LOCUS       NZ_CDME01000008        21041 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Kibdelosporangium sp. MJ126-NF4, whole genome shotgun sequence.
ACCESSION   NZ_CDME01000008
VERSION     NZ_CDME01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium sp. MJ126-NF4
  ORGANISM  Kibdelosporangium sp. MJ126-NF4
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-NOV-2014) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000826545.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:10:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,648
            CDSs (total)                      :: 10,573
            Genes (coding)                    :: 10,470
            CDSs (with protein)               :: 10,470
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 19 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 5 of 103
            Pseudo Genes (multiple problems)  :: 10 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1252437
            Orig. end                         :: 1273478
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CDME01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21041
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="7"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21041
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21041
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11041](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11041)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(174..185)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    655..670
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.63"
                     /tool="antismash"
     misc_feature    complement(704..716)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(827..1489)
                     /locus_tag="BN1199_RS25020"
     CDS             complement(827..1489)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033343.1"
                     /locus_tag="BN1199_RS25020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_042187255.1"
                     /transl_table=11
                     /translation="MRVLVAEDEEMLADAIAEGLRHMHMAVDVCYDGDAAMERIAVHRY
                     DVVVLDRDLPKVHGDEVCRRIVAGDGETRVLMLTAAASIRDRVDGLGLGADDYMTKPFA
                     FAELVARVHALSRRAHRAVPPVRDREGLRLDPAKRYVERDGQPLSLSPKEFTVLDVLMR
                     SEQGTVVSAEELLEKAWDENADPFTNSVRVTVMNLRRKLGNPPVIHTVPGAGYRFGA"
     misc_feature    complement(1328..1330)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1595..2719
                     /locus_tag="BN1199_RS25025"
     CDS             1595..2719
                     /GO_function="GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021134.4"
                     /locus_tag="BN1199_RS25025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase 87 family protein"
                     /protein_id="WP_052478370.1"
                     /transl_table=11
                     /translation="MRVSLLAGIIAAGVWCALMAHTYRLDLEVYRIGVQAWLDGGDLYG
                     RLPDTSIGLNLPFIYPPVAAALMVPLTVIPFPVATIILTALTIVLVSVTLAITLKSVGL
                     SPRWVALLPAAILLEPVRTTMAYGQINVILMALVVADCLIENPRWRRGVLVGIAAAIKL
                     TPLAFLLFFLIRRDRRAAVTTITSFLGATAVGFVVSWSSSVTFWTDAIFHTEDKVGVGY
                     IANQSILGVLLRLDVGKALWLVLVAVVLAAAVWAMRTATAPMAFGITALAMLLVSPISW
                     SHHWVWCVPVLVIFAAQGQKVLAAVGAVLFAVGPHWWFEQVTTPTLAQQVIVDLYFLFA
                     VAAVAVLAYQAKRGRTVDSLEPTPAGQLTVVQGA"
     gene            2743..3867
                     /locus_tag="BN1199_RS25030"
     CDS             2743..3867
                     /GO_function="GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021134.4"
                     /locus_tag="BN1199_RS25030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase 87 family protein"
                     /protein_id="WP_052478371.1"
                     /transl_table=11
                     /translation="MRVSLLVGIIAGVVWCVWTRHTYGQDLEVYRLGVQAWLGGGDLYG
                     RLPDTSMGISLPFIYPPVSVALMLPLTFVPLSVATIILTTLTIVLVSVTLAVTLKAVGW
                     SPRWLAVLPVAILLEPVWKTVNYGQINVILMALVVADCLVENPRWRRGVLVGIAAAIKL
                     TPLAFLLFFLIRRDRRAALTTVISFLGATAVGFALTWSSSVTFWTDAIFHTDEKVAVGF
                     VANQSTLGVLLRLDIGNGVWLALVAVLLALAVWAMRTATAPIAFSVTALAMLLVSPISW
                     SHHWVWCVPILVIFAAQGHRILAAVGTILFLLGPQRWFELTSQPTILQQALIDSYFLFA
                     VVAIVVLACGTKRWHALDRPPRAADQRLTAVPGT"
     gene            complement(3845..4678)
                     /locus_tag="BN1199_RS25035"
     CDS             complement(3845..4678)
                     /NRPS_PKS="Domain: Abhydrolase_1 (29-262). E-value:
                     1.1e-34. Score: 112.1. Matches aSDomain:
                     nrpspksdomains_BN1199_RS25035_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103952.1"
                     /locus_tag="BN1199_RS25035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_042187256.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-21, bitscore: 74.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.1e-16, bitscore:
                     57.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKHQTEHKTVQVDGTRVFYREAGPKDAPTLLLLHGFPSASHQF
                     RGLIDALKDRFHIVAPDYPGFGHSDAPEAHYTFDFLADVVEKFVQAIGLSRFALYVFDY
                     GAPVGFRLATRHPEWITGLIVQNGNAYEDGLGELAREFIGSRDEAQLRGMLTEQFTRSQ
                     YETGARGPIAPDGWVLDQYFLDRPGRAKIQVDLAFDYHSNVELYPRWQAWLRDHQPRTL
                     VLWGRNDPFFLAAGAERYRDDVPDAEVHLFDTGHFALEEDLDEISPLIVRFLEQP"
     aSDomain        complement(3893..4591)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1199_RS25035_Abhydrolase_1.1"
                     /evalue="1.10E-34"
                     /label="BN1199_RS25035_Abhydrolase_1.1"
                     /locus_tag="BN1199_RS25035"
                     /protein_end="262"
                     /protein_start="29"
                     /score="112.1"
                     /tool="antismash"
