggac ggcgaaatcg gctaccagat cgtccatgat
    15121 cggctgcggc acctgtgggt cggagtcgtg ctcactcatg atgaggccga gcatgcgtgc
    15181 gtgaacgagc gtgaccgcct catcgtgggt gaacgagccg tccggccgcc cccgccacag
    15241 ctcgcccaga tcctgctcga cccgctcagc cagtgtccgg gcaggacgtg cgaacgcggg
    15301 tgaacgcgca gcattgcgtg ccacttgata ggccatcacg gagttgtcgc ccgcgaaggt
    15361 cacgttgacc tcgaagtcgg tccgcagggt aacgatctgg ttgtggctgt ggaatccttg
    15421 cgacccacac atttcacggc atgcagccag gacgtccagg accagccagg aagcgcgagg
    15481 cagcgcagca ggaccgggta ctgccggtcg cggaacagtg gttcgttcag aagaaccttt
    15541 cggaccggcg accggcggat ctccgcggtg tccggcgaac cgccacgtga ggtgggccgc
    15601 gagttcggcg gcccgtgctc cggcgctgag cgggaaaacc cgctcctgga cgaaggtctc
    15661 gatggacctc acgaagcggg cgttggcgtc agggagggtg ctggagaaac gcccgtccgc
    15721 gtcgatccgc gagtaccgcg ccatcagcgc ttcgcgcggg agccggaccc cggtgaagcg
    15781 ggcgccaccg acctggtggg cttggatgcc gcctttcggg tcggacgaaa gaatcgtgat
    15841 gcccggaagc ggtggctcgt tctccttggc gcgcagcggt acccggaacc agtggtggcc
    15901 ttgctcctgg ccgtcgacga cgaggcgggc caggaccata ccgacggttg cggcgtgctt
    15961 gatgttgccg atccagaact tgcaggcggc attggtggcg ggcgacctgc tcggggtcgc
    16021 cgtggttgaa cagcgcactc cccgcaatga gatggtccgt gatggacgat gcccggtccg
    16081 gcaggaccat cattgatcaa gccactcccc agacgacagg gagtgcaggc ctgctccgaa
    16141 cgggcaatgt tcccgactgt ctcgggccgg gggaggagcg tccaatgtgg acatgtcccg
    16201 aaatcgcggt gtcccaaccg gccttgcgga tcagtacttc ccgtccactg cggtgagcag
    16261 caccccactc ggttcagatg ctccgggacg gcagttcttc gcctgtcggc ctttgttgag
    16321 agagttctaa gggctgttct cctacggtgc gctggtcaga tcgccaggac gagggatgtg
    16381 tgatggacgc tgagaagaac acgggccgtc gagtcgcgct gggtgcgctc gccgcggcag
    16441 gtgccacgct cgccggggcg gtcacgacca gccgaaccgc cgaggccgac tcgacggccg
    16501 ccggtggccg gaaagtccgg gagaccttca aggtggtgga caagcgaggg cagcagcgtt
    16561 ttctgctcag tgccaccaag ccacccctca tcatcgacgg aacgacgatc ccggcggatc
    16621 gccgatcagg gccggaaaac gggagttact tcattttcaa tgacgagaac ggcgatgaga
    16681 aaggaggcct gttggtctcg ccgaccggtg ggcacatcgc cttcgactac ccgcatgcgg
    16741 tcgacgggat ccggctcacc ttgaaggcgg agaacggcaa gggaggagcg ggtctggaga
    16801 tcaagggagt gcccgatccc agtggtggca gccaggccaa agcggtcccg cgggccgcgc
    16861 tcggcgcgca caccgccttc ggtgctcagc tgatgatcgc cgactctcaa ggacggcccc
    16921 gtatcgtgct ccaggtcgat gagcacgacc agccgacgat caaggtactc gacgaacagg
    16981 gcgccgtcgt caagcaactg ttctgaccga cgacaccgat gaggccgctc cgtgccgcct
    17041 actgtgggac gaccacccga tgcggccgat acttactcga tcaccccaag gtttgggtaa
    17101 cgcttctgaa gtctgtggag gcggttgacg agctgtccgc gaggtgggcc tgccaccagc
    17161 gctggagggt ctggatgatc tcctggccga tgcggtcgag gaactcggcc gcatcggcca
    17221 gccgggcacc ggccggggtg tcggagccga ggagcgtggc ggtgcggcgg gcgcccgcgg
    17281 ccagcgcggt gttgcgctgg gcggtggcca tcagcgaccg gtaccacaag tcgccgccca
    17341 cgatgtaccg ttcccgtcgg cccgcagtgt catgctcgcg tcggatgagt tcctgcgttt