                     /translation="PTLLLLHGFPSASHQFRGLIDALKDRFHIVAPDYPGFGHSDAPEA
                     HYTFDFLADVVEKFVQAIGLSRFALYVFDYGAPVGFRLATRHPEWITGLIVQNGNAYED
                     GLGELAREFIGSRDEAQLRGMLTEQFTRSQYETGARGPIAPDGWVLDQYFLDRPGRAKI
                     QVDLAFDYHSNVELYPRWQAWLRDHQPRTLVLWGRNDPFFLAAGAERYRDDVPDAEVHL
                     FDTGHFALEED"
     gene            4748..5278
                     /locus_tag="BN1199_RS25040"
     CDS             4748..5278
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006240677.1"
                     /locus_tag="BN1199_RS25040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_042187258.1"
                     /transl_table=11
                     /translation="MDMVVGEQLAIDLINTRTSEGDLTATADSFARWLKAEDGRLTRPD
                     APDLDAIRQLRTHVAAAVAQARQGLEPPADAVDALNSALRSAPAYRSLAWDGHAMTTAV
                     HRTGDENAQLLAELAEAAAELLTSPSVTEIRSCEGPDCLLIFLPAHPRRRWCSPSLCGN
                     RVRVSRYYQRHKS"
     gene            complement(5498..5869)
                     /locus_tag="BN1199_RS25045"
     CDS             complement(5498..5869)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020661834.1"
                     /locus_tag="BN1199_RS25045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_042187262.1"
                     /transl_table=11
                     /translation="MVSSIHNVALDALDAYGLAQFWSKVYGKPLGDDDKPGDPEVAIDL
                     GGGMNMFFQQVPESKSIKNRMHICLRPDSTRDEEVTRLVTIGATIHDDHRNPDGTGWVV
                     MHDPEGNEFCVERSVAERS"
     gene            complement(5910..6218)
                     /locus_tag="BN1199_RS25050"
     CDS             complement(5910..6218)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS25050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_042187265.1"
                     /transl_table=11
                     /translation="MREVQQKVAQAADKLGLHANAPSLTLTLLSEMGRLSDEVLAATAN
                     GRRPFRPTEGWEQRLADLAFTVINLADQTGVDLATALDGTIARHEANTKPVDDLPGW"
     gene            complement(6229..7335)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="BN1199_RS25055"
     CDS             complement(6229..7335)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666919.1"
                     /locus_tag="BN1199_RS25055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_042187267.1"
                     /transl_table=11
                     /translation="MTLVQLGPPSLRRQSRQVLVGDVPVGGNAPVSVQSMTTTVTSDVD
                     ATLQQIAELTAAGCQIVRVAVPSQDDAEALARIAKSATIPVIADIHFQPKYVFAAIDAG
                     CAAVRVNPGNIRQFDDKVREIASAAAGAGVPIRIGVNAGSLDKRLLEKYGKATPDALVE
                     SALWECSLFEEHGFRDIKISVKHHDPVVMIDAYRKLAARCDYPLHLGVTEAGPRFQGTI
                     KSSVAFGVLLAAGIGDTIRVSLSAPPVEEVKVGAQILESLGLRPRRLEIVSCPSCGRAQ
                     VDVYKLAEEVTAAFEGFPVPLRVAVMGCVVNGPGEAREADLGVSSGNGKGQIFVRGEVI
                     RTVPESKIVETLIEEALSRDWGTTGRDH"
     gene            complement(7332..9050)
                     /locus_tag="BN1199_RS25060"
     CDS             complement(7332..9050)
                     /EC_number="2.2.1.7"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020663204.1"
                     /locus_tag="BN1199_RS25060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_042187269.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.8e-82,
                     bitscore: 273.1, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.3e-06, bitscore:
                     23.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITDHADLASRSTSDLVVLAGEIRDFLVDKVSRTGGHLGPNLGAV
                     ELTIALHRVFHSPDDVLLFDTGHQAYVHKILTGRAADFDSLRQAGGLSGYPSRSESDHD
                     VIENSHASTALSYADGLAKAFSLRESQRRVVAILGDGALTGGMCWEALNNIGGAPKRPM
                     VIVLNDNGRSYAPTIGGIASHLAVLRYEGSSNIFEDMGLAYIGPVDGHDIPDLEHALRR
                     AVRLNRPVVVHCVTRKGKGHPPAEQDEADRLHAVGPAGAVRKPTWTAVFADEITALGAR
                     RDDLVCITAAMAEPAGLAGFAARFPDRLFDVGIAEQHAVTSAAGLALGGMHPVVAVYST
                     FLSRAVDQVLMDVALHRLPVTFVLDRAGVTGPDGPSHHGMWDSSILPVVPGLRLASPRD
                     PARLRELLREAVDVHDGPTVVRYPKAAAGEDIPAVRRTGHCDVLRESPTAQVLLVAVGS
                     LASACLEAADDLVEHGVPVTVVDPRWIAPVDPSLLKLAGRHRLVVAVEDTTTPGALGGR
                     IAQALAANGSDTCAATFALPNRFLPHASRSEILRAHGLDAAGIATTVLKRLEALS"
     gene            complement(9047..9970)
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="BN1199_RS25065"
     CDS             complement(9047..9970)
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010311801.1"
                     /locus_tag="BN1199_RS25065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_042187272.1"
                     /transl_table=11
                     /translation="MQVKVLLASPRSFCAGVDRAIEIVEEVLRRRKPPVYVRKQIVHNK
                     HVVADLQTRGAVFVDELDAVPDGSTVVFSAHGVSPAVRAEAERRALDVVDATCPLVTKV
                     HAEARRFAARGDTVVLVGHAGHEEVEGTLGEAPDQTVLLESPEGVGALDVPDPSNVSYL
                     MQTTLAVDEAAEVVSALRARFPDLKGPASDDICYATTNRQNALTAIAEESDLVLVVGST
                     NSSNSVRLVELAQRHGTPAYLIDDVSEIKAKWLAGVRVVGITAGASAPPGLVDEVVAAL
                     NPISVETRETAKETIQFTLPPSARRS"
     gene            complement(10001..11041)
                     /locus_tag="BN1199_RS25070"
     CDS             complement(10001..11041)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103444.1"
                     /locus_tag="BN1199_RS25070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_042188219.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-62, bitscore:
                     208.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTREVATESRTPREVLAWSRDLVEPASRAAVDTLPGSMRRIAGY
                     HYGWWDEHGRPSDSSGGKALRPTLTLLAAEAVGGDASAVVPAAVAIELVHNFSLLHDDV
                     IDGDVTRRHRPTAWSVFGRSAAILAGDSLVTLAFDVLAASGHPDSVEAMRSLSAAIQAL
                     VDGQSLDVEFEDRRDITLDECVTMARCKTGALISASCSIGALFGGGRATQVDHLWGFGD
                     ELGLAFQLVDDLLGIWGRPESTGKPVYSDLHNRKKSLPVVAALTSHTIAGQELGELYHC
                     DRPLSGTDIERAAELIDLAGGRAWSQEQADDRLARAVRRLRSADPVAAAATELAGLAGL
                     VTHRDH"
     misc_feature    complement(10847..10849)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11046..12401)
                     /locus_tag="BN1199_RS25075"
     CDS             complement(11046..12401)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803727.1"
                     /locus_tag="BN1199_RS25075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_042188221.1"
                     /transl_table=11
                     /translation="MSLGTKAARNLATTTKSVPQMQGITPRWLLRVLPWVQAEGGAYRV
                     NRRLTYAIGDGLVSFTLSEGRVQVVPPELRELALLRSFEDDEALAAIAGRFEQQEFEAG
                     DLIIQKGQTADRLVLMAHGKASKIGLGEYGVEAVLDTLGEGEYFGEQALTGHRNEWSFT
                     VKAKTRCIAMTLSRQEFDRITGQSETLQAHLAELARLRGKASNAKGEAEIELASGLSGE
                     YQLPGTFVDYELKPREYEMSVTQTVLRIHTRVADLYNQPMNQTEQQLRLTVEALRERQE
                     YEMINNRQIGLLHNADLKQRIHTHSGPPTPDDMDELISRRRKTQFILAHPRAIAAFGRE
                     CNSKGIYPNTTELDGKVVQTWRNIPLLPCDKIPISETGRTSILAMRTGEKNQGVIGLHQ
                     TGLPDEYEPGLNVRFMGVDERAIMSYLVSAYYSVAVMVPDALGILESVELGR"
     gene            complement(12689..14104)
                     /locus_tag="BN1199_RS25080"
     CDS             complement(12689..14104)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225101.1"
                     /locus_tag="BN1199_RS25080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_042187273.1"
                     /transl_table=11
                     /translation="MTDTVDSNLDVENGQQQQSLATAAARNLATTTKSVPQMQSITSRW
                     LLRVLPWVQAQGGAYRVNRRLSYTVGDGRIAVTNTGSRVHVVGPDLVELALLRTFDDEE
                     ALNALADRFQQQEYQPGDVIAEFGHEAGHLYVVAHGKVNRIGTGEYGDQTVLSTMVDGD
                     YFGDQALVQDQSIWEFTAKAVTPVTILALPKQSFQELQDQSEALRDHVTAYRDSPKKAQ
                     NVHGEAEINLASGHDGEPELPGTFVDYELSPREYELSVAQTVLRVHTRVADLYNQPMNQ
                     TEQQLRLTIEALRERQEHELINNGDFGLLANADLKQRVPTRSGPPTPDDMDELLATVWK
                     DPSYILAHPKAIAAFGQECNKRGLYPQSIDFNGHQMPSWRGIPVLPCNKIPITDTRTTQ
                     MIAMRVGEQNQGVIGLHQTGLPDEYQPGLSVRFMNINEKAIMSYLVSAYYSAAILVPDA
                     LGVLENVELGRVE"
     misc_feature    complement(14143..14158)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.5"
                     /tool="antismash"
     gene            complement(14449..16281)
                     /gene="cysC"
                     /locus_tag="BN1199_RS25085"
     CDS             complement(14449..16281)
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637153.1"
                     /locus_tag="BN1199_RS25085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_042187275.1"
                     /transl_table=11
                     /translation="MPHLLRLATAGSVDDGKSTLIGRLLFDSKTIFADQLAALERASRD
                     RGEDYPNLALLTDGLRAEREQGITIDVAYRYFATPKRKFIIADTPGHIQYTRNMVTGAS
                     TADLALVLIDARKGVLEQSRRHAFLASLLGIPHIVVCVNKMDLVDWSRERFEEIREEFR
                     RFSMKLAVPDLTFIPVSALLGDNIVHRSTSMPWYEGTSLLHHLEEVHVSSDRNLIDARF
                     PVQYVIRHQDFRGYAGTIAGGVFKPGDEVLVLPSGFTTTVSDILGPGGQPVTEAFPPQA
                     VTLRLADDLDVGRGDLICRPNNRPHVGTDIDAMVCWLTEHGELSPDAQYTVVSTTRSTK
                     AVVTSLDYRLDITTLHRDETAESLSLNEIGRVRLRTRQPLLFDAYRRNRACGSFILVDE
                     TTNNTVAAGMITGPAQSVVWHSTSVQRAERGTSGCTVWLTGLSASGKSTVAVELERRLV
                     ASGRPAYLLDGDNLRHGLNADLGFSAADRAENVRRVGEVARLFADAGVVAVVSLISPYR
                     ADRDLVRAAHDLAGLPFVEVFVDTPIETCEARDPKGMYAKARAGEITGFTGVDDPYEPP
                     LSAELVLHPEQGDPARMAAMILASMDQARLPRMD"
     gene            complement(16281..17192)
                     /gene="cysD"
                     /locus_tag="BN1199_RS25090"
     CDS             complement(16281..17192)
                     /EC_number="2.7.7.4"
                     /GO_function="GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013224713.1"
                     /locus_tag="BN1199_RS25090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="WP_198151670.1"
                     /transl_table=11
                     /translation="MAISYELTNLRALEAESVHVLREVAATFERPVLLFSGGKDSVVML
                     HLAAKAFWPAPPPFPVMHVDTGHNFDEVIEFRDRTVESTGVRLVVSRVQDDIDAGRVVE
                     ETGPRASRNRLQTTALLRAINENRFDAVFGGARRDEEKARAKERVFSFRDEYGQWDPRN
                     QRPELWNVYNGRHRRGEHIRVFPLSNWTELDIWQYIRDEHIDLPSIYYAHRRRVFQRDG
                     MLLAHTRFVTVLPDEDLFEASVRFRTVGDATCTGCVESTAATPDEVVAEVAATRVTERG
                     ATRADDRISEAGMEDRKKEGYF"
     misc_feature    complement(17195..17204)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     gene            17250..17717
                     /locus_tag="BN1199_RS25095"
     CDS             17250..17717
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009079048.1"
                     /locus_tag="BN1199_RS25095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_042187279.1"
                     /transl_table=11
                     /translation="MDDMREVEEIRRLKYRYLRGVDQKRWDLLEAALTEDAVADYGTRA
                     MGEPLVLTGRPAILDFMRQNLDGDKIITFHFTGQPEIDIVGDTATGTWAFEDTVIIKEH
                     RSVIKGAAYYEEEYVRSLEAGWQIKRIFYKRIYEVMVSMDDLPSMRFLAGV"
     gene            17749..18912
                     /locus_tag="BN1199_RS25100"
     CDS             17749..18912
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659116.1"
                     /locus_tag="BN1199_RS25100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_042187281.1"
                     /transl_table=11
                     /translation="MLTESFAAAIADAEKIVAEAPHVLTEQDLTEGYDYLAGNIKASLQ
                     MAWAYDRDYPYFVQSTGPYTKMGLDNPDTLYFHANIRDDAEYVVTGRRGSTADLSFQVL
                     NGDYSPVDVPDSLTAFDDRAFEIAEDGTFEIRFGPGEAGPGYFPLGTGSAMLVVREVYS
                     DWAGEQRGMIRIRRADTTGSAPPAPTKDLMAKRYAVAGRMLTSRLKTFLAFPKWFYLNL
                     PVNTMTEPRSTPGGLTTQFSSVGHYDLADDQVMIITVPVSDAPYHGFQLGSMWYVSLDY