    17401 ccaggtagct gacggctttg gagactgaag ccgggctgac ctgcagccgc tgcaccagtt
    17461 cggcggcggt gaggctgccg gtatcggtgg cgtacaggca ggcgaacacg ctggccgcca
    17521 tctggggcag accggtctgc gtcagcacgg ccgtgagctc cgcgaaggcg tccgcgactg
    17581 cctccggggt gcgcccgtac gggtctgcgg ccatcggaga cgggacaccc tttggccgac
    17641 gcgcacgccg tacggaggcc cgctgtgcgt ccccggcccg gtagccggtg ggcccgccgt
    17701 tgcgggccac ctcgcgggta accgtcgatg tgggccggcc cagactgcgg gcgatgtcgg
    17761 cgtacccgcg tcccgcggcc agccccgtgg cgatgcactg ccggtcctgt ggggtcagcc
    17821 tgcctcgggg catcgacgct caatctcctg cgactcgcgg tgtccaactg tcgacagtat
    17881 tcccgacaac acgaccatcg caacaccgcc tcgacaacgg agttgcgttc atcgacagcg
    17941 ctaacgcaag aattgcgtcc ttctgagcag ctcatacgcg tcaccggcag tgttccgcgc
    18001 gttgacgaga ttgtaaacgc tacgtagctt tcgcacgacg tgaagagcag gtcaccctcg
    18061 cgaacaggac gacacccgac atgacgaccg aacctgtccc caccggctcc ggccgcatgc
    18121 cgaggtccgc cgatccggac acgtcggcgg ccaccggcgg ccgctcgctg gctccggacc
    18181 tcgcgcgcgg cctgatgctg ttgctcatcg cgctggcgca cgtaccgggg ttcctgagct
    18241 cctggcagtc cgggatgccg ttgctcgacg acgtcgtcct gttcgtcaag tcgctgatcg
    18301 ccgacaacca ggcccgcgcc atgttcgtgt ttctgttcgg ctacggcatg ggtcagctcg
    18361 cctaccggca tcatgcccgt ggcggcgact gggcgggcct acgcaccctg ctgcggcgcc
    18421 gcagcctctg gctcatcatc atcgggttcg cccacaccat cctgctcgtg cccatcgaca
    18481 tcgtcgccat ctacggcctc gccctgctgc tgttcacccc gctggtgcgc gcccgggaca
    18541 agacgctcgg ctggaccgcc gccctgaccg tggcgcccgc gacgctgctg ctggcctggc
    18601 agagcgtgac cgcgcaactc ggcgcgcagg caggcacgcc ggtcaccttc gcgcagatca
    18661 tggagcccac ctacggcgcg cacctgctcg ccaacgcgac caagccggcg caggcggtga
    18721 tcggcatcgt catggtgctg cccggaatgc tgctgggaat ctgggctgcc cgccgacggc
    18781 tcctggaccg cccggccgag caccgggcgc tgctgcgccg cgccgccttc ggcctgctca
    18841 ccttggcact gatcggcagg ctgcccgccg ctctgttggc cgccggggtg tgggacagca
    18901 ccgccgtcgg tgtgcagtgg atggtcgccg tcgcgcacga cctgaccgga tatgccggtg
    18961 gcatcggcct ggccgccgcc gttggcctgg caagcgctcg gatcggggac aggcacggac
    19021 ggctcagcac tgctctggcc gcgctgggcc aacggtcact gacgttctac ttgttccagt
    19081 ccgctgtgtg gctggcgctg ttctacccgt tcaccctgaa cctacgcgac caggtgagtt
    19141 tggccggtag ctatggcatc gccgcggtgg tcttcgccgt ctcggtgctg ctcgccgaat
    19201 ggatgcgccg caccgggcag cgcggaccga tggagctact gctgcgccgg atgtcctacc
    19261 cgcggcggtg acatgtacgg ctgctgaagg ggcaatattt gcggtagcct gccggttgat
    19321 cttttgtagg cggccaattg ggtaaacttc tgcggtatcc cccgctcaac tttggcggta
    19381 tttccagcgc catcccttgc gctggaaacc atagtgcgca tcctcttttc gtctctcgtg
    19441 ctttgatgta ctcggcaggc atcgggtaac aggatgggcg tcgacgacga tcctgctggt
    19501 gatcggtttg tgaagctctg ccgccgaggg gtcgtacgtg tctcactggg gatgtgacgg
    19561 gcgcggctac cgttcggtgc ggctggaaga gatggtggcg gactcgaatt ccgcatatct
    19621 gcgacttgtg cggtgccgga tggactggtc atgtcgatta ctcatgttcg ggggaacaga
    19681 tcatggactt caggatgctc ggttcattgg aggtcggtca ggcggggaaa caggtagaac