                     INHQTSLTADQARVDPDGRIRYVVSERDPGLANWIERTGHARGYLQIRWQRLSRDLKPE
                     DGPEVEVVPFAELPQRLAFHQEARITPEQYAERIAARQAAVATRMVG"
     gene            18912..19688
                     /locus_tag="BN1199_RS25105"
     CDS             18912..19688
                     /NRPS_PKS="Domain: PKS_KR (6-177). E-value: 1.6e-08. Score:
                     26.6. Matches aSDomain:
                     nrpspksdomains_BN1199_RS25105_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020418700.1"
                     /locus_tag="BN1199_RS25105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_042187284.1"
                     /sec_met_domain="adh_short_C2 (E-value: 4.7e-35, bitscore:
                     118.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLQDKVVVVAGIGPGLGRSIALRCASQGADIVLAARTESRLTEV
                     AKEVTELGRRAVTVPTDISSEADAARLADTAMESFGRVDTLVNNAFAIPPMGDLDGVPF
                     GGIRQGFETNVLGALRLTNLFRPMLEASRGSVVMVSSMVIRHSKPTFGPYKMTKSALLA
                     MAQSLSTELGPKGVRVNTVAPGYIWADNVKYYFDYLAKERGITPQQVYDEVASNIDLRK
                     LPEPDEVADTIVFLASDLASAVTGQCLDVNGGEFHH"
     misc_feature    18918..18920
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        18930..19442
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1199_RS25105_PKS_KR.1"
                     /evalue="1.60E-08"
                     /label="BN1199_RS25105_PKS_KR.1"
                     /locus_tag="BN1199_RS25105"
                     /protein_end="177"
                     /protein_start="6"
                     /score="26.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVVAGIGPGLGRSIALRCASQGADIVLAARTESRLTEVAKEVTE
                     LGRRAVTVPTDISSEADAARLADTAMESFGRVDTLVNNAFAIPPMGDLDGVPFGGIRQG
                     FETNVLGALRLTNLFRPMLEASRGSVVMVSSMVIRHSKPTFGPYKMTKSALLAMAQSLS
                     TELGPKGV"
     gene            19698..20810
                     /locus_tag="BN1199_RS25110"
     CDS             19698..20810
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (extras)
                     Sulfotransfer_3: Sulfotransferase domain"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637145.1"
                     /locus_tag="BN1199_RS25110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfotransferase"
                     /protein_id="WP_042187287.1"
                     /transl_table=11
                     /translation="MDIESLHASATKITGLTDFGDQEYLDGLSVLVDSYHREAGLTEFG
                     LRVQRAGLRSALVARLLSEAAWQRHPEHAAVPIERPIFVTGLPRTGTTALHRLLTEDPA
                     HQGLELWLTDLPQPRPPRETWEENPMYQRIQAGYEQHHVEHPEFMGLHYITADMAEECW
                     RLLRQSMMSVSFECLAYVPTYSEWLAGRDWTAAYHRHRRNLQLIGLPDAGRRWVLKNPS
                     HLFALDALMAAYPDALVIQTHREPRTIIASMCSLAEQATDGWSDVFRGSVIGRTQLDLW
                     ARGLEKFTADRVKHNPAQFYDVQYDEFVADPLGVVTDVYRHFGLALTDGVLDAMNTVHS
                     SGDRRRSHRYDLADFGLTAAQADARFTPGR"
ORIGIN
        1 tgcacggtcc gttcgatgat gcctcgccgc aacgtgacct ggtgcttcgc ggccagatcg
       61 tcgtacgcct ccatcacttc agtggtgagc tggtcgagcc ggaccgggac cttccccggc
      121 aggccgcggt cgctttccgc cagcaccagc agcccctcga tcagacgctc gttgcgttcg
      181 ttgaccagca gcagctgcgc acccagccga ttgacctcct cgtcgtccct ggtcaccatc
      241 gcgacctcga ccagggttcg ctgcaccgcc aacggcgtgc gcaactcgtg agacgcgttg
      301 ctggcgaacc gccgctgtcc ctcgtagccg acgaccacgc ggtcgagcat ctggtccacc
      361 gcaccggcca ggtcacgcag ttcgtcgcgt gctccgcccc ggcggattcg ctgaccgagg
      421 ttctgcggcc ccaactggcg gactgtgccg accatcgcct ggatcgggtg cagggaacgg
      481 gccgccgcga accggaaaac cgcgacgatc agtccaatga ggagcacaag ggcgatggtc
      541 gcgacgatca ggctggtgga gtcggcgtac gttcggcagt attccgagag gcacaagccg
      601 gtgtgggtgt acacgacgtt gccgatccgc cccggcgtca gcatggacaa gccgtagccg
      661 aaggcgaaca tcaacgcgca cgtcaccgtg acgcgccccc gcagtgacag cggcccgcgc
      721 ggcaacttga ccggaaaccg ccgcagcggc cgcgatgagc cttcgctgac tgccgccgag
      781 tcacccggcg accggtgctc aggcgcgtcg acgtcatccg gcttcgtcat gcgccgaaac
      841 gatagcccgc gccggggacg gtgtggatca ccggtgggtt gcccagcttc cgccgcagat
      901 tcatcacggt cacccggacc gagttcgtga acgggtccgc gttctcgtcc catgccttct
      961 ccagcaactc ctccgcgctg accaccgtgc cctgttccga acgcatgagc acgtccagca
     1021 ccgtgaactc cttgggcgac aacgagagcg gctggccgtc acgctccacg taccgtttcg
     1081 ccgggtccag ccgcagccct tcccggtcgc gcaccggcgg caccgcgcga tgtgcccgcc
     1141 gcgacagcgc gtgcactctc gcgaccagtt cggcgaacgc gaacggcttc gtcatgtagt
     1201 cgtcggcgcc gaggccgagc ccgtccacac ggtcccgaat ggacgcggcg gcggtcagca
     1261 tgagtacccg tgtctcgccg tccccggcga caatccggcg gcagacctcg tcaccgtgca
     1321 ctttgggtaa gtctcggtcg aggacaacca catcgtagcg atgcacggcg atccgctcca
     1381 tcgccgcgtc gccgtcgtag cagacgtcga cggccatgtg catgtgtcga aggccctcag
     1441 cgatggcatc ggcgagcatc tcctcgtcct cggccacaag aacccgcatg ctaccccttc
     1501 ccccgtacgc gcagtctgta ctgagggtgg cataaattcc agataaaggt tgctcttatc
     1561 acccggctat gggcctttcc gtacacctgt caccatgcgc gtttcgttgc tggccggcat
     1621 catcgcggcc ggagtgtggt gcgcgttgat ggcacacacc taccgcctgg accttgaggt
     1681 atatcgtata ggggttcagg cgtggctgga tggtggtgac ctgtacgggc ggcttcccga
     1741 cacgtccatc gggcttaatc tgccgttcat ctacccaccc gtcgcggcgg ctttgatggt
     1801 tccgctgacc gtcattccgt tccctgttgc caccatcatc ctgacggcgc tgaccattgt
     1861 tcttgtctcc gtcacgctgg ccatcacgct gaaatccgtg gggctgtctc cgcgttgggt
     1921 ggcgctgctg cctgcggcga tcctgcttga accggtccgg accacgatgg cctacggcca
     1981 gatcaacgtg atcctgatgg cgctggtggt cgcggactgt ctgattgaga atcctcgctg
     2041 gcggcgcgga gttctcgtgg gtattgccgc ggcgatcaag ctgactccgt tggcgtttct
     2101 cctgttcttc ctcattcgac gggaccggcg cgcggcagtg acgaccatca cttctttcct
     2161 gggcgcgacg gctgtcggat ttgtcgtttc ctggagttcg tcggtgacct tctggaccga
     2221 tgcgattttt cacaccgagg acaaagtcgg cgtcgggtac atagcgaacc agtccatcct
     2281 cggtgtcctg ctccgcctgg acgtcggcaa ggcgttgtgg ctggtcctgg tggcggtggt
     2341 gctcgcagcg gctgtgtggg cgatgagaac cgcaaccgct cccatggcct tcggcatcac
     2401 tgcgctggcg atgctgttgg tgtcgccgat ttcctggtcg caccattggg tgtggtgtgt
     2461 gccagtgctg gtgattttcg ccgcacaggg ccagaaagtc ctcgcggcgg tcggcgcggt
     2521 cctcttcgcg gtcgggccgc actggtggtt cgagcaggtc accaccccga ccctcgcgca
     2581 gcaggtcatc gtcgacctgt acttcctctt cgccgttgcc gcggtcgctg tgcttgccta
     2641 ccaggcaaag cgtgggcgta cggtggatag cctcgagcca accccggctg gtcagctcac
     2701 cgtcgttcag ggggcgtgaa agcttttccg tacactgcgc ccatgcgcgt ttcgttgctg
     2761 gtcggcatca tcgcgggcgt ggtgtggtgc gtgtggacac ggcatacgta cgggcaggac
     2821 ctggaggtat accggctggg cgtccaggcg tggctcggcg gtggcgacct gtacggacgg
     2881 cttcccgaca cgtcgatggg gatcagcctg ccgttcatct atccgccggt ttcggtggct
     2941 ttgatgctcc cactgacgtt tgtcccgctt tctgttgcca ccatcatcct gacgacgctg
     3001 accattgttc tcgtctcggt cacgctggcc gtcaccctga aggcagtcgg ctggtcgcct
     3061 cgctggttgg ccgtgctacc agtggcgatc ctgctcgaac ccgtctggaa gacggtgaac
     3121 tacggccaga tcaacgtgat cctgatggcg ctggtggtcg cggactgtct ggttgagaat
     3181 cctcgctggc ggcgcggagt tctcgtgggt attgccgcgg cgatcaagct gactccgttg
     3241 gcgtttctcc tgttcttcct catccggcgt gaccgtcggg cggcgctgac gaccgtcatc
     3301 tccttcctgg gcgcgacggc tgtcggcttc gccctgacct ggagttcgtc ggtgaccttc
     3361 tggaccgacg cgattttcca caccgacgag aaagtcgcag tcggtttcgt cgcgaaccag
     3421 tcgactctcg gtgtcctgct ccggctggat atcggcaacg gtgtgtggct ggcgctcgtg
     3481 gcggtgctcc tcgcgctggc tgtgtgggcg atgagaactg caaccgctcc catagccttc
     3541 agcgtcacag cgctcgcgat gctgttggtg tcgccgattt cctggtcgca ccactgggtg
     3601 tggtgcgtcc ccatcctggt gattttcgcc gcgcagggcc accggatcct ggcggccgtc
     3661 ggaacgattc ttttcctgct cggaccgcaa cggtggttcg agctgacctc gcagccgacg
     3721 atcctccagc aggccctgat cgactcgtac ttcctcttcg ccgtggtggc gatcgtggtg
     3781 ctcgcctgcg ggacgaaacg gtggcacgcc ctggatcgcc cgccgcgcgc ggcggatcag
     3841 cgtctcacgg ctgttccagg aacctgacga tcaacggcga gatctcgtcg aggtcctcct
     3901 ccagcgcgaa gtgcccggtg tcgaacaggt ggacctcggc gtccggcacg tcgtcgcggt
     3961 accgctcagc gcccgcggcc aggaagaacg ggtcgttgcg gccccagagc accagtgtcc
     4021 gcggctggtg gtcacgcagc caggcctgcc accgcgggta gagctcgacg ttcgagtggt
     4081 agtcgaacgc gaggtcgacc tggatcttcg cgcgccccgg ccggtcgagg aagtactggt
     4141 cgagcaccca gccgtcgggg gcgatcgggc cacgcgcgcc ggtctcgtac tggctgcggg
     4201 tgaactgctc ggtcaacatg ccgcgcagct gcgcctcgtc gcgactcccg atgaactccc
     4261 tggccagctc gccgaggccg tcctcgtagg cgttgccgtt ctgcacgatc agcccggtga
     4321 tccactccgg gtgcctggtc gccagccgga agccgaccgg agcgccgtag tcgaagacgt
     4381 acagggcgaa ccgggacagc ccgatggcct ggacgaactt ctcgacgacg tcggcgagga
     4441 agtcgaacgt gtagtgggcc tcgggcgcat cgctgtggcc gaagccgggg tagtcggggg
     4501 cgacgatgtg gaaccggtcc ttcaacgcgt cgatcaggcc cctgaactgg tgtgacgccg
     4561 acgggaaccc gtgcaacagc agcagcgtcg gtgcgtcttt cggaccggct tcccggtaga
     4621 acacgcgcgt gccgtcgacc tgcacggtct tgtgttcggt ctggtgtttg accgtcatct
     4681 cacatgcctc cttggctcaa gttcacatta gcctaatgcg tgaaggaggt gatgtagcat
     4741 tagtcatatg gacatggtgg tgggcgagca gctggcgatc gacctgatca acacgcgcac
     4801 gtccgaaggt gacctgacag cgaccgcgga ctcgttcgcc cgctggctca aggccgaaga
     4861 tggtcgcctg accaggcccg acgccccgga tctggacgcc atccgacagt tgcgaacgca
     4921 cgtggccgcc gccgtggcac aggcccgcca aggcctggag ccgcccgccg acgcggtgga
     4981 cgcgctcaac tcggccctcc gctcggcgcc cgcgtaccgc tcgctcgcct gggacggcca
     5041 cgccatgacg accgccgtgc accgcactgg cgacgagaac gcccaactgc tcgccgaact
     5101 ggccgaagcc gcggcggagt tgctcaccag tccgtcggtg accgagatcc gctcatgcga
     5161 aggcccggac tgtctcctga tcttcctgcc cgcccacccg cgccgccgct ggtgctcacc
     5221 gagcctgtgc ggcaaccgcg tccgcgtctc ccgctactac cagcggcaca agtcctagct
     5281 gtcgaggttc acgggactga aagccgcagc cgatgcgccc ggacgacgca ccgcgcccgg
     5341 gctggtcgga ccgaattgcc cagtaaccct tacggcgcac cgccgcggaa gtcagagtga
     5401 gggccaactg actgactggg gagatcgacc gctaccagac tcgggctctg tagaacccgg
     5461 cagtgaaccc tcgccccacg cggggcgggg cgagggttca gcttcgttcg gccacgctgc
     5521 gctcgacgca gaactcgttg ccctccgggt cgtgcatgac cacccagccg gtgccgtccg
     5581 ggttgcggtg atcgtcatgg atcgtcgcgc cgatcgtgac caggcgggtg acctcctcgt
     5641 cgcgcgtgct gtccggccgc aggcagatgt gcatccggtt cttgatcgac tttgattccg
     5701 ggacctgctg gaagaacatg ttcatgccac cgccgaggtc gatcgccacc tcggggtctc
     5761 ccggcttgtc gtcatcgccg agcggcttgc cgtacacctt gctccagaac tgggcgaggc
     5821 cgtacgcgtc cagcgcgtcc agtgcgacgt tgtggataga cgaaaccatt cgaccatcca
     5881 agtccagccg ggcggacccg gcaaacggat taccagccgg gcaggtcgtc gaccggtttc
     5941 gtgttcgcct cgtgccgcgc gatcgtgccg tccagtgccg tcgccaggtc gacaccggtc
     6001 tggtcggcca ggttgatcac ggtgaacgcc aggtcggcca agcgctgctc ccagccttcg
     6061 gtcgggcgga acgggcggcg cccgttcgcc gtggcggcaa gcacttcgtc ggacaagcgg
     6121 cccatttccg acaacagcgt gagggtcagg gacggcgcgt tcgcgtgcag gccgagtttg
     6181 tcagcggcct gggcaacctt ctgctgtact tctcgcacgg gctagacact agtggtcacg
     6241 accggtagta ccccagtccc ggctcagcgc ctcctcgatc agcgtttcca cgatcttgct
     6301 ctccggcacc gtcctgatca cctcgccccg gacgaagatc tggcccttgc cgttgccgga
     6361 cgacacaccg agatcggctt cgcgcgcctc gccgggaccg ttgacgacgc agcccatcac
     6421 cgcaacgcgc aagggcaccg ggaatccctc gaacgcggcc gtgacctcct ccgccagctt
     6481 gtagacgtcc acctgggccc gaccacacga cgggcacgag acgatctcca gccgacgcgg
     6541 ccgcagcccg agagattcca ggatctgggc acccaccttg acttcctcga ccggcggagc
     6601 cgacaacgac acccggatcg tgtcgccgat cccggccgcc agcaggacac cgaacgcgac
     6661 cgacgacttg atcgtgccct ggaaccgcgg ccctgcctcg gtcacgccga ggtgcagcgg
     6721 gtagtcgcag cgcgccgcca gtttgcggta cgcgtcgatc atcaccaccg ggtcgtggtg
     6781 cttgaccgag atcttgatgt cccggaaccc gtgctcctcg aacagcgagc actcccacag
     6841 tgccgactcg accagcgcgt ccggcgtggc cttgccgtac ttctcaagca ggcgcttgtc
     6901 cagcgaaccg gcgttgacgc cgatccggat cggcacgccc gcgcctgccg cggccgaggc
     6961 gatctcccgc accttgtcgt cgaactgcct gatgttgccc ggattgaccc gcacggcggc