    19741 tacgcgggcg ccgtcagcgg agcctgctgg cgggcttgtt gttgcgagcg aatctcacgt
    19801 ccagcgtcac ctacatcacc gacgcggtct gggagaaccc accgagtgcc ccggattcca
    19861 acattcgcac ttacgtcaca ggcctgcgca ggcagctgcg tgaaccgggc gagccgtccc
    19921 cgcggttgca gactcggacg ggtggctacc tgctggtggt tcacgacggc gaacttgacg
    19981 tcgctgtctt cgagcagttg gccgaccgag cgggcgcggc catggcaaat ggcgactacg
    20041 ccagggccgc tgacgacttg cggaaagcgc tggacctgtg gcgtggtgag ccgttggagg
    20101 gcctgaatcc cactccgttg ctgcacgcgg aagtcctacg gctgcaggag aggcggctga
    20161 ctgtcctcga acagcacgcc agagcccaga tcgagctgaa cgggcacaag ccgctggttg
    20221 gcgagctacg gcagttggtc gcgcgccatc cgctgcgtga ggaactgtgg gcgctgctga
    20281 tgctggcgca gagcagatcc ggccgccagg ccgatgcgtt ggctgccttc aacgaagccc
    20341 gagagcacct ggtgcgggag ctgggcatcg aaccaggacc gcaactgcgg caactgcggg
    20401 agcagattcg gcgaggcgat gagacggtgc tttcgtcggc gccatcggcc gtggcactac
    20461 agccgcgcgc cgacgacgcg cgccgccagc tgccgatgga catcgccgag ttcaccggcc
    20521 gagagcccga gcttcgggcg ctgcatcgcc tcgtggacaa ggtcgacgct gacaaaccgg
    20581 ccagcacagc ggtggtgatc tccaccatcg aagggatggc gggagtgggc aagaccagac
    20641 tcgccgtccg agcggctcac cagcttgtcg gcgcgggaag gttcgccgag atccagttct
    20701 ggacggatct gcgtggcttc tctgccgacg agccaccggc cgacccggcc ggtgtcctgg
    20761 aatcgttgct acgcgcactg ggcgttcacg gtgacgagat cccgcaaggc ctggacgaac
    20821 gcgccgcgct ctaccggacg aagctgtccg gccgtgaggc cttggtgctg ctggacaacg
    20881 ccgtggatgc cgaccaggtc cggccactgc tgcccggcag cccgacctgc ctggtgttga
    20941 tcacgagtcg gcatcgcctc gcaggtctgg acggcgcgca gccactgtcg ctggacgtgt
    21001 tctccaccga ggaaggggtc gccctggttg cccggatcat cggtgcgcaa cgcgtcgcgg
    21061 cggaaccagc ggcggcgagg cgggtggtcg aactgtgcgg gcacttgccg atcgcgatca
    21121 ccctggcggc ccgccgactg caagcccgtc cacgatggac gttggtcgat ctcgtcggca
    21181 ggctcgatgc gacggaccaa cggctgaacc aactctccga cggcagcaga gcggtccggg
    21241 ccgcgttcga cctgtcctat caagtgatgc cggtcgagcg gcagcggatg ttccgcctgc
    21301 tgggtctgca tcccggccag gacttcgccg cccactcggc ggcggcgctg ttcgagacaa
    21361 caccggccca tgcggaagcg ctcctggagg atttgctgga cgaacacctc atcgagcaac
    21421 aggtcccagg caggtatgga ttgcacgatc tgcttcggaa ctacgcccac gactgcgtgc
    21481 ggcaagagga cgaccagtgt gtgcggcacg cggcgacgga acgtgtgctc ggctggtacc
    21541 tgcacaccgc cgccatcgcc ggtcgccttc tccagccgcg cagggagcgc gtcaccccgg
    21601 actcgtcctg cgcgcctgcc cacacgatgc ggatgtccag tcgcatcgag gcgttgcgat
    21661 ggttcgagac cgaacgtggc aacctggtcg caactgtgca tatggcctca gaacacggct
    21721 tcgaccgaat tgcctggcaa ctgcccttgg tgctgctgga cttcttctat ctccgcaagt
    21781 actggcagga ctggatagcg acgcaccgga tcgcgctcgc ggcagccact cgtctcggcg
    21841 accaggcggc gcaggccaag gtactgaacg gtctcggtgt cgcatacagc gacctgggtg
    21901 actattcgga gtccatcgaa tgccacctac aggccttgga gatcgaacgc gcggcgggtg
    21961 atctggtcag ccaggcctgg aacctcaaca acatgggagt gggcttcacc gagctcctgc
    22021 gtctggacga agcggcggat catctccggg agtccgtcgc actgcaccgg acgacgggcg