     7021 gcagcccgcg tcgatcgcgg cgaacacgta cttcggttgg aagtggatgt cggcgatcac
     7081 cgggatcgtg gcgctcttgg cgatccgcgc cagcgcctcc gcatcgtcct gcgagggcac
     7141 cgccactctg acgatctggc agcctgccgc ggtcagctcg gcgatctgct gcagtgtcgc
     7201 gtccacatcg gacgtcacgg ttgtggtcat ggactgcacg ctcaccggtg cgttcccgcc
     7261 gaccgggacg tcgccgacga gcacctgacg ggactgcctg cgcagcgacg gcgggccaag
     7321 ctgtaccagg gtcaagacaa tgcctccagg cgtttgagca cggtcgtggc gataccggcc
     7381 gcgtcaaggc cgtgtgcccg caggatctcc gagcgggacg cgtgtggcag gaacctgttc
     7441 ggcaacgcga acgtcgccgc gcacgtgtcg gaaccgttgg cagccaacgc ctgtgcgatc
     7501 cgaccgccca gggcgcccgg tgtcgtggtg tcctcgacgg ccaccacgag tcggtggcgg
     7561 cccgccagtt tcagcagcga cgggtcgacc ggcgcgatcc agcgcggatc gacgacggtc
     7621 accggcacac cgtgctccac caggtcgtcc gcggcctcga gacacgccga cgccagcgac
     7681 cccaccgcga ccagcaacac ctgtgcggta gggctttccc gcaggacgtc gcagtgtccg
     7741 gtccgccgca cggccgggat gtcctcgccc gcggcggcct tgggataacg cacgacggtc
     7801 ggcccgtcgt gcacgtcgac cgcttcccgc agcagctccc gcaaccgggc cgggtcgcgc
     7861 gggctggcca gccgcaggcc cggcacgacc ggcaggatcg aggagtccca catgccgtgg
     7921 tggctcggcc cgtccggccc ggtcaccccg gcccggtcga gtacgaacgt gaccggcagc
     7981 cggtgcaacg ccacgtccat cagcacctgg tcgaccgccc ggctcaggaa cgtcgagtac
     8041 accgccacga ccgggtgcat cccgcccagc gccaggcccg ccgcggaggt caccgcgtgc
     8101 tgctcggcga tgcccacgtc gaacagccgg tcggggaacc gggctgcgaa cccggccagc
     8161 ccggcgggtt cggccatcgc cgcggtgatg cagaccaggt cgtcccgccg cgcgccgagc
     8221 gccgtgatct cgtcggcgaa caccgccgtc cacgtgggtt tgcggacggc accggctggt
     8281 ccgaccgcgt gcagccggtc ggcttcgtcc tgttcggctg ggggatggcc ctttcctttg
     8341 cgtgtcacgc agtgcaccac gaccggccgg ttcagccgga cggctctgcg cagcgcgtgc
     8401 tccagatcgg ggatgtcgtg cccgtccacc gggccgatgt aggccaggcc catgtcctcg
     8461 aagatgttgc tgcttccctc gtaacgcagc acggcgagat ggctggcgat gccaccgatc
     8521 gtcggtgcgt acgagcggcc gttgtcgttc agcacgatga ccatcggccg tttcggcgcg
     8581 ccaccgatgt tgttcaacgc ctcccagcac atcccaccgg tcaacgcgcc gtcgccgaga
     8641 atcgcgacca ctcgccgctg ggactcccgc aacgagaacg ccttcgccag gccgtccgca
     8701 taggacagcg cggtggacgc gtgcgagttc tcgatcacgt cgtggtcgga ctcggagcgg
     8761 gacgggtaac ccgacagtcc gcctgcctgg cgcagcgagt cgaagtccgc cgcgcggccg
     8821 gtgaggatct tgtgcacgta ggcctggtgc ccggtgtcga acagcagcac gtcgtcgggg
     8881 gagtggaaga cgcggtgcag cgcgatggtc agctcgaccg cgccgaggtt cggcccgagg
     8941 tgcccgccgg tgcgggacac cttgtcgacg aggaagtccc ggatctcacc agccagcacg
     9001 acaaggtccg atgtggagcg ggaagccaga tcggcgtggt ccgtgatcat gagcgcctcg
     9061 ctgacggcgg cagcgtgaac tggatcgtct ccttcgccgt ttcccttgtc tccacgctga
     9121 tcgggttcag cgcggcgacc acttcgtcga ccagtcccgg cggcgcggac gcgcccgcgg
     9181 tgataccgac gacccgcacc ccggccagcc acttggcctt gatctcgctg acatcgtcga
     9241 tcaggtaggc gggcgtgccg tgccgctgcg ccagttcgac cagccgcacg gagttcgacg
     9301 agttcgtcga cccgaccacc aggacaagat cggactcctc ggcgatcgcg gtcagcgcgt
     9361 tctgcctgtt cgttgtcgcg taacagatgt cgtccgacgc agggcccttg aggtcgggaa
     9421 accgggcccg cagcgccgac accacctcgg cggcctcgtc gaccgcgagc gtggtctgca
     9481 tcaggtagga gacgttcgac ggatcgggga cgtccagtgc gccgacaccc tccgggctct
     9541 cgagcagcac ggtctggtcg ggtgcctcgc cgagggtgcc ctccacctcc tcgtgcccgg
     9601 cgtggccgac caggacgacc gtgtcaccgc gggcggcgaa ccggcgtgcc tccgcgtgca
     9661 ccttggtgac cagcgggcac gtcgcgtcga cgacgtcgag ggcgcgccgc tccgcctcgg
     9721 cgcggaccgc gggggagacc ccgtgcgcgg agaacaccac ggtcgagccg tccggcacgg
     9781 catccagttc gtcgacgaac accgcgcccc gcgtctgcag gtcagcgacc acgtgcttgt
     9841 tgtgcacgat ctgtttgcgt acgtagacgg gtggttttcg gcgccgcagc acctcttcga
     9901 ctatctcgat cgcgcggtcg accccggcgc agaacgaccg tggcgacgcg agcaacacct
     9961 tgacctgcat ggcgaagccg ccccttcgac gaatgactgg tcagtggtcg cgatgagtga
    10021 ccaggccggc cagcccggcc agttcggtgg cggcagcggc gaccggatcg gccgaccgca
    10081 gccgccgcac cgcacgggcc agccggtcgt cggcctgttc ctggctccac gcccggccac
    10141 cggccaggtc gatcagctcg gcggcgcgtt cgatgtccgt gcccgacagc ggccggtcgc
    10201 agtggtacag ctcgcccagc tcctgcccgg cgatggtgtg cgaggtcagt gcggcgacga
    10261 ccggcaggga cttcttgcgg ttgtgcaggt ccgagtacac cggcttgccg gtcgactcgg
    10321 gcctgcccca gatcccgagc aggtcgtcga ccagttggaa agcgagcccg agctcgtcgc
    10381 cgaagcccca caggtggtcg acctgcgtcg cccggccgcc gccgaacagc gccccgatcg
    10441 agcaggacgc gctgatcagc gcaccggtct tgcagcgcgc catcgtcacg cactcgtcga
    10501 gcgtgatgtc cctgcggtcc tcgaactcga catcgagact ctggccgtcc accagggcct
    10561 ggatcgccgc cgagaggctg cgcatggcct cgacggagtc ggggtgcccg ctcgcggcga
    10621 gcacgtcgaa cgccagcgtc accagcgagt caccggccag gatcgcggca ctgcggccga
    10681 acacgctcca cgccgtcggc cggtgtcgcc gggtgacgtc gccgtcgatc acgtcgtcgt
    10741 gcagcaggga gaagttgtgc accagctcga tcgcgaccgc ggcgggcacg acagccgacg
    10801 cgtcaccgcc gaccgcctcc gccgcgagca gcgtcagcgt cggccgtaat gccttgccac
    10861 cggacgaatc cgacggcctg ccgtgctcgt cccaccagcc gtagtggtac ccggcgatcc
    10921 tgcgcatcga gccgggcagc gtgtccaccg cagcacggga agccggttcc accaggtccc
    10981 tgctccaggc aaggacctcg cggggtgtgc ggctttcggt tgccacttcc cgagtggtca
    11041 tcgcgtcaac gcccgagctc gacactctcg aggatgccga gcgcgtccgg caccatcacc
    11101 gcgaccgagt agtacgcact gaccagatag gacatgatcg cgcgctcgtc gacgcccatg
    11161 aaccgcacgt tcaggcccgg ctcgtactcg tcgggcaggc cggtctggtg caggccgatc
    11221 acgccctggt tcttctcgcc ggtccgcatc gcgaggatcg aggtgcggcc ggtctcgctg
    11281 atcgggatct tgtcgcacgg cagcagcggg atgttgcgcc aggtctgcac gaccttgccg
    11341 tcgagttcgg tggtgttcgg gtagatgccc ttgctgttgc actcacggcc gaacgcggcg
    11401 atcgccctgg ggtgcgccag gatgaactgg gtcttgcggc ggcgggagat caactcgtcc
    11461 atgtcgtcgg gcgtcggcgg gccggagtgg gtgtggatgc gctgcttgag gtccgcgttg
    11521 tggagcagcc cgatctgccg gttgttgatc atctcgtact cttggcgctc gcgcagcgcc
    11581 tcgacggtca gccgcaactg ctgctcggtc tggttcatcg gctggttgta cagatccgcc
    11641 accctggtgt ggatccgcag caccgtctgg gtcacgctca tctcgtactc gcgcggtttg
    11701 agctcgtagt cgacgaaggt tcccggcagc tggtactcgc cggacagccc ggacgccagc
    11761 tcgatctcgg cctcgccctt ggcgttgctc gccttgccgc gcaaccgcgc gagttcggcc
    11821 aggtgcgcct gcagtgtctc ggactgcccg gtgatgcggt cgaactcctg acgggacaac
    11881 gtcatcgcga tgcagcgagt cttggccttg accgtgaagc tccactcgtt gcggtgcccg
    11941 gtcagcgcct gctcgccgaa gtactcaccc tcgccgaggg tgtcgagcac ggcctccacg
    12001 ccgtactcgc caagtccgat cttgctggcc ttgccgtgcg ccatcagcac gagccggtca
    12061 gcggtttgtc ctttctggat gatcaggtcg cctgcctcga actcctgctg ctcgaaccgg
    12121 ccggcgatcg cggccagcgc ctcgtcgtcc tcgaacgagc gcagcagcgc cagttcacgc
    12181 agttccggcg ggacaacctg aacgcgtccc tcgctgaggg tgaagctgac cagtccatcc
    12241 ccgatggcgt acgtcagtcg ccggttgact cggtacgcac caccttcggc ctgtacccac
    12301 ggcaggacgc gcaacagcca acgcggcgtg atcccctgca tctgcggtac ggacttggtc
    12361 gtcgtcgcca gatttcgcgc ggctttggtg ccgaggctca tctgctgctg cgactggggg
    12421 ttctcgacct gtgtcacgtg ttcgaccgcc ttgttctagt tgatcagttg agatgtgggg
    12481 acggtgtcgg ggattcgacg ctggccgatg ccgaatgagt catcggccag cgcccactcg
    12541 gccacctttg accggtgggg gcaccacgcc ttgcgttcct ccacccagcc gctgggagcg
    12601 ccgagggccg gttgggagag tcaggtgtgg caacggccaa aggcctggtg gccgagggga
    12661 aagggatgac cgacctaccg ccgccggatc actccacgcg gccgagttcg acgttctcca
    12721 gcacgccgag tgcgtcgggt accaggatgg ccgccgagta gtaggcgctc accaggtacg
    12781 acatgatggc tttctcgttg atgttcatga aacgcaccga caggccgggc tggtactcgt
    12841 ccggcaggcc ggtctggtgc aggccgatca cgccctggtt ctgttcgccc acccgcatcg
    12901 cgatcatctg ggtggtcctg gtgtcggtga tcgggatctt gttgcacggc agcacgggga
    12961 taccgcgcca cgacggcatc tggtggccgt tgaagtcgat gctctgcgga tagaggcccc
    13021 gcttgttgca ctcctggccg aacgcggcga tcgccttcgg gtgcgccagg atgtaactcg
    13081 ggtccttcca caccgtggcg agcagttcgt ccatgtcgtc gggagtcggc gggccgctgc
    13141 gggtggggac gcgctgtttg aggtcggcgt tggccagcag gccgaagtcg ccgttgttga
    13201 tcagttcgtg ttcctggcgt tcgcgcagtg cctcgatggt cagccgcagc tgctgctccg
    13261 tctggttcat cggctggttg tagagatccg cgaccctggt gtgcactcgc agcacggtct
    13321 gcgcgacgct gagctcgtat tcccgcggtg agagttcgta gtcgacgaac gtgccgggca
    13381 gttccggttc accgtcgtga ccggatgcga ggttgatctc cgcttcgccg tgtacgttct
    13441 gtgccttttt cgggctgtcc cggtacgcgg tgacgtgatc gcggagcgcc tcggactgat
    13501 cttgcaattc ctggaatgac tgtttcggca acgcgagaat cgttaccggt gtcacggcct
    13561 tggcggtgaa ctcccagatg ctctgatcct ggacgagcgc ctggtcgccg aaatagtcgc
    13621 catcgaccat cgtgctcagc acggtctggt cgccgtactc gccggtgccg atcctgttca
    13681 ccttgccgtg tgcgacgacg tagaggtggc cggcctcgtg gccgaactcg gcgatcacgt
    13741 cgccgggctg gtactcctgc tgctggaatc ggtcggccag cgcgttgagc gcctcctcgt
    13801 cgtcaaaagt gcgcagcaga gccagttcga cgaggtcggg gccgacgacg tgtactcgcg
    13861 atccggtgtt ggtgaccgcg atccggccgt cgccgacggt gtagctcaac cgcctgttga
    13921 cccggtacgc gccaccctgg gcctggaccc acggcagaac tcgcagcagc cagcgcgagg
    13981 tgatgctctg catctgcggg acggatttgg tggttgtcgc caaattccgt gcagccgctg
    14041 tcgccaggct ctgctgttgc tgtccgttct ctacgtcaag attcgagtcc accgtgtcgg
    14101 tcacaacggt ccgccattct tcctagtcgg gttgcgtgga cagtgaaaat gacatgggtg
    14161 tcggtgataa ttggctcgcg acaaagaggg aacacccttt cgtgttccgc tgaatgatcc
    14221 agttcgaacg gtgccaggac atgacgctag caccacgttt cgagcacgcg cagtcaccca
    14281 aaaggcttgc ccggccagcg gaaaggaatc atgggacgat tcacgctttt cgatgcatga
    14341 cgcccaataa gcgaaccgaa agtgccgttg cgtgaaacgt cgttcactcg ccagtaccaa
    14401 gtcgatacga caaacgtgtg tacccgtgtg ggcgacgccg acccggtgct agtccatccg
    14461 gggcagcctc gcctgatcca ttgaggcgag aatcatggcg gccatcctcg cggggtcgcc
    14521 ctgctccgga tgcagtacca gttcagccga cagcggcggc tcgtacgggt cgtccacgcc
    14581 ggtgaacccg gtgatctcgc ccgccctggc cttcgcgtac atccccttgg gatcacgggc
    14641 ctcgcacgtc tcgatcggcg tgtccacgaa gacctcgaca aacggcaggc cggccaggtc
    14701 gtgtgcggca cgcaccaggt cgcggtcggc gcggtacggg ctgatcaagg acaccaccgc
    14761 gaccacgccc gcgtcggcga acagccgcgc gacctcaccg acccgacgga cgttctcggc
    14821 ccggtcagcc gcgctgaagc ccagatcggc gttgaggccg tggcgcaggt tgtcgccgtc
    14881 cagaaggtag gccggacggc cggacgccac cagtcggcgt tccagttcca ccgcgacggt
    14941 cgacttccct gaggccgaca ggcccgtcag ccagaccgtg cagccgctgg tgccgcgctc
    15001 ggcacgctgg acggacgtgg agtgccagac caccgactgg gcgggcccgg tgatcatgcc
    15061 cgcggcgacg gtgttgttgg tggtctcgtc caccaggatg aaactgccac acgcccggtt
    15121 gcgccggtac gcgtcgaaca gcagcggctg ccgtgtgcgc agcctgaccc ggccgatctc
    15181 gttgagcgac agggactccg cggtctcgtc acggtgtagc gtggtgatgt ccagccggta
    15241 gtccagcgac gtgaccacgg ccttggtcga tcgcgttgtg ctgaccactg tgtactgggc
    15301 gtccgggctg agctcgccgt gttcggtcag ccagcagacc atcgcgtcga tgtccgtgcc
    15361 gacgtgcggc cggttgttcg ggcggcagat caggtcgccg cggccgacgt ccaggtcgtc
    15421 ggccagccgc agggtgaccg cctgcggcgg gaaggcctcg gtgaccggct gcccgccagg
    15481 gccgaggatg tcgctgacgg tcgtggtgaa cccggagggc agcacgagca cctcgtcgcc
    15541 cggcttgaac acaccgcccg cgatggtccc ggcataacct cggaagtcct ggtggcggat
    15601 gacgtactgg accgggaagc gggcgtcgat caggttgcgg tcggagctga cgtgcacctc
    15661 ttcgaggtga tgcagcagcg atgttccctc gtaccacggc atcgaggtgc tgcggtgcac
    15721 gatgttgtcc ccgagcagcg ccgacaccgg gatgaacgtc aggtccggca cggccagctt
    15781 catcgagaac cggcggaact cctcacggat ctcctcgaag cgttcccgcg accagtcgac
    15841 caggtccatc ttgttcacgc acaccacgat gtgcgggatg cccagcaggc tggcgaggaa
    15901 cgcgtgcctg cgcgactgtt ccagcacgcc tttgcgggcg tcgatgagga ccagtgcgag
    15961 gtctgctgtg gacgcgccgg tgaccatgtt gcgggtgtac tggatgtgcc ctggggtgtc
    16021 ggcgatgatg aacttccgct tgggcgtggc gaagtagcgg taggcgacat cgatggtgat
    16081 gccctgttcg cgttccgcgc gcaggccgtc ggtcagcagc gccaggttcg ggtagtcctc
    16141 gccccggtcg cggctggcgc gttccagcgc ggccaactgg tcggcgaaga tggtcttcga
    16201 gtcgaacagc aggcggccga tcaacgtgga cttgccgtcg tcgacgctgc ccgcggtggc
    16261 gaggcggagg aggtggggca tcagaagtag ccctccttct tgcggtcttc cattcctgcc
    16321 tcggagatcc ggtcgtccgc cctggtcgcg ccgcgctcgg tcacccgggt cgccgcgacc