    22081 accagtacgg tgaaggagtg gccttgacca acctggcaga cgcctgccgc gtggcgaaac
    22141 gcctgaccga ggcgacccgc ttcctgcgtg aagcccttgg tgtgcaacaa gcacaaggag
    22201 acaacgcggg ccagcatttc accctgtgca gcatgggcga cgtcgcctat gacagcgggc
    22261 aacacgagct ggcgatccag tactacgaaa aggcgatagc gttcagcaga gcgatcggcg
    22321 accaatggtc ggtggcccac gtgctgactc gtctggtccg cccttggcac accgagggaa
    22381 gggcggaact ggtccgggaa cgagcgccgg aggccctgcg aatcctggag gaactggggg
    22441 cgaccaaggc tgggaagttc cgcggctggc tgcgggagca cggctgcgag cccgcggagg
    22501 ggcggcagta gatacaaggc gggctgtccc acgccgcggc gtgggacagc ccttgatcgc
    22561 gacgctgtga ggtcagctcg cgatccgtcc gatgctgttc gttcccggat cggtgaacca
    22621 caccttctgg tccggcccgg tggtgacccc ggccggggtg gactcgggat tgtccattgt
    22681 gaactcggtg acctgcccgg ccggggtgat cctggcaacc ttgcccaccc cggactcggc
    22741 cagcgtctcg gtgaaccaca cgttcccgtc cggcccggcc gtcagagcgt tgaccaccgc
    22801 gtccgcagca ggcaggggga agtccacaac ctgaccagcc ggagtgatcc tgccgatctt
    22861 ctcaccgtcg gtctccgtgg ctccctcgct gaaccacagg ttgccgtccg gaccggcagt
    22921 gatcgaggcc gggcttgcgt ccgcggcagg cagcgcgtac tcggtgacct gcccggccgg
    22981 tgtgatcctg gcgatcttgc ccgccccgga ctcggccagc gtctcggtga accacacgtt
    23041 cccgtccggc ccggccgtca gagcgttgac aatcgcgtcc ggagccgcca gcgggaactc
    23101 cgtgacctgc ccggccggag tgatcttggc cagccgctcc gctcccgatt cggccaggcg
    23161 ttcgctgaac cagacgttgc catccggccc cgcggtgatc ccggtgacga cggcgtccgc
    23221 cgaggcggcc ggatactcgg tgacctgtcc ggccggagtg atcttggcga tcttggcgac
    23281 gccttcctcc tccgggttct cgatgaacca gatgttgccg tccgcggccg cggccagccc
    23341 accgaccacc accgccgtgg agggcaacgt gtactcggtg acctgcccgg ccggagtgat
    23401 cttgccgatc ttgccgatcc ccggctcggt gaaccagatg ttgccgtcgc gcccggtgac
    23461 gatctccgcc ggatcggctt ccgccgtggg cagcgggaat gtctgggcgg cgggggcgtc
    23521 tgccgatgcc gccgagcagg ccacgctcgc cgccgcggcc accgccagga tggctgatgc
    23581 ggccaactgt ttgatcacag ctctctcctt aagccttcgg cttgaagtag gtgatgtcga
    23641 agtggttctt cttgctctcg aggcagtaga cgtttccggc aggtgacttc cagcgcgcgt
    23701 atccgccgcc gcaggtgccg gaccgcttga acttcttctt gacgtacttg gtgacgcagg
    23761 tgctgtcgtc gatgtccacc ttgtagccgt tccagtggct gtacttcatg gtggcgtgac
    23821 cggtctcggt gccaccggtg atcttgatgc ggcacttgct cgccttgcgg aaagcgatga
    23881 tcccctggac cgtggtcttg ttcaccttcg tcagcgacgt gcacttcgga ttggcgcggt
    23941 tgctgcagtt cccggacgat acaatcgtga aaccgcccac cttgcgcagc atggtgaccg
    24001 cttggccgtg tgtcagcttg actatgttgg ccacttccac gtcggccggt gccaggtcct
    24061 cgacagtgac gtcctcgacc tccgccggtt cgatgctctc cgcgctcgcc ggtgcggcgg
    24121 cgaacaacag gccgcacacc aaggccgaga tccagagtcc ggcggcgcgc agcccctttc
    24181 tggagtcgtg catgctggtt tcctttcgct caaagggatt gaaggacctc gtcctgcgcg
    24241 gacgccacga ccacggcccg gatctccggc cgctttccat ccaggtgcac ggcgaagacg
    24301 acgttcacgg cacgaccttc actgcggccc ggataggtga agatccgcca gcacaggtcc
    24361 cgccacacgt ccagcggctc ggcg
//