    16381 tcggccacga cctcgtccgg tgtggcggcg gtggattcga cgcacccggt gcaggtggcg
    16441 tccccgaccg tgcggaaccg cactgacgcc tcgaacagat cctcgtccgg cagcaccgtc
    16501 acgaacctgg tgtgtgccaa cagcatcccg tcccgctgga acacccgtcg ccgatgcgcg
    16561 tagtagatgg acggcaggtc gatgtgttcg tcccggatgt actgccagat gtccagctcg
    16621 gtccagttgg acaacgggaa cacccggatg tgctcaccgc ggcggtgtcg tccgttgtag
    16681 acgttccaca gctccggccg ctggttgcgc ggatcccact ggccgtactc gtcccggaag
    16741 ctgaagaccc gttccttggc gcgtgccttc tcctcgtccc ggcgcgcacc gccgaacacc
    16801 gcgtcgaacc ggttttcgtt gatggcccgg agcaaggccg tggtctgcag gcgattgcgg
    16861 ctggcacgcg gcccggtctc ctcgaccaca cgcccggcgt cgatgtcgtc ctggacccgg
    16921 ctgaccacca gtcgcacacc tgtcgactcg accgtgcggt cccggaactc gatgacctcg
    16981 tcgaagttgt gcccggtgtc cacatgcatc accgggaacg gcggcggcgc gggccagaac
    17041 gccttggccg ccaggtgcag catcaccacg gagtccttgc cgccggagaa cagcagcacc
    17101 gggcgctcga acgtggccgc gacctcgcgc agcacgtgca cggattcggc ctccagcgcg
    17161 cgcaggttgg tcagctcgta cgagatcgcc acgctcaaaa actagaacat gttattgcgt
    17221 gtggtcaatg ccaggggtta gctggggaca tggacgacat gcgtgaggtc gaggagatcc
    17281 gcaggctgaa gtaccgctac ctgcgtggcg tcgaccagaa gcggtgggac ctgcttgagg
    17341 cggcactgac cgaggacgcc gtggccgact acgggaccag ggcgatgggc gagccgctcg
    17401 tgctcaccgg gcggcccgcg atcctcgact tcatgcggca gaacctggac ggcgacaaga
    17461 tcatcacctt ccacttcacc ggccagccgg agattgacat cgtcggtgac acggccactg
    17521 gaacctgggc tttcgaggac acggtgatca tcaaggaaca ccgctcggtg atcaagggcg
    17581 cggcctacta cgaggaggag tacgtccgtt cactcgaggc tggctggcag atcaagcgca
    17641 tcttctacaa gcggatctac gaggtgatgg tgtccatgga cgacctgccc agcatgcggt
    17701 tcctcgccgg tgtttgaccg atgttagaac gcgttctagt ctgagtcggt gctcaccgag
    17761 tccttcgccg ccgcgatcgc cgacgccgag aagatcgtcg ccgaagcgcc gcacgtgctg
    17821 accgagcagg acctgaccga gggctacgac tacctcgcgg gcaacatcaa ggcctcgctg
    17881 cagatggcgt gggcctacga ccgcgactac ccgtacttcg tccagtccac cgggccctac
    17941 accaagatgg gcctggacaa cccggacacg ttgtacttcc acgccaacat ccgcgacgac
    18001 gcggagtacg tggtgaccgg gcggcgcggc agcacagcgg acctgagctt ccaggtgctc
    18061 aacggcgact actcaccggt ggacgtgccg gacagcctga ccgcgttcga cgaccgggcg
    18121 ttcgagatcg ccgaggacgg cacgttcgag atccggttcg ggccgggcga ggccgggccg
    18181 ggctacttcc cgctcggcac gggctccgcg atgctggtcg tgcgcgaggt ctacagcgac
    18241 tgggcgggcg agcagcgcgg aatgatccgg atccggcgag ccgacaccac cgggtccgcg
    18301 ccgcccgcgc ccacgaagga cctgatggcc aagcggtacg cggtcgcggg caggatgctc
    18361 accagcaggc tcaagacgtt cctggcgttc ccgaagtggt tctacctgaa cctcccggtg
    18421 aacaccatga ctgagccccg ctccaccccc ggcgggctga ccacccagtt ctcctcggtc
    18481 ggccactacg acctcgccga cgaccaggtc atgatcatca ccgtgccggt gtccgatgcg
    18541 ccgtaccacg gcttccagtt gggcagcatg tggtacgtct cgctggacta catcaaccac
    18601 cagaccagcc tgaccgccga ccaggccagg gtcgacccgg acggccggat caggtacgtg
    18661 gtcagtgaac gagacccggg actggcgaac tggatcgaac gcaccggtca cgccagggga
    18721 tatctgcaga tccgctggca acggctgtcc cgtgacctga aacccgagga cgggccggag
    18781 gtcgaggtcg tccccttcgc cgaactgccg cagcgactgg cgttccacca ggaagcacgg
    18841 atcacgcccg agcagtacgc cgaacggatc gccgcccgcc aggctgcggt cgcgaccagg
    18901 atggtgggct gatgttgtta caggacaagg tcgtcgtggt cgccgggatc gggccggggc
    18961 tgggccgctc gatcgcactg cggtgcgcga gccagggcgc ggacatcgtg ctggccgccc
    19021 gcacggaatc ccggctgacc gaagtggcca aagaggtcac ggaactcggc aggcgcgcgg
    19081 tcaccgtgcc gacggacatc tcgtccgaag cggacgctgc ccgcctcgcg gacaccgcga
    19141 tggagtcgtt cggccgggtg gacacgttgg tgaacaacgc tttcgccatc ccgccgatgg
    19201 gtgatctcga cggtgtcccg ttcggcggga tccgccaggg cttcgagacc aacgtcctcg
    19261 gcgcgctgcg gctgacgaac ctgttccgcc ccatgctcga agccagccgc ggctcggtcg
    19321 tgatggtcag ctccatggtg atccggcact ccaaacccac gttcggcccg tacaagatga
    19381 ccaagtcggc gttgctggcg atggcacaga gcctgtcgac cgaactgggc cccaagggcg
    19441 tgcgggtgaa caccgtcgcg cccggctaca tctgggcgga caacgtgaag tactacttcg
    19501 actacctcgc caaggaacgc gggatcaccc cgcagcaggt ctacgacgag gtggcgtcga
    19561 acatcgacct gcgcaagctg cccgagccgg acgaggtcgc cgacacgatc gtcttcctgg
    19621 cctcggacct ggccagcgcg gtcaccggcc agtgcctgga cgtcaacggc ggcgagttcc
    19681 accactagga gcccacagtg gacattgaat cgctgcacgc gtcggccacg aagatcaccg
    19741 ggctgaccga cttcggggac caggagtacc tggacggcct gtcggtgctg gtggactcct
    19801 accaccggga agccgggctg accgagttcg gcctgcgcgt gcagcgcgcc gggctgcgtt
    19861 cggcactggt ggcccggctg ctcagcgagg ccgcgtggca gcggcacccg gagcacgcgg
    19921 cggtcccgat cgagcggccg atcttcgtga ccggcctgcc ccgcaccgga accaccgcgt
    19981 tgcaccggct gctcaccgag gacccggcgc accagggcct ggaactgtgg ctcaccgact
    20041 tgccgcagcc gcgcccgccg cgcgagacgt gggaagaaaa cccgatgtac cagcggatcc
    20101 aggccgggta cgagcagcac cacgtcgagc acccggagtt catgggactg cactacatca
    20161 ccgccgacat ggccgaggag tgctggcggc tgctgcgtca gtccatgatg tcggtctcct
    20221 tcgagtgcct tgcctacgtg ccaacgtatt cggagtggct cgccggacgg gactggacgg
    20281 ccgcctacca ccggcaccgg cgcaatctcc agctgatcgg cctgccggac gccgggcgcc
    20341 ggtgggtgct gaagaacccc agccacctgt tcgcgctcga cgccctcatg gcggcctacc
    20401 cggacgcgct ggtgatccag acccaccggg agccccgcac gatcatcgcc tcgatgtgca
    20461 gcctcgccga gcaggccacg gacggctggt cggacgtgtt ccgcggttcg gtcatcggcc
    20521 gcacccagct ggacctctgg gcgcgaggcc tggagaagtt caccgccgac cgcgtgaaac
    20581 acaatccggc ccagttctac gacgtgcagt acgacgaatt cgtggccgat cccctcggcg
    20641 ttgtcacgga cgtctaccgc catttcggcc tggcgctgac cgacggcgtc ctcgacgcca
    20701 tgaacaccgt gcacagcagc ggcgaccgtc gccgttcaca ccgctacgac ctggccgact
    20761 tcgggctgac ggcggcgcag gccgacgccc ggttcactcc gggacggtga tgtcgccgag
    20821 ttccccgatc tccgctccag tccgcagtct gtctacttat gattgtgcat gctttgtcgc
    20881 accgtcctgg ctctgggtac cgcgctggcc ttgtccgcgt gtacccagcc ggtcgaggga
    20941 accgccaccg ccaatgcccc cgttgaagcg cccgatcccg cctgtccagg caaaaccgcc
    21001 tccaccctgc tgggggcaag cgaggacaca ctgcgcgcct t
//
